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Gene: Bbip1 (BBSome interacting protein 1) Rattus norvegicus
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Symbol:
Bbip1
Name:
BBSome interacting protein 1
RGD ID:
6498801
Description:
Predicted to be involved in cilium assembly and receptor localization to non-motile cilium. Predicted to act upstream of or within several processes, including B cell homeostasis; eating behavior; and erythrocyte homeostasis. Predicted to be located in ciliary membrane and cytoplasm. Predicted to be part of BBSome. Human ortholog(s) of this gene implicated in Bardet-Biedl syndrome 18. Orthologous to human BBIP1 (BBSome interacting protein 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; amphetamine; bisphenol A.
Type:
protein-coding
RefSeq Status:
VALIDATED
Previously known as:
BBSome-interacting protein 1; BBSome-interacting protein 1-like; LOC100910342
RGD Orthologs
Alliance Orthologs
More Info
more info ...
More Info
Latest Assembly:
GRCr8 - GRCr8 Assembly
Position:
Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 1 262,950,459 - 262,964,410 (-) NCBI GRCr8 GRCr8 GRCr8 GRCr8 Ensembl 1 262,950,462 - 262,964,394 (-) Ensembl GRCr8 mRatBN7.2 1 252,943,589 - 252,959,512 (-) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 1 252,945,557 - 252,959,352 (-) Ensembl mRatBN7.2 UTH_Rnor_SHR_Utx 1 261,134,632 - 261,148,578 (-) NCBI UTH_Rnor_SHR_Utx UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 1 267,840,708 - 267,854,654 (-) NCBI UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 1 260,496,059 - 260,510,012 (-) NCBI UTH_Rnor_WKY_Bbb_1.0 UTH_Rnor_WKY_Bbb_1.0 Rnor_6.0 1 274,649,085 - 274,663,544 (-) NCBI Rnor_6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 1 274,649,490 - 274,650,363 (-) Ensembl rn6 Rnor6.0 Rnor_5.0 1 282,062,613 - 282,076,973 (-) NCBI Rnor_5.0 Rnor_5.0 rn5 Celera 1 248,659,494 - 248,673,953 (-) NCBI Celera Cytogenetic Map 1 q55 NCBI
JBrowse:
Imported Disease Annotations - ClinVar
Imported Disease Annotations - CTD
Imported Disease Annotations - MGI
Imported Disease Annotations - OMIM
Only show annotations with direct experimental evidence (0 objects hidden)
Bbip1 Rat 1,2-dimethylhydrazine decreases expression ISO Bbip1 (Mus musculus) 6480464 1,2-Dimethylhydrazine results in decreased expression of BBIP1 mRNA CTD PMID:22206623 Bbip1 Rat 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO BBIP1 (Homo sapiens) 6480464 [Tetrachlorodibenzodioxin co-treated with 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide] results in increased expression of BBIP1 mRNA CTD PMID:29704546 Bbip1 Rat 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of BBIP1 mRNA CTD PMID:33387578 Bbip1 Rat 3-isobutyl-1-methyl-7H-xanthine multiple interactions ISO BBIP1 (Homo sapiens) 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] more ... CTD PMID:28628672 Bbip1 Rat 4,4'-sulfonyldiphenol increases expression ISO Bbip1 (Mus musculus) 6480464 bisphenol S results in increased expression of BBIP1 mRNA CTD PMID:39298647 Bbip1 Rat aflatoxin B1 decreases methylation ISO BBIP1 (Homo sapiens) 6480464 Aflatoxin B1 results in decreased methylation of BBIP1 gene CTD PMID:27153756 Bbip1 Rat amphetamine increases expression EXP 6480464 Amphetamine results in increased expression of BBIP1 mRNA CTD PMID:30779732 Bbip1 Rat antirheumatic drug decreases expression ISO BBIP1 (Homo sapiens) 6480464 Antirheumatic Agents results in decreased expression of BBIP1 mRNA CTD PMID:24449571 Bbip1 Rat aristolochic acid A decreases expression ISO BBIP1 (Homo sapiens) 6480464 aristolochic acid I results in decreased expression of BBIP1 mRNA CTD PMID:33212167 Bbip1 Rat benzo[a]pyrene diol epoxide I decreases expression ISO BBIP1 (Homo sapiens) 6480464 7,8-Dihydro-7,8-dihydroxybenzo(a)pyrene 9,10-oxide results in decreased expression of BBIP1 mRNA CTD PMID:20018196 Bbip1 Rat