Lasp1 (LIM and SH3 protein 1) - Rat Genome Database

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Advanced Search (OLGA)
Gene: Lasp1 (LIM and SH3 protein 1) Mus musculus
Analyze
Symbol: Lasp1
Name: LIM and SH3 protein 1
RGD ID: 68602
MGI Page MGI
Description: Enables actin filament binding activity. Predicted to be involved in monoatomic ion transport. Located in cytoplasm and focal adhesion. Is expressed in several structures, including alimentary system; bone; central nervous system; genitourinary system; and hemolymphoid system gland. Orthologous to human LASP1 (LIM and SH3 protein 1).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: AA408629; Def-4; LASP-1; LIM and SH3 domain protein 1; metastatic lymph node gene 50 protein; MLN 50; SH3; SH3P6; Tg(11Col1a1)NG; Tg(Col1a1-lacZ)1Ngma
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Related Pseudogenes: Gm4875  
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391197,689,748 - 97,729,591 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1197,689,826 - 97,729,590 (+)EnsemblGRCm39 Ensembl
GRCm381197,799,005 - 97,838,765 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1197,799,000 - 97,838,764 (+)EnsemblGRCm38mm10GRCm38
MGSCv371197,660,986 - 97,700,078 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361197,615,762 - 97,654,854 (+)NCBIMGSCv36mm8
Celera11107,449,132 - 107,487,995 (+)NCBICelera
Cytogenetic Map11DNCBI
cM Map1161.1NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dichloroethane  (EXP)
1,2-dimethylhydrazine  (EXP)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-tribromophenol  (ISO)
2,4,6-trinitrotoluene  (ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
2,4-dinitrotoluene  (ISO)
2-methylcholine  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4-hydroxyphenyl retinamide  (EXP)
5-fluorouracil  (ISO)
afimoxifene  (ISO)
aflatoxin B1  (EXP)
Aflatoxin B2 alpha  (ISO)
all-trans-retinoic acid  (ISO)
ammonium chloride  (ISO)
aristolochic acid A  (ISO)
Aroclor 1254  (EXP)
arsenous acid  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[b]fluoranthene  (EXP)
beta-lapachone  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
bleomycin A2  (ISO)
Brodifacoum  (ISO)
cadmium atom  (ISO)
caffeine  (ISO)
calcium dichloride  (ISO)
calycosin  (ISO)
carbon nanotube  (EXP,ISO)
chlordecone  (EXP)
chloropicrin  (ISO)
chlorpyrifos  (EXP)
chrysene  (EXP)
copper(II) sulfate  (ISO)
coumarin  (ISO)
cumene  (EXP)
cyclophosphamide  (ISO)
decabromodiphenyl ether  (ISO)
dexamethasone  (ISO)
dextran sulfate  (EXP)
diarsenic trioxide  (ISO)
dibutyl phthalate  (EXP)
dioxygen  (EXP)
doxorubicin  (ISO)
epoxiconazole  (EXP)
ethanol  (EXP)
fenthion  (EXP)
flutamide  (ISO)
folic acid  (EXP)
fulvestrant  (ISO)
fumonisin B1  (EXP)
furan  (ISO)
gentamycin  (ISO)
hydralazine  (ISO)
hydrogen peroxide  (EXP)
hydroquinone  (ISO)
indometacin  (ISO)
inulin  (EXP)
ivermectin  (ISO)
lipopolysaccharide  (ISO)
lovastatin  (EXP)
methidathion  (EXP)
Methylazoxymethanol acetate  (ISO)
methylphenidate  (EXP)
miconazole  (EXP)
microcystin-LR  (ISO)
naphthalene  (EXP)
O-methyleugenol  (ISO)
paracetamol  (ISO)
paraquat  (ISO)
parathion  (EXP)
pentachlorophenol  (EXP)
perfluorohexanesulfonic acid  (EXP)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (EXP,ISO)
perfluorooctanoic acid  (EXP,ISO)
pifithrin-?  (ISO)
pirinixic acid  (EXP)
pregnenolone 16alpha-carbonitrile  (EXP)
propiconazole  (EXP)
sarin  (ISO)
SB 431542  (ISO)
selenomethionine  (ISO)
sodium arsenite  (ISO)
sunitinib  (ISO)
tamibarotene  (ISO)
testosterone  (EXP)
tetrachloromethane  (EXP)
tetraphene  (EXP)
thapsigargin  (ISO)
thioacetamide  (ISO)
titanium dioxide  (EXP)
trichloroethene  (ISO)
triphenyl phosphate  (ISO)
triptonide  (EXP)
trovafloxacin  (EXP)
valproic acid  (ISO)
vorinostat  (ISO)
warfarin  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Mouse brain organization revealed through direct genome-scale TF expression analysis. Gray PA, etal., Science 2004 Dec 24;306(5705):2255-7.
2. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
3. MGDs mouse GO annotations MGD data from the GO Consortium
4. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
5. Mouse MP Annotation Import Pipeline RGD automated import pipeline
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889548   PMID:9511759   PMID:9630982   PMID:10349636   PMID:10460589   PMID:10725249   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12010804   PMID:12438746  
PMID:12477932   PMID:12520002   PMID:12904583   PMID:14610273   PMID:15004028   PMID:15138294   PMID:15465019   PMID:15489334   PMID:15782199   PMID:16141072   PMID:16141073   PMID:16416089  
PMID:16492705   PMID:17540781   PMID:17609113   PMID:17967808   PMID:18287559   PMID:18483181   PMID:18799693   PMID:19064729   PMID:19378249   PMID:19378260   PMID:19531578   PMID:20412781  
PMID:20932939   PMID:21267068   PMID:21565611   PMID:21652651   PMID:21677750   PMID:21873635   PMID:22794259   PMID:23553930   PMID:24441682   PMID:25385028   PMID:28340616   PMID:28378742  
PMID:30196744   PMID:30335684   PMID:30562941   PMID:32325033   PMID:32554809   PMID:33242526   PMID:34131132   PMID:36417873   PMID:37578083   PMID:38713618  


Genomics

Comparative Map Data
Lasp1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391197,689,748 - 97,729,591 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1197,689,826 - 97,729,590 (+)EnsemblGRCm39 Ensembl
GRCm381197,799,005 - 97,838,765 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1197,799,000 - 97,838,764 (+)EnsemblGRCm38mm10GRCm38
MGSCv371197,660,986 - 97,700,078 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361197,615,762 - 97,654,854 (+)NCBIMGSCv36mm8
Celera11107,449,132 - 107,487,995 (+)NCBICelera
Cytogenetic Map11DNCBI
cM Map1161.1NCBI
LASP1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381738,870,058 - 38,921,770 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1738,869,859 - 38,921,770 (+)EnsemblGRCh38hg38GRCh38
GRCh371737,026,311 - 37,078,023 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361734,279,894 - 34,331,541 (+)NCBINCBI36Build 36hg18NCBI36
Build 341734,279,893 - 34,331,541NCBI
Celera1733,687,074 - 33,739,007 (+)NCBICelera
Cytogenetic Map17q12NCBI
HuRef1732,821,270 - 32,873,230 (+)NCBIHuRef
CHM1_11737,261,377 - 37,313,322 (+)NCBICHM1_1
T2T-CHM13v2.01739,733,108 - 39,784,846 (+)NCBIT2T-CHM13v2.0
Lasp1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81083,290,820 - 83,331,989 (+)NCBIGRCr8
mRatBN7.21082,795,177 - 82,835,659 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1082,795,137 - 82,943,292 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1087,743,471 - 87,783,948 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01087,241,560 - 87,282,036 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01082,634,149 - 82,674,629 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01085,744,662 - 85,785,130 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1085,744,568 - 85,785,133 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01085,533,431 - 85,573,899 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41086,552,612 - 86,593,328 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11086,567,067 - 86,605,176 (+)NCBI
Celera1081,549,996 - 81,590,495 (+)NCBICelera
Cytogenetic Map10q31NCBI
Lasp1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545113,910,889 - 13,932,506 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495545113,910,891 - 13,932,506 (+)NCBIChiLan1.0ChiLan1.0
LASP1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21926,026,693 - 26,078,986 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11727,910,292 - 27,962,126 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01718,350,002 - 18,401,693 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11718,623,071 - 18,674,731 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1718,623,071 - 18,674,731 (-)Ensemblpanpan1.1panPan2
