Gpr88 (G-protein coupled receptor 88)

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Gene: Gpr88 (G-protein coupled receptor 88) Mus musculus

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Symbol:

Gpr88

Name:

G-protein coupled receptor 88

RGD ID:

62214

MGI Page

MGI

Description:

Enables cytoskeletal motor activity. Involved in motor learning. Acts upstream of or within locomotory behavior; neuromuscular process controlling balance; and neuronal action potential. Predicted to be located in ciliary membrane; cytoplasm; and nucleus. Predicted to be active in plasma membrane. Is expressed in several structures, including alimentary system; ear; genitourinary system; nervous system; and skeleton. Orthologous to human GPR88 (G protein-coupled receptor 88).

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

AW061286; G protein-coupled receptor 88; probable G-protein coupled receptor 88; St; Strg; striatum-specific G-protein coupled receptor

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	GPR88 (G protein-coupled receptor 88)	HGNC	EggNOG, Ensembl, HGNC, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Rattus norvegicus (Norway rat):	Gpr88 (G-protein coupled receptor 88)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Gpr88 (G protein-coupled receptor 88)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	GPR88 (G protein-coupled receptor 88)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	GPR88 (G protein-coupled receptor 88)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Gpr88 (G protein-coupled receptor 88)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	GPR88 (G protein-coupled receptor 88)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	GPR88 (G protein-coupled receptor 88)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Gpr88 (G protein-coupled receptor 88)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Rattus norvegicus (Norway rat):	Gpr88 (G-protein coupled receptor 88)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	GPR88 (G protein-coupled receptor 88)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	gpr88 (G protein-coupled receptor 88)	Alliance	DIOPT (ZFIN)
Xenopus tropicalis (tropical clawed frog):	gpr88	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PhylomeDB)

Latest Assembly:

GRCm39 - Mouse Genome Assembly GRCm39

Position:

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	3	116,043,304 - 116,047,123 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	3	116,043,303 - 116,047,152 (-)	Ensembl		GRCm39 Ensembl
GRCm38	3	116,249,654 - 116,253,540 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	3	116,249,654 - 116,253,503 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	3	115,952,572 - 115,956,402 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	3	116,241,660 - 116,245,458 (-)	NCBI		MGSCv36	mm8
Celera	3	122,679,632 - 122,683,466 (-)	NCBI		Celera
Cytogenetic Map	3	G1	NCBI
cM Map	3	50.23	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Childhood-Onset Chorea with Psychomotor Retardation (ISO)

maple syrup urine disease (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-catechin (ISO)

(S)-nicotine (EXP)

17alpha-ethynylestradiol (ISO)

2,2',4,4',5,5'-hexachlorobiphenyl (EXP)

2,2',5,5'-tetrachlorobiphenyl (EXP)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

3,3',4,4',5-pentachlorobiphenyl (ISO)

acetamide (ISO)

acrylamide (ISO)

aflatoxin B1 (ISO)

all-trans-retinoic acid (EXP)

alpha-Zearalanol (ISO)

ammonium chloride (ISO)

antirheumatic drug (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

carbon nanotube (EXP)

CGP 52608 (ISO)

cobalt dichloride (ISO)

cocaine (EXP,ISO)

Cuprizon (ISO)

cyclosporin A (ISO)

DDT (ISO)

dextran sulfate (EXP)

dichloroacetic acid (EXP)

endosulfan (ISO)

ethanol (EXP)

fenamidone (EXP)

flavonoids (ISO)

folic acid (EXP)

glyphosate (EXP,ISO)

ifosfamide (ISO)

lead(0) (ISO)

lipopolysaccharide (ISO)

mono(2-ethylhexyl) phthalate (EXP)

morphine (EXP)

nicotine (EXP)

paracetamol (ISO)

PCB138 (EXP)

perfluorononanoic acid (ISO)

perfluorooctanoic acid (ISO)

phenobarbital (ISO)

resveratrol (ISO)

S-(1,2-dichlorovinyl)-L-cysteine (ISO)

sodium arsenite (ISO)

