Epha3 (Eph receptor A3) - Rat Genome Database

Name: Epha3
Creator: Rat Genome Database
License: Creative Commons CC BY 4.0
Keywords: Rat Gene RGD Genome

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Gene: Epha3 (Eph receptor A3) Rattus norvegicus

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Symbol:

Epha3

Name:

Eph receptor A3

RGD ID:

68389

Description:

Predicted to enable GPI-linked ephrin receptor activity; growth factor binding activity; and transmembrane-ephrin receptor activity. Involved in cellular response to interleukin-1; fever generation; and response to lipopolysaccharide. Predicted to be located in several cellular components, including actin cytoskeleton; early endosome; and nucleus. Predicted to be active in several cellular components, including GABA-ergic synapse; dendrite; and presynapse. Human ortholog(s) of this gene implicated in pancreatic cancer. Orthologous to human EPHA3 (EPH receptor A3); PARTICIPATES IN altered ephrin - ephrin receptor bidirectional signaling pathway; ephrin - ephrin receptor bidirectional signaling axis; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; acetamide.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

EK4; EPH-like kinase 4; ephrin type-A receptor 3; rEK4; tyrosine-protein kinase receptor REK4; tyrosine-protein kinase TYRO4

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	EPHA3 (EPH receptor A3)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, Treefam
Mus musculus (house mouse):	Epha3 (Eph receptor A3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Epha3 (EPH receptor A3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	EPHA3 (EPH receptor A3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	EPHA3 (EPH receptor A3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Epha3 (EPH receptor A3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	EPHA3 (EPH receptor A3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	EPHA3 (EPH receptor A3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Epha3 (EPH receptor A3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	EPHA3 (EPH receptor A3)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Epha3 (Eph receptor A3)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	epha3 (eph receptor A3)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|SonicParanoid)
Drosophila melanogaster (fruit fly):	Eph	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	vab-1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	epha3	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	11	14,585,041 - 14,920,721 (-)	NCBI		GRCr8
mRatBN7.2	11	1,138,485 - 1,474,102 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	11	1,140,985 - 1,473,900 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	11	9,737,055 - 10,069,925 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	11	2,530,362 - 2,863,260 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	11	1,635,123 - 1,968,001 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	11	421,253 - 783,037 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	11	421,135 - 782,954 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	11	420,518 - 782,868 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	11	696,185 - 1,033,287 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	11	696,200 - 1,033,287 (-)	NCBI
Celera	11	1,134,161 - 1,466,533 (-)	NCBI		Celera
Cytogenetic Map	11	p12	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

atrial fibrillation (ISO)

Fever (IEP)

pancreatic cancer (ISO)

Spinal Cord Injuries (IEP)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(-)-demecolcine (ISO)

(S)-nicotine (ISO)

1,2-dichloroethane (ISO)

17beta-estradiol (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP)

2,3,7,8-Tetrachlorodibenzofuran (EXP)

2-naphthylamine (ISO)

acetamide (EXP)

acrylamide (ISO)

aldrin (ISO)

all-trans-retinoic acid (ISO)

allethrin (EXP)

alpha-amanitin (ISO)

ammonium chloride (EXP)

antimycin A (ISO)

aristolochic acid A (ISO)

arsenite(3-) (ISO)

atrazine (EXP)

belinostat (ISO)

benzo[a]pyrene (ISO)

bis(2-ethylhexyl) phthalate (EXP)

bisphenol A (EXP)

bucladesine (ISO)

cadmium atom (ISO)

cadmium dichloride (EXP)

cocaine (EXP)

cyhalothrin (EXP)

cypermethrin (EXP)

DDD (ISO)

DDE (ISO)

DDT (ISO)

dibutyl phthalate (EXP)

dieldrin (ISO)

dioxygen (ISO)

diquat (ISO)

dorsomorphin (ISO)

doxorubicin (ISO)

endosulfan (EXP)

endrin (ISO)

entinostat (ISO)

ethyl methanesulfonate (ISO)

fenvalerate (EXP)

folic acid (ISO)

formaldehyde (ISO)

furan (EXP)

gamma-hexachlorocyclohexane (ISO)

genistein (EXP,ISO)

Licochalcone B (ISO)

lipopolysaccharide (ISO)

medroxyprogesterone acetate (ISO)

methoxychlor (EXP)

methyl methanesulfonate (ISO)

methylmercury chloride (ISO)

N,N-diethyl-m-toluamide (EXP)

N-methyl-4-phenylpyridinium (ISO)

nicotine (ISO)

ozone (EXP)

panobinostat (ISO)

permethrin (EXP)

phenylmercury acetate (ISO)

picoxystrobin (ISO)

pioglitazone (ISO)

ponatinib (ISO)

potassium dichromate (ISO)

progesterone (ISO)

pyrethrins (EXP)

rofecoxib (ISO)

rotenone (ISO)

S-(1,2-dichlorovinyl)-L-cysteine (ISO)

SB 431542 (ISO)

silicon dioxide (EXP)

silver atom (ISO)

silver(0) (ISO)

simvastatin (ISO)

sotorasib (ISO)

sunitinib (ISO)

temozolomide (ISO)

tetrachloroethene (ISO)

tetrachloromethane (ISO)

titanium dioxide (ISO)

trametinib (ISO)

trichostatin A (ISO)

triclosan (ISO)

valproic acid (ISO)

XL147 (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

axon guidance (IBA)

brain-derived neurotrophic factor receptor signaling pathway (IEA)

cell migration (ISO,ISS)

cellular response to follicle-stimulating hormone stimulus (ISO)

cellular response to interleukin-1 (IEP)

cellular response to retinoic acid (IEA,ISO)

chromatin remodeling (IEA)

collagen-activated tyrosine kinase receptor signaling pathway (IEA)

endocardial cushion development (ISO)

ephrin receptor signaling pathway (IBA,IEA,ISO,ISS)

epidermal growth factor receptor signaling pathway (IEA)

fasciculation of motor neuron axon (ISO,ISS)

fasciculation of sensory neuron axon (ISO,ISS)

fever generation (IEP)

fibroblast growth factor receptor signaling pathway (IEA)

hepatocyte growth factor receptor signaling pathway (IEA)

insulin receptor signaling pathway (IEA)

insulin-like growth factor receptor signaling pathway (IEA)

Kit signaling pathway (IEA)

macrophage colony-stimulating factor signaling pathway (IEA)

motor neuron axon guidance (ISO)

negative regulation of endocytosis (IEA,ISO)

negative regulation of neuron projection development (ISO)

peptidyl-tyrosine phosphorylation (ISO)

platelet-derived growth factor receptor-alpha signaling pathway (IEA)

platelet-derived growth factor receptor-beta signaling pathway (IEA)

positive regulation of neuron projection development (IEA,ISO)

positive regulation of protein localization to plasma membrane (IEA,ISO)

regulation of actin cytoskeleton organization (IEA,ISO,ISS)

regulation of cell migration (ISO)

regulation of epithelial to mesenchymal transition (ISO,ISS)

regulation of focal adhesion assembly (IEA,ISO,ISS)

regulation of microtubule cytoskeleton organization (IEA,ISO,ISS)

response to lipopolysaccharide (IEP)

synaptic membrane adhesion (ISO)

vascular endothelial growth factor receptor-1 signaling pathway (IEA)

vascular endothelial growth factor signaling pathway (IEA)

Cellular Component

actin cytoskeleton (IEA,ISO)

cytosol (IEA,ISO)

dendrite (IBA)

early endosome (IEA,ISO,ISS)

GABA-ergic synapse (ISO)

nuclear membrane (IEA,ISO)

nucleoplasm (IEA,ISO)

plasma membrane (IBA,IEA,ISO,ISS)

presynapse (ISO)

Molecular Function

ATP binding (IEA)

boss receptor activity (IEA)

brain-derived neurotrophic factor receptor activity (IEA)

ephrin receptor activity (ISO)

epidermal growth factor receptor activity (IEA)

fibroblast growth factor receptor activity (IEA)

