Mrgprx1 (MAS related GPR family member X1) - Rat Genome Database

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Gene: Mrgprx1 (MAS related GPR family member X1) Rattus norvegicus
Analyze
Symbol: Mrgprx1
Name: MAS related GPR family member X1
RGD ID: 632284
Description: Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to act upstream of or within chemosensory behavior and hematopoietic progenitor cell differentiation. Predicted to be located in membrane. Predicted to be active in plasma membrane. Orthologous to several human genes including MRGPRX4 (MAS related GPR family member X4); INTERACTS WITH bisphenol A; 1,2-dichloroethane (ortholog); benzo[a]pyrene (ortholog).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: G protein-coupled receptor SNSR; MAS related GPR family member X4; Mas-related G protein-coupled receptor g2; mas-related G-protein coupled receptor member X1; MAS-related G-protein coupled receptor, member C; MAS-related gene C; MAS-related GPR, member C11; MAS-related GPR, member X1; MAS-related GPR, member X4; Mgrg2; MrgC; Mrgprc; Mrgprc11; Mrgprx4; sensory neuron-specific G protein-coupled receptor 1; sensory neuron-specific G-protein coupled receptor 1; Sensory neuron-specific receptor; Snsr; Snsr1
RGD Orthologs
Human
Mouse
Bonobo
Dog
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81106,942,343 - 106,943,314 (-)NCBIGRCr8
mRatBN7.2197,806,099 - 97,807,070 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl197,806,099 - 97,807,112 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1103,184,574 - 103,185,587 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01111,656,540 - 111,657,553 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01104,954,373 - 104,955,386 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01103,378,242 - 103,388,240 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01104,442,354 - 104,451,268 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4197,919,939 - 97,920,952 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1197,997,918 - 97,999,233 (-)NCBI
Celera192,046,235 - 92,047,248 (-)NCBICelera
Cytogenetic Map1q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Proenkephalin A gene products activate a new family of sensory neuron--specific GPCRs. Lembo PM, etal., Nat Neurosci 2002 Mar;5(3):201-9.
3. GOA pipeline RGD automated data pipeline
4. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Atypical expansion in mice of the sensory neuron-specific Mrg G protein-coupled receptor family. Zylka MJ, etal., Proc Natl Acad Sci U S A 2003 Aug 19;100(17):10043-8. Epub 2003 Aug 8.
Additional References at PubMed
PMID:18065157   PMID:18250432   PMID:19307060   PMID:23000623   PMID:23074220   PMID:24029230   PMID:24374082   PMID:24583173   PMID:26022362   PMID:26157044   PMID:30487293  


Genomics

Comparative Map Data
Mrgprx1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81106,942,343 - 106,943,314 (-)NCBIGRCr8
mRatBN7.2197,806,099 - 97,807,070 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl197,806,099 - 97,807,112 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1103,184,574 - 103,185,587 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01111,656,540 - 111,657,553 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01104,954,373 - 104,955,386 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01103,378,242 - 103,388,240 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01104,442,354 - 104,451,268 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4197,919,939 - 97,920,952 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1197,997,918 - 97,999,233 (-)NCBI
Celera192,046,235 - 92,047,248 (-)NCBICelera
Cytogenetic Map1q22NCBI
MRGPRX4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381118,172,837 - 18,174,280 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1118,172,837 - 18,174,280 (+)EnsemblGRCh38hg38GRCh38
GRCh371118,194,384 - 18,195,827 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361118,150,960 - 18,152,401 (+)NCBINCBI36Build 36hg18NCBI36
Celera1118,326,688 - 18,328,131 (+)NCBICelera
Cytogenetic Map11p15.1NCBI
HuRef1117,877,287 - 17,878,730 (+)NCBIHuRef
CHM1_11118,193,904 - 18,195,347 (+)NCBICHM1_1
T2T-CHM13v2.01118,268,336 - 18,269,779 (+)NCBIT2T-CHM13v2.0
Mrgprx1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39747,670,719 - 47,677,345 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl747,670,719 - 47,677,345 (-)EnsemblGRCm39 Ensembl
GRCm38748,020,971 - 48,027,597 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl748,020,971 - 48,027,597 (-)EnsemblGRCm38mm10GRCm38
MGSCv37755,276,341 - 55,282,967 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36747,888,993 - 47,895,623 (-)NCBIMGSCv36mm8
MGSCv36737,623,113 - 37,641,258 (-)NCBIMGSCv36mm8
Cytogenetic Map7B4NCBI
cM Map731.09NCBI
MRGPRX4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2920,504,297 - 20,505,746 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11120,464,682 - 20,466,131 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01118,225,283 - 18,226,720 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11117,905,593 - 17,907,030 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1117,906,013 - 17,906,981 (+)Ensemblpanpan1.1panPan2
MGRH
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11847,212,903 - 47,215,195 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1845,820,986 - 45,823,278 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01847,893,505 - 47,895,798 (+)NCBIROS_Cfam_1.0
UMICH_Zoey_3.11847,334,379 - 47,336,671 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01846,920,538 - 46,922,830 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01847,667,032 - 47,669,325 (+)NCBIUU_Cfam_GSD_1.0