LASP1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1923,345,226 - 23,397,058 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl923,347,881 - 23,396,945 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha922,816,905 - 22,868,891 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0924,139,876 - 24,191,899 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl924,139,879 - 24,180,865 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1922,911,898 - 22,963,837 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0923,172,943 - 23,224,901 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0923,297,911 - 23,350,411 (-)NCBIUU_Cfam_GSD_1.0
Lasp1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560222,779,042 - 22,807,935 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493649014,263,973 - 14,298,951 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493649014,267,185 - 14,296,114 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LASP1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1223,222,708 - 23,267,855 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11223,222,706 - 23,267,209 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
LASP1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11667,268,442 - 67,320,473 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1667,267,940 - 67,320,373 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607738,264,217 - 38,316,231 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Lasp1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247953,842,242 - 3,868,217 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247953,842,244 - 3,868,208 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Lasp1
1314 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:3995
Count of miRNA genes:835
Interacting mature miRNAs:1139
Transcripts:ENSMUST00000043843, ENSMUST00000107568, ENSMUST00000107569, ENSMUST00000127033, ENSMUST00000127575, ENSMUST00000129558, ENSMUST00000129828, ENSMUST00000134428, ENSMUST00000136723, ENSMUST00000138919, ENSMUST00000143571, ENSMUST00000146572, ENSMUST00000148280, ENSMUST00000152962, ENSMUST00000153520, ENSMUST00000155762
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
27226783Tibl5_mtibia length 5, 5 week (mouse)1168190826101890826Mouse
1302034Pkccl_mprotein kinase C content in lungs (mouse)Not determined1191604608121973369Mouse
1300628Lgth6_mbody length 6 (mouse)Not determined1166733420100733652Mouse
4141367Inf1_macute ozone induced inflammation (mouse)Not determined44630038113058009Mouse
1558812Rafar_mretinoic acid induced forelimb autopod reduction (mouse)Not determined1170691198104691366Mouse
1301535Pas5b_mpulmonary adenoma susceptibility 5b (mouse)Not determined1196176465108806384Mouse
1300766Skull16_mskull morphology 16 (mouse)Not determined1181574481115574636Mouse
1301404Sbmd4_mspinal bone mineral density 4 (mouse)Not determined1172019649106019734Mouse
12910539Sstapa3_msuseptibility to Staphylococcus aureus infection 3 (mouse)1196897693110603991Mouse
4142121Tmc1m2_mTmc1 modifier 2 (mouse)Not determined1156864027114157957Mouse
27226758Femd3_mfemur midshaft diameter 3, 5 week (mouse)1180890826101890826Mouse
14747003Mancz9_mmandible centroid size 9 (mouse)1185844911119844911Mouse
1301640Lore4_mloss of righting induced by ethanol 4 (mouse)Not determined1179156009107616472Mouse
10412288Carg4_mCandida albicans resistance gene 4 (mouse)Not determined1181810267115810267Mouse
11251723Ewc5_methanol withdrawal and consumption 5 (mouse)1189869251121973369Mouse
1301681Sle13_msystematic lupus erythematosus susceptibility 13 (mouse)Not determined1170691198104691366Mouse
1300784Prdt3_mprion disease incubation time 3 (mouse)Not determined1166733420100733652Mouse
4141339Nilac2_mnicotine induced locomotor activity 2 (mouse)Not determined1170691198104691366Mouse
10413882Moe1_mmodifier of epilepsy 1 (mouse)1177770978111771099Mouse
11039501Ltpr6a_mLeishmania tropica response 6a (mouse)116483033698830473Mouse
11039502Ltpr6b_mLeishmania tropica response 6b (mouse)116483033698830473Mouse