GPI-linked ephrin receptor activity (IEA,ISO,ISS)

growth factor binding (ISO)

hepatocyte growth factor receptor activity (IEA)

histone H2AXY142 kinase activity (IEA)

histone H3Y41 kinase activity (IEA)

insulin receptor activity (IEA)

insulin-like growth factor receptor activity (IEA)

macrophage colony-stimulating factor receptor activity (IEA)

placental growth factor receptor activity (IEA)

platelet-derived growth factor alpha-receptor activity (IEA)

platelet-derived growth factor beta-receptor activity (IEA)

protein binding (ISO)

protein tyrosine kinase collagen receptor activity (IEA)

stem cell factor receptor activity (IEA)

transmembrane-ephrin receptor activity (IBA,IEA)

vascular endothelial growth factor receptor activity (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

altered ephrin - ephrin receptor bidirectional signaling pathway (ISS)

ephrin - ephrin receptor bidirectional signaling axis (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Inhibition of VEGF-dependent multistage carcinogenesis by soluble EphA receptors.	Cheng N, etal., Neoplasia. 2003 Sep-Oct;5(5):445-56.
2.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3.	Upregulation of EphA3 receptor after spinal cord injury.	Irizarry-Ramirez M, etal., J Neurotrauma. 2005 Aug;22(8):929-35.
4.	Expression of Eph receptors and their ligands, ephrins, during lipopolysaccharide fever in rats.	Ivanov AI, etal., Physiol Genomics. 2005 Apr 14;21(2):152-60. Epub 2005 Jan 25.
5.	IL-1 beta alters the expression of the receptor tyrosine kinase gene r-EphA3 in neonatal rat cardiomyocytes.	Li YY, etal., Am J Physiol 1998 Jan;274(1 Pt 2):H331-41.
6.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
7.	Expression and function of the Eph A receptors and their ligands ephrins A in the rat thymus.	Munoz JJ, etal., J Immunol 2002 Jul 1;169(1):177-84.
8.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
9.	PID Annotation Import Pipeline	Pipeline to import Pathway Interaction Database annotations from NCI into RGD
10.	GOA pipeline	RGD automated data pipeline
11.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
12.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
13.	Comprehensive gene review and curation	RGD comprehensive gene curation
14.	The role of ephrins and Eph receptors in cancer.	Surawska H, etal., Cytokine Growth Factor Rev 2004 Dec;15(6):419-33.

Additional References at PubMed

PMID:11870224	PMID:11877430	PMID:15145949	PMID:17046737	PMID:17910947	PMID:18403711	PMID:19505147	PMID:21135139	PMID:21791286	PMID:22275477	PMID:23242526	PMID:27721017

Genomics

Comparative Map Data

Epha3
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	11	14,585,041 - 14,920,721 (-)	NCBI		GRCr8
mRatBN7.2	11	1,138,485 - 1,474,102 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	11	1,140,985 - 1,473,900 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	11	9,737,055 - 10,069,925 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	11	2,530,362 - 2,863,260 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	11	1,635,123 - 1,968,001 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	11	421,253 - 783,037 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	11	421,135 - 782,954 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	11	420,518 - 782,868 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	11	696,185 - 1,033,287 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	11	696,200 - 1,033,287 (-)	NCBI
Celera	11	1,134,161 - 1,466,533 (-)	NCBI		Celera
Cytogenetic Map	11	p12	NCBI

EPHA3
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	3	89,107,621 - 89,482,134 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	3	89,107,621 - 89,482,134 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	3	89,156,771 - 89,531,284 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	3	89,239,364 - 89,613,974 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	3	89,239,501 - 89,532,185	NCBI
Celera	3	89,910,744 - 90,285,017 (+)	NCBI		Celera
Cytogenetic Map	3	p11.1	NCBI
HuRef	3	89,169,906 - 89,544,877 (+)	NCBI		HuRef
CHM1_1	3	89,109,505 - 89,484,203 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	3	89,183,660 - 89,558,507 (+)	NCBI		T2T-CHM13v2.0

Epha3
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	16	63,363,895 - 63,684,538 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	16	63,363,897 - 63,684,538 (-)	Ensembl		GRCm39 Ensembl
GRCm38	16	63,543,532 - 63,864,175 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	16	63,543,534 - 63,864,175 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	16	63,545,044 - 63,863,983 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	16	63,487,420 - 63,806,359 (-)	NCBI		MGSCv36	mm8
Celera	16	63,844,890 - 64,154,791 (-)	NCBI		Celera
Cytogenetic Map	16	C1.3	NCBI
cM Map	16	36.49	NCBI

Epha3
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955407	4,138,362 - 4,500,688 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955407	4,135,671 - 4,500,900 (-)	NCBI	ChiLan1.0	ChiLan1.0

EPHA3
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	2	89,283,121 - 89,651,438 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	3	89,287,895 - 89,656,226 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	3	89,261,166 - 89,629,010 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	3	91,369,233 - 91,737,300 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	3	91,369,239 - 91,739,056 (+)	Ensembl	panpan1.1		panPan2

EPHA3
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	33	770,234 - 1,092,063 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	33	769,423 - 1,115,986 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	33	949,355 - 1,298,894 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	33	810,080 - 1,159,494 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	33	810,033 - 1,149,524 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	33	779,847 - 1,129,604 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	33	811,416 - 1,161,165 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	33	1,284,819 - 1,381,967 (+)	NCBI		UU_Cfam_GSD_1.0

Epha3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404971	462,842 - 799,414 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936610	462,853 - 799,364 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936610	462,842 - 799,466 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

EPHA3
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	13	166,592,493 - 166,942,767 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	13	166,592,492 - 166,942,791 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	13	177,406,602 - 177,539,843 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3
Sscrofa10.2	13	177,670,369 - 177,810,115 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

EPHA3
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	22	87,480,220 - 87,840,628 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	22	87,480,126 - 87,838,512 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666041	78,860,955 - 79,218,698 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Epha3
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624789	5,534,121 - 5,922,861 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624789	5,534,011 - 5,925,592 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Epha3
1107 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	35
Count of miRNA genes:	31
Interacting mature miRNAs:	34
Transcripts:	ENSRNOT00000040065
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1300147	Bp187	Blood pressure QTL 187	3.67		arterial blood pressure trait (VT:2000000)	blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)	11	1	69446234	Rat
1598842	Glom10	Glomerulus QTL 10	3.4		kidney glomerulus morphology trait (VT:0005325)	index of glomerular damage (CMO:0001135)	11	1	35331169	Rat
1558659	Tescar1	Testicular tumor resistance QTL 1	3.9		testis integrity trait (VT:0010572)	percentage of study population developing testis tumors during a period of time (CMO:0001261)	11	1041931	66113562	Rat
634341	Bw121	Body weight QTL 121	3.56		abdominal fat pad mass (VT:1000711)	abdominal fat pad weight (CMO:0000088)	11	1	21836709	Rat

Markers in Region

Epha3

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	11	1,140,949 - 1,141,092 (+)	MAPPER	mRatBN7.2
Rnor_6.0	11	423,718 - 423,860	NCBI	Rnor6.0
Rnor_5.0	11	422,983 - 423,125	UniSTS	Rnor5.0
RGSC_v3.4	11	696,150 - 696,292	UniSTS	RGSC3.4
Celera	11	1,134,126 - 1,134,268	UniSTS
Cytogenetic Map	11	p12	UniSTS

UniSTS:498373

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	11	1,161,712 - 1,161,779 (+)	MAPPER	mRatBN7.2
Rnor_6.0	11	444,421 - 444,487	NCBI	Rnor6.0
Rnor_5.0	11	443,716 - 443,782	UniSTS	Rnor5.0
RGSC_v3.4	11	716,927 - 716,993	UniSTS	RGSC3.4
Celera	11	1,154,834 - 1,154,900	UniSTS
Cytogenetic Map	11	p12	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
8	8	49	113	91	90	59	23	59	6	212	92	93	45	60	31

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_031564	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006247976	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006247977	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017597945	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039088234	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039088235	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039088236	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	JAXUCZ010000011	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	U69278	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000040065 ⟹ ENSRNOP00000043263

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	11	1,140,985 - 1,473,900 (-)	Ensembl
Rnor_6.0 Ensembl	11	423,753 - 782,954 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000090197 ⟹ ENSRNOP00000068593

