Atp5pf (ATP synthase peripheral stalk subunit F6) - Rat Genome Database

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Gene: Atp5pf (ATP synthase peripheral stalk subunit F6) Rattus norvegicus
Analyze
Symbol: Atp5pf
Name: ATP synthase peripheral stalk subunit F6
RGD ID: 621376
Description: Contributes to ATP hydrolysis activity. Involved in several processes, including negative regulation of icosanoid secretion; positive regulation of heart rate; and response to muscle activity. Located in cell surface and extracellular space. Part of mitochondrial proton-transporting ATP synthase complex, coupling factor F(o). Used to study pulmonary hypertension. Biomarker of pulmonary hypertension. Orthologous to human ATP5PF (ATP synthase peripheral stalk subunit F6); PARTICIPATES IN forkhead class A signaling pathway; Alzheimer's disease pathway; Huntington's disease pathway; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: ATP synthase, H+ transporting, mitochondrial F0 complex, subunit F6; ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6; ATP synthase-coupling factor 6, mitochondrial; Atp5j; ATPase subunit F6; coupling factor 6; LOC102551946; uncharacterized LOC102551946
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81137,368,045 - 37,375,721 (-)NCBIGRCr8
mRatBN7.21123,881,594 - 23,889,581 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1123,881,592 - 23,889,119 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1132,587,838 - 32,594,892 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01125,288,245 - 25,295,299 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01124,476,951 - 24,484,006 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01124,286,806 - 24,294,419 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1124,286,787 - 24,294,179 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01127,914,805 - 27,918,237 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41124,316,748 - 24,323,800 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11124,316,747 - 24,323,800 (-)NCBI
Celera1123,720,789 - 23,727,843 (-)NCBICelera
Cytogenetic Map11q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Comparison of gene and protein expressions in rats residing in standard cages with those having access to an exercise wheel. Alessio HM, etal., Biomed Res Int. 2014;2014:950516. doi: 10.1155/2014/950516. Epub 2014 Feb 25.
2. Total synthesis of human and rat coupling factor-6 amide and pressor effects in the rat. Chang JK, etal., Regul Pept. 2003 May 15;113(1-3):63-9.
3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
5. Mitochondrial coupling factor 6 upregulation in hypertension-induced cardiac hypertrophy. He T, etal., Herz. 2015 Aug;40(5):783-7. doi: 10.1007/s00059-015-4301-8. Epub 2015 Apr 22.
6. cDNA cloning and sequencing for the import precursor of coupling factor 6 in H(+)-ATP synthase from rat liver mitochondria. Higuti T, etal., Biochem Biophys Res Commun 1990 Sep 28;171(3):1079-86.
7. A simple, rapid method for purification of epsilon-subunit, coupling factor 6, subunit d, and subunit e from rat liver H(+)-ATP synthase and determination of the complete amino acid sequence of epsilon-subunit. Higuti T, etal., J Biol Chem. 1992 Nov 5;267(31):22658-61.
8. KEGG: Kyoto Encyclopedia of Genes and Genomes KEGG
9. Mitochondrial F(0)F(1) ATP synthase. Subunit regions on the F1 motor shielded by F(0), Functional significance, and evidence for an involvement of the unique F(0) subunit F(6). Ko YH, etal., J Biol Chem. 2000 Oct 20;275(42):32931-9.
10. Coupling Factor 6 Is Upregulated in Monocrotaline-induced Pulmonary Arterial Hypertension in Rats. Li N, etal., Am J Med Sci. 2016 Dec;352(6):631-636. doi: 10.1016/j.amjms.2016.08.002. Epub 2016 Aug 15.
11. Identification of two proteins associated with mammalian ATP synthase. Meyer B, etal., Mol Cell Proteomics. 2007 Oct;6(10):1690-9. Epub 2007 Jun 17.
12. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
13. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
14. A novel inhibitory effect on prostacyclin synthesis of coupling factor 6 extracted from the heart of spontaneously hypertensive rats. Osanai T, etal., J Biol Chem. 1998 Nov 27;273(48):31778-83.
15. Mitochondrial coupling factor 6 as a potent endogenous vasoconstrictor. Osanai T, etal., J Clin Invest. 2001 Oct;108(7):1023-30. doi: 10.1172/JCI11076.
16. Circulating coupling factor 6 in human hypertension: role of reactive oxygen species. Osanai T, etal., J Hypertens. 2003 Dec;21(12):2323-8. doi: 10.1097/01.hjh.0000098161.70956.08.