bisphenol A multiple interactions ISO BBIP1 (Homo sapiens) 6480464 [bisphenol A co-treated with Fulvestrant] results in increased methylation of BBIP1 gene; [INS protein co-treated more ... CTD PMID:28628672|PMID:31601247 Bbip1 Rat bisphenol A multiple interactions EXP 6480464 [bisphenol A co-treated with tributyltin] results in increased expression of BBIP1 mRNA CTD PMID:31129395 Bbip1 Rat bisphenol F multiple interactions ISO BBIP1 (Homo sapiens) 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] more ... CTD PMID:28628672 Bbip1 Rat bisphenol F decreases expression ISO Bbip1 (Mus musculus) 6480464 bisphenol F results in decreased expression of BBIP1 mRNA CTD PMID:38685157 Bbip1 Rat cadmium dichloride decreases expression ISO BBIP1 (Homo sapiens) 6480464 Cadmium Chloride results in decreased expression of BBIP1 mRNA CTD PMID:38382870 Bbip1 Rat cadmium dichloride increases expression ISO BBIP1 (Homo sapiens) 6480464 Cadmium Chloride results in increased expression of BBIP1 mRNA CTD PMID:38174414 Bbip1 Rat copper atom multiple interactions ISO BBIP1 (Homo sapiens) 6480464 [NSC 689534 binds to Copper] which results in increased expression of BBIP1 mRNA CTD PMID:20971185 Bbip1 Rat copper(0) multiple interactions ISO BBIP1 (Homo sapiens) 6480464 [NSC 689534 binds to Copper] which results in increased expression of BBIP1 mRNA CTD PMID:20971185 Bbip1 Rat cyclosporin A increases expression ISO BBIP1 (Homo sapiens) 6480464 Cyclosporine results in increased expression of BBIP1 mRNA CTD PMID:21632981 Bbip1 Rat dexamethasone multiple interactions ISO BBIP1 (Homo sapiens) 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] more ... CTD PMID:28628672 Bbip1 Rat Dibutyl phosphate affects expression ISO BBIP1 (Homo sapiens) 6480464 di-n-butylphosphoric acid affects the expression of BBIP1 mRNA CTD PMID:37042841 Bbip1 Rat dorsomorphin multiple interactions ISO BBIP1 (Homo sapiens) 6480464 [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression more ... CTD PMID:27188386 Bbip1 Rat entinostat multiple interactions ISO BBIP1 (Homo sapiens) 6480464 [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression more ... CTD PMID:27188386 Bbip1 Rat entinostat decreases expression ISO BBIP1 (Homo sapiens) 6480464 entinostat results in decreased expression of BBIP1 mRNA CTD PMID:26272509 Bbip1 Rat formaldehyde increases expression ISO BBIP1 (Homo sapiens) 6480464 Formaldehyde results in increased expression of BBIP1 mRNA CTD PMID:23649840 Bbip1 Rat fulvestrant multiple interactions ISO BBIP1 (Homo sapiens) 6480464 [bisphenol A co-treated with Fulvestrant] results in increased methylation of BBIP1 gene CTD PMID:31601247 Bbip1 Rat indometacin multiple interactions ISO BBIP1 (Homo sapiens) 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] more ... CTD PMID:28628672 Bbip1 Rat N-methyl-4-phenylpyridinium increases expression ISO BBIP1 (Homo sapiens) 6480464 1-Methyl-4-phenylpyridinium results in increased expression of BBIP1 mRNA CTD PMID:24810058 Bbip1 Rat nickel atom decreases expression ISO BBIP1 (Homo sapiens) 6480464 Nickel results in decreased expression of BBIP1 mRNA CTD PMID:25583101 Bbip1 Rat nitrates multiple interactions ISO Bbip1 (Mus musculus) 6480464 [Particulate Matter results in increased abundance of Nitrates] which results in increased expression of BBIP1 more ... CTD PMID:35964746 Bbip1 Rat paracetamol increases expression ISO BBIP1 (Homo sapiens) 6480464 Acetaminophen results in increased expression of BBIP1 mRNA CTD PMID:21420995 Bbip1 Rat paracetamol increases expression EXP 6480464 Acetaminophen results in increased expression of BBIP1 mRNA CTD PMID:33387578 Bbip1 Rat SB 431542 multiple interactions ISO BBIP1 (Homo sapiens) 6480464 [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression more ... CTD PMID:27188386 Bbip1 Rat sodium arsenate decreases expression ISO Bbip1 (Mus musculus) 6480464 