Nrep (neuronal regeneration related protein)

	Submit Data \| Help \| Video Tutorials \| News \| Publications \| Download \| REST API \| Citing RGD \| Contact
	Search RGD Grant Resources Citing RGD About Us Contact Us Genes Projects (beta) QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) (beta) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer) Overgo Probe Designer Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease COVID-19 Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease Find Models new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes GERRC (Gene Editing Rat Resource Center) Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive Pathways Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Poster Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
	Advanced Search (OLGA)

Gene: Nrep (neuronal regeneration related protein) Rattus norvegicus

Analyze

Symbol:

Nrep

Name:

neuronal regeneration related protein

RGD ID:

631411

Description:

Involved in axon regeneration and regulation of neuron differentiation. Predicted to be located in cytoplasm. Orthologous to human NREP (neuronal regeneration related protein); INTERACTS WITH (+)-schisandrin B; 1,3,5-trinitro-1,3,5-triazinane; 1-naphthyl isothiocyanate.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

neuronal protein 3.1; neuronal regeneration-related protein; P311

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	18	25,017,069 - 25,046,593 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	18	25,017,083 - 25,046,591 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	18	25,145,975 - 25,172,066 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	18	25,908,623 - 25,934,991 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	18	25,241,653 - 25,267,744 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	18	26,183,753 - 26,212,796 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	18	26,185,259 - 26,211,445 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	18	25,898,561 - 25,927,610 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	18	25,842,127 - 25,868,219 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	18	25,868,772 - 25,894,865 (-)	NCBI
Celera	18	24,763,452 - 24,789,542 (-)	NCBI		Celera
Cytogenetic Map	18	p12	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Chemical and Drug Induced Liver Injury (ISO)

COVID-19 (ISO)

Experimental Liver Cirrhosis (ISO)

familial adenomatous polyposis 1 (ISO)

fatty liver disease (ISO)

genetic disease (ISO)

Hereditary Neoplastic Syndromes (ISO)

Neurodevelopmental Disorders (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-schisandrin B (EXP)

(-)-demecolcine (ISO)

(-)-epigallocatechin 3-gallate (ISO)

(1->4)-beta-D-glucan (ISO)

(R)-pantothenic acid (ISO)

1,2-dichloroethane (ISO)

1,3,5-trinitro-1,3,5-triazinane (EXP)

1-chloro-2,4-dinitrobenzene (ISO)

1-naphthyl isothiocyanate (EXP)

17beta-estradiol (EXP,ISO)

2,2',4,4'-Tetrabromodiphenyl ether (ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4-diaminotoluene (ISO)

3,3',4,4'-tetrachlorobiphenyl (ISO)

3,3',5,5'-tetrabromobisphenol A (ISO)

3-chloropropane-1,2-diol (EXP)

3-methylcholanthrene (ISO)

4,4'-diaminodiphenylmethane (EXP)

4-(ethoxymethylene)-2-phenyloxazol-5-one (ISO)

acetamide (EXP)

acrylamide (EXP,ISO)

adefovir pivoxil (ISO)

all-trans-retinoic acid (ISO)

amiodarone (EXP)

amitriptyline (EXP)

ammonium chloride (EXP)

amphibole asbestos (ISO)

antirheumatic drug (ISO)

aristolochic acid A (ISO)

arsane (ISO)

arsenic atom (ISO)

arsenous acid (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

bromobenzene (EXP)

buspirone (EXP)

butanal (ISO)

cadmium atom (ISO)

cadmium dichloride (EXP,ISO)

carbon nanotube (ISO)

celastrol (ISO)

chloroacetaldehyde (ISO)

chlorpyrifos (ISO)

chromium(6+) (ISO)

cidofovir anhydrous (ISO)

ciglitazone (ISO)

clodronic acid (ISO)

clomipramine (EXP)

cobalt dichloride (EXP,ISO)

copper atom (EXP,ISO)

copper(0) (EXP,ISO)

copper(II) sulfate (ISO)

coumarin (EXP)

crocidolite asbestos (ISO)

cyclosporin A (ISO)

dexamethasone (ISO)

diallyl disulfide (ISO)

diarsenic trioxide (ISO)

dibenz[a,h]anthracene (ISO)

dichloroacetic acid (ISO)

diclofenac (ISO)

