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Gene: Atp2c1 (ATPase secretory pathway Ca2+ transporting 1) Rattus norvegicus

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Symbol:

Atp2c1

Name:

ATPase secretory pathway Ca2+ transporting 1

RGD ID:

621311

Description:

Enables P-type calcium transporter activity. Involved in calcium ion transport and intracellular calcium ion homeostasis. Located in secretory granule. Human ortholog(s) of this gene implicated in Hailey-Hailey disease. Orthologous to human ATP2C1 (ATPase secretory pathway Ca2+ transporting 1); PARTICIPATES IN calcium transport pathway; calcium/calcium-mediated signaling pathway; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

ATP-dependent Ca(2+) pump PMR1; ATPase 2C1; ATPase, Ca++ transporting, type 2C, member 1; ATPase, Ca++-sequestering; Ca(2+)/Mn(2+)-ATPase 2C1; calcium-transporting ATPase 2C1; calcium-transporting ATPase type 2C member 1; LOC103690457; MGC93231; secretory pathway Ca(2+)-ATPase 1; secretory pathway Ca(2+)-transporting ATPase type 1; Spca1; uncharacterized LOC103690457

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	ATP2C1 (ATPase secretory pathway Ca2+ transporting 1)	HGNC	Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther
Mus musculus (house mouse):	Atp2c1 (ATPase, Ca++-sequestering)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Atp2c1 (ATPase secretory pathway Ca2+ transporting 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	ATP2C1 (ATPase secretory pathway Ca2+ transporting 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	ATP2C1 (ATPase secretory pathway Ca2+ transporting 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Atp2c1 (ATPase secretory pathway Ca2+ transporting 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	ATP2C1 (ATPase secretory pathway Ca2+ transporting 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	ATP2C1 (ATPase secretory pathway Ca2+ transporting 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Atp2c1 (ATPase secretory pathway Ca2+ transporting 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	CD6 (CD6 molecule)	HGNC	OMA
Alliance orthologs ³
Homo sapiens (human):	ATP2C1 (ATPase secretory pathway Ca2+ transporting 1)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Atp2c1 (ATPase, Ca++-sequestering)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	atp2c1 (ATPase secretory pathway Ca2+ transporting 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Saccharomyces cerevisiae (baker's yeast):	PMR1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	SPoCk	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	pmr-1	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	atp2c1	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB)

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	8	114,913,551 - 115,034,706 (-)	NCBI		GRCr8
mRatBN7.2	8	106,034,777 - 106,155,854 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	8	106,034,636 - 106,156,006 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	8	111,672,126 - 111,755,122 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	8	109,871,371 - 109,954,375 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	8	107,714,075 - 107,797,076 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	8	113,953,959 - 114,039,965 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	8	113,955,647 - 114,013,623 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	8	113,341,077 - 113,426,614 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	8	110,516,092 - 110,603,620 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	8	110,562,294 - 110,623,075 (-)	NCBI
Celera	8	105,376,283 - 105,459,249 (-)	NCBI		Celera
Cytogenetic Map	8	q32	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

alkaptonuria (ISO)

genetic disease (ISO)

Hailey-Hailey disease (ISO)

immunodeficiency 21 (ISO)

Primary Lymphedema with Myelodysplasia (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(1->4)-beta-D-glucan (ISO)

1,2-dimethylhydrazine (ISO)

17beta-estradiol (EXP,ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,4-dinitrotoluene (EXP)

3,3',4,4',5-pentachlorobiphenyl (EXP)

3H-1,2-dithiole-3-thione (EXP)

4,4'-sulfonyldiphenol (ISO)

6-propyl-2-thiouracil (EXP)

acetamide (EXP)

acrolein (ISO)

acrylamide (ISO)

aflatoxin B1 (EXP)

alpha-pinene (ISO)

amitrole (EXP)

ammonium chloride (EXP)

arsane (ISO)

arsenic atom (ISO)

arsenite(3-) (ISO)

atrazine (ISO)

benzo[a]pyrene (ISO)

beta-lapachone (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

Brodifacoum (EXP)

cadmium atom (ISO)

cadmium dichloride (EXP)

carbamazepine (ISO)

carbon nanotube (ISO)

chlorpyrifos (ISO)

cisplatin (ISO)

clofibric acid (EXP)

cobalt dichloride (ISO)

copper(II) sulfate (ISO)

coumestrol (ISO)

elemental selenium (ISO)

endosulfan (EXP)

Enterolactone (ISO)

epoxiconazole (ISO)

ethanol (ISO)

fenvalerate (EXP)

flutamide (EXP)

fulvestrant (ISO)

genistein (EXP)

ivermectin (ISO)

lead(0) (ISO)

lidocaine (EXP)

lycopene (ISO)

manganese atom (ISO)

manganese(0) (ISO)

manganese(II) chloride (ISO)

methimazole (EXP)

mirex (EXP)

N-nitrosodiethylamine (EXP)

N-nitrosomorpholine (EXP)

nitrates (ISO)

ochratoxin A (ISO)

ozone (ISO)

perfluorooctane-1-sulfonic acid (ISO)

picoxystrobin (ISO)

potassium dichromate (ISO)

selenium atom (ISO)

sodium arsenate (ISO)

sodium arsenite (ISO)

Soman (EXP)

sunitinib (ISO)

tetrachloromethane (EXP)

titanium dioxide (ISO)

trichloroethene (ISO)

triphenyl phosphate (ISO)

triptonide (ISO)

valproic acid (ISO)

zinc atom (EXP)

zinc sulfate (EXP)

zinc(0) (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

actin cytoskeleton organization (IEA,ISO,ISS)

calcium ion import (IC)

calcium ion transmembrane transport (IBA,IEA)

calcium ion transport (IDA,IEA,IMP,ISO,ISS)

calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (IEA,ISO,ISS)

epidermis development (IEA,ISO,ISS)

Golgi calcium ion homeostasis (IEA,ISO,ISS)

Golgi calcium ion transport (IC,IEA,ISO,ISS)

intracellular calcium ion homeostasis (IBA,IEA,IMP,ISO,ISS)

intracellular manganese ion homeostasis (ISO,ISS)

manganese ion transmembrane transport (IEA)

manganese ion transport (IBA,ISO,ISS)

monoatomic ion transport (IEA)

positive regulation of canonical NF-kappaB signal transduction (ISS)

positive regulation of Golgi to plasma membrane protein transport (IEA,ISO,ISS)

trans-Golgi network membrane organization (IEA,ISO,ISS)

Cellular Component

cis-Golgi network membrane (IEA,ISO,ISS)

endomembrane system (IEA)

endoplasmic reticulum (IBA)

Golgi apparatus (IEA,ISO,ISS)

Golgi cisterna membrane (IEA,ISO,ISS)

Golgi membrane (IBA,IEA,ISO,ISS)

membrane (IEA)

plasma membrane (IBA)

secretory granule (IDA)

trans-Golgi network (IEA,ISO,ISS)

Molecular Function

ATP binding (IEA,ISO,ISS)

ATP hydrolysis activity (IEA)

calcium ion binding (ISO,ISS)

manganese ion binding (ISO,ISS)

metal ion binding (IEA)

nucleotide binding (IEA)

P-type calcium transporter activity (IBA,IDA,IEA,ISO,ISS)

P-type manganese transporter activity (IEA,ISO,ISS)

Molecular Pathway Annotations Click to see Annotation Detail View

calcium transport pathway (ISO)

calcium/calcium-mediated signaling pathway (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Calcium pumps in health and disease.	Brini M and Carafoli E, Physiol Rev. 2009 Oct;89(4):1341-78. doi: 10.1152/physrev.00032.2008.
2.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
4.	Molecular cloning and tissue distribution of alternatively spliced mRNAs encoding possible mammalian homologues of the yeast secretory pathway calcium pump.	Gunteski-Hamblin AM, etal., Biochemistry 1992 Aug 25;31(33):7600-8.
5.	Changes in expression and activity of the secretory pathway Ca2+ ATPase 1 (SPCA1) in A7r5 vascular smooth muscle cells cultured at different glucose concentrations.	Lai P and Michelangeli F, Biosci Rep. 2009 Sep 2;29(6):397-404. doi: 10.1042/BSR20090058.
6.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
7.	Role for plasma membrane-related Ca2+-ATPase-1 (ATP2C1) in pancreatic beta-cell Ca2+ homeostasis revealed by RNA silencing.	Mitchell KJ, etal., Diabetes. 2004 Feb;53(2):393-400.
8.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
9.	OMIM Disease Annotation Pipeline	OMIM Disease Annotation Pipeline
10.	RefSeq and LocusLink: NCBI gene-centered resources	Pruitt KD and Maglott DR, Nucleic Acids Res. 2001 Jan 1;29(1):137-40.
11.	Characterization of Cos-7 cells overexpressing the rat secretory pathway Ca2+-ATPase.	Reinhardt TA, etal., Am J Physiol Cell Physiol. 2004 Jan;286(1):C164-9. Epub 2003 Sep 10.
12.	GOA pipeline	RGD automated data pipeline
13.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
14.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
15.	The expression, activity and localisation of the secretory pathway Ca2+ -ATPase (SPCA1) in different mammalian tissues.	Wootton LL, etal., Biochim Biophys Acta. 2004 Aug 30;1664(2):189-97.

Additional References at PubMed

PMID:10615129	PMID:11741891	PMID:12477932	PMID:12707275	PMID:12761501	PMID:12804581	PMID:12810057	PMID:14632182	PMID:14632183	PMID:16192278	PMID:16758324	PMID:19946888
PMID:20981470	PMID:22871113	PMID:23840669	PMID:27133772	PMID:37539566

Genomics

Comparative Map Data

Atp2c1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	8	114,913,551 - 115,034,706 (-)	NCBI		GRCr8
mRatBN7.2	8	106,034,777 - 106,155,854 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	8	106,034,636 - 106,156,006 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	8	111,672,126 - 111,755,122 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	8	109,871,371 - 109,954,375 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	8	107,714,075 - 107,797,076 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	8	113,953,959 - 114,039,965 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	8	113,955,647 - 114,013,623 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	8	113,341,077 - 113,426,614 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	8	110,516,092 - 110,603,620 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	8	110,562,294 - 110,623,075 (-)	NCBI
Celera	8	105,376,283 - 105,459,249 (-)	NCBI		Celera
Cytogenetic Map	8	q32	NCBI

ATP2C1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	3	130,850,595 - 131,016,712 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	3	130,850,595 - 131,016,712 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	3	130,569,439 - 130,735,556 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	3	132,096,124 - 132,218,246 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	3	132,096,131 - 132,204,690	NCBI
Celera	3	129,038,713 - 129,160,803 (+)	NCBI		Celera
Cytogenetic Map	3	q22.1	NCBI
HuRef	3	127,954,018 - 128,119,693 (+)	NCBI		HuRef
CHM1_1	3	130,532,422 - 130,699,080 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	3	133,594,441 - 133,760,462 (+)	NCBI		T2T-CHM13v2.0

Atp2c1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	9	105,288,561 - 105,398,456 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	9	105,280,738 - 105,404,518 (-)	Ensembl		GRCm39 Ensembl
GRCm38	9	105,411,362 - 105,521,257 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	9	105,403,539 - 105,527,319 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	9	105,313,692 - 105,397,447 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	9	105,269,462 - 105,353,199 (-)	NCBI		MGSCv36	mm8
Celera	9	105,007,157 - 105,064,980 (-)	NCBI		Celera
Cytogenetic Map	9	F1	NCBI
cM Map	9	56.61	NCBI

Atp2c1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955501	7,383,150 - 7,519,988 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955501	7,382,657 - 7,519,789 (-)	NCBI	ChiLan1.0	ChiLan1.0

ATP2C1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	2	128,809,482 - 128,973,301 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	3	128,814,209 - 128,978,056 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	3	127,937,272 - 128,101,060 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	3	135,301,721 - 135,423,700 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	3	135,260,796 - 135,423,700 (+)	Ensembl	panpan1.1		panPan2

ATP2C1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	23	28,097,831 - 28,233,675 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	23	28,066,639 - 28,235,215 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	23	28,071,244 - 28,206,384 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	23	28,573,616 - 28,742,803 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	23	28,573,627 - 28,743,659 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	23	28,270,690 - 28,439,119 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	23	28,360,695 - 28,495,909 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	23	28,610,117 - 28,745,760 (+)	NCBI		UU_Cfam_GSD_1.0

Atp2c1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405602	67,579,716 - 67,714,373 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936529	4,361,424 - 4,474,436 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936529	4,340,131 - 4,474,884 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ATP2C1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	13	1,438,615 - 1,612,676 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	13	1,461,562 - 1,580,035 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	13	1,118,899 - 1,270,494 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

ATP2C1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	15	59,189,075 - 59,348,684 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	15	59,188,225 - 59,311,709 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666041	32,207,172 - 32,372,825 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Atp2c1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624730	6,865,197 - 7,001,378 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Atp2c1
753 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	250
Count of miRNA genes:	176
Interacting mature miRNAs:	202
Transcripts:	ENSRNOT00000018175, ENSRNOT00000045087
Prediction methods:	Microtar, Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
2303171	Bp331	Blood pressure QTL 331	5.57	0.005	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	8	105462581	132782436	Rat
1549909	Stresp11	Stress response QTL 11	6.83	0.0019	stress-related behavior trait (VT:0010451)	number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)	8	82352698	127352698	Rat
631210	Bw3	Body weight QTL3	5.9		mesenteric fat pad mass (VT:0010427)	mesenteric fat pad weight to body weight ratio (CMO:0000654)	8	61019838	121662124	Rat
1554321	Bmd3	Bone mineral density QTL 3	7.9	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	8	49849908	118871671	Rat
9590292	Uminl3	Urine mineral level QTL 3	3.62	0.001	urine mineral amount (VT:0015086)	urine electrolyte level (CMO:0000593)	8	80768445	125768445	Rat
8694446	Bw170	Body weight QTL 170	12.07	0.001	retroperitoneal fat pad mass (VT:0010430)	retroperitoneal fat pad weight to body weight ratio (CMO:0000635)	8	80768445	125768445	Rat
631650	Stl6	Serum triglyceride level QTL 6	4	0.0019	blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	8	70041301	121080908	Rat
1581557	Eae16	Experimental allergic encephalomyelitis QTL 16	3.8		nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)	8	68690349	119799881	Rat
10450865	Bw175	Body weight QTL 175	4.1		total fat pad mass (VT:0015008)	adipose tissue molecular composition measurement (CMO:0000484)	8	84192326	129192326	Rat
738011	Anxrr9	Anxiety related response QTL 9	6.1		exploratory behavior trait (VT:0010471)	number of entries into a discrete space in an experimental apparatus (CMO:0000960)	8	102413464	132782436	Rat
724539	Cm19	Cardiac mass QTL 19	2.6		heart mass (VT:0007028)	calculated heart weight (CMO:0000073)	8	103375781	129871912	Rat
70197	BpQTLcluster8	Blood pressure QTL cluster 8	3.482		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	8	55428333	127966348	Rat
634332	Pia18	Pristane induced arthritis QTL 18	4		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	8	84192326	132782436	Rat
2300181	Bmd55	Bone mineral density QTL 55	5.7	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	8	85348065	130348065	Rat
1300171	Bp184	Blood pressure QTL 184	3.66		arterial blood pressure trait (VT:2000000)	blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)	8	79394435	132782436	Rat
631217	Activ1	Activity QTL 1	15.9		voluntary movement trait (VT:0003491)	number of photobeam interruptions in an experimental apparatus (CMO:0001517)	8	111249511	117802327	Rat
2313400	Anxrr25	Anxiety related response QTL 25			aggression-related behavior trait (VT:0015014)	tameness/aggressiveness composite score (CMO:0002136)	8	98145073	122898010	Rat
8694200	Abfw4	Abdominal fat weight QTL 4	9.07	0.001	visceral adipose mass (VT:0010063)	abdominal fat pad weight to body weight ratio (CMO:0000095)	8	80768445	125768445	Rat
8694392	Bw161	Body weight QTL 161	8.06	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	8	80768445	125768445	Rat
61437	Cia6	Collagen induced arthritis QTL 6			joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	8	91340911	131690273	Rat

Markers in Region

D8Got171

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	8	106,086,869 - 106,087,053 (+)	MAPPER	mRatBN7.2
Rnor_6.0	8	113,995,621 - 113,995,804	NCBI	Rnor6.0
Rnor_5.0	8	113,382,649 - 113,382,832	UniSTS	Rnor5.0
RGSC_v3.4	8	110,558,156 - 110,558,340	RGD	RGSC3.4
RGSC_v3.4	8	110,558,157 - 110,558,340	UniSTS	RGSC3.4
RGSC_v3.1	8	110,577,611 - 110,577,795	RGD
Celera	8	105,414,948 - 105,415,131	UniSTS
Cytogenetic Map	8	q32	UniSTS

RH130674

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	8	106,074,430 - 106,074,635 (+)	MAPPER	mRatBN7.2
Rnor_6.0	8	113,983,215 - 113,983,419	NCBI	Rnor6.0
Rnor_5.0	8	113,370,200 - 113,370,404	UniSTS	Rnor5.0
RGSC_v3.4	8	110,545,335 - 110,545,539	UniSTS	RGSC3.4
Celera	8	105,401,957 - 105,402,161	UniSTS
Cytogenetic Map	8	q32	UniSTS

RH131266

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	8	106,043,610 - 106,043,793 (+)	MAPPER	mRatBN7.2
Rnor_6.0	8	113,954,013 - 113,954,195	NCBI	Rnor6.0
Rnor_5.0	8	113,341,131 - 113,341,313	UniSTS	Rnor5.0
RGSC_v3.4	8	110,516,146 - 110,516,328	UniSTS	RGSC3.4
Celera	8	105,376,337 - 105,376,519	UniSTS
RH 3.4 Map	8	1150.5	UniSTS
Cytogenetic Map	8	q32	UniSTS

RH133189

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	8	106,049,199 - 106,049,386 (+)	MAPPER	mRatBN7.2
Rnor_6.0	8	113,959,607 - 113,959,793	NCBI	Rnor6.0
Rnor_5.0	8	113,346,592 - 113,346,778	UniSTS	Rnor5.0
RGSC_v3.4	8	110,521,963 - 110,522,149	UniSTS	RGSC3.4
Celera	8	105,381,926 - 105,382,112	UniSTS
Cytogenetic Map	8	q32	UniSTS

BE114010

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	8	106,069,078 - 106,069,246 (+)	MAPPER	mRatBN7.2
Rnor_6.0	8	113,977,863 - 113,978,030	NCBI	Rnor6.0
Rnor_5.0	8	113,364,848 - 113,365,015	UniSTS	Rnor5.0
RGSC_v3.4	8	110,539,983 - 110,540,150	UniSTS	RGSC3.4
Celera	8	105,396,605 - 105,396,772	UniSTS
RH 3.4 Map	8	1151.6	UniSTS
Cytogenetic Map	8	q32	UniSTS

BF390084

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	8	106,034,833 - 106,034,986 (+)	MAPPER	mRatBN7.2
Rnor_6.0	8	113,945,255 - 113,945,407	NCBI	Rnor6.0
Rnor_5.0	8	113,330,792 - 113,330,944	UniSTS	Rnor5.0
RGSC_v3.4	8	110,506,791 - 110,506,943	UniSTS	RGSC3.4
Celera	8	105,367,562 - 105,367,714	UniSTS
RH 3.4 Map	8	1152.7	UniSTS
Cytogenetic Map	8	q32	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
9	11	49	113	91	90	59	25	59	6	218	97	93	45	60	31

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_131907	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039080729	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063264804	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063264805	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063264806	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063264807	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063264808	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063264809	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_005487741	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_010053920	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_010053921	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_010053922	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_010053923	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_010053924	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC086994	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473954	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ214054	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ214433	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000008	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	M93017	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	M93018	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000018175 ⟹ ENSRNOP00000018175

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	8	106,045,245 - 106,105,000 (-)	Ensembl
Rnor_6.0 Ensembl	8	113,955,647 - 114,013,623 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000045087 ⟹ ENSRNOP00000045953

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	8	106,035,069 - 106,131,314 (-)	Ensembl
Rnor_6.0 Ensembl	8	113,957,279 - 114,010,277 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000095638 ⟹ ENSRNOP00000096296

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	8	106,043,558 - 106,131,314 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000097914 ⟹ ENSRNOP00000088420

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	8	106,034,636 - 106,131,314 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000099084 ⟹ ENSRNOP00000076661

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	8	106,043,558 - 106,131,407 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000102340 ⟹ ENSRNOP00000083761

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	8	106,043,558 - 106,156,006 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000103991 ⟹ ENSRNOP00000085864

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	8	106,035,062 - 106,156,006 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000112729 ⟹ ENSRNOP00000089204

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	8	106,043,558 - 106,130,413 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000119741 ⟹ ENSRNOP00000097217

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	8	106,045,245 - 106,131,314 (-)	Ensembl

RefSeq Acc Id:

NM_131907 ⟹ NP_571982

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	8	114,922,334 - 115,010,081 (-)	NCBI
mRatBN7.2	8	106,043,557 - 106,131,314 (-)	NCBI
Rnor_6.0	8	113,953,959 - 114,039,965 (-)	NCBI
Rnor_5.0	8	113,341,077 - 113,426,614 (-)	NCBI
RGSC_v3.4	8	110,516,092 - 110,603,620 (-)	RGD
Celera	8	105,376,283 - 105,459,249 (-)	RGD

Sequence:

show sequence

AGCTCGGTGGGCGGCGGGCGGTGTAGTGCAGGGAGCGCCGGGCGGCGGGCGGCAGGGAGGGGCG
GAGCGCAGGAGGTGGAGGCGGGAGCAGAGCTGCTCGGCCGTGCGCGGAGACGCGCGGAGCCGGC
GGGCCAAGCTTGACGGGCCCCTCGCCGCTCCTCCTCTCCCCTCCCTGCCACCATCCTGCTCGTT
CTCCTCCGGACGCGGCTGGGCTCCGTGTGGCGCCACCGTGCCGCCAGCAGTGCCCGTTCGCCCG
AGGCGCGTGGGGCGCCCCCGCAGCCCCGCGAATGCTGCTGCTAGGGGTGGTGGGAGCAGCCGTG
GGACGCGTGGCCGGGAGCGGGGGTGACAGCCTGGGATTCCAGGGTCTTCTCTTCCTTGTCCTCC
TCCTCTCCTCTCTATTCCCAGTGTGGCCGTGGCTGACACTAAAGACTTTGTAGCCATCAACCAG
AGTGCAGTTTCGATGGAAAATGAAGGTTGCACGATTTCAAAAGATCCCTAATGTTGAAAATGAG
ACAATGATCCCTGTACTGACATCCAAGAGAGCAAGTGAGTTAGCAGTCAGTGAGGTCGCAGGCC
TTCTCCAGGCTGATCTTCAGAATGGCTTAAACAAATCTGAAGTTAGTCATAGGCGAGCCTTCCA
TGGCTGGAATGAGTTTGATATCAGTGAAGATGAACCATTATGGAAGAAGTACATTTCTCAGTTT
AAAAATCCCCTCATCATGCTGCTTCTGGCTTCGGCAGTCATCAGCGTTTTAATGCGTCAGTTTG
ATGATGCCGTCAGTATCACTGTGGCAATACTGATTGTTGTCACCGTGGCCTTTGTTCAGGAATA
TCGTTCAGAAAAATCTTTAGAAGAATTAAGTAAACTTGTGCCACCAGAATGCCATTGTGTTCGT
GAAGGAAAATTGGAGCATACACTTGCCCGAGACTTGGTTCCAGGTGATACAGTTTGTCTGTCTG
TGGGGGACAGAGTTCCTGCTGACTTACGCTTATTCGAGGCCGTGGATCTTTCCATCGATGAGTC
TAGCTTGACAGGAGAGACAACTCCTTGTTCTAAGGTGACCGCTCCTCAACCAGCTGCTACCAAT
GGGGATCTTGCATCAAGAAGTAACATTGCCTTCATGGGGACTCTGGTCAGATGTGGCAAAGCAA
AGGGTATTGTCATTGGAACAGGAGAGAATTCTGAATTTGGAGAGGTCTTTAAGATGATGCAGGC
AGAAGAAGCACCAAAAACGCCTCTGCAGAAGAGCATGGACCTCTTGGGCAAGCAGCTGTCCTTT
TACTCCTTTGGTATAATAGGTATCATCATGTTGGTTGGCTGGTTACTAGGGAAAGACATTCTGG
AAATGTTCACTATTAGTGTAAGTTTGGCTGTAGCTGCAATTCCTGAAGGTCTGCCTATTGTGGT
CACAGTGACACTAGCCCTTGGTGTTATGAGAATGGTGAAGAAAAGGGCTATTGTAAAGAAATTG
CCTATTGTTGAAACGCTGGGCTGCTGTAATGTGATTTGTTCAGATAAAACTGGAACCCTGACGA
AGAATGAGATGACTGTTACTCACATCCTCACTTCAGACGGCCTGCATGCTGAGGTTACTGGAGT
TGGCTACAATCAGTTTGGTGAAGTGATTGTTGATGGTGATGTTGTTCATGGATTCTATAACCCA
GCTGTTAGCAGAATTGTTGAGGCGGGCTGTGTGTGCAACGATGCTGTCATTAGGAACAACACTC
TGATGGGAAAGCCAACTGAAGGAGCCTTAATCGCTCTCGCGATGAAGATGGGTCTTGATGGACT
GCAACAAGACTATATCAGAAAAGCTGAATACCCTTTTAGTTCTGAGCAGAAATGGATGGCTGTT
AAGTGTGTGCACCGAACACAGCAGGACAGACCAGAGATTTGTTTTATGAAGGGTGCTTATGAGC
AGGTGATTAAGTATTGTACTACGTACAACAGCAAAGGGCAGACTTTGGCACTTACCCAGCAGCA
GAGAGATTTGTACCAACAAGAGAAGGCCCAGATGGGCTCGGCAGGACTCCGAGTTCTTGCACTG
GCGTCTGGTCCGGACCTGGGGCAGCTGACCTTCCTTGGCCTGGTAGGAATCATTGACCCTCCGA
GAACTGGTGTGAAAGAAGCCGTCACAACACTCATTGCCTCAGGAGTCTCCATCAAAATGATCAC
AGGAGACTCTCAGGAGACTGCAATTGCAATCGCTAGTCGTCTGGGATTGTATTCTAAAACTTCA
CAGTCTGTGTCTGGAGAAGAAGTAGATACAATGGAAGTCCAGCACCTTTCACAGATAGTGCCAA
AGGTTGCAGTATTTTACAGAGCAAGCCCAAGACACAAGATGAAAATTATTAAGTCTCTACAAAA
GAACGGGTCAGTTGTAGCCATGACAGGAGATGGGGTAAATGATGCAGTGGCTCTGAAGGCTGCA
GATATTGGAGTTGCAATGGGCCAGACTGGCACAGATGTTTGCAAAGAGGCTGCGGACATGATCT
TGGTGGATGATGATTTCCAAACTATAATGTCTGCAATAGAAGAGGGTAAAGGCATTTATAATAA
CATTAAAAATTTTGTTAGATTTCAACTGAGCACGAGTATAGCAGCATTAACTTTAATCTCATTG
GCTACGTTAATGAACTTTCCTAACCCTCTCAATGCAATGCAGATTTTGTGGATCAATATTATAA
TGGATGGACCCCCAGCTCAGAGCCTTGGAGTAGAGCCAGTGGATAAAGATGTCATTCGAAAACC
CCCTCGGAACTGGAAGGACAGCATTTTGACAAAAAACTTGATCCTTAAAATACTTGTTTCATCA
ATAATCATTGTCTGTGGGACTTTGTTTGTCTTCTGGCGAGAGCTTCGAGACAATGTGATAACAC
CCCGAGACACAACAATGACTTTCACTTGCTTCGTGTTTTTTGATATGTTCAATGCACTGAGTTC
CAGATCTCAGACTAAGTCTGTGTTTGAGATTGGACTCTGCAGTAATAAGATGTTCTGCTATGCG
GTTCTTGGATCCATCATGGGGCAGTTGCTTGTTATCTACTTCCCGCCTCTGCAGAAGGTTTTTC
AGACCGAGAGCCTCAGTATTCTGGATCTGTTGTTTCTTTTGGGTCTCACTTCATCAGTGTGCAT
TGTGTCTGAAATTATAAAGAAGGTTGAAAGGAGCAGGGAAAAGACTCAGAAGAACGCTACTTCA
ACACCATCGTCTTTTCTTGAAGTATGATGCATATTGCATTTTTTTTTTCATTTGCAAACTAGGA
ATTGCAGTCTGGGAATCATTTAGAAGGGCAAGTTCAAGAGGATAATGAAGATTTAAGGACTTTT
AAACTTTCCATTGACTAAAAATGACCATTAATGTTAAAGACTTGATTTGAACCTTGTTGGTAGT
CCCAAATGAAATTATGCAACTTTGAATAACACGTTCCTTGATTTGAATTGGCTTTTGCAATCGA
TTGGAACTTCAACATATGGTCAAGTACTGAATTAAAAAAGTACAAAAGGCAAAACGTGAACACC
TTCTGCACTTAGAGTTCTAATGTACAAATACACTATCTGTCTTAGATGGATATAAATATTTTTT
TTATTTTTAAATATTGTACTATTTATGGTTGTGGGGCTTTCTTACTAATACACTCAATAAATGC
ACTCAGTCATTTCAAAGGCATTCTATTTGGTTTAGAAATTGCCAGGAGTGCCATATTTCAGCTA
CCATGTTTCCTTTTTCCTGCAATGTACGCAAATGATACCTTGTGCTACCATTTTTATATTTCAA
GTTTTTTATTTTTTATTTTTGCACAGGATGTGACCACTGTCTAATCACTGTTCTTTTTTTTTGT
GACTGAAAAGCATATACTGCAATTGAAGTAAATGTTTGCTCTTCTTAGTAAGTGTACATGGTTG
TTTTGGTTTTTTGTAGTGGTTTTCCACAGAGGTGTGAGTCTTTGACCTAGCAGGATTAGTTCAG
GCTGTTGTTGCATTACAGTTAGAGTAATTGTACTTAACACAGTCAAAGAGTCAAAAACAACAAA
GGCTGGATGGAATTTCAAACAGACTATGTTAACACGTCCTTGTTTAGGTTAATACAGTTCTACT
TTGTCAGTGTCATCTTGTCATTTCTTCTTTATAAATCAAACACTTCAGCTAAATAATTGACCTT
TATTACTGTTTCATATTTGTATTTTTAAGTCTATTTCTTAGAGAGTATAGACTACCATACTTAG
AAAATCAAAAGTCCCAAACTCAGAGAGATAGGACATGAACCAGGGTGTCCATCAGAAGATCCTG
TGCAGGCCTTGCTCCTCCGAATCCTCTAGGCAGCCGCTTTGGCCTAGATTGTAGCACAACCCTG
AGTCTGTCCCTTCTGCCGTTTGTTGGGATCCGTCTTCTTCTTTTGGTATGCTTGGGAAATAGAT
GGATTTGCTTTGTGTAAACCATCAGTTTTTATAAGAGCTTGACAAAATAAAGGTAAGTGTTGAA
TCTTGTATTTCATAAACTGTCAGAATTAACTGTTCTGAGCTTGTTCAATATTACTGGTGAGTGT
TAACGCTGCTGCGCTGTCGTTGATAGGAGAACTCTGTTGTCTGAGTCTGTACTACTGAAGCATG
AACGTAAGGAGCCAGATGTCTGACTTTGTCTTAATCTCTCAGGCTCAACTGTCAGTGTACATTG
TTCTGTCTCATTAGGTGGGACGTGAGGTCACTGTCAACCAACTCATAGAGGTTTGATGTCTCAT
AGCAAAATTTTATAATGGTTTTTTACATTCTGTTCCAAACTTGAAAACTACATATTAAGTGCAT
ATTCAGTCTTGTTTGTTTTACAGTAGAGGTTGAGAATATGACTCATGAAATGAATGTGCCTATC
TTTTCACTTGGTATTGAACTATAAAAATAAAGTGAGTTTTTCATAAGTTCAAAAAAAAAAAAAA
AAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_039080729 ⟹ XP_038936657

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	8	114,913,551 - 115,034,706 (-)	NCBI
mRatBN7.2	8	106,034,777 - 106,155,854 (-)	NCBI

RefSeq Acc Id:

XM_063264804 ⟹ XP_063120874

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	8	114,913,551 - 115,009,508 (-)	NCBI

RefSeq Acc Id:

XM_063264805 ⟹ XP_063120875

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	8	114,913,551 - 115,011,375 (-)	NCBI

RefSeq Acc Id:

XM_063264806 ⟹ XP_063120876

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	8	114,913,551 - 115,009,508 (-)	NCBI

RefSeq Acc Id:

XM_063264807 ⟹ XP_063120877

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	8	114,913,551 - 115,011,375 (-)	NCBI

RefSeq Acc Id:

XM_063264808 ⟹ XP_063120878

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	8	114,913,551 - 115,011,375 (-)	NCBI

RefSeq Acc Id:

XM_063264809 ⟹ XP_063120879

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	8	114,913,551 - 115,010,087 (-)	NCBI

RefSeq Acc Id:

XR_005487741

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	8	114,913,551 - 115,034,706 (-)	NCBI
mRatBN7.2	8	106,034,777 - 106,155,853 (-)	NCBI

RefSeq Acc Id:

XR_010053920

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	8	114,913,551 - 115,034,706 (-)	NCBI

RefSeq Acc Id:

XR_010053921

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	8	114,913,551 - 115,009,508 (-)	NCBI

RefSeq Acc Id:

XR_010053922

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	8	114,913,551 - 115,009,508 (-)	NCBI

RefSeq Acc Id:

XR_010053923

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	8	114,913,551 - 115,011,375 (-)	NCBI

RefSeq Acc Id:

XR_010053924

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	8	114,913,551 - 115,010,087 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_571982	(Get FASTA)	NCBI Sequence Viewer
	XP_038936657	(Get FASTA)	NCBI Sequence Viewer
	XP_063120874	(Get FASTA)	NCBI Sequence Viewer
	XP_063120875	(Get FASTA)	NCBI Sequence Viewer
	XP_063120876	(Get FASTA)	NCBI Sequence Viewer
	XP_063120877	(Get FASTA)	NCBI Sequence Viewer
	XP_063120878	(Get FASTA)	NCBI Sequence Viewer
	XP_063120879	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAA73341	(Get FASTA)	NCBI Sequence Viewer
	AAA73342	(Get FASTA)	NCBI Sequence Viewer
	AAH86994	(Get FASTA)	NCBI Sequence Viewer
	EDL77343	(Get FASTA)	NCBI Sequence Viewer
	EDL77344	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000085864
	ENSRNOP00000088420
	ENSRNOP00000096296
GenBank Protein	Q64566	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_571982 ⟸ NM_131907

- UniProtKB:

Q64567 (UniProtKB/Swiss-Prot), Q64566 (UniProtKB/Swiss-Prot), Q5PQW5 (UniProtKB/TrEMBL), A6I2N4 (UniProtKB/TrEMBL), A0A8I6GM06 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MKVARFQKIPNVENETMIPVLTSKRASELAVSEVAGLLQADLQNGLNKSEVSHRRAFHGWNEFD
ISEDEPLWKKYISQFKNPLIMLLLASAVISVLMRQFDDAVSITVAILIVVTVAFVQEYRSEKSL
EELSKLVPPECHCVREGKLEHTLARDLVPGDTVCLSVGDRVPADLRLFEAVDLSIDESSLTGET
TPCSKVTAPQPAATNGDLASRSNIAFMGTLVRCGKAKGIVIGTGENSEFGEVFKMMQAEEAPKT
PLQKSMDLLGKQLSFYSFGIIGIIMLVGWLLGKDILEMFTISVSLAVAAIPEGLPIVVTVTLAL
GVMRMVKKRAIVKKLPIVETLGCCNVICSDKTGTLTKNEMTVTHILTSDGLHAEVTGVGYNQFG
EVIVDGDVVHGFYNPAVSRIVEAGCVCNDAVIRNNTLMGKPTEGALIALAMKMGLDGLQQDYIR
KAEYPFSSEQKWMAVKCVHRTQQDRPEICFMKGAYEQVIKYCTTYNSKGQTLALTQQQRDLYQQ
EKAQMGSAGLRVLALASGPDLGQLTFLGLVGIIDPPRTGVKEAVTTLIASGVSIKMITGDSQET
AIAIASRLGLYSKTSQSVSGEEVDTMEVQHLSQIVPKVAVFYRASPRHKMKIIKSLQKNGSVVA
MTGDGVNDAVALKAADIGVAMGQTGTDVCKEAADMILVDDDFQTIMSAIEEGKGIYNNIKNFVR
FQLSTSIAALTLISLATLMNFPNPLNAMQILWINIIMDGPPAQSLGVEPVDKDVIRKPPRNWKD
SILTKNLILKILVSSIIIVCGTLFVFWRELRDNVITPRDTTMTFTCFVFFDMFNALSSRSQTKS
VFEIGLCSNKMFCYAVLGSIMGQLLVIYFPPLQKVFQTESLSILDLLFLLGLTSSVCIVSEIIK
KVERSREKTQKNATSTPSSFLEV

hide sequence

Ensembl Acc Id:

ENSRNOP00000018175 ⟸ ENSRNOT00000018175

Ensembl Acc Id:

ENSRNOP00000045953 ⟸ ENSRNOT00000045087

RefSeq Acc Id:	XP_038936657 ⟸ XM_039080729
- Peptide Label:	isoform X1
- UniProtKB:	A0A8I6G9F5 (UniProtKB/TrEMBL), A6I2N3 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSRNOP00000097217 ⟸ ENSRNOT00000119741

Ensembl Acc Id:

ENSRNOP00000089204 ⟸ ENSRNOT00000112729

Ensembl Acc Id:

ENSRNOP00000096296 ⟸ ENSRNOT00000095638

Ensembl Acc Id:

ENSRNOP00000088420 ⟸ ENSRNOT00000097914

Ensembl Acc Id:

ENSRNOP00000076661 ⟸ ENSRNOT00000099084

Ensembl Acc Id:

ENSRNOP00000085864 ⟸ ENSRNOT00000103991

Ensembl Acc Id:

ENSRNOP00000083761 ⟸ ENSRNOT00000102340

RefSeq Acc Id:	XP_063120878 ⟸ XM_063264808
- Peptide Label:	isoform X3
- UniProtKB:	Q64567 (UniProtKB/Swiss-Prot), Q64566 (UniProtKB/Swiss-Prot)

RefSeq Acc Id:	XP_063120875 ⟸ XM_063264805
- Peptide Label:	isoform X2
- UniProtKB:	A0A8I5Y5G2 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063120877 ⟸ XM_063264807
- Peptide Label:	isoform X3
- UniProtKB:	Q64567 (UniProtKB/Swiss-Prot), Q64566 (UniProtKB/Swiss-Prot)

RefSeq Acc Id:	XP_063120879 ⟸ XM_063264809
- Peptide Label:	isoform X4
- UniProtKB:	Q64567 (UniProtKB/Swiss-Prot), Q64566 (UniProtKB/Swiss-Prot), A0A8I6A6R2 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063120876 ⟸ XM_063264806
- Peptide Label:	isoform X3
- UniProtKB:	Q64567 (UniProtKB/Swiss-Prot), Q64566 (UniProtKB/Swiss-Prot)

RefSeq Acc Id:	XP_063120874 ⟸ XM_063264804
- Peptide Label:	isoform X2
- UniProtKB:	A0A8I5Y5G2 (UniProtKB/TrEMBL)

Protein Domains

Cation-transporting P-type ATPase C-terminal Cation-transporting P-type ATPase N-terminal

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q64566-F1-model_v2	AlphaFold	Q64566	1-919	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:621311	AgrOrtholog
BioCyc Gene	G2FUF-29272	BioCyc
Ensembl Genes	ENSRNOG00000013305	Ensembl, ENTREZGENE
Ensembl Transcript	ENSRNOT00000095638	ENTREZGENE
	ENSRNOT00000097914	ENTREZGENE
	ENSRNOT00000103991	ENTREZGENE
Gene3D-CATH	3.40.1110.10	UniProtKB/Swiss-Prot
	3.40.50.1000	UniProtKB/Swiss-Prot
	Calcium-transporting ATPase, cytoplasmic transduction domain A	UniProtKB/Swiss-Prot
	Calcium-transporting ATPase, transmembrane domain	UniProtKB/Swiss-Prot
IMAGE_CLONE	IMAGE:7106233	IMAGE-MGC_LOAD
InterPro	ATPase_P-typ_cation-transptr_C	UniProtKB/Swiss-Prot
	ATPase_P-typ_cation-transptr_N	UniProtKB/Swiss-Prot
	ATPase_P-typ_cyto_dom_N	UniProtKB/Swiss-Prot
	ATPase_P-typ_P_site	UniProtKB/Swiss-Prot
	ATPase_P-typ_TM_dom_sf	UniProtKB/Swiss-Prot
	ATPase_P-typ_transduc_dom_A_sf	UniProtKB/Swiss-Prot
	HAD-like_sf	UniProtKB/Swiss-Prot
	HAD_sf	UniProtKB/Swiss-Prot
	P-type_ATPase_IIA_PMR1	UniProtKB/Swiss-Prot
	P_typ_ATPase	UniProtKB/Swiss-Prot
	P_typ_ATPase_HD_dom	UniProtKB/Swiss-Prot
MGC_CLONE	MGC:93231	IMAGE-MGC_LOAD
NCBI Gene	170699	ENTREZGENE
PANTHER	CALCIUM-TRANSPORTING ATPASE	UniProtKB/Swiss-Prot
Pfam	Cation_ATPase	UniProtKB/Swiss-Prot
	Cation_ATPase_C	UniProtKB/Swiss-Prot
	Cation_ATPase_N	UniProtKB/Swiss-Prot
	E1-E2_ATPase	UniProtKB/Swiss-Prot
PhenoGen	Atp2c1	PhenoGen
PRINTS	CATATPASE	UniProtKB/Swiss-Prot
	HATPASE	UniProtKB/Swiss-Prot
PROSITE	ATPASE_E1_E2	UniProtKB/Swiss-Prot
RatGTEx	ENSRNOG00000013305	RatGTEx
SMART	Cation_ATPase_N	UniProtKB/Swiss-Prot
Superfamily-SCOP	SSF56784	UniProtKB/Swiss-Prot
	SSF81653	UniProtKB/Swiss-Prot
	SSF81660	UniProtKB/Swiss-Prot
	SSF81665	UniProtKB/Swiss-Prot
UniProt	A0A8I5Y5G2	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6A4Z3_RAT	UniProtKB/TrEMBL
	A0A8I6A662_RAT	UniProtKB/TrEMBL
	A0A8I6A6R2	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6B5G9_RAT	UniProtKB/TrEMBL
	A0A8I6G9F5	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6GM06	ENTREZGENE, UniProtKB/TrEMBL
	A6I2N3	ENTREZGENE, UniProtKB/TrEMBL
	A6I2N4	ENTREZGENE, UniProtKB/TrEMBL
	AT2C1_RAT	UniProtKB/Swiss-Prot
	F1M281_RAT	UniProtKB/TrEMBL
	F1M9B5_RAT	UniProtKB/TrEMBL
	Q5PQW5	ENTREZGENE
	Q64566	ENTREZGENE
	Q64567	ENTREZGENE
UniProt Secondary	Q64567	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2021-03-09	Atp2c1	ATPase secretory pathway Ca2+ transporting 1	LOC103690457	uncharacterized LOC103690457	Data merged from RGD:9244782	737654	PROVISIONAL
2016-02-17	Atp2c1	ATPase secretory pathway Ca2+ transporting 1	Atp2c1	ATPase, Ca++ transporting, type 2C, member 1	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2014-08-25	LOC103690457	uncharacterized LOC103690457			Symbol and Name status set to provisional	70820	PROVISIONAL
2008-06-27	Atp2c1	ATPase, Ca++ transporting, type 2C, member 1	Atp2c1	ATPase, Ca++-sequestering	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2004-02-26	Atp2c1	ATPase, Ca++-sequestering			Symbol and Name status set to approved	625702	APPROVED
2002-08-07	Atp2c1	ATPase, Ca++-sequestering			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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