Epas1 Mouse (1->4)-beta-D-glucan multiple interactions EXP 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of EPAS1 mRNA CTD PMID:36331819 Epas1 Mouse 1,2-dimethylhydrazine decreases expression EXP 6480464 1 and 2-Dimethylhydrazine results in decreased expression of EPAS1 mRNA CTD PMID:22206623 Epas1 Mouse 1,2-dimethylhydrazine multiple interactions EXP 6480464 Folic Acid inhibits the reaction [1 and 2-Dimethylhydrazine results in decreased expression of EPAS1 mRNA] CTD PMID:22206623 Epas1 Mouse 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine multiple interactions EXP 6480464 [3 more ... CTD PMID:19679656 Epas1 Mouse 17alpha-ethynylestradiol increases expression ISO Epas1 (Rattus norvegicus) 6480464 Ethinyl Estradiol results in increased expression of EPAS1 mRNA CTD PMID:17351261 Epas1 Mouse 17beta-estradiol multiple interactions ISO EPAS1 (Homo sapiens) 6480464 [Estradiol co-treated with TGFB1 protein] results in decreased expression of EPAS1 mRNA and EGF protein inhibits the reaction [Estradiol results in decreased expression of EPAS1 mRNA] CTD PMID:24758408 and PMID:30165855 Epas1 Mouse 17beta-estradiol decreases expression ISO Epas1 (Rattus norvegicus) 6480464 Estradiol results in decreased expression of EPAS1 mRNA CTD PMID:32145629 Epas1 Mouse 17beta-estradiol multiple interactions EXP 6480464 [letrozole results in decreased abundance of Estradiol] which results in decreased expression of EPAS1 mRNA CTD PMID:19620711 Epas1 Mouse 17beta-estradiol decreases expression ISO EPAS1 (Homo sapiens) 6480464 Estradiol results in decreased expression of EPAS1 mRNA CTD PMID:24758408 more ... Epas1 Mouse 1H-benzimidazole increases stability ISO Epas1 (Rattus norvegicus) 6480464 benzimidazole results in increased stability of EPAS1 protein CTD PMID:23545307 Epas1 Mouse 2,3,7,8-tetrachlorodibenzodioxine affects expression EXP 6480464 Tetrachlorodibenzodioxin affects the expression of EPAS1 mRNA CTD PMID:16962184 more ... Epas1 Mouse 2,3,7,8-tetrachlorodibenzodioxine multiple interactions EXP 6480464 Tetrachlorodibenzodioxin promotes the reaction [AHR protein binds to EPAS1 gene] CTD PMID:28213091 Epas1 Mouse 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO Epas1 (Rattus norvegicus) 6480464 Tetrachlorodibenzodioxin affects the expression of EPAS1 mRNA CTD PMID:22298810 and PMID:34747641 Epas1 Mouse 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of EPAS1 mRNA CTD PMID:19933214 more ... Epas1 Mouse 2-amino-2-deoxy-D-glucopyranose decreases expression ISO Epas1 (Rattus norvegicus) 6480464 Glucosamine results in decreased expression of EPAS1 mRNA CTD PMID:17109745 Epas1 Mouse 2-amino-2-deoxy-D-glucopyranose multiple interactions ISO Epas1 (Rattus norvegicus) 6480464 Glucosamine inhibits the reaction [IL1B results in increased expression of EPAS1 mRNA] and IL1B affects the reaction [Glucosamine results in decreased expression of EPAS1 mRNA] CTD PMID:17109745 Epas1 Mouse 2-methylcholine affects expression ISO EPAS1 (Homo sapiens) 6480464 beta-methylcholine affects the expression of EPAS1 mRNA CTD PMID:21179406 Epas1 Mouse 2-palmitoylglycerol increases expression ISO EPAS1 (Homo sapiens) 6480464 2-palmitoylglycerol results in increased expression of EPAS1 mRNA CTD PMID:37199045 Epas1 Mouse 3,3',4,4',5-pentachlorobiphenyl decreases expression ISO Epas1 (Rattus norvegicus) 6480464 3 more ... CTD PMID:23196670 Epas1 Mouse 3,3',5-triiodo-L-thyronine increases expression EXP 6480464 Triiodothyronine results in increased expression of EPAS1 mRNA CTD PMID:25172293 Epas1 Mouse 3,4-dihydroxybenzoate multiple interactions EXP 6480464 [3 more ... CTD PMID:19679656 Epas1 Mouse 3,4-dihydroxybenzoate increases expression EXP 6480464 3 and 4-dihydroxybenzoate results in increased expression of EPAS1 mRNA CTD PMID:19679656 Epas1 Mouse 3-methylcholanthrene multiple interactions EXP 6480464 [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of EPAS1 mRNA CTD PMID:23519560 Epas1 Mouse 3-phenylprop-2-enal increases expression ISO EPAS1 (Homo sapiens) 6480464 cinnamaldehyde results in increased expression of EPAS1 mRNA CTD PMID:19524605 Epas1 Mouse 4,4'-diaminodiphenylmethane increases expression EXP 6480464 4 and 4'-diaminodiphenylmethane results in increased expression of EPAS1 mRNA CTD PMID:18648102 Epas1 Mouse 4,4'-sulfonyldiphenol increases expression EXP 6480464 bisphenol S results in increased expression of EPAS1 mRNA CTD PMID:30951980 Epas1 Mouse 4,4'-sulfonyldiphenol multiple interactions EXP 6480464 [bisphenol S co-treated with Tretinoin] results in decreased expression of EPAS1 mRNA CTD PMID:30951980 Epas1 Mouse 4-amino-2,6-dinitrotoluene affects expression ISO Epas1 (Rattus norvegicus) 6480464 4-amino-2 and 6-dinitrotoluene affects the expression of EPAS1 mRNA CTD PMID:21346803 Epas1 Mouse 4-hydroperoxycyclophosphamide increases expression EXP 6480464 perfosfamide results in increased expression of EPAS1 protein CTD PMID:23251655 Epas1 Mouse 4-hydroxy-TEMPO affects localization ISO EPAS1 (Homo sapiens) 6480464 tempol affects the localization of EPAS1 protein CTD PMID:24755467 Epas1 Mouse 5-fluorouracil increases expression ISO EPAS1 (Homo sapiens) 6480464 Fluorouracil results in increased expression of EPAS1 mRNA CTD PMID:16557594 Epas1 Mouse 6-propyl-2-thiouracil decreases expression ISO Epas1 (Rattus norvegicus) 6480464 Propylthiouracil results in decreased expression of EPAS1 mRNA CTD PMID:24780913 Epas1 Mouse acetaldehyde decreases expression ISO EPAS1 (Homo sapiens) 6480464 Acetaldehyde results in decreased expression of EPAS1 protein CTD PMID:35504338 Epas1 Mouse acetaldehyde multiple interactions ISO EPAS1 (Homo sapiens) 6480464 oxalylglycine inhibits the reaction [Acetaldehyde results in decreased expression of EPAS1 protein] and VH298 inhibits the reaction [Acetaldehyde results in decreased expression of EPAS1 protein] CTD PMID:35504338 Epas1 Mouse acetamide decreases expression ISO Epas1 (Rattus norvegicus) 6480464 acetamide results in decreased expression of EPAS1 