Nup58 (nucleoporin 58) - Rat Genome Database

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Gene: Nup58 (nucleoporin 58) Rattus norvegicus
Analyze
Symbol: Nup58
Name: nucleoporin 58
RGD ID: 631334
Description: Enables identical protein binding activity and nuclear localization sequence binding activity. A structural constituent of nuclear pore. Involved in nucleocytoplasmic transport and regulation of protein import into nucleus. Located in nuclear envelope. Part of nuclear pore. Orthologous to human NUP58 (nucleoporin 58); PARTICIPATES IN mRNA nuclear export pathway; RNA transport pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 2,4-dinitrotoluene; 3-chloropropane-1,2-diol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: 58 kDa nucleoporin; nucleoporin like 1; nucleoporin p45; nucleoporin p58; nucleoporin p58/p45; nucleoporin-like 1; nucleoporin-like protein 1; Nup45; Nupl1; p58/p45
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Allele / Splice: Nup58_v2   Nup58_v3   Nup58_v1   Nup58_v4  
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81538,534,340 - 38,583,959 (-)NCBIGRCr8
mRatBN7.21534,358,170 - 34,407,160 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1534,358,277 - 34,407,060 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1536,229,670 - 36,261,919 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01537,380,301 - 37,412,551 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01535,835,892 - 35,868,141 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01540,496,754 - 40,545,933 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1540,513,342 - 40,545,824 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01544,308,883 - 44,358,084 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41539,317,826 - 39,350,075 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11539,332,153 - 39,365,788 (-)NCBI
Celera1534,076,434 - 34,108,683 (-)NCBICelera
Cytogenetic Map15p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (ISO)
1-naphthyl isothiocyanate  (EXP)
17beta-estradiol  (ISO)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,4-dinitrotoluene  (EXP)
2-palmitoylglycerol  (ISO)
3-chloropropane-1,2-diol  (EXP)
3H-1,2-dithiole-3-thione  (EXP)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
all-trans-retinoic acid  (ISO)
ammonium chloride  (EXP)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bisphenol A  (EXP,ISO)
caffeine  (ISO)
cisplatin  (ISO)
clofibric acid  (EXP)
cobalt dichloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
crocidolite asbestos  (ISO)
cyclosporin A  (ISO)
dibenz[a,h]anthracene  (EXP)
dibenzo[a,l]pyrene  (EXP)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (EXP)
dorsomorphin  (ISO)
endosulfan  (ISO)
fenvalerate  (EXP)
flavonoids  (EXP)
fluoranthene  (EXP)
genistein  (ISO)
hydrogen peroxide  (ISO)
indometacin  (EXP)
ivermectin  (ISO)
ketamine  (EXP)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
methotrexate  (ISO)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
methylparaben  (ISO)
N(6)-dimethylallyladenine  (ISO)
N-nitrosodiethylamine  (EXP,ISO)
nitrates  (ISO)
oxaliplatin  (EXP)
paracetamol  (ISO)
phenobarbital  (ISO)
pyrogallol  (ISO)
resveratrol  (ISO)
rotenone  (EXP)
SB 431542  (ISO)
sodium arsenite  (ISO)
sodium dichromate  (EXP)
sunitinib  (ISO)
tert-butyl hydroperoxide  (ISO)
tetrachloromethane  (EXP,ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
topotecan  (EXP)
trichostatin A  (ISO)
trimellitic anhydride  (ISO)
troglitazone  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Gradient of increasing affinity of importin beta for nucleoporins along the pathway of nuclear import. Ben-Efraim I and Gerace L, J Cell Biol. 2001 Jan 22;152(2):411-7.
2. Regulation of mRNA trafficking by nuclear pore complexes. Bonnet A and Palancade B, Genes (Basel). 2014 Sep 2;5(3):767-91. doi: 10.3390/genes5030767.
3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4. Structural analysis of the p62 complex, an assembly of O-linked glycoproteins that localizes near the central gated channel of the nuclear pore complex. Guan T, etal., Mol Biol Cell. 1995 Nov;6(11):1591-603.
5. cDNA cloning and analysis of the expression of nucleoporin p45. Hu T and Gerace L, Gene 1998 Oct 23;221(2):245-53.
6. Molecular and functional characterization of the p62 complex, an assembly of nuclear pore complex glycoproteins. Hu T, etal., J Cell Biol 1996 Aug;134(3):589-601.
7. Allosteric Regulation in Gating the Central Channel of the Nuclear Pore Complex. Koh J and Blobel G, Cell. 2015 Jun 4;161(6):1361-73. doi: 10.1016/j.cell.2015.05.013.
8. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
10. Molecular architecture of the transport channel of the nuclear pore complex. Solmaz SR, etal., Cell. 2011 Oct 28;147(3):590-602. doi: 10.1016/j.cell.2011.09.034.
11. The stoichiometry of the nucleoporin 62 subcomplex of the nuclear pore in solution. Ulrich A, etal., Mol Biol Cell. 2014 May;25(9):1484-92. doi: 10.1091/mbc.E13-12-0745. Epub 2014 Feb 26.
Additional References at PubMed
PMID:12477932   PMID:15489334   PMID:17379812   PMID:26025361  


Genomics

Comparative Map Data
Nup58
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81538,534,340 - 38,583,959 (-)NCBIGRCr8
mRatBN7.21534,358,170 - 34,407,160 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1534,358,277 - 34,407,060 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1536,229,670 - 36,261,919 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01537,380,301 - 37,412,551 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01535,835,892 - 35,868,141 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01540,496,754 - 40,545,933 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1540,513,342 - 40,545,824 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01544,308,883 - 44,358,084 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41539,317,826 - 39,350,075 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11539,332,153 - 39,365,788 (-)NCBI
Celera1534,076,434 - 34,108,683 (-)NCBICelera
Cytogenetic Map15p12NCBI
NUP58
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381325,301,625 - 25,349,800 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1325,301,524 - 25,365,390 (+)EnsemblGRCh38hg38GRCh38
GRCh371325,875,763 - 25,923,938 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361324,773,666 - 24,814,561 (+)NCBINCBI36Build 36hg18NCBI36
Build 341324,773,665 - 24,814,561NCBI
Celera136,939,918 - 6,980,809 (+)NCBICelera
Cytogenetic Map13q12.13NCBI
HuRef136,690,062 - 6,730,691 (+)NCBIHuRef
CHM1_11325,843,885 - 25,884,759 (+)NCBICHM1_1
T2T-CHM13v2.01324,511,318 - 24,559,471 (+)NCBIT2T-CHM13v2.0
Nup58
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391460,442,733 - 60,488,951 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1460,442,731 - 60,488,956 (-)EnsemblGRCm39 Ensembl
GRCm39 Ensembl1460,422,061 - 60,488,880 (-)EnsemblGRCm39 Ensembl
GRCm381460,205,284 - 60,251,479 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1460,205,282 - 60,251,507 (-)EnsemblGRCm38mm10GRCm38
GRCm38.p6 Ensembl1460,184,612 - 60,251,431 (-)EnsemblGRCm38mm10GRCm38
MGSCv371460,838,305 - 60,870,215 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361459,173,578 - 59,205,488 (-)NCBIMGSCv36mm8
Celera1458,009,157 - 58,041,065 (-)NCBICelera
Cytogenetic Map14D1NCBI
cM Map1431.62NCBI
Nup58
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554974,762,316 - 4,830,547 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554974,762,316 - 4,830,320 (+)NCBIChiLan1.0ChiLan1.0
NUP58
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21424,896,010 - 24,946,435 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11316,006,071 - 16,056,478 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0136,593,682 - 6,634,397 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11324,944,910 - 24,985,657 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1324,948,081 - 24,992,854 (+)Ensemblpanpan1.1panPan2
NUP58
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12514,106,135 - 14,158,518 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2514,106,187 - 14,158,464 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2514,185,956 - 14,238,412 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02514,236,442 - 14,289,531 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2514,236,494 - 14,289,555 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12514,118,744 - 14,171,646 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02514,120,919 - 14,173,588 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02514,169,367 - 14,222,519 (-)NCBIUU_Cfam_GSD_1.0
Nup58
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404945116,363,560 - 116,413,033 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936688985,746 - 1,025,407 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936688986,037 - 1,025,351 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NUP58
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl113,225,268 - 3,259,427 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1113,225,185 - 3,266,163 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2112,493,997 - 2,499,480 (-)NCBISscrofa10.2Sscrofa10.2susScr3
NUP58
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.134,695,071 - 4,743,659 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl34,695,137 - 4,737,195 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605739,706,724 - 39,748,086 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Nup58
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462477613,149,019 - 13,219,370 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462477613,149,918 - 13,219,571 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Nup58
102 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:1543
Count of miRNA genes:360
Interacting mature miRNAs:512
Transcripts:ENSRNOT00000017204, ENSRNOT00000063943
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1331729Rf42Renal function QTL 423.071kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)151736289773690657Rat
1641887Alcrsp14Alcohol response QTL 14response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)15142356671Rat
10755503Bp391Blood pressure QTL 3912.37arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)152024860037896129Rat
1582227Gluco30Glucose level QTL 303.60.0003blood glucose amount (VT:0000188)absolute change in blood glucose level area under curve (CMO:0002034)152803066582262678Rat
1582228Epfw3Epididymal fat weight QTL 34.10.0002epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)152803066582262678Rat
1578646Bmd18Bone mineral density QTL 185.2femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)152280624098288169Rat
9589149Insul29Insulin level QTL 299.060.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)15134723002Rat
1578647Bmd17Bone mineral density QTL 174femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)152280624098288169Rat
10401805Kidm51Kidney mass QTL 51kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)1530632945306329Rat
2293686Bmd36Bone mineral density QTL 367.40.0001femur strength trait (VT:0010010)femoral neck ultimate force (CMO:0001703)153361105871477291Rat
2317750Glom26Glomerulus QTL 264.3urine protein amount (VT:0005160)urine protein level (CMO:0000591)151249614165205939Rat
2298549Neuinf12Neuroinflammation QTL 123.5nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)15155302115Rat
2293691Bmd37Bone mineral density QTL 376.60.0001femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)153361105871477291Rat
8552920Pigfal8Plasma insulin-like growth factor 1 level QTL 83blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)15134723002Rat
2293688Bss29Bone structure and strength QTL 295.310.0001femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)151111114256111142Rat
8694361Abfw6Abdominal fat weight QTL 610.20.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)15134723002Rat
1582214Stl21Serum triglyceride level QTL 213.10.022blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)152803066582262678Rat
631273Lecl2Lens clarity QTL 20.001lens clarity trait (VT:0001304)age of onset/diagnosis of cataract (CMO:0001584)151059608955596089Rat
2300167Bmd63Bone mineral density QTL 635.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)151111114256111142Rat
731170Pur3Proteinuria QTL 32.30.0005urine protein amount (VT:0005160)urine protein excretion rate (CMO:0000759)15141686771Rat
738017Hcas7Hepatocarcinoma susceptibility QTL 72.91liver integrity trait (VT:0010547)liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)15226636846921453Rat
152025253Hrtrt24Heart rate QTL 243.82heart pumping trait (VT:2000009)152788577486257085Rat
10054130Srcrt8Stress Responsive Cort QTL 82.180.0085blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)152211793367117933Rat
2300173Bmd62Bone mineral density QTL 6212.80.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)151111114256111142Rat
2324620Coatc3Coat color QTL 3coat/hair pigmentation trait (VT:0010463)pigmented coat/hair area to total coat/hair area ratio (CMO:0001810)151985656646187442Rat
61424Scl1Serum cholesterol level QTL 17.70.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)151672552880672115Rat
1582251Gluco24Glucose level QTL 243.20.0008blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)15553075650530756Rat
1598828Glom14Glomerulus QTL 142.5kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)153405413979054139Rat
631550Bw7Body weight QTL 73.6body mass (VT:0001259)body weight (CMO:0000012)151985656634924750Rat
1582242Gluco28Glucose level QTL 283.30.0008blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)152803066582262678Rat
1578660Bss19Bone structure and strength QTL 194.3femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)152280624098288169Rat
1582244Bw79Body weight QTL 7940.0002epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)152803066582262678Rat

Markers in Region
RH131539  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21534,379,545 - 34,379,727 (+)MAPPERmRatBN7.2
Rnor_6.01540,518,132 - 40,518,313NCBIRnor6.0
Rnor_5.01544,330,244 - 44,330,425UniSTSRnor5.0
RGSC_v3.41539,322,620 - 39,322,801UniSTSRGSC3.4
Celera1534,081,228 - 34,081,409UniSTS
RH 3.4 Map15229.1UniSTS
Cytogenetic Map15p12UniSTS
RH144130  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21534,373,420 - 34,373,657 (+)MAPPERmRatBN7.2