Didecyldimethylammonium (ISO)

diethyl maleate (EXP)

dioxygen (ISO)

diquat (ISO)

diuron (EXP)

doxorubicin (ISO)

endosulfan (EXP)

entinostat (ISO)

epoxiconazole (ISO)

ethanol (ISO)

ethyl methanesulfonate (ISO)

fenofibrate (ISO)

fipronil (EXP)

flutamide (EXP)

folic acid (ISO)

formaldehyde (ISO)

fulvestrant (ISO)

gedunin (ISO)

genistein (ISO)

gentamycin (EXP)

glafenine (EXP)

glycidol (EXP)

hydralazine (ISO)

ifosfamide (ISO)

imipramine (EXP)

indole-3-methanol (EXP)

inulin (ISO)

ketamine (EXP)

ketoconazole (EXP)

L-ascorbic acid (ISO)

lead diacetate (EXP)

lead(0) (ISO)

leflunomide (EXP)

Licochalcone B (ISO)

lipopolysaccharide (ISO)

manganese(II) chloride (EXP)

methoxychlor (EXP)

methyl methanesulfonate (ISO)

methylmercury chloride (ISO)

mono(2-ethylhexyl) phthalate (ISO)

Monobutylphthalate (ISO)

N-nitrosodiethylamine (EXP,ISO)

N-nitrosodimethylamine (EXP)

nefazodone (EXP)

nevirapine (EXP)

nickel atom (ISO)

nickel sulfate (ISO)

nimesulide (EXP)

orphenadrine (EXP)

oxaliplatin (EXP)

oxycodone (EXP)

ozone (ISO)

p-toluidine (EXP)

paracetamol (EXP,ISO)

paraquat (EXP)

perfluorooctane-1-sulfonic acid (ISO)

phenobarbital (ISO)

phenylephrine (EXP)

piperonyl butoxide (EXP)

pirinixic acid (ISO)

potassium chromate (ISO)

pregnenolone 16alpha-carbonitrile (ISO)

quercetin (ISO)

raloxifene (ISO)

rotenone (EXP)

S-(1,2-dichlorovinyl)-L-cysteine (ISO)

serpentine asbestos (ISO)

silicon dioxide (ISO)

silver atom (ISO)

silver(0) (ISO)

sodium arsenate (ISO)

sodium dichromate (EXP)

sotorasib (ISO)

sulforaphane (ISO)

sunitinib (ISO)

tamoxifen (ISO)

temozolomide (ISO)

testosterone (ISO)

tetrachloromethane (EXP,ISO)

thapsigargin (ISO)

theophylline (ISO)

thioacetamide (EXP)

titanium dioxide (ISO)

topotecan (EXP)

trametinib (ISO)

tributylstannane (ISO)

trichloroethene (EXP)

triphenyl phosphate (EXP)

triptonide (ISO)

tunicamycin (ISO)

urethane (ISO)

valdecoxib (EXP)

valproic acid (ISO)

vincristine (ISO)

zoledronic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

axon regeneration (IBA,IEP)

regulation of neuron differentiation (IBA,IMP)

regulation of transforming growth factor beta receptor signaling pathway (IBA,ISO)

Cellular Component

cytoplasm (IEA)

Molecular Function

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	P311 accelerates nerve regeneration of the axotomized facial nerve.	Fujitani M, etal., J Neurochem 2004 Nov;91(3):737-44.
2.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3.	GOA pipeline	RGD automated data pipeline
4.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
6.	Information Derived from GenBank Report	RGD, Sept. 2003

Additional References at PubMed

PMID:14985127	PMID:26335191	PMID:26559022	PMID:29436600	PMID:35779227

Genomics

Comparative Map Data

Nrep
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	18	25,017,069 - 25,046,593 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	18	25,017,083 - 25,046,591 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	18	25,145,975 - 25,172,066 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	18	25,908,623 - 25,934,991 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	18	25,241,653 - 25,267,744 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	18	26,183,753 - 26,212,796 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	18	26,185,259 - 26,211,445 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	18	25,898,561 - 25,927,610 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	18	25,842,127 - 25,868,219 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	18	25,868,772 - 25,894,865 (-)	NCBI
Celera	18	24,763,452 - 24,789,542 (-)	NCBI		Celera
Cytogenetic Map	18	p12	NCBI