mRNA CTD PMID:31881176 Epas1 Mouse actinomycin D increases stability ISO Epas1 (Rattus norvegicus) 6480464 Dactinomycin results in increased stability of EPAS1 protein CTD PMID:23545307 Epas1 Mouse aflatoxin B1 increases methylation ISO EPAS1 (Homo sapiens) 6480464 Aflatoxin B1 results in increased methylation of EPAS1 gene and Aflatoxin B1 results in increased methylation of EPAS1 intron CTD PMID:27153756 and PMID:30157460 Epas1 Mouse Aflatoxin B2 alpha increases methylation ISO EPAS1 (Homo sapiens) 6480464 aflatoxin B2 results in increased methylation of EPAS1 intron CTD PMID:30157460 Epas1 Mouse aldehydo-D-glucosamine decreases expression ISO Epas1 (Rattus norvegicus) 6480464 Glucosamine results in decreased expression of EPAS1 mRNA CTD PMID:17109745 Epas1 Mouse aldehydo-D-glucosamine multiple interactions ISO Epas1 (Rattus norvegicus) 6480464 Glucosamine inhibits the reaction [IL1B results in increased expression of EPAS1 mRNA] and IL1B affects the reaction [Glucosamine results in decreased expression of EPAS1 mRNA] CTD PMID:17109745 Epas1 Mouse all-trans-retinoic acid increases expression ISO EPAS1 (Homo sapiens) 6480464 Tretinoin results in increased expression of EPAS1 mRNA CTD PMID:15894607 more ... Epas1 Mouse all-trans-retinoic acid multiple interactions EXP 6480464 [bisphenol S co-treated with Tretinoin] results in decreased expression of EPAS1 mRNA CTD PMID:30951980 Epas1 Mouse alpha-Zearalanol multiple interactions ISO Epas1 (Rattus norvegicus) 6480464 [Zeranol co-treated with perfluorooctanoic acid] results in increased expression of EPAS1 mRNA CTD PMID:35163327 Epas1 Mouse ammonium chloride affects expression ISO Epas1 (Rattus norvegicus) 6480464 Ammonium Chloride affects the expression of EPAS1 mRNA CTD PMID:16483693 Epas1 Mouse ammonium chloride increases expression ISO EPAS1 (Homo sapiens) 6480464 Ammonium Chloride results in increased expression of EPAS1 protein CTD PMID:35504338 Epas1 Mouse ammonium chloride multiple interactions ISO EPAS1 (Homo sapiens) 6480464 Formaldehyde inhibits the reaction [Ammonium Chloride results in increased expression of EPAS1 protein] CTD PMID:35504338 Epas1 Mouse antimycin A multiple interactions ISO Epas1 (Rattus norvegicus) 6480464 Antimycin A inhibits the reaction [Oxygen deficiency results in increased expression of EPAS1 protein] CTD PMID:18353899 Epas1 Mouse aristolochic acid A increases expression ISO EPAS1 (Homo sapiens) 6480464 aristolochic acid I results in increased expression of EPAS1 protein CTD PMID:21554934 Epas1 Mouse aristolochic acid A decreases expression ISO EPAS1 (Homo sapiens) 6480464 aristolochic acid I results in decreased expression of EPAS1 mRNA CTD PMID:33212167 Epas1 Mouse arsenite(3-) increases expression ISO EPAS1 (Homo sapiens) 6480464 arsenite results in increased expression of EPAS1 protein CTD PMID:22447124 Epas1 Mouse arsenite(3-) multiple interactions ISO EPAS1 (Homo sapiens) 6480464 arsenite inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of EPAS1 protein] more ... CTD PMID:22447124 Epas1 Mouse atrazine decreases expression ISO EPAS1 (Homo sapiens) 6480464 Atrazine results in decreased expression of EPAS1 mRNA CTD PMID:22378314 Epas1 Mouse benzo[a]pyrene decreases expression EXP 6480464 Benzo(a)pyrene results in decreased expression of EPAS1 mRNA CTD PMID:19770486 and PMID:22228805 Epas1 Mouse benzo[a]pyrene decreases expression ISO EPAS1 (Homo sapiens) 6480464 Benzo(a)pyrene results in decreased expression of EPAS1 mRNA CTD PMID:30453624 Epas1 Mouse benzo[a]pyrene increases methylation EXP 6480464 Benzo(a)pyrene results in increased methylation of EPAS1 intron CTD PMID:27901495 Epas1 Mouse benzo[a]pyrene increases expression EXP 6480464 Benzo(a)pyrene results in increased expression of EPAS1 mRNA CTD PMID:22228805 and PMID:23735875 Epas1 Mouse benzo[a]pyrene affects response to substance ISO EPAS1 (Homo sapiens) 6480464 EPAS1 protein affects the susceptibility to Benzo(a)pyrene CTD PMID:23333640 Epas1 Mouse benzo[a]pyrene diol epoxide I increases expression ISO EPAS1 (Homo sapiens) 6480464 7 more ... CTD PMID:20382639 Epas1 Mouse benzo[a]pyrene diol epoxide I decreases expression ISO EPAS1 (Homo sapiens) 6480464 7 more ... CTD PMID:19150397 Epas1 Mouse beta-D-glucosamine decreases expression ISO Epas1 (Rattus norvegicus) 6480464 Glucosamine results in decreased expression of EPAS1 mRNA CTD PMID:17109745 Epas1 Mouse beta-D-glucosamine multiple interactions ISO Epas1 (Rattus norvegicus) 6480464 Glucosamine inhibits the reaction [IL1B results in increased expression of EPAS1 mRNA] and IL1B affects the reaction [Glucosamine results in decreased expression of EPAS1 mRNA] CTD PMID:17109745 Epas1 Mouse bis(2-chloroethyl) sulfide increases expression EXP 6480464 Mustard Gas results in increased expression of EPAS1 mRNA CTD PMID:15674843 Epas1 Mouse bis(2-ethylhexyl) phthalate increases expression ISO EPAS1 (Homo sapiens) 6480464 Diethylhexyl Phthalate results in increased expression of EPAS1 mRNA CTD PMID:31163220 Epas1 Mouse bisphenol A increases expression ISO Epas1 (Rattus norvegicus) 6480464 bisphenol A results in increased expression of EPAS1 mRNA CTD PMID:25181051 Epas1 Mouse bisphenol A multiple interactions ISO EPAS1 (Homo sapiens) 6480464 [bisphenol A co-treated with Fulvestrant] results in decreased methylation of EPAS1 gene CTD PMID:31601247 Epas1 Mouse bisphenol A decreases methylation ISO EPAS1 (Homo sapiens) 6480464 bisphenol A results in decreased methylation of EPAS1 gene CTD PMID:31601247 Epas1 Mouse bisphenol A affects expression ISO Epas1 (Rattus norvegicus) 6480464 bisphenol A affects the expression of EPAS1 mRNA CTD PMID:32145629 Epas1 Mouse bisphenol A decreases expression ISO Epas1 (Rattus norvegicus) 6480464 bisphenol A results in decreased expression of EPAS1 mRNA CTD PMID:30816183 Epas1 Mouse bisphenol A affects expression ISO EPAS1 (Homo sapiens) 6480464 bisphenol A affects the expression of EPAS1 mRNA CTD PMID:30903817 Epas1 Mouse bisphenol A increases expression