Grid2 (glutamate receptor, ionotropic, delta 2) - Rat Genome Database

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Gene: Grid2 (glutamate receptor, ionotropic, delta 2) Mus musculus
Analyze
Symbol: Grid2
Name: glutamate receptor, ionotropic, delta 2
RGD ID: 68528
MGI Page MGI
Description: Enables PDZ domain binding activity and scaffold protein binding activity. Involved in several processes, including cerebellar granule cell differentiation; heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules; and regulation of postsynaptic density assembly. Acts upstream of or within several processes, including chemical synaptic transmission; prepulse inhibition; and regulation of neuron apoptotic process. Located in dendritic spine and postsynaptic membrane. Part of ionotropic glutamate receptor complex. Is active in glutamatergic synapse; parallel fiber to Purkinje cell synapse; and postsynaptic density membrane. Is expressed in several structures, including brain; eye; genitourinary system; intestine; and spinal cord. Used to study autosomal recessive spinocerebellar ataxia 18. Human ortholog(s) of this gene implicated in autosomal recessive spinocerebellar ataxia 18. Orthologous to human GRID2 (glutamate ionotropic receptor delta type subunit 2).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: B230104L07Rik; cpr; creeper; GluD2; gluR delta-2 subunit; GluRde; GluRdelta2; glutamate receptor delta-2 subunit; glutamate receptor ionotropic, delta-2; ho; hotfoot; Lc; Lc; lurcher; minisatellite 10ac detected by probe MMS10; MMS10-AC; Ms10ac; nmf408; t; tpr
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39663,230,118 - 64,681,305 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl663,232,860 - 64,681,307 (+)EnsemblGRCm39 Ensembl
GRCm38663,256,006 - 64,704,321 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl663,255,876 - 64,704,323 (+)EnsemblGRCm38mm10GRCm38
MGSCv37663,206,851 - 64,616,273 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36663,186,435 - 64,595,857 (+)NCBIMGSCv36mm8
Celera665,396,130 - 66,793,674 (+)NCBICelera
Cytogenetic Map6C1NCBI
cM Map629.77NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal action potential  (IAGP)
abnormal autophagy  (IAGP)
abnormal cerebellar cortex morphology  (IAGP)
abnormal cerebellar foliation  (IAGP)
abnormal cerebellar granule layer morphology  (IAGP)
abnormal cerebellar molecular layer  (IAGP)
abnormal cerebellar Purkinje cell layer  (IAGP)
abnormal cerebellum development  (IAGP)
abnormal cerebellum lobule morphology  (IAGP)
abnormal cerebellum morphology  (IAGP)
abnormal CNS synapse formation  (IAGP)
abnormal CNS synaptic transmission  (IAGP)
abnormal cochlear VIII nucleus morphology  (IAGP)
abnormal discrimination learning  (IAGP)
abnormal excitatory postsynaptic current amplitude  (IAGP)
abnormal excitatory postsynaptic currents  (IAGP)
abnormal eye blink conditioning behavior  (IAGP)
abnormal eye movement  (IAGP)
abnormal fertility/fecundity  (IAGP)
abnormal GABA-mediated receptor currents  (IAGP)
abnormal gait  (IAGP)
abnormal grooming behavior  (IAGP)
abnormal head movements  (IEA)
abnormal hindbrain morphology  (IAGP)
abnormal locomotor activation  (IAGP)
abnormal locomotor coordination  (IAGP)
abnormal midbrain morphology  (IAGP)
abnormal motor capabilities/coordination/movement  (IEA)
abnormal motor coordination/balance  (IAGP)
abnormal motor learning  (IAGP)
abnormal myelination  (IEA)
abnormal neuron morphology  (IAGP)
abnormal optokinetic reflex  (IAGP)
abnormal posture  (IAGP)
abnormal Purkinje cell dendrite morphology  (IAGP)
abnormal Purkinje cell innervation  (IAGP)
abnormal Purkinje cell mitochondrial morphology  (IAGP)
abnormal Purkinje cell morphology  (IAGP)
abnormal reflex  (IAGP)
abnormal response to injury  (IAGP)
abnormal resting posture  (IEA)
abnormal sensory capabilities/reflexes/nociception  (IAGP)
abnormal sexual interaction  (IEA)
abnormal spatial learning  (IAGP)
abnormal sperm flagellum morphology  (IAGP)
abnormal sperm motility  (IAGP)
abnormal suckling behavior  (IAGP)
