Slc25a20 (solute carrier family 25 member 20) - Rat Genome Database

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Gene: Slc25a20 (solute carrier family 25 member 20) Rattus norvegicus
Analyze
Symbol: Slc25a20
Name: solute carrier family 25 member 20
RGD ID: 621443
Description: Enables O-acyl-L-carnitine transmembrane transporter activity. Involved in carnitine transmembrane transport. Predicted to be located in mitochondrial inner membrane. Predicted to be active in mitochondrial envelope. Human ortholog(s) of this gene implicated in carnitine-acylcarnitine translocase deficiency. Orthologous to human SLC25A20 (solute carrier family 25 member 20); PARTICIPATES IN adrenoleukodystrophy pathway; carnitine-acylcarnitine translocase deficiency; fatty acid beta degradation pathway; INTERACTS WITH (R)-carnitine; 2,3,7,8-tetrachlorodibenzodioxine; 2,4,6-trinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: CAC; CACT; carnitine/acylcarnitine translocase; MGC93269; mitochondrial carnitine/acylcarnitine carrier protein; solute carrier family 25 (carnitine/acylcarnitine translocase), member 20; solute carrier family 25 (mitochondrial carnitine/acylcarnitine translocase), member 20
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88118,243,573 - 118,265,027 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl8118,243,519 - 118,265,027 (+)EnsemblGRCr8
mRatBN7.28109,365,056 - 109,386,512 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl8109,365,002 - 109,386,512 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx8114,983,063 - 115,004,624 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.08113,182,398 - 113,203,797 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.08111,025,038 - 111,046,601 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.08117,455,308 - 117,476,762 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8117,455,262 - 117,476,734 (+)Ensemblrn6Rnor6.0
Rnor_5.08116,800,146 - 116,821,558 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.48113,715,211 - 113,737,063 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera8108,660,802 - 108,681,758 (+)NCBICelera
RGSC_v3.18113,734,665 - 113,756,518 (+)NCBI
Cytogenetic Map8q32NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
(R)-carnitine  (EXP)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (ISO)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-trinitrotoluene  (EXP)
3,3',4,4'-tetrachlorobiphenyl  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
acetamide  (EXP)
aconitine  (EXP)
aflatoxin B1  (EXP)
Aflatoxin B2 alpha  (ISO)
all-trans-retinoic acid  (ISO)
amiodarone  (EXP)
ammonium chloride  (EXP)
ampicillin  (EXP)
aristolochic acid A  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
benzo[a]pyrene  (ISO)
benzo[e]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (EXP,ISO)
bisphenol A  (EXP,ISO)
bisphenol AF  (ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
buspirone  (EXP)
Butylbenzyl phthalate  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
calcitriol  (ISO)
carbon nanotube  (ISO)
cefalotin  (EXP)
cefazolin  (EXP)
cefonicid  (EXP)
chloroacetaldehyde  (ISO)
chromium(6+)  (ISO)
cidofovir anhydrous  (ISO)
ciprofibrate  (EXP)
cisplatin  (ISO)
clodronic acid  (ISO)
clofibrate  (EXP,ISO)
Clofop  (ISO)
copper(II) sulfate  (ISO)
corn oil  (ISO)
cyclosporin A  (EXP,ISO)
dexamethasone  (ISO)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (EXP)
dichloroacetic acid  (ISO)
dicrotophos  (ISO)
dioxygen  (ISO)
diquat  (ISO)
dithioerythritol  (EXP,ISO)
diuron  (ISO)
dorsomorphin  (ISO)
doxorubicin  (EXP)
epoxiconazole  (ISO)
eugenol  (EXP)
farnesol  (ISO)
fenofibrate  (EXP,ISO)
finasteride  (EXP)
flutamide  (ISO)
folic acid  (ISO)
FR900359  (ISO)
glutathione  (ISO)
glycidyl methacrylate  (ISO)
GSK-J4  (ISO)
GW 4064  (ISO)
GW 7647  (ISO)
hexadecanoic acid  (EXP)
hydrogen peroxide  (EXP)
ibuprofen  (EXP)
ifosfamide  (ISO)
inulin  (ISO)
isoprenaline  (EXP)
ketoconazole  (EXP)
L-cysteine  (EXP)
lamivudine  (ISO)
leflunomide  (EXP)
lenvatinib  (EXP,ISO)
lipopolysaccharide  (ISO)
mercury dichloride  (ISO)
metformin  (EXP,ISO)
methapyrilene  (EXP,ISO)
methylmercury chloride  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
Muraglitazar  (EXP)
N,N-diethyl-m-toluamide  (EXP)
N-acetyl-L-cysteine  (EXP,ISO)
nefazodone  (EXP)
nickel atom  (ISO)
nimesulide  (EXP)
O-acetyl-L-carnitine  (EXP)
ochratoxin A  (EXP)
okadaic acid  (ISO)
oleic acid  (EXP,ISO)
paracetamol  (ISO)
PCB138  (EXP)
perfluorododecanoic acid  (ISO)
perfluorohexanesulfonic acid  (ISO)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (EXP,ISO)
perfluorooctanoic acid  (EXP,ISO)
permethrin  (EXP)
phenobarbital  (EXP)
phenylmercury acetate  (ISO)
piperacillin  (EXP)
pirinixic acid  (EXP,ISO)
potassium chromate  (ISO)
pravastatin  (ISO)
propiconazole  (ISO)
Pyridostigmine bromide  (EXP)
quercetin  (ISO)
resveratrol  (ISO)
rotenone  (EXP,ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