ISO EPAS1 (Homo sapiens) 6480464 bisphenol A results in increased expression of EPAS1 mRNA CTD PMID:29275510 Epas1 Mouse bisphenol A increases methylation ISO Epas1 (Rattus norvegicus) 6480464 bisphenol A results in increased methylation of EPAS1 gene CTD PMID:28505145 Epas1 Mouse bisphenol A decreases expression ISO EPAS1 (Homo sapiens) 6480464 bisphenol A results in decreased expression of EPAS1 mRNA CTD PMID:28711546 Epas1 Mouse Bisphenol B decreases expression ISO EPAS1 (Homo sapiens) 6480464 bisphenol B results in decreased expression of EPAS1 mRNA CTD PMID:28591870 Epas1 Mouse bisphenol F decreases expression ISO EPAS1 (Homo sapiens) 6480464 bisphenol F results in decreased expression of EPAS1 mRNA CTD PMID:28591870 Epas1 Mouse bisphenol F increases expression EXP 6480464 bisphenol F results in increased expression of EPAS1 mRNA CTD PMID:38685157 Epas1 Mouse butan-1-ol multiple interactions ISO EPAS1 (Homo sapiens) 6480464 [[Gasoline co-treated with 1-Butanol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in increased expression of EPAS1 mRNA CTD PMID:29432896 Epas1 Mouse cadmium atom multiple interactions ISO EPAS1 (Homo sapiens) 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which affects the folding of EPAS1 protein and [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of EPAS1 protein CTD PMID:35504338 Epas1 Mouse cadmium atom multiple interactions EXP 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of EPAS1 mRNA CTD PMID:37325564 Epas1 Mouse cadmium dichloride increases methylation ISO Epas1 (Rattus norvegicus) 6480464 Cadmium Chloride results in increased methylation of EPAS1 promoter CTD PMID:22457795 Epas1 Mouse cadmium dichloride multiple interactions EXP 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of EPAS1 mRNA CTD PMID:37325564 Epas1 Mouse cadmium dichloride multiple interactions ISO EPAS1 (Homo sapiens) 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which affects the folding of EPAS1 protein and [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of EPAS1 protein CTD PMID:35504338 Epas1 Mouse cadmium dichloride decreases expression ISO EPAS1 (Homo sapiens) 6480464 Cadmium Chloride results in decreased expression of EPAS1 mRNA CTD PMID:38568856 Epas1 Mouse cannabidiol decreases methylation EXP 6480464 Cannabidiol results in decreased methylation of EPAS1 gene CTD PMID:33407853 Epas1 Mouse carbon nanotube decreases expression EXP 6480464 Nanotubes more ... CTD PMID:25554681 Epas1 Mouse chloropicrin affects expression ISO EPAS1 (Homo sapiens) 6480464 chloropicrin affects the expression of EPAS1 mRNA CTD PMID:26352163 Epas1 Mouse chlorpyrifos decreases expression ISO Epas1 (Rattus norvegicus) 6480464 Chlorpyrifos results in decreased expression of EPAS1 mRNA CTD PMID:18668222 Epas1 Mouse choline multiple interactions EXP 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of EPAS1 mRNA and [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of EPAS1 gene CTD PMID:20938992 Epas1 Mouse chromium(6+) affects expression EXP 6480464 chromium hexavalent ion affects the expression of EPAS1 mRNA CTD PMID:28472532 Epas1 Mouse ciglitazone multiple interactions ISO EPAS1 (Homo sapiens) 6480464 [ciglitazone binds to PPARG protein] which results in increased expression of EPAS1 mRNA CTD PMID:16197558 Epas1 Mouse clofibrate decreases expression EXP 6480464 Clofibrate results in decreased expression of EPAS1 mRNA CTD PMID:23811191 Epas1 Mouse cobalt atom multiple interactions EXP 6480464 EPAS1 protein affects the reaction [Cobalt results in increased abundance of Nitric Oxide] CTD PMID:23788631 Epas1 Mouse cobalt atom increases expression ISO Epas1 (Rattus norvegicus) 6480464 Cobalt results in increased expression of EPAS1 protein CTD PMID:17967803 Epas1 Mouse cobalt dichloride increases expression ISO Epas1 (Rattus norvegicus) 6480464 cobaltous chloride results in increased expression of EPAS1 protein CTD PMID:21558026 and PMID:23545307 Epas1 Mouse cobalt dichloride increases expression EXP 6480464 cobaltous chloride results in increased expression of EPAS1 protein CTD PMID:24503013 Epas1 Mouse cobalt dichloride increases stability ISO EPAS1 (Homo sapiens) 6480464 cobaltous chloride results in increased stability of EPAS1 protein CTD PMID:18515279 Epas1 Mouse cobalt dichloride increases expression ISO EPAS1 (Homo sapiens) 6480464 cobaltous chloride results in increased expression of EPAS1 protein CTD PMID:21036805 more ... Epas1 Mouse cobalt dichloride affects localization ISO EPAS1 (Homo sapiens) 6480464 cobaltous chloride affects the localization of EPAS1 protein CTD PMID:21863063 Epas1 Mouse cobalt dichloride increases response to substance ISO EPAS1 (Homo sapiens) 6480464 EPAS1 protein results in increased susceptibility to cobaltous chloride CTD PMID:25805230 Epas1 Mouse cobalt dichloride multiple interactions ISO Epas1 (Rattus norvegicus) 6480464 [AQP1 protein results in increased stability of EPAS1 protein] promotes the reaction [cobaltous chloride results in increased expression of EPAS1 protein] more ... CTD PMID:23545307 Epas1 Mouse cobalt dichloride multiple interactions ISO EPAS1 (Homo sapiens) 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [cobaltous chloride results in increased expression of EPAS1 protein] more ... CTD PMID:21863063 more ... Epas1 Mouse copper atom multiple interactions EXP 6480464 EPAS1 gene mutant form inhibits the reaction [Copper deficiency results in increased expression of CYBRD1 mRNA] more ... CTD PMID:23555700 Epas1 Mouse copper atom multiple interactions ISO EPAS1 (Homo sapiens) 6480464 [Chelating Agents binds to Copper] which results in increased expression of EPAS1 mRNA CTD PMID:30911355 Epas1 Mouse copper atom increases expression ISO Epas1 (Rattus norvegicus) 6480464 Copper results in increased expression of EPAS1 mRNA CTD PMID:30556269 Epas1 Mouse copper atom increases expression EXP 6480464 Copper deficiency results in increased expression of EPAS1 protein CTD PMID:23555700 Epas1 Mouse copper(0) multiple interactions EXP 6480464 EPAS1 gene mutant form inhibits the reaction [Copper deficiency results in increased expression of CYBRD1 mRNA] more ... CTD PMID:23555700 Epas1 Mouse copper(0) multiple interactions ISO EPAS1 (Homo sapiens) 6480464 [Chelating Agents binds to Copper] which results in increased expression of EPAS1 mRNA CTD PMID:30911355 Epas1 Mouse copper(0) increases expression ISO Epas1 (Rattus norvegicus) 6480464 Copper results in increased expression of EPAS1 mRNA CTD PMID:30556269 Epas1 Mouse copper(0) increases expression EXP 6480464 Copper deficiency results in increased expression of EPAS1 protein CTD PMID:23555700 Epas1 Mouse copper(II) sulfate increases expression ISO EPAS1 (Homo sapiens) 6480464 Copper Sulfate results in increased expression of EPAS1 mRNA CTD PMID:19549813 Epas1 Mouse crocidolite asbestos increases expression ISO EPAS1 (Homo sapiens) 6480464 Asbestos and Crocidolite results in increased expression of EPAS1 mRNA CTD PMID:18687144 Epas1 Mouse curcumin multiple interactions ISO EPAS1 (Homo sapiens) 6480464 Curcumin analog inhibits the reaction [Oxygen deficiency results in increased expression of EPAS1 protein] CTD PMID:20554536 Epas1 Mouse cycloheximide multiple interactions ISO EPAS1 (Homo sapiens) 6480464 Cycloheximide inhibits the reaction [cobaltous chloride results in increased expression of EPAS1 protein] more ... CTD PMID:23958427 and PMID:26735578 Epas1 Mouse cycloheximide decreases expression ISO EPAS1 (Homo sapiens) 6480464 Cycloheximide results in decreased expression of EPAS1 protein CTD PMID:26735578 Epas1 Mouse cyclosporin A decreases expression ISO EPAS1 (Homo sapiens) 6480464 Cyclosporine results in decreased expression of EPAS1 mRNA CTD PMID:20106945 and PMID:27989131 Epas1 Mouse cyclosporin A increases expression ISO EPAS1 (Homo sapiens) 6480464 Cyclosporine results in increased expression of EPAS1 mRNA CTD PMID:25562108 Epas1 Mouse cyclosporin A decreases expression EXP 6480464 Cyclosporine results in decreased expression of EPAS1 mRNA CTD PMID:19770486 Epas1 Mouse DDT decreases expression ISO Epas1 (Rattus norvegicus) 6480464 DDT results in decreased expression of EPAS1 mRNA CTD PMID:30207508 Epas1 Mouse deguelin decreases expression ISO EPAS1 (Homo sapiens) 6480464 deguelin results in decreased expression of EPAS1 protein CTD PMID:19336726 Epas1 Mouse delphinidin multiple interactions ISO EPAS1 (Homo sapiens) 6480464 delphinidin inhibits the reaction [Hydrogen Peroxide results in increased expression of EPAS1 protein] CTD PMID:18603805 Epas1 Mouse desferrioxamine B multiple interactions ISO EPAS1 (Homo sapiens) 6480464 Deferoxamine inhibits the reaction [EPAS1 protein results in increased degradation of COX4I1 protein] CTD PMID:18515279 Epas1 Mouse desferrioxamine B increases expression ISO EPAS1 (Homo sapiens) 6480464 Deferoxamine results in increased expression of EPAS1 protein CTD PMID:22447124 more ... Epas1 Mouse desferrioxamine B increases expression ISO Epas1 (Rattus norvegicus) 6480464 Deferoxamine results in increased expression of EPAS1 protein CTD PMID:18353899 and PMID:21558026 Epas1 Mouse desferrioxamine B increases stability ISO EPAS1 (Homo sapiens) 6480464 Deferoxamine results in increased stability of EPAS1 protein CTD PMID:18515279 Epas1 Mouse diazinon increases methylation ISO EPAS1 (Homo sapiens) 6480464 Diazinon results in increased methylation of EPAS1 gene CTD PMID:22964155 Epas1 Mouse Dibutyl phosphate affects expression ISO EPAS1 (Homo sapiens) 6480464 di-n-butylphosphoric acid affects the expression of EPAS1 mRNA CTD PMID:37042841 Epas1 Mouse diclofenac decreases expression ISO EPAS1 (Homo sapiens) 6480464 Diclofenac results in decreased expression of EPAS1 protein CTD PMID:12912967 Epas1 Mouse dicrotophos increases expression ISO EPAS1 (Homo sapiens) 6480464 dicrotophos results in increased expression of EPAS1 mRNA CTD PMID:28302478 Epas1 Mouse diethyl malate affects expression EXP 6480464 diethyl malate affects the expression of EPAS1 mRNA CTD PMID:24814887 Epas1 Mouse diethylstilbestrol increases expression ISO Epas1 (Rattus norvegicus) 6480464 Diethylstilbestrol results in increased expression of EPAS1 mRNA CTD PMID:37077353 Epas1 Mouse diisononyl phthalate decreases expression EXP 6480464 diisononyl phthalate results in decreased expression of EPAS1 mRNA CTD PMID:37482143 Epas1 Mouse dinophysistoxin 1 increases expression ISO EPAS1 (Homo sapiens) 6480464 dinophysistoxin 1 results in increased expression of EPAS1 mRNA CTD PMID:28939011 Epas1 Mouse dioxygen multiple interactions ISO EPAS1 (Homo sapiens) 6480464 1-cyclopropyl-4-(4-((5-methyl-3-(3-(4-(trifluoromethoxy)phenyl)-1 more ... CTD PMID:20046830 more ... Epas1 Mouse dioxygen increases expression EXP 6480464 Oxygen deficiency results in increased expression of EPAS1 protein CTD PMID:24503013 and PMID:26723917 Epas1 Mouse dioxygen increases expression ISO Epas1 (Rattus norvegicus) 6480464 Oxygen deficiency results in increased expression of EPAS1 protein CTD PMID:18353899 and PMID:23545307 Epas1 Mouse dioxygen affects localization ISO EPAS1 (Homo sapiens) 6480464 Oxygen deficiency affects the localization of EPAS1 protein CTD PMID:24755467 Epas1 Mouse dioxygen increases expression ISO EPAS1 (Homo sapiens) 6480464 Oxygen deficiency results in increased expression of EPAS1 mRNA and Oxygen deficiency results in increased expression of EPAS1 protein CTD PMID:20554536 more ... Epas1 Mouse dioxygen multiple interactions EXP 6480464 Oxygen deficiency affects the localization of and results in increased activity of EPAS1 protein CTD PMID:20880076 Epas1 Mouse dioxygen affects response to substance ISO Epas1 (Rattus norvegicus) 6480464 EPAS1 protein affects the susceptibility to Oxygen deficiency CTD PMID:12679337 Epas1 Mouse dioxygen multiple interactions ISO Epas1 (Rattus norvegicus) 6480464 [AQP1 protein results in increased stability of EPAS1 protein] promotes the reaction [Oxygen deficiency results in increased expression of EPAS1 protein] more ... CTD PMID:12679337 more ... Epas1 Mouse disodium selenite increases expression ISO EPAS1 (Homo sapiens) 6480464 Sodium Selenite results in increased expression of EPAS1 mRNA CTD PMID:24383545 Epas1 Mouse dorsomorphin multiple interactions ISO EPAS1 (Homo sapiens) 6480464 [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 Epas1 Mouse doxorubicin decreases expression EXP 6480464 Doxorubicin results in decreased expression of EPAS1 mRNA CTD PMID:26873546 Epas1 Mouse doxorubicin decreases expression ISO EPAS1 (Homo sapiens) 6480464 Doxorubicin results in decreased expression of EPAS1 mRNA CTD PMID:29803840 Epas1 Mouse epoxiconazole decreases expression EXP 6480464 epoxiconazole results in decreased expression of EPAS1 mRNA CTD PMID:35436446 Epas1 Mouse ethanol multiple interactions ISO EPAS1 (Homo sapiens) 6480464 [[Gasoline co-treated with Ethanol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in increased expression of EPAS1 mRNA CTD PMID:29432896 Epas1 Mouse ethanol affects splicing EXP 6480464 Ethanol affects the splicing of EPAS1 mRNA CTD PMID:30319688 Epas1 Mouse ethanol increases expression EXP 6480464 Ethanol results in increased expression of EPAS1 mRNA CTD PMID:30319688 Epas1 Mouse fenamidone increases expression EXP 6480464 fenamidone results in increased expression of EPAS1 mRNA CTD PMID:27029645 Epas1 Mouse flutamide increases expression ISO Epas1 (Rattus norvegicus) 6480464 Flutamide results in increased expression of EPAS1 mRNA CTD PMID:24136188 Epas1 Mouse folic acid multiple interactions EXP 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of EPAS1 mRNA more ... CTD PMID:20938992 and PMID:22206623 Epas1 Mouse formaldehyde multiple interactions ISO EPAS1 (Homo sapiens) 6480464 [Formaldehyde co-treated with pevonedistat co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] affects the folding of EPAS1 protein more ... CTD PMID:35504338 Epas1 Mouse formaldehyde decreases expression ISO EPAS1 (Homo sapiens) 6480464 Formaldehyde results in decreased expression of EPAS1 protein CTD PMID:35504338 Epas1 Mouse fulvestrant multiple interactions ISO EPAS1 (Homo sapiens) 6480464 [bisphenol A co-treated with Fulvestrant] results in decreased methylation of EPAS1 gene CTD PMID:31601247 Epas1 Mouse furan increases expression EXP 6480464 furan results in increased expression of EPAS1 mRNA CTD PMID:24183702 Epas1 Mouse galangin multiple interactions ISO EPAS1 (Homo sapiens) 6480464 ferrous sulfate inhibits the reaction [galangin results in increased expression of EPAS1 protein] and Iron inhibits the reaction [galangin results in increased expression of EPAS1 protein] CTD PMID:17973296 Epas1 Mouse galangin increases expression ISO EPAS1 (Homo sapiens) 6480464 galangin results in increased expression of EPAS1 protein CTD PMID:17973296 Epas1 Mouse glutathione multiple interactions ISO EPAS1 (Homo sapiens) 6480464 Glutathione inhibits the reaction [cobaltous chloride results in increased expression of EPAS1 protein] and Glutathione inhibits the reaction [Oxygen deficiency results in increased expression of EPAS1 protein] CTD PMID:23958427 Epas1 Mouse hydralazine multiple interactions ISO EPAS1 (Homo sapiens) 6480464 [Hydralazine co-treated with Valproic Acid] results in increased expression of EPAS1 mRNA CTD PMID:17183730 Epas1 Mouse hydrogen peroxide multiple interactions ISO EPAS1 (Homo sapiens) 6480464 delphinidin inhibits the reaction [Hydrogen Peroxide results in increased expression of EPAS1 protein] CTD PMID:18603805 Epas1 Mouse hydrogen peroxide increases expression ISO EPAS1 (Homo sapiens) 6480464 Hydrogen Peroxide results in increased expression of EPAS1 mRNA and Hydrogen Peroxide results in increased expression of EPAS1 protein CTD PMID:18603805 and PMID:34581912 Epas1 Mouse hydrogen peroxide affects expression ISO EPAS1 (Homo sapiens) 6480464 Hydrogen Peroxide affects the expression of EPAS1 mRNA CTD PMID:20044591 Epas1 Mouse ibuprofen decreases expression ISO EPAS1 (Homo sapiens) 6480464 Ibuprofen results in decreased expression of EPAS1 protein CTD PMID:12912967 Epas1 Mouse indoxyl sulfate multiple interactions ISO EPAS1 (Homo sapiens) 6480464 Indican inhibits the reaction [cobaltous chloride affects the localization of EPAS1 protein] CTD PMID:21863063 Epas1 Mouse iron atom multiple interactions ISO EPAS1 (Homo sapiens) 6480464 Iron inhibits the reaction [galangin results in increased expression of EPAS1 protein] and Iron inhibits the reaction [Quercetin results in increased expression of EPAS1 protein] CTD PMID:17973296 Epas1 Mouse iron atom increases expression ISO Epas1 (Rattus norvegicus) 6480464 Iron deficiency results in increased expression of EPAS1 protein CTD PMID:23814049 Epas1 Mouse iron(0) multiple interactions ISO EPAS1 (Homo sapiens) 6480464 Iron inhibits the reaction [galangin results in increased expression of EPAS1 protein] and Iron inhibits the reaction [Quercetin results in increased expression of EPAS1 protein] CTD PMID:17973296 Epas1 Mouse iron(0) increases expression ISO Epas1 (Rattus norvegicus) 6480464 Iron deficiency results in increased expression of EPAS1 protein CTD PMID:23814049 Epas1 Mouse iron(2+) sulfate (anhydrous) multiple interactions ISO EPAS1 (Homo sapiens) 6480464 ferrous sulfate inhibits the reaction [galangin results in increased expression of EPAS1 protein] and ferrous sulfate inhibits the reaction [Quercetin results in increased expression of EPAS1 protein] CTD PMID:17973296 Epas1 Mouse ketoconazole increases expression ISO Epas1 (Rattus norvegicus) 6480464 Ketoconazole results in increased expression of EPAS1 mRNA CTD PMID:37077353 Epas1 Mouse ketoconazole increases expression ISO EPAS1 (Homo sapiens) 6480464 Ketoconazole results in increased expression of EPAS1 mRNA CTD PMID:36621641 Epas1 Mouse ketorolac decreases expression ISO EPAS1 (Homo sapiens) 6480464 Ketorolac results in decreased expression of EPAS1 protein CTD PMID:12912967 Epas1 Mouse L-ascorbic acid multiple interactions ISO EPAS1 (Homo