Sub1 (SUB1 regulator of transcription) - Rat Genome Database

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Gene: Sub1 (SUB1 regulator of transcription) Rattus norvegicus
Analyze
Symbol: Sub1
Name: SUB1 regulator of transcription
RGD ID: 621582
Description: Predicted to enable several functions, including DNA binding activity; identical protein binding activity; and transcription coactivator activity. Predicted to be involved in several processes, including RNA polymerase II promoter clearance; negative regulation of DNA duplex unwinding; and regulation of nucleobase-containing compound metabolic process. Predicted to be located in nucleolus and nucleoplasm. Predicted to be part of transcription regulator complex. Predicted to be active in nucleus. Orthologous to human SUB1 (SUB1 regulator of transcription); PARTICIPATES IN RNA polymerase III transcription pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; ammonium chloride.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: activated RNA polymerase II transcriptional coactivator p15; Loc192269; MGC109653; p14; PC4; positive cofactor 4; pR-ET2 encoded oncodevelopmental protein; RNA polymerase II transcriptional coactivator; Rpo2tc1; SUB1 homolog; SUB1 homolog (S. cerevisiae); SUB1 homolog, transcriptional regulator
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8262,735,379 - 62,747,545 (-)NCBIGRCr8
mRatBN7.2261,005,646 - 61,020,486 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl261,005,666 - 61,020,436 (-)EnsemblmRatBN7.2 Ensembl
mRatBN7.2 Ensembl243,299,239 - 43,299,924 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx268,138,134 - 68,150,187 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0266,259,692 - 66,271,744 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0261,261,040 - 61,273,093 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0262,019,902 - 62,034,704 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl262,022,567 - 62,034,628 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0282,656,079 - 82,670,881 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4261,418,076 - 61,430,139 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1261,346,310 - 61,356,225 (-)NCBI
Celera257,672,589 - 57,684,652 (+)NCBICelera
Cytogenetic Map2q16NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Transcription reinitiation by RNA polymerase III. Dieci G, etal., Biochim Biophys Acta. 2013 Mar-Apr;1829(3-4):331-41. doi: 10.1016/j.bbagrm.2012.10.009. Epub 2012 Nov 3.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Regulation of pol III transcription by nutrient and stress signaling pathways. Moir RD and Willis IM, Biochim Biophys Acta. 2013 Mar-Apr;1829(3-4):361-75. doi: 10.1016/j.bbagrm.2012.11.001. Epub 2012 Nov 16.
4. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
5. GOA pipeline RGD automated data pipeline
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. Comprehensive gene review and curation RGD comprehensive gene curation
8. Proteomics profiling of nuclear proteins for kidney fibroblasts suggests hypoxia, meiosis, and cancer may meet in the nucleus. Shakib K, etal., Proteomics. 2005 Jul;5(11):2819-38.
9. Molecular cloning and characterization of a cDNA clone for a protein specifically expressed in embryo as well as in a chemically induced pancreatic B cell tumor of rat. Soma G, etal., Biochem Biophys Res Commun 1984 Oct 15;124(1):164-71.
Additional References at PubMed
PMID:8062391   PMID:12477932   PMID:15489334   PMID:16415882   PMID:17130840   PMID:18836447   PMID:20458337   PMID:22206666   PMID:22658674   PMID:22681889   PMID:23376485   PMID:23390484  
PMID:25416956   PMID:28369605  


Genomics

Comparative Map Data
Sub1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8262,735,379 - 62,747,545 (-)NCBIGRCr8
mRatBN7.2261,005,646 - 61,020,486 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl261,005,666 - 61,020,436 (-)EnsemblmRatBN7.2 Ensembl
mRatBN7.2 Ensembl243,299,239 - 43,299,924 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx268,138,134 - 68,150,187 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0266,259,692 - 66,271,744 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0261,261,040 - 61,273,093 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0262,019,902 - 62,034,704 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl262,022,567 - 62,034,628 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0282,656,079 - 82,670,881 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4261,418,076 - 61,430,139 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1261,346,310 - 61,356,225 (-)NCBI
Celera257,672,589 - 57,684,652 (+)NCBICelera
Cytogenetic Map2q16NCBI
SUB1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38532,585,557 - 32,604,079 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl532,531,633 - 32,604,079 (+)EnsemblGRCh38hg38GRCh38
GRCh37532,585,663 - 32,604,185 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36532,621,434 - 32,637,820 (+)NCBINCBI36Build 36hg18NCBI36
Celera532,467,253 - 32,485,840 (+)NCBICelera
Cytogenetic Map5p13.3NCBI
HuRef532,553,427 - 32,572,031 (+)NCBIHuRef
CHM1_1532,587,724 - 32,606,294 (+)NCBICHM1_1
T2T-CHM13v2.0532,699,227 - 32,717,759 (+)NCBIT2T-CHM13v2.0
Sub1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391511,981,422 - 11,996,091 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1511,981,425 - 11,997,069 (-)EnsemblGRCm39 Ensembl
GRCm381511,981,336 - 11,996,038 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1511,981,339 - 11,996,983 (-)EnsemblGRCm38mm10GRCm38
MGSCv371511,911,094 - 11,925,762 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361511,926,064 - 11,940,732 (-)NCBIMGSCv36mm8
Celera1511,766,100 - 11,780,766 (-)NCBICelera
Cytogenetic Map15A1NCBI
cM Map155.9NCBI
Sub1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542618,380,117 - 18,394,627 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542618,380,680 - 18,394,627 (+)NCBIChiLan1.0ChiLan1.0
SUB1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2477,698,383 - 77,770,692 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1575,852,014 - 75,924,250 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0577,728,309 - 77,800,534 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1583,112,131 - 83,130,755 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl583,112,131 - 83,130,755 (-)Ensemblpanpan1.1panPan2
SUB1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1474,931,105 - 74,951,707 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl474,933,620 - 74,951,573 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha474,569,825 - 74,588,278 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0475,452,940 - 75,471,575 (-)NCBIROS_Cfam_1.0
UMICH_Zoey_3.1475,190,470 - 75,208,907 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0475,319,042 - 75,337,517 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0475,849,695 - 75,868,156 (-)NCBIUU_Cfam_GSD_1.0
Sub1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213223,122,805 - 223,137,782 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365188,233,338 - 8,249,549 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365188,236,026 - 8,249,007 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SUB1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1618,758,962 - 18,779,419 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11618,758,886 - 18,779,421 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
SUB1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1431,860,744 - 31,879,851 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl431,860,830 - 31,877,070 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607122,118,817 - 22,135,778 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Sub1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475922,009,266 - 22,037,394 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475922,010,097 - 22,027,807 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Sub1
