Ehd3 (EH-domain containing 3) - Rat Genome Database

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Gene: Ehd3 (EH-domain containing 3) Rattus norvegicus
Analyze
Symbol: Ehd3
Name: EH-domain containing 3
RGD ID: 621762
Description: Predicted to enable protein-macromolecule adaptor activity. Predicted to be involved in several processes, including cytosolic transport; protein homooligomerization; and regulation of heart contraction. Predicted to act upstream of or within regulation of cardiac muscle cell membrane potential. Predicted to be located in ciliary pocket membrane. Predicted to be active in cytoplasmic vesicle; perinuclear region of cytoplasm; and plasma membrane. Orthologous to human EHD3 (EH domain containing 3); PARTICIPATES IN endocytosis pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2-methoxyethanol; 3,7-dihydropurine-6-thione.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: EH domain-containing protein 3; Ehd2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8627,392,709 - 27,417,445 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl627,392,709 - 27,417,445 (-)EnsemblGRCr8
mRatBN7.2621,640,861 - 21,665,601 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl621,639,290 - 21,665,236 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx621,969,572 - 21,994,301 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0622,285,418 - 22,310,143 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0621,765,853 - 21,790,578 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0625,076,012 - 25,102,457 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl625,074,955 - 25,100,977 (+)Ensemblrn6Rnor6.0
Rnor_5.0634,923,729 - 34,949,869 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4621,638,705 - 21,686,023 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera621,191,963 - 21,214,991 (-)NCBICelera
RGSC_v3.1621,641,657 - 21,688,976 (-)NCBI
Cytogenetic Map6q14NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
1,1-dichloroethene  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,6-dimethoxyphenol  (ISO)
2-hydroxypropanoic acid  (ISO)
2-methoxyethanol  (EXP)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
3,7-dihydropurine-6-thione  (EXP)
3-methylcholanthrene  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (EXP,ISO)
4-hydroxyphenyl retinamide  (ISO)
4-phenylbutyric acid  (ISO)
5-aza-2'-deoxycytidine  (ISO)
Aflatoxin B2 alpha  (ISO)
aldehydo-D-glucose  (EXP)
ammonium chloride  (EXP)
aristolochic acid A  (ISO)
benzo[a]pyrene  (ISO)
benzo[b]fluoranthene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol AF  (ISO)
bisphenol F  (EXP)
Butylbenzyl phthalate  (ISO)
C60 fullerene  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chloroprene  (EXP)
choline  (ISO)
cisplatin  (ISO)
D-glucose  (EXP)
dexamethasone  (ISO)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (EXP)
dimethylarsinic acid  (ISO)
dioxygen  (EXP)
doxorubicin  (ISO)
endosulfan  (EXP)
epoxiconazole  (ISO)
ethanol  (ISO)
fluoranthene  (ISO)
folic acid  (ISO)
furfural  (ISO)
gentamycin  (EXP)
glucose  (EXP)
GSK-J4  (ISO)
hydrogen sulfide  (ISO)
L-methionine  (ISO)
lead(0)  (ISO)
mercaptopurine  (EXP)
methidathion  (ISO)
nimesulide  (EXP)
nitrates  (ISO)
ozone  (ISO)
paracetamol  (EXP,ISO)
perfluorohexanesulfonic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phenobarbital  (ISO)
pirinixic acid  (ISO)
propiconazole  (ISO)
purine-6-thiol  (EXP)
rac-lactic acid  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
sodium chloride  (ISO)
starch  (EXP)
tamoxifen  (ISO)
tetrachloromethane  (ISO)
trichostatin A  (ISO)
triclosan  (ISO)
triphenyl phosphate  (ISO)
valproic acid  (ISO)
vorinostat  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
ciliary membrane  (IEA)
ciliary pocket membrane  (IEA,ISO,ISS)
cytoplasm  (IBA,IEA,ISO,ISS)
cytosol  (IEA)
early endosome  (IBA)
endocytic vesicle  (IBA,IEA,ISO)
perinuclear region of cytoplasm  (IBA,IEA,ISO)
plasma membrane  (IBA,IEA)
recycling endosome membrane  (IBA,IEA,ISO,ISS)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. EHD3: a protein that resides in recycling tubular and vesicular membrane structures and interacts with EHD1. Galperin E, etal., Traffic 2002 Aug;3(8):575-89.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
5. EHD2 interacts with the insulin-responsive glucose transporter (GLUT4) in rat adipocytes and may participate in insulin-induced GLUT4 recruitment. Park SY, etal., Biochemistry 2004 Jun 15;43(23):7552-62.
6. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
7. GOA pipeline RGD automated data pipeline
8. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:11423532   PMID:17233914   PMID:17251388   PMID:17634366   PMID:19139087   PMID:20489164   PMID:21423176   PMID:21791287   PMID:25686250   PMID:25825486   PMID:29476059  


Genomics

Comparative Map Data
Ehd3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8627,392,709 - 27,417,445 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl627,392,709 - 27,417,445 (-)EnsemblGRCr8
mRatBN7.2621,640,861 - 21,665,601 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl621,639,290 - 21,665,236 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx621,969,572 - 21,994,301 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0622,285,418 - 22,310,143 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0621,765,853 - 21,790,578 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0625,076,012 - 25,102,457 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl625,074,955 - 25,100,977 (+)Ensemblrn6Rnor6.0
Rnor_5.0634,923,729 - 34,949,869 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4621,638,705 - 21,686,023 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera621,191,963 - 21,214,991 (-)NCBICelera
RGSC_v3.1621,641,657 - 21,688,976 (-)NCBI
Cytogenetic Map6q14NCBI
EHD3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38231,234,152 - 31,269,451 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl231,233,961 - 31,269,451 (+)Ensemblhg38GRCh38
GRCh37231,457,018 - 31,492,317 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36231,310,707 - 31,344,764 (+)NCBIBuild 36Build 36hg18NCBI36
Build 34231,368,853 - 31,402,911NCBI
Celera231,299,596 - 31,333,966 (+)NCBICelera
Cytogenetic Map2p23.1NCBI
HuRef231,194,543 - 31,228,913 (+)NCBIHuRef
CHM1_1231,387,489 - 31,421,882 (+)NCBICHM1_1
T2T-CHM13v2.0231,278,316 - 31,313,593 (+)NCBIT2T-CHM13v2.0
Ehd3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391774,111,836 - 74,139,088 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1774,111,129 - 74,139,089 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm381773,804,841 - 73,832,093 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1773,804,134 - 73,832,094 (+)Ensemblmm10GRCm38
MGSCv371774,154,181 - 74,181,433 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361773,709,754 - 73,736,970 (+)NCBIMGSCv36mm8
Celera1778,096,325 - 78,123,512 (+)NCBICelera
Cytogenetic Map17E2NCBI
cM Map1745.2NCBI
Ehd3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495546912,953,645 - 12,984,430 (+)Ensembl
ChiLan1.0NW_00495546912,953,800 - 12,984,296 (+)NCBIChiLan1.0ChiLan1.0
EHD3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21295,230,506 - 95,265,388 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A95,234,481 - 95,269,366 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A31,245,908 - 31,280,485 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A31,317,432 - 31,353,312 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A31,317,432 - 31,353,312 (+)EnsemblpanPan2panpan1.1
EHD3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11724,828,289 - 24,854,990 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1724,828,372 - 24,853,400 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1724,622,571 - 24,649,257 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01725,392,047 - 25,418,779 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1725,392,095 - 25,417,697 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11724,695,316 - 24,722,054 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01724,757,373 - 24,784,106 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01724,857,360 - 24,884,084 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Ehd3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629268,943,443 - 68,974,729 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364931,864,755 - 1,896,097 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049364931,864,836 - 1,896,079 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
EHD3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl3108,100,401 - 108,134,906 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.13108,103,631 - 108,135,161 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
EHD3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11476,237,345 - 76,271,557 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1476,236,246 - 76,271,546 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604535,801,161 - 35,835,035 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ehd3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473813,032,604 - 13,062,795 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462473813,033,491 - 13,062,795 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Ehd3
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1719,411,935 - 19,437,055 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Ehd3
136 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:32
Count of miRNA genes:32
Interacting mature miRNAs:32
Transcripts:ENSRNOT00000010419
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
8552962Pigfal16Plasma insulin-like growth factor 1 level QTL 169.4blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)6197587946975879Rat
8693645Alc31Alcohol consumption QTL 313.70.038drinking behavior trait (VT:0001422)calculated ethanol drink intake rate (CMO:0001615)62328466429732046Rat
10401812Kidm54Kidney mass QTL 54kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)62009763565097635Rat
8552910Pigfal5Plasma insulin-like growth factor 1 level QTL 54.3blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)62265388967653889Rat
2292589Emca10Estrogen-induced mammary cancer QTL 100.048mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)62228825727729050Rat
10401800Kidm49Kidney mass QTL 49kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)62009763565097635Rat
1300164Rf15Renal function QTL 153.12renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)6323998948239989Rat
9589129Insul24Insulin level QTL 2419.060.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)6197587946975879Rat
7411603Foco13Food consumption QTL 135.50.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)6197587946975879Rat
1598843Cm63Cardiac mass QTL 632.6heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)6144788383Rat
7411542Bw127Body weight QTL 1275.50.001body mass (VT:0001259)body weight gain (CMO:0000420)6197587946975879Rat
2292616Ept15Estrogen-induced pituitary tumorigenesis QTL 154.4pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)6144788383Rat
9589048Scfw3Subcutaneous fat weight QTL 34.570.001subcutaneous adipose mass (VT:1000472)abdominal subcutaneous fat pad weight (CMO:0002069)6197587946975879Rat
2293839Kiddil2Kidney dilation QTL 24.8kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)62661831486868070Rat
1576309Emca7Estrogen-induced mammary cancer QTL 74mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)620859430113082285Rat
2301964Bp323Blood pressure QTL 3234.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)6186868070Rat
2293709Bss23Bone structure and strength QTL 235.180.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)6323998948239989Rat
2293650Bss31Bone structure and strength QTL 315.050.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)6323998948239989Rat
2293841Kiddil4Kidney dilation QTL 44.4kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)62661831486868070Rat
1300128Rf16Renal function QTL 163.89renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)6140163351Rat
70199Coreg1Compensatory renal growth QTL 111.8kidney mass (VT:0002707)compensatory renal growth score (CMO:0001894)61459947363457687Rat
2301972Bp325Blood pressure QTL 3254.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)61608937261967788Rat
1358190Ept1Estrogen-induced pituitary tumorigenesis QTL 14.4pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)6144788383Rat
2293656Bss28Bone structure and strength QTL 286.790.0001femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)6323998948239989Rat
1359023Bp272Blood pressure QTL 2722.5arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)62228825732981219Rat
1354664Slep2Serum leptin concentration QTL 24.49blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)62228825767288257Rat

Markers in Region
RH142835  
Rat AssemblyChrPosition (strand)SourceJBrowse
RH 3.4 Map8212.2UniSTS
Cytogenetic Map6q13UniSTS
RH141270  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2621,640,510 - 21,640,702 (-)MAPPERmRatBN7.2
Rnor_6.0625,101,042 - 25,101,233NCBIRnor6.0
Rnor_5.0634,948,457 - 34,948,648UniSTSRnor5.0
RGSC_v3.4621,638,355 - 21,638,546UniSTSRGSC3.4
Celera621,191,613 - 21,191,804UniSTS
Cytogenetic Map6q13UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 160 91 90 59 92 59 6 356 192 11 139 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000010419   ⟹   ENSRNOP00000010419
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl627,392,709 - 27,417,445 (-)Ensembl
mRatBN7.2 Ensembl621,639,290 - 21,665,236 (-)Ensembl
Rnor_6.0 Ensembl625,076,147 - 25,100,883 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000084773   ⟹   ENSRNOP00000068716
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl627,392,709 - 27,417,050 (-)Ensembl
mRatBN7.2 Ensembl621,639,290 - 21,665,206 (-)Ensembl
Rnor_6.0 Ensembl625,074,955 - 25,100,977 (+)Ensembl
RefSeq Acc Id: NM_138890   ⟹   NP_620245
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8627,392,709 - 27,417,445 (-)NCBI
mRatBN7.2621,640,861 - 21,665,601 (-)NCBI
Rnor_6.0625,076,147 - 25,100,883 (+)NCBI
Rnor_5.0634,923,729 - 34,949,869 (+)NCBI
RGSC_v3.4621,638,705 - 21,686,023 (-)RGD
Celera621,191,963 - 21,214,991 (-)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_620245 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAM14604 (Get FASTA)   NCBI Sequence Viewer  
  EDM02853 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000010419
  ENSRNOP00000010419.3
GenBank Protein Q8R491 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_620245   ⟸   NM_138890
- UniProtKB: Q8R491 (UniProtKB/Swiss-Prot),   A6H9Z8 (UniProtKB/TrEMBL),   A0A0G2JTH6 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000068716   ⟸   ENSRNOT00000084773
Ensembl Acc Id: ENSRNOP00000010419   ⟸   ENSRNOT00000010419
Protein Domains
Dynamin-type G   EF-hand   EH

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q8R491-F1-model_v2 AlphaFold Q8R491 1-535 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13694424
Promoter ID:EPDNEW_R4949
Type:initiation region
Name:Ehd3_1
Description:EH-domain containing 3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0625,076,191 - 25,076,251EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:621762 AgrOrtholog
BioCyc Gene G2FUF-38425 BioCyc
Ensembl Genes ENSRNOG00000007744 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000010419 ENTREZGENE
  ENSRNOT00000010419.4 UniProtKB/Swiss-Prot
Gene3D-CATH 1.10.268.20 UniProtKB/Swiss-Prot
  3.40.50.300 UniProtKB/Swiss-Prot
  EF-hand UniProtKB/Swiss-Prot
InterPro DUF5600 UniProtKB/Swiss-Prot
  Dynamin_N UniProtKB/Swiss-Prot
  EF-hand-dom_pair UniProtKB/Swiss-Prot
  EF_Hand_1_Ca_BS UniProtKB/Swiss-Prot
  EF_hand_dom UniProtKB/Swiss-Prot
  EH_dom UniProtKB/Swiss-Prot
  EHD_N UniProtKB/Swiss-Prot
  G_DYNAMIN_dom UniProtKB/Swiss-Prot
  P-loop_NTPase UniProtKB/Swiss-Prot
KEGG Report rno:192249 UniProtKB/Swiss-Prot
NCBI Gene 192249 ENTREZGENE
PANTHER DYNAMIN ASSOCIATED PROTEIN 160, ISOFORM D UniProtKB/Swiss-Prot
  EH DOMAIN UniProtKB/Swiss-Prot
Pfam DUF5600 UniProtKB/Swiss-Prot
  Dynamin_N UniProtKB/Swiss-Prot
  EF-hand_4 UniProtKB/Swiss-Prot
  EHD_N UniProtKB/Swiss-Prot
PhenoGen Ehd3 PhenoGen
PROSITE EF_HAND_1 UniProtKB/Swiss-Prot
  EF_HAND_2 UniProtKB/Swiss-Prot
  G_DYNAMIN_2 UniProtKB/Swiss-Prot
  PS50031 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000007744 RatGTEx
SMART SM00027 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF47473 UniProtKB/Swiss-Prot
  SSF52540 UniProtKB/Swiss-Prot
UniProt A0A0G2JTH6 ENTREZGENE, UniProtKB/TrEMBL
  A6H9Z8 ENTREZGENE, UniProtKB/TrEMBL
  EHD3_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2004-09-10 Ehd3  EH-domain containing 3      Symbol and Name status set to approved 1299863 APPROVED
2002-08-07 Ehd3  EH-domain containing 3      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_function interacts with GLUT4 in rat adipocytes 1304334