sapiens) 6480464 Ascorbic Acid inhibits the reaction [nickel sulfate results in increased expression of EPAS1 protein] CTD PMID:16288478 Epas1 Mouse L-methionine multiple interactions EXP 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of EPAS1 mRNA and [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of EPAS1 gene CTD PMID:20938992 Epas1 Mouse leflunomide increases expression ISO EPAS1 (Homo sapiens) 6480464 leflunomide results in increased expression of EPAS1 mRNA CTD PMID:28988120 Epas1 Mouse letrozole multiple interactions EXP 6480464 [letrozole results in decreased abundance of Estradiol] which results in decreased expression of EPAS1 mRNA CTD PMID:19620711 Epas1 Mouse LY294002 multiple interactions ISO EPAS1 (Homo sapiens) 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [cobaltous chloride results in increased expression of EPAS1 protein] and 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Oxygen deficiency results in increased expression of EPAS1 protein] CTD PMID:23958427 Epas1 Mouse manganese(II) chloride increases expression EXP 6480464 manganese chloride results in increased expression of EPAS1 mRNA CTD PMID:17467022 Epas1 Mouse menadione affects expression ISO EPAS1 (Homo sapiens) 6480464 Vitamin K 3 affects the expression of EPAS1 mRNA CTD PMID:20044591 Epas1 Mouse mercury dibromide increases expression ISO EPAS1 (Homo sapiens) 6480464 mercuric bromide results in increased expression of EPAS1 mRNA CTD PMID:26272509 Epas1 Mouse mercury dibromide multiple interactions ISO EPAS1 (Homo sapiens) 6480464 [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of EPAS1 mRNA CTD PMID:27188386 Epas1 Mouse methamphetamine increases expression ISO Epas1 (Rattus norvegicus) 6480464 Methamphetamine results in increased expression of EPAS1 mRNA CTD PMID:32035215 Epas1 Mouse methotrexate increases expression ISO EPAS1 (Homo sapiens) 6480464 Methotrexate results in increased expression of EPAS1 mRNA CTD PMID:17400583 Epas1 Mouse methoxychlor affects methylation ISO Epas1 (Rattus norvegicus) 6480464 Methoxychlor affects the methylation of EPAS1 gene CTD PMID:35440735 Epas1 Mouse methyl methanesulfonate increases expression ISO EPAS1 (Homo sapiens) 6480464 Methyl Methanesulfonate results in increased expression of EPAS1 mRNA CTD PMID:23649840 Epas1 Mouse mithramycin decreases expression ISO Epas1 (Rattus norvegicus) 6480464 Plicamycin results in decreased expression of EPAS1 mRNA CTD PMID:23814049 Epas1 Mouse molibresib increases expression ISO EPAS1 (Homo sapiens) 6480464 molibresib results in increased expression of EPAS1 mRNA CTD PMID:27292261 Epas1 Mouse molibresib multiple interactions ISO EPAS1 (Homo sapiens) 6480464 [Oxygen deficiency co-treated with molibresib] results in increased expression of EPAS1 mRNA CTD PMID:27292261 Epas1 Mouse myxothiazol multiple interactions ISO Epas1 (Rattus norvegicus) 6480464 myxothiazol inhibits the reaction [Oxygen deficiency results in increased expression of EPAS1 protein] CTD PMID:18353899 Epas1 Mouse N-acetyl-L-cysteine multiple interactions ISO EPAS1 (Homo sapiens) 6480464 Acetylcysteine inhibits the reaction [cobaltous chloride results in increased expression of EPAS1 protein] and Acetylcysteine inhibits the reaction [Oxygen deficiency results in increased expression of EPAS1 protein] CTD PMID:23958427 Epas1 Mouse N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal multiple interactions ISO Epas1 (Rattus norvegicus) 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Oxygen inhibits the reaction [AQP3 protein results in increased stability of EPAS1 protein]] and benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Oxygen inhibits the reaction [AQP5 protein results in increased stability of EPAS1 protein]] CTD PMID:23545307 Epas1 Mouse N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal increases ubiquitination ISO EPAS1 (Homo sapiens) 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased ubiquitination of EPAS1 protein CTD PMID:22447124 Epas1 Mouse N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal increases expression ISO EPAS1 (Homo sapiens) 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of EPAS1 protein CTD PMID:35504338 Epas1 Mouse N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal multiple interactions ISO EPAS1 (Homo sapiens) 6480464 [Formaldehyde co-treated with pevonedistat co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] affects the folding of EPAS1 protein more ... CTD PMID:22447124 more ... Epas1 Mouse N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal increases hydroxylation ISO EPAS1 (Homo sapiens) 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased hydroxylation of EPAS1 protein CTD PMID:26735578 Epas1 Mouse N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal increases stability ISO Epas1 (Rattus norvegicus) 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased stability of EPAS1 protein CTD PMID:23545307 Epas1 Mouse N-methyl-4-phenylpyridinium decreases expression ISO EPAS1 (Homo sapiens) 6480464 1-Methyl-4-phenylpyridinium results in decreased expression of EPAS1 mRNA CTD PMID:25234470 Epas1 Mouse N-methyl-4-phenylpyridinium increases expression ISO EPAS1 (Homo sapiens) 6480464 1-Methyl-4-phenylpyridinium results in increased expression of EPAS1 mRNA CTD PMID:25234470 Epas1 Mouse nickel atom multiple interactions EXP 6480464 EPAS1 protein affects the reaction [Nickel results in increased abundance of Nitric Oxide] CTD PMID:23788631 Epas1 Mouse nickel sulfate increases stability ISO EPAS1 (Homo sapiens) 6480464 nickel sulfate results in increased stability of EPAS1 protein CTD PMID:20046830 Epas1 Mouse nickel sulfate multiple interactions ISO EPAS1 (Homo sapiens) 6480464 [HIF1A mRNA co-treated with EPAS1 mRNA] affects the reaction [nickel sulfate results in decreased expression of USP28 protein] more ... CTD PMID:16288478 and PMID:20046830 Epas1 Mouse nickel sulfate increases expression ISO EPAS1 (Homo sapiens) 6480464 nickel sulfate results