17. Coupling factor 6-induced prostacyclin inhibition is enhanced in vascular smooth muscle cells from spontaneously hypertensive rats. Osanai T, etal., J Hypertens. 2009 Sep;27(9):1823-8. doi: 10.1097/HJH.0b013e32832d4b05.
18. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
19. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
20. Application of a discovery to targeted LC-MS proteomics approach to identify deregulated proteins associated with idiosyncratic liver toxicity in a rat model of LPS/diclofenac co-administration. Ramm S, etal., Toxicology. 2015 May 4;331:100-11. doi: 10.1016/j.tox.2015.03.004. Epub 2015 Mar 13.
21. GOA pipeline RGD automated data pipeline
22. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
23. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
24. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
25. Rat mitochondrial coupling factor 6: molecular cloning of a cDNA encoding the imported precursor. Tracer HL, etal., Gene 1992 Jul 15;116(2):291-2.
26. Lung-specific RNA interference of coupling factor 6, a novel peptide, attenuates pulmonary arterial hypertension in rats. Yin J, etal., Respir Res. 2016 Aug 4;17(1):99. doi: 10.1186/s12931-016-0409-5.
27. H(+)-ATP synthase from rat liver mitochondria. A simple, rapid purification method of the functional complex and its characterization. Yoshihara Y, etal., Biochemistry. 1991 Jul 16;30(28):6854-60.
28. Marine collagen peptides reduce endothelial cell injury in diabetic rats by inhibiting apoptosis and the expression of coupling factor 6 and microparticles. Zhu C, etal., Mol Med Rep. 2017 Oct;16(4):3947-3957. doi: 10.3892/mmr.2017.7061. Epub 2017 Jul 21.
Additional References at PubMed
PMID:12110673   PMID:12865426   PMID:14651853   PMID:15489334   PMID:18614015   PMID:20833797   PMID:22926577   PMID:25002582   PMID:29476059   PMID:35352799  


Genomics

Comparative Map Data
Atp5pf
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81137,368,045 - 37,375,721 (-)NCBIGRCr8
mRatBN7.21123,881,594 - 23,889,581 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1123,881,592 - 23,889,119 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1132,587,838 - 32,594,892 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01125,288,245 - 25,295,299 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01124,476,951 - 24,484,006 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01124,286,806 - 24,294,419 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1124,286,787 - 24,294,179 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01127,914,805 - 27,918,237 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41124,316,748 - 24,323,800 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11124,316,747 - 24,323,800 (-)NCBI
Celera1123,720,789 - 23,727,843 (-)NCBICelera
Cytogenetic Map11q11NCBI
ATP5PF
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382125,724,500 - 25,735,653 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2125,716,503 - 25,735,673 (-)EnsemblGRCh38hg38GRCh38
GRCh372127,096,811 - 27,107,964 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362126,018,662 - 26,029,836 (-)NCBINCBI36Build 36hg18NCBI36
Build 342126,018,662 - 26,029,836NCBI
Celera2112,280,206 - 12,291,380 (-)NCBICelera
Cytogenetic Map21q21.3NCBI
HuRef2112,499,927 - 12,511,003 (-)NCBIHuRef
CHM1_12126,657,444 - 26,668,586 (-)NCBICHM1_1
T2T-CHM13v2.02124,082,042 - 24,093,216 (-)NCBIT2T-CHM13v2.0
Atp5pf
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391684,624,754 - 84,632,495 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1684,624,754 - 84,632,513 (-)EnsemblGRCm39 Ensembl
GRCm381684,827,871 - 84,835,857 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1684,827,866 - 84,835,625 (-)EnsemblGRCm38mm10GRCm38
MGSCv371684,828,116 - 84,835,819 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361684,710,463 - 84,718,166 (-)NCBIMGSCv36mm8
Celera1685,033,263 - 85,040,971 (-)NCBICelera
Cytogenetic Map16C3.3NCBI
cM Map1646.92NCBI
Atp5pf
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540725,601,083 - 25,609,888 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540725,601,253 - 25,609,933 (-)NCBIChiLan1.0ChiLan1.0
ATP5PF
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22221,919,475 - 21,930,738 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12116,776,655 - 16,787,928 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02112,169,567 - 12,180,717 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12125,526,252 - 25,537,363 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2125,519,441 - 25,537,363 (-)Ensemblpanpan1.1panPan2
ATP5PF
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13121,207,080 - 21,212,220 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3121,200,337 - 21,215,975 (-)EnsemblCanFam3.1canFam3CanFam3.1