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	11	1,140,985 - 1,459,294 (-)	Ensembl
Rnor_6.0 Ensembl	11	421,135 - 768,644 (-)	Ensembl

RefSeq Acc Id:

NM_031564 ⟹ NP_113752

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	11	14,587,541 - 14,920,425 (-)	NCBI
mRatBN7.2	11	1,140,985 - 1,473,900 (-)	NCBI
Rnor_6.0	11	423,753 - 782,954 (-)	NCBI
Rnor_5.0	11	420,518 - 782,868 (-)	NCBI
RGSC_v3.4	11	696,185 - 1,033,287 (-)	RGD
Celera	11	1,134,161 - 1,466,533 (-)	RGD

Sequence:

show sequence

ATATGCTCCTCTCACTGCCCGGTGCACCAGCAACATGGATTGTCACCTCTCCATCCTCATCCTG
TTCGGCTGCTGCGTCCTCAGCTGCTCCAGGGAACTGAGTCCACAGCCTTCCAACGAAGTTAATC
TACTAGATTCAAAAACGATTCAAGGAGAGCTGGGCTGGATCTCCTACCCATCCCACGGGTGGGA
AGAGATCAGTGGTGTTGATGAGCATTACACACCAATCAGGACTTACCAGGTATGCAATGTCATG
GATCACAGCCAAAATAATTGGCTGAGGACAAACTGGGTGCCGAGAAACTCAGCTCAGAAGATCT
ATGTGGAGCTAAAGTTCACACTGCGGGACTGTAACAGCATTCCATTGGTTTTGGGGACTTGCAA
GGAGACCTTTAACCTGTACTACATGGAGTCTGATGATGATCACGGTGTCAAATTCCTAGAGCAT
CAGTTTACAAAGATTGACACCATTGCCGCTGATGAAAGTTTCACTCAAATGGATCTCGGGGACC
GCATTCTAAAACTCAACACTGAGATTAGAGAAGTGGGACCAGTCAATAAAAAGGGGTTTTATTT
GGCCTTTCAAGATGTTGGTGCTTGTGTTGCCTTGGTGTCTGTGAGAGTGTACTTCAAAAAGTGC
CCATTTACAGTGAAGAATCTGGCTATGTTTCCAGACACAGTGCCCATGGACTCCCAGTCCTTGG
TGGAGGTTAGGGGCTCTTGTGTCAATAATTCCAAGGAGGAGGACCCTCCCAGGATGTACTGCAG
TACAGAAGGTGAATGGCTGGTCCCCATTGGCAAGTGCACCTGCAATGCTGGGTATGAAGAACGA
GGGTTCATATGCCAAGCTTGTCGGCCAGGCTTCTACAAGGCTTTGGATGGTGTTGCCAAGTGTA
CTAAGTGCCCACCACACAGCTCAACCCAAGAAGATGGTTCAATGAACTGCAGGTGTGAGAATAA
TTATTTCCGGGCAGAAAAAGACCCTCCATCCATGGCTTGTACCCGACCTCCATCCGCACCAAGA
AATGTTATCTCTAACATAAATGAGACCTCGGTTATCCTGGACTGGAGCTGGCCCCTGGACACAG
GAGGCCGGAAGGATATTACCTTCAACATCATATGTAAAAAATGTGGGTGGAATGTCAGGCAGTG
CGAGCCATGCAGCCCCAACGTCCGCTTCCTCCCTCGTCAGCTTGGACTCACCAACACCACGGTG
ACAGTGACAGACCTCCTGGCACATACTAACTACACCTTTGAGATTGATGCCATTAATGGAGTGT
CAGAGCTGAGCTCGCCACCGAGACAGTTTGCCGCCGTCAGCATCACAACTAATCAGGCTGCTCC
ATCACCAGTTATGACAATTAAGAAAGATCGGACTTCCAGAAACAGTATCTCTTTATCTTGGCAA
GAACCAGAACATCCAAATGGAATTATACTTGACTACGAGGTCAAATACTATGAAAAGCAGGAGC
AAGAGACGAGTTATACCATTTTGAGGGCAAGAGGCACAAATGTTACTATCAGTAGCCTCAAGCC
AGATACTACTTACGTATTCCAAATCCGAGCTCGAACAGCAGCAGGATACGGAACCAACAGCCGC
AAATTTGAATTTGAAAATAGTCCAGACTCCTTCTCCATCTCTGGTGAGAACAGTCATGTGGTGA
TGATTGCGATTTCAGCTGCTGTGGCCATCATTGTCCTCACTGTTGTCACCTACGTTTTGGTCGG
GAGATTTTGTGGCTATCACAAGTCAAAACACAGTTCAGATGAGAAGCGCCTTCACTTTGGGAAT
GGGCACTTAAGACTTCCAGGTCTCAGGACATATGTTGATCCACATACGTATGAAGACCCTACAC
AAGCAGTTCATGAGTTTGCGAAAGAATTGGATGCCACCAACATAGCCATCGACAAAGTTGTTGG
AGCAGGTGAATTTGGAGAAGTTTGCAGTGGTCGCTTAAAGCTTCCTTCAAAAAAAGAGATTTCA
GTGGCTATCAAGACCCTGAAAGTGGGCTACACGGAGAAGCAGAGGAGAGACTTTCTAGGAGAAG
CAAGCATCATGGGACAGTTTGACCACCCCAACATCATCCGACTGGAAGGAGTTGTCACTAAAAG
TAAGCCAGTGATGATTGTCACAGAATACATGGAGAATGGCTCCCTGGACAGTTTCTTACGTAAA
CATGATGCCCAGTTTACAGTCATCCAGCTCGTGGGAATGCTCCGTGGGATAGCATCTGGTATGA
AGTACCTCTCAGATATGGGCTATGTCCACCGCGACCTTGCTGCTCGAAACATCTTGATCAACAG
TAACTTGGTGTGCAAAGTCTCTGACTTCGGACTTTCTCGAGTGTTGGAAGATGACCCTGAAGCT
GCTTACACCACCAGAGGAGGAAAGATACCAGTAAGGTGGACATCACCAGAAGCAACTGCCTACC
GCAAGTTCACATCAGCCAGCGATGTATGGAGTTACGGGATTGTACTCTGGGAAGTGATGTCTTA
CGGAGAAAGGCCGTATTGGGAGATGTCCAATCAGGATGTTATTAAGGCCGTGGATGAGGGTTAT
CGCCTGCCACTTCCCATGGACTGCCCAGCTGCCCTGTATCAGTTGATGTTGGACTGCTGGCAGA
AAGACAGGAACAACAGACCCAAGTTTGAGCAGATCGTCAGCATTCTGGACAAGCTCATCCGGAA
TCCAGGCAGTCTGAAGATCATCACAAGCGCGGCTGCAAGGCCATCAAACCTTCTTCTGGACCAA
AGCAATGTCGATATTGCTACGTTCCACACAACAGGTGATTGGCTTAACGGTATGAGGACAGCAC
ACTGTAAGGAAATCTTCACGGGTGTGGAGTACAGCTCCTGTGACACCATTGCCAAGATCTCCAC
AGATGACATGAAAAAGGTTGGTGTTACTGTGGTTGGGCCACAGAAGAAGATCATCAGTTCCATT
AAAGCTCTAGAAACACAATCTAAGAATGGTCCAGTTCCCGTGTAAAGTACTGGAAGGATGTGAG
GAAAGGGAAGATGCAGCGTCATCCAGCAAACAGATAGAAATGGTGGAGATGCTGCAGAAGCTCC
AAGTC

hide sequence

RefSeq Acc Id:

XM_006247976 ⟹ XP_006248038

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	11	14,585,041 - 14,920,721 (-)	NCBI
mRatBN7.2	11	1,138,485 - 1,474,100 (-)	NCBI
Rnor_6.0	11	421,253 - 783,037 (-)	NCBI
Rnor_5.0	11	420,518 - 782,868 (-)	NCBI

Sequence:

show sequence

TGACATCAGACTGCGAGCGGAGCATGGTAACTTCTCCAGCAATCAGAGCGCTCTCCCACACATC
AGTGGCATGCTTCGTGGAGATATGCTCCTCTCACTGCCCGGTGCACCAGCAACATGGATTGTCA
CCTCTCCATCCTCATCCTGCTCGGCTGCTGCGTCCTCAGCTGCTCCAGGGAACTGAGTCCACAG
CCTTCCAACGAAGTTAATCTACTAGATTCAAAAACGATTCAAGGAGAGCTGGGCTGGATCTCCT
ACCCATCCCACGGGTGGGAAGAGATCAGTGGTGTTGATGAGCATTACACACCAATCAGGACTTA
CCAGGTATGCAATGTCATGGATCACAGCCAAAATAATTGGCTGAGGACAAACTGGGTGCCGAGA
AACTCAGCTCAGAAGATCTATGTGGAGCTAAAGTTCACACTGCGGGACTGTAACAGCATTCCAT
TGGTTTTGGGGACGTGCAAGGAGACCTTTAACCTGTACTACATGGAGTCTGATGATGATCACGG
TGTCAAATTCCTAGAGCATCAGTTTACAAAGATTGACACCATCGCCGCTGATGAAAGTTTCACT
CAAATGGATCTCGGGGACCGCATTCTAAAACTCAACACTGAGATTAGAGAAGTGGGACCAGTCA
ATAAAAAGGGGTTTTATTTGGCCTTTCAAGATGTTGGTGCTTGTGTTGCCTTGGTGTCTGTGAG
AGTGTACTTCAAAAAGTGCCCATTTACAGTGAAGAATCTGGCTATGTTTCCAGACACAGTGCCC
ATGGACTCCCAGTCCTTGGTGGAGGTTAGGGGCTCTTGTGTCAATAATTCCAAGGAGGAGGACC
CTCCCAGGATGTACTGCAGTACAGAAGGTGAATGGCTGGTCCCCATTGGCAAGTGCACTTGCAA
TGCTGGGTATGAAGAACGAGGGTTCATATGCCAAGCTTGTCGGCCAGGCTTCTACAAGGCTTTG
GATGGTGTTGCCAAGTGTACTAAGTGCCCACCACACAGCTCAACCCAAGAAGATGGTTCAATGA
ACTGCAGGTGTGAGAATAATTATTTCCGGGCAGAAAAAGACCCTCCATCCATGGCTTGTACCCG
ACCTCCATCCGCACCAAGAAATGTTATCTCTAACATAAATGAGACCTCGGTTATCCTGGACTGG
AGCTGGCCCCTGGACACAGGAGGCCGGAAGGATATTACCTTCAACATCATATGTAAAAAATGTG
GGTGGAATGTCAGGCAGTGCGAGCCATGCAGCCCCAACGTCCGCTTCCTCCCTCGTCAGCTTGG
ACTCACCAACACCACGGTGACAGTGACAGACCTCCTGGCACATACTAACTACACCTTTGAGATT
GATGCCATTAATGGAGTGTCAGAGCTGAGCTCGCCACCGAGACAGTTTGCCGCCGTCAGCATCA
CAACTAATCAGGCTGCTCCATCACCAGTTATGACAATTAAGAAAGATCGGACTTCCAGAAACAG
TATCTCTTTATCTTGGCAAGAACCAGAACATCCAAATGGAATTATACTTGACTACGAGGTCAAA
TACTATGAAAAGGAGCAAGAGACGAGTTATACCATTTTGAGGGCAAGAGGCACAAATGTTACTA
TCAGTAGCCTCAAGCCAGATACTACTTACGTATTCCAAATCCGAGCTCGAACAGCAGCAGGATA
CGGAACCAACAGCCGCAAATTTGAATTTGAAACTAGTCCAGACTCCTTCTCCATCTCTGGTGAA
AACAGTCATGTGGTGATGATCGCGATTTCAGCTGCTGTGGCCATCATTGTCCTCACTGTTGTCA
CCTACGTTTTGGTCGGGAGATTTTGTGGCTATCACAAGTCAAAACACAGTTCAGATGAGAAGCG
CCTTCACTTTGGGAATGGGCACTTAAGACTTCCAGGTCTCAGGACATATGTTGATCCACATACA
TATGAAGACCCTACACAAGCAGTTCATGAGTTTGCGAAAGAATTGGATGCCACCAACATAGCCA
TCGACAAAGTTGTTGGAGCAGGTGAATTTGGAGAAGTTTGCAGTGGTCGCTTAAAACTTCCTTC
AAAAAAAGAGATTTCAGTGGCTATCAAGACCCTGAAAGTGGGCTACACGGAGAAGCAGAGGAGA
GACTTTCTAGGAGAAGCAAGCATCATGGGACAGTTTGACCACCCCAACATCATCCGACTGGAAG
GAGTTGTCACTAAAAGTAAGCCAGTGATGATTGTCACAGAATACATGGAGAATGGTTCCCTGGA
CAGTTTCTTACGTAAACATGATGCCCAGTTTACAGTCATCCAGCTCGTGGGAATGCTCCGTGGG
ATAGCATCTGGTATGAAGTACCTCTCAGATATGGGCTATGTCCACCGCGACCTTGCTGCTCGGA
ACATCTTGATCAACAGTAACTTGGTGTGCAAAGTCTCTGACTTCGGACTTTCTCGAGTGTTGGA
AGATGACCCTGAAGCTGCTTACACCACCAGAGGAGGAAAGATACCAATAAGGTGGACATCACCA
GAAGCAATTGCCTACCGCAAGTTCACATCAGCCAGCGATGTATGGAGTTACGGGATTGTACTCT
GGGAAGTGATGTCTTACGGAGAAAGGCCGTATTGGGAGATGTCCAATCAGGATGTAATTAAGGC
CGTGGATGAGGGCTATCGCCTGCCACCTCCCATGGACTGCCCAGCTGCCCTGTATCAGTTGATG
TTGGACTGCTGGCAGAAAGACAGGAACAACAGACCCAAGTTTGAGCAGATCGTCAGCATTCTGG
ACAAGCTCATCCGGAATCCAGGCAGTCTGAAGATCATCACTAGCGCGGCTGCAAGGCCATCAAA
CCTTCTTCTGGACCAAAGCAATGTCGATATTGCTACGTTCCACACAACAGGTGATTGGCTTAAC
GGTATGAGGACAGCACACTGTAAGGAAATCTTCACGGGTGTGGAGTACAGCTCCTGTGACACCA
TTGCCAAGATCTCCACAGATGACATGAAAAAGGTTGGTGTTACTGTGGTTGGGCCACAGAAGAA
GATCATCAGTTCCATTAAAGCTCTAGAAACACAATCTAAGAATGGTCCAGTTCCCGTGTAAAGT
ACTGGAAGGATGTGAGGAAAGGGAAGATGCAGCGTCATCCAGCAAACAGATAGAAATGGTGGAG
CTGCTGCTGAAAGCTCCAAGTCTAACAAGACACTCAGTTATAAGTCCAAATGCCTTAAAAATGG
AATTGAAAAATCTCTTTATTTTCCCTTATCATTTTACGTGTGGGTGGGTGGGTGCATTTTGTTT
TGTAACTGCTTTTTAAATGTTAATTGATGGGGTTAATTAAAATTCTTCAGTAAAAAATGGAAGA
ACTAGAGTAGAGCCGTTGATCATTAACTGCCATGGAAGTAAACGAAGTAAACTAGCAAAACGGA
CCTGAAGGCTTTGTTGTGAATGCCCACAGAGGAAAAGACTTGTGATATTTTTATACACAGAAGA
AAATCTGTAACAGGTATTTTGTTTCTTTAAAAGCAAGCAAGATAGAGACATTTATACCTCAAAC
TATCTGGCCATATTTACTATCTTATCACTTTAGTATTCTCTTTATCTATTTGAAGCATATAGAG
ATGAAGTTTGTAGTTGTTTTAAATACTATACATTTTTAATTGTTACCTTCTTAAGTATACCATG
TAAAAACATGTCTTAGTTTGGGGGGAAGTGCATATTTATTTTTCTTTTACATTTTTTATTGTTC
TATATTTATGCCTCGATGATTTAATTTGGGTTTTGTTACAGCCAAGTGCCAAATACTATTGCAA
ATTGTCAGCAGTAAGAAACATGTTTAGCAAGACCCAGAGAATATGTTCTTTTATAGAACTGGTA
AAGAATCCTCTTACATGCACCAACAAAATGAAATGCTTTCCCTGTTCATACAGTCACCAACTCA
CTCACAGTCTGAATTATCCCATTCATTTCTGTCTCTTCATTTATCAGTAACTGTATGCTCCTAA
TTTAGTGTAATATACTGGCTTGTATGCAATAGATTTTTACCCAGATGTCATACCTTCCTTACTC
TGGTGCTTAGAGGGACATCAACTCCTTTCATTCATGAAAGAAGCTTGTTAGAACTTCTTAGATT
TGCAAACTGGAAAGATCAAAATGAAGTTAAATGGTTACAGTAATTGACAGCAGCCTATAGATAA
ATGCATGAGCAAAAAAGAAAGAAAGGAAGAAAAAGTGCTTGTTTTGAATAGTCTTTTAATATCA
TTGCTTAAACGTGTAGAGAATGTTGATAGCTAAGCTACTCATCTGCATCACTGGGGTGTAGGTC
AATTAATTACACACCTTCATCATCAATGTCAGGTATAACTATCTTTGAGTCTTCCACTTCAATG
TATCTATTGTGATTTAGGTACTTTGAATTTCTAATCATATTATTAAATATTATATTTGAAAATA
GCAACTCATCTAGCCAATAAATCCACACCTGCAGACAATGGAGAAATGAGATGTCTCATTATGG
GAATGTAGACTTGCTGTTTCTTTCCTAAAGGCCAATTATGAACATGTTCATTAATATTAAGAAG
GATGTCCCTAATGGGCATTCGTATGACCATACATGCTGAAGATGTATGTGGATTTTCTTACTGA
TAGTACCATACCATAGGATCAAGGAATGCACAGAATAAGATGGTTCAAACAATGCTGTATGAGA
TGTGTCTATATACAATATAGGATACTAAAGAAATCCAGGTTCCAATTATAGAGAACATTTTTCA
AATGATAATCTGTTGTAGGTTTAGTATACTAGAGCTTATGTGAATTCTTTCAGATGTGAAATTG
TTTCCCAAATTTTGGCAATGCTCCTTATAACCCAATCATGCTACTAGAACTTGTATTCAACTTA
TAAGAGCATGAAAATTTTGGAAATGAGCCAATGAAACTAAACTTAAATTTTGCTTATATCTCCT
GAAAGCAGGTAGAAAATACTCTAGTCAAGTAATTTACAATTTGGAATATTTGGTTAAAATTCAA
ATCTGATATCTGTAACAATTTACCTTTAACAGTGTTCACTCTCTAAGGCAATATTCCGAACAAC
CTCAACAATAACAAATTTCAAAATAAGTAGATATTGAAAATGGTTAAATCTGTTGCATTTGTTT
TGGCTTGAGTTTGTTGTTGTTGTTGTTTGAATGTATATGTGGTTTAAATAGCACATTGCTCTTC
ATTTGTCAGGATTTCTTCTATCTTGCCATTTATGAATTTCCTTTGCATAACCCCTTCCCTGTAC
ATATGTAAACATAACAGTGTACGATTCTGGACTGGGGAGTAGAGGTACTAGAATGCTTATGGCC
ATCTCTTTGTATAGGAACTACATTGCTGTCCCATGTCAATGAGGCTACCGCTCCCTTGCCGTGT
TATGTACCATATTACCTGACTTGTATCTTAAATTTGATTTATAGATATTATTTATTTCTCGCAA
CACACCCAGTCAAGGCTGTACTAAGTATCCATCAAGCCATGTATAAATATGATACAATTGGCAG
TATGTGTTTACTTTACACTTGCATTTTTAAAAACATGGTTCATTTAGTTTATGTTGCACAATGT
AGATGGCCTCTTACTAATGTAAAATGATTTCTAGTGGGAACACTTATATTTTTATAATAAACAT
AATGAAAATATTTTTACAGATCGGAA