in increased expression of EPAS1 mRNA and nickel sulfate results in increased expression of EPAS1 protein CTD PMID:16288478 and PMID:22714537 Epas1 Mouse niclosamide multiple interactions ISO EPAS1 (Homo sapiens) 6480464 Niclosamide inhibits the reaction [Oxygen deficiency results in increased expression of EPAS1 protein] CTD PMID:36318118 Epas1 Mouse nitric oxide multiple interactions EXP 6480464 EPAS1 protein affects the reaction [Cobalt results in increased abundance of Nitric Oxide] and EPAS1 protein affects the reaction [Nickel results in increased abundance of Nitric Oxide] CTD PMID:23788631 Epas1 Mouse nitrofen decreases expression ISO Epas1 (Rattus norvegicus) 6480464 nitrofen results in decreased expression of EPAS1 mRNA CTD PMID:20638522 Epas1 Mouse Nor-9-carboxy-delta9-THC multiple interactions ISO EPAS1 (Homo sapiens) 6480464 [Cannabinoids results in increased abundance of 11-nor-delta(9)-tetrahydrocannabinol-9-carboxylic acid] which affects the methylation of EPAS1 gene CTD PMID:30521419 Epas1 Mouse ochratoxin A multiple interactions ISO EPAS1 (Homo sapiens) 6480464 EPAS1 protein inhibits the reaction [ochratoxin A results in decreased expression of VEGFA protein] CTD PMID:21554934 Epas1 Mouse ochratoxin A decreases expression ISO EPAS1 (Homo sapiens) 6480464 ochratoxin A results in decreased expression of EPAS1 protein CTD PMID:21554934 Epas1 Mouse okadaic acid increases expression ISO EPAS1 (Homo sapiens) 6480464 Okadaic Acid results in increased expression of EPAS1 mRNA CTD PMID:28939011 Epas1 Mouse ozone decreases expression ISO Epas1 (Rattus norvegicus) 6480464 Ozone results in decreased expression of EPAS1 mRNA CTD PMID:28549673 Epas1 Mouse ozone multiple interactions EXP 6480464 [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in decreased expression of EPAS1 mRNA CTD PMID:34911549 Epas1 Mouse panobinostat increases expression ISO EPAS1 (Homo sapiens) 6480464 panobinostat results in increased expression of EPAS1 mRNA CTD PMID:26272509 Epas1 Mouse panobinostat multiple interactions ISO EPAS1 (Homo sapiens) 6480464 [NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of EPAS1 mRNA CTD PMID:27188386 Epas1 Mouse paracetamol increases expression ISO Epas1 (Rattus norvegicus) 6480464 Acetaminophen results in increased expression of EPAS1 mRNA CTD PMID:33387578 Epas1 Mouse perfluorooctane-1-sulfonic acid multiple interactions EXP 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of EPAS1 mRNA CTD PMID:36331819 Epas1 Mouse perfluorooctanoic acid multiple interactions ISO Epas1 (Rattus norvegicus) 6480464 [Zeranol co-treated with perfluorooctanoic acid] results in increased expression of EPAS1 mRNA CTD PMID:35163327 Epas1 Mouse pevonedistat multiple interactions ISO EPAS1 (Homo sapiens) 6480464 [Formaldehyde co-treated with pevonedistat co-treated with benzyloxycarbonylleucyl-leucyl-leucine aldehyde] affects the folding of EPAS1 protein CTD PMID:35504338 Epas1 Mouse phenylephrine decreases expression ISO Epas1 (Rattus norvegicus) 6480464 Phenylephrine results in decreased expression of EPAS1 mRNA CTD PMID:18158353 Epas1 Mouse phenylmercury acetate increases expression ISO EPAS1 (Homo sapiens) 6480464 Phenylmercuric Acetate results in increased expression of EPAS1 mRNA CTD PMID:26272509 Epas1 Mouse phenylmercury acetate multiple interactions ISO EPAS1 (Homo sapiens) 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of EPAS1 mRNA CTD PMID:27188386 Epas1 Mouse phorbol 13-acetate 12-myristate multiple interactions EXP 6480464 [Methylcholanthrene co-treated with Tetradecanoylphorbol Acetate] results in decreased expression of EPAS1 mRNA CTD PMID:23519560 Epas1 Mouse phosphane increases expression ISO Epas1 (Rattus norvegicus) 6480464 phosphine results in increased expression of EPAS1 mRNA CTD PMID:34427094 Epas1 Mouse pirinixic acid increases expression EXP 6480464 pirinixic acid results in increased expression of EPAS1 mRNA CTD PMID:17426115 and PMID:18301758 Epas1 Mouse piroxicam decreases expression ISO EPAS1 (Homo sapiens) 6480464 Piroxicam results in decreased expression of EPAS1 mRNA CTD PMID:21858171 Epas1 Mouse pregnenolone 16alpha-carbonitrile increases expression EXP 6480464 Pregnenolone Carbonitrile results in increased expression of EPAS1 mRNA CTD PMID:28903501 Epas1 Mouse protoporphyrin affects localization ISO EPAS1 (Homo sapiens) 6480464 protoporphyrin IX affects the localization of EPAS1 protein CTD PMID:23624237 Epas1 Mouse quercetin multiple interactions ISO EPAS1 (Homo sapiens) 6480464 ferrous sulfate inhibits the reaction [Quercetin results in increased expression of EPAS1 protein] and Iron inhibits the reaction [Quercetin results in increased expression of EPAS1 protein] CTD PMID:17973296 Epas1 Mouse quercetin increases expression ISO EPAS1 (Homo sapiens) 6480464 Quercetin results in increased expression of EPAS1 protein CTD PMID:17973296 Epas1 Mouse quercitrin increases expression ISO EPAS1 (Homo sapiens) 6480464 quercitrin results in increased expression of EPAS1 mRNA CTD PMID:25193878 Epas1 Mouse rifampicin multiple interactions ISO EPAS1 (Homo sapiens) 6480464 [Rifampin co-treated with NR1I2 protein] results in increased expression of EPAS1 mRNA CTD PMID:21127053 Epas1 Mouse rotenone multiple interactions ISO Epas1 (Rattus norvegicus) 6480464 Rotenone inhibits the reaction [Oxygen deficiency results in increased expression of EPAS1 protein] CTD PMID:18353899 Epas1 Mouse rotenone decreases expression ISO EPAS1 (Homo sapiens) 6480464 Rotenone results in decreased expression of EPAS1 mRNA CTD PMID:29955902 Epas1 Mouse SB 431542 multiple interactions ISO EPAS1 (Homo sapiens) 6480464 [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 Epas1 Mouse silicon dioxide increases expression ISO EPAS1 (Homo sapiens) 6480464 Silicon Dioxide analog results in increased expression of EPAS1 mRNA CTD PMID:25895662 Epas1 Mouse silver atom decreases expression EXP 6480464 Silver results in decreased expression of EPAS1 mRNA CTD PMID:27131904 Epas1 Mouse