Nxf1 (nuclear RNA export factor 1) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Behavioral & Substance Use Disorder Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Nxf1 (nuclear RNA export factor 1) Mus musculus
Analyze
Symbol: Nxf1
Name: nuclear RNA export factor 1
RGD ID: 62306
MGI Page MGI
Description: Enables mRNA binding activity. Acts upstream of or within poly(A)+ mRNA export from nucleus. Located in nuclear inclusion body. Part of nuclear pore. Is expressed in several structures, including central nervous system; genitourinary system; liver; sensory organ; and spleen. Orthologous to human NXF1 (nuclear RNA export factor 1).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Mex 67 homolog; Mex 67 homolog (S. cerevisiae); Mex67; Mex67h-pending; modifier of vibrator 1; mRNA export factor TAP; Mvb; Mvb1; nuclear RNA export factor 1 homolog; T; Tap; tip associated protein; tip associating protein; tip-associated protein; tip-associating protein
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39198,734,467 - 8,748,274 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl198,734,437 - 8,748,286 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38198,757,103 - 8,770,910 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl198,757,073 - 8,770,922 (+)Ensemblmm10GRCm38
MGSCv37198,831,593 - 8,845,400 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36198,824,148 - 8,837,955 (+)NCBIMGSCv36mm8
Celera198,517,111 - 8,530,801 (+)NCBICelera
Cytogenetic Map19ANCBI
cM Map195.5NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
1,2-dimethylhydrazine  (EXP)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP)
2,4,6-tribromophenol  (ISO)
2,4-dinitrotoluene  (ISO)
2,6-dinitrotoluene  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
3H-1,2-dithiole-3-thione  (ISO)
4,4'-sulfonyldiphenol  (ISO)
6-propyl-2-thiouracil  (ISO)
acrolein  (ISO)
acrylamide  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
alpha-pinene  (ISO)
amitrole  (ISO)
ammonium chloride  (ISO)
aristolochic acid A  (ISO)
Aroclor 1254  (EXP)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (EXP)
benzatropine  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP,ISO)
Brodifacoum  (ISO)
cadmium atom  (EXP)
cadmium dichloride  (EXP,ISO)
caffeine  (ISO)
cannabidiol  (ISO)
carbon nanotube  (EXP)
CGP 52608  (ISO)
chloropicrin  (ISO)
chrysene  (EXP)
cisplatin  (ISO)
clofibrate  (EXP)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
Cuprizon  (ISO)
dexamethasone  (ISO)
Dibutyl phosphate  (ISO)
dicrotophos  (ISO)
dimethylarsinous acid  (ISO)
disulfiram  (ISO)
ethanol  (EXP)
flavonoids  (ISO)
flutamide  (ISO)
FR900359  (ISO)
fulvestrant  (ISO)
gentamycin  (ISO)
indometacin  (ISO)
ivermectin  (ISO)
lead(0)  (ISO)
leflunomide  (ISO)
Licochalcone B  (ISO)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
methimazole  (ISO)
methyl methanesulfonate  (ISO)
methylisothiazolinone  (ISO)
methylmercury chloride  (ISO)
N-nitrosodiethylamine  (ISO)
okadaic acid  (ISO)
ozone  (ISO)
paracetamol  (ISO)
paraquat  (EXP)
pirinixic acid  (ISO)
potassium chromate  (ISO)
raloxifene  (ISO)
rotenone  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenite  (ISO)
Soman  (ISO)
sulfadimethoxine  (ISO)
tetraphene  (EXP)
thapsigargin  (ISO)
thioacetamide  (ISO)
thiram  (ISO)
titanium dioxide  (EXP)
trichloroethene  (ISO)
trichostatin A  (ISO)
triphenyl phosphate  (ISO)
urethane  (ISO)
valproic acid  (ISO)
versicolorin A  (ISO)
vinclozolin  (ISO)
vorinostat  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function
mRNA binding  (IDA)
nucleic acid binding  (IEA)
protein binding  (IPI,ISO)
RNA binding  (IBA,IDA,IEA)

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. RNA export mediated by tap involves NXT1-dependent interactions with the nuclear pore complex. Levesque L, etal., J Biol Chem 2001 Nov 30;276(48):44953-62. Epub 2001 Sep 28.
2. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
3. MGDs mouse GO annotations MGD data from the GO Consortium
4. Postage for the messenger: designating routes for nuclear mRNA export. Natalizio BJ and Wente SR, Trends Cell Biol. 2013 Aug;23(8):365-73. doi: 10.1016/j.tcb.2013.03.006. Epub 2013 Apr 11.
5. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
6. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
7. Mouse MP Annotation Import Pipeline RGD automated import pipeline
8. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:9182797   PMID:10349636   PMID:10786854   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12093754   PMID:12477932   PMID:12520002   PMID:12904583   PMID:14517553  
PMID:15489334   PMID:15615787   PMID:15782199   PMID:15820316   PMID:16014633   PMID:16033648   PMID:16141072   PMID:16141073   PMID:16314397   PMID:16800626   PMID:17001072   PMID:17548835  
PMID:19436707   PMID:19586903   PMID:21267068   PMID:21725067   PMID:21873635   PMID:21966449   PMID:23665500   PMID:23675524   PMID:24457600   PMID:24478440   PMID:24597485   PMID:25835743  
PMID:26167872   PMID:26426291   PMID:27113764   PMID:27114368   PMID:28378742   PMID:30196744   PMID:31918596   PMID:32236527   PMID:32325033   PMID:32434143   PMID:36114006   PMID:36772830  


Genomics

Comparative Map Data
Nxf1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39198,734,467 - 8,748,274 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl198,734,437 - 8,748,286 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38198,757,103 - 8,770,910 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl198,757,073 - 8,770,922 (+)Ensemblmm10GRCm38
MGSCv37198,831,593 - 8,845,400 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36198,824,148 - 8,837,955 (+)NCBIMGSCv36mm8
Celera198,517,111 - 8,530,801 (+)NCBICelera
Cytogenetic Map19ANCBI
cM Map195.5NCBI
NXF1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381162,792,130 - 62,805,440 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1162,792,123 - 62,806,302 (-)Ensemblhg38GRCh38
GRCh371162,559,602 - 62,572,912 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361162,316,174 - 62,329,540 (-)NCBIBuild 36Build 36hg18NCBI36
Build 341162,316,219 - 62,329,529NCBI
Celera1159,888,182 - 59,901,548 (-)NCBICelera
Cytogenetic Map11q12.3NCBI
HuRef1158,888,624 - 58,901,991 (-)NCBIHuRef
CHM1_11162,442,680 - 62,456,046 (-)NCBICHM1_1
T2T-CHM13v2.01162,781,522 - 62,794,833 (-)NCBIT2T-CHM13v2.0
Nxf1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81215,084,563 - 215,097,756 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1215,084,099 - 215,097,756 (+)EnsemblGRCr8
mRatBN7.21205,655,442 - 205,668,637 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1205,655,375 - 205,668,636 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1214,062,638 - 214,077,055 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01221,098,997 - 221,112,188 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01213,791,700 - 213,804,891 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01224,957,535 - 224,970,728 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1224,957,517 - 224,970,727 (+)Ensemblrn6Rnor6.0
Rnor_5.01231,895,708 - 231,908,901 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41211,428,605 - 211,441,798 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1203,168,372 - 203,181,566 (+)NCBICelera
RGSC_v3.11211,587,034 - 211,600,227 (+)NCBI
Cytogenetic Map1q43NCBI
Nxf1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955599439,775 - 454,300 (+)Ensembl
ChiLan1.0NW_004955599439,773 - 450,834 (+)NCBIChiLan1.0ChiLan1.0
NXF1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2964,017,231 - 64,031,828 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11165,059,923 - 65,074,091 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01158,147,548 - 58,161,393 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11161,501,541 - 61,514,943 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1161,501,546 - 61,514,943 (-)EnsemblpanPan2panpan1.1
NXF1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11853,884,512 - 53,895,168 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1853,884,546 - 53,895,162 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1852,490,545 - 52,501,204 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01854,936,964 - 54,947,631 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1854,936,955 - 54,947,629 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11854,033,593 - 54,044,247 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01853,608,040 - 53,618,708 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01854,404,311 - 54,414,971 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Nxf1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494710,374,922 - 10,387,572 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936581488,718 - 504,853 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936581488,691 - 501,323 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NXF1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl28,969,581 - 8,981,984 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.128,968,659 - 8,983,276 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.228,315,196 - 8,327,226 (+)NCBISscrofa10.2Sscrofa10.2susScr3
NXF1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1111,096,289 - 11,111,186 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl111,096,323 - 11,111,632 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666038108,439,809 - 108,454,239 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Nxf1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249261,247,071 - 1,269,146 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046249261,247,940 - 1,268,968 (-)NCBIHetGla 1.0HetGla 1.0hetGla2

Variants

.
Variants in Nxf1
353 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:2521
Count of miRNA genes:811
Interacting mature miRNAs:1083
Transcripts:ENSMUST00000010241, ENSMUST00000183780, ENSMUST00000183898, ENSMUST00000183939, ENSMUST00000184387, ENSMUST00000184663, ENSMUST00000184756, ENSMUST00000184808, ENSMUST00000184826, ENSMUST00000184970, ENSMUST00000185056
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4142302Nstr1_mnerve sheath tumor resistance QTL 1 (mouse)Not determined19122371338Mouse
1301271Datd_mdopamine transporter density (mouse)Not determined19132340234Mouse
1300923Bits4_mbitterness sensitivity 4 (mouse)Not determined19332321637323348Mouse
11039522Tbbr4_mTrypanosoma brucei brucei response 4 (mouse)19531332639313470Mouse
25394536Skmw86_mskeletal muscle weight 86, TA (mouse)1950648178957825Mouse
4142161Drinksac2_mdrink saccharin 2 (mouse)Not determined120695286Mouse
1357819Tgct2_mtesticular germ cell tumor 2 (mouse)Not determined19332855120539663Mouse
4142406Pbctlp1_mperipheral blood cytotoxic T lymphocyte percentage 1 (mouse)Not determined132875174Mouse
1301800Faq10_mfluctuating asymmetry QTL 10 (mouse)Not determined19332321637323348Mouse
1300776Lfp3_mlong free running period 3 (mouse)Not determined19120328703Mouse
1300904Chab5_mcholesterol absorption 5 (mouse)Not determined19165376435653927Mouse
26884385Skwq14_mskull length QTL 14, 16 week (mouse)19325000035877400Mouse
1300591Pas3_mpulmonary adenoma susceptibility 3 (mouse)Not determined19332321637323348Mouse
1302126Skull26_mskull morphology 26 (mouse)Not determined19332321637323348Mouse

Markers in Region
RH127663  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38198,772,059 - 8,772,247UniSTSGRCm38
MGSCv37198,846,549 - 8,846,737UniSTSGRCm37
Celera198,531,950 - 8,532,138UniSTS
Cytogenetic Map19AUniSTS
cM Map195.0UniSTS
Nxf1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map19AUniSTS
cM Map195.0UniSTS
AV208457  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38198,756,626 - 8,756,725UniSTSGRCm38
MGSCv37198,831,116 - 8,831,215UniSTSGRCm37
Celera198,516,634 - 8,516,733UniSTS
Cytogenetic Map19AUniSTS
cM Map195.0UniSTS
Whitehead/MRC_RH1980.66UniSTS
AU014962  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38198,755,348 - 8,755,589UniSTSGRCm38
MGSCv37198,829,838 - 8,830,079UniSTSGRCm37
Celera198,515,356 - 8,515,597UniSTS
Cytogenetic Map19AUniSTS
cM Map19 UniSTS
Whitehead/MRC_RH1982.07UniSTS


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001276704 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_016813 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC025794 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF093140 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK052937 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK077644 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK079583 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK086527 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK088634 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK133883 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK143640 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK167518 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK184410 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK191466 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK194022 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK195941 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK197084 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK199824 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC005594 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466612 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  LXEJ02006816 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000010241   ⟹   ENSMUSP00000010241
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl198,734,437 - 8,748,286 (+)Ensembl
GRCm38.p6 Ensembl198,757,073 - 8,770,922 (+)Ensembl
Ensembl Acc Id: ENSMUST00000183780
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl198,734,483 - 8,744,977 (+)Ensembl
GRCm38.p6 Ensembl198,757,119 - 8,767,613 (+)Ensembl
Ensembl Acc Id: ENSMUST00000183898
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl198,747,456 - 8,748,285 (+)Ensembl
GRCm38.p6 Ensembl198,770,092 - 8,770,921 (+)Ensembl
Ensembl Acc Id: ENSMUST00000183939   ⟹   ENSMUSP00000139351
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl198,734,514 - 8,742,655 (+)Ensembl
GRCm38.p6 Ensembl198,757,150 - 8,765,291 (+)Ensembl
Ensembl Acc Id: ENSMUST00000184387
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl198,744,375 - 8,745,251 (+)Ensembl
GRCm38.p6 Ensembl198,767,011 - 8,767,887 (+)Ensembl
Ensembl Acc Id: ENSMUST00000184756   ⟹   ENSMUSP00000139050
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl198,734,514 - 8,741,103 (+)Ensembl
GRCm38.p6 Ensembl198,757,150 - 8,763,739 (+)Ensembl
Ensembl Acc Id: ENSMUST00000184808
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl198,747,500 - 8,748,226 (+)Ensembl
GRCm38.p6 Ensembl198,770,136 - 8,770,862 (+)Ensembl
Ensembl Acc Id: ENSMUST00000184826   ⟹   ENSMUSP00000139229
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl198,745,999 - 8,748,213 (+)Ensembl
GRCm38.p6 Ensembl198,768,635 - 8,770,849 (+)Ensembl
Ensembl Acc Id: ENSMUST00000184970   ⟹   ENSMUSP00000139124
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl198,734,471 - 8,748,271 (+)Ensembl
GRCm38.p6 Ensembl198,757,107 - 8,770,907 (+)Ensembl
Ensembl Acc Id: ENSMUST00000185056
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl198,744,041 - 8,746,531 (+)Ensembl
GRCm38.p6 Ensembl198,766,677 - 8,769,167 (+)Ensembl
RefSeq Acc Id: NM_001276704   ⟹   NP_001263633
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39198,734,481 - 8,748,274 (+)NCBI
GRCm38198,757,117 - 8,770,910 (+)NCBI
Celera198,517,111 - 8,530,801 (+)NCBI
Sequence:
RefSeq Acc Id: NM_016813   ⟹   NP_058093
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39198,734,467 - 8,748,274 (+)NCBI
GRCm38198,757,103 - 8,770,910 (+)ENTREZGENE
MGSCv37198,831,593 - 8,845,400 (+)RGD
Celera198,517,111 - 8,530,801 (+)RGD
cM Map19 ENTREZGENE
Sequence:
RefSeq Acc Id: NP_058093   ⟸   NM_016813
- Peptide Label: isoform 1
- UniProtKB: Q99JX7 (UniProtKB/Swiss-Prot),   Q3TJA5 (UniProtKB/Swiss-Prot),   O88985 (UniProtKB/Swiss-Prot),   Q8BP60 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001263633   ⟸   NM_001276704
- Peptide Label: isoform 2
- UniProtKB: V9GXF3 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSMUSP00000139229   ⟸   ENSMUST00000184826
Ensembl Acc Id: ENSMUSP00000139124   ⟸   ENSMUST00000184970
Ensembl Acc Id: ENSMUSP00000139050   ⟸   ENSMUST00000184756
Ensembl Acc Id: ENSMUSP00000139351   ⟸   ENSMUST00000183939
Ensembl Acc Id: ENSMUSP00000010241   ⟸   ENSMUST00000010241
Protein Domains
NTF2   Nuclear RNA export factor Tap RNA-binding   RRM   TAP-C

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q99JX7-F1-model_v2 AlphaFold Q99JX7 1-618 view protein structure