4141465Dbm2_mdiabetes modifier 2 (mouse)Not determined94437183118022724Mouse
10045617Heal26_mwound healing/regeneration 26 (mouse)Not determined1192939373112544554Mouse
10045616Heal25_mwound healing/regeneration 25 (mouse)Not determined1177437183111437322Mouse
1357631Motr1_mmodifier of tubby retinal degeneration 1 (mouse)Not determined1187691198103274115Mouse
1301310Tmevd5_mTheiler's murine encephalomyelitis virus induced demyelinating disease susceptibility 5 (mouse)Not determined1172726125106726289Mouse
1301153Estq3_mestradiol regulated response QTL 3 (mouse)Not determined119689769399327028Mouse
11039515Ltpr6_mLeishmania tropica response 6 (mouse)116483033698830473Mouse
4142348Pstc2_mperiosteal circumference 2 (mouse)Not determined1172818615106818733Mouse
1301414Heal10_mwound healing/regeneration 10 (mouse)Not determined1177437183111437322Mouse
1300651Pcyts3_mplasmacytoma susceptibility 3 (mouse)Not determined1170691198104691366Mouse
1301546Pcir2_mperiosteal circumference 2 (mouse)Not determined1166733420100733652Mouse
1300649Crhq1_mcompensatory renal hypertrophy QTL 1 (mouse)Not determined1181574481115574636Mouse
27226789Feml16_mfemur length 16, 10 week (mouse)1187490826121873369Mouse
14746970Manh71_mmandible shape 71 (mouse)1179416257113416257Mouse
10043865T2dm5sa_mtype 2 diabetes mellitus 5 in SMXA RI mice (mouse)Not determined1179813759104502698Mouse
39128214Lwq20_mliver weight QTL 20 (mouse)1112268637118022724Mouse
10043866Adip19_madiposity 19 (mouse)Not determined1172818615106818733Mouse
1301072Eae22_mexperimental allergic encephalomyelitis 22 (mouse)Not determined1182377698116377820Mouse
1300944Alcp20_malcohol preference locus 20 (mouse)Not determined1195403965121973369Mouse
4141939Pregq2_mpregnancy QTL 2 (mouse)Not determined1194063779118022724Mouse
11038695Par8_mpulmonary adenoma resistance 8 (mouse)1177063779111063918Mouse
1357766Si5lq6_mserum IGFBP-5 level QTL 6 (mouse)Not determined1166733420100733652Mouse
1301057Nidd4_mnon-insulin-dependent diabetes mellitus 4 (mouse)Not determined1196810136121973369Mouse
1301958Alcp18_malcohol preference locus 18 (mouse)Not determined1195403965121973369Mouse
1301833Tbbmd5_mtotal body bone mineral density 5 (mouse)Not determined1166733420100733652Mouse
1301491Abbp4_mA/J and C57BL/6 blood pressure 4 (mouse)Not determined118869958899081597Mouse
15014785Mvlq1_mmacrovesicular liver lesion QTL 1 (mouse)1186608320120608320Mouse
4141012Femwf6_mfemur work to failure 6 (mouse)Not determined66733420100733652Mouse
15039374Adip29_madiposity 29 (mouse)1186608320120608320Mouse
1300962Cd8mts4_mCD8 memory T cell subset 4 (mouse)Not determined1196137674121973369Mouse
1301095El6_mepilepsy 6 (mouse)Not determined1193229183121973369Mouse
27226731Tibmd4_mtibia midshaft diameter 4, 10 week (mouse)1194190826118890826Mouse
27226730Tibmd1_mtibia midshaft diameter 1, 5 week (mouse)1162590826109390826Mouse
15039376Bw42_mbody weight QTL 42 (mouse)1186608320120608320Mouse
1558753Ath19_matherosclerosis 19 (mouse)Not determined1191604608121973369Mouse
10044007Hbnr14_mHeligmosomoides bakeri nematode resistance 14 (mouse)Not determined1187502600121502698Mouse
1302124Eae7_msusceptibility to experimental allergic encephalomyelitis 7 (mouse)Not determined117757387399377820Mouse
13524529Bodwtq10_mbody wweight QTL 10 (mouse)119067951297699512Mouse

Markers in Region
RH136366  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm386117,997,744 - 117,997,939UniSTSGRCm38
MGSCv376117,947,762 - 117,947,957UniSTSGRCm37
Celera6119,818,973 - 119,819,168UniSTS
Cytogenetic Map11C-DUniSTS
Cytogenetic Map6F1UniSTS