Soman (ISO)

titanium dioxide (EXP)

trimellitic anhydride (EXP)

valproic acid (ISO)

vinclozolin (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

adenylate cyclase-modulating G protein-coupled receptor signaling pathway (ISO)

adrenergic receptor signaling pathway (IEA)

cellular response to light stimulus (IBA)

G protein-coupled receptor signaling pathway (IBA,ISO,ISS)

locomotory behavior (IMP)

motor learning (IMP)

neuromuscular process controlling balance (IMP)

neuronal action potential (IMP)

phototransduction (IBA)

signal transduction (IEA)

Cellular Component

cell projection (IEA)

ciliary membrane (ISO)

cilium (ISO)

cytoplasm (ISO,ISS)

membrane (IEA)

nucleus (ISO,ISS)

plasma membrane (IBA,ISO,ISS)

Molecular Function

beta2-adrenergic receptor activity (ISO,ISS)

cytoskeletal motor activity (IMP)

G protein-coupled photoreceptor activity (IBA)

G protein-coupled receptor activity (ISS)

transmembrane signaling receptor activity (ISS)

Phenotype Annotations Click to see Annotation Detail View

Mammalian Phenotype

abnormal associative learning (IAGP)

abnormal behavior (IAGP)

abnormal behavioral response to xenobiotic (IAGP)

abnormal excitatory postsynaptic currents (IAGP)

abnormal GABA-mediated receptor currents (IAGP)

abnormal habituation to a new environment (IAGP)

abnormal inhibitory postsynaptic currents (IAGP)

abnormal motor learning (IAGP)

abnormal nervous system electrophysiology (IAGP)

abnormal nervous system physiology (IAGP)

abnormal nest building behavior (IAGP)

abnormal neuron physiology (IAGP)

abnormal spatial working memory (IAGP)

circling (IAGP)

decreased anxiety-related response (IAGP)

decreased dendritic spine density (IAGP)

decreased grip strength (IAGP)

decreased grooming behavior (IAGP)

decreased nervous system dopamine level (IAGP)

decreased vertical activity (IAGP)

enhanced behavioral response to amphetamine (IAGP)

enhanced spatial learning (IAGP)

hyperactivity (IAGP)

impaired active avoidance behavior (IAGP)

impaired coordination (IAGP)

impaired cued conditioning behavior (IAGP)

increased excitatory postsynaptic current amplitude (IAGP)

increased exploration in new environment (IAGP)

increased nervous system dopamine level (IAGP)

increased serotonin level (IAGP)

increased stereotypic behavior (IAGP)

References

References - curated

#	Reference Title	Reference Citation
1.	Electronic Transfer of Homolog Data	MGD and Homologene mouse data transfer
2.	MGDs mouse GO annotations	MGD data from the GO Consortium
3.	A novel G-protein-coupled receptor gene expressed in striatum.	Mizushima K, etal., Genomics 2000 Nov 1;69(3):314-21.
4.	Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.	Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
5.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:8889548	PMID:12477932	PMID:14681479	PMID:15489334	PMID:16141072	PMID:16602821	PMID:18287559	PMID:19796684	PMID:21368124	PMID:21813695	PMID:21873635	PMID:23064379
PMID:24952328	PMID:24952961	PMID:25134728	PMID:26188284	PMID:26188600	PMID:27405468	PMID:27570825	PMID:28154160	PMID:28433741	PMID:28700108	PMID:28729439	PMID:28855710
PMID:28882062	PMID:28883788	PMID:29110094	PMID:29466446	PMID:29580570	PMID:30529950	PMID:30635555	PMID:31346000	PMID:31666199	PMID:32003745	PMID:33078498	PMID:34247243
PMID:34702951	PMID:35755440	PMID:36867535

