P3r3urf (PIK3R3 upstream open reading frame) - Rat Genome Database

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Gene: P3r3urf (PIK3R3 upstream open reading frame) Rattus norvegicus
Analyze
Symbol: P3r3urf
Name: PIK3R3 upstream open reading frame
RGD ID: 6491750
Description: Orthologous to human P3R3URF (PIK3R3 upstream open reading frame).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC100911669; PIK3R3 upstream reading frame; uncharacterized LOC100911669; uncharacterized protein LOC100911669
RGD Orthologs
Human
Mouse
Bonobo
Dog
Squirrel
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85134,893,003 - 134,909,941 (+)NCBIGRCr8
mRatBN7.25129,656,654 - 129,673,140 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5129,656,833 - 129,672,848 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5132,273,082 - 132,274,052 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05134,027,670 - 134,028,640 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05134,050,106 - 134,051,076 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05135,029,480 - 135,046,282 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5135,029,955 - 135,030,801 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05138,813,697 - 138,829,793 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera5128,184,729 - 128,201,535 (+)NCBICelera
Cytogenetic Map5q35NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data
P3r3urf
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85134,893,003 - 134,909,941 (+)NCBIGRCr8
mRatBN7.25129,656,654 - 129,673,140 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5129,656,833 - 129,672,848 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5132,273,082 - 132,274,052 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05134,027,670 - 134,028,640 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05134,050,106 - 134,051,076 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05135,029,480 - 135,046,282 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5135,029,955 - 135,030,801 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05138,813,697 - 138,829,793 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera5128,184,729 - 128,201,535 (+)NCBICelera
Cytogenetic Map5q35NCBI
P3R3URF
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38146,175,486 - 46,176,488 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl146,175,486 - 46,176,488 (-)EnsemblGRCh38hg38GRCh38
GRCh37146,641,158 - 46,642,160 (-)NCBIGRCh37GRCh37hg19GRCh37
Cytogenetic Map1p34.1NCBI
T2T-CHM13v2.0146,052,681 - 46,053,683 (-)NCBIT2T-CHM13v2.0
P3r3urf
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394116,030,569 - 116,031,494 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4116,030,569 - 116,031,487 (+)EnsemblGRCm39 Ensembl
GRCm384116,173,372 - 116,174,297 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4116,173,372 - 116,174,290 (+)EnsemblGRCm38mm10GRCm38
MGSCv374115,845,977 - 115,846,902 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364115,845,883 - 115,846,902 (+)NCBIMGSCv36mm8
Celera4114,911,527 - 114,912,452 (+)NCBICelera
Cytogenetic Map4D1NCBI
cM Map453.1NCBI
P3R3URF
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21180,628,510 - 180,629,915 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11179,770,079 - 179,771,422 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0145,481,545 - 45,483,181 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1146,836,356 - 46,837,391 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl146,836,456 - 46,837,338 (-)Ensemblpanpan1.1panPan2
P3R3URF
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11514,197,285 - 14,198,026 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1514,197,316 - 14,198,024 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1514,319,201 - 14,319,937 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01514,349,659 - 14,350,395 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1514,349,685 - 14,350,393 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11514,150,714 - 14,151,450 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01514,219,199 - 14,219,935 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01514,288,825 - 14,289,561 (+)NCBIUU_Cfam_GSD_1.0
P3r3urf
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505861,391,964 - 61,392,906 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647427,216,835 - 27,217,647 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
P3R3URF