abnormal synapse morphology  (IAGP)
abnormal synaptic neurotransmitter level  (IAGP)
abnormal trigeminal motor nucleus morphology  (IAGP)
abnormal vestibuloocular reflex  (IAGP)
absent gastric milk in neonates  (IAGP)
absent long-term depression  (IAGP)
ataxia  (IAGP)
athetotic walking movements  (IEA)
bradykinesia  (IAGP)
cerebellum atrophy  (IAGP)
decreased birth weight  (IAGP)
decreased body size  (IAGP)
decreased body weight  (IAGP)
decreased cerebellar granule cell number  (IAGP)
decreased CNS synapse formation  (IAGP)
decreased exploration in new environment  (IAGP)
decreased locomotor activity  (IAGP)
decreased Purkinje cell number  (IAGP)
decreased survivor rate  (IEA)
decreased vertical activity  (IAGP)
head tilt  (IAGP)
hindlimb paralysis  (IAGP)
hyperactivity  (IAGP)
hypoxia  (IAGP)
impaired balance  (IAGP)
impaired coordination  (IAGP)
impaired fertilization  (IAGP)
impaired limb coordination  (IAGP)
impaired righting response  (IAGP)
impaired sperm penetration of zona pellucida  (IAGP)
increased circulating adrenocorticotropin level  (IAGP)
increased circulating corticosterone level  (IAGP)
increased miniature inhibitory postsynaptic current amplitude  (IAGP)
increased neurotransmitter release  (IAGP)
increased or absent threshold for auditory brainstem response  (IEA)
increased prepulse inhibition  (IAGP)
jerky movement  (IAGP)
lethality at weaning, complete penetrance  (IAGP)
lethargy  (IEA)
limb grasping  (IAGP)
male infertility  (IEA)
muscle spasm  (IEA)
neonatal lethality, complete penetrance  (IAGP)
neonatal lethality, incomplete penetrance  (IAGP)
postnatal lethality  (IEA)
prolonged excitatory postsynaptic current decay time  (IAGP)
prolonged excitatory postsynaptic current rise time  (IAGP)
Purkinje cell degeneration  (IAGP)
reduced cerebellar foliation  (IAGP)
reduced female fertility  (IAGP)
reduced linear vestibular evoked potential  (IAGP)
reduced long-term depression  (IAGP)
reduced male fertility  (IAGP)
retropulsion  (IAGP)
short stride length  (IAGP)
small cerebellum  (IAGP)
stereotypic behavior  (IEA)
thin cerebellar molecular layer  (IAGP)
thin external granule cell layer  (IAGP)
titubation  (IAGP)
tremors  (IEA)
weaving  (IAGP)
References

References - curated
# Reference Title Reference Citation
1. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
2. MGDs mouse GO annotations MGD data from the GO Consortium
3. MGD IEA MGD IEA
4. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
5. Mouse MP Annotation Import Pipeline RGD automated import pipeline
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:41272   PMID:845284   PMID:1358814   PMID:1372540   PMID:1430312   PMID:1464763   PMID:1500948   PMID:1506853   PMID:1523229   PMID:1541724   PMID:1565842   PMID:1672287  
PMID:1689261   PMID:1786651   PMID:1804324   PMID:2077109   PMID:2230805   PMID:2355223   PMID:2400906   PMID:3443296   PMID:4015615   PMID:4092923   PMID:4595403   PMID:6184821  
PMID:6652508   PMID:7108427   PMID:7119869   PMID:7171994   PMID:7478307   PMID:7506541   PMID:7517964   PMID:7656422   PMID:7666163   PMID:7673465   PMID:7673468   PMID:7736576  
PMID:7743930   PMID:7766857   PMID:7792064   PMID:7872930   PMID:7886086   PMID:7891151   PMID:7914819   PMID:7931420   PMID:8027434   PMID:8027435   PMID:8081710   PMID:8205489  
PMID:8230318   PMID:8242378   PMID:8327607   PMID:8339786   PMID:8350981   PMID:8395631   PMID:8402174   PMID:8509510   PMID:8513552   PMID:8568721   PMID:8614556   PMID:8680799  
PMID:8738121   PMID:8742448   PMID:8750197   PMID:8833100   PMID:8846072   PMID:8848495   PMID:8851932   PMID:8910533   PMID:8973844   PMID:9027408   PMID:9037414   PMID:9065501  
PMID:9174242   PMID:9175096   PMID:9252230   PMID:9253602   PMID:9253946   PMID:9271665   PMID:9285588   PMID:9305822   PMID:9383282   PMID:9387853   PMID:9391016   PMID:9412510  
PMID:9460703   PMID:9465309   PMID:9514513   PMID:9570718   PMID:9578449   PMID:9628817   PMID:9661982   PMID:9698188   PMID:9733904   PMID:9754955   PMID:9758150   PMID:9767169  
PMID:9803023   PMID:9804384   PMID:9813051   PMID:9813341   PMID:9831049   PMID:9926858   PMID:10212305   PMID:10230710   PMID:10349636   PMID:10371649   PMID:10583470   PMID:10648704  
PMID:10748123   PMID:10756063   PMID:10775492   PMID:10804210   PMID:10884318   PMID:10952061   PMID:11042159   PMID:11076861   PMID:11144029   PMID:11210178   PMID:11217851   PMID:11226698  
PMID:11243853   PMID:11279275   PMID:11285022   PMID:11434974   PMID:11488959   PMID:11489994   PMID:11545532   PMID:11672610   PMID:11722613   PMID:11739579   PMID:11826110   PMID:11934869  
PMID:11984816   PMID:12351723   PMID:12355415   PMID:12372286   PMID:12405964   PMID:12408845   PMID:12466851   PMID:12477932   PMID:12513910   PMID:12514196   PMID:12573530   PMID:12628171  
PMID:12725908   PMID:12752376   PMID:12805289   PMID:12833050   PMID:12862360   PMID:14605869   PMID:14635229   PMID:14637233   PMID:15014119   PMID:15019569   PMID:15033168   PMID:15033280  
PMID:15078542   PMID:15140011   PMID:15163686   PMID:15207857   PMID:15531086   PMID:15574740   PMID:15579147   PMID:15592450   PMID:15674731   PMID:15728855   PMID:15787704   PMID:15813941  
PMID:16141072   PMID:16141073   PMID:16165299   PMID:16168524   PMID:16234806   PMID:16235133   PMID:16271355   PMID:16412991   PMID:16499884   PMID:16597715   PMID:16636065   PMID:16647695  
PMID:16723418   PMID:16739195   PMID:16860885   PMID:16885219   PMID:16919269   PMID:17255161   PMID:17298852   PMID:17425562   PMID:17425572   PMID:17604104   PMID:17663432   PMID:17702810  
PMID:17715062   PMID:17978051   PMID:18243354   PMID:18249497   PMID:18256267   PMID:18279360   PMID:18287559   PMID:18341993   PMID:18418877   PMID:18498740   PMID:18509461   PMID:18551174  
PMID:18583162   PMID:18677091   PMID:19000899   PMID:19142228   PMID:19250438   PMID:19258455   PMID:19294643   PMID:19370152   PMID:19402746   PMID:19420242   PMID:19614753   PMID:20105240  
PMID:20130198   PMID:20231872   PMID:20387025   PMID:20395510   PMID:20417257   PMID:20472884   PMID:20535596   PMID:20537373   PMID:20566377   PMID:20599760   PMID:21068325   PMID:21089334  
PMID:21267068   PMID:21368048   PMID:21460832   PMID:21551723   PMID:21628556   PMID:21873635   PMID:22279216   PMID:22457515   PMID:22542190   PMID:22794259   PMID:22915109   PMID:23077633  
PMID:23115168   PMID:23136008   PMID:23431139   PMID:23436049   PMID:23564161   PMID:23570728   PMID:23672668   PMID:23970854   PMID:24078737   PMID:24109434   PMID:24357660   PMID:24467251  
PMID:24811382   PMID:24872547   PMID:24937052   PMID:24952961   PMID:25001082   PMID:25127140   PMID:25155577   PMID:25250835   PMID:25513882   PMID:25907855   PMID:25917818   PMID:26029065  
PMID:26607150   PMID:27118840   PMID:27122040   PMID:27242661   PMID:27820843   PMID:28007900   PMID:28502476   PMID:28696429   PMID:29166599   PMID:29777493   PMID:29782851   PMID:29972794  
PMID:30013234   PMID:30979012   PMID:31118204   PMID:31625608   PMID:31941824   PMID:32088197   PMID:32109557   PMID:32325033   PMID:32855309   PMID:33091448   PMID:33305180   PMID:33352118  
PMID:34135511   PMID:34815492   PMID:36162328   PMID:36395107   PMID:36447271   PMID:38310234   PMID:38333701  


Genomics

Comparative Map Data
Grid2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39663,230,118 - 64,681,305 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl663,232,860 - 64,681,307 (+)EnsemblGRCm39 Ensembl
GRCm38663,256,006 - 64,704,321 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl663,255,876 - 64,704,323 (+)EnsemblGRCm38mm10GRCm38
MGSCv37663,206,851 - 64,616,273 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36663,186,435 - 64,595,857 (+)NCBIMGSCv36mm8
Celera665,396,130 - 66,793,674 (+)NCBICelera
Cytogenetic Map6C1NCBI
cM Map629.77NCBI
GRID2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38492,303,966 - 93,810,456 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl492,303,966 - 93,810,157 (+)EnsemblGRCh38hg38GRCh38
GRCh37493,225,117 - 94,695,717 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36493,444,573 - 94,912,672 (+)NCBINCBI36Build 36hg18NCBI36