Rnor_6.01540,512,007 - 40,512,243NCBIRnor6.0
Rnor_5.01544,324,119 - 44,324,355UniSTSRnor5.0
RGSC_v3.41539,316,495 - 39,316,731UniSTSRGSC3.4
Celera1534,075,103 - 34,075,339UniSTS
RH 3.4 Map15220.4UniSTS
Cytogenetic Map15p12UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000017204   ⟹   ENSRNOP00000017204
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1534,358,277 - 34,407,060 (-)Ensembl
Rnor_6.0 Ensembl1540,513,342 - 40,545,824 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000063943   ⟹   ENSRNOP00000063452
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1534,376,778 - 34,406,940 (-)Ensembl
Rnor_6.0 Ensembl1540,518,043 - 40,542,495 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000095956   ⟹   ENSRNOP00000084647
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1534,373,383 - 34,407,060 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000101273   ⟹   ENSRNOP00000078538
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1534,373,383 - 34,407,060 (-)Ensembl
RefSeq Acc Id: NM_139091   ⟹   NP_620791
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81538,550,916 - 38,583,165 (-)NCBI
mRatBN7.21534,374,752 - 34,407,003 (-)NCBI
Rnor_6.01540,513,338 - 40,545,824 (-)NCBI
Rnor_5.01544,308,883 - 44,358,084 (-)NCBI
RGSC_v3.41539,317,826 - 39,350,075 (-)RGD
Celera1534,076,434 - 34,108,683 (-)RGD
Sequence:
RefSeq Acc Id: XM_006252093   ⟹   XP_006252155
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81538,534,340 - 38,583,959 (-)NCBI
mRatBN7.21534,358,170 - 34,407,158 (-)NCBI
Rnor_6.01540,496,754 - 40,545,933 (-)NCBI
Rnor_5.01544,308,883 - 44,358,084 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039092981   ⟹   XP_038948909
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81538,549,542 - 38,583,333 (-)NCBI
mRatBN7.21534,373,378 - 34,407,158 (-)NCBI
RefSeq Acc Id: XM_039092982   ⟹   XP_038948910
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81538,534,340 - 38,583,959 (-)NCBI
mRatBN7.21534,358,170 - 34,407,160 (-)NCBI
RefSeq Acc Id: NP_620791   ⟸   NM_139091
- UniProtKB: Q9QWK7 (UniProtKB/Swiss-Prot),   Q9JHE1 (UniProtKB/Swiss-Prot),   Q9Z2W7 (UniProtKB/Swiss-Prot),   P70581 (UniProtKB/Swiss-Prot),   A6K695 (UniProtKB/TrEMBL),   A0A8I6G353 (UniProtKB/TrEMBL),   A6K694 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006252155   ⟸   XM_006252093
- Peptide Label: isoform X2
- UniProtKB: A0A8L2Q9I5 (UniProtKB/TrEMBL),   A6K693 (UniProtKB/TrEMBL),   A6K694 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000063452   ⟸   ENSRNOT00000063943
Ensembl Acc Id: ENSRNOP00000017204   ⟸   ENSRNOT00000017204
RefSeq Acc Id: XP_038948910   ⟸   XM_039092982
- Peptide Label: isoform X3
- UniProtKB: A6K694 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038948909   ⟸   XM_039092981
- Peptide Label: isoform X1
- UniProtKB: A6K694 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000078538   ⟸   ENSRNOT00000101273
Ensembl Acc Id: ENSRNOP00000084647   ⟸   ENSRNOT00000095956

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P70581-F1-model_v2 AlphaFold P70581 1-585 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699734
Promoter ID:EPDNEW_R10257
Type:multiple initiation site
Name:Nup58_1
Description:nucleoporin 58
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01540,545,858 - 40,545,918EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:631334 AgrOrtholog
BioCyc Gene G2FUF-13535 BioCyc
Ensembl Genes ENSRNOG00000012644 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000017204 ENTREZGENE
  ENSRNOT00000063943.3 UniProtKB/Swiss-Prot
  ENSRNOT00000095956 ENTREZGENE
  ENSRNOT00000095956.1 UniProtKB/Swiss-Prot
  ENSRNOT00000101273 ENTREZGENE
Gene3D-CATH 6.10.140.1350 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7190650 IMAGE-MGC_LOAD
InterPro Nucleoporin_p58/p45 UniProtKB/Swiss-Prot
KEGG Report rno:245922 UniProtKB/Swiss-Prot
MGC_CLONE MGC:93109 IMAGE-MGC_LOAD
NCBI Gene 245922 ENTREZGENE
PANTHER NUCLEOPORIN P58/P45 UniProtKB/Swiss-Prot
  PTHR13437 UniProtKB/Swiss-Prot
Pfam Nucleoporin_FG2 UniProtKB/Swiss-Prot
PhenoGen Nup58 PhenoGen
RatGTEx ENSRNOG00000012644 RatGTEx
UniProt A0A8I6G353 ENTREZGENE, UniProtKB/TrEMBL
  A0A8L2Q9I5 ENTREZGENE, UniProtKB/TrEMBL
  A6K693 ENTREZGENE, UniProtKB/TrEMBL
  A6K694 ENTREZGENE, UniProtKB/TrEMBL
  A6K695 ENTREZGENE, UniProtKB/TrEMBL
  D3ZVG3_RAT UniProtKB/TrEMBL
  NUP58_RAT UniProtKB/Swiss-Prot, ENTREZGENE
  Q9JHE1 ENTREZGENE
  Q9QWK7 ENTREZGENE
  Q9Z2W7 ENTREZGENE
UniProt Secondary Q9JHE1 UniProtKB/Swiss-Prot
  Q9QWK7 UniProtKB/Swiss-Prot
  Q9Z2W7 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-08-19 Nup58  nucleoporin 58  Nupl1  nucleoporin like 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-09-10 Nupl1  nucleoporin like 1  p58/p45  nucleoporin p58  Symbol and Name updated 1299863 APPROVED