SB 431542  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (EXP,ISO)
streptozocin  (EXP)
sunitinib  (ISO)
Tesaglitazar  (EXP)
testosterone  (ISO)
tetrachloroethene  (ISO)
tetracycline  (ISO)
thalidomide  (ISO)
thapsigargin  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
tributylstannane  (ISO)
trichloroethene  (ISO)
trichostatin A  (ISO)
troglitazone  (EXP)
tunicamycin  (ISO)
urethane  (ISO)
valproic acid  (ISO)
zaragozic acid A  (EXP,ISO)
zidovudine  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Bacterial overexpression, purification, and reconstitution of the carnitine/acylcarnitine carrier from rat liver mitochondria. Indiveri C, etal., Biochem Biophys Res Commun. 1998 Aug 28;249(3):589-94. doi: 10.1006/bbrc.1998.9197.
4. The mitochondrial carnitine carrier protein: cDNA cloning, primary structure and comparison with other mitochondrial transport proteins. Indiveri C, etal., Biochem J 1997 Feb 1;321 ( Pt 3):713-9.
5. Site-directed mutagenesis and chemical modification of the six native cysteine residues of the rat mitochondrial carnitine carrier: implications for the role of cysteine-136. Indiveri C, etal., Biochemistry 2002 Jul 9;41(27):8649-56.
6. Identification and purification of the carnitine carrier from rat liver mitochondria. Indiveri C, etal., Biochim Biophys Acta. 1990 Oct 24;1020(1):81-6.
7. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
8. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
9. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
10. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
11. GOA pipeline RGD automated data pipeline
12. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
13. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
14. Structural insight into function and regulation of carnitine palmitoyltransferase. Rufer AC, etal., Cell Mol Life Sci. 2009 Aug;66(15):2489-501. Epub 2009 May 9.
15. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:9399886   PMID:12865426   PMID:15757911   PMID:18614015   PMID:20833797   PMID:22365929   PMID:24898781   PMID:27864727   PMID:27996060   PMID:28438511  


Genomics

Comparative Map Data
Slc25a20
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88118,243,573 - 118,265,027 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl8118,243,519 - 118,265,027 (+)EnsemblGRCr8
mRatBN7.28109,365,056 - 109,386,512 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl8109,365,002 - 109,386,512 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx8114,983,063 - 115,004,624 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.08113,182,398 - 113,203,797 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.08111,025,038 - 111,046,601 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.08117,455,308 - 117,476,762 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8117,455,262 - 117,476,734 (+)Ensemblrn6Rnor6.0
Rnor_5.08116,800,146 - 116,821,558 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.48113,715,211 - 113,737,063 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera8108,660,802 - 108,681,758 (+)NCBICelera
RGSC_v3.18113,734,665 - 113,756,518 (+)NCBI
Cytogenetic Map8q32NCBI
SLC25A20
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38348,856,926 - 48,898,882 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl348,856,926 - 48,898,904 (-)Ensemblhg38GRCh38
GRCh37348,894,359 - 48,936,315 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36348,869,368 - 48,911,333 (-)NCBIBuild 36Build 36hg18NCBI36
Build 34348,869,368 - 48,911,333NCBI
Celera348,850,594 - 48,892,435 (-)NCBICelera
Cytogenetic Map3p21.31NCBI
HuRef348,952,554 - 48,994,892 (-)NCBIHuRef
CHM1_1348,846,459 - 48,888,551 (-)NCBICHM1_1
T2T-CHM13v2.0348,885,896 - 48,927,887 (-)NCBIT2T-CHM13v2.0
Slc25a20
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399108,539,335 - 108,561,841 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl9108,539,287 - 108,561,840 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm389108,662,136 - 108,684,642 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9108,662,088 - 108,684,641 (+)Ensemblmm10GRCm38
MGSCv379108,564,429 - 108,586,972 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv369108,519,502 - 108,542,045 (+)NCBIMGSCv36mm8
Celera9108,275,033 - 108,292,081 (+)NCBICelera
Cytogenetic Map9F2NCBI
cM Map959.61NCBI
Slc25a20
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955532902,937 - 921,174 (-)Ensembl
ChiLan1.0NW_004955532902,937 - 933,675 (-)NCBIChiLan1.0ChiLan1.0
SLC25A20
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2248,836,734 - 48,878,850 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1348,841,500 - 48,883,618 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0348,782,960 - 48,824,616 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1349,863,259 - 49,901,839 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl349,863,259 - 49,901,839 (-)EnsemblpanPan2panpan1.1