Variants

.
Variants in Mrgprx1
3 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:12
Count of miRNA genes:12
Interacting mature miRNAs:12
Transcripts:ENSRNOT00000019061
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2313059Bss55Bone structure and strength QTL 553.20.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)143284731118944897Rat
70209Niddm23Non-insulin dependent diabetes mellitus QTL 232.82blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)194494440198324465Rat
631688Hcas2Hepatocarcinoma susceptibility QTL 230.0001liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)15925874115540829Rat
1582234Gluco18Glucose level QTL 183.40.0003blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)178479925123479925Rat
1358359Sradr1Stress Responsive Adrenal Weight QTL 14.74adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)130882023123479925Rat
634314Niddm44Non-insulin dependent diabetes mellitus QTL 44blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)149393289199050459Rat
1578780Cm52Cardiac mass QTL 523.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)181591954219808434Rat
1331793Bp200Blood pressure QTL 2003.71601arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)194494440172949803Rat
1578654Bss10Bone structure and strength QTL 104femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)149393172159356837Rat
2300324Fetw1Fetal weight QTL 112.10.005fetal growth trait (VT:0004201)fetal body weight (CMO:0002080)185424647100358001Rat
1300121Hrtrt1Heart rate QTL 13.7heart pumping trait (VT:2000009)heart rate (CMO:0000002)165789093115540829Rat
1331800Scl25Serum cholesterol level QTL 253.013blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)194494440117601394Rat
7421628Bp361Blood pressure QTL 3610.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)166023617118608521Rat
631495Bp96Blood pressure QTL 964.52arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)122340647102268831Rat
70225Bp58Blood pressure QTL 583.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)132356093162846471Rat
2298545Neuinf8Neuroinflammation QTL 84.6nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)157336763151090257Rat
2313072Bss53Bone structure and strength QTL 534.30.0001tibia length (VT:0004357)tibia length (CMO:0000450)143284731118944897Rat
10059597Bp377Blood pressure QTL 3773.420.025arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)132737458199368955Rat
2313078Bss54Bone structure and strength QTL 543.50.0001tibia area (VT:1000281)tibia midshaft cross-sectional area (CMO:0001717)143284731118944897Rat
1302788Scl19Serum cholesterol QTL 194.60.001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)190532338123479925Rat
1549903Bp267Blood pressure QTL 267arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)177876254106047988Rat
2313083Bmd74Bone mineral density QTL 7440.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)182174743118944897Rat
2313402Anxrr24Anxiety related response QTL 24aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)148963584144267916Rat
4889494Scort2Serum corticosterone level QTL 24.2blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)180592172125592172Rat
724567Tcas6Tongue tumor susceptibility QTL 66.85tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)192948896144267916Rat
61342Bp27Blood pressure QTL 273.40.0006arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)15673266898773277Rat
61344Bp29Blood pressure QTL 297.5arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)178350581123350581Rat
724521Uae1Urinary albumin excretion QTL 13.80.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)190508614173018436Rat
1358902Bw47Body weight QTL 471.67body mass (VT:0001259)body weight (CMO:0000012)190508614180359386Rat
1358192Ept13Estrogen-induced pituitary tumorigenesis QTL 133.4pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)177494165122494165Rat
2313094Bss58Bone structure and strength QTL 583.70.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)143284731118944897Rat
2300164Bmd44Bone mineral density QTL 445.40.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)156949932101949932Rat
2313099Bss56Bone structure and strength QTL 562.40.0001tibia size trait (VT:0100001)tibia midshaft endosteal cross-sectional area (CMO:0001716)143284731118944897Rat
2313098Bmd70Bone mineral density QTL 703.60.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)143284731118944897Rat
1300153Bp171Blood pressure QTL 1713.37arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)190664883143200202Rat
731168Bp154Blood pressure QTL 1543.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)194642644214537671Rat
738022Anxrr13Anxiety related response QTL 134.60.00039locomotor behavior trait (VT:0001392)number of 20 x 20 cm floor squares crossed into, out of or within a discrete space in an experimental apparatus (CMO:0001514)183547917128547917Rat
10054135Gmadr2Adrenal mass QTL 21.970.0129adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)177857876122857876Rat
7411712Strs4Sensitivity to stroke QTL 48.7cerebrum integrity trait (VT:0010549)percentage of study population developing cerebrovascular lesions during a period of time (CMO:0000932)178430536123430536Rat
1331749Hrtrt11Heart rate QTL 112.973heart pumping trait (VT:2000009)heart rate (CMO:0000002)194494440198211706Rat
1331751Bp199Blood pressure QTL 1993.60022arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)194494440181830018Rat
2293142Bp314Blood pressure QTL 314arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)192184926137184926Rat
2313051Bss57Bone structure and strength QTL 573.70.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)143284731118944897Rat
724529Cm16Cardiac mass QTL 162.7heart mass (VT:0007028)calculated heart weight (CMO:0000073)187580395150700247Rat