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001433277 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_010688 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006532341 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006532342 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AK034404 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK049199 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK078445 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK148858 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK154656 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK168521 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK169381 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK179064 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK181281 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK185694 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK186907 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK190980 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK193804 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK195102 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK200217 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK202311 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK204591 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK205823 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK206302 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK208155 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK210691 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK212158 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK213374 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK213957 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK214011 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK214117 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK214597 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK216382 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK216407 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK216879 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK218727 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL596446 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AX327663 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC010840 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BE955478 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466556 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CT010288 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U58882 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X96702 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X96703 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X96973 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000043843   ⟹   ENSMUSP00000042123
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1197,690,391 - 97,729,590 (+)Ensembl
GRCm38.p6 Ensembl1197,799,565 - 97,838,764 (+)Ensembl
Ensembl Acc Id: ENSMUST00000107568
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1197,724,250 - 97,725,210 (+)Ensembl
GRCm38.p6 Ensembl1197,833,424 - 97,834,384 (+)Ensembl
Ensembl Acc Id: ENSMUST00000107569
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1197,690,498 - 97,698,145 (+)Ensembl
GRCm38.p6 Ensembl1197,799,672 - 97,807,319 (+)Ensembl
Ensembl Acc Id: ENSMUST00000127033   ⟹   ENSMUSP00000127792
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1197,692,824 - 97,715,736 (+)Ensembl
GRCm38.p6 Ensembl1197,801,998 - 97,824,910 (+)Ensembl
Ensembl Acc Id: ENSMUST00000127575
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1197,724,009 - 97,727,031 (+)Ensembl
GRCm38.p6 Ensembl1197,833,183 - 97,836,205 (+)Ensembl
Ensembl Acc Id: ENSMUST00000129558   ⟹   ENSMUSP00000123165
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1197,690,664 - 97,724,433 (+)Ensembl
GRCm38.p6 Ensembl1197,799,838 - 97,833,607 (+)Ensembl
Ensembl Acc Id: ENSMUST00000129828   ⟹   ENSMUSP00000115308
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1197,691,160 - 97,724,509 (+)Ensembl
GRCm38.p6 Ensembl1197,800,334 - 97,833,683 (+)Ensembl
Ensembl Acc Id: ENSMUST00000134428   ⟹   ENSMUSP00000119797
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1197,691,129 - 97,697,745 (+)Ensembl
GRCm38.p6 Ensembl1197,800,303 - 97,806,919 (+)Ensembl
Ensembl Acc Id: ENSMUST00000136723   ⟹   ENSMUSP00000114306
