Slc13a3 (solute carrier family 13 member 3) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Slc13a3 (solute carrier family 13 member 3) Rattus norvegicus
Analyze
Symbol: Slc13a3
Name: solute carrier family 13 member 3
RGD ID: 628786
Description: Enables carboxylic acid transmembrane transporter activity. Involved in aspartate transmembrane transport; citrate transport; and succinate transmembrane transport. Predicted to be located in basolateral plasma membrane. Predicted to be active in plasma membrane. Orthologous to human SLC13A3 (solute carrier family 13 member 3); INTERACTS WITH (+)-schisandrin B; 1,3-dinitrobenzene; 17beta-estradiol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: Na(+)-coupled carboxylate transporter 3; Na(+)/dicarboxylate cotransporter 3; NaC3; naDC-3; Nadc3; rNaDC3; SDCT2; sodium-dependent high-affinity dicarboxylate transporter 2; sodium-dependent high-affinity dicarboxylate transporter 3; solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Candidate Gene For: Eau4
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83174,561,174 - 174,623,893 (-)NCBIGRCr8
mRatBN7.23154,141,878 - 154,204,604 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3154,141,872 - 154,204,606 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3157,950,554 - 158,014,103 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03166,449,536 - 166,513,085 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03164,191,155 - 164,254,719 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03162,084,336 - 162,147,398 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3162,084,315 - 162,147,393 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03168,266,585 - 168,329,647 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43156,447,900 - 156,510,620 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13156,353,929 - 156,416,658 (-)NCBI
Celera3152,740,642 - 152,803,198 (-)NCBICelera
Cytogenetic Map3q42NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
(1->4)-beta-D-glucan  (ISO)
1,1-dichloroethene  (ISO)
1,2-dichloroethane  (ISO)
1,3-dinitrobenzene  (EXP)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP,ISO)
17beta-estradiol 3-benzoate  (EXP)
2,2',4,4',5,5'-hexachlorobiphenyl  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
2,4-dinitrotoluene  (EXP)
2,6-dinitrotoluene  (EXP)
3,3',4,4',5-pentachlorobiphenyl  (EXP)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
5-aza-2'-deoxycytidine  (ISO)
6-propyl-2-thiouracil  (EXP)
7,12-dimethyltetraphene  (EXP)
acrolein  (EXP)
acrylamide  (ISO)
aflatoxin B1  (ISO)
alpha-Zearalanol  (EXP)
ammonium chloride  (EXP)
arsane  (ISO)
arsenic atom  (ISO)
benzo[a]pyrene  (ISO)
bisphenol A  (EXP,ISO)
cadmium dichloride  (ISO)
carbamazepine  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
choline  (ISO)
cisplatin  (ISO)
copper(II) chloride  (ISO)
copper(II) sulfate  (ISO)
Cuprizon  (EXP)
cyclosporin A  (ISO)
cyproconazole  (ISO)
dexamethasone  (EXP)
dichloroacetic acid  (ISO)
diclofenac  (ISO)
dieldrin  (EXP)
diethylstilbestrol  (EXP)
epoxiconazole  (ISO)
ethanol  (ISO)
ether  (EXP)
flutamide  (EXP)
folic acid  (ISO)
gentamycin  (EXP)
glafenine  (EXP)
glyphosate  (EXP)
graphite  (EXP)
GW 4064  (ISO)
indole-3-methanol  (EXP)
isoflurane  (EXP)
L-methionine  (ISO)
lead diacetate  (EXP)
levofloxacin  (EXP)
lidocaine  (EXP)
lipopolysaccharide  (ISO)
Monobutylphthalate  (EXP)
N-nitrosodiethylamine  (EXP,ISO)
nitrofen  (EXP)
okadaic acid  (ISO)
ozone  (ISO)
paracetamol  (EXP,ISO)
pentobarbital  (EXP)
perfluorohexanesulfonic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (EXP)
phenformin  (EXP)
phenobarbital  (ISO)
pirinixic acid  (ISO)
potassium chromate  (ISO)
pravastatin  (ISO)
propanal  (ISO)
propiconazole  (ISO)
quercetin  (ISO)
rotenone  (EXP)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
sodium fluoride  (ISO)
succinic acid  (EXP,ISO)
tamoxifen  (ISO)
tert-butyl hydroperoxide  (ISO)
testosterone  (EXP,ISO)
tetrachloromethane  (EXP,ISO)
thioacetamide  (EXP)
thiram  (ISO)
toluene  (EXP)
trichloroethene  (EXP,ISO)
Triptolide  (EXP,ISO)
trovafloxacin  (ISO)
valproic acid  (EXP,ISO)
vanadyl sulfate  (ISO)
vancomycin  (ISO)
vinclozolin  (EXP)
zaragozic acid A  (EXP,ISO)
zidovudine  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
basolateral plasma membrane  (IEA,ISO)
membrane  (IEA,ISO)
plasma membrane  (IBA,IEA,ISO)

