Lrrcc1 (leucine rich repeat and coiled-coil centrosomal protein 1) - Rat Genome Database

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Gene: Lrrcc1 (leucine rich repeat and coiled-coil centrosomal protein 1) Rattus norvegicus
Analyze
Symbol: Lrrcc1
Name: leucine rich repeat and coiled-coil centrosomal protein 1
RGD ID: 628722
Description: Predicted to be active in centrosome and cytoplasm. Orthologous to human LRRCC1 (leucine rich repeat and coiled-coil centrosomal protein 1); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-diaminodiphenylmethane; acetamide.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: leucine rich repeat and coiled-coil domain containing 1; leucine-rich repeat and coiled-coil domain-containing protein 1; Sap2; sodium channel associated protein 2; sodium channel associated protein 2, Sap2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8288,746,904 - 88,781,532 (-)NCBIGRCr8
mRatBN7.2287,025,671 - 87,060,313 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl287,025,598 - 87,060,294 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx293,361,670 - 93,389,805 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0291,482,683 - 91,510,820 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0286,539,493 - 86,567,630 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0288,384,796 - 88,414,012 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl288,384,796 - 88,414,012 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02108,155,195 - 108,184,411 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4288,382,415 - 88,410,482 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1288,337,222 - 88,346,263 (-)NCBI
Celera282,622,863 - 82,823,739 (-)NCBICelera
Cytogenetic Map2q23NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
centrosome  (IBA,ISO)
cytoplasm  (IBA)

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
5. Information Derived from GenBank Report RGD, Sept. 2003
Additional References at PubMed
PMID:8889548   PMID:12060780   PMID:21399614  


Genomics

Comparative Map Data
Lrrcc1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8288,746,904 - 88,781,532 (-)NCBIGRCr8
mRatBN7.2287,025,671 - 87,060,313 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl287,025,598 - 87,060,294 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx293,361,670 - 93,389,805 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0291,482,683 - 91,510,820 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0286,539,493 - 86,567,630 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0288,384,796 - 88,414,012 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl288,384,796 - 88,414,012 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02108,155,195 - 108,184,411 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4288,382,415 - 88,410,482 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1288,337,222 - 88,346,263 (-)NCBI
Celera282,622,863 - 82,823,739 (-)NCBICelera
Cytogenetic Map2q23NCBI
LRRCC1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38885,107,238 - 85,146,080 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl885,107,215 - 85,146,080 (+)EnsemblGRCh38hg38GRCh38
GRCh37886,019,473 - 86,058,315 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36886,206,629 - 86,245,567 (+)NCBINCBI36Build 36hg18NCBI36
Celera882,024,953 - 82,063,634 (+)NCBICelera
Cytogenetic Map8q21.2NCBI
HuRef881,512,573 - 81,552,589 (+)NCBIHuRef
CHM1_1886,070,851 - 86,109,890 (+)NCBICHM1_1
T2T-CHM13v2.0885,545,871 - 85,584,696 (+)NCBIT2T-CHM13v2.0
Lrrcc1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39314,595,512 - 14,637,718 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl314,598,848 - 14,637,718 (+)EnsemblGRCm39 Ensembl
GRCm38314,533,762 - 14,572,658 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl314,533,788 - 14,572,658 (+)EnsemblGRCm38mm10GRCm38
MGSCv37314,533,788 - 14,572,658 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36314,510,532 - 14,549,387 (+)NCBIMGSCv36mm8
Celera314,542,159 - 14,580,814 (+)NCBICelera
Cytogenetic Map3A1NCBI
cM Map33.08NCBI
Lrrcc1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554173,082,822 - 3,115,136 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554173,082,821 - 3,115,136 (+)NCBIChiLan1.0ChiLan1.0