ROS_Cfam_1.03121,261,085 - 21,269,970 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3121,254,346 - 21,269,778 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13121,278,973 - 21,288,056 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03121,280,200 - 21,289,273 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03121,755,620 - 21,764,710 (-)NCBIUU_Cfam_GSD_1.0
Atp5pf
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440497121,756,733 - 21,764,531 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049366401,916,711 - 1,924,823 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ATP5PF
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13189,278,945 - 189,290,229 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113189,281,429 - 189,290,234 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213199,153,513 - 199,157,380 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ATP5PF
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1266,539,014 - 66,550,186 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl266,538,864 - 66,550,046 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605087,004,210 - 87,016,075 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Atp5pf
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474513,779,610 - 13,787,610 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474513,779,610 - 13,787,525 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Atp5pf
4 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:12
Count of miRNA genes:11
Interacting mature miRNAs:12
Transcripts:ENSRNOT00000002116
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1598842Glom10Glomerulus QTL 103.4kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)11135331169Rat
1300147Bp187Blood pressure QTL 1873.67arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)11169446234Rat
1558659Tescar1Testicular tumor resistance QTL 13.9testis integrity trait (VT:0010572)percentage of study population developing testis tumors during a period of time (CMO:0001261)11104193166113562Rat
1641927Alcrsp10Alcohol response QTL 10alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)11843667453436674Rat
2290451Scl58Serum cholesterol level QTL 583.48blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)111283104625121472Rat
724517Uae18Urinary albumin excretion QTL 183.7urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)111647204744285911Rat
1600394Edcs1Endometrial carcinoma susceptibility QTL12.90.04uterus morphology trait (VT:0001120)percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)111897620824697116Rat
724554Iddm17Insulin dependent diabetes mellitus QTL 170.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)111897620886241447Rat
10058952Gmadr6Adrenal mass QTL 62.290.0072adrenal gland mass (VT:0010420)both adrenal glands wet weight to body weight ratio (CMO:0002411)112295940367959403Rat
8694376Bw156Body weight QTL 1562.250.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)112328045668280456Rat
9590313Scort20Serum corticosterone level QTL 206.510.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)112328045668280456Rat
9589032Epfw10Epididymal fat weight QTL 109.290.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)112328045668280456Rat
8694424Bw162Body weight QTL 1623.80.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)112328045668280456Rat

Markers in Region
PMC200946P1  
Rat AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map5q36UniSTS
Cytogenetic Map11q11UniSTS
RH130478  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21123,881,659 - 23,882,218 (+)MAPPERmRatBN7.2
Rnor_6.01124,286,872 - 24,287,430NCBIRnor6.0
Rnor_5.01127,914,868 - 27,915,426UniSTSRnor5.0
RGSC_v3.41124,316,811 - 24,317,369UniSTSRGSC3.4
Celera1123,720,852 - 23,721,410UniSTS
RH 3.4 Map11102.1UniSTS
Cytogenetic Map11q11UniSTS
RH143804  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21123,885,690 - 23,885,938 (+)MAPPERmRatBN7.2
Rnor_6.01124,290,903 - 24,291,150NCBIRnor6.0
Rnor_5.01127,918,899 - 27,919,145UniSTSRnor5.0
RGSC_v3.41124,320,842 - 24,321,087UniSTSRGSC3.4
Celera1123,724,883 - 23,725,130UniSTS
RH 3.4 Map11142.28UniSTS
Cytogenetic Map11q11UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 43 57 41 19 41 8 11 74 35 41 11 8
Low
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_053602 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008768603 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017598085 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017598086 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC110471 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC059121 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473989 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ212150 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ214305 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216982 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ217271 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ217448 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ224472 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ228382 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000011 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M73030 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X54510 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSRNOT00000002116   ⟹   ENSRNOP00000002116
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1123,881,592 - 23,889,119 (-)Ensembl
Rnor_6.0 Ensembl1124,286,787 - 24,294,179 (-)Ensembl
RefSeq Acc Id: NM_053602   ⟹   NP_446054
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81137,368,047 - 37,375,101 (-)NCBI
mRatBN7.21123,881,597 - 23,888,652 (-)NCBI
Rnor_6.01124,286,809 - 24,293,863 (-)NCBI
Rnor_5.01127,914,805 - 27,918,237 (-)NCBI
RGSC_v3.41124,316,748 - 24,323,800 (-)RGD
Celera1123,720,789 - 23,727,843 (-)RGD
Sequence:
RefSeq Acc Id: XM_008768603   ⟹   XP_008766825
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81137,368,045 - 37,375,097 (-)NCBI
mRatBN7.21123,881,594 - 23,888,706 (-)NCBI
Rnor_6.01124,286,806 - 24,293,845 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017598085   ⟹   XP_017453574
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81137,368,045 - 37,375,721 (-)NCBI
mRatBN7.21123,881,595 - 23,888,777 (-)NCBI
Rnor_6.01124,286,806 - 24,293,924 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017598086   ⟹   XP_017453575
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81137,368,045 - 37,375,267 (-)NCBI
mRatBN7.21123,881,594 - 23,888,699 (-)NCBI
Rnor_6.01124,286,806 - 24,293,920 (-)NCBI
Sequence:
RefSeq Acc Id: NP_446054   ⟸   NM_053602
- Peptide Label: precursor
- UniProtKB: P21571 (UniProtKB/Swiss-Prot),   A6JL59 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008766825   ⟸   XM_008768603
- Peptide Label: isoform X2
- UniProtKB: P21571 (UniProtKB/Swiss-Prot),   A6JL59 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017453574   ⟸   XM_017598085
- Peptide Label: isoform X2
- UniProtKB: P21571 (UniProtKB/Swiss-Prot),   A6JL59 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017453575   ⟸   XM_017598086
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSRNOP00000002116   ⟸   ENSRNOT00000002116

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P21571-F1-model_v2 AlphaFold P21571 1-108 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698014
Promoter ID:EPDNEW_R8539
Type:multiple initiation site
Name:Atp5pf_1
Description:ATP synthase peripheral stalk subunit F6
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01124,293,767 - 24,293,827EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:621376 AgrOrtholog
BioCyc Gene G2FUF-22082 BioCyc
BioCyc Pathway PWY-7980 [ATP biosynthesis] BioCyc
BioCyc Pathway Image PWY-7980 BioCyc
Ensembl Genes ENSRNOG00000001551 Ensembl, UniProtKB/TrEMBL
  ENSRNOG00055002258 UniProtKB/Swiss-Prot
  ENSRNOG00055003150 UniProtKB/Swiss-Prot
  ENSRNOG00060016649 UniProtKB/Swiss-Prot
  ENSRNOG00065006280 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000002116.5 UniProtKB/TrEMBL
  ENSRNOT00055003593 UniProtKB/Swiss-Prot
  ENSRNOT00055004897 UniProtKB/Swiss-Prot
  ENSRNOT00060028495 UniProtKB/Swiss-Prot
  ENSRNOT00065009614 UniProtKB/Swiss-Prot
Gene3D-CATH 1.10.246.110 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:6919556 IMAGE-MGC_LOAD
InterPro ATP_synth_f6_mt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ATP_synth_f6_sf_mt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:94271 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE MGC:72739 IMAGE-MGC_LOAD
NCBI Gene 94271 ENTREZGENE
PANTHER ATP SYNTHASE-COUPLING FACTOR 6, MITOCHONDRIAL UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR12441 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam ATP-synt_F6 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Atp5pf PhenoGen
PIRSF ATP_synthase_coupling_factor_6 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000001551 RatGTEx
  ENSRNOG00055002258 RatGTEx
  ENSRNOG00055003150 RatGTEx
  ENSRNOG00060016649 RatGTEx
  ENSRNOG00065006280 RatGTEx
Superfamily-SCOP SSF111357 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8L2Q0A6_RAT UniProtKB/TrEMBL
  A6JL59 ENTREZGENE, UniProtKB/TrEMBL
  ATP5J_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Atp5pf  ATP synthase peripheral stalk subunit F6  LOC102551946  uncharacterized LOC102551946  Data merged from RGD:7542027 737654 PROVISIONAL
2017-12-01 Atp5pf  ATP synthase peripheral stalk subunit F6  Atp5j  ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-12-17 LOC102551946  uncharacterized LOC102551946      Symbol and Name status set to provisional 70820 PROVISIONAL
2011-12-01 Atp5j  ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6  Atp5j  ATP synthase, H+ transporting, mitochondrial F0 complex, subunit F6  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-12-14 Atp5j  ATP synthase, H+ transporting, mitochondrial F0 complex, subunit F6      Symbol and Name status set to approved 1299863 APPROVED
2002-08-07 Atp5j  ATP synthase, H+ transporting, mitochondrial F0 complex, subunit F6      Symbol and Name status set to provisional 70820 PROVISIONAL