Expression

RNA-SEQ Expression

circulatory system
ectoderm
endocrine system
endoderm
mesenchyme
mesoderm
nervous system
respiratory system
1 7 1 2 2 2 6 2

Sequence


Ensembl Acc Id: ENSRNOT00000019061   ⟹   ENSRNOP00000019061
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl197,806,099 - 97,807,112 (-)Ensembl
Rnor_6.0 Ensembl1103,379,325 - 103,380,338 (-)Ensembl
RefSeq Acc Id: NM_172158   ⟹   NP_750845
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81106,942,343 - 106,943,314 (-)NCBI
mRatBN7.2197,806,099 - 97,807,070 (-)NCBI
Rnor_6.01103,379,325 - 103,380,338 (-)NCBI
Rnor_5.01104,442,354 - 104,451,268 (-)NCBI
RGSC_v3.4197,919,939 - 97,920,952 (-)RGD
Celera192,046,235 - 92,047,248 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_750845 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAL86877 (Get FASTA)   NCBI Sequence Viewer  
  AAQ08317 (Get FASTA)   NCBI Sequence Viewer  
  CAI95954 (Get FASTA)   NCBI Sequence Viewer  
  CDG86241 (Get FASTA)   NCBI Sequence Viewer  
  EDM07235 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000019061.1
  ENSRNOP00065010928
GenBank Protein Q8R4G1 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_750845   ⟸   NM_172158
- UniProtKB: Q8R4G1 (UniProtKB/Swiss-Prot),   Q7TN42 (UniProtKB/Swiss-Prot),   A0A096MIT0 (UniProtKB/TrEMBL),   W8W3G5 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000019061   ⟸   ENSRNOT00000019061
Protein Domains
G-protein coupled receptors family 1 profile

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q8R4G1-F1-model_v2 AlphaFold Q8R4G1 1-323 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:632284 AgrOrtholog
BioCyc Gene G2FUF-59589 BioCyc
Ensembl Genes ENSRNOG00000014242 Ensembl, UniProtKB/TrEMBL
  ENSRNOG00065009144 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000019061.3 UniProtKB/TrEMBL
  ENSRNOT00065014599 UniProtKB/Swiss-Prot
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro GPCR_Rhodpsn UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPCR_Rhodpsn_7TM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MRGPCRFAMILY UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:282547 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 282547 ENTREZGENE
PANTHER MAS-RELATED G-PROTEIN COUPLED RECEPTOR MEMBER X1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR11334 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam 7tm_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Mrgprx1 PhenoGen
PRINTS GPCRRHODOPSN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MRGPCRFAMILY UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000014242 RatGTEx
  ENSRNOG00065009144 RatGTEx
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A096MIT0 ENTREZGENE, UniProtKB/TrEMBL
  MRGX1_RAT UniProtKB/Swiss-Prot
  Q7TN42 ENTREZGENE
  Q8R4G1 ENTREZGENE
  W8W3G5 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary Q7TN42 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-07-07 Mrgprx1  MAS related GPR family member X1  Mrgprc  MAS-related G-protein coupled receptor, member C  Data merged from RGD:738054 737654 PROVISIONAL
2022-07-07 Mrgprx1  MAS related GPR family member X1  Mrgprx4  MAS related GPR family member X4  Name and Symbol changed 629549 APPROVED
2015-12-02 Mrgprx4  MAS related GPR family member X4  Mrgprx4  MAS-related GPR, member X4  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2012-10-05 Mrgprx4  MAS-related GPR, member X4  Mrgprx1  MAS-related GPR, member X1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2007-03-16 Mrgprx1  MAS-related GPR, member X1  Mrgprc11  MAS-related GPR, member C11  Symbol and Name updated to reflect Human and Mouse nomenclature 1299863 APPROVED
2005-07-08 Mrgprc11  MAS-related GPR, member C11  Snsr1  sensory neuron-specific G protein-coupled receptor 1  Symbol and Name updated 1299863 APPROVED
2004-03-30 Mrgprc  MAS-related G-protein coupled receptor, member C      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_expression expressed in small sensory neurons 625545
gene_expression uniquely localized to dorsal root ganglia and trigeminal ganglia 625545
gene_expression expressed in nociceptive sensory neurons, dorsal root ganglia, and in trigeminal ganglia 737883
gene_homology highest homology with mouse receptor family of MRGC 625545
gene_mapping Mrgpra, Mrgprb and Mrgprc are located within a 760-kb cluster on chr 1 737883
gene_other rat has single Mrgprc gene, unlike mouse which has 14 737883
gene_process may be involved in sensory neuron regulation and nociception modulation 625545
gene_product member of the Mas-related gene (Mrg) family, based on ligand which activates the receptor 737883