LRRCC1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v27100,845,694 - 100,888,148 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1876,478,298 - 76,520,723 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0881,638,782 - 81,678,288 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1883,250,077 - 83,287,999 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl883,250,077 - 83,287,999 (+)Ensemblpanpan1.1panPan2
LRRCC1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12931,677,938 - 31,716,282 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2931,678,261 - 31,715,611 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2931,960,784 - 31,999,162 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02931,827,152 - 31,865,733 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2931,827,463 - 31,865,126 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12931,882,337 - 31,920,509 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02931,900,540 - 31,938,739 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02932,284,183 - 32,322,561 (+)NCBIUU_Cfam_GSD_1.0
Lrrcc1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530347,678,726 - 47,714,249 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493654478,440 - 114,314 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493654478,450 - 114,341 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LRRCC1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl451,525,047 - 51,570,425 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1451,525,044 - 51,570,609 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2456,543,433 - 56,589,374 (-)NCBISscrofa10.2Sscrofa10.2susScr3
LRRCC1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1880,472,236 - 80,513,924 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl880,472,931 - 80,514,538 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603960,585,945 - 60,627,140 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Lrrcc1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247446,513,920 - 6,549,776 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247446,512,963 - 6,549,901 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Lrrcc1
287 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:37
Count of miRNA genes:31
Interacting mature miRNAs:31
Transcripts:ENSRNOT00000014762
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
61355Bp36Blood pressure QTL 362.9blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)25873687102844969Rat
1302794Stl27Serum triglyceride level QTL 274.40.0001blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)225413423143657569Rat
1358894Kidm24Kidney mass QTL 244.03kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)225413423157142209Rat
1358899Kidm23Kidney mass QTL 233.88kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)225413423157142209Rat
1358901Cm38Cardiac mass QTL 382heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)225413423157142209Rat
1358904Cm39Cardiac mass QTL 392.26heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)225413423157142209Rat
1358910Kidm27Kidney mass QTL 275.77kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)225413423157142209Rat
1358911Kidm28Kidney mass QTL 285.42kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)225413423157142209Rat
1358913Cm41Cardiac mass QTL 412.73heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)225413423203928301Rat
1358917Cm42Cardiac mass QTL 422.82heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)225413423203928301Rat
1358887Bw50Body weight QTL 502.39body mass (VT:0001259)body weight (CMO:0000012)225413652157142078Rat
1358908Bw49Body weight QTL 493.36body mass (VT:0001259)body weight (CMO:0000012)225413652157142078Rat
1354603Bp243Blood pressure QTL 2433.9arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)226917817127469484Rat
2290453Scl55Serum cholesterol level QTL 552.83blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)226917817136917119Rat
61371Edpm1Estrogen-dependent pituitary mass QTL 140.05pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)23513484188029593Rat
70174BpQTLCluster2Blood pressure QTL cluster 24.24arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)240067944102785628Rat
70174BpQTLCluster2Blood pressure QTL cluster 24.24arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)240067944102785628Rat
70174BpQTLCluster2Blood pressure QTL cluster 24.24arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)240067944102785628Rat
70174BpQTLCluster2Blood pressure QTL cluster 24.24arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)240067944102785628Rat
70174BpQTLCluster2Blood pressure QTL cluster 24.24arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)240067944102785628Rat