sodium arsenate results in decreased expression of BBIP1 mRNA CTD PMID:30953684 Bbip1 Rat sunitinib increases expression ISO BBIP1 (Homo sapiens) 6480464 Sunitinib results in increased expression of BBIP1 mRNA CTD PMID:31533062 Bbip1 Rat tetrachloromethane affects expression ISO Bbip1 (Mus musculus) 6480464 Carbon Tetrachloride affects the expression of BBIP1 mRNA CTD PMID:17484886 Bbip1 Rat thimerosal increases expression ISO BBIP1 (Homo sapiens) 6480464 Thimerosal results in increased expression of BBIP1 mRNA CTD PMID:27188386 Bbip1 Rat thiram increases expression ISO BBIP1 (Homo sapiens) 6480464 Thiram results in increased expression of BBIP1 mRNA CTD PMID:38568856 Bbip1 Rat tributylstannane multiple interactions EXP 6480464 [bisphenol A co-treated with tributyltin] results in increased expression of BBIP1 mRNA CTD PMID:31129395 Bbip1 Rat trichostatin A decreases expression ISO BBIP1 (Homo sapiens) 6480464 trichostatin A results in decreased expression of BBIP1 mRNA CTD PMID:26272509 Bbip1 Rat trichostatin A multiple interactions ISO BBIP1 (Homo sapiens) 6480464 [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ... CTD PMID:27188386 Bbip1 Rat triphenyl phosphate affects expression ISO BBIP1 (Homo sapiens) 6480464 triphenyl phosphate affects the expression of BBIP1 mRNA CTD PMID:37042841 Bbip1 Rat valproic acid affects expression ISO BBIP1 (Homo sapiens) 6480464 Valproic Acid affects the expression of BBIP1 mRNA CTD PMID:25979313 Bbip1 Rat valproic acid decreases methylation ISO BBIP1 (Homo sapiens) 6480464 Valproic Acid results in decreased methylation of BBIP1 gene CTD PMID:29154799 Bbip1 Rat valproic acid decreases expression ISO BBIP1 (Homo sapiens) 6480464 Valproic Acid results in decreased expression of BBIP1 mRNA CTD PMID:23179753|PMID:24935251|PMID:26272509|PMID:28001369 Bbip1 Rat valproic acid multiple interactions ISO BBIP1 (Homo sapiens) 6480464 [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased more ... CTD PMID:27188386
QTLs in Region (GRCr8)
1354580 Scort1 Serum corticosterone level QTL 1 3.4 blood corticosterone amount (VT:0005345) blood corticosterone level (CMO:0001172) 1 154961463 266453731 Rat 634313 Niddm43 Non-insulin dependent diabetes mellitus QTL 43 blood glucose amount (VT:0000188) blood glucose level (CMO:0000046) 1 208479811 269633915 Rat 1354646 Kidm18 Kidney mass QTL 18 5.7 kidney mass (VT:0002707) calculated kidney weight (CMO:0000160) 1 160573753 266453731 Rat 70211 Niddm24 Non-insulin dependent diabetes mellitus QTL 24 3.79 blood glucose amount (VT:0000188) blood glucose level area under curve (AUC) (CMO:0000350) 1 224633915 269633915 Rat 724552 Glom2 Glomerulus QTL 2 3.3 0.0001 kidney glomerulus morphology trait (VT:0005325) count of superficial glomeruli directly contacting the kidney surface (CMO:0001001) 1 232312773 270518180 Rat 1354652 Kidm20 Kidney mass QTL 20 4.3 kidney mass (VT:0002707) calculated kidney weight (CMO:0000160) 1 186658830 266453731 Rat 61327 Eae7 Experimental allergic encephalomyelitis QTL 7 5.6 body mass (VT:0001259) change in body weight (CMO:0002045) 1 226175591 270518180 Rat 1578775 Iddm21 Insulin dependent diabetes mellitus QTL 21 4.13 blood glucose amount (VT:0000188) blood glucose level (CMO:0000046) 1 245782829 270518180 Rat 1600395 Niddm69 Non-insulin dependent diabetes mellitus QTL 69 4.14 0.0002 blood insulin amount (VT:0001560) plasma insulin level (CMO:0000342) 1 205233991 267096252 Rat 1578763 Kidm29 Kidney mass QTL 29 3.3 0.0001 kidney mass (VT:0002707) both kidneys wet weight (CMO:0000085) 1 218829748 263829748 Rat 1354624 Cm35 Cardiac mass QTL35 5.7 heart left ventricle mass (VT:0007031) calculated heart weight (CMO:0000073) 1 186658830 266453731 Rat 1600396 Niddm68 Non-insulin dependent diabetes mellitus QTL 68 4.97 0.0003 blood glucose amount (VT:0000188) blood glucose level area under curve (AUC) (CMO:0000350) 1 205233991 