Ltbp3 (latent transforming growth factor beta binding protein 3) - Rat Genome Database

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Gene: Ltbp3 (latent transforming growth factor beta binding protein 3) Mus musculus
Analyze
Symbol: Ltbp3
Name: latent transforming growth factor beta binding protein 3
RGD ID: 62349
MGI Page MGI
Description: Predicted to enable transforming growth factor beta binding activity. Acts upstream of or within several processes, including negative regulation of chondrocyte differentiation; positive regulation of bone resorption; and transforming growth factor beta receptor signaling pathway. Located in extracellular region. Is expressed in several structures, including cardiovascular system; central nervous system; jaw; limb; and respiratory system. Used to study brachyolmia-amelogenesis imperfecta syndrome. Human ortholog(s) of this gene implicated in brachyolmia-amelogenesis imperfecta syndrome and geleophysic dysplasia 3. Orthologous to human LTBP3 (latent transforming growth factor beta binding protein 3).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: latent-transforming growth factor beta-binding protein 3; Ltb; LTBP-3; Ltbp2; mFLJ00070
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
NCBI Annotation Information: Note: This gene (GeneID: 16998) was identified as Ltbp2 in PMID: 7719025. The official symbol for this gene is Ltbp3. [27 Jan 2017]
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39195,790,928 - 5,808,564 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl195,790,932 - 5,808,560 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38195,740,900 - 5,758,536 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl195,740,904 - 5,758,532 (+)Ensemblmm10GRCm38
MGSCv37195,740,904 - 5,758,532 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36195,742,127 - 5,758,525 (+)NCBIMGSCv36mm8
Celera195,610,947 - 5,628,578 (+)NCBICelera
Cytogenetic Map19ANCBI
cM Map194.34NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal basicranium morphology  (IAGP)
abnormal basioccipital bone morphology  (IAGP)
abnormal basisphenoid bone morphology  (IAGP)
abnormal bone remodeling  (IAGP)
abnormal cervical vertebrae morphology  (IAGP)
abnormal craniofacial bone morphology  (IAGP)
abnormal craniofacial morphology  (IEA)
abnormal cranium morphology  (IAGP)
abnormal enamel morphology  (IAGP)
abnormal enamel organ morphology  (IAGP)
abnormal eye morphology  (IEA)
abnormal foramen magnum morphology  (IAGP)
abnormal frontal bone morphology  (IAGP)
abnormal joint morphology  (IAGP)
abnormal kidney morphology  (IEA)
abnormal long bone epiphyseal plate proliferative zone  (IAGP)
abnormal long bone metaphysis morphology  (IAGP)
abnormal mandible morphology  (IEA)
abnormal maxilla morphology  (IEA)
abnormal neurocranium morphology  (IAGP)
abnormal nose morphology  (IEA)
abnormal skin morphology  (IEA)
abnormal spine curvature  (IEA)
abnormal spleen morphology  (IEA)
abnormal synchondrosis  (IEA)
abnormal thoracic cage shape  (IAGP)
abnormal thoracic vertebrae morphology  (IAGP)
abnormal tooth color  (IEA)
abnormal tooth morphology  (IEA)
abnormal trabecular bone morphology  (IAGP)
abnormal zygomatic bone morphology  (IEA)
decreased body size  (IEA)
decreased body weight  (IAGP)
decreased grip strength  (IEA)
decreased length of long bones  (IAGP)
decreased prepulse inhibition  (IEA)
decreased respiratory quotient  (IEA)
domed cranium  (IAGP)
ectopic cranial bone  (IAGP)
excessive tearing  (IEA)
hindlimb paralysis  (IEA)
increased grip strength  (IEA)
increased trabecular bone mass  (IAGP)
increased width of hypertrophic chondrocyte zone  (IAGP)
iris coloboma  (IEA)
kyphosis  (IAGP)
malocclusion  (IAGP)
misaligned incisors  (IAGP)
occipital bossing  (IAGP)
ocular hypertelorism  (IEA)
osteoarthritis  (IAGP)
osteosclerosis  (IAGP)
polycystic kidney  (IEA)
postnatal growth retardation  (IAGP)
premature bone ossification  (IAGP)
preweaning lethality, incomplete penetrance  (IEA)
prognathia  (IAGP)
reduced enamel thickness  (IAGP)
round head  (IAGP)
round orbits  (IEA)
short basicranium  (IAGP)
short face  (IEA)
short maxilla  (IAGP)
short snout  (IAGP)
short tibia  (IEA)
References

References - curated
# Reference Title Reference Citation
1. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
2. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
3. MGDs mouse GO annotations MGD data from the GO Consortium
4. MGD IEA MGD IEA
5. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
6. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
7. Mouse MP Annotation Import Pipeline RGD automated import pipeline
8. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:7716544   PMID:7719025   PMID:7730318   PMID:8589516   PMID:9008713   PMID:9027487   PMID:9501310   PMID:9571174   PMID:9602168   PMID:9730611   PMID:9763662   PMID:10349636  
PMID:10725249   PMID:10743502   PMID:11042159   PMID:11076861   PMID:11104663   PMID:11790802   PMID:12062452   PMID:12379497   PMID:12477932   PMID:12811825   PMID:15449545   PMID:15611103  
PMID:15782199   PMID:15878314   PMID:16049328   PMID:16049329   PMID:16141072   PMID:16141073   PMID:16537572   PMID:17804598   PMID:18287559   PMID:20436479   PMID:20530870   PMID:20945348  
PMID:21267068   PMID:21700711   PMID:21873635   PMID:22008794   PMID:23863478   PMID:25669657   PMID:26494287   PMID:26816005   PMID:28084688   PMID:29625025   PMID:30306291   PMID:30550785  
PMID:32325033   PMID:34321999   PMID:35933071  


Genomics

Comparative Map Data
Ltbp3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39195,790,928 - 5,808,564 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl195,790,932 - 5,808,560 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38195,740,900 - 5,758,536 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl195,740,904 - 5,758,532 (+)Ensemblmm10GRCm38
MGSCv37195,740,904 - 5,758,532 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36195,742,127 - 5,758,525 (+)NCBIMGSCv36mm8
Celera195,610,947 - 5,628,578 (+)NCBICelera
Cytogenetic Map19ANCBI
cM Map194.34NCBI
LTBP3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381165,538,559 - 65,558,359 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1165,538,559 - 65,558,930 (-)Ensemblhg38GRCh38
GRCh371165,306,030 - 65,325,830 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361165,062,850 - 65,082,006 (-)NCBIBuild 36Build 36hg18NCBI36
Build 341165,062,851 - 65,082,006NCBI
Celera1162,632,308 - 62,652,081 (-)NCBICelera
Cytogenetic Map11q13.1NCBI
HuRef1161,633,038 - 61,652,692 (-)NCBIHuRef
CHM1_11165,189,927 - 65,209,594 (-)NCBICHM1_1
T2T-CHM13v2.01165,532,759 - 65,552,582 (-)NCBIT2T-CHM13v2.0
Ltbp3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81212,458,362 - 212,475,302 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1212,459,185 - 212,475,302 (+)EnsemblGRCr8
mRatBN7.21203,029,412 - 203,045,975 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1203,029,877 - 203,045,975 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1211,382,686 - 211,398,784 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01218,475,275 - 218,491,375 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01211,166,319 - 211,182,420 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01221,099,155 - 221,116,096 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1221,099,998 - 221,116,096 (+)Ensemblrn6Rnor6.0
Rnor_5.01228,032,118 - 228,049,059 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41208,369,474 - 208,385,572 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1200,565,425 - 200,581,523 (+)NCBICelera
RGSC_v3.11208,528,203 - 208,529,495 (+)NCBI
Cytogenetic Map1q43NCBI
Ltbp3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542219,714,627 - 19,729,855 (+)Ensembl
ChiLan1.0NW_00495542219,714,161 - 19,730,344 (+)NCBIChiLan1.0ChiLan1.0
LTBP3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2966,768,503 - 66,788,309 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11167,811,243 - 67,831,116 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01160,897,897 - 60,917,690 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11164,233,504 - 64,252,797 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1164,233,504 - 64,252,802 (-)EnsemblpanPan2panpan1.1
LTBP3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11851,653,783 - 51,667,793 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1851,659,098 - 51,667,433 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1850,258,570 - 50,276,031 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01852,687,327 - 52,704,788 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1852,686,940 - 52,704,772 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11851,787,223 - 51,804,683 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01851,361,491 - 51,378,941 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01852,151,640 - 52,169,092 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Ltbp3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049477,460,548 - 7,476,122 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365993,902,897 - 3,918,471 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365993,902,903 - 3,918,471 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LTBP3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl26,701,510 - 6,720,153 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.126,701,455 - 6,720,191 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.225,843,784 - 5,861,806 (-)NCBISscrofa10.2Sscrofa10.2susScr3
LTBP3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.118,681,140 - 8,700,721 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl18,681,156 - 8,703,740 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666038105,977,192 - 105,998,405 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ltbp3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476720,845,949 - 20,860,673 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462476720,845,949 - 20,861,169 (+)NCBIHetGla 1.0HetGla 1.0hetGla2

Variants

.
Variants in Ltbp3
492 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:215
Count of miRNA genes:166
Interacting mature miRNAs:196
Transcripts:ENSMUST00000081496
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4142302Nstr1_mnerve sheath tumor resistance QTL 1 (mouse)Not determined19122371338Mouse
1301271Datd_mdopamine transporter density (mouse)Not determined19132340234Mouse
1300923Bits4_mbitterness sensitivity 4 (mouse)Not determined19332321637323348Mouse
11039522Tbbr4_mTrypanosoma brucei brucei response 4 (mouse)19531332639313470Mouse
25394536Skmw86_mskeletal muscle weight 86, TA (mouse)1950648178957825Mouse
4142161Drinksac2_mdrink saccharin 2 (mouse)Not determined120695286Mouse
1357819Tgct2_mtesticular germ cell tumor 2 (mouse)Not determined19332855120539663Mouse
4142406Pbctlp1_mperipheral blood cytotoxic T lymphocyte percentage 1 (mouse)Not determined132875174Mouse
1301800Faq10_mfluctuating asymmetry QTL 10 (mouse)Not determined19332321637323348Mouse
1300776Lfp3_mlong free running period 3 (mouse)Not determined19120328703Mouse
1300904Chab5_mcholesterol absorption 5 (mouse)Not determined19165376435653927Mouse
26884385Skwq14_mskull length QTL 14, 16 week (mouse)19325000035877400Mouse
1300591Pas3_mpulmonary adenoma susceptibility 3 (mouse)Not determined19332321637323348Mouse
1302126Skull26_mskull morphology 26 (mouse)Not determined19332321637323348Mouse

Markers in Region
RH127141  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38195,758,450 - 5,758,662UniSTSGRCm38
MGSCv37195,758,450 - 5,758,662UniSTSGRCm37
Celera195,628,496 - 5,628,708UniSTS
Cytogenetic Map19AUniSTS
Cytogenetic Map19BUniSTS
cM Map196.0UniSTS
cM Map192.0UniSTS
Whitehead/MRC_RH1936.43UniSTS
L40459  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38195,758,222 - 5,758,333UniSTSGRCm38
MGSCv37195,758,222 - 5,758,333UniSTSGRCm37
Celera195,628,268 - 5,628,379UniSTS
Cytogenetic Map19AUniSTS
Cytogenetic Map19BUniSTS
cM Map192.0UniSTS
cM Map196.0UniSTS
Whitehead/MRC_RH1957.17UniSTS
Whitehead/MRC_RH1954.28UniSTS
RH142164  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38195,758,462 - 5,758,654UniSTSGRCm38
GRCm381197,229,433 - 97,229,612UniSTSGRCm38
MGSCv37195,758,462 - 5,758,654UniSTSGRCm37
MGSCv371197,090,747 - 97,090,926UniSTSGRCm37
Celera195,628,508 - 5,628,700UniSTS
Celera11106,882,392 - 106,882,571UniSTS
Cytogenetic Map11DUniSTS
Cytogenetic Map19AUniSTS
Cytogenetic Map19BUniSTS
cM Map1156.0UniSTS
cM Map196.0UniSTS
cM Map192.0UniSTS
RH143828  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38195,741,617 - 5,741,771UniSTSGRCm38
MGSCv37195,741,617 - 5,741,771UniSTSGRCm37
Celera195,611,661 - 5,611,815UniSTS
Cytogenetic Map19A-BUniSTS
Cytogenetic Map19BUniSTS
cM Map192.0UniSTS
Ltbp3  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38195,756,583 - 5,757,763UniSTSGRCm38
MGSCv37195,756,583 - 5,757,763UniSTSGRCm37
Celera195,626,627 - 5,627,809UniSTS
Cytogenetic Map19BUniSTS
cM Map192.0UniSTS
Ltbp3  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38195,745,630 - 5,746,359UniSTSGRCm38
MGSCv37195,745,630 - 5,746,359UniSTSGRCm37
Celera195,615,674 - 5,616,403UniSTS
Cytogenetic Map19BUniSTS
cM Map192.0UniSTS
Ltbp3  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38195,758,143 - 5,758,526UniSTSGRCm38
MGSCv37195,758,143 - 5,758,526UniSTSGRCm37
Celera195,628,189 - 5,628,572UniSTS
Cytogenetic Map19AUniSTS
Cytogenetic Map19BUniSTS
cM Map192.0UniSTS


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_008520 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006531668 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006531669 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006531670 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006531671 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006531672 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006531673 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017318071 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017318072 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017318073 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036161454 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC134563 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK007774 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK038587 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK080869 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK131126 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK178255 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK183672 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK190895 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK201743 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC040761 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC054420 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC127051 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466612 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CJ179209 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L40459 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000081496   ⟹   ENSMUSP00000080214
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl195,790,932 - 5,808,560 (+)Ensembl
GRCm38.p6 Ensembl195,740,904 - 5,758,532 (+)Ensembl
Ensembl Acc Id: ENSMUST00000235336
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl195,805,090 - 5,808,560 (+)Ensembl
GRCm38.p6 Ensembl195,755,062 - 5,758,532 (+)Ensembl
Ensembl Acc Id: ENSMUST00000235898
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl195,792,385 - 5,795,911 (+)Ensembl
GRCm38.p6 Ensembl195,742,357 - 5,745,883 (+)Ensembl
Ensembl Acc Id: ENSMUST00000236130   ⟹   ENSMUSP00000158570
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl195,805,644 - 5,808,261 (+)Ensembl
GRCm38.p6 Ensembl195,755,616 - 5,758,233 (+)Ensembl
Ensembl Acc Id: ENSMUST00000236258
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl195,792,487 - 5,802,478 (+)Ensembl
GRCm38.p6 Ensembl195,742,459 - 5,752,450 (+)Ensembl
Ensembl Acc Id: ENSMUST00000236529   ⟹   ENSMUSP00000157845
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl195,806,822 - 5,807,804 (+)Ensembl
GRCm38.p6 Ensembl195,756,794 - 5,757,776 (+)Ensembl
Ensembl Acc Id: ENSMUST00000236617   ⟹   ENSMUSP00000158261
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl195,795,761 - 5,796,731 (+)Ensembl
GRCm38.p6 Ensembl195,745,733 - 5,746,703 (+)Ensembl
Ensembl Acc Id: ENSMUST00000237128
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl195,800,679 - 5,801,273 (+)Ensembl
GRCm38.p6 Ensembl195,750,651 - 5,751,245 (+)Ensembl
Ensembl Acc Id: ENSMUST00000237180
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl195,807,560 - 5,807,798 (+)Ensembl
GRCm38.p6 Ensembl195,757,532 - 5,757,770 (+)Ensembl
Ensembl Acc Id: ENSMUST00000237280
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl195,793,931 - 5,808,559 (+)Ensembl
GRCm38.p6 Ensembl195,743,903 - 5,758,531 (+)Ensembl
Ensembl Acc Id: ENSMUST00000237317
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl195,790,932 - 5,804,358 (+)Ensembl
GRCm38.p6 Ensembl195,740,904 - 5,754,330 (+)Ensembl
Ensembl Acc Id: ENSMUST00000237327
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl195,806,998 - 5,807,858 (+)Ensembl
GRCm38.p6 Ensembl195,756,970 - 5,757,830 (+)Ensembl
RefSeq Acc Id: NM_008520   ⟹   NP_032546
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39195,790,928 - 5,808,560 (+)NCBI
GRCm38195,740,900 - 5,758,532 (+)NCBI
MGSCv37195,740,904 - 5,758,532 (+)RGD
Celera195,610,947 - 5,628,578 (+)RGD
cM Map19 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006531668   ⟹   XP_006531731
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39195,791,226 - 5,808,564 (+)NCBI
GRCm38195,741,847 - 5,758,536 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006531669   ⟹   XP_006531732
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39195,791,226 - 5,808,564 (+)NCBI
GRCm38195,741,847 - 5,758,536 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006531670   ⟹   XP_006531733
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39195,791,226 - 5,808,564 (+)NCBI
GRCm38195,741,847 - 5,758,536 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006531671   ⟹   XP_006531734
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39195,791,226 - 5,808,564 (+)NCBI
GRCm38195,741,847 - 5,758,536 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006531672   ⟹   XP_006531735
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39195,791,226 - 5,808,564 (+)NCBI
GRCm38195,741,847 - 5,758,536 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006531673   ⟹   XP_006531736
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39195,792,385 - 5,808,564 (+)NCBI
GRCm38195,741,847 - 5,758,536 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017318071   ⟹   XP_017173560
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39195,791,226 - 5,808,564 (+)NCBI
GRCm38195,741,847 - 5,758,536 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017318072   ⟹   XP_017173561
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39195,791,226 - 5,808,564 (+)NCBI
GRCm38195,741,847 - 5,758,536 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017318073   ⟹   XP_017173562
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39195,791,226 - 5,808,564 (+)NCBI
GRCm38195,741,847 - 5,758,536 (+)NCBI
Sequence:
RefSeq Acc Id: XM_036161454   ⟹   XP_036017347
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39195,791,226 - 5,808,564 (+)NCBI
Sequence:
RefSeq Acc Id: NP_032546   ⟸   NM_008520
- Peptide Label: precursor
- UniProtKB: Q8BNQ6 (UniProtKB/Swiss-Prot),   Q61810 (UniProtKB/Swiss-Prot),   F8VQ06 (UniProtKB/TrEMBL),   Q6KAT1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006531734   ⟸   XM_006531671
- Peptide Label: isoform X4
- UniProtKB: Q6KAT1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006531735   ⟸   XM_006531672
- Peptide Label: isoform X6
- UniProtKB: Q6KAT1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006531732   ⟸   XM_006531669
- Peptide Label: isoform X2
- UniProtKB: Q6KAT1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006531733   ⟸   XM_006531670
- Peptide Label: isoform X3
- UniProtKB: Q6KAT1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006531731   ⟸   XM_006531668
- Peptide Label: isoform X1
- UniProtKB: Q6KAT1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006531736   ⟸   XM_006531673
- Peptide Label: isoform X9
- UniProtKB: Q6KAT1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017173560   ⟸   XM_017318071
- Peptide Label: isoform X7
- UniProtKB: Q6KAT1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017173561   ⟸   XM_017318072
- Peptide Label: isoform X8
- UniProtKB: Q6KAT1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017173562   ⟸   XM_017318073
- Peptide Label: isoform X10
- Sequence:
Ensembl Acc Id: ENSMUSP00000158261   ⟸   ENSMUST00000236617
Ensembl Acc Id: ENSMUSP00000157845   ⟸   ENSMUST00000236529
Ensembl Acc Id: ENSMUSP00000158570   ⟸   ENSMUST00000236130
Ensembl Acc Id: ENSMUSP00000080214   ⟸   ENSMUST00000081496
RefSeq Acc Id: XP_036017347   ⟸   XM_036161454
- Peptide Label: isoform X5
- UniProtKB: Q61810 (UniProtKB/Swiss-Prot),   F8VQ06 (UniProtKB/Swiss-Prot),   Q8BNQ6 (UniProtKB/Swiss-Prot),   Q6KAT1 (UniProtKB/TrEMBL)
Protein Domains
EGF-like   TB

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q61810-F1-model_v2 AlphaFold Q61810 1-1253 view protein structure

Promoters
RGD ID:6830201
Promoter ID:MM_KWN:26113
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6
Transcripts:AK135161_GM10815,   ENSMUST00000099954,   NM_008520,   UC008GFE.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36195,740,501 - 5,741,022 (+)MPROMDB
RGD ID:13678578
Promoter ID:EPDNEW_M23438
Type:initiation region
Name:Ltbp3_2
Description:Mus musculus latent transforming growth factor beta binding protein3 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M23439  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38195,740,900 - 5,740,960EPDNEW
RGD ID:6830172
Promoter ID:MM_KWN:26114
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   Brain,   Lung,   MEF_B4,   MEF_B6
Transcripts:ENSMUST00000076366
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36195,741,376 - 5,742,527 (+)MPROMDB
RGD ID:13678580
Promoter ID:EPDNEW_M23439
Type:initiation region
Name:Ltbp3_1
Description:Mus musculus latent transforming growth factor beta binding protein3 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_M23438  
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38195,742,027 - 5,742,087EPDNEW
RGD ID:6830194
Promoter ID:MM_KWN:26115
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:MEF_B4,   MEF_B6
Transcripts:UC008GFG.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36195,743,491 - 5,743,991 (+)MPROMDB
RGD ID:6847565
Promoter ID:MM_ACW:25873
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_4Hour,   Brain,   Kidney,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:LTBP3.JSEP07-UNSPLICED
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36195,757,296 - 5,758,487 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1101355 AgrOrtholog
Ensembl Genes ENSMUSG00000024940 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000081496 ENTREZGENE
  ENSMUST00000081496.6 UniProtKB/Swiss-Prot
Gene3D-CATH 3.90.290.10 UniProtKB/Swiss-Prot
  Laminin UniProtKB/Swiss-Prot
InterPro ECM_structural_protein UniProtKB/Swiss-Prot
  EGF-like_Ca-bd_dom UniProtKB/Swiss-Prot
  EGF-like_CS UniProtKB/Swiss-Prot
  EGF-like_dom UniProtKB/Swiss-Prot
  EGF-type_Asp/Asn_hydroxyl_site UniProtKB/Swiss-Prot
  EGF_Ca-bd_CS UniProtKB/Swiss-Prot
  Growth_fac_rcpt_cys_sf UniProtKB/Swiss-Prot
  NOTCH1_EGF-like UniProtKB/Swiss-Prot
  TB_dom UniProtKB/Swiss-Prot
  TB_dom_sf UniProtKB/Swiss-Prot
KEGG Report mmu:16998 UniProtKB/Swiss-Prot
MGD MGI:1101355 ENTREZGENE
NCBI Gene 16998 ENTREZGENE
PANTHER EGF-LIKE DOMAIN-CONTAINING PROTEIN UniProtKB/Swiss-Prot
  EGF-LIKE DOMAIN-CONTAINING PROTEIN UniProtKB/Swiss-Prot
Pfam EGF_CA UniProtKB/Swiss-Prot
  hEGF UniProtKB/Swiss-Prot
  PF00683 UniProtKB/Swiss-Prot
PhenoGen Ltbp3 PhenoGen
PROSITE ASX_HYDROXYL UniProtKB/Swiss-Prot
  EGF_1 UniProtKB/Swiss-Prot
  EGF_2 UniProtKB/Swiss-Prot
  EGF_3 UniProtKB/Swiss-Prot
  EGF_CA UniProtKB/Swiss-Prot
  PS51364 UniProtKB/Swiss-Prot
SMART EGF UniProtKB/Swiss-Prot
  EGF_CA UniProtKB/Swiss-Prot
Superfamily-SCOP EGF/Laminin UniProtKB/Swiss-Prot
  SSF57184 UniProtKB/Swiss-Prot
  SSF57581 UniProtKB/Swiss-Prot
UniProt A0A494BA04_MOUSE UniProtKB/TrEMBL
  A0A494BAW3_MOUSE UniProtKB/TrEMBL
  A0A494BBP4_MOUSE UniProtKB/TrEMBL
  F8VQ06 ENTREZGENE
  LTBP3_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q6KAT1 ENTREZGENE, UniProtKB/TrEMBL
  Q8BNQ6 ENTREZGENE
  Q9CVK2_MOUSE UniProtKB/TrEMBL
UniProt Secondary F8VQ06 UniProtKB/Swiss-Prot
  Q8BNQ6 UniProtKB/Swiss-Prot