57 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:246
Count of miRNA genes:190
Interacting mature miRNAs:206
Transcripts:ENSRNOT00000074446
Prediction methods:Miranda
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
61355Bp36Blood pressure QTL 362.9blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)25873687102844969Rat
731184Mamtr4Mammary tumor resistance QTL 40.0003mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)21649174061491740Rat
1357990Ael1Aortic elastin QTL 13.10.00091aorta elastin amount (VT:0003905)aortic elastin21907682564076825Rat
731167Glom4Glomerulus QTL 42.40.0082kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)22030467265304672Rat
2300168Bmd47Bone mineral density QTL 476.60.0001femur mineral mass (VT:0010011)bone mineral density (CMO:0001226)22066244865662448Rat
10402051Gdil2Gastrointestinal dilation QTL 2enteric ganglion morphology trait (VT:0001045)length of intestine affected by colonic aganglionosis to total length of colon ratio (CMO:0001836)22490385374786777Rat
1302794Stl27Serum triglyceride level QTL 274.40.0001blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)225413423143657569Rat
1358894Kidm24Kidney mass QTL 244.03kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)225413423157142209Rat
1358899Kidm23Kidney mass QTL 233.88kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)225413423157142209Rat
1358901Cm38Cardiac mass QTL 382heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)225413423157142209Rat
1358904Cm39Cardiac mass QTL 392.26heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)225413423157142209Rat
1358910Kidm27Kidney mass QTL 275.77kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)225413423157142209Rat
1358911Kidm28Kidney mass QTL 285.42kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)225413423157142209Rat
1358913Cm41Cardiac mass QTL 412.73heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)225413423203928301Rat
1358917Cm42Cardiac mass QTL 422.82heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)225413423203928301Rat
1358887Bw50Body weight QTL 502.39body mass (VT:0001259)body weight (CMO:0000012)225413652157142078Rat
1358908Bw49Body weight QTL 493.36body mass (VT:0001259)body weight (CMO:0000012)225413652157142078Rat
1354617Bp240Blood pressure QTL 2404arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)22691781781754745Rat
1354617Bp240Blood pressure QTL 2404arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)22691781781754745Rat
1354617Bp240Blood pressure QTL 2404arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)22691781781754745Rat
1354603Bp243Blood pressure QTL 2433.9arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)226917817127469484Rat
2290453Scl55Serum cholesterol level QTL 552.83blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)226917817136917119Rat
9590095Sffal3Serum free fatty acids level QTL 36.780.001blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)22715716072157160Rat
10755434Coatc7Coat color QTL 70.04794coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)23064806575648065Rat
10755436Coatc8Coat color QTL 80.02431coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)23502311780023117Rat
61371Edpm1Estrogen-dependent pituitary mass QTL 140.05pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)23513484188029593Rat
70174BpQTLCluster2Blood pressure QTL cluster 24.24arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)240067944102785628Rat
70174BpQTLCluster2Blood pressure QTL cluster 24.24arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)240067944102785628Rat
70174BpQTLCluster2Blood pressure QTL cluster 24.24arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)240067944102785628Rat
70174BpQTLCluster2Blood pressure QTL cluster 24.24arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)240067944102785628Rat
70174BpQTLCluster2Blood pressure QTL cluster 24.24arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)240067944102785628Rat
2293835Kiddil5Kidney dilation QTL 53.8kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)242804607157142209Rat
2293843Kiddil6Kidney dilation QTL 63.1kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)242804607182042367Rat
1298074Bp164Blood pressure QTL 1640.003arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)242804607202447032Rat
