Htt (huntingtin) - Rat Genome Database

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Gene: Htt (huntingtin) Mus musculus
Symbol: Htt
Name: huntingtin
RGD ID: 68473
Description: Enables diazepam binding activity. Involved in several processes, including postsynapse to nucleus signaling pathway; regulation of cAMP-dependent protein kinase activity; and regulation of protein localization to nucleus. Acts upstream of or within several processes, including carboxylic acid metabolic process; positive regulation of cilium assembly; and transport along microtubule. Located in several cellular components, including centriole; inclusion body; and perinuclear region of cytoplasm. Is active in glutamatergic synapse. Is expressed in several structures, including central nervous system; olfactory epithelium; peripheral nervous system; retina; and testis. Used to study Huntington's disease. Human ortholog(s) of this gene implicated in Huntington's disease and Parkinson's disease. Orthologous to human HTT (huntingtin).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: AI256365; C430023I11Rik; Hd; HD protein homolog; Hdh; hunti; Huntington disease gene homolog; huntington disease protein homolog; IT1; IT15
RGD Orthologs
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm39534,919,084 - 35,069,878 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl534,919,084 - 35,069,878 (+)EnsemblGRCm39 Ensembl
GRCm38534,761,721 - 34,912,534 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl534,761,740 - 34,912,534 (+)EnsemblGRCm38mm10GRCm38
MGSCv37535,104,389 - 35,252,045 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36535,078,597 - 35,226,253 (+)NCBIMGSCv36mm8
Celera532,235,862 - 32,383,257 (+)NCBICelera
Cytogenetic Map5B2NCBI
cM Map517.92NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (EXP)
17alpha-ethynylestradiol  (EXP)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (ISO)
2,4-dinitrotoluene  (ISO)
2,6-dinitrotoluene  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
aflatoxin B1  (EXP,ISO)
Aflatoxin B2 alpha  (ISO)
ammonium chloride  (ISO)
arsenite(3-)  (ISO)
atrazine  (ISO)
auramine O  (ISO)
Benoxacor  (EXP)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
cadmium atom  (EXP)
cadmium dichloride  (EXP)
caffeine  (ISO)
carbon nanotube  (EXP)
cisplatin  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
coumarin  (ISO)
crocidolite asbestos  (EXP)
cypermethrin  (ISO)
desflurane  (EXP)
dexamethasone  (ISO)
dichlorine  (ISO)
dicrotophos  (ISO)
endosulfan  (ISO)
ethanol  (EXP)
flavonoids  (ISO)
formic acid  (ISO)
gallic acid  (ISO)
geldanamycin  (ISO)
genistein  (ISO)
gentamycin  (ISO)
indometacin  (ISO)
inulin  (EXP)
iron atom  (EXP)
iron(0)  (EXP)
isoflurane  (EXP)
ivermectin  (ISO)
lead diacetate  (EXP)
lead(0)  (ISO)
lead(2+)  (ISO)
lipopolysaccharide  (EXP)
manganese atom  (EXP,ISO)
manganese(0)  (EXP,ISO)
manganese(II) chloride  (EXP)
minocycline  (ISO)
N-ethyl-N-nitrosourea  (ISO)
ozone  (ISO)
p-menthan-3-ol  (ISO)
paracetamol  (ISO)
paraquat  (ISO)
perfluorooctane-1-sulfonic acid  (EXP)
pirinixic acid  (EXP)
pregnenolone 16alpha-carbonitrile  (ISO)
procymidone  (ISO)
sevoflurane  (EXP)
silver atom  (ISO)
silver(0)  (ISO)
Soman  (ISO)
trimellitic anhydride  (EXP)
tungsten  (EXP)
valproic acid  (ISO)
vinclozolin  (ISO)
xestospongin C  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
anatomical structure morphogenesis  (IMP)
anterior/posterior pattern specification  (IMP)
associative learning  (IMP)
axo-dendritic transport  (IMP)
brain development  (IMP)
cellular senescence  (IMP)
central nervous system development  (IMP)
citrulline metabolic process  (IMP)
determination of adult lifespan  (IMP)
dopamine receptor signaling pathway  (IMP)
endoplasmic reticulum organization  (IMP)
endoplasmic reticulum to Golgi vesicle-mediated transport  (IMP)
endosomal transport  (IMP)
establishment of mitotic spindle orientation  (ISO)
gastrulation  (IMP)
Golgi organization  (ISO)
grooming behavior  (IMP)
hormone metabolic process  (IMP)
insulin secretion  (IMP)
lactate biosynthetic process from pyruvate  (IMP)
learning  (IMP)
learning or memory  (IMP)
locomotory behavior  (IMP)
microtubule depolymerization  (ISO)
microtubule-based transport  (IBA)
mitochondrial transport  (IMP)
mitochondrion organization  (IMP)
mRNA transport  (ISO)
multicellular organismal-level iron ion homeostasis  (IMP)
negative regulation of apoptotic process  (IDA,IMP)
negative regulation of cysteine-type endopeptidase activity  (ISO)
negative regulation of extrinsic apoptotic signaling pathway  (ISO)
neural plate formation  (IMP)
neurogenesis  (IMP)
neuron development  (IMP)
olfactory lobe development  (IMP)
paraxial mesoderm formation  (IMP)
peptide hormone secretion  (IMP)
positive regulation of aggrephagy  (ISO)
positive regulation of apoptotic process  (ISO)
positive regulation of autophagy of mitochondrion  (ISO)
positive regulation of cilium assembly  (ISO)
positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity  (ISO)
positive regulation of lipophagy  (ISO)
positive regulation of motile cilium assembly  (IMP)
positive regulation of non-motile cilium assembly  (IMP)
postsynapse to nucleus signaling pathway  (IDA,IEP,IMP)
protein destabilization  (ISO)
protein localization to centrosome  (IMP)
protein localization to nucleus  (IMP)
quinolinate biosynthetic process  (IMP)
regulation of CAMKK-AMPK signaling cascade  (ISO)
regulation of cAMP-dependent protein kinase activity  (IMP,ISO)
regulation of gene expression  (IMP)
regulation of intracellular mRNA localization  (ISO)
regulation of neuron apoptotic process  (IMP)
regulation of phosphoprotein phosphatase activity  (ISO)
regulation of protein localization to nucleus  (IMP)
regulation of synaptic plasticity  (IMP)
response to calcium ion  (IMP)
retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum  (ISO)
social behavior  (IMP)
spermatogenesis  (IMP)
striatum development  (IMP)
urea cycle  (IMP)
vesicle transport along microtubule  (IDA,ISO)
visual learning  (IMP)
vocal learning  (ISO)

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal action potential  (IAGP)
abnormal amniotic cavity morphology  (IAGP)
abnormal anterior commissure morphology  (IAGP)
abnormal behavior  (IAGP)
abnormal blood vessel morphology  (IAGP)
abnormal brain internal capsule morphology  (IAGP)
abnormal brain morphology  (IAGP)
abnormal brain ventricle morphology  (IAGP)
abnormal cell nucleus morphology  (IAGP)
abnormal cell physiology  (IAGP)
abnormal cell proliferation  (IAGP)
abnormal cerebellum development  (IAGP)
abnormal cerebellum lobule morphology  (IAGP)
abnormal cerebral aqueduct morphology  (IAGP)
abnormal cerebral cortex morphology  (IAGP)
abnormal CNS synaptic transmission  (IAGP)
abnormal corpus callosum morphology  (IAGP)
abnormal cranium morphology  (IAGP)
abnormal depression-related behavior  (IAGP)
abnormal developmental patterning  (IAGP)
abnormal dorsal striatum morphology  (IAGP)
abnormal ear position  (IAGP)
abnormal ear shape  (IAGP)
abnormal ectoderm development  (IAGP)
abnormal egg cylinder morphology  (IAGP)
abnormal embryonic tissue morphology  (IAGP)
abnormal embryonic/fetal subventricular zone morphology  (IAGP)
abnormal excitatory postsynaptic currents  (IAGP)
abnormal extraembryonic endoderm formation  (IAGP)
abnormal extraembryonic mesoderm development  (IAGP)
abnormal extraembryonic tissue morphology  (IAGP)
abnormal forebrain morphology  (IAGP)
abnormal gait  (IAGP)
abnormal gastrulation  (IAGP)
abnormal globus pallidus morphology  (IAGP)
abnormal head morphology  (IAGP)
abnormal hippocampus morphology  (IAGP)
abnormal lateral ganglionic eminence morphology  (IAGP)
abnormal lateral ventricle morphology  (IAGP)
abnormal learning/memory/conditioning  (IAGP)
abnormal locomotor activation  (IAGP)
abnormal locomotor coordination  (IAGP)
abnormal male germ cell apoptosis  (IAGP)
abnormal medium spiny neuron morphology  (IAGP)
abnormal midbrain morphology  (IAGP)
abnormal motor capabilities/coordination/movement  (IAGP)
abnormal motor coordination/balance  (IAGP)
abnormal motor learning  (IAGP)
abnormal myelination  (IAGP)
abnormal nervous system development  (IAGP)
abnormal nervous system physiology  (IAGP)
abnormal nervous system tract morphology  (IAGP)
abnormal neuron morphology  (IAGP)
abnormal neuron physiology  (IAGP)
abnormal object recognition memory  (IAGP)
abnormal olfactory bulb morphology  (IAGP)
abnormal olfactory system morphology  (IAGP)
abnormal oligodendrocyte morphology  (IAGP)
abnormal oligodendrocyte physiology  (IAGP)
abnormal postnatal subventricular zone morphology  (IAGP)
abnormal primary motor cortex morphology  (IAGP)
abnormal Reichert's membrane morphology  (IAGP)
abnormal seminiferous tubule morphology  (IAGP)
abnormal spermatid morphology  (IAGP)
abnormal striatum morphology  (IAGP)
abnormal subthalamic nucleus morphology  (IAGP)
abnormal telencephalon morphology  (IAGP)
abnormal thalamus morphology  (IAGP)
abnormal ventral striatum morphology  (IAGP)
abnormal visceral endoderm morphology  (IAGP)
absent hippocampal fimbria  (IAGP)
absent neural folds  (IAGP)
absent primitive node  (IAGP)
absent somites  (IAGP)
astrocytosis  (IAGP)
axon degeneration  (IAGP)
bradykinesia  (IAGP)
brain atrophy  (IAGP)
decreased body size  (IAGP)
decreased body weight  (IAGP)
decreased brain size  (IAGP)
decreased cell proliferation  (IAGP)
decreased embryo size  (IAGP)
decreased excitatory postsynaptic current amplitude  (IAGP)
decreased grip strength  (IAGP)
decreased locomotor activity  (IAGP)
decreased myelin sheath thickness  (IAGP)
decreased neocortex volume  (IAGP)
decreased oligodendrocyte number  (IAGP)