Genomics

Comparative Map Data

Gpr88
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	3	116,043,304 - 116,047,123 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	3	116,043,303 - 116,047,152 (-)	Ensembl		GRCm39 Ensembl
GRCm38	3	116,249,654 - 116,253,540 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	3	116,249,654 - 116,253,503 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	3	115,952,572 - 115,956,402 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	3	116,241,660 - 116,245,458 (-)	NCBI		MGSCv36	mm8
Celera	3	122,679,632 - 122,683,466 (-)	NCBI		Celera
Cytogenetic Map	3	G1	NCBI
cM Map	3	50.23	NCBI

GPR88
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	100,538,139 - 100,542,021 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	100,538,139 - 100,542,021 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	1	101,003,695 - 101,007,577 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	100,776,316 - 100,780,171 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	1	100,715,713 - 100,719,591	NCBI
Celera	1	99,264,881 - 99,268,736 (+)	NCBI		Celera
Cytogenetic Map	1	p21.2	NCBI
HuRef	1	99,127,815 - 99,131,777 (+)	NCBI		HuRef
CHM1_1	1	101,119,832 - 101,123,687 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	1	100,386,520 - 100,390,416 (+)	NCBI		T2T-CHM13v2.0

Gpr88
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	2	206,876,373 - 206,885,034 (-)	NCBI		GRCr8
mRatBN7.2	2	204,191,443 - 204,199,576 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	2	204,191,427 - 204,199,733 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	2	211,854,881 - 211,859,447 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	2	209,749,992 - 209,754,559 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	2	204,567,036 - 204,571,603 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	2	219,258,346 - 219,263,819 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	2	219,258,347 - 219,262,901 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	2	237,334,864 - 237,340,370 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	2	212,460,210 - 212,464,764 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	2	212,422,963 - 212,427,518 (-)	NCBI
Celera	2	196,686,707 - 196,691,227 (-)	NCBI		Celera
Cytogenetic Map	2	q42	NCBI

Gpr88
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0	NW_004955435	5,268,746 - 5,271,237 (+)	NCBI	ChiLan1.0	ChiLan1.0

GPR88
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	1	126,485,809 - 126,489,693 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	1	125,643,969 - 125,649,248 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	1	103,194,721 - 103,200,712 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	1	101,909,929 - 101,911,740 (+)	NCBI	panpan1.1	PanPan1.1	panPan2

GPR88
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	6	49,473,399 - 49,478,504 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	6	49,475,536 - 49,476,669 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	6	52,146,852 - 52,148,102 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	6	49,821,259 - 49,822,509 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	6	49,821,259 - 49,822,413 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	6	49,513,852 - 49,515,102 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	6	49,493,123 - 49,494,373 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	6	49,923,358 - 49,924,608 (-)	NCBI		UU_Cfam_GSD_1.0

Gpr88
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405058	110,853,688 - 110,857,668 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936748	657,587 - 662,769 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936748	657,876 - 662,831 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

GPR88
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	4	117,618,733 - 117,619,884 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	4	117,616,596 - 117,623,752 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	4	129,210,683 - 129,214,011 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