NREP
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	5	111,728,802 - 111,976,932 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	5	111,662,621 - 111,997,464 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	5	111,064,499 - 111,312,629 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	5	111,092,892 - 111,120,854 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	5	111,092,891 - 111,120,854	NCBI
Celera	5	107,010,594 - 107,258,308 (-)	NCBI		Celera
Cytogenetic Map	5	q22.1	NCBI
HuRef	5	106,243,630 - 106,491,590 (-)	NCBI		HuRef
CHM1_1	5	110,498,248 - 110,745,872 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	5	112,239,135 - 112,487,266 (-)	NCBI		T2T-CHM13v2.0

Nrep
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	18	33,570,072 - 33,597,444 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	18	33,570,072 - 33,597,082 (-)	Ensembl		GRCm39 Ensembl
GRCm38	18	33,437,019 - 33,464,365 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	18	33,437,019 - 33,464,029 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	18	33,596,673 - 33,623,683 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	18	33,561,830 - 33,588,243 (-)	NCBI		MGSCv36	mm8
Celera	18	33,884,768 - 33,926,480 (-)	NCBI		Celera
Cytogenetic Map	18	B1	NCBI
cM Map	18	18.18	NCBI

Nrep
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955418	3,436,731 - 3,464,667 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955418	3,435,784 - 3,464,667 (+)	NCBI	ChiLan1.0	ChiLan1.0

NREP
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1	5	105,139,515 - 105,387,522 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	5	107,089,968 - 107,118,919 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	5	112,891,542 - 113,139,436 (-)	NCBI	panpan1.1	PanPan1.1	panPan2

NREP
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	3	997,142 - 1,025,215 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	3	997,234 - 1,024,087 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	3	2,288,883 - 2,426,407 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	3	735,742 - 872,096 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	3	843,872 - 872,093 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	3	723,818 - 861,319 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	3	720,454 - 857,987 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	3	884,007 - 1,021,530 (+)	NCBI		UU_Cfam_GSD_1.0

Nrep
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024407213	155,505,760 - 155,533,814 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936531	6,077,716 - 6,104,479 (-)	Ensembl	SpeTri2.0
SpeTri2.0	NW_004936531	6,077,691 - 6,105,517 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

NREP
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	2	117,838,660 - 117,867,801 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	2	117,505,851 - 117,867,805 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	2	122,373,456 - 122,393,187 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