Build 34493,582,985 - 95,050,827NCBI
Celera490,516,237 - 91,989,747 (+)NCBICelera
Cytogenetic Map4q22.1-q22.2NCBI
HuRef488,967,871 - 90,430,993 (+)NCBIHuRef
CHM1_1493,202,022 - 94,670,166 (+)NCBICHM1_1
T2T-CHM13v2.0495,630,513 - 97,125,831 (+)NCBIT2T-CHM13v2.0
Grid2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8493,745,165 - 95,222,354 (+)NCBIGRCr8
mRatBN7.2492,415,019 - 93,892,472 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl492,415,230 - 93,889,355 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx497,627,719 - 99,083,931 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0493,402,958 - 94,858,882 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0491,821,373 - 93,281,846 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0494,068,112 - 95,476,864 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl494,696,965 - 95,442,778 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04158,857,267 - 160,262,923 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4492,642,427 - 94,054,757 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1492,886,907 - 94,299,238 (+)NCBI
Celera487,164,582 - 88,604,118 (+)NCBICelera
Cytogenetic Map4q31NCBI
Grid2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554053,344,763 - 4,443,836 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554053,291,793 - 4,411,249 (+)NCBIChiLan1.0ChiLan1.0
GRID2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2390,328,906 - 91,836,156 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1490,606,840 - 92,114,771 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0484,663,030 - 86,170,778 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1495,339,204 - 96,809,804 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl495,339,460 - 96,807,748 (+)Ensemblpanpan1.1panPan2
GRID2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13215,322,256 - 16,787,966 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3215,322,738 - 16,753,656 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3225,156,550 - 26,624,358 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03215,494,314 - 16,970,466 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3215,494,520 - 16,934,050 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13215,474,650 - 16,942,531 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03215,290,434 - 16,758,200 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03223,136,174 - 24,607,929 (-)NCBIUU_Cfam_GSD_1.0
Grid2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530124,925,851 - 26,327,389 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936687549,947 - 1,421,133 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493668720,126 - 1,421,075 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GRID2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl8125,819,951 - 127,129,763 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.18125,821,195 - 127,130,617 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.28135,414,934 - 135,568,963 (-)NCBISscrofa10.2Sscrofa10.2susScr3
GRID2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1740,585,532 - 42,079,977 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366603718,927,676 - 20,401,397 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Grid2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475719,967,840 - 21,498,318 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475719,967,428 - 21,497,009 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1567
Count of miRNA genes:727
Interacting mature miRNAs:955
Transcripts:ENSMUST00000095852, ENSMUST00000159319, ENSMUST00000159561, ENSMUST00000160408, ENSMUST00000161105, ENSMUST00000162968
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4142271Egq8_mearly growth QTL 8 (mouse)Not determined450382396633110Mouse
1301266Lmr4_mleishmaniasis resistance 4 (mouse)Not determined64209335876093500Mouse
12910785Pwgrq16_mpost-weaning growth rate QTL 16 (mouse)64380374777788506Mouse