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1197,691,123 - 97,715,734 (+)Ensembl
GRCm38.p6 Ensembl1197,800,297 - 97,824,908 (+)Ensembl
Ensembl Acc Id: ENSMUST00000138919   ⟹   ENSMUSP00000114407
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1197,697,136 - 97,697,726 (+)Ensembl
GRCm38.p6 Ensembl1197,806,310 - 97,806,900 (+)Ensembl
Ensembl Acc Id: ENSMUST00000143571   ⟹   ENSMUSP00000116102
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1197,689,826 - 97,697,665 (+)Ensembl
GRCm38.p6 Ensembl1197,799,000 - 97,806,839 (+)Ensembl
Ensembl Acc Id: ENSMUST00000146572   ⟹   ENSMUSP00000121907
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1197,690,997 - 97,724,389 (+)Ensembl
GRCm38.p6 Ensembl1197,800,171 - 97,833,563 (+)Ensembl
Ensembl Acc Id: ENSMUST00000148280   ⟹   ENSMUSP00000123050
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1197,696,018 - 97,726,945 (+)Ensembl
GRCm38.p6 Ensembl1197,805,192 - 97,836,119 (+)Ensembl
Ensembl Acc Id: ENSMUST00000152962   ⟹   ENSMUSP00000120645
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1197,690,824 - 97,724,421 (+)Ensembl
GRCm38.p6 Ensembl1197,799,998 - 97,833,595 (+)Ensembl
Ensembl Acc Id: ENSMUST00000153520   ⟹   ENSMUSP00000120458
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1197,697,328 - 97,706,608 (+)Ensembl
GRCm38.p6 Ensembl1197,806,502 - 97,815,782 (+)Ensembl
Ensembl Acc Id: ENSMUST00000155762   ⟹   ENSMUSP00000119538
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1197,706,074 - 97,715,775 (+)Ensembl
GRCm38.p6 Ensembl1197,815,248 - 97,824,949 (+)Ensembl
RefSeq Acc Id: NM_010688   ⟹   NP_034818
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391197,690,391 - 97,729,591 (+)NCBI
GRCm381197,799,565 - 97,838,765 (+)NCBI
MGSCv371197,660,986 - 97,700,078 (+)RGD
Celera11107,449,132 - 107,487,995 (+)RGD
cM Map11 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006532341   ⟹   XP_006532404
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391197,689,748 - 97,729,591 (+)NCBI
GRCm381197,799,005 - 97,838,765 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006532342   ⟹   XP_006532405
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391197,692,829 - 97,729,591 (+)NCBI
GRCm381197,802,003 - 97,838,765 (+)NCBI
Sequence:
RefSeq Acc Id: NP_034818   ⟸   NM_010688
- UniProtKB: Q62416 (UniProtKB/Swiss-Prot),   Q61792 (UniProtKB/Swiss-Prot),   Q543N3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006532404   ⟸   XM_006532341
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_006532405   ⟸   XM_006532342
- Peptide Label: isoform X2
- UniProtKB: A2A6H0 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSMUSP00000114407   ⟸   ENSMUST00000138919
Ensembl Acc Id: ENSMUSP00000116102   ⟸   ENSMUST00000143571
Ensembl Acc Id: ENSMUSP00000120645   ⟸   ENSMUST00000152962
Ensembl Acc Id: ENSMUSP00000127792   ⟸   ENSMUST00000127033
Ensembl Acc Id: ENSMUSP00000121907   ⟸   ENSMUST00000146572
Ensembl Acc Id: ENSMUSP00000123165   ⟸   ENSMUST00000129558
Ensembl Acc Id: ENSMUSP00000115308   ⟸   ENSMUST00000129828
Ensembl Acc Id: ENSMUSP00000123050   ⟸   ENSMUST00000148280
Ensembl Acc Id: ENSMUSP00000119797   ⟸   ENSMUST00000134428
Ensembl Acc Id: ENSMUSP00000120458   ⟸   ENSMUST00000153520
Ensembl Acc Id: ENSMUSP00000042123   ⟸   ENSMUST00000043843
Ensembl Acc Id: ENSMUSP00000114306   ⟸   ENSMUST00000136723
Ensembl Acc Id: ENSMUSP00000119538   ⟸   ENSMUST00000155762
Protein Domains
LIM zinc-binding   SH3

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q61792-F1-model_v2 AlphaFold Q61792 1-263 view protein structure

Promoters
RGD ID:6821163
Promoter ID:MM_KWN:9521
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:ENSMUST00000107569,   ENSMUST00000107572,   OTTMUST00000005566,   OTTMUST00000005567,   OTTMUST00000005569,   OTTMUST00000005570,   OTTMUST00000005571,   OTTMUST00000005572,   OTTMUST00000005573,   OTTMUST00000005574,   OTTMUST00000005575
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361197,661,001 - 97,661,902 (+)MPROMDB