References

References - curated
# Reference Title Reference Citation
1. Molecular and functional analysis of SDCT2, a novel rat sodium-dependent dicarboxylate transporter. Chen X, etal., J Clin Invest 1999 Apr;103(8):1159-68.
2. Transport characteristics of N-acetyl-L-aspartate in rat astrocytes: involvement of sodium-coupled high-affinity carboxylate transporter NaC3/NaDC3-mediated transport system. Fujita T, etal., J Neurochem. 2005 May;93(3):706-14.
3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4. Transport of N-acetylaspartate by the Na(+)-dependent high-affinity dicarboxylate transporter NaDC3 and its relevance to the expression of the transporter in the brain. Huang W, etal., J Pharmacol Exp Ther. 2000 Oct;295(1):392-403.
5. Structure, function, and expression pattern of a novel sodium-coupled citrate transporter (NaCT) cloned from mammalian brain. Inoue K, etal., J Biol Chem 2002 Oct 18;277(42):39469-76.
6. Primary structure and functional characteristics of a mammalian sodium-coupled high affinity dicarboxylate transporter. Kekuda R, etal., J Biol Chem 1999 Feb 5;274(6):3422-9.
7. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
8. GOA pipeline RGD automated data pipeline
9. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
10. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
11. Functional and molecular identification of sodium-coupled dicarboxylate transporters in rat primary cultured cerebrocortical astrocytes and neurons. Yodoya E, etal., J Neurochem. 2006 Apr;97(1):162-73. Epub 2006 Mar 8.
Additional References at PubMed
PMID:11287335   PMID:12477932   PMID:19056867   PMID:20813124   PMID:21264516   PMID:22871113   PMID:24247155   PMID:27053689   PMID:30635937  


Genomics

Comparative Map Data
Slc13a3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83174,561,174 - 174,623,893 (-)NCBIGRCr8
mRatBN7.23154,141,878 - 154,204,604 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3154,141,872 - 154,204,606 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3157,950,554 - 158,014,103 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03166,449,536 - 166,513,085 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03164,191,155 - 164,254,719 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03162,084,336 - 162,147,398 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3162,084,315 - 162,147,393 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03168,266,585 - 168,329,647 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43156,447,900 - 156,510,620 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13156,353,929 - 156,416,658 (-)NCBI
Celera3152,740,642 - 152,803,198 (-)NCBICelera
Cytogenetic Map3q42NCBI
SLC13A3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382046,557,828 - 46,684,485 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2046,557,823 - 46,684,467 (-)EnsemblGRCh38hg38GRCh38
GRCh372045,186,467 - 45,313,124 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362044,619,870 - 44,746,514 (-)NCBINCBI36Build 36hg18NCBI36
Build 342044,619,869 - 44,713,505NCBI
Celera2041,897,908 - 42,024,605 (-)NCBICelera
Cytogenetic Map20q13.12ENTREZGENE
HuRef2041,927,384 - 42,054,359 (-)NCBIHuRef
CHM1_12045,089,076 - 45,216,112 (-)NCBICHM1_1
T2T-CHM13v2.02048,293,974 - 48,420,764 (-)NCBIT2T-CHM13v2.0
Slc13a3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392165,247,215 - 165,315,117 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2165,246,948 - 165,315,150 (-)EnsemblGRCm39 Ensembl
GRCm382165,405,295 - 165,473,197 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2165,405,028 - 165,473,230 (-)EnsemblGRCm38mm10GRCm38
MGSCv372165,230,795 - 165,298,697 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362165,096,500 - 165,164,402 (-)NCBIMGSCv36mm8
Celera2171,347,492 - 171,415,775 (-)NCBICelera
Cytogenetic Map2H3NCBI
cM Map285.54NCBI
Slc13a3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544510,755,312 - 10,831,900 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495544510,755,336 - 10,829,797 (+)NCBIChiLan1.0ChiLan1.0
SLC13A3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22152,293,088 - 52,405,943 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12052,286,193 - 52,399,047 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02042,890,251 - 43,018,635 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12043,975,373 - 44,101,788 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2043,977,568 - 44,068,886 (-)Ensemblpanpan1.1panPan2
SLC13A3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12433,810,594 - 33,884,169 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2433,809,731 - 33,884,139 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2433,269,702 - 33,344,444 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02434,518,068 - 34,593,024 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2434,518,081 - 34,593,006 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12433,775,187 - 33,849,803 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02433,891,902 - 33,966,700 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02434,430,790 - 34,505,677 (-)NCBIUU_Cfam_GSD_1.0
Slc13a3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640191,100,938 - 191,140,371 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365146,554,608 - 6,592,671 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365146,554,605 - 6,594,014 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SLC13A3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1748,714,183 - 48,792,141 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11748,714,180 - 48,792,280 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21754,563,504 - 54,593,504 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SLC13A3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1217,233,287 - 17,324,761 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl217,233,346 - 17,324,951 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605065,843,126 - 65,967,625 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Slc13a3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247908,028,103 - 8,105,871 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247908,028,054 - 8,104,123 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Slc13a3
514 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:204
Count of miRNA genes:142
Interacting mature miRNAs:166
Transcripts:ENSRNOT00000025843
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
12879876Bw182Body weight QTL 1820.003body mass (VT:0001259)body weight (CMO:0000012)3145925360166177555Rat
2301411Bp320Blood pressure QTL 3200.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)3145925360166177555Rat
2312673Scl63Serum cholesterol level QTL 630.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)398535255168026850Rat
1300113Bp176Blood pressure QTL 1763.9arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)3145956084157309487Rat
12879872Cm97Cardiac mass QTL 970.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)3145925360166177555Rat
1598877Bp285Blood pressure QTL 2851.50.03arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3120538241165538241Rat
1578653Vnigr3Vascular neointimal growth QTL 33.1artery morphology trait (VT:0002191)artery neointimal hyperplastic lesion area (CMO:0001414)3130656562169034231Rat
12879873Cm96Cardiac mass QTL 960.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)3145925360166177555Rat
2302373Gluco39Glucose level QTL 395.01blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)398535386161695835Rat
12879874Cm98Cardiac mass QTL 980.005heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)3145925360166177555Rat
1298068Bp167Blood pressure QTL 1670.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3141074471169034231Rat
12879875Kidm64Kidney mass QTL 640.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)3145925360166177555Rat
70216Cm14Cardiac mass QTL 142.1heart mass (VT:0007028)heart wet weight (CMO:0000069)331172320163586636Rat
2298477Eau4Experimental allergic uveoretinitis QTL 40.0011uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)3137398739169034231Rat
8552791Vie2Viral induced encephalitis QTL 24.1brain integrity trait (VT:0010579)encephalitis incidence/prevalence measurement (CMO:0002361)3145956084169034231Rat
61335Bp20Blood pressure QTL 203arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3141339236155617360Rat
1581568Rf53Renal function QTL 53urine total protein amount (VT:0000032)urine protein excretion rate to body weight ratio (CMO:0001099)356395968161299569Rat
2317883Alcrsp26Alcohol response QTL 261.80.63response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)3145526770169034231Rat
1578754Stresp16Stress response QTL 1640.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)3112681431157681431Rat
1331726Bp208Blood pressure QTL 2083.129arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)3141339013162184794Rat
1598854Memor10Memory QTL 102exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)3145956084161299569Rat
9589106Insul23Insulin level QTL 2313.860.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)3131635904169034231Rat
10755461Coatc16Coat color QTL 16coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)3122438700167438700Rat
8662816Vetf4Vascular elastic tissue fragility QTL 44renal artery integrity trait (VT:0010642)number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563)359242096157323038Rat
1559282Emca5Estrogen-induced mammary cancer QTL 53.9mammary gland integrity trait (VT:0010552)percentage of study population developing mammary tumors during a period of time (CMO:0000948)343827364169034231Rat
2303620Vencon4Ventilatory control QTL 43.9respiration trait (VT:0001943)tidal volume (CMO:0000222)3127162703168026850Rat
631841Niddm39Non-insulin dependent diabetes mellitus QTL 393.36blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)394856903159898684Rat
1576306Schws3Schwannoma susceptibility QTL 30.001nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)3118839124163839124Rat
1300159Kidm4Kidney mass QTL 43.83kidney mass (VT:0002707)right kidney wet weight to body weight ratio (CMO:0001953)3121056165157309487Rat
2301971Cm71Cardiac mass QTL 714.63heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)341874578155617519Rat
2312659Slep7Serum leptin concentration QTL 70.001blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)398535255168026850Rat
631673Iddm13Insulin dependent diabetes mellitus QTL 131.30.663blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)3130193298161695983Rat
2301970Bw81Body weight QTL 815.19body mass (VT:0001259)body weight (CMO:0000012)341874578155617519Rat
1578666Vnigr1Vascular neointimal growth QTL 14.6artery morphology trait (VT:0002191)artery lumen area (CMO:0001409)3149040888168026850Rat
1578656Vnigr2Vascular neointimal growth QTL 24.2artery morphology trait (VT:0002191)lesioned artery residual lumen area (CMO:0001417)3130656562169034231Rat
8552952Pigfal13Plasma insulin-like growth factor 1 level QTL 13blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)3138799500169034231Rat
12879871Am7Aortic mass QTL 70.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)3145925360166177555Rat
631541Bp81Blood pressure QTL 814arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3124122556169034231Rat
2312670Bw94Body weight QTL 940.01inguinal fat pad mass (VT:0010424)inguinal fat pad weight to body weight ratio (CMO:0001253)398535255168026850Rat