GPR88
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	20	32,799,493 - 32,803,502 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	20	32,801,372 - 32,802,526 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666038	25,254,394 - 25,259,371 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Gpr88
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624857	3,435,952 - 3,440,055 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624857	3,435,286 - 3,440,746 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Gpr88
141 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	524
Count of miRNA genes:	393
Interacting mature miRNAs:	435
Transcripts:	ENSMUST00000090473
Prediction methods:	Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCm39)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1301904	Iba2_m	induction of brown adipocytes 2 (mouse)			Not determined		3	82147043	116147184	Mouse
1300752	Ap6q_m	alcohol preference 6 QTL (mouse)			Not determined		3	100372912	147045722	Mouse
26884382	Bzwq1_m	bi-zygomatic width QTL 1, 5 week (mouse)					3	52207421	137205761	Mouse
11041900	Lmr11a_m	leishmaniasis resistance 11a (mouse)					3	83463991	117464137	Mouse
14746984	Manh54_m	mandible shape 54 (mouse)					3	85289152	119289152	Mouse
12910796	Pwbwq6_m	post-weaning body weight QTL 6 (mouse)					3	110084357	135715812	Mouse
12738440	Twq3_m	testis weight QTL 3 (mouse)					3	87228015	121228015	Mouse
25314313	Syncl1_m	synaptonemal complex length 1 (mouse)					3	67907333	128393649	Mouse
1301272	Cfsw1_m	cystic fibrosis survival to weaning 1 (mouse)			Not determined		3	83882912	117883044	Mouse
12910793	Pwbwq7_m	post-weaning body weight QTL 7 (mouse)					3	110084357	135715812	Mouse
26884436	Zlq3_m	zygomatic length QTL 3, 10 week (mouse)					3	3265060	142405761	Mouse
11533920	Mvb3_m	modifier of vibrator 3 (mouse)					3	98635284	132635383	Mouse
10766455	Sle22_m	systematic lupus erythematosus susceptibility 22 (mouse)					3	90376936	124377072	Mouse
1301381	Bomb1_m	bone marrow pre-B 1 (mouse)			Not determined		3	111133243	145133417	Mouse
14747001	Mancz4_m	mandible centroid size 4 (mouse)					3	90378017	124378017	Mouse
1300619	Cdcs1_m	cytokine deficiency colitis susceptibility 1 (mouse)			Not determined		3	109834882	143835005	Mouse
26884419	Bzwq6_m	bi-zygomatic width QTL 6, 10 week (mouse)					3	100607316	137205761	Mouse
1301705	Sles3_m	systemic lupus erythmatosus suppressor 3 (mouse)			Not determined		3	37174862	143353183	Mouse
12910815	Ogrq1_m	overall growth rate QTL 1 (mouse)					3	110084357	135715812	Mouse
13207570	Tcq12_m	total cholesterol QTL 12 (mouse)					3	16504164	130163649	Mouse
1357583	Sle18_m	systematic lupus erythematosus susceptibility 18 (mouse)			Not determined		3	87208904	125316236	Mouse
12792984	Modn1_m	modifier of Dstn neovascularization 1 (mouse)					3	98635284	132635383	Mouse
26884422	Cvht7_m	cranial vault height 7, 16 week (mouse)					3	28954149	118893649	Mouse
4142178	Ctrq2_m	C. trachomatis resistance QTL 2 (mouse)			Not determined		3	89139967	137453008	Mouse
1302093	Orgwq5_m	organ weight QTL 5 (mouse)			Not determined		3	107376936	147304689	Mouse
10043955	Wt10q4_m	body weight, 10 weeks, QTL 4 (mouse)			Not determined		3	98624041	132624197	Mouse
8655599	Cia5c_m	collagen induced arthritis QTL 5c (mouse)			Not determined		3	107376936	125316237	Mouse
4142099	Cq3_m	cholesterol QTL 3 (mouse)			Not determined		3	84888918	118889067	Mouse
11039512	Ltpr3b_m	Leishmania tropica response 3b (mouse)					3	83463991	117464137	Mouse
1302114	Tbs1_m	tuberculosis severity 1 (mouse)			Not determined		3	98924105	132924250	Mouse
27226733	Tibmd6_m	tibia midshaft diameter 6, 16 week (mouse)					3	101307316	149805637	Mouse
27226732	Tibmd3_m	tibia midshaft diameter 3, 10 week (mouse)					3	96607316	147805636	Mouse
1301349	Pgia26_m	proteoglycan induced arthritis 26 (mouse)			Not determined		3	92251533	126251650	Mouse
1302052	Etohcta4_m	ethanol conditioned taste aversion 4 (mouse)			Not determined		3	91000105	125008748	Mouse
1302056	Orgwq4_m	organ weight QTL 4 (mouse)			Not determined		3	30067588	147304689	Mouse
11039507	Ltpr3g_m	Leishmania tropica response 3g (mouse)					3	83463991	117464137	Mouse
11039508	Ltpr3f_m	Leishmania tropica response 3f (mouse)					3	83463991	117464137	Mouse
11039509	Ltpr3e_m	Leishmania tropica response 3e (mouse)					3	83463991	117464137	Mouse
11039510	Ltpr3d_m	Leishmania tropica response 3d (mouse)					3	83463991	117464137	Mouse
1301805	Mors2_m	modifier of obesity related sterility 2 (mouse)			Not determined		3	103482659	137482783	Mouse
11039511	Ltpr3c_m	Leishmania tropica response 3c (mouse)					3	83463991	117464137	Mouse
1301100	Bdt2_m	bone density traits 2 (mouse)			Not determined		3	114736617	148736784	Mouse

Markers in Region

AW061286

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
GRCm38	3	116,249,877 - 116,249,961	UniSTS	GRCm38
MGSCv37	3	115,952,795 - 115,952,879	UniSTS	GRCm37
Celera	3	122,679,855 - 122,679,939	UniSTS
Cytogenetic Map	3	G1	UniSTS
Whitehead/MRC_RH	3	1358.35	UniSTS

Gpr88

Mouse Assembly	Chr	Position (strand)	Source	JBrowse
GRCm38	3	116,250,519 - 116,251,521	UniSTS	GRCm38
MGSCv37	3	115,953,437 - 115,954,439	UniSTS	GRCm37
Celera	3	122,680,497 - 122,681,499	UniSTS
Cytogenetic Map	3	G1	UniSTS
cM Map	3		UniSTS

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001411424	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001411425	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001411426	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_022427	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AB042408	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AB042409	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AC122888	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC029939	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC051941	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC157981	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH466532	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSMUST00000090473 ⟹ ENSMUSP00000087959

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	3	116,043,303 - 116,047,152 (-)	Ensembl
GRCm38.p6 Ensembl	3	116,249,654 - 116,253,503 (-)	Ensembl

Ensembl Acc Id:

ENSMUST00000197759 ⟹ ENSMUSP00000143586

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	3	116,046,212 - 116,046,738 (-)	Ensembl
GRCm38.p6 Ensembl	3	116,252,563 - 116,253,089 (-)	Ensembl

Ensembl Acc Id:

ENSMUST00000199128

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39 Ensembl	3	116,046,325 - 116,047,112 (-)	Ensembl
GRCm38.p6 Ensembl	3	116,252,676 - 116,253,463 (-)	Ensembl

RefSeq Acc Id:

NM_001411424 ⟹ NP_001398353

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	3	116,043,304 - 116,047,123 (-)	NCBI

RefSeq Acc Id:

NM_001411425 ⟹ NP_001398354

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	3	116,043,304 - 116,047,123 (-)	NCBI

RefSeq Acc Id:

NM_001411426 ⟹ NP_001398355

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	3	116,043,304 - 116,047,123 (-)	NCBI

RefSeq Acc Id:

NM_022427 ⟹ NP_071872

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm39	3	116,043,304 - 116,047,123 (-)	NCBI
GRCm38	3	116,249,654 - 116,253,484 (-)	NCBI
MGSCv37	3	115,952,572 - 115,956,402 (-)	RGD
Celera	3	122,679,632 - 122,683,466 (-)	RGD
cM Map	3		ENTREZGENE

Sequence:

show sequence

TGGGTTTGCCACATCAGCCAGCGCTCTTGCTTGGAGCACAGGGTGCGCTCCTCTCCAGCTCAGT
TTCTTCTGCTCTTGTAGCCAGGCATCTTCGCTGCTGCTGCCTGCCTGCCCACCCTTCTGGGCTT
GCAGCCTACCGCTTGACTTTCTCCAATTCTACTGCCAGCTGAGGAGACTCCCCACAGCTGTTGG
CTCCTGCCTGGGACCATGTGTGGGGATGCTGCACGGGAGAAGCAAGGCGCTTGCTCCTGGCACG
GGTCCCAGCTCAGTTTCTCCTGTTGACTTCTGGACCACAGATGCTGCTGCCGAGGAGGTATTTC
CTGGCATCTCTCCCTCTGCTATCACCAGCTAAGGACTGGCCCCAAATCAAGCAGGCAAGTGCCA
GGATGGGCCACGCTACACGAAGCCAACGCTAGGGCGCGAGGTGTGAAGAGTTGGCCAGAATGAC
CAACTCCTCCTCCACTTCGACCTCCACCACTACCGGGGGATCGCTGCTGCTGCTCTGCGAGGAA
GAAGAATCGTGGGCGGGCCGGCGGATCCCGGTGTCTCTCCTGTACTCGGGCCTGGCCATCGGGG
GCACGCTGGCCAACGGTATGGTCATCTATCTCGTGTCGTCCTTCCGAAAGCTGCAGACCACCAG
CAACGCCTTCATCGTGAATGGCTGCGCCGCGGATCTCAGCGTCTGCGCCCTCTGGATGCCACAG
GAGGCGGTGCTGGGGCTCCTGCCCTCGGGCTCCGCGGAGCCCCCGGGGGACTGGGACGGTGGCG
GAGGCAGCTACCGCCTGCTCCGGGGCGGGTTGTTGGGCCTCGGGCTCACTGTGTCCCTTCTGTC
CCATTGCCTCGTGGCGCTGAACCGCTACCTGCTCATCACCAGGGCGCCTGCCACCTACCAGGTG
CTCTACCAACGGCGCCACACGGTGGGCATGCTGGCACTGTCCTGGGCGCTCGCCTTGGGTCTGG
TGCTGCTGCTCCCGCCCTGGGCTCCTAAGCCCGGAGCCGAGCCACCGCAAGTCCACTACCCCGC
GCTCCTGGCGGCGGGAGCGCTGCTTGCGCAGACGGCGCTGCTGTTGCACTGCTACCTGGGCATC
GTGCGCCGCGTGCGCGTCAGCGTCAAGCGGGTCAGCGTGCTCAACTTCCACCTGCTGCACCAGC
TACCCGGCTGCGCCGCCGCCGCCGCCGCCTTCCCCGCCGCCCCGCACGCGCCGGGTCCGGGAGG
CGCCGCGCATCCCGCGCAGCCTCAACCCCTGCCGGCCGCTCTGCAGCCTCGCCGGGCGCAGCGG
CGTCTCAGCGGCTTGTCGGTGCTGCTGCTCTGCTGCGTCTTCCTGCTGGCCACGCAGCCGCTGG
TGTGGGTGAGCCTGGCCAGTGGCTTCTCCCTCCCGGTGCCCTGGGGCGTGCAGGCGGCCAGCTG
GCTCCTGTGCTGCGCCCTGTCGGCGCTCAACCCGCTGCTCTACACGTGGAGGAACGAGGAGTTC
CGCAGATCCGTGCGATCTGTCCTGCCGGGCGTCGGGGACGCGGCTGCGGCCGCCGCGGCCGCCA
CCGCGGTGCCAGCCATGTCCCAGGCGCAACTGGGTACCCGGGCGGCTGGCCAGCACTGGTAACA
CACCTTGCTTGGAGAGGCTTCCTAAGCCACCTGCCGCACTGCCTCCTTCTTTTGTAAGCTATCC
CCAGCCCCAGGGAAGATCCCAGTGGAGAACATTTTGCCTTCCTCCCCAGTGCAATACCAGAACC
AAGGTCTTCCCCTAAAGGGAGTCCCAATTGTGTGCGGCCATTGACGTTTACCCTTTTGTTTCTG
TGTTTTAAAGACACCCGTGGGTCCATCCAGACACTCAGACTGCAAGGACTTGTAAACTGGCATT
TTTAGAGAACCAGTTAATTTATTTCAAGTTTGCTTTTGAAAAAGAGCTTTCATATCATAACGTA
CAACCCTTCCAACCTCCACCGTCTTATATACGAAGCGCCTTGAGTGTGTGTGTGCATGAGCCAA
AGGGAATACCGTTGATGAAGAGACTGTGTGTAGATAGTATCCTAACCACACTTTCTTCTGTTAG
AGTTTAGTCTTTGTATATTGACCTGGAAGAGTGAAACCACAGGTGTGTACACCGTCGTGAGTTG
CCACTGAGACCTCAGGCCCTTTATTCTTAAAAGGGCTTTTTTTATTGAGTCATTTTTGAAATGA
GATTGACTCTCAGCCAGTGAGGAAACAAACCAAATTTATTATTTTACTCTCCTCTCTATTTATT
TCTAAGGTGGAAAGCTACCGTCGAGTGTTAAAGCGAAAAAATGTCAAGTTTTGGATTGGTCAGA
AACCAGAAATGGAATTTTAAAAGCAAAAACAGGGGGAGCTATCTATTTTGGGTAGCACTTTCAC
ATATTCTGAAGCATGCACACTTCTTGCTACCCACATTTGTAACTGATTTATTTGCCTCTGAGTG
TGATTGCAGCTTTGAACATTCTGTACTATAATGGTTGCTAAGGGGAATGACTCCTGTAGTCTCT
TTAAAATATCTCAATGCACATGACATAATTAAACACTAATACCATAATTGCATAGCTAATGTTA
GCTGCCATTGCATGCTCCTAGATGTTAGAACTTACTGGGCATGTGGTACACAAAGCAATACCCA
TTAGACAAGGACATTTTACTTCTTCCAGACACCAGAAGAAAAGGTCTTTTAATCATCTGAAAAG
AGATGTAGATGAACCCGTGGCTCCCTAGAGTTCTTGTCTTGACCTGGCTTATGAGAAAACTCCC
ATTTGGGGACTTTATCTCCCAAATGAAACCAATGGTCAGGGTGATAAAATTCAGATTGGCTCCA
TCAAGTTACCTGTGCGTTTTAGGGGTTAAACAAGCCACACGTTAGGAAGTAACACTGTTTTATG
TTGTTCATATATATTACAAAAACATTTATTATTAGTATCATGTCTGTTGAAGATGGAATCAGGC
AGACAGTTATGCAGAAGGAGAATATTTCGAATGGGACTCTGTTCTCCAATGTATCAGTTGAGGT
TTGCAGTCTTCATCTTTGATTTCCTAAATGTATAGATGCATTTACAATGTACAAAAAACAAAAA
CAAAAACACTGAAATCGTTTTGTAAAATTAAACAGGGAAGAAAGTAACAGGAGGCCTAGACCAG
TCTGTTATCCACATAAAATCTGGGGCCAAATAGCCTCAATTAACTGTGTAATTCAGGAGCAAAG
ACAGCTTGCTTTGTTGCACTCTTGGACCAAGAATGGTAAGAACATTTGTATTTTTGAAAAAATT
GGGAGACACGGGAAACAGATATTTTATAGCAAGGCAAAATAAAATAAATATGTTTGTCACTAAC
AATACGTTGGCAGTCATGTCATTAACCAAACTGTGTGCATGTGTCATTTTTCTCTTACGAAGAT
TTCTTCTGTTTCCAGTTTCCTGGATTCAGATATTTAATTAAAGTTTCCATAATGCTTC

hide sequence

Protein Sequences


Protein RefSeqs	NP_001398353	(Get FASTA)	NCBI Sequence Viewer
	NP_001398354	(Get FASTA)	NCBI Sequence Viewer
	NP_001398355	(Get FASTA)	NCBI Sequence Viewer
	NP_071872	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH51941	(Get FASTA)	NCBI Sequence Viewer
	AAI57982	(Get FASTA)	NCBI Sequence Viewer
	BAB18245	(Get FASTA)	NCBI Sequence Viewer
	BAB18246	(Get FASTA)	NCBI Sequence Viewer
	EDL12386	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSMUSP00000087959
	ENSMUSP00000087959.6
	ENSMUSP00000143586.2
GenBank Protein	Q9EPB7	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_071872 ⟸ NM_022427

- UniProtKB:

Q9EPB7 (UniProtKB/Swiss-Prot), B2RXU4 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MTNSSSTSTSTTTGGSLLLLCEEEESWAGRRIPVSLLYSGLAIGGTLANGMVIYLVSSFRKLQT
TSNAFIVNGCAADLSVCALWMPQEAVLGLLPSGSAEPPGDWDGGGGSYRLLRGGLLGLGLTVSL
LSHCLVALNRYLLITRAPATYQVLYQRRHTVGMLALSWALALGLVLLLPPWAPKPGAEPPQVHY
PALLAAGALLAQTALLLHCYLGIVRRVRVSVKRVSVLNFHLLHQLPGCAAAAAAFPAAPHAPGP
GGAAHPAQPQPLPAALQPRRAQRRLSGLSVLLLCCVFLLATQPLVWVSLASGFSLPVPWGVQAA
SWLLCCALSALNPLLYTWRNEEFRRSVRSVLPGVGDAAAAAAAATAVPAMSQAQLGTRAAGQHW

hide sequence

Ensembl Acc Id:

ENSMUSP00000087959 ⟸ ENSMUST00000090473

Ensembl Acc Id:

ENSMUSP00000143586 ⟸ ENSMUST00000197759

RefSeq Acc Id:	NP_001398354 ⟸ NM_001411425
- UniProtKB:	Q9EPB7 (UniProtKB/Swiss-Prot), B2RXU4 (UniProtKB/TrEMBL)

RefSeq Acc Id:	NP_001398353 ⟸ NM_001411424
- UniProtKB:	Q9EPB7 (UniProtKB/Swiss-Prot), B2RXU4 (UniProtKB/TrEMBL)

RefSeq Acc Id:	NP_001398355 ⟸ NM_001411426
- UniProtKB:	Q9EPB7 (UniProtKB/Swiss-Prot), B2RXU4 (UniProtKB/TrEMBL)

Protein Domains

G-protein coupled receptors family 1 profile

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q9EPB7-F1-model_v2	AlphaFold	Q9EPB7	1-384	view protein structure

Promoters

RGD ID:

6833912

Promoter ID:

MM_KWN:35886

Type:

CpG-Island

SO ACC ID:

SO:0000170

Source:

MPROMDB

Tissues & Cell Lines:

Lung

Transcripts:

NM_022427

Position:

Mouse Assembly	Chr	Position (strand)	Source
MGSCv36	3	115,955,851 - 115,956,351 (-)	MPROMDB

RGD ID:

6882168

Promoter ID:

EPDNEW_M4535

Type:

initiation region

Name:

Gpr88_1

Description:

Mus musculus G-protein coupled receptor 88 , mRNA.

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Mouse Assembly	Chr	Position (strand)	Source
GRCm38	3	116,253,474 - 116,253,534	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	MGI:1927653	AgrOrtholog
Ensembl Genes	ENSMUSG00000068696	Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript	ENSMUST00000090473	ENTREZGENE
	ENSMUST00000090473.7	UniProtKB/Swiss-Prot
	ENSMUST00000197759.2	UniProtKB/TrEMBL
Gene3D-CATH	Rhodopsin 7-helix transmembrane proteins	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro	GPCR_opsins	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	GPCR_Rhodpsn	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	GPCR_Rhodpsn_7TM	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	mmu:64378	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD	MGI:1927653	ENTREZGENE
NCBI Gene	64378	ENTREZGENE
PANTHER	G-PROTEIN COUPLED RECEPTOR 88-RELATED	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	OPSIN	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	7tm_1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Gpr88	PhenoGen
PRINTS	GPCRRHODOPSN	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE	G_PROTEIN_RECEP_F1_2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP	Family A G protein-coupled receptor-like	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	A0A0G2JGJ3_MOUSE	UniProtKB/TrEMBL
	B2RXU4	ENTREZGENE, UniProtKB/TrEMBL
	GPR88_MOUSE	UniProtKB/Swiss-Prot, ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - OMIM

Mammalian Phenotype

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - OMIM

Mammalian Phenotype