11252142Mom12_mModifier of Min 12 (mouse)63387226167872400Mouse
4140983Srilp_msleep response to influenza, light phase (mouse)Not determined4870349075424693Mouse
12910798Pwgrq5_mpre-weaning growth rate QTL 5 (mouse)64380374777788506Mouse
1300767Aliq4_macute lung injury QTL 4 (mouse)Not determined63627333270273435Mouse
4142259Tabw2_mtally ho associated body weight 2 (mouse)Not determined46912919136400690Mouse
25314319Histh6_mhistamine hypersensitivity 6 (mouse)648696934125336963Mouse
4142126W3q3_mweight 3 weeks QTL 3 (mouse)Not determined450382396633110Mouse
25314320Histh5_mhistamine hypersensitivity 5 (mouse)648696934148351498Mouse
12910807Pwbwq11_mpost-weaning body weight QTL 11 (mouse)64380374777788506Mouse
14746995Manh60_mmandible shape 60 (mouse)63720266271202662Mouse
1301254Skts11_mskin tumor susceptibility 11 (mouse)Not determined65115613485156284Mouse
1357442Dbts1_mdiabetes 1 (mouse)Not determined61823414773364675Mouse
12910802Pwbwq12_mpost-weaning body weight QTL 12 (mouse)64380374777788506Mouse
14700792Mencq5_mmeniscus calcification QTL 5 (mouse)65959198563331984Mouse
4141094Hrtr1_mheart rate 1 (mouse)Not determined3674146370741463Mouse
1300618Pgia19_mproteoglycan induced arthritis 19 (mouse)Not determined64529099387403016Mouse
12910809Pwbwq10_mpost-weaning body weight QTL 10 (mouse)64380374777788506Mouse
12910820Ogrq3_moverall growth rate QTL 3 (mouse)64380374777788506Mouse
26884414Bzwq12_mbi-zygomatic width QTL 12, 16 week (mouse)63400000139076998Mouse
4142361W10q11_mweight 10 weeks QTL 11 (mouse)Not determined450382396633110Mouse
4142232W6q4_mweight 6 weeks QTL 4 (mouse)Not determined450382396633110Mouse
10412213Sxbq2_mSGC/Knj cross B6 QTL 2 (mouse)Not determined61991268571299759Mouse
4141454Obrq4_mobesity resistance QTL 4 (mouse)Not determined3170349965703611Mouse
13208564Bmiq7_mbody mass index QTL 7 (mouse)62499999979976983Mouse
26884441Sklq3_mskull length QTL 3, 5 week (mouse)6760000080576983Mouse
10412119Stv_mstriatal volumne (mouse)Not determined660026991100026967Mouse
1300959Lxw2_mlupus BXSB x NZW 2 (mouse)Not determined63387226167872400Mouse
1558977Skmw10_mskeletal muscle weight 10 (mouse)Not determined65842456692424693Mouse
1301962Eila2_methanol induced locomotor activity 2 (mouse)Not determined648703490125333748Mouse
4141028Mclr_mmethylcholanthrene lymphoma resistance (mouse)Not determined5435041188356155Mouse
1301326Trbv4c2_mT cell receptor beta variable 4 (mouse)Not determined64086823071356155Mouse
10043972Obq28_mobesity QTL 28 (mouse)Not determined65851741692517416Mouse
1558984Cplaq9_mcircadian period of locomotor activity 9 (mouse)Not determined63864656092584431Mouse
1300556Cia6_mcollagen induced arthritis QTL 6 (mouse)Not determined6446488487403016Mouse
10412157Fl1n_mfatty liver 1 in NSY (mouse)Not determined645290993128811995Mouse
25440480Moaq2_mmodifier of alien QTL 2 (mouse)63050001117476961Mouse
1357683Igf1sl1_mIGF-1 serum levels 1 (mouse)Not determined652138693116132228Mouse
15039373Adip28_madiposity 28 (mouse)65628519490285194Mouse
4141782Mrdq5_mmodifier of retinal degeneration QTL 5 (mouse)Not determined3282758578215957Mouse
1301369Im4_mimmunoregulatory 4 (mouse)Not determined66346172197461888Mouse
15039375Bw41_mbody weight QTL 41 (mouse)65628519490285194Mouse
12880424V25Dq4_mvitamin D inactive form serum level QTL 4 (mouse)64157698575576985Mouse
12880425V25Dq5_mvitamin D inactive form serum level QTL 5 (mouse)63267698066676980Mouse
11040600Lmr4c_mleishmaniasis resistance 4c (mouse)64209335876093500Mouse
11040601Lmr4a_mleishmaniasis resistance 4a (mouse)64209335876093500Mouse
10043885Cia6c_mcollagen induced arthritis QTL 6c (mouse)Not determined64444280571096451Mouse
11533915Mts4_mmammary tumor susceptibility 4 (mouse)64209335876093500Mouse
1357539Bsbob3_mBSB obesity 3 (mouse)Not determined63644845670448576Mouse
1301740Bwq2_mbody weight QTL 2 (mouse)Not determined66003466394034782Mouse

Markers in Region
AI450142  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38664,668,084 - 64,668,219UniSTSGRCm38
MGSCv37664,618,078 - 64,618,213UniSTSGRCm37