2293835Kiddil5Kidney dilation QTL 53.8kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)242804607157142209Rat
2293843Kiddil6Kidney dilation QTL 63.1kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)242804607182042367Rat
1298074Bp164Blood pressure QTL 1640.003arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)242804607202447032Rat
1298085Bp165Blood pressure QTL 1650.0006arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)242804607202447032Rat
61467Bp14Blood pressure QTL 142.2arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)243154682202446871Rat
61467Bp14Blood pressure QTL 142.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)243154682202446871Rat
2293676Bmd19Bone mineral density QTL 1910.70.0001femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)243162366111362592Rat
2293682Bmd24Bone mineral density QTL 248.90.0001femur mineral mass (VT:0010011)compact volumetric bone mineral density (CMO:0001730)243162366111362592Rat
2293671Bss44Bone structure and strength QTL 4410.970.0001lumbar vertebra morphology trait (VT:0010494)lumbar vertebra cortical cross-sectional area (CMO:0001690)243162366148478373Rat
1354601Slep1Serum leptin concentration QTL 15.39blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)243171017184114403Rat
631266Bp132Blood pressure QTL 1320.0005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)246123260202447032Rat
1331760Bp206Blood pressure QTL 2063.62454arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)256043031202447032Rat
1558648Smcn1Smooth muscle cell number QTL 10.039blood vessel smooth muscle cell quantity (VT:0010525)aorta smooth muscle cell count per unit vessel length (CMO:0001646)259134147127460910Rat
5684990Bmd82Bone mineral density QTL 822.8tibia mineral mass (VT:1000283)bone mineral content (CMO:0001554)259324377103795077Rat
5684996Bmd85Bone mineral density QTL 854.70.024tibia mineral mass (VT:1000283)bone mineral density (CMO:0001226)259324377103795077Rat
61438Cia7Collagen induced arthritis QTL 74.60.0001joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)259324377141596857Rat
631500Bp99Blood pressure QTL 992.5arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)259324719102755241Rat
1578777Stresp15Stress response QTL 1520.05blood aldosterone amount (VT:0005346)plasma aldosterone level (CMO:0000551)259846005104846005Rat
2306903Bp336Blood pressure QTL 3360.01arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)264366971109366971Rat
1298080Bp163Blood pressure QTL 1630.02arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)266118275202447032Rat
1354648Bp239Blood pressure QTL 2390.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)266118463226797303Rat
7411551Bw131Body weight QTL 13129.60.001body mass (VT:0001259)body weight gain (CMO:0000420)267942638112942638Rat
1558653Prcr1Prostate cancer resistance QTL 15prostate integrity trait (VT:0010571)area of ventral prostate occupied by tumorous lesions to total ventral prostate area ratio (CMO:0000899)272532993157142209Rat
1359034Bp274Blood pressure QTL 274arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)27478666494359546Rat
1359034Bp274Blood pressure QTL 274arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)27478666494359546Rat
1354605Rf48Renal function QTL 482.9blood creatinine amount (VT:0005328)plasma creatinine level (CMO:0000537)274786664206665859Rat
61465Bp13Blood pressure QTL 133.3blood pressure trait (VT:0000183)diastolic blood pressure (CMO:0000005)276539322102785628Rat
61465Bp13Blood pressure QTL 133.3blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)276539322102785628Rat
631198Cm22Cardiac mass QTL 224.30.0008heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)276539322150540526Rat
61374Edpm2Estrogen-dependent pituitary mass QTL 24.420.86pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)276539322202447032Rat
2299162Iddm32Insulin dependent diabetes mellitus QTL 322.36blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)278665616143657569Rat
1581569Uae32Urinary albumin excretion QTL 320.0001urine protein amount (VT:0005160)urine albumin excretion rate (CMO:0000757)278665619219826953Rat
724534Uae6Urinary albumin excretion QTL 610urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)278665619249053267Rat
61392Bp6Blood pressure QTL 67arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)280270434125270434Rat
1598865Bp296Blood pressure QTL 2962.1arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)281018907126018907Rat
