Atp5po (ATP synthase peripheral stalk subunit OSCP) - Rat Genome Database

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Gene: Atp5po (ATP synthase peripheral stalk subunit OSCP) Rattus norvegicus
Analyze
Symbol: Atp5po
Name: ATP synthase peripheral stalk subunit OSCP
RGD ID: 621379
Description: Enables estradiol binding activity. Contributes to ATP hydrolysis activity. Involved in cellular response to cAMP and cellular response to cytokine stimulus. Located in cell surface. Part of proton-transporting ATP synthase complex. Biomarker of hypothyroidism. Human ortholog(s) of this gene implicated in mitochondrial complex V (ATP synthase) deficiency nuclear type 7. Orthologous to human ATP5PO (ATP synthase peripheral stalk subunit OSCP); PARTICIPATES IN Alzheimer's disease pathway; Huntington's disease pathway; oxidative phosphorylation pathway; INTERACTS WITH 17beta-estradiol; 2,2,2-tetramine; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: ATP synthase peripheral stalk subunit OSCP, mitochondrial; ATP synthase subunit O, mitochondrial; ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit; ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit (oligomycin sensitivity conferring protein); Atp5o; Atpo; MGC72688; oligomycin sensitivity conferral protein; Oscp; sperm flagella protein 4
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81144,651,171 - 44,657,483 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1144,651,173 - 44,657,520 (-)EnsemblGRCr8
mRatBN7.21131,165,218 - 31,171,530 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1131,165,217 - 31,171,592 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1139,859,129 - 39,865,430 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01132,530,562 - 32,536,864 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01131,693,130 - 31,699,440 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01132,081,606 - 32,087,918 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1132,081,574 - 32,088,002 (-)Ensemblrn6Rnor6.0
Rnor_5.01135,685,316 - 35,691,628 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41131,914,320 - 31,920,632 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1130,824,784 - 30,831,095 (-)NCBICelera
RGSC_v3.11131,953,218 - 31,959,531 (-)NCBI
Cytogenetic Map11q11NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-dexrazoxane  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP)
2,2,2-tetramine  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,6-dimethoxyphenol  (ISO)
3H-1,2-dithiole-3-thione  (EXP)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (ISO)
5-fluorouracil  (ISO)
5-formyltetrahydrofolic acid  (ISO)
6-propyl-2-thiouracil  (EXP)
amitrole  (EXP)
ammonium chloride  (EXP)
antirheumatic drug  (ISO)
arsenite(3-)  (ISO)
atrazine  (EXP,ISO)
benzo[a]pyrene  (ISO)
benzo[e]pyrene  (ISO)
beta-lapachone  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol AF  (ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
bleomycin A2  (ISO)
Brodifacoum  (EXP)
cadmium dichloride  (EXP)
cannabidiol  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chloropicrin  (ISO)
chlorpyrifos  (ISO)
cisplatin  (EXP)
clobetasol  (ISO)
clofibrate  (EXP)
clofibric acid  (EXP)
copper atom  (EXP)
copper(0)  (EXP)
copper(II) sulfate  (ISO)
corosolic acid  (ISO)
Cuprizon  (ISO)
cyclosporin A  (ISO)
dibutyl phthalate  (EXP)
dihydroartemisinin  (ISO)
doxorubicin  (ISO)
etoposide  (ISO)
flavonoids  (EXP)
flutamide  (EXP,ISO)
folic acid  (ISO)
furfural  (ISO)
genistein  (EXP)
gentamycin  (EXP)
irinotecan  (ISO)
isoniazide  (ISO)
isoprenaline  (EXP)
ivermectin  (ISO)
josamycin  (ISO)
ketoconazole  (EXP)
lamivudine  (ISO)
lead(0)  (ISO)
melittin  (ISO)
menadione  (ISO)
methapyrilene  (ISO)
methimazole  (EXP)
N-nitrosodiethylamine  (EXP)
Nonylphenol  (EXP)
osimertinib  (EXP)
paracetamol  (ISO)
paraquat  (ISO)
perfluorooctane-1-sulfonic acid  (EXP,ISO)
phenobarbital  (EXP)
picrotoxin  (EXP)
resveratrol  (ISO)
rotenone  (ISO)
sarin  (ISO)
sodium arsenite  (EXP,ISO)
sodium chloride  (ISO)
Soman  (EXP)
streptozocin  (EXP)
sulfadimethoxine  (EXP)
tamoxifen  (ISO)
thioacetamide  (EXP)
thiram  (ISO)
tolcapone  (EXP)
triphenyl phosphate  (ISO)
tungsten  (ISO)
valproic acid  (ISO)
vanadium atom  (ISO)
vanadium(0)  (ISO)
vinclozolin  (EXP)
zidovudine  (ISO)
zinc atom  (EXP)
zinc(0)  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Hypothyroidism leads to a decreased expression of mitochondrial F0F1-ATP synthase in rat liver. null
2. Systematic Analysis of the Expression of the Mitochondrial ATP Synthase (Complex V) Subunits in Clear Cell Renal Cell Carcinoma. Brüggemann M, etal., Transl Oncol. 2017 Aug;10(4):661-668. doi: 10.1016/j.tranon.2017.06.002. Epub 2017 Jun 30.
3. F1FO ATP Synthase Is Expressed at the Surface of Embryonic Rat Heart-Derived H9c2 Cells and Is Affected by Cardiac-Like Differentiation. Comelli M, etal., J Cell Biochem. 2016 Feb;117(2):470-82. doi: 10.1002/jcb.25295.
4. cAMP regulates the functional activity, coupling efficiency and structural organization of mammalian FOF1 ATP synthase. De Rasmo D, etal., Biochim Biophys Acta. 2016 Apr;1857(4):350-8. doi: 10.1016/j.bbabio.2016.01.006. Epub 2016 Jan 13.
5. Cyclophilin D deficiency attenuates mitochondrial F1Fo ATP synthase dysfunction via OSCP in Alzheimer's disease. Gauba E, etal., Neurobiol Dis. 2019 Jan;121:138-147. doi: 10.1016/j.nbd.2018.09.020. Epub 2018 Sep 26.
6. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
7. The oligomycin sensitivity conferring protein of rat liver mitochondrial ATP synthase: arginine 94 is important for the binding of OSCP to F1. Golden TR and Pedersen PL, Biochemistry. 1998 Sep 29;37(39):13871-81.
8. Molecular cloning and sequence of cDNAs for the import precursors of oligomycin sensitivity conferring protein, ATPase inhibitor protein, and subunit c of H(+)-ATP synthase in rat mitochondria. Higuti T, etal., Biochim Biophys Acta 1993 Mar 20;1172(3):311-4.
9. TNF-like weak inducer of apoptosis aggravates left ventricular dysfunction after myocardial infarction in mice. Jarr KU, etal., Mediators Inflamm. 2014;2014:131950. doi: 10.1155/2014/131950. Epub 2014 Feb 20.
10. KEGG: Kyoto Encyclopedia of Genes and Genomes KEGG
11. Mitochondrial F(0)F(1) ATP synthase. Subunit regions on the F1 motor shielded by F(0), Functional significance, and evidence for an involvement of the unique F(0) subunit F(6). Ko YH, etal., J Biol Chem. 2000 Oct 20;275(42):32931-9.
12. Structural and functional characterization of F(o)F(1)-ATP synthase on the extracellular surface of rat hepatocytes. Mangiullo R, etal., Biochim Biophys Acta. 2008 Oct;1777(10):1326-35. doi: 10.1016/j.bbabio.2008.08.003. Epub 2008 Aug 15.
13. 3,5-diiodo-L-thyronine upregulates rat-liver mitochondrial F(o)F(1)-ATP synthase by GA-binding protein/nuclear respiratory factor-2. Mangiullo R, etal., Biochim Biophys Acta. 2010 Feb;1797(2):233-40. doi: 10.1016/j.bbabio.2009.10.009. Epub 2009 Oct 28.
14. Identification of two proteins associated with mammalian ATP synthase. Meyer B, etal., Mol Cell Proteomics. 2007 Oct;6(10):1690-9. Epub 2007 Jun 17.
15. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
16. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
17. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
18. The functional expression of a rat cDNA encoding OSCP in the yeast Saccharomyces cerevisiae. Prescott M, etal., Biochem Biophys Res Commun. 1995 Feb 27;207(3):943-9. doi: 10.1006/bbrc.1995.1276.
19. GOA pipeline RGD automated data pipeline
20. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
21. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
22. PFOS prenatal exposure induce mitochondrial injury and gene expression change in hearts of weaned SD rats. Xia W, etal., Toxicology. 2011 Mar 28;282(1-2):23-9. Epub 2011 Jan 18.
23. Purification and identification of an estrogen binding protein from rat brain: oligomycin sensitivity-conferring protein (OSCP), a subunit of mitochondrial F0F1-ATP synthase/ATPase. Zheng J and Ramirez VD, J Steroid Biochem Mol Biol 1999 Jan;68(1-2):65-75.
Additional References at PubMed
PMID:12110673   PMID:12477932   PMID:14651853   PMID:15489334   PMID:15850986   PMID:17634366   PMID:17851741   PMID:18614015   PMID:20833797   PMID:21630459   PMID:23376485   PMID:23979707  
PMID:24625528   PMID:29476059   PMID:32357304   PMID:35352799  