Markers in Region
RH130357  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23154,142,035 - 154,142,231 (+)MAPPERmRatBN7.2
Rnor_6.03162,084,494 - 162,084,689NCBIRnor6.0
Rnor_5.03168,266,743 - 168,266,938UniSTSRnor5.0
RGSC_v3.43156,448,058 - 156,448,253UniSTSRGSC3.4
Celera3152,740,800 - 152,740,995UniSTS
RH 3.4 Map31394.1UniSTS
Cytogenetic Map3q42UniSTS
stSG607484  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23154,172,331 - 154,173,814 (+)MAPPERmRatBN7.2
Rnor_6.03162,114,960 - 162,116,442NCBIRnor6.0
Rnor_5.03168,297,209 - 168,298,691UniSTSRnor5.0
RGSC_v3.43156,478,350 - 156,479,832UniSTSRGSC3.4
Celera3152,770,573 - 152,772,055UniSTS
Cytogenetic Map3q42UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
8 11 45 113 91 89 59 22 59 6 209 89 93 45 60 30

Sequence


Ensembl Acc Id: ENSRNOT00000025843   ⟹   ENSRNOP00000025843
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3154,141,872 - 154,204,606 (-)Ensembl
Rnor_6.0 Ensembl3162,084,315 - 162,147,393 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000115401   ⟹   ENSRNOP00000078047
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3154,141,872 - 154,182,056 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000119735   ⟹   ENSRNOP00000096412
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3154,141,872 - 154,204,606 (-)Ensembl
RefSeq Acc Id: NM_022866   ⟹   NP_074057
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83174,561,174 - 174,623,893 (-)NCBI
mRatBN7.23154,141,878 - 154,204,604 (-)NCBI
Rnor_6.03162,084,336 - 162,147,398 (-)NCBI
Rnor_5.03168,266,585 - 168,329,647 (-)NCBI
RGSC_v3.43156,447,900 - 156,510,620 (-)RGD
Celera3152,740,642 - 152,803,198 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_074057 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAD16019 (Get FASTA)   NCBI Sequence Viewer  
  AAD30657 (Get FASTA)   NCBI Sequence Viewer  
  AAI29095 (Get FASTA)   NCBI Sequence Viewer  
  EDL96454 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000025843
GenBank Protein Q9Z0Z5 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_074057   ⟸   NM_022866
- UniProtKB: Q9Z0Z5 (UniProtKB/Swiss-Prot),   A2VD10 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000025843   ⟸   ENSRNOT00000025843
Ensembl Acc Id: ENSRNOP00000078047   ⟸   ENSRNOT00000115401
Ensembl Acc Id: ENSRNOP00000096412   ⟸   ENSRNOT00000119735

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9Z0Z5-F1-model_v2 AlphaFold Q9Z0Z5 1-600 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13692678
Promoter ID:EPDNEW_R3202
Type:single initiation site
Name:Slc13a3_1
Description:solute carrier family 13 member 3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.03162,147,403 - 162,147,463EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:628786 AgrOrtholog
BioCyc Gene G2FUF-46799 BioCyc
Ensembl Genes ENSRNOG00000019118 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000025843 ENTREZGENE
IMAGE_CLONE IMAGE:8365494 IMAGE-MGC_LOAD
InterPro SLC13A/DASS UniProtKB/Swiss-Prot
MGC_CLONE MGC:156643 IMAGE-MGC_LOAD
NCBI Gene 64846 ENTREZGENE
PANTHER SOLUTE CARRIER FAMILY 13 MEMBER UniProtKB/Swiss-Prot
  SOLUTE CARRIER FAMILY 13 MEMBER 3 UniProtKB/Swiss-Prot
Pfam Na_sulph_symp UniProtKB/Swiss-Prot
PhenoGen Slc13a3 PhenoGen
RatGTEx ENSRNOG00000019118 RatGTEx
UniProt A0A8I5Y6T4_RAT UniProtKB/TrEMBL
  A0A8I6AV19_RAT UniProtKB/TrEMBL
  A2VD10 ENTREZGENE, UniProtKB/TrEMBL
  A6JXF5_RAT UniProtKB/TrEMBL
  Q9Z0Z5 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-02-25 Slc13a3  solute carrier family 13 member 3  Slc13a3  solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-09-10 Slc13a3  solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3      Symbol and Name status set to approved 1299863 APPROVED
2003-02-27 Slc13a3        Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_expression mRNA expression in kidney, liver, and brain 634020