NREP
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	23	15,065,565 - 15,314,999 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	23	15,064,445 - 15,093,992 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666034	63,154,650 - 63,403,845 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Nrep
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624743	29,529,356 - 29,557,414 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624743	29,529,356 - 29,557,620 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Nrep
191 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	33
Count of miRNA genes:	27
Interacting mature miRNAs:	32
Transcripts:	ENSRNOT00000027739
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
8552968	Pigfal19	Plasma insulin-like growth factor 1 level QTL 19	11.4		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	18	1	25758124	Rat
9590248	Scort10	Serum corticosterone level QTL 10	19.71	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	18	1	25758124	Rat
2312598	Bp340	Blood pressure QTL 340		0.05	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	18	1	30558703	Rat
2300180	Bmd67	Bone mineral density QTL 67	4.8	0.0001	femur mineral mass (VT:0010011)	bone mineral density (CMO:0001226)	18	1	34291613	Rat
2293661	Bss50	Bone structure and strength QTL 50	4.64	0.0003	lumbar vertebra size trait (VT:0010518)	lumbar vertebra trabecular cross-sectional area (CMO:0001692)	18	1	34291613	Rat
61388	Bp2	Blood pressure QTL 2	3.23		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	18	1	35374722	Rat
9589153	Insul31	Insulin level QTL 31	7.15	0.05	blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	18	1	42547119	Rat
2299160	Iddm35	Insulin dependent diabetes mellitus QTL 35	2.79		blood glucose amount (VT:0000188)	age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)	18	4207941	60377792	Rat
2312568	Glom21	Glomerulus QTL 21	2	0.005	kidney glomerulus morphology trait (VT:0005325)	index of glomerular damage (CMO:0001135)	18	5185858	40503530	Rat
2293708	Bss46	Bone structure and strength QTL 46	8.8	0.0001	lumbar vertebra morphology trait (VT:0010494)	lumbar vertebra cortical cross-sectional area (CMO:0001690)	18	11791518	63636873	Rat
1578661	Bss20	Bone structure and strength QTL 20	3.7		femur morphology trait (VT:0000559)	femoral neck cross-sectional area (CMO:0001697)	18	11791518	83218561	Rat
1578667	Bss21	Bone structure and strength QTL 21	3.5		femur morphology trait (VT:0000559)	femoral neck cortical cross-sectional area (CMO:0001702)	18	11791518	83218561	Rat
61382	Bp46	Blood pressure QTL 46	18.8		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	18	11941791	31393320	Rat
631264	Scl22	Serum cholesterol level QTL 22	6.2		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	18	11941791	31393320	Rat
12904690	Cm129	Cardiac mass QTL 129		0.001	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	18	11944273	26548295	Rat
12904689	Cm128	Cardiac mass QTL 128		0.001	heart mass (VT:0007028)	heart wet weight to body weight ratio (CMO:0002408)	18	11944273	26548295	Rat
12904693	Am20	Aortic mass QTL 20		0.001	aorta mass (VT:0002845)	aorta weight to aorta length to body weight ratio (CMO:0002722)	18	11944273	26548295	Rat
12904695	Kidm73	Kidney mass QTL 73		0.001	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	18	11944273	26548295	Rat
12904691	Cm130	Cardiac mass QTL 130		0.001	heart right ventricle mass (VT:0007033)	heart right ventricle weight to body weight ratio (CMO:0000914)	18	11944273	26548295	Rat
12904680	Bw189	Body weight QTL 189		0.019	body mass (VT:0001259)	body weight (CMO:0000012)	18	11944273	26548295	Rat
2301410	Bp317	Blood pressure QTL 317		0.004	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	11944273	26548295	Rat
1331766	Bp236	Blood pressure QTL 236	3.022		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	11944299	31359530	Rat
61375	Bp41	Blood pressure QTL 41	2.4		blood pressure trait (VT:0000183)	systolic blood pressure (CMO:0000004)	18	11944299	41122201	Rat
1331753	Bp231	Blood pressure QTL 231	3.643		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	18	11944299	52293055	Rat
1358358	Sradr6	Stress Responsive Adrenal Weight QTL 6	2.49		adrenal gland mass (VT:0010420)	both adrenal glands wet weight (CMO:0000164)	18	11944299	59330563	Rat
6903359	Bp355	Blood pressure QTL 355	3.6		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	18	11944544	59796478	Rat
2313082	Bss85	Bone structure and strength QTL 85	0.8	0.0001	long bone metaphysis morphology trait (VT:0000133)	tibia midshaft total cross-sectional area (CMO:0001715)	18	14951337	59951337	Rat
1358193	Emca2	Estrogen-induced mammary cancer QTL 2	1.6		mammary gland integrity trait (VT:0010552)	post-insult time to mammary tumor formation (CMO:0000345)	18	18007599	63571040	Rat
1331735	Rf44	Renal function QTL 44	2.981		urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	18	18234564	31359530	Rat
1331775	Bp235	Blood pressure QTL 235	3.201		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	18234564	31359530	Rat
1600373	Mamtr6	Mammary tumor resistance QTL 6			mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	18	19278901	83218561	Rat
1331741	Bp232	Blood pressure QTL 232	3.59112		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	18	21372893	83213037	Rat
1641923	Colcr8	Colorectal carcinoma resistance QTL 8	3.1	0.0014	intestine integrity trait (VT:0010554)	poorly differentiated malignant colorectal tumor number (CMO:0002076)	18	22066242	52293055	Rat
1331733	Bp233	Blood pressure QTL 233	3.97196		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	18	24796977	79788953	Rat