Genomics

Comparative Map Data
Atp5po
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81144,651,171 - 44,657,483 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1144,651,173 - 44,657,520 (-)EnsemblGRCr8
mRatBN7.21131,165,218 - 31,171,530 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1131,165,217 - 31,171,592 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1139,859,129 - 39,865,430 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01132,530,562 - 32,536,864 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01131,693,130 - 31,699,440 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01132,081,606 - 32,087,918 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1132,081,574 - 32,088,002 (-)Ensemblrn6Rnor6.0
Rnor_5.01135,685,316 - 35,691,628 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41131,914,320 - 31,920,632 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1130,824,784 - 30,831,095 (-)NCBICelera
RGSC_v3.11131,953,218 - 31,959,531 (-)NCBI
Cytogenetic Map11q11NCBI
ATP5PO
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382133,903,453 - 33,915,804 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2133,903,453 - 33,915,814 (-)Ensemblhg38GRCh38
GRCh372135,275,757 - 35,288,108 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362134,197,627 - 34,210,028 (-)NCBIBuild 36Build 36hg18NCBI36
Build 342134,197,627 - 34,210,028NCBI
Celera2120,475,343 - 20,487,744 (-)NCBICelera
Cytogenetic Map21q22.11ENTREZGENE
HuRef2120,753,820 - 20,766,232 (-)NCBIHuRef
CHM1_12134,838,231 - 34,850,633 (-)NCBICHM1_1
T2T-CHM13v2.02132,285,156 - 32,297,516 (-)NCBIT2T-CHM13v2.0
Atp5po
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391691,722,111 - 91,728,518 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1691,481,286 - 91,723,870 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm39 Ensembl1691,722,102 - 91,728,575 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381691,925,223 - 91,931,630 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1691,684,398 - 91,926,982 (-)Ensemblmm10GRCm38
GRCm38.p6 Ensembl1691,925,214 - 91,931,687 (-)Ensemblmm10GRCm38
MGSCv371691,925,468 - 91,931,875 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361691,814,082 - 91,820,489 (-)NCBIMGSCv36mm8
Celera1693,009,520 - 93,015,922 (-)NCBICelera
Cytogenetic Map16C4NCBI
cM Map1653.26NCBI
Atp5po
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540733,286,178 - 33,299,420 (-)Ensembl
ChiLan1.0NW_00495540733,288,194 - 33,298,817 (-)NCBIChiLan1.0ChiLan1.0
ATP5PO
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22230,020,947 - 30,033,488 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12124,879,371 - 24,891,885 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02120,270,442 - 20,282,865 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12133,640,394 - 33,652,891 (-)NCBIPanPan1.1PanPan1.1panPan2
ATP5PO
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13128,472,106 - 28,481,759 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3128,469,812 - 28,479,442 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.03128,677,289 - 28,686,884 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3128,677,286 - 28,686,848 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13128,543,896 - 28,553,521 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03128,558,342 - 28,567,972 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03129,057,680 - 29,067,316 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Atp5po
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440497129,013,129 - 29,023,172 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365008,444,546 - 8,456,048 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365008,444,681 - 8,454,694 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ATP5PO
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13197,509,331 - 197,519,588 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.113197,509,331 - 197,519,530 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213207,336,292 - 207,346,559 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ATP5PO
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1258,273,181 - 58,285,615 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666071777,701 - 790,247 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Atp5po
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474522,064,441 - 22,074,773 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462474522,064,438 - 22,074,753 (-)NCBIHetGla 1.0HetGla 1.0hetGla2

Variants

.
Variants in Atp5po
47 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:66
Count of miRNA genes:58
Interacting mature miRNAs:64
Transcripts:ENSRNOT00000002732
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300147Bp187Blood pressure QTL 1873.67arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)11169446234Rat
724554Iddm17Insulin dependent diabetes mellitus QTL 170.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)111897620886241447Rat
1598842Glom10Glomerulus QTL 103.4kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)11135331169Rat
8694376Bw156Body weight QTL 1562.250.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)112328045668280456Rat
10755497Bp388Blood pressure QTL 3882.76arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)111945620576331918Rat
724517Uae18Urinary albumin excretion QTL 183.7urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)111647204744285911Rat
10058952Gmadr6Adrenal mass QTL 62.290.0072adrenal gland mass (VT:0010420)both adrenal glands wet weight to body weight ratio (CMO:0002411)112295940367959403Rat
1300130Rf20Renal function QTL 204.44kidney glomerulus integrity trait (VT:0010546)kidney glomerulus diameter (CMO:0001166)112952841860324829Rat
1558659Tescar1Testicular tumor resistance QTL 13.9testis integrity trait (VT:0010572)percentage of study population developing testis tumors during a period of time (CMO:0001261)11104193166113562Rat
724563Uae10Urinary albumin excretion QTL 106urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)112767241082846715Rat
9589032Epfw10Epididymal fat weight QTL 109.290.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)112328045668280456Rat
9590313Scort20Serum corticosterone level QTL 206.510.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)112328045668280456Rat
8694424Bw162Body weight QTL 1623.80.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)112328045668280456Rat
1300110Stl7Serum triglyceride level QTL 74.64blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)112952841882566702Rat
1641927Alcrsp10Alcohol response QTL 10alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)11843667453436674Rat