Celera666,795,479 - 66,795,614UniSTS
Cytogenetic Map6C1UniSTS
cM Map629.65UniSTS
Whitehead/MRC_RH6656.56UniSTS
RH118302  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38664,239,591 - 64,239,772UniSTSGRCm38
MGSCv37664,189,585 - 64,189,766UniSTSGRCm37
Celera666,374,074 - 66,374,255UniSTS
Cytogenetic Map6C1UniSTS
cM Map629.65UniSTS
Whitehead/MRC_RH6658.33UniSTS
Whitehead_YAC6 UniSTS
24.MMHAP88FLH3.seq  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38663,620,692 - 63,620,874UniSTSGRCm38
MGSCv37663,570,686 - 63,570,868UniSTSGRCm37
Celera665,758,154 - 65,758,336UniSTS
Cytogenetic Map6C1UniSTS
cM Map629.65UniSTS
Whitehead_YAC6 UniSTS
29.MHAa92c5.seq  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38664,026,935 - 64,027,106UniSTSGRCm38
MGSCv37663,976,929 - 63,977,100UniSTSGRCm37
Celera666,167,337 - 66,167,508UniSTS
Cytogenetic Map6C1UniSTS
cM Map629.65UniSTS
Whitehead_YAC6 UniSTS
32.MMHAP88FLC5.seq  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38664,129,471 - 64,129,642UniSTSGRCm38
MGSCv37664,079,465 - 64,079,636UniSTSGRCm37
Celera666,269,755 - 66,269,926UniSTS
Cytogenetic Map6C1UniSTS
cM Map629.65UniSTS
Whitehead_YAC6 UniSTS
40.MMHAP64FRF10.seq  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38663,773,612 - 63,773,779UniSTSGRCm38
MGSCv37663,723,606 - 63,723,773UniSTSGRCm37
Celera665,913,078 - 65,913,245UniSTS
Cytogenetic Map6C1UniSTS
cM Map629.65UniSTS
Whitehead_YAC6 UniSTS
D6Mit121  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38663,430,907 - 63,431,001UniSTSGRCm38
MGSCv37663,380,901 - 63,380,995UniSTSGRCm37
Celera665,568,660 - 65,568,754UniSTS
Cytogenetic Map6C1UniSTS
cM Map629.42UniSTS
Whitehead Genetic617.5UniSTS
Whitehead/MRC_RH6639.62UniSTS
BF390815  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38664,548,726 - 64,548,855UniSTSGRCm38
MGSCv37664,498,720 - 64,498,849UniSTSGRCm37
Celera666,683,421 - 66,683,550UniSTS
Cytogenetic Map6C1UniSTS
cM Map629.65UniSTS
D6Rck314  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38663,734,784 - 63,735,034UniSTSGRCm38
MGSCv37663,684,778 - 63,685,028UniSTSGRCm37
Celera665,873,656 - 65,873,906UniSTS
Cytogenetic Map6C1UniSTS
cM Map629.46UniSTS
D6Rck301  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38663,360,427 - 63,360,673UniSTSGRCm38
MGSCv37663,310,421 - 63,310,667UniSTSGRCm37
Celera665,498,190 - 65,498,436UniSTS
Cytogenetic Map6C1UniSTS
cM Map629.38UniSTS
D6Rck317  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38663,856,011 - 63,856,294UniSTSGRCm38
MGSCv37663,806,005 - 63,806,288UniSTSGRCm37
Celera665,995,865 - 65,996,148UniSTS
Cytogenetic Map6C1UniSTS
cM Map629.55UniSTS
D6Rck324  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38664,002,408 - 64,002,716UniSTSGRCm38
MGSCv37663,952,402 - 63,952,710UniSTSGRCm37
Celera666,142,746 - 66,143,054UniSTS
Cytogenetic Map6C1UniSTS
cM Map629.57UniSTS
D6Rck325  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38663,946,662 - 63,946,912UniSTSGRCm38
MGSCv37663,896,656 - 63,896,906UniSTSGRCm37
Celera666,087,032 - 66,087,282UniSTS
Cytogenetic Map6C1UniSTS
cM Map629.59UniSTS
D6Rck344  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38664,079,597 - 64,079,884UniSTSGRCm38
MGSCv37664,029,591 - 64,029,878UniSTSGRCm37
Celera666,219,903 - 66,220,190UniSTS
Cytogenetic Map6C1UniSTS
cM Map629.61UniSTS
D6Rck345  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38664,154,051 - 64,154,350UniSTSGRCm38
MGSCv37664,104,045 - 64,104,344UniSTSGRCm37
Celera666,294,335 - 66,294,634UniSTS
Cytogenetic Map6C1UniSTS
cM Map629.62UniSTS
D6Rck346  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38664,169,062 - 64,169,408UniSTSGRCm38
MGSCv37664,119,056 - 64,119,402UniSTSGRCm37
Celera666,303,123 - 66,303,469UniSTS
Cytogenetic Map6C1UniSTS
cM Map6 UniSTS
D6Rck347  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38664,218,647 - 64,218,866UniSTSGRCm38
MGSCv37664,168,641 - 64,168,860UniSTSGRCm37
Celera666,353,130 - 66,353,349UniSTS
Cytogenetic Map6C1UniSTS
cM Map6 UniSTS
D6Rck354  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38664,395,641 - 64,395,970UniSTSGRCm38
MGSCv37664,345,635 - 64,345,964UniSTSGRCm37
Celera666,530,462 - 66,530,791UniSTS
Cytogenetic Map6C1UniSTS
cM Map6 UniSTS
D6Rck357  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38664,444,989 - 64,445,252UniSTSGRCm38
MGSCv37664,394,983 - 64,395,246UniSTSGRCm37
Celera666,579,627 - 66,579,890UniSTS
Cytogenetic Map6C1UniSTS
cM Map629.66UniSTS
D6Rck358  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38664,447,738 - 64,448,093UniSTSGRCm38
MGSCv37664,397,732 - 64,398,087UniSTSGRCm37
Celera666,582,377 - 66,582,732UniSTS
Cytogenetic Map6C1UniSTS
cM Map6 UniSTS
D6Rck359  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38664,447,814 - 64,448,093UniSTSGRCm38
MGSCv37664,397,808 - 64,398,087UniSTSGRCm37
Celera666,582,453 - 66,582,732UniSTS
Cytogenetic Map6C1UniSTS
cM Map6 UniSTS
D6Rck360  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38664,465,813 - 64,466,075UniSTSGRCm38
MGSCv37664,415,807 - 64,416,069UniSTSGRCm37
Celera666,600,500 - 66,600,762UniSTS
Cytogenetic Map6C1UniSTS
cM Map6 UniSTS
D6Rck365  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38664,623,051 - 64,623,167UniSTSGRCm38
MGSCv37664,573,045 - 64,573,161UniSTSGRCm37
Celera666,757,864 - 66,757,980UniSTS
Cytogenetic Map6C1UniSTS
cM Map629.67UniSTS
D6Rck362  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38664,485,276 - 64,485,568UniSTSGRCm38
MGSCv37664,435,270 - 64,435,562UniSTSGRCm37
Celera666,619,923 - 66,620,215UniSTS
Cytogenetic Map6C1UniSTS
Cytogenetic Map12F2UniSTS
cM Map6 UniSTS
cM Map1263.25UniSTS
cM Map1260.0UniSTS
Grid2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38664,666,152 - 64,666,247UniSTSGRCm38
MGSCv37664,616,146 - 64,616,241UniSTSGRCm37
Celera666,793,547 - 66,793,642UniSTS
Cytogenetic Map6C1UniSTS
cM Map629.65UniSTS
Grid2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38664,666,053 - 64,666,180UniSTSGRCm38
MGSCv37664,616,047 - 64,616,174UniSTSGRCm37
Celera666,793,448 - 66,793,575UniSTS
Cytogenetic Map6C1UniSTS
cM Map629.65UniSTS
Grid2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map6C1UniSTS
cM Map629.65UniSTS
Grid2  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map6C1UniSTS
cM Map629.65UniSTS


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001370966 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_008167 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036165857 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC093476 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC100383 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC122802 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC122859 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC123852 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC131711 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC134622 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC138621 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC158380 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC162924 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC168092 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AEKQ02073325 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AEKQ02073410 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF110420 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK032669 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK036192 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK036230 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK045348 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK046237 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK141070 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC139823 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466523 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D13266 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000095852   ⟹   ENSMUSP00000093536
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl663,233,011 - 64,645,269 (+)Ensembl
GRCm38.p6 Ensembl663,256,027 - 64,668,285 (+)Ensembl
Ensembl Acc Id: ENSMUST00000159319