decreased paired-pulse facilitation  (IAGP)
decreased vertical activity  (IAGP)
dilated lateral ventricle  (IAGP)
disorganized embryonic tissue  (IAGP)
disorganized extraembryonic tissue  (IAGP)
domed cranium  (IAGP)
dysmyelination  (IAGP)
ectopic neuron  (IAGP)
embryonic growth arrest  (IAGP)
embryonic growth retardation  (IAGP)
embryonic lethality between implantation and placentation, incomplete penetrance  (IAGP)
embryonic lethality between somite formation and embryo turning, complete penetrance  (IAGP)
embryonic lethality during organogenesis, complete penetrance  (IAGP)
embryonic lethality prior to organogenesis  (IEA)
embryonic lethality, complete penetrance  (IAGP)
embryonic-extraembryonic boundary constriction  (IAGP)
enhanced coordination  (IAGP)
enlarged cerebral aqueduct  (IAGP)
enlarged lateral ventricles  (IAGP)
enlarged third ventricle  (IAGP)
environmentally induced seizures  (IAGP)
exencephaly  (IAGP)
gliosis  (IAGP)
hunched posture  (IAGP)
hydrocephaly  (IAGP)
hyperactivity  (IAGP)
hyperresponsive  (IAGP)
impaired balance  (IAGP)
impaired coordination  (IAGP)
impaired limb coordination  (IAGP)
impaired spatial learning  (IAGP)
impaired synaptic plasticity  (IAGP)
increased aggression towards mice  (IAGP)
increased body weight  (IAGP)
increased cellular sensitivity to alkylating agents  (IAGP)
increased ectoderm apoptosis  (IAGP)
increased embryonic epiblast cell apoptosis  (IAGP)
increased embryonic tissue cell apoptosis  (IAGP)
increased exploration in new environment  (IAGP)
increased grip strength  (IEA)
increased grooming behavior  (IAGP)
increased locomotor activity  (IAGP)
increased Reichert's membrane thickness  (IAGP)
increased stereotypic behavior  (IAGP)
increased susceptibility to malignant hyperthermia  (IAGP)
increased taurine level  (IAGP)
increased thigmotaxis  (IAGP)
increased vertical activity  (IAGP)
lethality throughout fetal growth and development, incomplete penetrance  (IAGP)
limb grasping  (IAGP)
long stride length  (IAGP)
lordokyphosis  (IAGP)
lowered ear position  (IAGP)
male infertility  (IAGP)
microgliosis  (IAGP)
multinucleated giant male germ cells  (IAGP)
muscular atrophy  (IAGP)
neonatal lethality, complete penetrance  (IAGP)
neurodegeneration  (IAGP)
neuron degeneration  (IAGP)
neuronal cytoplasmic inclusions  (IAGP)
neuronal intranuclear inclusions  (IAGP)
no abnormal phenotype detected  (IAGP)
oligozoospermia  (IAGP)
paralysis  (IAGP)
perinatal lethality, complete penetrance  (IAGP)
perinatal lethality, incomplete penetrance  (IAGP)
premature death  (IAGP)
prenatal lethality, complete penetrance  (IAGP)
prenatal lethality, incomplete penetrance  (IAGP)
preweaning lethality, complete penetrance  (IAGP)
reduced long term potentiation  (IAGP)
reduced male fertility  (IAGP)
seizures  (IAGP)
short stride length  (IAGP)
small amniotic cavity  (IAGP)
small testis  (IAGP)
straub tail  (IAGP)
testicular atrophy  (IAGP)
thick skin  (IAGP)
tonic-clonic seizures  (IAGP)
tremors  (IAGP)
weight loss  (IAGP)

References - curated
# Reference Title Reference Citation
1. Therapeutic silencing of mutant huntingtin with siRNA attenuates striatal and cortical neuropathology and behavioral deficits. DiFiglia M, etal., Proc Natl Acad Sci U S A. 2007 Oct 23;104(43):17204-9. Epub 2007 Oct 16.
2. Characterization of a rat model of Huntington's disease based on targeted expression of mutant huntingtin in the forebrain using adeno-associated viral vectors. Gabery S, etal., Eur J Neurosci. 2012 Sep;36(6):2789-800. doi: 10.1111/j.1460-9568.2012.08193.x. Epub 2012 Jun 25.
3. Huntingtin is degraded to small fragments by calpain after ischemic injury. Kim M, etal., Exp Neurol 2003 Sep;183(1):109-15.
4. Differential expression of Huntington's disease gene (IT15) mRNA in developing rat brain. Kumar U Brain Res Mol Brain Res 2004 Sep 10;128(1):39-47.
5. Increased Steady-State Mutant Huntingtin mRNA in Huntington's Disease Brain. Liu W, etal., J Huntingtons Dis. 2013;2(4):491-500. doi: 10.3233/JHD-130079.
6. Comparison between a-synuclein wild-type and A53T mutation in a progressive Parkinson's disease model. Lu J, etal., Biochem Biophys Res Commun. 2015 Sep 4;464(4):988-93. doi: 10.1016/j.bbrc.2015.07.007. Epub 2015 Jul 17.
7. Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice. Mangiarini L, etal., Cell 1996 Nov 1;87(3):493-506.
8. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
9. MGDs mouse GO annotations MGD data from the GO Consortium
11. Targeted disruption of the Huntington's disease gene results in embryonic lethality and behavioral and morphological changes in heterozygotes. Nasir J, etal., Cell 1995 Jun 2;81(5):811-23.
12. Trinucleotide repeat elongation in the Huntingtin gene in Huntington disease patients from 71 Danish families. Norremolle A, etal., Hum Mol Genet. 1993 Sep;2(9):1475-6.
13. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
14. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
15. Mouse MP Annotation Import Pipeline RGD automated import pipeline
16. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
17. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
18. Huntington's disease: from molecular pathogenesis to clinical treatment. Ross CA and Tabrizi SJ, Lancet Neurol. 2011 Jan;10(1):83-98. doi: 10.1016/S1474-4422(10)70245-3.
19. The Biology of Huntingtin. Saudou F and Humbert S, Neuron. 2016 Mar 2;89(5):910-26. doi: 10.1016/j.neuron.2016.02.003.
20. Expression of the Huntington disease gene in rodents: cloning the rat homologue and evidence for downregulation in non-neuronal tissues during development. Schmitt I, etal., Hum Mol Genet 1995 Jul;4(7):1173-82.
21. Transgenic rat model of Huntington's disease. von Hörsten S, etal., Hum Mol Genet. 2003 Mar 15;12(6):617-24.
Additional References at PubMed
PMID:1284592   PMID:7550343   PMID:7618107   PMID:7647777   PMID:7662892   PMID:7759106   PMID:7919654   PMID:7959767   PMID:8009370   PMID:8162057   PMID:8264627   PMID:8401589  
PMID:8757264   PMID:8791525   PMID:8824873   PMID:8845840   PMID:8889548   PMID:8889551   PMID:8968738   PMID:9017261   PMID:9090377   PMID:9246489   PMID:9267033   PMID:9300654  
PMID:9328479   PMID:9398841   PMID:9502734   PMID:9599014   PMID:9605877   PMID:9887339   PMID:9949199   PMID:10037472   PMID:10078572   PMID:10082833   PMID:10098399   PMID:10098889  
PMID:10196365   PMID:10196370   PMID:10196373   PMID:10341082   PMID:10349636   PMID:10353238   PMID:10402204   PMID:10434294   PMID:10434296   PMID:10434303   PMID:10448198   PMID:10464095  
PMID:10533044   PMID:10581038   PMID:10595501   PMID:10632104   PMID:10699173   PMID:10723724   PMID:10739639   PMID:10754231   PMID:10778856   PMID:10799690   PMID:10860780   PMID:10899153  
PMID:10922068   PMID:10932179   PMID:10942430   PMID:11013077   PMID:11030759   PMID:11032906   PMID:11035034   PMID:11042159   PMID:11062468   PMID:11076861   PMID:11092755   PMID:11133364  
PMID:11145989   PMID:11152656   PMID:11152661   PMID:11152662   PMID:11160912   PMID:11217851   PMID:11344337   PMID:11358447   PMID:11442350   PMID:11447996   PMID:11494364   PMID:11520890  
PMID:11567051   PMID:11592850   PMID:11597144   PMID:11606636   PMID:11709539   PMID:11752065   PMID:11788820   PMID:11817536   PMID:11821898   PMID:11880489   PMID:11906693   PMID:11912178  
PMID:11932021   PMID:11971876   PMID:12078510   PMID:12115678   PMID:12217951   PMID:12223581   PMID:12354780   PMID:12456676   PMID:12460551   PMID:12460554   PMID:12466534   PMID:12466851  
PMID:12520002   PMID:12554681   PMID:12588797   PMID:12881483   PMID:12881722   PMID:12895502   PMID:12904583   PMID:12913073   PMID:12926013   PMID:12969257   PMID:14570710   PMID:14610273  
PMID:14962977   PMID:14981075   PMID:15163634   PMID:15190011   PMID:15200234   PMID:15242649   PMID:15340079   PMID:15371500   PMID:15379887   PMID:15496430   PMID:15496672   PMID:15615787  
PMID:15654337   PMID:15749339   PMID:15781041   PMID:15781153   PMID:15829505   PMID:15843620   PMID:15935052   PMID:15983033   PMID:16076956   PMID:16109169   PMID:16141072   PMID:16141073  
PMID:16150600   PMID:16183657   PMID:16230019   PMID:16237181   PMID:16256944   PMID:16278683   PMID:16286508   PMID:16289942   PMID:16403806   PMID:16423528   PMID:16446101   PMID:16487146  
PMID:16522639   PMID:16571604   PMID:16624677   PMID:16687439   PMID:16697652   PMID:16699508   PMID:16750274   PMID:16766198   PMID:16777606   PMID:16820007   PMID:16978870   PMID:17012230  
PMID:17018277   PMID:17055784   PMID:17065224   PMID:17114649   PMID:17124493   PMID:17147801   PMID:17208201   PMID:17213233   PMID:17239451   PMID:17284197   PMID:17291464   PMID:17334227  
PMID:17335925   PMID:17352931   PMID:17394466   PMID:17442827   PMID:17500595   PMID:17519223   PMID:17548833   PMID:17611284   PMID:17704510   PMID:17708681   PMID:17715336   PMID:17868456  
PMID:17947312   PMID:18065495   PMID:18242663   PMID:18288205   PMID:18299573   PMID:18337408   PMID:18367261   PMID:18412970   PMID:18502655   PMID:18504298   PMID:18558632   PMID:18595722  
PMID:18602275   PMID:18615096   PMID:18625318   PMID:18625748   PMID:18640979   PMID:18669659   PMID:18768691   PMID:18799693   PMID:18805465   PMID:18829967   PMID:18838463   PMID:18845944  
PMID:18923047   PMID:18981372   PMID:19036965   PMID:19074039   PMID:19124532   PMID:19144827   PMID:19240033   PMID:19240112   PMID:19264961   PMID:19279257   PMID:19345187   PMID:19445966  
PMID:19464370   PMID:19487684   PMID:19488402   PMID:19498170   PMID:19525941   PMID:19566678   PMID:19602103   PMID:19642201   PMID:19646509   PMID:19666572   PMID:19692612   PMID:19710014  
PMID:19745829   PMID:19825844   PMID:19915593   PMID:19933700   PMID:19955426   PMID:19956633   PMID:19997493   PMID:20018729   PMID:20053912   PMID:20064390   PMID:20086007   PMID:20140187  
PMID:20185558   PMID:20185826   PMID:20354076   PMID:20357106   PMID:20383138   PMID:20403078   PMID:20442398   PMID:20444706   PMID:20457229   PMID:20457230   PMID:20494921   PMID:20497470  
PMID:20519964   PMID:20531388   PMID:20616151   PMID:20668203   PMID:20696378   PMID:20739295   PMID:20945165   PMID:21106706   PMID:21179468   PMID:21184755   PMID:21192926   PMID:21245084  
PMID:21248135   PMID:21267068   PMID:21304966   PMID:21315254   PMID:21336284   PMID:21347256   PMID:21364626   PMID:21403395   PMID:21440047   PMID:21447599   PMID:21454471   PMID:21454633  
PMID:21459327   PMID:21482444   PMID:21505144   PMID:21511013   PMID:21513775   PMID:21536587   PMID:21542802   PMID:21632937   PMID:21636527   PMID:21677750   PMID:21768291   PMID:21785217  
PMID:21832090   PMID:21840924   PMID:21873635   PMID:21896309   PMID:21897851   PMID:21954231   PMID:21969577   PMID:21985783   PMID:21994396   PMID:22001697   PMID:22011578   PMID:22044764  
PMID:22085744   PMID:22116937   PMID:22123819   PMID:22123826   PMID:22178857   PMID:22191580   PMID:22216210   PMID:22327034   PMID:22337954   PMID:22341442   PMID:22355657   PMID:22365050  
PMID:22396390   PMID:22466506   PMID:22492998   PMID:22508027   PMID:22511757   PMID:22512000   PMID:22529362   PMID:22542623   PMID:22556411   PMID:22579526   PMID:22589249   PMID:22649566  
PMID:22794259   PMID:22822065   PMID:22891683   PMID:22892315   PMID:22939619   PMID:22956852   PMID:22956985   PMID:22970194   PMID:22984513   PMID:23001568   PMID:23012356   PMID:23054839  
PMID:23122961   PMID:23145961   PMID:23195593   PMID:23197653   PMID:23209424   PMID:23219902   PMID:23230231   PMID:23251447   PMID:23284626   PMID:23284644   PMID:23300147   PMID:23341618  
PMID:23341638   PMID:23352662   PMID:23365139   PMID:23372043   PMID:23374344   PMID:23469253   PMID:23525043   PMID:23572526   PMID:23598407   PMID:23652004   PMID:23678106   PMID:23691206  
PMID:23774650   PMID:23829302   PMID:23852340   PMID:23861892   PMID:23908352   PMID:23925262   PMID:23936129   PMID:23967334   PMID:23969239   PMID:24019939   PMID:24021477   PMID:24040016  
PMID:24086450   PMID:24105466   PMID:24116161   PMID:24204315   PMID:24278347   PMID:24282028   PMID:24302884   PMID:24347167   PMID:24376631   PMID:24453320   PMID:24594939   PMID:24619418  
PMID:24696705   PMID:24706768   PMID:24706802   PMID:24728190   PMID:24728353   PMID:24749073   PMID:24780625   PMID:24906892   PMID:24946181   PMID:24948797   PMID:24951540   PMID:24955833  
PMID:24960609   PMID:24991961   PMID:24992836   PMID:25004085   PMID:25009276   PMID:25035419   PMID:25057205   PMID:25062858   PMID:25101683   PMID:25143394   PMID:25180603   PMID:25205109  
PMID:25205111   PMID:25368120   PMID:25398949   PMID:25411494   PMID:25446099   PMID:25447230   PMID:25449908   PMID:25461618   PMID:25478910   PMID:25526803   PMID:25540325   PMID:25574027  
PMID:25609071   PMID:25619660   PMID:25645993   PMID:25661181   PMID:25686248   PMID:25738228   PMID:25747711   PMID:25748626   PMID:25760041   PMID:25762686   PMID:25789755   PMID:25859666  
PMID:25866151   PMID:25914140   PMID:25942483   PMID:25989602   PMID:26037141   PMID:26048156   PMID:26141599   PMID:26143143   PMID:26165689   PMID:26195796   PMID:26210937   PMID:26247199  
PMID:26282324   PMID:26293574   PMID:26295712   PMID:26362846   PMID:26419281   PMID:26464483   PMID:26464486   PMID:26546830   PMID:26634350   PMID:26659666   PMID:26660732   PMID:26681807  
PMID:26793080   PMID:26859386   PMID:26900923   PMID:26908599   PMID:26908605   PMID:26908614   PMID:26947127   PMID:26951659   PMID:27008868   PMID:27063456   PMID:27140644   PMID:27147650  
PMID:27147652   PMID:27163546   PMID:27170174   PMID:27196694   PMID:27199664   PMID:27203582   PMID:27217211   PMID:27219491   PMID:27322419   PMID:27334347   PMID:27378694   PMID:27381424  
PMID:27405468   PMID:27463137   PMID:27466181   PMID:27484239   PMID:27486903   PMID:27493027   PMID:27516062   PMID:27525439   PMID:27559163   PMID:27561680   PMID:27568644   PMID:27570076  
PMID:27601642   PMID:27615381   PMID:27623015   PMID:27639545   PMID:27646506   PMID:27701442   PMID:27721240   PMID:27886014   PMID:27913616   PMID:27916455   PMID:27988204   PMID:27989734  
PMID:27995895   PMID:28007908   PMID:28017473   PMID:28031289   PMID:28069792   PMID:28099507   PMID:28104789   PMID:28171658   PMID:28175299   PMID:28194040   PMID:28211815   PMID:28334820  
PMID:28384474   PMID:28384479   PMID:28391067   PMID:28396396   PMID:28453524   PMID:28469074   PMID:28502806   PMID:28550168   PMID:28555636   PMID:28578004   PMID:28628038   PMID:28653853  
PMID:28676743   PMID:28715425   PMID:28729730   PMID:28743452   PMID:28823953   PMID:28847953   PMID:28893927   PMID:28927719   PMID:28930690   PMID:28970536   PMID:28986324   PMID:28993428  
PMID:29162692   PMID:29212017   PMID:29259100   PMID:29274742   PMID:29298414   PMID:29302618   PMID:29324753   PMID:29355642   PMID:29396492   PMID:29430620   PMID:29460266   PMID:29534157  
PMID:29617656   PMID:29688337   PMID:29694882   PMID:29789657   PMID:29843246   PMID:29891550   PMID:29894684   PMID:29912367   PMID:29967375   PMID:30054496   PMID:30061661   PMID:30118496  
PMID:30179155   PMID:30182387   PMID:30193095   PMID:30239724   PMID:30262848   PMID:30282695   PMID:30312396   PMID:30321100   PMID:30323233   PMID:30333137   PMID:30333735   PMID:30365550  
PMID:30449600   PMID:30451892   PMID:30517854   PMID:30587542   PMID:30624705   PMID:30626701   PMID:30742117   PMID:30819797   PMID:30897080   PMID:30913220   PMID:30914652   PMID:30930170  
PMID:30961637   PMID:31015293   PMID:31017573   PMID:31040226   PMID:31060804   PMID:31068790   PMID:31109380   PMID:31132785   PMID:31184975   PMID:31282030   PMID:31375685   PMID:31379510  
PMID:31418857   PMID:31499139   PMID:31666200   PMID:31666698   PMID:31677786   PMID:31695145   PMID:31790427   PMID:31816043   PMID:31875875   PMID:31912442   PMID:31913581   PMID:31920562  
PMID:31968243   PMID:32004439   PMID:32093570   PMID:32144144   PMID:32242231   PMID:32325033   PMID:32436947   PMID:32444599   PMID:32452382   PMID:32513388   PMID:32574176   PMID:32581130  
PMID:32640230   PMID:32681165   PMID:32681824   PMID:32747555   PMID:32820193   PMID:32821928   PMID:32859226   PMID:32869871   PMID:32876667   PMID:32897880   PMID:32913184   PMID:32933349  
PMID:32984817   PMID:32990597   PMID:33086039   PMID:33113354   PMID:33170804   PMID:33238365   PMID:33335120   PMID:33370315   PMID:33441541   PMID:33556538   PMID:33618800   PMID:33674575  
PMID:33907289   PMID:33940179   PMID:34043007   PMID:34128157   PMID:34151850   PMID:34233199   PMID:34239412   PMID:34331233   PMID:34341363   PMID:34390831   PMID:34469738   PMID:34504195  
PMID:34648564   PMID:34793694   PMID:34880223   PMID:34884469   PMID:34884918   PMID:34888656   PMID:35086928   PMID:35238684   PMID:35366418   PMID:35943803   PMID:36029989   PMID:36044851  
PMID:36044862   PMID:36278490   PMID:36640336   PMID:36776123   PMID:36867535   PMID:36967065  


Comparative Map Data
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm39534,919,084 - 35,069,878 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl534,919,084 - 35,069,878 (+)EnsemblGRCm39 Ensembl
GRCm38534,761,721 - 34,912,534 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl534,761,740 - 34,912,534 (+)EnsemblGRCm38mm10GRCm38
MGSCv37535,104,389 - 35,252,045 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36535,078,597 - 35,226,253 (+)NCBIMGSCv36mm8
Celera532,235,862 - 32,383,257 (+)NCBICelera
Cytogenetic Map5B2NCBI
cM Map517.92NCBI
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh3843,074,681 - 3,243,960 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl43,041,363 - 3,243,957 (+)EnsemblGRCh38hg38GRCh38
GRCh3743,076,408 - 3,245,687 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3643,046,206 - 3,215,485 (+)NCBINCBI36Build 36hg18NCBI36
Build 3443,113,411 - 3,282,656NCBI
Celera42,987,658 - 3,157,211 (+)NCBICelera
Cytogenetic Map4p16.3NCBI
HuRef43,014,819 - 3,184,168 (+)NCBIHuRef
CHM1_143,074,471 - 3,243,442 (+)NCBICHM1_1
T2T-CHM13v2.043,073,408 - 3,242,718 (+)NCBIT2T-CHM13v2.0
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
mRatBN7.21475,845,836 - 75,996,094 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1475,845,836 - 75,995,070 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1480,298,810 - 80,447,778 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.01481,539,465 - 81,688,433 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.01477,984,701 - 78,133,668 (-)NCBIRnor_WKY
Rnor_6.01481,105,139 - 81,254,637 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1481,105,139 - 81,254,637 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01481,793,632 - 81,942,093 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41481,490,322 - 81,636,856 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11481,492,926 - 81,639,072 (-)NCBI
Celera1474,771,910 - 74,919,669 (-)NCBICelera
Cytogenetic Map14q21NCBI
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
ChiLan1.0 EnsemblNW_0049555141,906,502 - 2,038,889 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555141,906,189 - 2,042,357 (+)NCBIChiLan1.0ChiLan1.0
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
NHGRI_mPanPan143,344,543 - 3,515,858 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v043,215,081 - 3,388,587 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.143,116,810 - 3,287,644 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl43,128,718 - 3,283,730 (+)Ensemblpanpan1.1panPan2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
CanFam3.1361,076,934 - 61,221,462 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl361,079,904 - 61,330,290 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha363,660,661 - 63,805,148 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0361,552,532 - 61,697,091 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl361,555,965 - 61,697,087 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1361,044,140 - 61,188,581 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0361,248,468 - 61,393,186 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0361,608,204 - 61,752,888 (-)NCBIUU_Cfam_GSD_1.0
