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Imported Disease Annotations - CTDObject Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Rnf34 | Rat | Colonic Neoplasms | | ISO | RNF34 (Homo sapiens) | 11554173 | CTD Direct Evidence: therapeutic | CTD | PMID:16270526 | |
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Imported Disease Annotations - CTDObject Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Rnf34 | Rat | Colonic Neoplasms | | ISO | RNF34 (Homo sapiens) | 11554173 | CTD Direct Evidence: therapeutic | CTD | PMID:16270526 | |
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# | Reference Title | Reference Citation |
1. | A palmitoylated RING finger ubiquitin ligase and its homologue in the brain membranes. | Araki K, etal., J Neurochem 2003 Aug;86(3):749-62. |
2. | Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. | Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27. |
3. | Ring finger protein 34 (RNF34) interacts with and promotes gamma-aminobutyric acid type-A receptor degradation via ubiquitination of the gamma2 subunit. | Jin H, etal., J Biol Chem. 2014 Oct 17;289(42):29420-36. doi: 10.1074/jbc.M114.603068. Epub 2014 Sep 5. |
4. | GOA pipeline | RGD automated data pipeline |
5. | Data Import for Chemical-Gene Interactions | RGD automated import pipeline for gene-chemical interactions |
6. | Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. | Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11. |
PMID:15069192 | PMID:15489334 | PMID:17121812 | PMID:18382127 | PMID:22064484 | PMID:25012219 | PMID:28902127 |
Rnf34 (Rattus norvegicus - Norway rat) |
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RNF34 (Homo sapiens - human) |
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Rnf34 (Mus musculus - house mouse) |
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Rnf34 (Chinchilla lanigera - long-tailed chinchilla) |
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RNF34 (Pan paniscus - bonobo/pygmy chimpanzee) |
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RNF34 (Canis lupus familiaris - dog) |
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Rnf34 (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
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RNF34 (Sus scrofa - pig) |
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RNF34 (Chlorocebus sabaeus - green monkey) |
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Rnf34 (Heterocephalus glaber - naked mole-rat) |
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Variants in Rnf34
173 total Variants ![]() |
The detailed report is available here: | ![]() | Full Report | ![]() | CSV | ![]() | TAB | ![]() | Printer |
miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/). For more information about miRGate, see PMID:25858286 or access the full paper here. |
The following QTLs overlap with this region. | ![]() | Full Report | ![]() | CSV | ![]() | TAB | ![]() | Printer | ![]() | Gviewer |
RH128319 |
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alimentary part of gastrointestinal system
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appendage
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circulatory system
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ectoderm
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endocrine system
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endoderm
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exocrine system
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hemolymphoid system
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hepatobiliary system
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integumental system
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mesenchyme
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mesoderm
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nervous system
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renal system
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reproductive system
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respiratory system
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9 | 11 | 49 | 113 | 91 | 90 | 59 | 25 | 59 | 6 | 218 | 97 | 93 | 45 | 60 | 31 |
Ensembl Acc Id: | ENSRNOT00000001799 ⟹ ENSRNOP00000001799 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
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Ensembl Acc Id: | ENSRNOT00000103449 ⟹ ENSRNOP00000080689 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | NM_001004075 ⟹ NP_001004075 | ||||||||||||||||||||||||||||
RefSeq Status: | PROVISIONAL | ||||||||||||||||||||||||||||
Type: | CODING | ||||||||||||||||||||||||||||
Position: |
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Sequence: |
RefSeq Acc Id: | XM_006249360 ⟹ XP_006249422 | ||||||||||||||||||||
Type: | CODING | ||||||||||||||||||||
Position: |
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Sequence: |
RefSeq Acc Id: | XM_006249361 ⟹ XP_006249423 | ||||||||||||||||||||
Type: | CODING | ||||||||||||||||||||
Position: |