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl663,232,860 - 63,291,055 (+)Ensembl
GRCm38.p6 Ensembl663,255,876 - 63,314,071 (+)Ensembl
Ensembl Acc Id: ENSMUST00000159561
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl663,232,990 - 64,159,461 (+)Ensembl
GRCm38.p6 Ensembl663,256,006 - 64,182,477 (+)Ensembl
Ensembl Acc Id: ENSMUST00000160408
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl663,233,179 - 63,481,856 (+)Ensembl
GRCm38.p6 Ensembl663,256,195 - 63,504,872 (+)Ensembl
Ensembl Acc Id: ENSMUST00000161105
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl663,233,810 - 64,255,776 (+)Ensembl
GRCm38.p6 Ensembl663,256,826 - 64,278,792 (+)Ensembl
Ensembl Acc Id: ENSMUST00000162968
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl664,053,776 - 64,071,732 (+)Ensembl
GRCm38.p6 Ensembl664,076,792 - 64,094,748 (+)Ensembl
Ensembl Acc Id: ENSMUST00000210324   ⟹   ENSMUSP00000147707
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl664,640,172 - 64,681,307 (+)Ensembl
GRCm38.p6 Ensembl664,663,188 - 64,704,323 (+)Ensembl
RefSeq Acc Id: NM_001370966   ⟹   NP_001357895
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39663,232,990 - 64,681,305 (+)NCBI
GRCm38663,256,006 - 64,704,321 (+)NCBI
Sequence:
RefSeq Acc Id: NM_008167   ⟹   NP_032193
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39663,232,990 - 64,645,269 (+)NCBI
GRCm38663,256,006 - 64,668,285 (+)NCBI
MGSCv37663,206,851 - 64,616,273 (+)RGD
Celera665,396,130 - 66,793,674 (+)RGD
cM Map6 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_036165857   ⟹   XP_036021750
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39663,230,118 - 64,680,468 (+)NCBI
Sequence:
RefSeq Acc Id: NP_032193   ⟸   NM_008167
- Peptide Label: isoform 1 precursor
- UniProtKB: A4QPG1 (UniProtKB/Swiss-Prot),   Q61625 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001357895   ⟸   NM_001370966
- Peptide Label: isoform 2 precursor
Ensembl Acc Id: ENSMUSP00000147707   ⟸   ENSMUST00000210324
Ensembl Acc Id: ENSMUSP00000093536   ⟸   ENSMUST00000095852
RefSeq Acc Id: XP_036021750   ⟸   XM_036165857
- Peptide Label: isoform X1

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q61625-F1-model_v2 AlphaFold Q61625 1-1007 view protein structure

Promoters
RGD ID:6889884
Promoter ID:EPDNEW_M8393
Type:single initiation site
Name:Grid2_1
Description:Mus musculus glutamate receptor, ionotropic, delta 2 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38663,256,903 - 63,256,963EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:95813 AgrOrtholog
Ensembl Genes ENSMUSG00000071424 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000095852 ENTREZGENE
  ENSMUST00000095852.5 UniProtKB/Swiss-Prot
  ENSMUST00000210324.2 UniProtKB/TrEMBL
Gene3D-CATH 1.10.287.70 UniProtKB/Swiss-Prot
  3.40.50.2300 UniProtKB/Swiss-Prot
  Periplasmic binding protein-like II UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro ANF_lig-bd_rcpt UniProtKB/Swiss-Prot
  Glu/Gly-bd UniProtKB/Swiss-Prot
  Iono_rcpt_met UniProtKB/Swiss-Prot
  Ionotropic_Glu_rcpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Iontro_rcpt UniProtKB/Swiss-Prot
  Peripla_BP_I UniProtKB/Swiss-Prot
KEGG Report mmu:14804 UniProtKB/Swiss-Prot
MGD MGI:95813 ENTREZGENE
NCBI Gene 14804 ENTREZGENE
PANTHER GLUTAMATE RECEPTOR IONOTROPIC, DELTA-2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IONOTROPIC GLUTAMATE RECEPTOR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam ANF_receptor UniProtKB/Swiss-Prot
  Lig_chan UniProtKB/Swiss-Prot
  Lig_chan-Glu_bd UniProtKB/Swiss-Prot
PhenoGen Grid2 PhenoGen
PRINTS NMDARECEPTOR UniProtKB/Swiss-Prot
SMART Lig_chan-Glu_bd UniProtKB/Swiss-Prot
  PBPe UniProtKB/Swiss-Prot
Superfamily-SCOP Periplasmic binding protein-like II UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF53822 UniProtKB/Swiss-Prot
UniProt A0A1B0GRX8_MOUSE UniProtKB/TrEMBL
  A4QPG1 ENTREZGENE
  GRID2_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q8CCJ1_MOUSE UniProtKB/TrEMBL
UniProt Secondary A4QPG1 UniProtKB/Swiss-Prot