8662832Vetf7Vascular elastic tissue fragility QTL 73.5aorta elastin amount (VT:0003905)aorta wall extracellular elastin dry weight to aorta wall dry weight ratio (CMO:0002002)281689826221035911Rat
1354622Kidm16Kidney mass QTL 163kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)281754530222436696Rat
1354649Kidm17Kidney mass QTL 172.9kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)281754530227146641Rat
1578772Stresp14Stress response QTL 1450.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)282345893130923501Rat

Markers in Region
BE114190  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2287,050,162 - 87,050,312 (+)MAPPERmRatBN7.2
Rnor_6.0288,402,889 - 88,403,038NCBIRnor6.0
Rnor_5.02108,173,288 - 108,173,437UniSTSRnor5.0
RGSC_v3.4288,572,882 - 88,573,032UniSTSRGSC3.4
RGSC_v3.4288,400,512 - 88,400,661UniSTSRGSC3.4
Celera282,807,033 - 82,807,183UniSTS
Celera282,640,954 - 82,641,104UniSTS
RH 3.4 Map2534.6UniSTS
Cytogenetic Map2q23UniSTS
AU048266  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.0288,410,257 - 88,410,371NCBIRnor6.0
Rnor_5.02108,180,656 - 108,180,770UniSTSRnor5.0
RGSC_v3.4288,406,785 - 88,406,897UniSTSRGSC3.4
Celera282,819,954 - 82,820,094UniSTS
Cytogenetic Map2q23UniSTS
AI232130  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.0288,740,418 - 88,740,530NCBIRnor6.0
Rnor_5.02108,512,820 - 108,512,932UniSTSRnor5.0
RGSC_v3.4288,756,502 - 88,756,614UniSTSRGSC3.4
RGSC_v3.4288,553,538 - 88,553,650UniSTSRGSC3.4
Celera282,792,341 - 82,792,453UniSTS
Celera282,978,372 - 82,978,484UniSTS
RH 3.4 Map2543.4UniSTS
Cytogenetic Map2q23UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 14 28 16 15 16 66 34 41 11
Low 29 26 22 4 22 8 10 8 1 8
Below cutoff 3 3 3 1

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001100645 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039101805 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039101808 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039101810 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039101811 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039101813 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039101814 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039101815 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AF421192 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BG671381 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BM390666 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BP502994 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CB547116 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CB579146 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473961 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CV126197 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FM039623 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FM040678 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FM134600 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000002 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSRNOT00000014762   ⟹   ENSRNOP00000014762
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl287,032,067 - 87,060,294 (-)Ensembl
Rnor_6.0 Ensembl288,384,796 - 88,414,012 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000097272   ⟹   ENSRNOP00000090014
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl287,025,598 - 87,060,204 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000107983   ⟹   ENSRNOP00000090462
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl287,032,067 - 87,060,204 (-)Ensembl
RefSeq Acc Id: NM_001100645   ⟹   NP_001094115
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8288,753,300 - 88,781,435 (-)NCBI
mRatBN7.2287,032,067 - 87,060,204 (-)NCBI
Rnor_6.0288,384,796 - 88,414,012 (-)NCBI
Rnor_5.02108,155,195 - 108,184,411 (-)NCBI
Celera282,622,863 - 82,823,739 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039101805   ⟹   XP_038957733
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8288,746,904 - 88,781,532 (-)NCBI
mRatBN7.2287,025,671 - 87,060,285 (-)NCBI
RefSeq Acc Id: XM_039101808   ⟹   XP_038957736
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8288,753,497 - 88,781,518 (-)NCBI
mRatBN7.2287,031,683 - 87,060,269 (-)NCBI
RefSeq Acc Id: XM_039101810   ⟹   XP_038957738
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8288,753,497 - 88,781,493 (-)NCBI
mRatBN7.2287,031,683 - 87,060,313 (-)NCBI
RefSeq Acc Id: XM_039101811   ⟹   XP_038957739
