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Gene: Il2rg (interleukin 2 receptor subunit gamma) Rattus norvegicus
Symbol: Il2rg
Name: interleukin 2 receptor subunit gamma
Description: Predicted to have interleukin-15 receptor activity and interleukin-2 binding activity. Predicted to be involved in several processes, including interleukin-15-mediated signaling pathway; positive regulation of lymphocyte differentiation; and positive regulation of phagocytosis. Predicted to localize to external side of plasma membrane and receptor complex. Used to study combined T cell and B cell immunodeficiency. Human ortholog(s) of this gene implicated in X-linked severe combined immunodeficiency; combined T cell and B cell immunodeficiency; and severe combined immunodeficiency. Orthologous to human IL2RG (interleukin 2 receptor subunit gamma); PARTICIPATES IN interleukin-12 signaling pathway; interleukin-2 signaling pathway; interleukin-4 signaling pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 4,4'-diaminodiphenylmethane; 4-hydroxycyclophosphamide.
Type: protein-coding
Also known as: Ab2-183; Cd132; cytokine receptor common subunit gamma; interleukin 2 receptor, gamma (severe combined immunodeficiency); interleukin 2 receptor, gamma chain
Homo sapiens (human) : IL2RG (interleukin 2 receptor subunit gamma)  HGNC  Alliance
Mus musculus (house mouse) : Il2rg (interleukin 2 receptor, gamma chain)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Il2rg (interleukin 2 receptor subunit gamma)
Pan paniscus (bonobo/pygmy chimpanzee) : IL2RG (interleukin 2 receptor subunit gamma)
Canis lupus familiaris (dog) : IL2RG (interleukin 2 receptor subunit gamma)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Il2rg (interleukin 2 receptor subunit gamma)
Sus scrofa (pig) : IL2RG (interleukin 2 receptor subunit gamma)
Chlorocebus sabaeus (African green monkey) : IL2RG (interleukin 2 receptor subunit gamma)
Heterocephalus glaber (naked mole-rat) : Il2rg (interleukin 2 receptor subunit gamma)
more info ...
Allele / Splice: Il2rgem2Mcwi   Il2rgem1Mcwi   Il2rgem3Mcwi   Il2rgem1Kyo   Il2rgem2Kyo   Il2rgem1Hina   Il2rgem6Kyo   Il2rgem5Kyo   Il2rgem1Iexas   Il2rgem4Kyo   Il2rgem3Kyo   Il2rgem1Ang  
Genetic Models: SD-Il2rgem1Ang TM-Il2rgem5Kyo TM-Il2rgem4Kyo F344-Il2rgem3Kyo F344-Il2rgem2Kyo F344-Il2rgem1Kyo F344-Il2rgem1Iexas W-Il2rgem1Hina TM-Prkdcem4KyoIl2rgem5Kyo F344-Prkdcem2KyoIl2rgem6Kyo SD-Rag2em3McwiIl2rgem2Mcwi SD-Il2rgem2Mcwi SS-Il2rgem1Mcwi SD-Il2rgem3Mcwi
Is Marker For: Strains:   F344-Prkdcem2KyoIl2rgem6Kyo   TM-Prkdcem4KyoIl2rgem5Kyo  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.0X71,165,378 - 71,169,078 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX71,162,585 - 71,169,865 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X72,017,856 - 72,021,516 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X89,342,055 - 89,345,715 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1X89,416,495 - 89,419,068 (-)NCBI
CeleraX66,751,239 - 66,754,899 (-)NCBICelera
Cytogenetic MapXq22NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Related Rat Strains
Genetic Models
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Il2rg
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 621466
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2020-07-07
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.