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Gene: Mbl2 (mannose binding lectin 2) Rattus norvegicus
Symbol: Mbl2
Name: mannose binding lectin 2
RGD ID: 67380
Description: Exhibits several functions, including identical protein binding activity; monosaccharide binding activity; and phosphatidylinositol-4-phosphate binding activity. Involved in positive regulation of complement activation and positive regulation of protein processing. Localizes to extracellular space and protein-containing complex. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); bacterial infectious disease (multiple); fungal infectious disease (multiple); liver disease (multiple); and lung disease (multiple). Orthologous to human MBL2 (mannose binding lectin 2); PARTICIPATES IN lectin complement pathway; coagulation cascade pathway; complement system pathway; INTERACTS WITH (+)-schisandrin B; (S)-amphetamine; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
Also known as: Ab2-001; Ab2-011; mannan-binding protein; mannose binding lectin 2 (protein C); mannose-binding lectin (protein C) 2; mannose-binding protein C; mannose-binding protein C (liver); MBP-C; RA-reactive factor P28A subunit; ra-reactive factor polysaccharide-binding component p28A; raRF p28A; RARF/P28A
Homo sapiens (human) : MBL2 (mannose binding lectin 2)  HGNC  Alliance
Mus musculus (house mouse) : Mbl2 (mannose-binding lectin (protein C) 2)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mbl2 (mannose binding lectin 2)
Pan paniscus (bonobo/pygmy chimpanzee) : MBL2 (mannose binding lectin 2)
Canis lupus familiaris (dog) : MBL2 (mannose binding lectin 2)
Sus scrofa (pig) : MBL2 (mannose binding lectin 2)
Chlorocebus sabaeus (African green monkey) : MBL2 (mannose binding lectin 2)
Heterocephalus glaber (naked mole-rat) : Mbl2 (mannose binding lectin 2)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01248,435,069 - 248,442,669 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1248,723,397 - 248,729,962 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01255,681,084 - 255,688,683 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41233,978,931 - 233,983,824 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11234,140,682 - 234,147,846 (+)NCBI
Celera1225,160,772 - 225,165,665 (+)NCBICelera
Cytogenetic Map1q52NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Mbl2
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 67380
Created: 2001-06-01
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.