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8288,753,497 - 88,777,416 (-)NCBI
mRatBN7.2287,031,683 - 87,056,786 (-)NCBI
RefSeq Acc Id: XM_039101813   ⟹   XP_038957741
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8288,759,421 - 88,781,529 (-)NCBI
mRatBN7.2287,038,194 - 87,060,288 (-)NCBI
RefSeq Acc Id: XM_039101814   ⟹   XP_038957742
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8288,753,497 - 88,773,802 (-)NCBI
mRatBN7.2287,031,683 - 87,052,578 (-)NCBI
RefSeq Acc Id: XM_039101815   ⟹   XP_038957743
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8288,766,115 - 88,781,522 (-)NCBI
mRatBN7.2287,044,883 - 87,060,287 (-)NCBI
RefSeq Acc Id: NP_001094115   ⟸   NM_001100645
- UniProtKB: A0A8I6ADQ1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000014762   ⟸   ENSRNOT00000014762
RefSeq Acc Id: XP_038957733   ⟸   XM_039101805
- Peptide Label: isoform X2
- UniProtKB: A0A8I6AM64 (UniProtKB/TrEMBL),   A0A8I6ADQ1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038957738   ⟸   XM_039101810
- Peptide Label: isoform X1
- UniProtKB: E9PTY0 (UniProtKB/TrEMBL),   A0A8I6ADQ1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038957736   ⟸   XM_039101808
- Peptide Label: isoform X3
- UniProtKB: A0A8I6ADQ1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038957739   ⟸   XM_039101811
- Peptide Label: isoform X4
- UniProtKB: A6IH18 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038957742   ⟸   XM_039101814
- Peptide Label: isoform X6
- UniProtKB: A6IH18 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038957741   ⟸   XM_039101813
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038957743   ⟸   XM_039101815
- Peptide Label: isoform X7
RefSeq Acc Id: ENSRNOP00000090014   ⟸   ENSRNOT00000097272
RefSeq Acc Id: ENSRNOP00000090462   ⟸   ENSRNOT00000107983

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-E9PTY0-F1-model_v2 AlphaFold E9PTY0 1-1025 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13691226
Promoter ID:EPDNEW_R1749
Type:initiation region
Name:Lrrcc1_1
Description:leucine rich repeat and coiled-coil centrosomal protein 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0288,413,976 - 88,414,036EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:628722 AgrOrtholog
BioCyc Gene G2FUF-53802 BioCyc
Ensembl Genes ENSRNOG00000010891 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000014762.8 UniProtKB/TrEMBL
  ENSRNOT00000097272.1 UniProtKB/TrEMBL
  ENSRNOT00000107983.1 UniProtKB/TrEMBL
Gene3D-CATH 3.80.10.10 UniProtKB/TrEMBL
InterPro L_dom-like UniProtKB/TrEMBL
  Leu-rich_rpt UniProtKB/TrEMBL
  Leu-rich_rpt_4 UniProtKB/TrEMBL
NCBI Gene 266808 ENTREZGENE
PANTHER LEUCINE RICH REPEAT AND COILED-COIL CENTROSOMAL PROTEIN 1 UniProtKB/TrEMBL
  PROTEIN PHOSPHATASE 1 REGULATORY SUBUNIT SDS22-RELATED UniProtKB/TrEMBL
Pfam LRR_4 UniProtKB/TrEMBL
PhenoGen Lrrcc1 PhenoGen
PROSITE LRR UniProtKB/TrEMBL
RatGTEx ENSRNOG00000010891 RatGTEx
SMART LRR_SD22 UniProtKB/TrEMBL
Superfamily-SCOP L domain-like UniProtKB/TrEMBL
UniProt A0A8I6ADQ1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AM64 ENTREZGENE, UniProtKB/TrEMBL
  A6IH18 ENTREZGENE, UniProtKB/TrEMBL
  E9PTY0 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-05-24 Lrrcc1  leucine rich repeat and coiled-coil centrosomal protein 1  LOC686123  similar to leucine rich repeat and coiled-coil domain containing 1  Data merged from RGD:1585476 1643240 APPROVED
2012-10-05 Lrrcc1  leucine rich repeat and coiled-coil centrosomal protein 1  Lrrcc1  leucine rich repeat and coiled-coil domain containing 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-02-25 Lrrcc1  leucine rich repeat and coiled-coil domain containing 1  Sap2  sodium channel associated protein 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-01-09 LOC686123  similar to leucine rich repeat and coiled-coil domain containing 1  LOC678993  similar to leucine rich repeat and coiled-coil domain containing 1  Data merged from RGD:1594238 1643240 APPROVED
2006-11-20 LOC678993  similar to leucine rich repeat and coiled-coil domain containing 1      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-11-19 LOC686123  similar to leucine rich repeat and coiled-coil domain containing 1      Symbol and Name status set to provisional 70820 PROVISIONAL
2005-01-20 Sap2  sodium channel associated protein 2    sodium channel associated protein 2, Sap2  Name updated 1299863 APPROVED
2003-02-27 Sap2  sodium channel associated protein 2, Sap2      Symbol and Name status set to provisional 70820 PROVISIONAL