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
HiC_Itri_2NW_02440528566,741,409 - 66,966,567 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647720,599,635 - 20,668,265 (-)EnsemblSpeTri2.0
SpeTri2.0 EnsemblNW_00493647720,443,113 - 20,577,071 (-)EnsemblSpeTri2.0
SpeTri2.0NW_00493647720,443,101 - 20,577,167 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
Sscrofa11.1 Ensembl81,809,785 - 1,934,024 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.181,809,768 - 1,934,002 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.281,461,795 - 1,586,182 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Pig Cytomap8pNCBI
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
ChlSab1.12745,493,467 - 45,657,690 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2745,497,352 - 45,657,621 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660511,852,227 - 1,977,171 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
HetGla_female_1.0 EnsemblNW_00462475524,603,490 - 24,729,333 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475524,602,955 - 24,729,584 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Variants in Htt
4181 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1987
Count of miRNA genes:778
Interacting mature miRNAs:1050
Transcripts:ENSMUST00000080036, ENSMUST00000123755, ENSMUST00000135039, ENSMUST00000148953, ENSMUST00000156490
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
15039371Nmrs21_mNAFLD-associated magnetic resonance shift 21 (mouse)5350482337504823Mouse
1301806Actd2_mactivity-distance traveled 2 (mouse)Not determined5538452039384652Mouse
4141207Imrfq1_mimmune response to Factor IX QTL 1 (mouse)Not determined5812411742124239Mouse
1301693Sle6_msystemic lupus erythematosus susceptibility 6 (mouse)Not determined5889069387841837Mouse
1357478Kdnw1_mkidney weight 1 (mouse)Not determined5891594940529869Mouse
14696730Kidlq1_mkidney weight, left QTL 1 (mouse)51356315247563152Mouse
1301685Estq2_mestradiol regulated response QTL 2 (mouse)Not determined51563408449634190Mouse
1300719Iba5_minduction of brown adipocytes 5 (mouse)Not determined52068699354687134Mouse
1301776Skts3_mskin tumor susceptibility 3 (mouse)Not determined52166729555667403Mouse
11537368Hmtb10_mhemostasis and thrombosis 10 (mouse)52210082354500318Mouse
11537367Hmtb11_mhemostasis and thrombosis 11 (mouse)52210082364806579Mouse
11341716Rvfs3_mRift Valley fever susceptibility 3 (mouse)526441234138455402Mouse
1300701Cd8ts1_mCD8 T cell subset 1 (mouse)Not determined52721534861215451Mouse
1301555Alcp10_malcohol preference locus 10 (mouse)Not determined53102427565024480Mouse
1301403Alcp9_malcohol preference locus 9 (mouse)Not determined53102427565024480Mouse
11353827Hplq1_mhot plate latency 1 (mouse)53157045865570458Mouse
4140990Lgq6_mlate growth QTL 6 (mouse)Not determined32133234100777931Mouse
4141219W10q16_mweight 10 weeks QTL 16 (mouse)Not determined32133234100777931Mouse
10043995Hbnr9_mHeligmosomoides bakeri nematode resistance 9 (mouse)Not determined53348866767488876Mouse

Markers in Region
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38534,911,067 - 34,911,262UniSTSGRCm38
MGSCv37535,253,716 - 35,253,911UniSTSGRCm37
Celera532,384,928 - 32,385,123UniSTS
Cytogenetic Map5B2UniSTS
cM Map520.0UniSTS
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38534,790,170 - 34,790,324UniSTSGRCm38
MGSCv37535,132,819 - 35,132,973UniSTSGRCm37
Celera532,264,271 - 32,264,427UniSTS
Cytogenetic Map5B2UniSTS
cM Map5 UniSTS
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38534,790,162 - 34,790,306UniSTSGRCm38
MGSCv37535,132,811 - 35,132,955UniSTSGRCm37
Celera532,264,263 - 32,264,409UniSTS
Cytogenetic Map5B2UniSTS
cM Map5 UniSTS
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38534,912,303 - 34,912,454UniSTSGRCm38
MGSCv37535,254,952 - 35,255,103UniSTSGRCm37
Celera532,386,199 - 32,386,350UniSTS
Cytogenetic Map5B2UniSTS
cM Map520.0UniSTS
Mouse AssemblyChrPosition (strand)SourceJBrowse
MGSCv37535,104,469 - 35,104,609UniSTSGRCm37
Celera532,235,942 - 32,236,082UniSTS
Cytogenetic Map5B2UniSTS
cM Map520.0UniSTS
cM Map520.0UniSTS
cM Map520.0UniSTS
cM Map520.0UniSTS
cM Map520.0UniSTS
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38534,761,820 - 34,761,960UniSTSGRCm38
MGSCv37535,104,469 - 35,104,609UniSTSGRCm37
Celera532,235,942 - 32,236,082UniSTS
Cytogenetic Map5B2UniSTS
cM Map520.0UniSTS
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map5B2UniSTS
cM Map520.0UniSTS



Nucleotide Sequences