RGD ID:6846852
Promoter ID:MM_ACW:8782
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   Kidney,   MEF_B6
Transcripts:LASP1.NSEP07
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361197,663,051 - 97,663,551 (+)MPROMDB
RGD ID:6821164
Promoter ID:MM_KWN:9522
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   Kidney
Transcripts:OTTMUST00000005576
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361197,665,981 - 97,666,481 (+)MPROMDB
RGD ID:6821165
Promoter ID:MM_KWN:9524
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   Kidney,   Liver
Transcripts:OTTMUST00000005568,   OTTMUST00000005577
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361197,666,931 - 97,667,862 (+)MPROMDB
RGD ID:6821166
Promoter ID:MM_KWN:9525
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_4Hour,   MEF_B6,   Spleen
Transcripts:OTTMUST00000005578
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361197,676,151 - 97,677,052 (+)MPROMDB
RGD ID:8676450
Promoter ID:EPDNEW_M16250
Type:initiation region
Name:Lasp1_1
Description:Mus musculus LIM and SH3 protein 1 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381197,799,669 - 97,799,729EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:109656 AgrOrtholog
Ensembl Genes ENSMUSG00000038366 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000043843 ENTREZGENE
  ENSMUST00000043843.12 UniProtKB/Swiss-Prot
  ENSMUST00000127033.9 UniProtKB/TrEMBL
  ENSMUST00000129558.8 UniProtKB/TrEMBL
  ENSMUST00000129828.8 UniProtKB/TrEMBL
  ENSMUST00000134428.2 UniProtKB/TrEMBL
  ENSMUST00000136723.8 UniProtKB/TrEMBL
  ENSMUST00000138919.2 UniProtKB/TrEMBL
  ENSMUST00000143571.2 UniProtKB/TrEMBL
  ENSMUST00000146572.8 UniProtKB/TrEMBL
  ENSMUST00000148280 ENTREZGENE
  ENSMUST00000148280.3 UniProtKB/TrEMBL
  ENSMUST00000152962.8 UniProtKB/TrEMBL
  ENSMUST00000153520.3 UniProtKB/TrEMBL
  ENSMUST00000155762.3 UniProtKB/TrEMBL
Gene3D-CATH Cysteine Rich Protein UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3 Domains UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Lasp1_SH3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  LIM-SH3_domain_protein UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Nebulin_repeat UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3_domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Znf_LIM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:16796 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:109656 ENTREZGENE
NCBI Gene 16796 ENTREZGENE
PANTHER LASP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  LIM AND SH3 DOMAIN PROTEIN 1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam LIM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Nebulin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3_9 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Lasp1 PhenoGen
PRINTS SH3DOMAIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE LIM_DOMAIN_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  LIM_DOMAIN_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NEBULIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART LIM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NEBU UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SH3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP Glucocorticoid receptor-like (DNA-binding domain) UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF50044 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A2A6G0_MOUSE UniProtKB/TrEMBL
  A2A6G2_MOUSE UniProtKB/TrEMBL
  A2A6G3_MOUSE UniProtKB/TrEMBL
  A2A6G4_MOUSE UniProtKB/TrEMBL
  A2A6G5_MOUSE UniProtKB/TrEMBL
  A2A6G6_MOUSE UniProtKB/TrEMBL
  A2A6G7_MOUSE UniProtKB/TrEMBL
  A2A6G8_MOUSE UniProtKB/TrEMBL
  A2A6G9_MOUSE UniProtKB/TrEMBL
  A2A6H0 ENTREZGENE, UniProtKB/TrEMBL
  A2A6H1_MOUSE UniProtKB/TrEMBL
  E9Q0N6_MOUSE UniProtKB/TrEMBL
  LASP1_MOUSE UniProtKB/Swiss-Prot
  Q543N3 ENTREZGENE, UniProtKB/TrEMBL
  Q61792 ENTREZGENE
  Q62416 ENTREZGENE
UniProt Secondary Q62416 UniProtKB/Swiss-Prot