267096252 Rat 631837 Niddm35 Non-insulin dependent diabetes mellitus QTL 35 0.01 blood insulin amount (VT:0001560) serum insulin level (CMO:0000358) 1 248619887 269633915 Rat 1600397 Edcs4 Endometrial carcinoma susceptibility QTL 4 2.2 uterus morphology trait (VT:0001120) percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759) 1 176288899 270518180 Rat 631836 Stl31 Serum triglyceride level QTL 31 4.64 5e-06 blood triglyceride amount (VT:0002644) plasma triglyceride level (CMO:0000548) 1 247133834 270518180 Rat 1549837 Hcar15 Hepatocarcinoma resistance QTL 15 0.05 liver integrity trait (VT:0010547) liver tumorous lesion number (CMO:0001068) 1 162548015 270518180 Rat 1600388 Niddm67 Non-insulin dependent diabetes mellitus QTL 67 5.84 0.000004 blood glucose amount (VT:0000188) blood glucose level area under curve (AUC) (CMO:0000350) 1 205233991 267096252 Rat 1598853 Memor3 Memory QTL 3 4.5 exploratory behavior trait (VT:0010471) total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443) 1 152919152 268496042 Rat 1600390 Niddm64 Non-insulin dependent diabetes mellitus QTL 64 0.003 blood glucose amount (VT:0000188) blood glucose level (CMO:0000046) 1 257624997 270518180 Rat 1300108 Rf8 Renal function QTL 8 3.75 renal blood flow trait (VT:2000006) absolute change in renal vascular resistance (CMO:0001900) 1 237995023 269633915 Rat 734767 Niddm57 Non-insulin dependent diabetes mellitus QTL 57 body mass (VT:0001259) body weight (CMO:0000012) 1 233480549 270108840 Rat 1354610 Bw34 Body weight QTL 34 4.1 body mass (VT:0001259) body weight (CMO:0000012) 1 160573753 266453731 Rat 631215 Stl8 Serum triglyceride level QTL 8 9.27 0.0001 blood triglyceride amount (VT:0002644) serum triglyceride level (CMO:0000360) 1 234540191 270518180 Rat 7387289 Uae45 Urinary albumin excretion QTL 45 2.86 0.0021 urine albumin amount (VT:0002871) urine albumin excretion rate (CMO:0000757) 1 233204160 270518180 Rat 631843 Bw116 Body weight QTL 116 4.1 0.016 abdominal adipose amount (VT:1000220) abdominal fat pad weight (CMO:0000088) 1 233480549 270108840 Rat 731175 Uae20 Urinary albumin excretion QTL 20 3.5 0.0018 urine albumin amount (VT:0002871) urine albumin excretion rate (CMO:0000757) 1 207163993 269633915 Rat 1598839 Rf56 Renal function QTL 56 renal blood flow trait (VT:2000006) ratio of change in renal blood flow to change in renal perfusion pressure (CMO:0001239) 1 255849111 270518180 Rat 1581544 Rf52 Renal function QTL 52 0.05 urine total protein amount (VT:0000032) urine protein excretion rate to body weight ratio (CMO:0001099) 1 241569529 269633915 Rat 1354661 Bw33 Body weight QTL 33 5.2 body mass (VT:0001259) body weight (CMO:0000012) 1 160573753 266453731 Rat 631536 Lnnr2 Liver neoplastic nodule remodeling QTL 2 2.9 0.0005 liver integrity trait (VT:0010547) liver remodeling tumorous lesion number to liver total tumorous lesion number ratio (CMO:0001705) 1 243953669 270518180 Rat 734769 Niddm58 Non-insulin dependent diabetes mellitus QTL 58 body mass (VT:0001259) body weight (CMO:0000012) 1 225108840 270108840 Rat 738032 Hcas5 Hepatocarcinoma susceptibility QTL 5 3.12 liver integrity trait (VT:0010547) liver tumorous lesion number (CMO:0001068) 1 185857683 270518180 Rat 2302040 Pia35 Pristane induced arthritis QTL 35 3.8 0.001 blood immunoglobulin amount (VT:0002460) serum immunoglobulin G1 level (CMO:0002115) 1 226175591 270518180 Rat 631669 Iddm9 Insulin dependent diabetes mellitus QTL 9 2.8 0.039 blood glucose amount (VT:0000188) plasma glucose level (CMO:0000042) 1 233349180 270518180 Rat 1598821 Rf55 Renal function QTL 55 6.3 renal blood flow trait (VT:2000006) ratio of change in renal blood flow to change in renal perfusion pressure (CMO:0001239) 1 228174566 270518180 Rat 724533 Rf51 Renal function QTL 51 5.3 0.0002 kidney plasma flow trait (VT:0005524) renal plasma flow (CMO:0001914) 1 228180370 266453608 Rat