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12086,609,459 - 86,610,800 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366603330,375,884 - 30,377,456 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in P3r3urf
37 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:48
Count of miRNA genes:42
Interacting mature miRNAs:48
Transcripts:ENSRNOT00000074860
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
70212Niddm25Non-insulin dependent diabetes mellitus QTL 253.54blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)51131345958Rat
1576314Eutr1Estrogen induced uterine response QTL 1uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)52138965166875058Rat
2290448Scl54Serum cholesterol level QTL 542.93blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)531663789131345958Rat
1641912Alcrsp18Alcohol response QTL 18response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)535189153141643988Rat
1549845Scl44Serum cholesterol level QTL 446blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)540128307148607290Rat
1578766Tcas11Tongue tumor susceptibility QTL 114.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)546711509161317411Rat
1576312Emca8Estrogen-induced mammary cancer QTL 84.1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)550328551141643988Rat
70189Mcs5Mammary carcinoma susceptibility QTL 510.51mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)555805606132207589Rat
61426Scl2Serum cholesterol level QTL 27.30.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)559793399143070159Rat
61393Bp7Blood pressure QTL 74.50.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)560293434161481680Rat
1354598Srn6Serum renin concentration QTL 63.8blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)569540295151018848Rat
1302790Scl20Serum cholesterol level QTL 206.40.0001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)582394392166664054Rat
7411601Foco12Food consumption QTL 1219.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)587468046132468046Rat
7411564Bw135Body weight QTL 1350.001body mass (VT:0001259)body weight gain (CMO:0000420)587468046132468046Rat
7411582Foco3Food consumption QTL 37.50.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)587468046132468046Rat
6903316Bw113Body weight QTL 11320.0103body mass (VT:0001259)body weight (CMO:0000012)587765973132765973Rat
631527Tls1T-lymphoma susceptibility QTL 100.001thymus integrity trait (VT:0010555)post-insult time to onset of T-cell lymphoma (CMO:0001907)590450144135450144Rat
61452Ciaa5CIA Autoantibody QTL 53.5blood autoantibody amount (VT:0003725)calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)594858972143070159Rat
1331796Thshl2Thyroid stimulating hormone level QTL 22.3blood thyroid-stimulating hormone amount (VT:0005119)serum thyroid stimulating hormone level (CMO:0001248)597059760147465714Rat
2317753Glom24Glomerulus QTL 243.1kidney glomerulus integrity trait (VT:0010546)kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)597570330136479578Rat
1358187Emca1Estrogen-induced mammary cancer QTL 14.4mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)599216724148607142Rat
1578673Bmd13Bone mineral density QTL 134.9femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)5103689353148689353Rat
2317056Wbc3White blood cell count QTL 32.510.01leukocyte quantity (VT:0000217)white blood cell count (CMO:0000027)5105999803150999803Rat
7207488Bss110Bone structure and strength QTL 18.4femur strength trait (VT:0010010)femur stiffness (CMO:0001674)5106906205151906205Rat
7207491Bss112Bone structure and strength QTL 1127femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)5106906205151906205Rat
7207481Bss106Bone structure and strength QTL 1067.9femur strength trait (VT:0010010)femur ultimate force (CMO:0001675)5106906205151906205Rat
7207486Bss109Bone structure and strength QTL 109femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)5106906205151906205Rat
1549838Bss4Bone structure and strength QTL 49.2femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)5106906205151906205Rat
1298089Scl14Serum cholesterol level QTL 145.80.0004blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)5108845856153845856Rat
1598847Cm62Cardiac mass QTL 623.4heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)5108845856153845856Rat
8657050Bw146Body weight QTL 14619.840.001body mass (VT:0001259)body weight gain (CMO:0000420)5108938288153938288Rat
8694441Bw169Body weight QTL 16917.610.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)5111416838156416838Rat
8694198Abfw3Abdominal fat weight QTL 316.130.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)5111416838156416838Rat