SLC25A20
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12040,244,222 - 40,271,100 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2040,244,229 - 40,270,433 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha2040,161,526 - 40,188,235 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02040,601,674 - 40,627,761 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2040,601,718 - 40,755,942 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12039,967,112 - 39,993,969 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02040,370,902 - 40,397,702 (+)NCBIUNSW_CanFamBas_1.0
Slc25a20
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560263,846,541 - 63,871,412 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936529606,804 - 631,991 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936529607,035 - 631,872 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SLC25A20
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1331,523,821 - 31,553,286 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11331,523,820 - 31,553,289 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21334,777,394 - 34,804,819 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SLC25A20
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12210,261,772 - 10,300,878 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2210,261,634 - 10,300,778 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666041156,788,381 - 156,827,761 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Slc25a20
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247302,832,233 - 2,860,796 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247302,833,785 - 2,860,711 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Slc25a20
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1899,998,410 - 100,018,298 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Slc25a20
399 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:110
Count of miRNA genes:83
Interacting mature miRNAs:100
Transcripts:ENSRNOT00000027520
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2303171Bp331Blood pressure QTL 3315.570.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)8105462581132782436Rat
1549909Stresp11Stress response QTL 116.830.0019stress-related behavior trait (VT:0010451)number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)882352698127352698Rat
631210Bw3Body weight QTL35.9mesenteric fat pad mass (VT:0010427)mesenteric fat pad weight to body weight ratio (CMO:0000654)861019838121662124Rat
1554321Bmd3Bone mineral density QTL 37.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)849849908118871671Rat
9590292Uminl3Urine mineral level QTL 33.620.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)880768445125768445Rat
8694446Bw170Body weight QTL 17012.070.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)880768445125768445Rat
631650Stl6Serum triglyceride level QTL 640.0019blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)870041301121080908Rat
1581557Eae16Experimental allergic encephalomyelitis QTL 163.8nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)868690349119799881Rat
10450865Bw175Body weight QTL 1754.1total fat pad mass (VT:0015008)adipose tissue molecular composition measurement (CMO:0000484)884192326129192326Rat
738011Anxrr9Anxiety related response QTL 96.1exploratory behavior trait (VT:0010471)number of entries into a discrete space in an experimental apparatus (CMO:0000960)8102413464132782436Rat
724539Cm19Cardiac mass QTL 192.6heart mass (VT:0007028)calculated heart weight (CMO:0000073)8103375781129871912Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)855428333127966348Rat
634332Pia18Pristane induced arthritis QTL 184joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)884192326132782436Rat
2300181Bmd55Bone mineral density QTL 555.70.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)885348065130348065Rat
1300171Bp184Blood pressure QTL 1843.66arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)879394435132782436Rat
2313400Anxrr25Anxiety related response QTL 25aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)898145073122898010Rat
8694200Abfw4Abdominal fat weight QTL 49.070.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)880768445125768445Rat
8694392Bw161Body weight QTL 1618.060.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)880768445125768445Rat
61437Cia6Collagen induced arthritis QTL 6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)891340911131690273Rat

Markers in Region
RH143998  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.28109,380,452 - 109,380,561 (+)MAPPERmRatBN7.2
Rnor_6.08117,470,703 - 117,470,811NCBIRnor6.0
Rnor_5.08116,815,541 - 116,815,649UniSTSRnor5.0
RGSC_v3.48113,731,004 - 113,731,112UniSTSRGSC3.4
Celera8108,675,780 - 108,675,888UniSTS
RH 3.4 Map81115.1UniSTS
Cytogenetic Map8q32UniSTS
BE106540  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr88118,263,518 - 118,264,242 (+)Marker Load Pipeline
mRatBN7.28109,385,003 - 109,385,727 (+)MAPPERmRatBN7.2
Rnor_6.08117,475,254 - 117,475,977NCBIRnor6.0
Rnor_5.08116,820,050 - 116,820,773UniSTSRnor5.0
RGSC_v3.48113,735,555 - 113,736,278UniSTSRGSC3.4
Celera8108,680,274 - 108,680,973UniSTS
RH 3.4 Map81115.7UniSTS
Cytogenetic Map8q32UniSTS
RH136924  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.28109,386,242 - 109,386,440 (+)MAPPERmRatBN7.2
Rnor_6.08117,476,493 - 117,476,690NCBIRnor6.0
Rnor_5.08116,821,289 - 116,821,486UniSTSRnor5.0
RGSC_v3.48113,736,794 - 113,736,991UniSTSRGSC3.4
Celera8108,681,489 - 108,681,686UniSTS
Cytogenetic Map8q32UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 164 91 90 59 92 59 6 356 192 11 143 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000027520   ⟹   ENSRNOP00000027520
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl8118,243,519 - 118,265,027 (+)Ensembl
mRatBN7.2 Ensembl8109,365,002 - 109,386,512 (+)Ensembl
Rnor_6.0 Ensembl8117,455,262 - 117,476,734 (+)Ensembl
RefSeq Acc Id: NM_053965   ⟹   NP_446417
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88118,243,573 - 118,265,027 (+)NCBI
mRatBN7.28109,365,056 - 109,386,512 (+)NCBI
Rnor_6.08117,455,308 - 117,476,762 (+)NCBI
Rnor_5.08116,800,146 - 116,821,558 (+)NCBI
RGSC_v3.48113,715,211 - 113,737,063 (+)RGD
Celera8108,660,802 - 108,681,758 (+)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_446417 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH81749 (Get FASTA)   NCBI Sequence Viewer  
  CAA66410 (Get FASTA)   NCBI Sequence Viewer  
  EDL77151 (Get FASTA)   NCBI Sequence Viewer  
  EDL77152 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000027520
GenBank Protein P97521 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_446417   ⟸   NM_053965
- UniProtKB: P97521 (UniProtKB/Swiss-Prot),   Q66HP8 (UniProtKB/TrEMBL),   A6I375 (UniProtKB/TrEMBL),   F7F1T4 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000027520   ⟸   ENSRNOT00000027520

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P97521-F1-model_v2 AlphaFold P97521 1-301 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13696313
Promoter ID:EPDNEW_R6838
Type:initiation region
Name:Slc25a20_1
Description:solute carrier family 25 member 20
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R6839  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.08117,455,286 - 117,455,346EPDNEW
RGD ID:13696314
Promoter ID:EPDNEW_R6839
Type:initiation region
Name:Slc25a20_2
Description:solute carrier family 25 member 20
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R6838  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.08117,455,388 - 117,455,448EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:621443 AgrOrtholog
BioCyc Gene G2FUF-29121 BioCyc
Ensembl Genes ENSRNOG00000020288 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000027520 ENTREZGENE
Gene3D-CATH 1.50.40.10 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7134670 IMAGE-MGC_LOAD
InterPro Mitochondrial_Carrier UniProtKB/Swiss-Prot
  Mitochondrial_sb/sol_carrier UniProtKB/Swiss-Prot
  Mt_carrier_dom_sf UniProtKB/Swiss-Prot
MGC_CLONE MGC:93269 IMAGE-MGC_LOAD
NCBI Gene 117035 ENTREZGENE
PANTHER MITOCHONDRIAL BASIC AMINO ACIDS TRANSPORTER-RELATED UniProtKB/Swiss-Prot
  MITOCHONDRIAL CARNITINE/ACYLCARNITINE CARRIER PROTEIN UniProtKB/Swiss-Prot
Pfam Mito_carr UniProtKB/Swiss-Prot
PhenoGen Slc25a20 PhenoGen
PROSITE SOLCAR UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000020288 RatGTEx
Superfamily-SCOP SSF103506 UniProtKB/Swiss-Prot
UniProt A6I375 ENTREZGENE, UniProtKB/TrEMBL
  A6I376_RAT UniProtKB/TrEMBL
  F7F1T4 ENTREZGENE, UniProtKB/TrEMBL
  MCAT_RAT UniProtKB/Swiss-Prot, ENTREZGENE
  Q66HP8 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-03-09 Slc25a20  solute carrier family 25 member 20  Slc25a20  solute carrier family 25 (carnitine/acylcarnitine translocase), member 20  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-09-19 Slc25a20  solute carrier family 25 (carnitine/acylcarnitine translocase), member 20  Slc25a20  solute carrier family 25 (mitochondrial carnitine/acylcarnitine translocase), member 20  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Slc25a20  solute carrier family 25 (mitochondrial carnitine/acylcarnitine translocase), member 20    solute carrier family 25 (carnitine/acylcarnitine translocase), member 20  Name updated 1299863 APPROVED
2005-01-20 Slc25a20  solute carrier family 25 (carnitine/acylcarnitine translocase), member 20      Name updated 1299863 APPROVED
2002-08-07 Slc25a20  solute carrier family 25 (carnitine/acylcarnitine translocase), member 20      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_domains site-directed mutagenesis show that none of the native cysteines is essential for the transport mechanism 730058
gene_product member of the mitochondrial carrier family 730031
gene_protein protein contains 301 aa residues 730031