Markers in Region

PMC151607P1

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	18	25,017,665 - 25,018,002 (+)	MAPPER	mRatBN7.2
Rnor_6.0	18	26,184,350 - 26,184,686	NCBI	Rnor6.0
Rnor_5.0	18	25,899,158 - 25,899,494	UniSTS	Rnor5.0
RGSC_v3.4	18	25,841,218 - 25,841,554	UniSTS	RGSC3.4
Celera	18	24,762,543 - 24,762,879	UniSTS
Cytogenetic Map	18	p12	UniSTS

G54138

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	18	25,017,385 - 25,017,531 (+)	MAPPER	mRatBN7.2
Rnor_6.0	18	26,184,070 - 26,184,215	NCBI	Rnor6.0
Rnor_5.0	18	25,898,878 - 25,899,023	UniSTS	Rnor5.0
RGSC_v3.4	18	25,840,938 - 25,841,083	UniSTS	RGSC3.4
Celera	18	24,762,263 - 24,762,408	UniSTS
Cytogenetic Map	18	p12	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High									43	4
Medium	3	40	43	38	9	38	8	11	31	31	39	11	8
Low		3	14	3	10	3					2
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001419560	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001419561	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AB072344	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY724475	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473974	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ213250	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ214488	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000299	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSRNOT00000027739 ⟹ ENSRNOP00000027739

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	18	26,185,259 - 26,211,445 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000119499 ⟹ ENSRNOP00000086813

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	18	25,017,083 - 25,046,591 (-)	Ensembl

RefSeq Acc Id:

NM_001419560 ⟹ NP_001406489

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	18	25,017,069 - 25,046,593 (-)	NCBI

RefSeq Acc Id:

NM_001419561 ⟹ NP_001406490

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	18	25,017,069 - 25,045,975 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_001406489	(Get FASTA)	NCBI Sequence Viewer
	NP_001406490	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	BAC65245	(Get FASTA)	NCBI Sequence Viewer
	EDL76200	(Get FASTA)	NCBI Sequence Viewer
	EDL76201	(Get FASTA)	NCBI Sequence Viewer
	EDL76202	(Get FASTA)	NCBI Sequence Viewer
	EDL76203	(Get FASTA)	NCBI Sequence Viewer
	EDL76204	(Get FASTA)	NCBI Sequence Viewer
	EDL76205	(Get FASTA)	NCBI Sequence Viewer
	Q80Z34	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

ENSRNOP00000027739 ⟸ ENSRNOT00000027739

RefSeq Acc Id:

ENSRNOP00000086813 ⟸ ENSRNOT00000119499

RefSeq Acc Id:	NP_001406489 ⟸ NM_001419560
- UniProtKB:	Q80Z34 (UniProtKB/Swiss-Prot), A6J2S2 (UniProtKB/TrEMBL)

RefSeq Acc Id:	NP_001406490 ⟸ NM_001419561
- UniProtKB:	Q80Z34 (UniProtKB/Swiss-Prot), A6J2S2 (UniProtKB/TrEMBL)

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q80Z34-F1-model_v2	AlphaFold	Q80Z34	1-68	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:631411	AgrOrtholog
BioCyc Gene	G2FUF-7997	BioCyc
Ensembl Genes	ENSRNOG00000020467	Ensembl
	ENSRNOG00000068914	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein	ENSRNOP00000086813	ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000119499	ENTREZGENE, UniProtKB/Swiss-Prot
InterPro	Neuronal_3.1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	rno:338475	UniProtKB/Swiss-Prot
NCBI Gene	338475	ENTREZGENE
PANTHER	NEURONAL REGENERATION-RELATED PROTEIN	UniProtKB/Swiss-Prot
	NEURONAL REGENERATION-RELATED PROTEIN	UniProtKB/TrEMBL
	NEURONAL REGENERATION-RELATED PROTEIN	UniProtKB/TrEMBL
	PTHR17102	UniProtKB/Swiss-Prot
Pfam	Alveol-reg_P311	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Nrep	PhenoGen
UniProt	A6J2R9_RAT	UniProtKB/TrEMBL
	A6J2S2	ENTREZGENE, UniProtKB/TrEMBL
	NREP_RAT	UniProtKB/Swiss-Prot, ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2005-07-08	Nrep	neuronal regeneration related protein			Symbol and Name status set to approved	1299863	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Send us a Message

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD