Mmp2 (matrix metallopeptidase 2) - Rat Genome Database

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Gene: Mmp2 (matrix metallopeptidase 2) Rattus norvegicus
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Symbol: Mmp2
Name: matrix metallopeptidase 2
RGD ID: 621316
Description: Enables fibronectin binding activity and peptidase activity. Involved in several processes, including cellular response to estradiol stimulus; circulatory system development; and reproductive structure development. Located in extracellular space. Used to study artery disease (multiple); conjunctivitis; proteinuria; and transient cerebral ischemia. Biomarker of several diseases, including acute necrotizing pancreatitis; artery disease (multiple); bile duct disease (multiple); brain ischemia (multiple); and liver cirrhosis (multiple). Human ortholog(s) of this gene implicated in artery disease (multiple); eye disease (multiple); pseudoxanthoma elasticum; and temporal arteritis. Orthologous to human MMP2 (matrix metallopeptidase 2); PARTICIPATES IN syndecan signaling pathway; gonadotropin-releasing hormone signaling pathway; urinary bladder cancer pathway; INTERACTS WITH (-)-epigallocatechin 3-gallate; (R)-lipoic acid; (R)-noradrenaline.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: 72 kDa gelatinase; 72 KDa type IV collagenase; gelatinase A; matrix metalloproteinase 2; matrix metalloproteinase 2 (72 KDa type IV collagenase); matrix metalloproteinase-2; MMP-2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: Mmp2em2Mcwi  
Genetic Models: SS-Mmp2em1Mcwi-/- SS-Mmp2em2Mcwi
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21914,154,657 - 14,182,870 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1914,154,657 - 14,182,870 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1915,850,377 - 15,877,927 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01921,045,167 - 21,072,719 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01923,990,811 - 24,019,370 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01915,542,771 - 15,570,589 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1915,542,765 - 15,570,611 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01926,629,728 - 26,658,966 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41915,246,036 - 15,275,061 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1914,077,766 - 14,105,839 (-)NCBICelera
Cytogenetic Map19p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
abdominal aortic aneurysm  (IDA,IEP,ISO)
Acute Lung Injury  (IEP)
acute necrotizing pancreatitis  (IEP)
Acute Otitis Media  (ISO)
adrenoleukodystrophy  (ISO)
alcohol use disorder  (IEP)
alcoholic liver cirrhosis  (ISO)
Alveolar Bone Loss  (IEP)
Alzheimer's disease  (ISO)
amyotrophic lateral sclerosis  (ISO)
Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis  (ISO)
aortic disease  (ISO)
aortic dissection  (ISO)
Aortic Rupture  (ISO)
aortic valve disease 2  (ISO)
arteriosclerosis  (ISO)
Arteriovenous Fistula  (IEP,ISO)
atherosclerosis  (IEP,ISO)
atrial fibrillation  (ISO)
Behcet's disease  (ISO)
bone disease  (ISO)
Bone Neoplasms  (ISO)
brain ischemia  (IEP)
Breast Neoplasms  (ISO)
calcinosis  (ISO)
Cardiomegaly  (IEP)
cardiomyopathy  (ISO)
carotid artery disease  (ISO)
Carotid Artery Injuries  (IEP)
carotid stenosis  (ISO)
Cerebral Hemorrhage  (ISO)
cerebral infarction  (ISO)
cervix uteri carcinoma in situ  (ISO)
Chemical and Drug Induced Liver Injury  (ISO)
Chlamydophila Infections  (ISO)
cholangiocarcinoma  (IEP,ISO)
cholestasis  (IEP)
cholesteatoma  (ISO)
cholesteatoma of middle ear  (ISO)
Choroidal Neovascularization  (IDA,ISO)
Chronic Periodontitis  (IDA,ISO)
colon adenocarcinoma  (ISO)
colorectal cancer  (ISO)
Colorectal Neoplasms  (IEP,ISO)
congestive heart failure  (IEP,ISO)
conjunctivitis  (IDA)
COVID-19  (ISO)
Craniofacial Abnormalities  (ISO)
cutaneous leishmaniasis  (ISO)
Diabetic Nephropathies  (IEP,IMP)
diabetic neuropathy  (ISO)
diabetic retinopathy  (ISO)
dilated cardiomyopathy  (ISO)
Disease Progression  (ISO)
ductal carcinoma in situ  (ISO)
Embolism  (ISO)
end stage renal disease  (ISO)
Endometrial Neoplasms  (ISO)
endometriosis  (IEP)
esophagus squamous cell carcinoma  (ISO)
Experimental Autoimmune Encephalomyelitis  (IDA)
Experimental Colitis  (IEP)
Experimental Diabetes Mellitus  (ISO)
Experimental Liver Cirrhosis  (ISO)
Experimental Liver Neoplasms  (IEP,ISO)
Experimental Mammary Neoplasms  (IEP,ISO)
extrahepatic cholestasis  (ISO)
Fetal Growth Retardation  (ISO)
Fibrosis  (IEP)
focal segmental glomerulosclerosis  (IEP)
Gallbladder Neoplasms  (ISO)
gastric ulcer  (IEP)
genetic disease  (ISO)
glioblastoma  (ISO)
Gouty Arthritis  (ISO)
Graft Occlusion, Vascular  (ISO)
head and neck squamous cell carcinoma  (ISO)
heart valve disease  (ISO)
hemangioma  (ISO)
hepatocellular carcinoma  (ISO)
Herpes Simplex Encephalitis  (ISO)
high grade glioma  (IEP)
Hydatidiform Mole  (ISO)
Hyperoxia  (IEP)
Hyperplasia  (IEP)
hypertension  (IEP,ISO)
Hypertensive Nephropathy  (IMP)
hypertrophic cardiomyopathy  (ISO)
immunoglobulin light chain amyloidosis  (ISO)
Inflammation  (ISO)
intracranial aneurysm  (IEP,ISO)
ischemia  (ISO)
Joubert syndrome 1  (ISO)
keratoconus  (ISO)
laryngeal squamous cell carcinoma  (ISO)
Left Ventricular Hypertrophy  (IDA)
leiomyoma  (ISO)
liver cirrhosis  (IEP,ISO)
lung non-small cell carcinoma  (ISO)
lupus nephritis  (ISO)
Lymphatic Metastasis  (ISO)
macular degeneration  (ISO)
Malignant Pleural Effusions  (ISO)
Mandibular Diseases  (ISO)
Marfan syndrome  (ISO)
Maxillary Diseases  (ISO)
Metabolic Bone Diseases  (ISO)
Multiple Organ Failure  (ISO)
myocardial infarction  (IDA,IEP,ISO)
Myocardial Reperfusion Injury  (IEP,ISO)
myocarditis  (ISO)
myopia  (ISO)
Nasal Polyps  (ISO)
Nasopharyngeal Neoplasms  (ISO)
Neointima  (IEP,ISO)
Neoplasm Invasiveness  (ISO)
Neoplasm Metastasis  (IEP,ISO)
Nephrogenic Fibrosing Dermopathy  (ISO)
Nose Neoplasms  (ISO)
ocular hypertension  (IEP)
Oral Lichen Planus  (ISO)
oral submucous fibrosis  (ISO)
osteoarthritis  (ISO)
Osteolysis  (ISO)
Osteolysis Hereditary Multicentric  (ISO)
osteonecrosis  (ISO)
osteosarcoma  (ISO)
Ovarian Neoplasms  (ISO)
pancreatic cancer  (ISO)
pancreatic ductal carcinoma  (ISO)
papilloma  (ISO)
paracoccidioidomycosis  (ISO)
Perennial Allergic Rhinitis  (ISO)
periodontitis  (IEP)
Pneumococcal Meningitis  (IMP)
polycystic ovary syndrome  (IEP)
Polypoidal Choroidal Vasculopathy  (ISO)
pre-eclampsia  (ISO)
primary biliary cholangitis  (IEP)
prostate cancer  (ISO)
proteinuria  (IMP)
pseudoxanthoma elasticum  (ISO)
pterygium  (ISO)
pulmonary embolism  (IDA)
pulmonary emphysema  (IEP,ISO)
pulmonary fibrosis  (ISO)
Puromycin Aminonucleoside Nephrosis  (IEP)
pyoderma gangrenosum  (ISO)
renal cell carcinoma  (ISO)
renal hypertension  (IDA)
respiratory syncytial virus infectious disease  (ISO)
retinal vein occlusion  (ISO)
rheumatoid arthritis  (ISO)
Right Ventricular Hypertrophy  (IEP)
Sepsis  (IMP)
skin melanoma  (ISO)
Spinal Cord Injuries  (IEP)
squamous cell carcinoma  (ISO)
stomach carcinoma  (IEP)
Stroke  (IEP,ISO)
Sturge-Weber syndrome  (ISO)
Subarachnoid Hemorrhage  (IDA)
Sweet syndrome  (ISO)
temporal arteritis  (ISO)
Testicular Germ Cell Tumor  (ISO)
thoracic aortic aneurysm  (IEP,ISO)
transient cerebral ischemia  (IDA,IEP)
transitional cell carcinoma  (ISO)
traumatic brain injury  (IEP)
tropical spastic paraparesis  (ISO)
type 2 diabetes mellitus  (ISO)
Ulcer  (IEP,ISO)
urinary bladder cancer  (ISO)
Uterine Cervical Neoplasms  (ISO)
vascular dementia  (IEP)
Venous Thrombosis  (IDA,IEP)
Weight Gain  (ISO)
Winchester syndrome  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-Tetrandrine  (ISO)
(-)-epigallocatechin 3-gallate  (EXP,ISO)
(1->4)-beta-D-glucan  (ISO)
(20S)-ginsenoside Rg3  (ISO)
(R)-lipoic acid  (EXP)
(R)-noradrenaline  (EXP,ISO)
(S)-naringenin  (ISO)
(S)-nicotine  (EXP,ISO)
1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane  (ISO)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
1-chloro-2,4,6-trinitrobenzene  (ISO)
1-hydroxy-1-norresistomycin  (ISO)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (EXP,ISO)
17beta-estradiol 3-benzoate  (EXP)
17beta-hydroxy-17-methylestra-4,9,11-trien-3-one  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3-dihydroxybenzoic acid  (ISO)
2,4,6-tribromophenol  (ISO)
2,4,6-trinitrobenzenesulfonic acid  (ISO)
2-acetamidofluorene  (EXP)
2-amino-2-deoxy-D-glucopyranose  (EXP,ISO)
2-butoxyethanol  (ISO)
2-deoxy-D-glucose  (ISO)
2-Hydroxy-6-(8,11,14-pentadecatrienyl)benzoic acid  (ISO)
2-hydroxypropanoic acid  (ISO)
3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine  (EXP)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3,3',5-triiodo-L-thyronine  (EXP,ISO)
3,3'-diindolylmethane  (ISO)
3-hydroxypicolinic acid  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
3-methyladenine  (ISO)
3-methylcholanthrene  (EXP)
3-Nitrobenzanthrone  (ISO)
3-phenylprop-2-enal  (ISO)
4,4'-diaminodiphenylmethane  (EXP)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxy-17beta-estradiol  (ISO)
4-hydroxy-TEMPO  (EXP)
4-hydroxynon-2-enal  (EXP,ISO)
4-hydroxyphenyl retinamide  (ISO)
4-Nerolidylcatechol  (ISO)
5,6alpha-epoxy-5alpha-cholestan-3beta-ol  (EXP)
5-aminolevulinic acid  (EXP)
5-aza-2'-deoxycytidine  (ISO)
5-chloro-7-iodoquinolin-8-ol  (ISO)
5-fluorouracil  (ISO)
5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole  (EXP)
6-propyl-2-thiouracil  (EXP)
7,12-dimethyltetraphene  (ISO)
7-ketocholesterol  (EXP,ISO)
9,10-phenanthroquinone  (ISO)
[6]-Shogaol  (ISO)
acetaldehyde  (EXP,ISO)
acetamide  (EXP)
acetylsalicylic acid  (EXP,ISO)
acrolein  (ISO)
acrylamide  (EXP)
aflatoxin B1  (EXP,ISO)
Aflatoxin B2 alpha  (ISO)
ageladine A  (ISO)
AICA ribonucleotide  (ISO)
alachlor  (EXP)
aldehydo-D-glucosamine  (EXP,ISO)
aldehydo-D-glucose  (EXP,ISO)
alendronic acid  (EXP,ISO)
all-trans-retinoic acid  (EXP,ISO)
allyl isothiocyanate  (ISO)
alpha-D-galactose  (EXP)
alpha-mangostin  (ISO)
alpha-naphthoflavone  (EXP,ISO)
alternariol  (ISO)
Altertoxin II  (ISO)
aluminium atom  (EXP)
aluminium oxide  (ISO)
aluminium(0)  (EXP)
AM-251  (ISO)
ambroxol  (EXP)
amitrole  (ISO)
ammonium chloride  (EXP)
anagliptin  (ISO)
andrographolide  (ISO)
anethole  (ISO)
anthra[1,9-cd]pyrazol-6(2H)-one  (EXP,ISO)
antimycin A  (ISO)
apigenin  (ISO)
arachidonic acid  (ISO)
arecoline  (EXP,ISO)
arsane  (EXP,ISO)
arsenic atom  (EXP,ISO)
arsenite(3-)  (ISO)
arsenous acid  (EXP,ISO)
astemizole  (EXP)
atorvastatin calcium  (EXP,ISO)
ATP  (ISO)
atrazine  (ISO)
azoxystrobin  (ISO)
Bacoside a  (EXP)
baicalein  (ISO)
beclomethasone  (ISO)
benazepril  (EXP)
benomyl  (ISO)
benzalkonium chloride  (EXP)
benzene  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (ISO)
berberine  (EXP,ISO)
beta-aminopropionitrile  (EXP)
beta-D-glucosamine  (EXP,ISO)
beta-naphthoflavone  (EXP)
betulin  (EXP)
betulinic acid  (EXP,ISO)
bicalutamide  (ISO)
biochanin A  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bis(2-ethylhexyl) phthalate  (EXP,ISO)
bisdemethoxycurcumin  (ISO)
bisphenol A  (EXP,ISO)
Bisphenol A diglycidyl ether  (EXP)
Bisphenol B  (ISO)
bisphenol F  (ISO)
bleomycin A2  (EXP,ISO)
boric acid  (ISO)
brazilein  (ISO)
brucine  (ISO)
bucladesine  (ISO)
bufalin  (ISO)
butein  (ISO)
Butylbenzyl phthalate  (ISO)
C.I. Natural Red 20  (ISO)
C60 fullerene  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
calciol  (ISO)
calcitriol  (ISO)
calcium dichloride  (EXP,ISO)
cannabidiol  (ISO)
cantharidin  (ISO)
capecitabine  (ISO)
capsaicin  (EXP,ISO)
carbendazim  (ISO)
carbon nanotube  (ISO)
carfilzomib  (EXP)
carvedilol  (EXP,ISO)
carvone  (ISO)
casticin  (ISO)
celastrol  (EXP)
celecoxib  (EXP,ISO)
CGP 52608  (ISO)
CGS-21680  (ISO)
Chebulagic acid  (EXP)
chenodeoxycholic acid  (ISO)
CHIR 99021  (ISO)
chitosan  (EXP)
chlordecone  (ISO)
chloroquine  (ISO)
chlorpyrifos  (ISO)
choline  (ISO)
chromium atom  (ISO)
chromium(6+)  (ISO)
chrysin  (ISO)
ciprofloxacin  (EXP)
cisplatin  (ISO)
cobalt dichloride  (ISO)
coenzyme Q10  (EXP)
columbamine  (ISO)
conjugated linoleic acid  (ISO)
copper atom  (EXP,ISO)
copper(0)  (EXP,ISO)
copper(II) chloride  (EXP)
cordycepin  (ISO)
coumarin  (ISO)
crocidolite asbestos  (ISO)
cucurbitacin B  (ISO)
Cuprizon  (EXP)
curcumin  (EXP,ISO)
cycloheximide  (ISO)
cyclosporin A  (EXP)
D-glucose  (EXP,ISO)
DDE  (ISO)
DDT  (EXP)
deguelin  (ISO)
demethoxycurcumin  (ISO)
desferrioxamine B  (ISO)
Destruxin B  (ISO)
dexamethasone  (EXP,ISO)
dextran sulfate  (ISO)
diallyl disulfide  (ISO)
Diallyl sulfide  (EXP,ISO)
diallyl trisulfide  (ISO)
diarsenic trioxide  (EXP,ISO)
dibenziodolium  (EXP)
dibutyl phthalate  (EXP,ISO)
Dictamnine  (ISO)
dieckol  (ISO)
diethyl maleate  (EXP)
dihydroartemisinin  (ISO)
diisononyl phthalate  (ISO)
dimethyl sulfoxide  (EXP)
dimethylarsinous acid  (ISO)
diosgenin  (EXP)
dioxygen  (EXP,ISO)
diquat  (ISO)
disodium cromoglycate  (EXP)
disodium selenite  (EXP,ISO)
disulfiram  (ISO)
diuron  (EXP)
divanadium pentaoxide  (ISO)
dorsomorphin  (ISO)
doxorubicin  (EXP,ISO)
doxycycline  (EXP,ISO)
EC 3.1.1.4 (phospholipase A2) inhibitor  (ISO)
EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor  (ISO)
edaravone  (EXP)
elemental selenium  (ISO)
ellagic acid  (ISO)
embelin  (ISO)
emetine  (ISO)
endosulfan  (ISO)
entinostat  (ISO)
erlotinib hydrochloride  (ISO)
ethanol  (EXP,ISO)
eugenol  (EXP,ISO)
excitatory amino acid agonist  (ISO)
farrerol  (EXP)
fenbendazole  (ISO)
fenofibrate  (ISO)
ferric oxide  (ISO)
ferrichrome  (ISO)
Fexofenadine hydrochloride  (ISO)
fisetin  (ISO)
flavonol  (ISO)
fluvastatin  (ISO)
folic acid  (ISO)
fosinopril  (ISO)
fructose  (ISO)
fucoidan  (ISO)
fulvestrant  (ISO)
furan  (EXP)
galactose  (EXP)
gallic acid  (EXP,ISO)
Garcinol  (ISO)
gatifloxacin  (EXP)
Genipin  (ISO)
Geniposide pentaacetate  (EXP)
genistein  (EXP,ISO)
Geraniin  (ISO)
geraniol  (EXP)
gingerol  (ISO)
Ginkgoic acid  (ISO)
ginsenoside Rg1  (EXP)
glucose  (EXP,ISO)
glutathione  (ISO)
Gly-His-Lys  (EXP)
glycidol  (EXP)
glycyrrhizinic acid  (ISO)
graphene oxide  (ISO)
graphite  (EXP)
harmaline  (ISO)
heparin  (ISO)
hesperidin  (EXP)
Hexachloro-1,3-butadiene  (EXP)
hexachlorobenzene  (ISO)
hexadecanoic acid  (ISO)
hinokiflavone  (ISO)
hyaluronic acid  (ISO)
hydrogen peroxide  (EXP,ISO)
hydrogen sulfide  (EXP)
hydroquinone  (ISO)
hydroxamic acid  (ISO)
hydroxychloroquine  (ISO)
ibuprofen  (EXP)
ICI 118551  (ISO)
Indeno[1,2,3-cd]pyrene  (ISO)
indinavir  (EXP)
indometacin  (EXP,ISO)
inulin  (ISO)
irigenin  (ISO)
irinotecan  (ISO)
iron trichloride  (ISO)
isoliquiritigenin  (ISO)
isoprenaline  (EXP,ISO)
isotretinoin  (ISO)
JTE-013  (ISO)
juglone  (ISO)
kaempferol  (ISO)
L-ascorbic acid  (EXP,ISO)
L-ascorbic acid 2-phosphate  (ISO)
L-cysteine  (ISO)
L-methionine  (ISO)
lasofoxifene  (EXP)
lead diacetate  (EXP)
lead(0)  (EXP)
leflunomide  (EXP)
letrozole  (ISO)
leuprolide  (EXP)
lipoic acid  (EXP)
lipopolysaccharide  (EXP,ISO)
lisinopril dihydrate  (EXP)
lithocholic acid  (ISO)
loliolide  (ISO)
lomefloxacin  (EXP)
losartan  (EXP,ISO)
lovastatin  (ISO)
LY294002  (EXP,ISO)
lycopene  (ISO)
manganese atom  (ISO)
manganese(0)  (ISO)
mannuronic acid  (EXP)
marimastat  (ISO)
medroxyprogesterone acetate  (ISO)
melatonin  (EXP,ISO)
melittin  (ISO)
menadione  (ISO)
mercury atom  (ISO)
mercury(0)  (ISO)
metformin  (ISO)
methamphetamine  (ISO)
Methanandamide  (ISO)
methotrexate  (EXP)
methyl caffeate  (ISO)
methylcobalamin  (EXP)
methylisothiazolinone  (ISO)
methylmercury chloride  (ISO)
methylparaben  (ISO)
metoprolol  (EXP,ISO)
microcystin-LR  (EXP,ISO)
mifepristone  (EXP,ISO)
minocycline  (EXP,ISO)
miquelianin  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
monocrotaline  (EXP,ISO)
morin  (EXP)
morusin  (ISO)
moxifloxacin  (EXP)
N-acetyl-1,4-benzoquinone imine  (ISO)
N-acetyl-L-cysteine  (EXP,ISO)
N-methyl-N'-nitro-N-nitrosoguanidine  (EXP,ISO)
N-nitrosodiethylamine  (EXP,ISO)
N-nitrosodimethylamine  (EXP)
naproxen  (EXP)
naringin  (ISO)
Neferine  (ISO)
nerolidol  (EXP)
nickel atom  (ISO)
nickel dichloride  (ISO)
nickel sulfate  (ISO)
niclosamide  (ISO)
nicotine  (EXP,ISO)
nitric oxide  (EXP,ISO)
nitroglycerin  (ISO)
Nonylphenol  (ISO)
NORCANTHARIDIN  (ISO)
norfloxacin  (EXP)
obeticholic acid  (EXP)
ochratoxin A  (ISO)
okadaic acid  (ISO)
oleanolic acid  (ISO)
oleic acid  (ISO)
omeprazole  (EXP)
oridonin  (ISO)
oroxylin A  (ISO)
osthole  (ISO)
ouabain  (ISO)
oxaliplatin  (EXP)
oxytocin  (EXP)
ozone  (EXP,ISO)
p-cresol  (ISO)
paclitaxel  (EXP,ISO)
paracetamol  (EXP,ISO)
paraquat  (EXP,ISO)
PCB138  (EXP)
pentachlorophenol  (ISO)
pentanal  (ISO)
pentane-2,3-dione  (EXP)
perfluorohexanesulfonic acid  (ISO)
perfluorooctane-1-sulfonic acid  (EXP,ISO)
perfluorooctanoic acid  (EXP,ISO)
perindopril  (EXP,ISO)
phenanthrolines  (EXP)
phenethyl caffeate  (EXP)
phenylarsine oxide  (ISO)
phenylephrine  (EXP,ISO)
phenylmercury acetate  (ISO)
phenytoin  (ISO)
PhIP  (ISO)
phorbol 13-acetate 12-myristate  (ISO)
phosphatidic acid  (ISO)
phosphatidylcholine  (EXP)
picoxystrobin  (ISO)
picropodophyllotoxin  (ISO)
piperine  (ISO)
pipoxolan  (ISO)
pirfenidone  (EXP)
piroxicam  (ISO)
platycodin D  (EXP)
plumbagin  (ISO)
potassium bromate  (EXP)
potassium chromate  (ISO)
potassium dichromate  (ISO)
pravastatin  (EXP)
prazosin  (EXP)
prednisolone  (EXP)
prinomastat  (ISO)
probucol  (ISO)
progesterone  (ISO)
propanal  (ISO)
propofol  (ISO)
propranolol  (ISO)
prostaglandin E2  (ISO)
prostaglandin F2alpha  (ISO)
protein kinase inhibitor  (ISO)
protoporphyrin  (ISO)
pterostilbene  (ISO)
puerarin  (EXP)
pyrrolidine dithiocarbamate  (EXP,ISO)
quercetin  (EXP,ISO)
quercetin 3-O-beta-D-glucofuranoside  (ISO)
quercetin 3-O-beta-D-glucopyranoside  (ISO)
rac-lactic acid  (ISO)
radon atom  (ISO)
radon(0)  (ISO)
raloxifene  (EXP,ISO)
ramipril  (EXP)
razoxane  (EXP)
reactive oxygen species  (ISO)
Rebamipide  (EXP)
rebaudioside A  (EXP)
resveratrol  (EXP,ISO)
retinyl acetate  (ISO)
rhodotorulic acid  (ISO)
rosmarinic acid  (EXP)
rotenone  (EXP,ISO)
rottlerin  (ISO)
rutin  (ISO)
S-adenosyl-L-homocysteine  (EXP,ISO)
S-adenosyl-L-methioninate  (ISO)
S-adenosyl-L-methionine  (ISO)
S-allylcysteine  (EXP)
Salinomycin  (ISO)
Salvianolic acid A  (ISO)
sanguinarine  (ISO)
saxagliptin  (EXP)
SB 203580  (EXP,ISO)
SB 431542  (ISO)
scoparone  (ISO)
selenium atom  (ISO)
selumetinib  (ISO)
serpentine asbestos  (ISO)
Shikonin  (ISO)
silibinin  (EXP,ISO)
silicon dioxide  (EXP,ISO)
simvastatin  (EXP,ISO)
sirolimus  (EXP,ISO)
sodium arsenite  (EXP,ISO)
sodium chloride  (ISO)
sodium silicate  (EXP)
solasodine  (ISO)
Sophoricoside  (ISO)
sorafenib  (ISO)
sparfloxacin  (EXP)
sphingosine 1-phosphate  (ISO)
squalene  (EXP)
streptozocin  (EXP,ISO)
sulfasalazine  (EXP)
sulforaphane  (ISO)
sumatriptan  (EXP)
sunitinib  (ISO)
T-2 toxin  (ISO)
tamoxifen  (ISO)
tanespimycin  (ISO)
Tanshinone I  (ISO)
taurocholic acid  (ISO)
tebuconazole  (ISO)
telmisartan  (EXP)
temozolomide  (ISO)
terazosin  (EXP)
terbinafine  (ISO)
testosterone  (EXP)
tetracaine  (ISO)
tetrachloromethane  (EXP,ISO)
tetracycline  (ISO)
tetrahydrocurcumin  (ISO)
tetraphene  (ISO)
thalidomide  (ISO)
thioacetamide  (EXP,ISO)
thymoquinone  (ISO)
thyroxine  (EXP)
titanium atom  (ISO)
titanium dioxide  (ISO)
tolfenamic acid  (ISO)
tomatidine  (ISO)
Tomentosin  (ISO)
topotecan  (EXP)
trans-anethole  (ISO)
trans-cinnamic acid  (ISO)
trans-rhaponticin  (EXP)
tributylstannane  (EXP)
trichloroethene  (EXP)
trichostatin A  (ISO)
triciribine  (ISO)
triclosan  (ISO)
triphenyl phosphate  (EXP)
Triptolide  (ISO)
triptonide  (ISO)
troglitazone  (ISO)
tropisetron  (EXP)
tyrphostin AG 1478  (ISO)
ubiquinone-0  (ISO)
urethane  (ISO)
ursodeoxycholic acid  (EXP)
ursolic acid  (EXP,ISO)
Ursonic acid  (ISO)
valproic acid  (ISO)
valsartan  (ISO)
varespladib methyl  (ISO)
vinclozolin  (EXP)
vitamin E  (EXP,ISO)
vorinostat  (EXP,ISO)
WIN 55212-2  (ISO)
withaferin A  (ISO)
wogonin  (ISO)
wortmannin  (ISO)
Y-27632  (ISO)
zafirlukast  (ISO)
zearalenone  (ISO)
zerumbone  (ISO)
zidovudine  (EXP)
zinc atom  (ISO)
zinc dichloride  (ISO)
zinc oxide  (ISO)
zinc protoporphyrin  (EXP,ISO)
zinc(0)  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
angiogenesis  (IEP)
blood vessel maturation  (IEA,ISO)
bone trabecula formation  (IEA,ISO)
cell migration  (IMP)
cellular response to amino acid stimulus  (IEA,ISO)
cellular response to cytokine stimulus  (IEP)
cellular response to estradiol stimulus  (IMP)
cellular response to fluid shear stress  (IEP)
cellular response to interleukin-1  (IEP)
cellular response to reactive oxygen species  (IEA,ISO)
cellular response to UV-A  (IEA,ISO,ISS)
collagen catabolic process  (IBA,IDA,IEA,ISO)
embryo implantation  (IEA,ISO)
endodermal cell differentiation  (IEA,ISO)
extracellular matrix organization  (IBA,IEA)
face morphogenesis  (IEA,ISO)
female pregnancy  (IEP)
heart development  (IDA)
intramembranous ossification  (IEA,ISO)
luteinization  (IEP)
macrophage chemotaxis  (IDA)
negative regulation of cell adhesion  (IDA)
negative regulation of vasoconstriction  (IDA)
ovarian follicle development  (IDA)
ovulation from ovarian follicle  (IEP)
parturition  (IEP)
peripheral nervous system axon regeneration  (IDA)
positive regulation of apoptotic process  (IDA)
positive regulation of cell migration  (IMP)
positive regulation of innate immune response  (ISO)
positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway  (IMP)
positive regulation of smooth muscle cell proliferation  (ISO)
positive regulation of vascular associated smooth muscle cell proliferation  (IEA,ISO)
prostate gland epithelium morphogenesis  (IMP)
protein catabolic process  (IDA)
proteolysis  (IDA,IEA,ISO)
response to activity  (IEP)
response to amyloid-beta  (IEA,ISO)
response to cytokine  (IEP)
response to electrical stimulus  (IEP)
response to estrogen  (IDA)
response to hydrogen peroxide  (IDA)
response to hyperoxia  (IEP)
response to hypoxia  (IBA,IDA,IEA,ISO)
response to mechanical stimulus  (IDA)
response to nicotine  (IEP)
response to oxidative stress  (IDA)
response to retinoic acid  (IEP)
response to xenobiotic stimulus  (IDA,IEP)
skeletal system morphogenesis  (ISO)
tissue remodeling  (IBA,IDA,IEA)

Cellular Component