Markers in Region
RH140852  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81144,651,189 - 44,651,535 (+)Marker Load Pipeline
mRatBN7.21131,165,236 - 31,165,582 (+)MAPPERmRatBN7.2
Rnor_6.01132,081,625 - 32,081,970NCBIRnor6.0
Rnor_5.01135,685,335 - 35,685,680UniSTSRnor5.0
RGSC_v3.41131,914,339 - 31,914,684UniSTSRGSC3.4
Celera1130,824,803 - 30,825,148UniSTS
Cytogenetic Map11q11UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000002732   ⟹   ENSRNOP00000002732
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1144,651,173 - 44,657,520 (-)Ensembl
mRatBN7.2 Ensembl1131,165,226 - 31,171,592 (-)Ensembl
Rnor_6.0 Ensembl1132,081,574 - 32,088,002 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000105272   ⟹   ENSRNOP00000079398
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1131,165,217 - 31,170,987 (-)Ensembl
RefSeq Acc Id: NM_138883   ⟹   NP_620238
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81144,651,171 - 44,657,483 (-)NCBI
mRatBN7.21131,165,218 - 31,171,530 (-)NCBI
Rnor_6.01132,081,606 - 32,087,918 (-)NCBI
Rnor_5.01135,685,316 - 35,691,628 (-)NCBI
RGSC_v3.41131,914,320 - 31,920,632 (-)RGD
Celera1130,824,784 - 30,831,095 (-)RGD
Sequence:
RefSeq Acc Id: NP_620238   ⟸   NM_138883
- Peptide Label: precursor
- UniProtKB: Q06647 (UniProtKB/Swiss-Prot),   A6JLH8 (UniProtKB/TrEMBL),   A0A8I5ZMM6 (UniProtKB/TrEMBL),   A6JLH9 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000002732   ⟸   ENSRNOT00000002732
Ensembl Acc Id: ENSRNOP00000079398   ⟸   ENSRNOT00000105272

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q06647-F1-model_v2 AlphaFold Q06647 1-213 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698063
Promoter ID:EPDNEW_R8588
Type:initiation region
Name:Atp5po_1
Description:ATP synthase peripheral stalk subunit OSCP
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01132,087,930 - 32,087,990EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:621379 AgrOrtholog
BioCyc Gene G2FUF-21873 BioCyc
BioCyc Pathway PWY-7980 [ATP biosynthesis] BioCyc
BioCyc Pathway Image PWY-7980 BioCyc
Ensembl Genes ENSRNOG00000001991 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000002732 ENTREZGENE
  ENSRNOT00000002732.7 UniProtKB/Swiss-Prot
Gene3D-CATH 1.10.520.20 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:6918775 IMAGE-MGC_LOAD
InterPro ATP_synth_OSCP/delta_N_sf UniProtKB/Swiss-Prot
  ATPase_OSCP/d_CS UniProtKB/Swiss-Prot
  ATPase_OSCP/dsu UniProtKB/Swiss-Prot
KEGG Report rno:192241 UniProtKB/Swiss-Prot
MGC_CLONE MGC:72688 IMAGE-MGC_LOAD
NCBI Gene 192241 ENTREZGENE
PANTHER PTHR11910 UniProtKB/Swiss-Prot
Pfam OSCP UniProtKB/Swiss-Prot
PhenoGen Atp5po PhenoGen
PRINTS ATPASEDELTA UniProtKB/Swiss-Prot
PROSITE ATPASE_DELTA UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000001991 RatGTEx
Superfamily-SCOP SSF47928 UniProtKB/Swiss-Prot
UniProt A0A8I5ZMM6 ENTREZGENE, UniProtKB/TrEMBL
  A6JLH8 ENTREZGENE, UniProtKB/TrEMBL
  A6JLH9 ENTREZGENE, UniProtKB/TrEMBL
  ATPO_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-12-01 Atp5po  ATP synthase peripheral stalk subunit OSCP  Atp5o  ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-20 Atp5o  ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit    ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit (oligomycin sensitivity conferring protein)  Name updated 1299863 APPROVED
2002-08-07 Atp5o  ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit (oligomycin sensitivity conferring protein)      Symbol and Name status set to provisional 70820 PROVISIONAL