Promoters
RGD ID:13678806
Promoter ID:EPDNEW_M23552
Type:initiation region
Name:Nxf1_1
Description:Mus musculus nuclear RNA export factor 1 , transcript variant2, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38198,757,148 - 8,757,208EPDNEW
RGD ID:6830308
Promoter ID:MM_KWN:26304
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:AK043475_1700023D09RIK,   NM_016813,   UC008GMQ.1,   XM_001477573_GM2485
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36198,829,911 - 8,831,682 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1858330 AgrOrtholog
Ensembl Genes ENSMUSG00000010097 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000010241 ENTREZGENE
  ENSMUST00000010241.14 UniProtKB/Swiss-Prot
  ENSMUST00000184970 ENTREZGENE
Gene3D-CATH 3.10.450.50 UniProtKB/Swiss-Prot
  3.30.70.330 UniProtKB/Swiss-Prot
  3.80.10.10 UniProtKB/Swiss-Prot
  DNA helicase RuvA subunit, C-terminal domain UniProtKB/Swiss-Prot
InterPro Leu-rich_rpt UniProtKB/Swiss-Prot
  LRR_dom_sf UniProtKB/Swiss-Prot
  NTF2 UniProtKB/Swiss-Prot
  NTF2-like_dom_sf UniProtKB/Swiss-Prot
  Nuclear_transport_factor_2_euk UniProtKB/Swiss-Prot
  Nucleotide-bd_a/b_plait_sf UniProtKB/Swiss-Prot
  NXF_fam UniProtKB/Swiss-Prot
  RBD_domain_sf UniProtKB/Swiss-Prot
  TAP_C_dom UniProtKB/Swiss-Prot
  Tap_RNA-bd UniProtKB/Swiss-Prot
  UBA-like_sf UniProtKB/Swiss-Prot
KEGG Report mmu:53319 UniProtKB/Swiss-Prot
MGD MGI:1858330 ENTREZGENE
NCBI Gene Nxf1 ENTREZGENE
PANTHER NUCLEAR RNA EXPORT FACTOR 1 UniProtKB/Swiss-Prot
  PTHR10662 UniProtKB/Swiss-Prot
Pfam LRR_NXF1-5 UniProtKB/Swiss-Prot
  NXF_NTF2 UniProtKB/Swiss-Prot
  Tap-RNA_bind UniProtKB/Swiss-Prot
  TAP_C UniProtKB/Swiss-Prot
PhenoGen Nxf1 PhenoGen
PROSITE LRR UniProtKB/Swiss-Prot
  NTF2_DOMAIN UniProtKB/Swiss-Prot
  TAP_C UniProtKB/Swiss-Prot
SMART TAP_C UniProtKB/Swiss-Prot
Superfamily-SCOP L domain-like UniProtKB/Swiss-Prot
  SSF46934 UniProtKB/Swiss-Prot
  SSF54427 UniProtKB/Swiss-Prot
  SSF54928 UniProtKB/Swiss-Prot
UniProt NXF1_MOUSE UniProtKB/Swiss-Prot
  O88985 ENTREZGENE
  Q3TJA5 ENTREZGENE
  Q8BP60 ENTREZGENE, UniProtKB/TrEMBL
  Q99JX7 ENTREZGENE
  V9GX96_MOUSE UniProtKB/TrEMBL
  V9GXF3 ENTREZGENE, UniProtKB/TrEMBL
  V9GXM5_MOUSE UniProtKB/TrEMBL
  V9GXW3_MOUSE UniProtKB/TrEMBL
UniProt Secondary O88985 UniProtKB/Swiss-Prot
  Q3TJA5 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2024-08-21 Nxf1  nuclear RNA export factor 1  Mex67h-pending  Mex 67 homolog (S. cerevisiae)  Symbol and/or name change 5135510 APPROVED
2024-08-21 Mex67h-pending  Mex 67 homolog (S. cerevisiae)  Nxf1  nuclear RNA export factor 1  Symbol and/or name change 5135510 APPROVED
2012-06-26 Nxf1  nuclear RNA export factor 1  Nxf1  nuclear RNA export factor 1 homolog (S. cerevisiae)  Symbol and/or name change 5135510 APPROVED