8694389Bw160Body weight QTL 1606.170.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)5111416838156416838Rat
8552960Pigfal15Plasma insulin-like growth factor 1 level QTL 15blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)5111416838156416838Rat
1581510Cm54Cardiac mass QTL 543.40.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)5120740824143608494Rat
2293642Bss37Bone structure and strength QTL 374.640.0001femur strength trait (VT:0010010)femur ultimate force (CMO:0001675)5120740824151018848Rat
1641920Colcs1Colorectal carcinoma susceptibility QTL 12.990.0055intestine integrity trait (VT:0010554)benign colorectal tumor surface area measurement (CMO:0001799)5121846814166846814Rat
7394710Emca12Estrogen-induced mammary cancer QTL 12mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)5124160767133749643Rat
10053720Scort26Serum corticosterone level QTL 262.060.0147blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)5124965598166875058Rat
1300122Wbc1White blood cell count QTL 12.75leukocyte quantity (VT:0000217)total white blood cell count (CMO:0000365)5125392826139989768Rat
724525Bp147Blood pressure QTL 1474.30.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5126424772166875058Rat
1598819Bp292Blood pressure QTL 2924.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5127798274166875058Rat
1598861Cm64Cardiac mass QTL 642.9heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)5127798274166875058Rat
1581505Rf54Renal function QTL 54kidney physiology trait (VT:0002136)kidney 20-HETE level (CMO:0001854)5128033842133011550Rat
8552908Pigfal4Plasma insulin-like growth factor 1 level QTL 46.6blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)5128506074166875058Rat
8694169Bw148Body weight QTL 14850.001body mass (VT:0001259)body weight gain (CMO:0000420)5128506074166875058Rat
634349Bp139Blood pressure QTL 1390.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5128924607166875058Rat
1331803Rf32Renal function QTL 322.798kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)5129132428143070159Rat
70156Niddm30Non-insulin dependent diabetes mellitus QTL 303.98blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)5129132447151006154Rat


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High 3
Medium 4
Low 6 9 14 1 1 6
Below cutoff 1 14 10 7 3 7 2 2 5 4 6 4 2

Sequence


RefSeq Acc Id: ENSRNOT00000074860   ⟹   ENSRNOP00000067380
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5129,656,833 - 129,672,848 (+)Ensembl
Rnor_6.0 Ensembl5135,029,955 - 135,030,801 (+)Ensembl
RefSeq Acc Id: NM_001399355   ⟹   NP_001386284
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85134,893,571 - 134,894,540 (+)NCBI
mRatBN7.25129,656,856 - 129,657,825 (+)NCBI
RefSeq Acc Id: XM_008763983   ⟹   XP_008762205
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85134,893,003 - 134,909,941 (+)NCBI
mRatBN7.25129,656,654 - 129,673,140 (+)NCBI
Rnor_6.05135,029,480 - 135,046,282 (+)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001386284 (Get FASTA)   NCBI Sequence Viewer  
  XP_008762205 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000067380
  ENSRNOP00000067380.1
RefSeq Acc Id: XP_008762205   ⟸   XM_008763983
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSRNOP00000067380   ⟸   ENSRNOT00000074860
RefSeq Acc Id: NP_001386284   ⟸   NM_001399355
- UniProtKB: M0RCQ3 (UniProtKB/TrEMBL),   A6JZ69 (UniProtKB/TrEMBL)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-M0RCQ3-F1-model_v2 AlphaFold M0RCQ3 1-90 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13693942
Promoter ID:EPDNEW_R4457
Type:initiation region
Name:1700042G07Rik_1
Description:RIKEN cDNA 1700042G07 gene
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.05135,029,945 - 135,030,005EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:6491750 AgrOrtholog
BioCyc Gene G2FUF-40261 BioCyc
Ensembl Genes ENSRNOG00000049874 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000074860 ENTREZGENE
  ENSRNOT00000074860.2 UniProtKB/TrEMBL
NCBI Gene LOC100911669 ENTREZGENE
PhenoGen P3r3urf PhenoGen
RatGTEx ENSRNOG00000049874 RatGTEx
UniProt A6JZ69 ENTREZGENE, UniProtKB/TrEMBL
  M0RCQ3 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-18 P3r3urf  PIK3R3 upstream open reading frame  P3r3urf  PIK3R3 upstream reading frame  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2018-12-10 P3r3urf  PIK3R3 upstream reading frame  LOC100911669  uncharacterized LOC100911669  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2012-07-05 LOC100911669  uncharacterized LOC100911669      Symbol and Name status set to provisional 70820 PROVISIONAL