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Sequence: |
RefSeq Acc Id: | XM_063271103 ⟹ XP_063127173 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | XM_063271104 ⟹ XP_063127174 | ||||||||
Type: | CODING | ||||||||
Position: |
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RefSeq Acc Id: | NP_001004075 ⟸ NM_001004075 |
- UniProtKB: | Q8CIP0 (UniProtKB/Swiss-Prot), Q6AYH3 (UniProtKB/Swiss-Prot), A6J174 (UniProtKB/TrEMBL) |
- Sequence: |
RefSeq Acc Id: | XP_006249423 ⟸ XM_006249361 |
- Peptide Label: | isoform X2 |
- Sequence: |
RefSeq Acc Id: | XP_006249422 ⟸ XM_006249360 |
- Peptide Label: | isoform X1 |
- UniProtKB: | A0A8I6G4W4 (UniProtKB/TrEMBL) |
- Sequence: |
Ensembl Acc Id: | ENSRNOP00000001799 ⟸ ENSRNOT00000001799 |
Ensembl Acc Id: | ENSRNOP00000080689 ⟸ ENSRNOT00000103449 |
RefSeq Acc Id: | XP_063127174 ⟸ XM_063271104 |
- Peptide Label: | isoform X1 |
- UniProtKB: | A0A8I6G4W4 (UniProtKB/TrEMBL) |
RefSeq Acc Id: | XP_063127173 ⟸ XM_063271103 |
- Peptide Label: | isoform X1 |
- UniProtKB: | A0A8I6G4W4 (UniProtKB/TrEMBL) |
Name | Modeler | Protein Id | AA Range | Protein Structure |
AF-Q6AYH3-F1-model_v2 | AlphaFold | Q6AYH3 | 1-381 | view protein structure |
eQTL | View at Phenogen | |
WGCNA | View at Phenogen | |
Tissue/Strain Expression | View at Phenogen |
RGD ID: | 13698638 | ||||||||
Promoter ID: | EPDNEW_R9161 | ||||||||
Type: | initiation region | ||||||||
Name: | Rnf34_1 | ||||||||
Description: | ring finger protein 34 | ||||||||
SO ACC ID: | SO:0000170 | ||||||||
Source: | EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/) | ||||||||
Experiment Methods: | Single-end sequencing. | ||||||||
Position: |
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Database | Acc Id | Source(s) |
AGR Gene | RGD:628636 | AgrOrtholog |
BioCyc Gene | G2FUF-19277 | BioCyc |
Ensembl Genes | ENSRNOG00000001331 | Ensembl, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
Ensembl Transcript | ENSRNOT00000001799.6 | UniProtKB/Swiss-Prot |
ENSRNOT00000103449.1 | UniProtKB/TrEMBL | |
Gene3D-CATH | 1.10.720.140 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
1.10.720.30 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
3.30.40.10 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
IMAGE_CLONE | IMAGE:7115027 | IMAGE-MGC_LOAD |
InterPro | CARP1_2_FYVE | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
CARP1_FYVE | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
RING-FYVE_E3_ubiquitin-ligase | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
RNF34L-like_HeH | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
SAP_dom_sf | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
Znf_FYVE_PHD | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
Znf_RING | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
Znf_RING/FYVE/PHD | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
KEGG Report | rno:282845 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
MGC_CLONE | MGC:93980 | IMAGE-MGC_LOAD |
NCBI Gene | 282845 | ENTREZGENE |
PANTHER | CASPASE REGULATOR, RING FINGER DOMAIN-CONTAINING | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
E3 UBIQUITIN-PROTEIN LIGASE RNF34 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
Pfam | FYVE_CARP1-2 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
RNF34L-like_3rd | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
zf-C3HC4_3 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
PhenoGen | Rnf34 | PhenoGen |
PROSITE | ZF_RING_2 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
RatGTEx | ENSRNOG00000001331 | RatGTEx |
SMART | RING | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
Superfamily-SCOP | RING/U-box | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
SSF57903 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
SSF68906 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
UniProt | A0A8I6G4W4 | ENTREZGENE, UniProtKB/TrEMBL |
A6J174 | ENTREZGENE, UniProtKB/TrEMBL | |
Q6AYH3 | ENTREZGENE | |
Q8CIP0 | ENTREZGENE | |
RNF34_RAT | UniProtKB/Swiss-Prot | |
UniProt Secondary | Q8CIP0 | UniProtKB/Swiss-Prot |
Date | Current Symbol | Current Name | Previous Symbol | Previous Name | Description | Reference | Status |
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2016-03-16 | Rnf34 | ring finger protein 34 | Rnf34 | ring finger protein 34, E3 ubiquitin protein ligase | Nomenclature updated to reflect human and mouse nomenclature | 1299863 | APPROVED |
2012-10-15 | Rnf34 | ring finger protein 34, E3 ubiquitin protein ligase | Rnf34 | ring finger protein 34 | Nomenclature updated to reflect human and mouse nomenclature | 1299863 | APPROVED |
2004-09-10 | Rnf34 | ring finger protein 34 | Symbol and Name status set to approved | 1299863 | APPROVED | ||
2003-02-27 | Rnf34 | ring finger protein 34 | Symbol and Name status set to provisional | 70820 | PROVISIONAL |
Note Type | Note | Reference |
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gene_domains | contains two zinc finger motifs and a RING finger domain | 708308 |
gene_expression | expressed in brain | 708308 |