silver(0) decreases expression EXP 6480464 Silver results in decreased expression of EPAS1 mRNA CTD PMID:27131904 Epas1 Mouse sodium arsenite multiple interactions ISO EPAS1 (Homo sapiens) 6480464 [MALAT1 mRNA affects the susceptibility to sodium arsenite] which results in decreased hydroxylation of EPAS1 protein more ... CTD PMID:22662215 more ... Epas1 Mouse sodium arsenite increases expression EXP 6480464 sodium arsenite results in increased expression of EPAS1 protein CTD PMID:26735578 Epas1 Mouse sodium arsenite increases expression ISO EPAS1 (Homo sapiens) 6480464 sodium arsenite results in increased expression of EPAS1 mRNA and sodium arsenite results in increased expression of EPAS1 protein CTD PMID:22662215 more ... Epas1 Mouse sodium arsenite affects response to substance ISO EPAS1 (Homo sapiens) 6480464 EPAS1 protein affects the susceptibility to sodium arsenite CTD PMID:23333640 Epas1 Mouse sodium cyanide multiple interactions ISO Epas1 (Rattus norvegicus) 6480464 Sodium Cyanide inhibits the reaction [Oxygen deficiency results in increased expression of EPAS1 protein] CTD PMID:18353899 Epas1 Mouse sotorasib multiple interactions ISO EPAS1 (Homo sapiens) 6480464 [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of EPAS1 mRNA CTD PMID:36139627 Epas1 Mouse squalene decreases expression ISO EPAS1 (Homo sapiens) 6480464 Squalene results in decreased expression of EPAS1 mRNA and Squalene results in decreased expression of EPAS1 protein CTD PMID:33219891 Epas1 Mouse sunitinib decreases expression ISO EPAS1 (Homo sapiens) 6480464 Sunitinib results in decreased expression of EPAS1 mRNA CTD PMID:31533062 Epas1 Mouse T-2 toxin multiple interactions EXP 6480464 BAY 11-7085 inhibits the reaction [T-2 Toxin results in increased expression of EPAS1 mRNA] and BAY 11-7085 inhibits the reaction [T-2 Toxin results in increased expression of EPAS1 protein] CTD PMID:22800716 Epas1 Mouse T-2 toxin increases expression ISO EPAS1 (Homo sapiens) 6480464 T-2 Toxin results in increased expression of EPAS1 mRNA CTD PMID:34581912 Epas1 Mouse T-2 toxin increases expression EXP 6480464 T-2 Toxin results in increased expression of EPAS1 mRNA and T-2 Toxin results in increased expression of EPAS1 protein CTD PMID:22800716 Epas1 Mouse temozolomide decreases expression ISO EPAS1 (Homo sapiens) 6480464 Temozolomide results in decreased expression of EPAS1 mRNA CTD PMID:31758290 Epas1 Mouse thapsigargin decreases expression ISO EPAS1 (Homo sapiens) 6480464 Thapsigargin results in decreased expression of EPAS1 mRNA CTD PMID:22378314 Epas1 Mouse titanium dioxide decreases methylation EXP 6480464 titanium dioxide results in decreased methylation of EPAS1 gene CTD PMID:35295148 Epas1 Mouse titanium dioxide increases methylation EXP 6480464 titanium dioxide results in increased methylation of EPAS1 promoter CTD PMID:35295148 Epas1 Mouse topotecan multiple interactions ISO EPAS1 (Homo sapiens) 6480464 Topotecan inhibits the reaction [sodium arsenite results in increased expression of EPAS1 protein] CTD PMID:30090327 Epas1 Mouse trametinib multiple interactions ISO EPAS1 (Homo sapiens) 6480464 [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of EPAS1 mRNA CTD PMID:36139627 Epas1 Mouse trichloroethene decreases expression EXP 6480464 Trichloroethylene results in decreased expression of EPAS1 mRNA CTD PMID:19448997 Epas1 Mouse trichloroethene increases expression ISO Epas1 (Rattus norvegicus) 6480464 Trichloroethylene results in increased expression of EPAS1 mRNA CTD PMID:33387578 Epas1 Mouse trichloroethene increases expression EXP 6480464 Trichloroethylene results in increased expression of EPAS1 mRNA CTD PMID:15363585 Epas1 Mouse trichostatin A increases expression ISO EPAS1 (Homo sapiens) 6480464 trichostatin A results in increased expression of EPAS1 mRNA CTD PMID:24935251 more ... Epas1 Mouse trichostatin A multiple interactions ISO EPAS1 (Homo sapiens) 6480464 [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of EPAS1 mRNA CTD PMID:27188386 Epas1 Mouse triphenyl phosphate affects expression ISO EPAS1 (Homo sapiens) 6480464 triphenyl phosphate affects the expression of EPAS1 mRNA CTD PMID:37042841 Epas1 Mouse triptonide increases expression EXP 6480464 triptonide results in increased expression of EPAS1 mRNA CTD PMID:33045310 Epas1 Mouse troglitazone decreases expression EXP 6480464 troglitazone results in decreased expression of EPAS1 mRNA CTD PMID:28973697 Epas1 Mouse tunicamycin decreases expression ISO EPAS1 (Homo sapiens) 6480464 Tunicamycin results in decreased expression of EPAS1 mRNA CTD PMID:22378314 Epas1 Mouse valproic acid multiple interactions ISO EPAS1 (Homo sapiens) 6480464 [Hydralazine co-treated with Valproic Acid] results in increased expression of EPAS1 mRNA more ... CTD PMID:17183730 and PMID:27188386 Epas1 Mouse valproic acid affects splicing ISO Epas1 (Rattus norvegicus) 6480464 Valproic Acid affects the splicing of EPAS1 mRNA CTD PMID:29427782 Epas1 Mouse valproic acid increases expression ISO EPAS1 (Homo sapiens) 6480464 Valproic Acid results in increased expression of EPAS1 mRNA CTD PMID:23179753 more ... Epas1 Mouse valproic acid affects expression EXP 6480464 Valproic Acid affects the expression of EPAS1 mRNA CTD PMID:17292431 Epas1 Mouse vinclozolin affects expression ISO Epas1 (Rattus norvegicus) 6480464 vinclozolin affects the expression of EPAS1 mRNA CTD PMID:19015723 Epas1 Mouse vinclozolin increases methylation ISO Epas1 (Rattus norvegicus) 6480464 vinclozolin results in increased methylation of EPAS1 gene CTD PMID:31079544 Epas1 Mouse vinclozolin decreases expression ISO Epas1 (Rattus norvegicus) 6480464 vinclozolin results in decreased expression of EPAS1 mRNA CTD PMID:30207508 Epas1 Mouse vorinostat decreases expression ISO EPAS1 (Homo sapiens) 6480464 vorinostat results in decreased expression of EPAS1 mRNA CTD PMID:18769122 Epas1 Mouse zearalenone increases expression EXP 6480464 Zearalenone results in increased expression of EPAS1 mRNA CTD PMID:30138655