RefSeq Transcripts NM_010414 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006503744 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017320683 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_376798 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC133204 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC151669 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AH003368 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK042204 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK049546 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK084575 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK161740 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK164637 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BQ175932 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CF745596 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466524 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L23312 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L23313 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L28827 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U24233 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000080036   ⟹   ENSMUSP00000078945
RefSeq Status:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl534,919,088 - 35,069,878 (+)Ensembl
GRCm38.p6 Ensembl534,761,744 - 34,912,534 (+)Ensembl
RefSeq Acc Id: ENSMUST00000123755
RefSeq Status:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl534,919,105 - 34,972,053 (+)Ensembl
GRCm38.p6 Ensembl534,761,761 - 34,814,709 (+)Ensembl
RefSeq Acc Id: ENSMUST00000124272
RefSeq Status:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl535,043,795 - 35,061,068 (+)Ensembl
GRCm38.p6 Ensembl534,886,451 - 34,903,724 (+)Ensembl
RefSeq Acc Id: ENSMUST00000135039
RefSeq Status:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl535,034,536 - 35,042,322 (+)Ensembl
GRCm38.p6 Ensembl534,877,192 - 34,884,978 (+)Ensembl
RefSeq Acc Id: ENSMUST00000148953
RefSeq Status:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl534,919,084 - 34,979,422 (+)Ensembl
GRCm38.p6 Ensembl534,761,740 - 34,822,078 (+)Ensembl
RefSeq Acc Id: ENSMUST00000156490
RefSeq Status:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl534,964,072 - 34,969,137 (+)Ensembl
GRCm38.p6 Ensembl534,806,728 - 34,811,793 (+)Ensembl
RefSeq Acc Id: ENSMUST00000201613
RefSeq Status:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl534,967,353 - 34,969,623 (+)Ensembl
GRCm38.p6 Ensembl534,810,009 - 34,812,279 (+)Ensembl
RefSeq Acc Id: ENSMUST00000202059
RefSeq Status:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl534,953,132 - 34,955,745 (+)Ensembl
GRCm38.p6 Ensembl534,795,788 - 34,798,401 (+)Ensembl
RefSeq Acc Id: NM_010414   ⟹   NP_034544
RefSeq Status: VALIDATED
Mouse AssemblyChrPosition (strand)Source
GRCm39534,919,084 - 35,069,878 (+)NCBI
GRCm38534,761,740 - 34,912,534 (+)NCBI
MGSCv37535,104,389 - 35,252,045 (+)RGD
Celera532,235,862 - 32,386,430 (+)NCBI
RefSeq Acc Id: XM_006503744   ⟹   XP_006503807
RefSeq Status:
Mouse AssemblyChrPosition (strand)Source
GRCm39534,919,089 - 35,066,743 (+)NCBI
GRCm38534,761,723 - 34,909,402 (+)NCBI
RefSeq Acc Id: XM_017320683   ⟹   XP_017176172
RefSeq Status:
Mouse AssemblyChrPosition (strand)Source
GRCm39534,981,716 - 35,066,743 (+)NCBI
GRCm38534,828,473 - 34,909,402 (+)NCBI
RefSeq Acc Id: XR_376798
RefSeq Status:
Mouse AssemblyChrPosition (strand)Source
GRCm39534,919,085 - 35,055,944 (+)NCBI
GRCm38534,761,721 - 34,886,586 (+)NCBI
Reference Sequences
RefSeq Acc Id: NP_034544   ⟸   NM_010414
- UniProtKB: G3X9H5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006503807   ⟸   XM_006503744
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_017176172   ⟸   XM_017320683
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: ENSMUSP00000078945   ⟸   ENSMUST00000080036

RGD ID:6886486
Promoter ID:EPDNEW_M6694
Type:initiation region
Description:Mus musculus huntingtin , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database,
Experiment Methods:Single-end sequencing.
Mouse AssemblyChrPosition (strand)Source
GRCm38534,761,773 - 34,761,833EPDNEW
RGD ID:6837751
Promoter ID:MM_KWN:41983
SO ACC ID:SO:0000170
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:ENSMUST00000114300,   OTTMUST00000056080,   OTTMUST00000056081,   OTTMUST00000056086,   UC008XDA.1
Mouse AssemblyChrPosition (strand)Source
MGSCv36535,104,031 - 35,104,531 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:96067 AgrOrtholog
Ensembl Genes ENSMUSG00000029104 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000078945 ENTREZGENE
  ENSMUSP00000078945.3 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000080036 ENTREZGENE
  ENSMUST00000080036.3 UniProtKB/TrEMBL
Gene3D-CATH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro ARM-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ARM-type_fold UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Huntingtin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Huntingtin_fam UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Huntingtin_middle-repeat UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:15194 UniProtKB/TrEMBL
  PTHR10170 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam DUF3652 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Htt PhenoGen
Superfamily-SCOP beta-sandwich domain of Sec23/24 UniProtKB/Swiss-Prot
  SSF48371 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL