Atp5f1b (ATP synthase F1 subunit beta) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Behavioral & Substance Use Disorder Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Atp5f1b (ATP synthase F1 subunit beta) Rattus norvegicus
Analyze
Symbol: Atp5f1b
Name: ATP synthase F1 subunit beta
RGD ID: 621368
Description: Enables several functions, including adenyl ribonucleotide binding activity; calcium ion binding activity; and proton-transporting ATP synthase activity, rotational mechanism. Contributes to ATP hydrolysis activity. Involved in several processes, including cellular response to peptide; cold acclimation; and response to 3,3',5-triiodo-L-thyronine. Located in cell surface; membrane raft; and mitochondrial inner membrane. Part of proton-transporting ATP synthase complex. Used to study obesity. Biomarker of cardiomyopathy; polycystic ovary syndrome; transient cerebral ischemia; and type 2 diabetes mellitus. Orthologous to human ATP5F1B (ATP synthase F1 subunit beta); PARTICIPATES IN electron transport chain pathway; Alzheimer's disease pathway; Huntington's disease pathway; INTERACTS WITH 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 1,3-dinitrobenzene; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: ATP synthase F(1) complex catalytic subunit beta, mitochondrial; ATP synthase subunit beta, mitochondrial; ATP synthase, H+ transporting mitochondrial F1 complex, beta subunit; ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide; Atp5b; mitochondrial ATP synthase beta subunit
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr871,100,058 - 1,106,461 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl71,099,860 - 1,106,462 (+)EnsemblGRCr8
mRatBN7.27515,454 - 521,858 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7515,460 - 567,273 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx73,274,116 - 3,280,516 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.075,150,130 - 5,156,530 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.075,451,361 - 5,457,743 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.072,504,708 - 2,511,748 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl72,504,695 - 2,511,749 (+)Ensemblrn6Rnor6.0
Rnor_5.072,484,095 - 2,490,338 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.471,376,552 - 1,383,228 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera7394,648 - 401,125 (+)NCBICelera
RGSC_v3.171,377,178 - 1,383,228 (+)NCBI
Cytogenetic Map7q11NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-dexrazoxane  (ISO)
(Z)-3-butylidenephthalide  (ISO)
1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane  (EXP,ISO)
1,2-dimethylhydrazine  (ISO)
1,3-dinitrobenzene  (EXP)
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine  (ISO)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (ISO)
2,2,2-tetramine  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (EXP,ISO)
2,6-dimethoxyphenol  (ISO)
2,6-dinitrotoluene  (EXP)
2-methyl-2-[4-(1,2,3,4-tetrahydronaphthalen-1-yl)phenoxy]propanoic acid  (EXP)
4,4'-sulfonyldiphenol  (ISO)
5-aza-2'-deoxycytidine  (ISO)
7,12-dimethyltetraphene  (EXP,ISO)
acrolein  (ISO)
actinomycin D  (ISO)
aflatoxin B1  (ISO)
amiodarone  (EXP)
ammonium chloride  (EXP)
aniline  (EXP)
aristolochic acid A  (ISO)
Aroclor 1254  (EXP)
arsane  (EXP,ISO)
arsenic atom  (EXP,ISO)
atrazine  (ISO)
beta-naphthoflavone  (EXP)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol AF  (ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
bleomycin A2  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
capsaicin  (ISO)
captan  (ISO)
carbon nanotube  (ISO)
chloropicrin  (ISO)
choline  (ISO)
chromium trinitrate  (ISO)
cisplatin  (ISO)
clobetasol  (ISO)
clofibrate  (EXP)
clozapine  (EXP)
cocaine  (ISO)
copper atom  (EXP)
copper(0)  (EXP)
copper(II) sulfate  (ISO)
cyclosporin A  (ISO)
dexamethasone  (ISO)
diclofenac  (EXP)
dicyclanil  (ISO)
diethyl maleate  (EXP)
dioxygen  (ISO)
diuron  (EXP)
doxorubicin  (ISO)
enzyme inhibitor  (ISO)
ethanol  (ISO)
fenpyroximate  (ISO)
flavonoids  (EXP)
folic acid  (ISO)
folpet  (ISO)
fulvestrant  (ISO)
furan  (EXP)
furfural  (ISO)
glyphosate  (EXP,ISO)
gold atom  (ISO)
gold(0)  (ISO)
hyaluronic acid  (EXP)
hydrogen peroxide  (EXP,ISO)
imisopasem manganese  (EXP)
isoflavones  (EXP)
isoniazide  (ISO)
ivermectin  (ISO)
josamycin  (ISO)
L-ascorbic acid  (ISO)
L-methionine  (ISO)
lead(0)  (ISO)
lipopolysaccharide  (ISO)
lithium atom  (EXP)
lithium hydride  (EXP)
methamphetamine  (EXP)
methapyrilene  (EXP)
methoxychlor  (EXP)
mitoxantrone  (ISO)
N,N-diethyl-m-toluamide  (EXP)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (ISO)
N-nitrosodiethylamine  (EXP)
N-nitrosomorpholine  (EXP)
nafenopin  (EXP)
naphthalene  (ISO)
nicotinic acid  (ISO)
nitric oxide  (ISO)
Nonylphenol  (EXP)
Nutlin-3  (ISO)
ochratoxin A  (ISO)
osimertinib  (EXP)
oxybenzone  (EXP)
paracetamol  (ISO)
paraoxon  (ISO)
perfluorooctanoic acid  (ISO)
permethrin  (EXP)
phenethyl isothiocyanate  (ISO)
PhIP  (EXP)
pioglitazone  (ISO)
piperonyl butoxide  (EXP)
potassium chromate  (ISO)
potassium dichromate  (ISO)
procymidone  (ISO)
progesterone  (EXP)
promethazine  (EXP)
Pyridostigmine bromide  (EXP)
quercetin  (ISO)
rotenone  (EXP,ISO)
S-butyl-DL-homocysteine (S,R)-sulfoximine  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
sodium chloride  (ISO)
sodium fluoride  (ISO)
sodium nitrate  (ISO)
streptozocin  (EXP)
sulforaphane  (ISO)
T-2 toxin  (EXP)
tamoxifen  (EXP,ISO)
tanespimycin  (ISO)
testosterone  (ISO)
thioacetamide  (EXP)
thiram  (ISO)
titanium dioxide  (ISO)
tolcapone  (EXP)
toluene  (EXP)
trichostatin A  (ISO)
trimellitic anhydride  (ISO)
triphenyl phosphate  (ISO)
triptonide  (ISO)
troglitazone  (ISO)
valproic acid  (ISO)
vanadium atom  (ISO)
vanadium(0)  (ISO)
vitamin E  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. ATP synthase subunit c expression: physiological regulation of the P1 and P2 genes. Andersson U, etal., Biochem J. 1997 Apr 15;323 ( Pt 2):379-85.
2. Mitochondrial ATP synthase. Quaternary structure of the F1 moiety at 3.6 A determined by x-ray diffraction analysis. Bianchet M, etal., J Biol Chem. 1991 Nov 5;266(31):21197-201.
3. The 2.8-A structure of rat liver F1-ATPase: configuration of a critical intermediate in ATP synthesis/hydrolysis. Bianchet MA, etal., Proc Natl Acad Sci U S A. 1998 Sep 15;95(19):11065-70. doi: 10.1073/pnas.95.19.11065.
4. Quantitative neuroproteomics of an in vivo rodent model of focal cerebral ischemia/reperfusion injury reveals a temporal regulation of novel pathophysiological molecular markers. Datta A, etal., J Proteome Res. 2011 Nov 4;10(11):5199-213. doi: 10.1021/pr200673y. Epub 2011 Oct 20.
5. Beta subunit of rat liver mitochondrial ATP synthase: cDNA cloning, amino acid sequence, expression in Escherichia coli, and structural relationship to adenylate kinase. Garboczi DN, etal., Biochemistry 1988 Jan 26;27(2):553-60.
6. Mitochondrial ATP synthase. Overexpression in Escherichia coli of a rat liver beta subunit peptide and its interaction with adenine nucleotides. Garboczi DN, etal., J Biol Chem. 1988 Oct 25;263(30):15694-8.
7. Rat liver mitochondrial ATP synthase. Effects of mutations in the glycine-rich region of a beta subunit peptide on its interaction with adenine nucleotides. Garboczi DN, etal., J Biol Chem. 1990 Aug 25;265(24):14632-7.
8. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
9. Detection of differential proteomes associated with the development of type 2 diabetes in the Zucker rat model using the iTRAQ technique. Han D, etal., J Proteome Res. 2011 Feb 4;10(2):564-77. doi: 10.1021/pr100759a. Epub 2010 Dec 20.
10. Mitochondrial ATP synthase F1-beta-subunit is a calcium-binding protein. Hubbard MJ and McHugh NJ, FEBS Lett. 1996 Aug 12;391(3):323-9.
11. KEGG: Kyoto Encyclopedia of Genes and Genomes KEGG
12. Mitochondrial F(0)F(1) ATP synthase. Subunit regions on the F1 motor shielded by F(0), Functional significance, and evidence for an involvement of the unique F(0) subunit F(6). Ko YH, etal., J Biol Chem. 2000 Oct 20;275(42):32931-9.
13. Proteomic characterisation of neuronal sphingolipid-cholesterol microdomains: role in plasminogen activation. Ledesma MD, etal., Brain Res. 2003 Oct 10;987(1):107-16.
14. ATP synthase ß-subunit abnormality in pancreas islets of rats with polycystic ovary syndrome and type 2 diabetes mellitus. Li W, etal., J Huazhong Univ Sci Technolog Med Sci. 2017 Apr;37(2):210-216. doi: 10.1007/s11596-017-1717-9. Epub 2017 Apr 11.
15. [Screening of differentially expressed genes in rats with cardiomyopathy after bone marrow mesenchymal stem cell transplantation]. Li Y, etal., Zhonghua Er Ke Za Zhi. 2006 Oct;44(10):787-91.
16. Translational regulation of mitochondrial differentiation in neonatal rat liver. Specific increase in the translational efficiency of the nuclear-encoded mitochondrial beta-F1-ATPase mRNA. Luis AM, etal., J Biol Chem. 1993 Jan 25;268(3):1868-75.
17. Ectopic beta-chain of ATP synthase is an apolipoprotein A-I receptor in hepatic HDL endocytosis. Martinez LO, etal., Nature 2003 Jan 2;421(6918):75-9.
18. Identification of two proteins associated with mammalian ATP synthase. Meyer B, etal., Mol Cell Proteomics. 2007 Oct;6(10):1690-9. Epub 2007 Jun 17.
19. Pharmacological inhibition of galectin-1 by lactulose alleviates weight gain in diet-induced obese rats. Mukherjee R and Yun JW, Life Sci. 2016 Mar 1;148:112-7. doi: 10.1016/j.lfs.2016.02.018. Epub 2016 Feb 13.
20. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
21. Coupling factor 6 enhances Src-mediated responsiveness to angiotensin II in resistance arterioles and cells. Osanai T, etal., Cardiovasc Res. 2009 Mar 1;81(4):780-7. doi: 10.1093/cvr/cvn356. Epub 2008 Dec 22.
22. Mitochondrial ATP synthase: dramatic Mg2+-induced alterations in the structure and function of the F1-ATPase moiety. Pedersen PL, etal., Biochemistry. 1987 Dec 29;26(26):8631-7.
23. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
24. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
25. Overdose Intake of Curcumin Initiates the Unbalanced State of Bodies. Qiu P, etal., J Agric Food Chem. 2016 Apr 6;64(13):2765-71. doi: 10.1021/acs.jafc.6b00053. Epub 2016 Mar 25.
26. Application of a discovery to targeted LC-MS proteomics approach to identify deregulated proteins associated with idiosyncratic liver toxicity in a rat model of LPS/diclofenac co-administration. Ramm S, etal., Toxicology. 2015 May 4;331:100-11. doi: 10.1016/j.tox.2015.03.004. Epub 2015 Mar 13.
27. GOA pipeline RGD automated data pipeline
28. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
29. Proteomic characterization of early changes induced by triiodothyronine in rat liver. Severino V, etal., J Proteome Res. 2011 Jul 1;10(7):3212-24. Epub 2011 Jun 1.
30. Proteomic Analysis of One-carbon Metabolism-related Marker in Liver of Rat Offspring. You YA, etal., Mol Cell Proteomics. 2015 Nov;14(11):2901-9. doi: 10.1074/mcp.M114.046888. Epub 2015 Sep 4.
31. Proteome analysis of rat pancreatic acinar cells: implication for cerulein-induced acute pancreatitis. Yu JH, etal., Proteomics. 2003 Dec;3(12):2446-53. doi: 10.1002/pmic.200300545.
32. Telmisartan improves kidney function through inhibition of the oxidative phosphorylation pathway in diabetic rats. Zhang Q, etal., J Mol Endocrinol. 2012 Jun 26;49(1):35-46. doi: 10.1530/JME-12-0020. Print 2012 Aug.
33. Changes in the brain mitochondrial proteome of male Sprague-Dawley rats treated with manganese chloride. Zhang S, etal., Toxicol Appl Pharmacol. 2005 Jan 1;202(1):13-7.
Additional References at PubMed
PMID:2522775   PMID:2531579   PMID:2870059   PMID:2907347   PMID:8006588   PMID:10077593   PMID:12110673   PMID:12477932   PMID:12865426   PMID:14651853   PMID:14673794   PMID:15489334  
PMID:15572201   PMID:16210410   PMID:16751257   PMID:16854843   PMID:17303654   PMID:17510399   PMID:17612527   PMID:17634366   PMID:17643490   PMID:17675573   PMID:17709438   PMID:18063578  
PMID:18510804   PMID:18614015   PMID:19056867   PMID:19199708   PMID:19808025   PMID:19946888   PMID:20458337   PMID:20833797   PMID:21106936   PMID:21630459   PMID:21926988   PMID:22082260  
PMID:23106098   PMID:23376485   PMID:23533145   PMID:23979707   PMID:24042457   PMID:24625528   PMID:25931508   PMID:26316108   PMID:26767982   PMID:26769832   PMID:29476059   PMID:29581031  
PMID:29867124   PMID:30552345   PMID:32357304   PMID:35352799  


Genomics

Comparative Map Data
Atp5f1b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr871,100,058 - 1,106,461 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl71,099,860 - 1,106,462 (+)EnsemblGRCr8
mRatBN7.27515,454 - 521,858 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl7515,460 - 567,273 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx73,274,116 - 3,280,516 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.075,150,130 - 5,156,530 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.075,451,361 - 5,457,743 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.072,504,708 - 2,511,748 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl72,504,695 - 2,511,749 (+)Ensemblrn6Rnor6.0
Rnor_5.072,484,095 - 2,490,338 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.471,376,552 - 1,383,228 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera7394,648 - 401,125 (+)NCBICelera
RGSC_v3.171,377,178 - 1,383,228 (+)NCBI
Cytogenetic Map7q11NCBI
ATP5F1B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381256,638,175 - 56,645,984 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1256,638,175 - 56,645,984 (-)Ensemblhg38GRCh38
GRCh371257,031,959 - 57,039,768 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361255,318,226 - 55,326,119 (-)NCBIBuild 36Build 36hg18NCBI36
Build 341255,318,227 - 55,326,119NCBI
Celera1256,683,671 - 56,691,564 (-)NCBICelera
Cytogenetic Map12q13.3NCBI
HuRef1254,071,237 - 54,079,130 (-)NCBIHuRef
CHM1_11256,999,492 - 57,007,379 (-)NCBICHM1_1
T2T-CHM13v2.01256,606,172 - 56,613,970 (-)NCBIT2T-CHM13v2.0
Atp5f1b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3910127,919,176 - 127,926,257 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl10127,919,142 - 127,926,260 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm3810128,083,307 - 128,090,388 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl10128,083,273 - 128,090,391 (+)Ensemblmm10GRCm38
MGSCv3710127,520,363 - 127,527,444 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv3610127,486,256 - 127,493,337 (+)NCBIMGSCv36mm8
Celera10130,478,043 - 130,485,124 (+)NCBICelera
Cytogenetic Map10D3NCBI
cM Map1076.39NCBI
Atp5f1b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554584,186,461 - 4,195,494 (-)Ensembl
ChiLan1.0NW_0049554584,188,167 - 4,195,575 (-)NCBIChiLan1.0ChiLan1.0
ATP5F1B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21037,680,429 - 37,689,113 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11237,677,947 - 37,685,879 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01232,264,570 - 32,272,419 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11232,519,749 - 32,527,753 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1232,519,749 - 32,527,753 (+)EnsemblpanPan2panpan1.1
ATP5F1B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.110870,405 - 876,937 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl10870,392 - 909,161 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha10933,592 - 940,127 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.010879,724 - 886,261 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl10879,724 - 919,087 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.110856,580 - 863,114 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0101,099,743 - 1,106,277 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0101,223,513 - 1,230,049 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Atp5f1b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494557,911,328 - 57,918,999 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936646951,009 - 959,516 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936646951,236 - 958,907 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ATP5F1B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl521,984,580 - 21,992,407 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1521,984,750 - 21,992,393 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2523,659,081 - 23,666,726 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ATP5F1B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11152,587,608 - 52,600,057 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1152,587,143 - 52,600,756 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666037193,380,244 - 193,389,154 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Atp5f1b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462480211,399,474 - 11,409,700 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462480211,400,288 - 11,408,785 (+)NCBIHetGla 1.0HetGla 1.0hetGla2

Variants

.
Variants in Atp5f1b
22 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:37
Count of miRNA genes:35
Interacting mature miRNAs:37
Transcripts:ENSRNOT00000003965
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
61410Bw19Body weight QTL 196.20.001body mass (VT:0001259)body weight (CMO:0000012)7144782185Rat
2317047Wbc4White blood cell count QTL 40.01leukocyte quantity (VT:0000217)white blood cell count (CMO:0000027)7135342956Rat
2298550Neuinf6Neuroinflammation QTL 63.3nervous system integrity trait (VT:0010566)spinal cord RT1-B protein level (CMO:0002132)7127829089Rat
631503Bp102Blood pressure QTL 1021.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7144822433Rat
724560Plsm3Polydactyly-luxate syndrome (PLS) morphotypes QTL 30.0003tibia length (VT:0004357)tibia length (CMO:0000450)7134000259Rat
9590142Scort5Serum corticosterone level QTL 524.40.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)7131962314Rat
7411566Bw136Body weight QTL 13610.40.001body mass (VT:0001259)body weight gain (CMO:0000420)7131962314Rat

Markers in Region
ATP5B  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27516,480 - 516,617 (+)MAPPERmRatBN7.2
mRatBN7.2229,136,039 - 29,136,176 (+)MAPPERmRatBN7.2
Rnor_6.0225,599,724 - 25,599,860NCBIRnor6.0
Rnor_6.072,505,735 - 2,505,871NCBIRnor6.0
Rnor_5.072,485,122 - 2,485,258UniSTSRnor5.0
Rnor_5.0244,754,009 - 44,754,145UniSTSRnor5.0
RGSC_v3.4228,334,600 - 28,334,736UniSTSRGSC3.4
RGSC_v3.471,377,579 - 1,377,715UniSTSRGSC3.4
Celera7395,675 - 395,811UniSTS
Celera225,173,156 - 25,173,292UniSTS
Cytogenetic Map2q12UniSTS
Cytogenetic Map7q11UniSTS
RH127966  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.27520,984 - 521,753 (+)MAPPERmRatBN7.2
mRatBN7.2229,137,525 - 29,137,741 (+)MAPPERmRatBN7.2
Rnor_6.0225,601,210 - 25,601,425NCBIRnor6.0
Rnor_6.072,510,875 - 2,511,643NCBIRnor6.0
Rnor_5.072,489,465 - 2,490,233UniSTSRnor5.0
Rnor_5.0244,755,495 - 44,755,710UniSTSRnor5.0
RGSC_v3.4228,336,799 - 28,337,015UniSTSRGSC3.4
RGSC_v3.471,382,355 - 1,383,123UniSTSRGSC3.4
Celera7400,252 - 401,020UniSTS
Celera225,174,642 - 25,174,857UniSTS
Cytogenetic Map2q12UniSTS
Cytogenetic Map7q11UniSTS
AW549786  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr871,105,619 - 1,106,258 (+)Marker Load Pipeline
mRatBN7.27521,016 - 521,655 (+)MAPPERmRatBN7.2
Rnor_6.072,510,907 - 2,511,545NCBIRnor6.0
Rnor_5.072,489,497 - 2,490,135UniSTSRnor5.0
RGSC_v3.471,382,387 - 1,383,025UniSTSRGSC3.4
Celera7400,284 - 400,922UniSTS
Cytogenetic Map7q11UniSTS
MARC_26134-26135:1030377217:1  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr871,101,951 - 1,102,527 (+)Marker Load Pipeline
mRatBN7.27517,347 - 517,923 (+)MAPPERmRatBN7.2
Rnor_6.072,506,602 - 2,507,177NCBIRnor6.0
Rnor_5.072,485,989 - 2,486,564UniSTSRnor5.0
RGSC_v3.471,378,446 - 1,379,021UniSTSRGSC3.4
Celera7396,542 - 397,117UniSTS
Cytogenetic Map7q11UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000003965   ⟹   ENSRNOP00000003965
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl71,100,059 - 1,106,462 (+)Ensembl
mRatBN7.2 Ensembl7515,460 - 567,273 (+)Ensembl
Rnor_6.0 Ensembl72,504,695 - 2,511,749 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000131550   ⟹   ENSRNOP00000099290
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl71,099,860 - 1,106,462 (+)Ensembl
RefSeq Acc Id: NM_134364   ⟹   NP_599191
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr871,100,058 - 1,106,461 (+)NCBI
mRatBN7.27515,454 - 521,858 (+)NCBI
Rnor_6.072,504,708 - 2,511,748 (+)NCBI
Rnor_5.072,484,095 - 2,490,338 (+)NCBI
RGSC_v3.471,376,552 - 1,383,228 (+)RGD
Celera7394,648 - 401,125 (+)RGD
Sequence:
RefSeq Acc Id: NP_599191   ⟸   NM_134364
- Peptide Label: precursor
- UniProtKB: Q499W0 (UniProtKB/Swiss-Prot),   P10719 (UniProtKB/Swiss-Prot),   A6KSA3 (UniProtKB/TrEMBL),   G3V6D3 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000003965   ⟸   ENSRNOT00000003965
Ensembl Acc Id: ENSRNOP00000099290   ⟸   ENSRNOT00000131550
Protein Domains
AAA+ ATPase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P10719-F1-model_v2 AlphaFold P10719 1-529 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13694922
Promoter ID:EPDNEW_R5447
Type:multiple initiation site
Name:Atp5f1b_1
Description:ATP synthase F1 subunit beta
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.072,504,709 - 2,504,769EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:621368 AgrOrtholog
BioCyc Gene G2FUF-35397 BioCyc
BioCyc Pathway PWY-7980 [ATP biosynthesis] BioCyc
BioCyc Pathway Image PWY-7980 BioCyc
Ensembl Genes ENSRNOG00000002840 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000131550 ENTREZGENE
Gene3D-CATH 2.40.10.170 UniProtKB/Swiss-Prot
  3.40.50.300 UniProtKB/Swiss-Prot
  Bovine Mitochondrial F1-atpase, Atp Synthase Beta Chain, Chain D, domain 3 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7937989 IMAGE-MGC_LOAD
InterPro AAA+_ATPase UniProtKB/Swiss-Prot
  ATP-synt_VA_C UniProtKB/Swiss-Prot
  ATP_synth_F1_bsu UniProtKB/Swiss-Prot
  ATPase_a/bsu_AS UniProtKB/Swiss-Prot
  ATPase_alpha/beta_chains UniProtKB/Swiss-Prot
  ATPase_F1/V1/A1_a/bsu_N UniProtKB/Swiss-Prot
  ATPase_F1/V1/A1_a/bsu_N_sf UniProtKB/Swiss-Prot
  ATPase_F1/V1/A1_a/bsu_nucl-bd UniProtKB/Swiss-Prot
  ATPase_F1/V1_b/a_C UniProtKB/Swiss-Prot
  P-loop_NTPase UniProtKB/Swiss-Prot
KEGG Report rno:171374 UniProtKB/Swiss-Prot
MGC_CLONE MGC:124522 IMAGE-MGC_LOAD
NCBI Gene 171374 ENTREZGENE
PANTHER ATP SYNTHASE UniProtKB/Swiss-Prot
  ATP SYNTHASE SUBUNIT BETA, MITOCHONDRIAL UniProtKB/Swiss-Prot
Pfam ATP-synt_ab UniProtKB/Swiss-Prot
  ATP-synt_ab_N UniProtKB/Swiss-Prot
  ATP-synt_VA_C UniProtKB/Swiss-Prot
PhenoGen Atp5f1b PhenoGen
PIRSF ATPase_subunit_beta UniProtKB/Swiss-Prot
PROSITE ATPASE_ALPHA_BETA UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000002840 RatGTEx
SMART AAA UniProtKB/Swiss-Prot
Superfamily-SCOP C-terminal domain of alpha and beta subunits of F1 ATP synthase UniProtKB/Swiss-Prot
  SSF50615 UniProtKB/Swiss-Prot
  SSF52540 UniProtKB/Swiss-Prot
UniProt A6KSA3 ENTREZGENE, UniProtKB/TrEMBL
  ATPB_RAT UniProtKB/Swiss-Prot
  G3V6D3 ENTREZGENE, UniProtKB/TrEMBL
  P10719 ENTREZGENE
  Q499W0 ENTREZGENE
UniProt Secondary Q499W0 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-11-30 Atp5f1b  ATP synthase F1 subunit beta  Atp5b  ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-09-25 Atp5b  ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide  Atp5b  ATP synthase, H+ transporting mitochondrial F1 complex, beta subunit  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-02-22 Atp5b  ATP synthase, H+ transporting mitochondrial F1 complex, beta subunit  Atp5b  ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-20 Atp5b  ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide      Symbol and Name status set to approved 1299863 APPROVED
2002-08-07 Atp5b  ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide      Symbol and Name status set to provisional 70820 PROVISIONAL