1298085Bp165Blood pressure QTL 1650.0006arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)242804607202447032Rat
61467Bp14Blood pressure QTL 142.2arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)243154682202446871Rat
61467Bp14Blood pressure QTL 142.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)243154682202446871Rat
2293676Bmd19Bone mineral density QTL 1910.70.0001femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)243162366111362592Rat
2293682Bmd24Bone mineral density QTL 248.90.0001femur mineral mass (VT:0010011)compact volumetric bone mineral density (CMO:0001730)243162366111362592Rat
2293671Bss44Bone structure and strength QTL 4410.970.0001lumbar vertebra morphology trait (VT:0010494)lumbar vertebra cortical cross-sectional area (CMO:0001690)243162366148478373Rat
631208Bw1Body weight QTL15.09mesenteric fat pad mass (VT:0010427)mesenteric fat pad weight to body weight ratio (CMO:0000654)24317101783575226Rat
1354601Slep1Serum leptin concentration QTL 15.39blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)243171017184114403Rat
631266Bp132Blood pressure QTL 1320.0005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)246123260202447032Rat
1354592Rf50Renal function QTL 503.5urine output (VT:0003620)timed urine volume (CMO:0000260)25382274774786777Rat
1331760Bp206Blood pressure QTL 2063.62454arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)256043031202447032Rat
6480225Gdil1Gastrointestinal dilation QTL 1enteric ganglion morphology trait (VT:0001045)length of intestine affected by colonic aganglionosis to total length of colon ratio (CMO:0001836)25666087974786777Rat
1582246Cm60Cardiac mass QTL 605.8heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)25760561276539510Rat
1558648Smcn1Smooth muscle cell number QTL 10.039blood vessel smooth muscle cell quantity (VT:0010525)aorta smooth muscle cell count per unit vessel length (CMO:0001646)259134147127460910Rat
5684990Bmd82Bone mineral density QTL 822.8tibia mineral mass (VT:1000283)bone mineral content (CMO:0001554)259324377103795077Rat
5684996Bmd85Bone mineral density QTL 854.70.024tibia mineral mass (VT:1000283)bone mineral density (CMO:0001226)259324377103795077Rat
61438Cia7Collagen induced arthritis QTL 74.60.0001joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)259324377141596857Rat
631500Bp99Blood pressure QTL 992.5arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)259324719102755241Rat
1578777Stresp15Stress response QTL 1520.05blood aldosterone amount (VT:0005346)plasma aldosterone level (CMO:0000551)259846005104846005Rat

Markers in Region
RH128729  
Rat AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map2q16UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 43 57 41 19 41 8 11 74 35 41 11 8
Low
Below cutoff

Sequence


RefSeq Acc Id: ENSRNOT00000074446   ⟹   ENSRNOP00000067467
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl243,299,239 - 43,299,924 (+)Ensembl
Rnor_6.0 Ensembl262,022,567 - 62,034,628 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000109925   ⟹   ENSRNOP00000077928
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl261,005,666 - 61,019,879 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000113169   ⟹   ENSRNOP00000092370
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl261,005,666 - 61,020,436 (-)Ensembl
RefSeq Acc Id: NM_001009618   ⟹   NP_001009618
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8262,735,379 - 62,747,442 (-)NCBI
mRatBN7.2261,008,309 - 61,020,372 (-)NCBI
Rnor_6.0262,022,565 - 62,034,628 (-)NCBI
Rnor_5.0282,656,079 - 82,670,881 (+)NCBI
RGSC_v3.4261,418,076 - 61,430,139 (-)RGD
Celera257,672,589 - 57,684,652 (+)RGD
Sequence:
RefSeq Acc Id: XM_006232043   ⟹   XP_006232105
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8262,735,379 - 62,747,545 (-)NCBI
mRatBN7.2261,005,646 - 61,020,486 (-)NCBI
Rnor_6.0262,019,902 - 62,034,704 (-)NCBI
Rnor_5.0282,656,079 - 82,670,881 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039101675   ⟹   XP_038957603
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8262,735,379 - 62,747,232 (-)NCBI
mRatBN7.2261,005,646 - 61,020,048 (-)NCBI
RefSeq Acc Id: XM_039101676   ⟹   XP_038957604
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8262,735,379 - 62,746,906 (-)NCBI
mRatBN7.2261,005,646 - 61,019,677 (-)NCBI
RefSeq Acc Id: XM_039101677   ⟹   XP_038957605
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8262,735,379 - 62,747,077 (-)NCBI
mRatBN7.2261,005,646 - 61,019,749 (-)NCBI