hide sequence

RefSeq Acc Id:

XM_006247977 ⟹ XP_006248039

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	11	14,585,041 - 14,905,844 (-)	NCBI
mRatBN7.2	11	1,138,485 - 1,459,324 (-)	NCBI
Rnor_6.0	11	421,253 - 769,783 (-)	NCBI
Rnor_5.0	11	420,518 - 782,868 (-)	NCBI

Sequence:

show sequence

ATTATTTAAATAAACATTTTATCTAGAAATCTGAGAATTAGTCTTAACTAAATATTTATATGAC
AACACATACATTAAATTTAACATAAGTTTCTGAGAAGTTTACATGCAAAAGATTTGCTATATAA
TAATCAAAATAGTTTATAGTATCACAACATTTTAGCAGTTGTTAGTTGAAGCACAGCATCTATC
AAAATTGTTATGTTTAGAAAGATACAAAATTACTATCACGTACCCCAAAGAAGCATTTAAATTA
AGATGTAAAAATAATAGATAAGTTCAACTTGAGGTATATCAAAGTAGACTCTTCTAAATTTCTT
TTCAATGGACTATCACACAAACAAACTAGGGGGGAAAGCTGAACTATTGTTAACTTTTGCTCAA
AATATAAATTGTGAATTTTTAATTCCATATTATTTATGAAAGAGAGCTACACAGAGATTTACAA
GAGCAAGAATAAAATGTGTCCCCTTCCGTGTCTTTTTCTTCTGTCTGGGCTGCTTAACTATCAT
TTAGAAGCAGATTATAGGGTTCTTCTGGTCTCTGTAACCTAAACCAAGCGTGTGCTCTTTATCA
TAAAAGAAAGTGATGAAAACGATAAAGATAAGTGGACAAGAAATGTGGCTTGTGTAACCGAGGT
GTTGATGTGAACAGAGTGAAAGTCATTATTCTTTAGTCAAAGCAAGAGGGAATGAAAAGATGGT
CTTCTCTTCAGTTGTGATTTTATAGGCATTTGTATTGGCTATAAAGGCCGCTTATAAGTGAAGG
CTTTACAAGAAAATGTCTATTATTATAGGAATCTGAAATGCTTTAGCTATTATAGCTGCTTGTC
CACTTTGAAATGATTATTTGATAATTATAAATAACTCAATATTTCCATGCAATGAAAACCTTTT
GTCACCACAAAGTGTATTTGATACACTACTAGACAATTGTAAAGATCTGCCTCTGGAAGAGAGT
GTGTGATTGAATTTTTACAGTTTTAACACTGTTTGTACATAGCACTTAATGTGTCCAGTTGTTA
ATATTAGGTTAACTGCCAACCTTTGTAAATGAGCAAGAAGTCATTCTAGATCAGAAGTTAAATT
GTCCTTGAAAAAAAAAGTTCATGTATTCATGGGTTTTAAAGAGTGGAATCTCCAGAGACTTACA
TCACTCGATTTTAATTATCCACATATCTGACATTATCTATTTTAACATTTGATTCTAATACCTG
CATTTTTGAGCCTAGAAATGTAACTCAGTGATACAATACTTCCCTAGCTTGTGTGAGACCTTGA
AATCTAAAGTCTGTAAAACAAAAAATGAGTGGATACAAGGAGGTCTTTTGATAGAAAATTTGAT
GCATTTCTATTAATAAGAGTAGATAGGGCCAATTCTTTGTGATGTCATAAATGAACTCATTTAT
GATGTTGAGGAACAAATCCTGGGCCTCATGGAACCACCATGGAGATATCTCTCTGGCCTGGAAG
AAAATTTTGATTGAATATCTCCTTTGGGACAGACGGTAGAAGAAGGAAAAGAATGGTGGCCACA
AGGAGTCCCAAGTCAACTGTTCAGTGCAGTGGAAGTGTGACAGTCAAATTAGAGGCAGGGGTAA
CAGTTAATCTACTAGATTCAAAAACGATTCAAGGAGAGCTGGGCTGGATCTCCTACCCATCCCA
CGGGTGGGAAGAGATCAGTGGTGTTGATGAGCATTACACACCAATCAGGACTTACCAGGTATGC
AATGTCATGGATCACAGCCAAAATAATTGGCTGAGGACAAACTGGGTGCCGAGAAACTCAGCTC
AGAAGATCTATGTGGAGCTAAAGTTCACACTGCGGGACTGTAACAGCATTCCATTGGTTTTGGG
GACGTGCAAGGAGACCTTTAACCTGTACTACATGGAGTCTGATGATGATCACGGTGTCAAATTC
CTAGAGCATCAGTTTACAAAGATTGACACCATCGCCGCTGATGAAAGTTTCACTCAAATGGATC
TCGGGGACCGCATTCTAAAACTCAACACTGAGATTAGAGAAGTGGGACCAGTCAATAAAAAGGG
GTTTTATTTGGCCTTTCAAGATGTTGGTGCTTGTGTTGCCTTGGTGTCTGTGAGAGTGTACTTC
AAAAAGTGCCCATTTACAGTGAAGAATCTGGCTATGTTTCCAGACACAGTGCCCATGGACTCCC
AGTCCTTGGTGGAGGTTAGGGGCTCTTGTGTCAATAATTCCAAGGAGGAGGACCCTCCCAGGAT
GTACTGCAGTACAGAAGGTGAATGGCTGGTCCCCATTGGCAAGTGCACTTGCAATGCTGGGTAT
GAAGAACGAGGGTTCATATGCCAAGCTTGTCGGCCAGGCTTCTACAAGGCTTTGGATGGTGTTG
CCAAGTGTACTAAGTGCCCACCACACAGCTCAACCCAAGAAGATGGTTCAATGAACTGCAGGTG
TGAGAATAATTATTTCCGGGCAGAAAAAGACCCTCCATCCATGGCTTGTACCCGACCTCCATCC
GCACCAAGAAATGTTATCTCTAACATAAATGAGACCTCGGTTATCCTGGACTGGAGCTGGCCCC
TGGACACAGGAGGCCGGAAGGATATTACCTTCAACATCATATGTAAAAAATGTGGGTGGAATGT
CAGGCAGTGCGAGCCATGCAGCCCCAACGTCCGCTTCCTCCCTCGTCAGCTTGGACTCACCAAC
ACCACGGTGACAGTGACAGACCTCCTGGCACATACTAACTACACCTTTGAGATTGATGCCATTA
ATGGAGTGTCAGAGCTGAGCTCGCCACCGAGACAGTTTGCCGCCGTCAGCATCACAACTAATCA
GGCTGCTCCATCACCAGTTATGACAATTAAGAAAGATCGGACTTCCAGAAACAGTATCTCTTTA
TCTTGGCAAGAACCAGAACATCCAAATGGAATTATACTTGACTACGAGGTCAAATACTATGAAA
AGCAGGAGCAAGAGACGAGTTATACCATTTTGAGGGCAAGAGGCACAAATGTTACTATCAGTAG
CCTCAAGCCAGATACTACTTACGTATTCCAAATCCGAGCTCGAACAGCAGCAGGATACGGAACC
AACAGCCGCAAATTTGAATTTGAAACTAGTCCAGACTCCTTCTCCATCTCTGGTGAAAACAGTC
ATGTGGTGATGATCGCGATTTCAGCTGCTGTGGCCATCATTGTCCTCACTGTTGTCACCTACGT
TTTGGTCGGGAGATTTTGTGGCTATCACAAGTCAAAACACAGTTCAGATGAGAAGCGCCTTCAC
TTTGGGAATGGGCACTTAAGACTTCCAGGTCTCAGGACATATGTTGATCCACATACATATGAAG
ACCCTACACAAGCAGTTCATGAGTTTGCGAAAGAATTGGATGCCACCAACATAGCCATCGACAA
AGTTGTTGGAGCAGGTGAATTTGGAGAAGTTTGCAGTGGTCGCTTAAAACTTCCTTCAAAAAAA
GAGATTTCAGTGGCTATCAAGACCCTGAAAGTGGGCTACACGGAGAAGCAGAGGAGAGACTTTC
TAGGAGAAGCAAGCATCATGGGACAGTTTGACCACCCCAACATCATCCGACTGGAAGGAGTTGT
CACTAAAAGTAAGCCAGTGATGATTGTCACAGAATACATGGAGAATGGTTCCCTGGACAGTTTC
TTACGTAAACATGATGCCCAGTTTACAGTCATCCAGCTCGTGGGAATGCTCCGTGGGATAGCAT
CTGGTATGAAGTACCTCTCAGATATGGGCTATGTCCACCGCGACCTTGCTGCTCGGAACATCTT
GATCAACAGTAACTTGGTGTGCAAAGTCTCTGACTTCGGACTTTCTCGAGTGTTGGAAGATGAC
CCTGAAGCTGCTTACACCACCAGAGGAGGAAAGATACCAATAAGGTGGACATCACCAGAAGCAA
TTGCCTACCGCAAGTTCACATCAGCCAGCGATGTATGGAGTTACGGGATTGTACTCTGGGAAGT
GATGTCTTACGGAGAAAGGCCGTATTGGGAGATGTCCAATCAGGATGTAATTAAGGCCGTGGAT
GAGGGCTATCGCCTGCCACCTCCCATGGACTGCCCAGCTGCCCTGTATCAGTTGATGTTGGACT
GCTGGCAGAAAGACAGGAACAACAGACCCAAGTTTGAGCAGATCGTCAGCATTCTGGACAAGCT
CATCCGGAATCCAGGCAGTCTGAAGATCATCACTAGCGCGGCTGCAAGGCCATCAAACCTTCTT
CTGGACCAAAGCAATGTCGATATTGCTACGTTCCACACAACAGGTGATTGGCTTAACGGTATGA
GGACAGCACACTGTAAGGAAATCTTCACGGGTGTGGAGTACAGCTCCTGTGACACCATTGCCAA
GATCTCCACAGATGACATGAAAAAGGTTGGTGTTACTGTGGTTGGGCCACAGAAGAAGATCATC
AGTTCCATTAAAGCTCTAGAAACACAATCTAAGAATGGTCCAGTTCCCGTGTAAAGTACTGGAA
GGATGTGAGGAAAGGGAAGATGCAGCGTCATCCAGCAAACAGATAGAAATGGTGGAGCTGCTGC
TGAAAGCTCCAAGTCTAACAAGACACTCAGTTATAAGTCCAAATGCCTTAAAAATGGAATTGAA
AAATCTCTTTATTTTCCCTTATCATTTTACGTGTGGGTGGGTGGGTGCATTTTGTTTTGTAACT
GCTTTTTAAATGTTAATTGATGGGGTTAATTAAAATTCTTCAGTAAAAAATGGAAGAACTAGAG
TAGAGCCGTTGATCATTAACTGCCATGGAAGTAAACGAAGTAAACTAGCAAAACGGACCTGAAG
GCTTTGTTGTGAATGCCCACAGAGGAAAAGACTTGTGATATTTTTATACACAGAAGAAAATCTG
TAACAGGTATTTTGTTTCTTTAAAAGCAAGCAAGATAGAGACATTTATACCTCAAACTATCTGG
CCATATTTACTATCTTATCACTTTAGTATTCTCTTTATCTATTTGAAGCATATAGAGATGAAGT
TTGTAGTTGTTTTAAATACTATACATTTTTAATTGTTACCTTCTTAAGTATACCATGTAAAAAC
ATGTCTTAGTTTGGGGGGAAGTGCATATTTATTTTTCTTTTACATTTTTTATTGTTCTATATTT
ATGCCTCGATGATTTAATTTGGGTTTTGTTACAGCCAAGTGCCAAATACTATTGCAAATTGTCA
GCAGTAAGAAACATGTTTAGCAAGACCCAGAGAATATGTTCTTTTATAGAACTGGTAAAGAATC
CTCTTACATGCACCAACAAAATGAAATGCTTTCCCTGTTCATACAGTCACCAACTCACTCACAG
TCTGAATTATCCCATTCATTTCTGTCTCTTCATTTATCAGTAACTGTATGCTCCTAATTTAGTG
TAATATACTGGCTTGTATGCAATAGATTTTTACCCAGATGTCATACCTTCCTTACTCTGGTGCT
TAGAGGGACATCAACTCCTTTCATTCATGAAAGAAGCTTGTTAGAACTTCTTAGATTTGCAAAC
TGGAAAGATCAAAATGAAGTTAAATGGTTACAGTAATTGACAGCAGCCTATAGATAAATGCATG
AGCAAAAAAGAAAGAAAGGAAGAAAAAGTGCTTGTTTTGAATAGTCTTTTAATATCATTGCTTA
AACGTGTAGAGAATGTTGATAGCTAAGCTACTCATCTGCATCACTGGGGTGTAGGTCAATTAAT
TACACACCTTCATCATCAATGTCAGGTATAACTATCTTTGAGTCTTCCACTTCAATGTATCTAT
TGTGATTTAGGTACTTTGAATTTCTAATCATATTATTAAATATTATATTTGAAAATAGCAACTC
ATCTAGCCAATAAATCCACACCTGCAGACAATGGAGAAATGAGATGTCTCATTATGGGAATGTA
GACTTGCTGTTTCTTTCCTAAAGGCCAATTATGAACATGTTCATTAATATTAAGAAGGATGTCC
CTAATGGGCATTCGTATGACCATACATGCTGAAGATGTATGTGGATTTTCTTACTGATAGTACC
ATACCATAGGATCAAGGAATGCACAGAATAAGATGGTTCAAACAATGCTGTATGAGATGTGTCT
ATATACAATATAGGATACTAAAGAAATCCAGGTTCCAATTATAGAGAACATTTTTCAAATGATA
ATCTGTTGTAGGTTTAGTATACTAGAGCTTATGTGAATTCTTTCAGATGTGAAATTGTTTCCCA
AATTTTGGCAATGCTCCTTATAACCCAATCATGCTACTAGAACTTGTATTCAACTTATAAGAGC
ATGAAAATTTTGGAAATGAGCCAATGAAACTAAACTTAAATTTTGCTTATATCTCCTGAAAGCA
GGTAGAAAATACTCTAGTCAAGTAATTTACAATTTGGAATATTTGGTTAAAATTCAAATCTGAT
ATCTGTAACAATTTACCTTTAACAGTGTTCACTCTCTAAGGCAATATTCCGAACAACCTCAACA
ATAACAAATTTCAAAATAAGTAGATATTGAAAATGGTTAAATCTGTTGCATTTGTTTTGGCTTG
AGTTTGTTGTTGTTGTTGTTTGAATGTATATGTGGTTTAAATAGCACATTGCTCTTCATTTGTC
AGGATTTCTTCTATCTTGCCATTTATGAATTTCCTTTGCATAACCCCTTCCCTGTACATATGTA
AACATAACAGTGTACGATTCTGGACTGGGGAGTAGAGGTACTAGAATGCTTATGGCCATCTCTT
TGTATAGGAACTACATTGCTGTCCCATGTCAATGAGGCTACCGCTCCCTTGCCGTGTTATGTAC
CATATTACCTGACTTGTATCTTAAATTTGATTTATAGATATTATTTATTTCTCGCAACACACCC
AGTCAAGGCTGTACTAAGTATCCATCAAGCCATGTATAAATATGATACAATTGGCAGTATGTGT
TTACTTTACACTTGCATTTTTAAAAACATGGTTCATTTAGTTTATGTTGCACAATGTAGATGGC
CTCTTACTAATGTAAAATGATTTCTAGTGGGAACACTTATATTTTTATAATAAACATAATGAAA
ATATTTTTACAGATCGGAA

hide sequence

RefSeq Acc Id:

XM_039088234 ⟹ XP_038944162

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	11	14,585,041 - 14,920,618 (-)	NCBI
mRatBN7.2	11	1,138,485 - 1,474,102 (-)	NCBI

RefSeq Acc Id:

XM_039088235 ⟹ XP_038944163

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	11	14,585,041 - 14,905,723 (-)	NCBI
mRatBN7.2	11	1,138,485 - 1,459,191 (-)	NCBI

RefSeq Acc Id:

XM_039088236 ⟹ XP_038944164

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	11	14,585,041 - 14,844,711 (-)	NCBI
mRatBN7.2	11	1,138,485 - 1,398,187 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_113752	(Get FASTA)	NCBI Sequence Viewer
	XP_006248038	(Get FASTA)	NCBI Sequence Viewer
	XP_006248039	(Get FASTA)	NCBI Sequence Viewer
	XP_038944162	(Get FASTA)	NCBI Sequence Viewer
	XP_038944163	(Get FASTA)	NCBI Sequence Viewer
	XP_038944164	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAC06273	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000043263.2
	ENSRNOP00000068593.1
GenBank Protein	O08680	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_113752 ⟸ NM_031564
- Peptide Label:	precursor
- UniProtKB:	O08680 (UniProtKB/Swiss-Prot), G3V9D5 (UniProtKB/TrEMBL), A6K4V7 (UniProtKB/TrEMBL)
- Sequence:	show sequence MDCHLSILILFGCCVLSCSRELSPQPSNEVNLLDSKTIQGELGWISYPSHGWEEISGVDEHYTP IRTYQVCNVMDHSQNNWLRTNWVPRNSAQKIYVELKFTLRDCNSIPLVLGTCKETFNLYYMESD DDHGVKFLEHQFTKIDTIAADESFTQMDLGDRILKLNTEIREVGPVNKKGFYLAFQDVGACVAL VSVRVYFKKCPFTVKNLAMFPDTVPMDSQSLVEVRGSCVNNSKEEDPPRMYCSTEGEWLVPIGK CTCNAGYEERGFICQACRPGFYKALDGVAKCTKCPPHSSTQEDGSMNCRCENNYFRAEKDPPSM ACTRPPSAPRNVISNINETSVILDWSWPLDTGGRKDITFNIICKKCGWNVRQCEPCSPNVRFLP RQLGLTNTTVTVTDLLAHTNYTFEIDAINGVSELSSPPRQFAAVSITTNQAAPSPVMTIKKDRT SRNSISLSWQEPEHPNGIILDYEVKYYEKQEQETSYTILRARGTNVTISSLKPDTTYVFQIRAR TAAGYGTNSRKFEFENSPDSFSISGENSHVVMIAISAAVAIIVLTVVTYVLVGRFCGYHKSKHS SDEKRLHFGNGHLRLPGLRTYVDPHTYEDPTQAVHEFAKELDATNIAIDKVVGAGEFGEVCSGR LKLPSKKEISVAIKTLKVGYTEKQRRDFLGEASIMGQFDHPNIIRLEGVVTKSKPVMIVTEYME NGSLDSFLRKHDAQFTVIQLVGMLRGIASGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGL SRVLEDDPEAAYTTRGGKIPVRWTSPEATAYRKFTSASDVWSYGIVLWEVMSYGERPYWEMSNQ DVIKAVDEGYRLPLPMDCPAALYQLMLDCWQKDRNNRPKFEQIVSILDKLIRNPGSLKIITSAA ARPSNLLLDQSNVDIATFHTTGDWLNGMRTAHCKEIFTGVEYSSCDTIAKISTDDMKKVGVTVV GPQKKIISSIKALETQSKNGPVPV hide sequence

RefSeq Acc Id:	XP_006248038 ⟸ XM_006247976
- Peptide Label:	isoform X1
- UniProtKB:	O08680 (UniProtKB/Swiss-Prot)
- Sequence:	show sequence MDCHLSILILLGCCVLSCSRELSPQPSNEVNLLDSKTIQGELGWISYPSHGWEEISGVDEHYTP IRTYQVCNVMDHSQNNWLRTNWVPRNSAQKIYVELKFTLRDCNSIPLVLGTCKETFNLYYMESD DDHGVKFLEHQFTKIDTIAADESFTQMDLGDRILKLNTEIREVGPVNKKGFYLAFQDVGACVAL VSVRVYFKKCPFTVKNLAMFPDTVPMDSQSLVEVRGSCVNNSKEEDPPRMYCSTEGEWLVPIGK CTCNAGYEERGFICQACRPGFYKALDGVAKCTKCPPHSSTQEDGSMNCRCENNYFRAEKDPPSM ACTRPPSAPRNVISNINETSVILDWSWPLDTGGRKDITFNIICKKCGWNVRQCEPCSPNVRFLP RQLGLTNTTVTVTDLLAHTNYTFEIDAINGVSELSSPPRQFAAVSITTNQAAPSPVMTIKKDRT SRNSISLSWQEPEHPNGIILDYEVKYYEKEQETSYTILRARGTNVTISSLKPDTTYVFQIRART AAGYGTNSRKFEFETSPDSFSISGENSHVVMIAISAAVAIIVLTVVTYVLVGRFCGYHKSKHSS DEKRLHFGNGHLRLPGLRTYVDPHTYEDPTQAVHEFAKELDATNIAIDKVVGAGEFGEVCSGRL KLPSKKEISVAIKTLKVGYTEKQRRDFLGEASIMGQFDHPNIIRLEGVVTKSKPVMIVTEYMEN GSLDSFLRKHDAQFTVIQLVGMLRGIASGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLS RVLEDDPEAAYTTRGGKIPIRWTSPEAIAYRKFTSASDVWSYGIVLWEVMSYGERPYWEMSNQD VIKAVDEGYRLPPPMDCPAALYQLMLDCWQKDRNNRPKFEQIVSILDKLIRNPGSLKIITSAAA RPSNLLLDQSNVDIATFHTTGDWLNGMRTAHCKEIFTGVEYSSCDTIAKISTDDMKKVGVTVVG PQKKIISSIKALETQSKNGPVPV hide sequence

RefSeq Acc Id:	XP_006248039 ⟸ XM_006247977
- Peptide Label:	isoform X2
- UniProtKB:	O08680 (UniProtKB/Swiss-Prot), A0A0G2JT71 (UniProtKB/TrEMBL)
- Sequence:	show sequence MVATRSPKSTVQCSGSVTVKLEAGVTVNLLDSKTIQGELGWISYPSHGWEEISGVDEHYTPIRT YQVCNVMDHSQNNWLRTNWVPRNSAQKIYVELKFTLRDCNSIPLVLGTCKETFNLYYMESDDDH GVKFLEHQFTKIDTIAADESFTQMDLGDRILKLNTEIREVGPVNKKGFYLAFQDVGACVALVSV RVYFKKCPFTVKNLAMFPDTVPMDSQSLVEVRGSCVNNSKEEDPPRMYCSTEGEWLVPIGKCTC NAGYEERGFICQACRPGFYKALDGVAKCTKCPPHSSTQEDGSMNCRCENNYFRAEKDPPSMACT RPPSAPRNVISNINETSVILDWSWPLDTGGRKDITFNIICKKCGWNVRQCEPCSPNVRFLPRQL GLTNTTVTVTDLLAHTNYTFEIDAINGVSELSSPPRQFAAVSITTNQAAPSPVMTIKKDRTSRN SISLSWQEPEHPNGIILDYEVKYYEKQEQETSYTILRARGTNVTISSLKPDTTYVFQIRARTAA GYGTNSRKFEFETSPDSFSISGENSHVVMIAISAAVAIIVLTVVTYVLVGRFCGYHKSKHSSDE KRLHFGNGHLRLPGLRTYVDPHTYEDPTQAVHEFAKELDATNIAIDKVVGAGEFGEVCSGRLKL PSKKEISVAIKTLKVGYTEKQRRDFLGEASIMGQFDHPNIIRLEGVVTKSKPVMIVTEYMENGS LDSFLRKHDAQFTVIQLVGMLRGIASGMKYLSDMGYVHRDLAARNILINSNLVCKVSDFGLSRV LEDDPEAAYTTRGGKIPIRWTSPEAIAYRKFTSASDVWSYGIVLWEVMSYGERPYWEMSNQDVI KAVDEGYRLPPPMDCPAALYQLMLDCWQKDRNNRPKFEQIVSILDKLIRNPGSLKIITSAAARP SNLLLDQSNVDIATFHTTGDWLNGMRTAHCKEIFTGVEYSSCDTIAKISTDDMKKVGVTVVGPQ KKIISSIKALETQSKNGPVPV hide sequence

Ensembl Acc Id:

ENSRNOP00000068593 ⟸ ENSRNOT00000090197

Ensembl Acc Id:

ENSRNOP00000043263 ⟸ ENSRNOT00000040065

RefSeq Acc Id:	XP_038944162 ⟸ XM_039088234
- Peptide Label:	isoform X3
- UniProtKB:	O08680 (UniProtKB/Swiss-Prot)

RefSeq Acc Id:	XP_038944163 ⟸ XM_039088235
- Peptide Label:	isoform X4
- UniProtKB:	O08680 (UniProtKB/Swiss-Prot)

RefSeq Acc Id:	XP_038944164 ⟸ XM_039088236
- Peptide Label:	isoform X4
- UniProtKB:	O08680 (UniProtKB/Swiss-Prot)

Protein Domains

Eph LBD Fibronectin type-III Protein kinase SAM

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-O08680-F1-model_v2	AlphaFold	O08680	1-984	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:68389	AgrOrtholog
BioCyc Gene	G2FUF-22331	BioCyc
Ensembl Genes	ENSRNOG00000030285	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000040065.3	UniProtKB/TrEMBL
	ENSRNOT00000090197.2	UniProtKB/TrEMBL
Gene3D-CATH	1.10.150.50	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	2.60.40.10	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	ephrin a2 ectodomain	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Galactose-binding domain-like	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Transferase(Phosphotransferase) domain 1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Tumor Necrosis Factor Receptor, subunit A, domain 2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro	Eph_TM	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	EphA3_rcpt_lig-bd	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Ephrin_rcpt_lig-bd_dom	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Ephrin_rcpt_TKs	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	FN3_dom	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	FN3_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Galactose-bd-like_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Growth_fac_rcpt_cys_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Ig-like_fold	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Kinase-like_dom_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Prot_kinase_dom	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Protein_kinase_ATP_BS	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	SAM	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	SAM/pointed_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Ser-Thr/Tyr_kinase_cat_dom	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Tyr-kin_ephrin_A/B_rcpt-like	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Tyr_kinase_AS	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Tyr_kinase_cat_dom	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Tyr_kinase_ephrin_rcpt	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Tyr_kinase_rcpt_V_CS	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	rno:29210	UniProtKB/Swiss-Prot
NCBI Gene	29210	ENTREZGENE
PANTHER	EPH RECEPTOR A5	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	EPHRIN TYPE-A RECEPTOR 3	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	EphA2_TM	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Ephrin_lbd	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Ephrin_rec_like	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	fn3	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Pkinase_Tyr	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	SAM_2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Epha3	PhenoGen
PIRSF	TyrPK_ephrin_receptor	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PRINTS	FNTYPEIII	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	TYRKINASE	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE	EGF_2	UniProtKB/Swiss-Prot
	EPH_LBD	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	FN3	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PROTEIN_KINASE_ATP	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PROTEIN_KINASE_DOM	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PROTEIN_KINASE_TYR	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	RECEPTOR_TYR_KIN_V_1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	RECEPTOR_TYR_KIN_V_2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	SAM_DOMAIN	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000030285	RatGTEx
SMART	EPH_lbd	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Ephrin_rec_like	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	FN3	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	SAM	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	TyrKc	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP	SSF47769	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	SSF49265	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	SSF49785	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	SSF56112	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	SSF57184	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	A0A0G2JT71	ENTREZGENE, UniProtKB/TrEMBL
	A6K4V7	ENTREZGENE, UniProtKB/TrEMBL
	EPHA3_RAT	UniProtKB/Swiss-Prot
	G3V9D5	ENTREZGENE, UniProtKB/TrEMBL
	O08680	ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2002-06-10	Epha3	Eph receptor A3			Name updated	70584	APPROVED

RGD Curation Notes

Note Type	Note	Reference
gene_expression	expressed in leukemia cells, thymocytes from the subcapsulary region, cortex, and medulla and in epithelial cells of the thymic medulla	625721
gene_homology	aa sequence for predicted gene shares 90-98% homology with human EPHA3, chick EphA3, and mouse EphA3	68243

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - CTD

RGD Manual Annotations

Imported Annotations - PID (archival)

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Imported Disease Annotations - CTD

RGD Manual Annotations

Imported Annotations - PID (archival)