RefSeq Acc Id: XM_063281272   ⟹   XP_063137342
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8262,735,379 - 62,747,387 (-)NCBI
RefSeq Acc Id: NP_001009618   ⟸   NM_001009618
- UniProtKB: Q5M805 (UniProtKB/Swiss-Prot),   Q63396 (UniProtKB/Swiss-Prot),   A6KJQ6 (UniProtKB/TrEMBL),   A0A8I5ZJM1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006232105   ⟸   XM_006232043
- Peptide Label: isoform X1
- UniProtKB: Q5M805 (UniProtKB/Swiss-Prot),   Q63396 (UniProtKB/Swiss-Prot),   A6KJQ6 (UniProtKB/TrEMBL),   A0A8I5ZJM1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000067467   ⟸   ENSRNOT00000074446
RefSeq Acc Id: XP_038957603   ⟸   XM_039101675
- Peptide Label: isoform X1
- UniProtKB: Q63396 (UniProtKB/Swiss-Prot),   Q5M805 (UniProtKB/Swiss-Prot),   A6KJQ6 (UniProtKB/TrEMBL),   A0A8I5ZJM1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038957605   ⟸   XM_039101677
- Peptide Label: isoform X1
- UniProtKB: Q63396 (UniProtKB/Swiss-Prot),   Q5M805 (UniProtKB/Swiss-Prot),   A6KJQ6 (UniProtKB/TrEMBL),   A0A8I5ZJM1 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038957604   ⟸   XM_039101676
- Peptide Label: isoform X1
- UniProtKB: Q63396 (UniProtKB/Swiss-Prot),   Q5M805 (UniProtKB/Swiss-Prot),   A6KJQ6 (UniProtKB/TrEMBL),   A0A8I5ZJM1 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSRNOP00000092370   ⟸   ENSRNOT00000113169
RefSeq Acc Id: ENSRNOP00000077928   ⟸   ENSRNOT00000109925
RefSeq Acc Id: XP_063137342   ⟸   XM_063281272
- Peptide Label: isoform X1
- UniProtKB: Q63396 (UniProtKB/Swiss-Prot),   Q5M805 (UniProtKB/Swiss-Prot),   A0A8I5ZJM1 (UniProtKB/TrEMBL),   A6KJQ6 (UniProtKB/TrEMBL)
Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q63396-F1-model_v2 AlphaFold Q63396 1-127 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13691193
Promoter ID:EPDNEW_R1717
Type:multiple initiation site
Name:Sub1_1
Description:SUB1 homolog, transcriptional regulator
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0262,034,664 - 62,034,724EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:621582 AgrOrtholog
BioCyc Gene G2FUF-54052 BioCyc
Ensembl Genes ENSRNOG00000050563 Ensembl, UniProtKB/TrEMBL
  ENSRNOG00000067555 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSRNOG00055026022 UniProtKB/Swiss-Prot
  ENSRNOG00060024335 UniProtKB/Swiss-Prot
  ENSRNOG00065021147 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000074446.3 UniProtKB/TrEMBL
  ENSRNOT00000109925.1 UniProtKB/TrEMBL
  ENSRNOT00000113169.1 UniProtKB/Swiss-Prot
  ENSRNOT00055044928 UniProtKB/Swiss-Prot
  ENSRNOT00060042146 UniProtKB/Swiss-Prot
  ENSRNOT00065035957 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7368325 IMAGE-MGC_LOAD
InterPro PC4 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ssDNA-bd_transcriptional_reg UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Sub1/Tcp4-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:192269 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE MGC:109653 IMAGE-MGC_LOAD
NCBI Gene 192269 ENTREZGENE
PANTHER ACTIVATED RNA POLYMERASE II TRANSCRIPTIONAL COACTIVATOR P15 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR13215 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam PC4 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Sub1 PhenoGen
RatGTEx ENSRNOG00000050563 RatGTEx
  ENSRNOG00000067555 RatGTEx
  ENSRNOG00055026022 RatGTEx
  ENSRNOG00060024335 RatGTEx
  ENSRNOG00065021147 RatGTEx
Superfamily-SCOP SSF54447 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I5ZJM1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8L2R063_RAT UniProtKB/TrEMBL
  A6KJQ6 ENTREZGENE, UniProtKB/TrEMBL
  Q5M805 ENTREZGENE
  Q63396 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary Q5M805 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-08-05 Sub1  SUB1 regulator of transcription  Sub1  SUB1 homolog, transcriptional regulator  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2015-10-01 Sub1  SUB1 homolog, transcriptional regulator  Sub1  SUB1 homolog (S. cerevisiae)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Sub1  SUB1 homolog (S. cerevisiae)  Rpo2tc1  RNA polymerase II transcriptional coactivator  Symbol and Name updated 1299863 APPROVED
2005-01-20 Rpo2tc1  RNA polymerase II transcriptional coactivator  Loc192269  pR-ET2 encoded oncodevelopmental protein  Symbol and Name updated 1299863 APPROVED
2002-08-07 Loc192269  pR-ET2 encoded oncodevelopmental protein      Symbol and Name status set to provisional 70820 PROVISIONAL