Ttn (titin) - Rat Genome Database

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Gene: Ttn (titin) Rattus norvegicus
Analyze
Symbol: Ttn
Name: titin
RGD ID: 621114
Description: Predicted to enable several functions, including cytoskeletal protein binding activity; enzyme binding activity; and protein kinase activity. Predicted to be a structural constituent of muscle. Involved in sarcomere organization. Located in I band. Biomarker of myocardial infarction. Human ortholog(s) of this gene implicated in intrinsic cardiomyopathy (multiple) and myopathy (multiple). Orthologous to human TTN (titin); PARTICIPATES IN dilated cardiomyopathy pathway; hypertrophic cardiomyopathy pathway; INTERACTS WITH 3,3',5-triiodo-L-thyronine; acetylleucyl-leucyl-norleucinal; acrylamide.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: titin protein homolog
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: Ttnem1Sage   Ttnem2Sage  
Genetic Models: F344-Ttnem2Sage F344-Ttnem1Sage
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2361,652,432 - 61,924,912 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl361,652,439 - 61,924,741 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.0363,565,160 - 63,837,815 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0370,138,896 - 70,408,647 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4359,404,023 - 59,665,308 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1359,490,644 - 59,514,338 (-)NCBI
Celera361,137,881 - 61,409,292 (-)NCBICelera
Cytogenetic Map3q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
arrhythmogenic right ventricular cardiomyopathy  (ISO)
arrhythmogenic right ventricular dysplasia 1  (ISO)
arrhythmogenic right ventricular dysplasia 9  (ISO)
atrial fibrillation  (ISO)
autosomal recessive centronuclear myopathy  (ISO)
autosomal recessive limb-girdle muscular dystrophy  (ISO)
autosomal recessive limb-girdle muscular dystrophy type 2J  (ISO,ISS)
Brugada syndrome  (ISO)
cardiac amyloidosis  (ISO)
cardiomyopathy  (ISO)
centronuclear myopathy  (ISO)
cerebral palsy  (ISO)
clubfoot  (ISO)
congenital muscular dystrophy  (ISO)
congenital myopathy  (ISO)
congenital myopathy 1B  (ISO)
congenital myopathy 5  (ISO)
congenital structural myopathy  (ISO)
congestive heart failure  (ISO)
coronary artery disease  (ISO)
Diastolic Dysfunction  (ISO)
dilated cardiomyopathy  (ISO)
dilated cardiomyopathy 1A  (ISO)
dilated cardiomyopathy 1B  (ISO)
dilated cardiomyopathy 1G  (ISO,ISS)
dilated cardiomyopathy 1H  (ISO)
dilated cardiomyopathy 1S  (ISO)
Dilated Cardiomyopathy with Left Ventricular Noncompaction  (ISO)
distal myopathy  (ISO)
Dwarfism  (ISO)
dystonia 16  (ISO)
Failure to Thrive  (ISO)
Familial Amyloid Polyneuropathies  (ISO)
familial hypertrophic cardiomyopathy  (ISO)
Gaucher's disease  (ISO)
Gaucher's disease type I  (ISO)
genetic disease  (ISO)
Heart Block  (ISO)
hypertrophic cardiomyopathy  (ISO)
hypertrophic cardiomyopathy 1  (ISO)
hypertrophic cardiomyopathy 9  (ISO)
Left Ventricular Hypertrophy  (ISO)
left ventricular noncompaction  (ISO)
Left Ventricular Noncompaction 2  (ISO)
leukocyte adhesion deficiency 1  (ISO)
limb-girdle muscular dystrophy  (ISO)
long QT syndrome  (ISO)
mitral valve prolapse  (ISO)
Muscle Hypotonia  (ISO)
Muscle Weakness  (ISO)
muscular disease  (ISO)
muscular dystrophy  (ISO)
myocardial infarction  (IEP)
Myocardial Ischemia  (IDA)
myofibrillar myopathy 1  (ISO)
myofibrillar myopathy 9  (ISO)
myopathy  (ISO)
neuromuscular disease  (ISO)
orofacial cleft 1  (ISO)
restrictive cardiomyopathy  (ISO)
speech disorder  (ISO)
Sudden Cardiac Death  (ISO)
sudden infant death syndrome  (ISO)
Sudden Unexpected Nocturnal Death Syndrome  (ISO)
Supraventricular Tachycardia  (ISO)
Syncope  (ISO)
systolic heart failure  (ISO)
third-degree atrioventricular block  (ISO)
tibial muscular dystrophy  (ISO,ISS)
transthyretin amyloidosis  (ISO)
Ventricular Fibrillation  (ISO)
Ventricular Premature Complexes  (ISO)
Ventricular Tachycardia  (ISO)
Wolff-Parkinson-White syndrome  (ISO)
X-linked Emery-Dreifuss muscular dystrophy 6  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (ISO)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
3,3',5-triiodo-L-thyronine  (EXP)
3,4-methylenedioxymethamphetamine  (ISO)
3-phenylprop-2-enal  (ISO)
4,4'-sulfonyldiphenol  (ISO)
acetylleucyl-leucyl-norleucinal  (EXP)
acrylamide  (EXP)
aflatoxin B1  (ISO)
ammonium chloride  (EXP)
atrazine  (EXP)
benzo[a]pyrene  (ISO)
benzo[b]fluoranthene  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
Botulinum toxin type A  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
cantharidin  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
ciguatoxin CTX1B  (ISO)
copper(II) sulfate  (ISO)
coumarin  (ISO)
cylindrospermopsin  (ISO)
dexamethasone  (ISO)
dextran sulfate  (ISO)
dibutyl phthalate  (EXP)
dimethylarsinic acid  (ISO)
dioxygen  (ISO)
diuron  (ISO)
doxorubicin  (EXP,ISO)
entinostat  (ISO)
glyphosate  (EXP)
hydrogen cyanide  (ISO)
hydrogen peroxide  (ISO)
ivermectin  (ISO)
lipopolysaccharide  (ISO)
LY294002  (EXP)
methamphetamine  (ISO)
methylmercury chloride  (ISO)
microcystin-LR  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
N-nitrosodiethylamine  (EXP)
nickel atom  (ISO)
nitrogen dioxide  (ISO)
O-methyleugenol  (ISO)
paracetamol  (ISO)
phenethyl caffeate  (EXP)
pioglitazone  (ISO)
pirinixic acid  (ISO)
potassium cyanide  (ISO)
potassium dichromate  (ISO)
propiconazole  (ISO)
quercetin  (ISO)
resveratrol  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
serpentine asbestos  (ISO)
sodium arsenite  (ISO)
sodium fluoride  (ISO)
spermine  (ISO)
sulforaphane  (ISO)
sunitinib  (ISO)
T-2 toxin  (ISO)
thalidomide  (ISO)
theophylline  (ISO)
titanium dioxide  (ISO)
triclosan  (ISO)
triptonide  (ISO)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Detection of myofibrillar proteins using a step gradient minigel with an ambiguous interface. Chen SP, etal., Anal Biochem. 2005 Mar 15;338(2):270-7.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Profiles of connectin (titin) in atrophied soleus muscle induced by unloading of rats. Goto K, etal., J Appl Physiol. 2003 Mar;94(3):897-902. Epub 2002 Oct 11.
4. Passive stiffness changes caused by upregulation of compliant titin isoforms in human dilated cardiomyopathy hearts. Makarenko I, etal., Circ Res. 2004 Oct 1;95(7):708-16. Epub 2004 Sep 2.
5. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
6. Titin isoform switch in ischemic human heart disease. Neagoe C, etal., Circulation. 2002 Sep 10;106(11):1333-41.
7. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
8. Antisense oligonucleotide experiments elucidate the essential role of titin in sarcomerogenesis in adult rat cardiomyocytes in long-term culture. Person V, etal., J Cell Sci 2000 Nov;113 Pt 21:3851-9.
9. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
10. GOA pipeline RGD automated data pipeline
11. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
12. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
13. Structural analysis of the titin gene in hypertrophic cardiomyopathy: identification of a novel disease gene. Satoh M, etal., Biochem Biophys Res Commun. 1999 Aug 27;262(2):411-7.
14. Titin-truncating variants affect heart function in disease cohorts and the general population. Schafer S, etal., Nat Genet. 2016 Nov 21. doi: 10.1038/ng.3719.
Additional References at PubMed
PMID:7607248   PMID:7896840   PMID:9375787   PMID:9501083   PMID:9548712   PMID:9642272   PMID:9804419   PMID:9817758   PMID:11717165   PMID:11846417   PMID:11945023   PMID:12079354  
PMID:12432079   PMID:12651156   PMID:12785098   PMID:14676206   PMID:14988228   PMID:15138196   PMID:15454261   PMID:15582318   PMID:15688246   PMID:15802564   PMID:16115818   PMID:16407954  
PMID:16470334   PMID:16481394   PMID:16491431   PMID:16679402   PMID:16702235   PMID:16962974   PMID:17069849   PMID:17360664   PMID:17436058   PMID:18096819   PMID:18166625   PMID:18310072  
PMID:18519573   PMID:18528655   PMID:18765796   PMID:19056867   PMID:19150150   PMID:19260067   PMID:19850579   PMID:20799659   PMID:20968071   PMID:21041693   PMID:21703204   PMID:22105831  
PMID:22140043   PMID:22466703   PMID:23283722   PMID:23414517   PMID:23764881   PMID:24269766   PMID:25077715   PMID:25152160   PMID:25264194   PMID:25509861   PMID:26394485   PMID:26858417  
PMID:28676430   PMID:30063764   PMID:30715350   PMID:32889570   PMID:33368047   PMID:33805770   PMID:34668430   PMID:34681770   PMID:35762193  


Genomics

Comparative Map Data
Ttn
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2361,652,432 - 61,924,912 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl361,652,439 - 61,924,741 (-)EnsemblmRatBN7.2 Ensembl
Rnor_6.0363,565,160 - 63,837,815 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0370,138,896 - 70,408,647 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4359,404,023 - 59,665,308 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1359,490,644 - 59,514,338 (-)NCBI
Celera361,137,881 - 61,409,292 (-)NCBICelera
Cytogenetic Map3q24NCBI
TTN
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382178,525,989 - 178,807,423 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2178,525,989 - 178,830,802 (-)EnsemblGRCh38hg38GRCh38
GRCh372179,390,716 - 179,672,150 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362179,098,962 - 179,380,395 (-)NCBINCBI36Build 36hg18NCBI36
Celera2172,993,600 - 173,266,525 (-)NCBICelera
Cytogenetic Map2q31.2NCBI
HuRef2171,261,156 - 171,540,118 (-)NCBIHuRef
CHM1_12179,396,760 - 179,678,208 (-)NCBICHM1_1
T2T-CHM13v2.02179,008,783 - 179,290,485 (-)NCBIT2T-CHM13v2.0
Ttn
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39276,534,324 - 76,812,901 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl276,534,324 - 76,812,891 (-)EnsemblGRCm39 Ensembl
GRCm38276,703,980 - 76,982,557 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl276,703,980 - 76,982,547 (-)EnsemblGRCm38mm10GRCm38
MGSCv37276,542,041 - 76,820,604 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36276,504,823 - 76,783,386 (-)NCBIMGSCv36mm8
Celera278,365,659 - 78,644,178 (-)NCBICelera
Cytogenetic Map2C3NCBI
cM Map245.13NCBI
Ttn
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495540318,057,344 - 18,328,389 (+)NCBIChiLan1.0ChiLan1.0
TTN
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan12B81,187,144 - 81,467,889 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B65,783,512 - 66,064,618 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B183,487,352 - 183,767,268 (-)NCBIpanpan1.1PanPan1.1panPan2
TTN
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13622,146,870 - 22,417,858 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3622,147,824 - 22,417,826 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3622,165,230 - 22,439,415 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03622,290,643 - 22,564,715 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3622,291,570 - 22,564,719 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13622,399,838 - 22,673,559 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03622,362,753 - 22,636,976 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03622,479,043 - 22,752,940 (-)NCBIUU_Cfam_GSD_1.0
Ttn
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303139,179,523 - 139,445,548 (-)NCBIHiC_Itri_2
SpeTri2.0NW_0049365097,733,426 - 7,999,503 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TTN
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.11584,226,953 - 84,501,320 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21593,758,133 - 93,780,787 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TTN
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11064,074,994 - 64,379,055 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1064,076,021 - 64,347,205 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666040135,225,819 - 135,499,926 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ttn
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624844484,593 - 760,155 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Ttn
1053 total Variants

QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2290452Scl56Serum cholesterol level QTL 562.26blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)3191609953Rat
1358905Hrtrt17Heart rate QTL 175.90.000014heart pumping trait (VT:2000009)heart rate (CMO:0000002)31086191289878372Rat
1358885Bp251Blood pressure QTL 2513.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)314489145121056321Rat
1358888Bp264Blood pressure QTL 2644.43arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)314489145121056321Rat
2298542Neuinf11Neuroinflammation QTL 113.9nervous system integrity trait (VT:0010566)spinal cord complement component 1, q subcomponent, B chain mRNA level (CMO:0002126)31500542276927699Rat
631676Cm8Cardiac mass QTL 87.030.0001aorta mass (VT:0002845)aorta weight (CMO:0000076)31695470861954708Rat
10450804Scl70Serum cholesterol level QTL 704.70.001blood LDL cholesterol amount (VT:0000181)blood low density lipoprotein cholesterol level (CMO:0000053)32071409065714090Rat
10450794Scl69Serum cholesterol level QTL 696.30.001blood LDL cholesterol amount (VT:0000181)blood low density lipoprotein cholesterol level (CMO:0000053)32071409065714090Rat
2302055Pia30Pristane induced arthritis QTL 303.50.001blood autoantibody amount (VT:0003725)serum immunoglobulin M-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002111)32793691972936919Rat
9590286Uminl1Urine mineral level QTL 13.50.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)32824968773249687Rat
8694196Abfw2Abdominal fat weight QTL 216.580.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)32824968773249687Rat
8694386Bw159Body weight QTL 1594.520.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)32824968773249687Rat
8552950Pigfal12Plasma insulin-like growth factor 1 level QTL 127.3blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)32824968773249687Rat
9590136Scort3Serum corticosterone level QTL 323.370.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)32824968773249687Rat
2303593Gluco46Glucose level QTL 463blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)32846857173468571Rat
1354590Despr11Despair related QTL 110.000031locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)32846857173468571Rat
737818Hcar12Hepatocarcinoma resistance QTL 122.6liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)329463235118376539Rat
61419Cia11Collagen induced arthritis QTL 115.6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)33035677398535386Rat
61356Bp37Blood pressure QTL 373blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)33068464275684642Rat
631647Bp122Blood pressure QTL 1226.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)33068464275684642Rat
70216Cm14Cardiac mass QTL 142.1heart mass (VT:0007028)heart wet weight (CMO:0000069)331172320163586636Rat
11565451Bw177Body weight QTL 1770.002body mass (VT:0001259)body weight (CMO:0000012)33142640370668733Rat
11565452Kidm57Kidney mass QTL 570.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)33142640370668733Rat
12879866Cm94Cardiac mass QTL 940.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)33142640370668733Rat
12879867Cm95Cardiac mass QTL 950.047heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)33142640370668733Rat
12879868Am6Aortic mass QTL 60.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)33142640370668733Rat
2301400Cm68Cardiac mass QTL 680.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)33142640370668733Rat
1354589Bw31Body weight QTL 313.3body mass (VT:0001259)body weight (CMO:0000012)33370334778196190Rat
1354604Bw36Body weight QTL 362.9body mass (VT:0001259)body weight (CMO:0000012)333703347104104347Rat
1358362Srcrt2Stress Responsive Cort QTL 22.78blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)338192233133483320Rat
738019Anxrr10Anxiety related response QTL 103.9exploratory behavior trait (VT:0010471)number of entries into a discrete space in an experimental apparatus (CMO:0000960)33851780383517803Rat
2302276Bw82Body weight QTL 824.32body mass (VT:0001259)body weight (CMO:0000012)33945463762951183Rat
1331777Bw24Body weight QTL 243.503body mass (VT:0001259)body weight (CMO:0000012)33945463789115240Rat
1331795Rf30Renal function QTL 303.708urine potassium amount (VT:0010539)urine potassium level (CMO:0000128)33945463789115240Rat
1354597Kidm13Kidney mass QTL 132.9kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)341874578104104347Rat
2301970Bw81Body weight QTL 815.19body mass (VT:0001259)body weight (CMO:0000012)341874578155617519Rat
2301971Cm71Cardiac mass QTL 714.63heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)341874578155617519Rat
1300178Hrtrt4Heart rate QTL 43.74heart pumping trait (VT:2000009)heart rate (CMO:0000002)34382736490905114Rat
1581503Cm58Cardiac mass QTL 582.70.05heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)343827364121056321Rat
1559282Emca5Estrogen-induced mammary cancer QTL 53.9mammary gland integrity trait (VT:0010552)percentage of study population developing mammary tumors during a period of time (CMO:0000948)343827364169034231Rat
2292591Esta4Estrogen-induced thymic atrophy QTL 4thymus mass (VT:0004954)thymus wet weight (CMO:0000855)347233211147415807Rat
1358186Ept2Estrogen-induced pituitary tumorigenesis QTL 28.3pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)347233430110362260Rat
2292613Ept16Estrogen-induced pituitary tumorigenesis QTL 168.3pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)347233430110362260Rat
631665Bw8Body weight QTL 85.5body mass (VT:0001259)body weight (CMO:0000012)350437042119183768Rat
724523Tsu1Thymus enlargement suppressive QTL 13.84thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)350437504115638231Rat
1582249Bw77Body weight QTL 773.20.0025epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)35318459364655484Rat
1582218Bw74Body weight QTL 743.90.0021body mass (VT:0001259)body weight (CMO:0000012)353184593115665732Rat
1582238Bw68Body weight QTL 683.20.0064body mass (VT:0001259)body weight (CMO:0000012)353184593115665732Rat
1582239Epfw1Epididymal fat weight QTL 14.50.0006epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)353184593115665732Rat
61377Edpm3Estrogen-dependent pituitary mass QTL 37.050.038pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)35318469289878207Rat
731180Bp152Blood pressure QTL 1520.03arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)35378111291609953Rat
731180Bp152Blood pressure QTL 1520.03arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)35378111291609953Rat
731180Bp152Blood pressure QTL 1520.03arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)35378111291609953Rat
1581568Rf53Renal function QTL 53urine total protein amount (VT:0000032)urine protein excretion rate to body weight ratio (CMO:0001099)356395968161299569Rat
8662816Vetf4Vascular elastic tissue fragility QTL 44renal artery integrity trait (VT:0010642)number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563)359242096157323038Rat
1300111Rf12Renal function QTL 123.78renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)361017749121056321Rat
631200Cm25Cardiac mass QTL 254.80.0001heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)36113434889115068Rat

Markers in Region
RH98821  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2361,675,712 - 61,675,852 (+)MAPPERmRatBN7.2
Rnor_6.0363,588,441 - 63,588,580NCBIRnor6.0
Rnor_5.0370,162,177 - 70,162,316UniSTSRnor5.0
RGSC_v3.4359,427,737 - 59,427,876UniSTSRGSC3.4
Celera361,161,160 - 61,161,299UniSTS
Cytogenetic Map3q23UniSTS
RH131516  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2361,862,090 - 61,862,296 (+)MAPPERmRatBN7.2
Rnor_6.0363,775,710 - 63,775,915NCBIRnor6.0
Rnor_5.0370,346,833 - 70,347,038UniSTSRnor5.0
RGSC_v3.4359,604,915 - 59,605,120UniSTSRGSC3.4
Celera361,346,433 - 61,346,638UniSTS
Cytogenetic Map3q23UniSTS
RH137063  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2361,652,435 - 61,652,611 (+)MAPPERmRatBN7.2
Rnor_6.0363,565,164 - 63,565,339NCBIRnor6.0
Rnor_5.0370,138,900 - 70,139,075UniSTSRnor5.0
RGSC_v3.4359,404,460 - 59,404,635UniSTSRGSC3.4
Celera361,137,885 - 61,138,060UniSTS
Cytogenetic Map3q23UniSTS
MARC_23497-23498:1027358865:1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2361,704,263 - 61,704,930 (+)MAPPERmRatBN7.2
Rnor_6.0363,617,472 - 63,618,138NCBIRnor6.0
Rnor_5.0370,189,953 - 70,190,619UniSTSRnor5.0
Celera361,189,633 - 61,190,299UniSTS
Cytogenetic Map3q23UniSTS
D2S1570E  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2361,724,050 - 61,724,240 (+)MAPPERmRatBN7.2
Rnor_6.0363,636,859 - 63,637,048NCBIRnor6.0
Rnor_5.0370,209,340 - 70,209,529UniSTSRnor5.0
RGSC_v3.4359,465,671 - 59,465,860UniSTSRGSC3.4
Celera361,209,377 - 61,209,566UniSTS
Cytogenetic Map3q23UniSTS


Genetic Models
This gene Ttn is modified in the following models/strains:


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_032068 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017592328 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017600986 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106384 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106385 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106386 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106387 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106388 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106389 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106390 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106391 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106393 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106394 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106395 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106396 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106397 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106398 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106399 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106400 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106401 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106402 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106403 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106404 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106405 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106406 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106407 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106408 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106409 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106410 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106411 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106412 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106413 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106414 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106415 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106416 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106417 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106418 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106419 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106420 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106421 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106422 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106423 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106424 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106425 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106426 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106427 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106428 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106429 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106430 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106431 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106432 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106433 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039106434 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AF059344 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF525411 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF525412 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ401157 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY429596 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY429597 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY429598 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY429599 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY429600 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY429601 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY434474 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ214588 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ214599 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ214796 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ215422 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JACYVU010000115 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L38717 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U82224 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U89530 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U89531 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSRNOT00000030978   ⟹   ENSRNOP00000033967
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl361,907,065 - 61,924,741 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000101577   ⟹   ENSRNOP00000081880
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl361,652,439 - 61,924,741 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000107188   ⟹   ENSRNOP00000084099
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl361,899,657 - 61,924,741 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000108121   ⟹   ENSRNOP00000086880
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl361,862,276 - 61,924,741 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000114553   ⟹   ENSRNOP00000082190
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl361,652,439 - 61,924,741 (-)Ensembl
RefSeq Acc Id: XM_039106384   ⟹   XP_038962312
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2361,652,432 - 61,924,912 (-)NCBI
RefSeq Acc Id: XM_039106385   ⟹   XP_038962313
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2361,652,432 - 61,924,912 (-)NCBI
RefSeq Acc Id: XM_039106386   ⟹   XP_038962314
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2361,652,432 - 61,924,912 (-)NCBI
RefSeq Acc Id: XM_039106387   ⟹   XP_038962315
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2361,652,432 - 61,924,912 (-)NCBI
RefSeq Acc Id: XM_039106388   ⟹   XP_038962316
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2361,652,432 - 61,924,912 (-)NCBI
RefSeq Acc Id: XM_039106389   ⟹   XP_038962317
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2361,652,432 - 61,924,912 (-)NCBI
RefSeq Acc Id: XM_039106390   ⟹   XP_038962318
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2361,652,432 - 61,924,912 (-)NCBI
RefSeq Acc Id: XM_039106391   ⟹   XP_038962319
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2361,652,432 - 61,924,912 (-)NCBI
RefSeq Acc Id: XM_039106393   ⟹   XP_038962321
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2361,652,432 - 61,924,912 (-)NCBI
RefSeq Acc Id: XM_039106394   ⟹   XP_038962322
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2361,652,432 - 61,924,912 (-)NCBI
RefSeq Acc Id: XM_039106395   ⟹   XP_038962323
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2361,652,432 - 61,924,912 (-)NCBI
RefSeq Acc Id: XM_039106396   ⟹   XP_038962324
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2361,652,432 - 61,924,912 (-)NCBI
RefSeq Acc Id: XM_039106397   ⟹   XP_038962325
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2361,652,432 - 61,924,912 (-)NCBI
RefSeq Acc Id: XM_039106398   ⟹   XP_038962326
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2361,652,432 - 61,924,912 (-)NCBI
RefSeq Acc Id: XM_039106399   ⟹   XP_038962327
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2361,652,432 - 61,924,912 (-)NCBI
RefSeq Acc Id: XM_039106400   ⟹   XP_038962328
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2361,652,432 - 61,924,912 (-)NCBI
RefSeq Acc Id: XM_039106401   ⟹   XP_038962329
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2361,652,432 - 61,924,912 (-)NCBI
RefSeq Acc Id: XM_039106402   ⟹   XP_038962330
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2361,652,432 - 61,924,912 (-)NCBI
RefSeq Acc Id: XM_039106403   ⟹   XP_038962331
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2361,652,432 - 61,924,912 (-)NCBI
RefSeq Acc Id: XM_039106404   ⟹   XP_038962332
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2361,652,432 - 61,924,912 (-)NCBI
RefSeq Acc Id: XM_039106405   ⟹   XP_038962333
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2361,652,432 - 61,924,912 (-)NCBI
RefSeq Acc Id: XM_039106406   ⟹   XP_038962334
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2361,652,432 - 61,924,912 (-)NCBI
RefSeq Acc Id: XM_039106407   ⟹   XP_038962335
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2361,652,432 - 61,924,912 (-)NCBI
RefSeq Acc Id: XM_039106408   ⟹   XP_038962336
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2361,652,432 - 61,924,912 (-)NCBI
RefSeq Acc Id: XM_039106409   ⟹   XP_038962337
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2361,652,432 - 61,924,912 (-)NCBI
RefSeq Acc Id: XM_039106410   ⟹   XP_038962338
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2361,652,432 - 61,924,912 (-)NCBI
RefSeq Acc Id: XM_039106411   ⟹   XP_038962339
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2361,652,432 - 61,924,912 (-)NCBI
RefSeq Acc Id: XM_039106412   ⟹   XP_038962340
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2361,652,432 - 61,924,912 (-)NCBI
RefSeq Acc Id: XM_039106413   ⟹   XP_038962341
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2361,652,432 - 61,924,912 (-)NCBI
RefSeq Acc Id: XM_039106414   ⟹   XP_038962342
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2361,652,432 - 61,924,912 (-)NCBI
RefSeq Acc Id: XM_039106415   ⟹   XP_038962343
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2361,652,432 - 61,924,912 (-)NCBI
RefSeq Acc Id: XM_039106416   ⟹   XP_038962344
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2361,652,432 - 61,924,912 (-)NCBI
RefSeq Acc Id: XM_039106417   ⟹   XP_038962345
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2361,652,432 - 61,924,912 (-)NCBI
RefSeq Acc Id: XM_039106418   ⟹   XP_038962346
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2361,652,432 - 61,924,912 (-)NCBI
RefSeq Acc Id: XM_039106419   ⟹   XP_038962347
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2361,652,432 - 61,924,912 (-)NCBI
RefSeq Acc Id: XM_039106420   ⟹   XP_038962348
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2361,652,432 - 61,924,912 (-)NCBI
RefSeq Acc Id: XM_039106421   ⟹   XP_038962349
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2361,652,432 - 61,924,912 (-)NCBI
RefSeq Acc Id: XM_039106422   ⟹   XP_038962350
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2361,652,432 - 61,924,912 (-)NCBI
RefSeq Acc Id: XM_039106423   ⟹   XP_038962351
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2361,652,432 - 61,924,912 (-)NCBI
RefSeq Acc Id: XM_039106424   ⟹   XP_038962352
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2361,652,432 - 61,924,912 (-)NCBI
RefSeq Acc Id: XM_039106425   ⟹   XP_038962353
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2361,652,432 - 61,924,912 (-)NCBI
RefSeq Acc Id: XM_039106426   ⟹   XP_038962354
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2361,652,432 - 61,924,912 (-)NCBI
RefSeq Acc Id: XM_039106427   ⟹   XP_038962355
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2361,652,432 - 61,924,912 (-)NCBI
RefSeq Acc Id: XM_039106428   ⟹   XP_038962356
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2361,652,432 - 61,924,912 (-)NCBI
RefSeq Acc Id: XM_039106429   ⟹   XP_038962357
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2361,652,432 - 61,924,912 (-)NCBI
RefSeq Acc Id: XM_039106430   ⟹   XP_038962358
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2361,652,432 - 61,924,912 (-)NCBI
RefSeq Acc Id: XM_039106431   ⟹   XP_038962359
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2361,652,432 - 61,924,912 (-)NCBI
RefSeq Acc Id: XM_039106432   ⟹   XP_038962360
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2361,652,432 - 61,924,912 (-)NCBI
RefSeq Acc Id: XM_039106433   ⟹   XP_038962361
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2361,652,432 - 61,924,912 (-)NCBI
RefSeq Acc Id: XM_039106434   ⟹   XP_038962362
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2361,652,432 - 61,924,912 (-)NCBI
Protein Sequences
Protein RefSeqs NP_114457 (Get FASTA)   NCBI Sequence Viewer  
  XP_038962312 (Get FASTA)   NCBI Sequence Viewer  
  XP_038962313 (Get FASTA)   NCBI Sequence Viewer  
  XP_038962314 (Get FASTA)   NCBI Sequence Viewer  
  XP_038962315 (Get FASTA)   NCBI Sequence Viewer  
  XP_038962316 (Get FASTA)   NCBI Sequence Viewer  
  XP_038962317 (Get FASTA)   NCBI Sequence Viewer  
  XP_038962318 (Get FASTA)   NCBI Sequence Viewer  
  XP_038962319 (Get FASTA)   NCBI Sequence Viewer  
  XP_038962321 (Get FASTA)   NCBI Sequence Viewer  
  XP_038962322 (Get FASTA)   NCBI Sequence Viewer  
  XP_038962323 (Get FASTA)   NCBI Sequence Viewer  
  XP_038962324 (Get FASTA)   NCBI Sequence Viewer  
  XP_038962325 (Get FASTA)   NCBI Sequence Viewer  
  XP_038962326 (Get FASTA)   NCBI Sequence Viewer  
  XP_038962327 (Get FASTA)   NCBI Sequence Viewer  
  XP_038962328 (Get FASTA)   NCBI Sequence Viewer  
  XP_038962329 (Get FASTA)   NCBI Sequence Viewer  
  XP_038962330 (Get FASTA)   NCBI Sequence Viewer  
  XP_038962331 (Get FASTA)   NCBI Sequence Viewer  
  XP_038962332 (Get FASTA)   NCBI Sequence Viewer  
  XP_038962333 (Get FASTA)   NCBI Sequence Viewer  
  XP_038962334 (Get FASTA)   NCBI Sequence Viewer  
  XP_038962335 (Get FASTA)   NCBI Sequence Viewer  
  XP_038962336 (Get FASTA)   NCBI Sequence Viewer  
  XP_038962337 (Get FASTA)   NCBI Sequence Viewer  
  XP_038962338 (Get FASTA)   NCBI Sequence Viewer  
  XP_038962339 (Get FASTA)   NCBI Sequence Viewer  
  XP_038962340 (Get FASTA)   NCBI Sequence Viewer  
  XP_038962341 (Get FASTA)   NCBI Sequence Viewer  
  XP_038962342 (Get FASTA)   NCBI Sequence Viewer  
  XP_038962343 (Get FASTA)   NCBI Sequence Viewer  
  XP_038962344 (Get FASTA)   NCBI Sequence Viewer  
  XP_038962345 (Get FASTA)   NCBI Sequence Viewer  
  XP_038962346 (Get FASTA)   NCBI Sequence Viewer  
  XP_038962347 (Get FASTA)   NCBI Sequence Viewer  
  XP_038962348 (Get FASTA)   NCBI Sequence Viewer  
  XP_038962349 (Get FASTA)   NCBI Sequence Viewer  
  XP_038962350 (Get FASTA)   NCBI Sequence Viewer  
  XP_038962351 (Get FASTA)   NCBI Sequence Viewer  
  XP_038962352 (Get FASTA)   NCBI Sequence Viewer  
  XP_038962353 (Get FASTA)   NCBI Sequence Viewer  
  XP_038962354 (Get FASTA)   NCBI Sequence Viewer  
  XP_038962355 (Get FASTA)   NCBI Sequence Viewer  
  XP_038962356 (Get FASTA)   NCBI Sequence Viewer  
  XP_038962357 (Get FASTA)   NCBI Sequence Viewer  
  XP_038962358 (Get FASTA)   NCBI Sequence Viewer  
  XP_038962359 (Get FASTA)   NCBI Sequence Viewer  
  XP_038962360 (Get FASTA)   NCBI Sequence Viewer  
  XP_038962361 (Get FASTA)   NCBI Sequence Viewer  
  XP_038962362 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA65720 (Get FASTA)   NCBI Sequence Viewer  
  AAC53425 (Get FASTA)   NCBI Sequence Viewer  
  AAC53426 (Get FASTA)   NCBI Sequence Viewer  
  AAD00527 (Get FASTA)   NCBI Sequence Viewer  
  AAF76252 (Get FASTA)   NCBI Sequence Viewer  
  AAP80789 (Get FASTA)   NCBI Sequence Viewer  
  AAP80790 (Get FASTA)   NCBI Sequence Viewer  
  AAS16364 (Get FASTA)   NCBI Sequence Viewer  
  AAS16365 (Get FASTA)   NCBI Sequence Viewer  
  AAS16366 (Get FASTA)   NCBI Sequence Viewer  
  AAS16367 (Get FASTA)   NCBI Sequence Viewer  
  AAS16368 (Get FASTA)   NCBI Sequence Viewer  
  AAS16369 (Get FASTA)   NCBI Sequence Viewer  
  AAS17013 (Get FASTA)   NCBI Sequence Viewer  
  CAB95001 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000033967.2
  ENSRNOP00000081880
  ENSRNOP00000081880.1
  ENSRNOP00000082190
  ENSRNOP00000082190.1
  ENSRNOP00000084099.1
  ENSRNOP00000086880.1
RefSeq Acc Id: XP_038962321   ⟸   XM_039106393
- Peptide Label: isoform X9
- UniProtKB: A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038962362   ⟸   XM_039106434
- Peptide Label: isoform X50
- UniProtKB: A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038962319   ⟸   XM_039106391
- Peptide Label: isoform X8
- UniProtKB: A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038962361   ⟸   XM_039106433
- Peptide Label: isoform X49
- UniProtKB: A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038962360   ⟸   XM_039106432
- Peptide Label: isoform X48
- UniProtKB: A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038962359   ⟸   XM_039106431
- Peptide Label: isoform X47
- UniProtKB: A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038962358   ⟸   XM_039106430
- Peptide Label: isoform X46
- UniProtKB: A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038962357   ⟸   XM_039106429
- Peptide Label: isoform X45
- UniProtKB: A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038962356   ⟸   XM_039106428
- Peptide Label: isoform X44
- UniProtKB: A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038962317   ⟸   XM_039106389
- Peptide Label: isoform X6
- UniProtKB: A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038962315   ⟸   XM_039106387
- Peptide Label: isoform X4
- UniProtKB: A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038962318   ⟸   XM_039106390
- Peptide Label: isoform X7
- UniProtKB: A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038962355   ⟸   XM_039106427
- Peptide Label: isoform X43
- UniProtKB: A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038962350   ⟸   XM_039106422
- Peptide Label: isoform X38
- UniProtKB: A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038962347   ⟸   XM_039106419
- Peptide Label: isoform X35
- UniProtKB: A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038962342   ⟸   XM_039106414
- Peptide Label: isoform X30
- UniProtKB: A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038962339   ⟸   XM_039106411
- Peptide Label: isoform X27
- UniProtKB: A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038962354   ⟸   XM_039106426
- Peptide Label: isoform X42
- UniProtKB: A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038962349   ⟸   XM_039106421
- Peptide Label: isoform X37
- UniProtKB: A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038962345   ⟸   XM_039106417
- Peptide Label: isoform X33
- UniProtKB: A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038962340   ⟸   XM_039106412
- Peptide Label: isoform X28
- UniProtKB: A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038962335   ⟸   XM_039106407
- Peptide Label: isoform X23
- UniProtKB: A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038962353   ⟸   XM_039106425
- Peptide Label: isoform X41
- UniProtKB: A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038962348   ⟸   XM_039106420
- Peptide Label: isoform X36
- UniProtKB: A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038962343   ⟸   XM_039106415
- Peptide Label: isoform X31
- UniProtKB: A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038962336   ⟸   XM_039106408
- Peptide Label: isoform X24
- UniProtKB: A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038962334   ⟸   XM_039106406
- Peptide Label: isoform X22
- UniProtKB: A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038962352   ⟸   XM_039106424
- Peptide Label: isoform X40
- UniProtKB: A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038962346   ⟸   XM_039106418
- Peptide Label: isoform X34
- UniProtKB: A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038962341   ⟸   XM_039106413
- Peptide Label: isoform X29
- UniProtKB: A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038962333   ⟸   XM_039106405
- Peptide Label: isoform X21
- UniProtKB: A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038962330   ⟸   XM_039106402
- Peptide Label: isoform X18
- UniProtKB: A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038962351   ⟸   XM_039106423
- Peptide Label: isoform X39
- UniProtKB: A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038962344   ⟸   XM_039106416
- Peptide Label: isoform X32
- UniProtKB: A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038962337   ⟸   XM_039106409
- Peptide Label: isoform X25
- UniProtKB: A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038962331   ⟸   XM_039106403
- Peptide Label: isoform X19
- UniProtKB: A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038962328   ⟸   XM_039106400
- Peptide Label: isoform X16
- UniProtKB: A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038962338   ⟸   XM_039106410
- Peptide Label: isoform X26
- UniProtKB: A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038962332   ⟸   XM_039106404
- Peptide Label: isoform X20
- UniProtKB: A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038962326   ⟸   XM_039106398
- Peptide Label: isoform X14
- UniProtKB: A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038962324   ⟸   XM_039106396
- Peptide Label: isoform X12
- UniProtKB: A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038962329   ⟸   XM_039106401
- Peptide Label: isoform X17
- UniProtKB: A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038962327   ⟸   XM_039106399
- Peptide Label: isoform X15
- UniProtKB: A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038962325   ⟸   XM_039106397
- Peptide Label: isoform X13
- UniProtKB: A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038962323   ⟸   XM_039106395
- Peptide Label: isoform X11
- UniProtKB: A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038962322   ⟸   XM_039106394
- Peptide Label: isoform X10
- UniProtKB: A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038962314   ⟸   XM_039106386
- Peptide Label: isoform X3
- UniProtKB: A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038962316   ⟸   XM_039106388
- Peptide Label: isoform X5
- UniProtKB: A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038962312   ⟸   XM_039106384
- Peptide Label: isoform X1
- UniProtKB: A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038962313   ⟸   XM_039106385
- Peptide Label: isoform X2
- UniProtKB: A0A8I5ZUN3 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSRNOP00000084099   ⟸   ENSRNOT00000107188
RefSeq Acc Id: ENSRNOP00000082190   ⟸   ENSRNOT00000114553
RefSeq Acc Id: ENSRNOP00000086880   ⟸   ENSRNOT00000108121
RefSeq Acc Id: ENSRNOP00000033967   ⟸   ENSRNOT00000030978
RefSeq Acc Id: ENSRNOP00000081880   ⟸   ENSRNOT00000101577
Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:621114 AgrOrtholog
BioCyc Gene G2FUF-49275 BioCyc
Ensembl Genes ENSRNOG00000069271 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000030978.3 UniProtKB/TrEMBL
  ENSRNOT00000101577 ENTREZGENE
  ENSRNOT00000101577.1 UniProtKB/TrEMBL
  ENSRNOT00000107188.1 UniProtKB/TrEMBL
  ENSRNOT00000108121.1 UniProtKB/TrEMBL
  ENSRNOT00000114553 ENTREZGENE
  ENSRNOT00000114553.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/TrEMBL
  Transferase(Phosphotransferase) domain 1 UniProtKB/TrEMBL
InterPro Basigin-like UniProtKB/TrEMBL
  FN3_dom UniProtKB/TrEMBL
  FN3_sf UniProtKB/TrEMBL
  Ig-like_dom UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Ig_I-set UniProtKB/TrEMBL
  Ig_sub UniProtKB/TrEMBL
  Ig_sub2 UniProtKB/TrEMBL
  Ig_V-set UniProtKB/TrEMBL
  Kinase-like_dom_sf UniProtKB/TrEMBL
  MyBP-C_THB UniProtKB/TrEMBL
  PPAK_motif UniProtKB/TrEMBL
  Prot_kinase_dom UniProtKB/TrEMBL
  Titin_Z_rpt UniProtKB/TrEMBL
  Tyr_kinase_AS UniProtKB/TrEMBL
NCBI Gene 84015 ENTREZGENE
PANTHER BASIGIN RELATED UniProtKB/TrEMBL
  IMMUNOGLOBULIN UniProtKB/TrEMBL
  KETN-1 UniProtKB/TrEMBL
  LP07818P1 UniProtKB/TrEMBL
  OUTER MEMBRANE CHANNEL PROTEIN CPNT UniProtKB/TrEMBL
  PTHR10075:SF97 UniProtKB/TrEMBL
  PTHR14340 UniProtKB/TrEMBL
  TITIN UniProtKB/TrEMBL
  TITIN UniProtKB/TrEMBL
  ZORMIN, ISOFORM J UniProtKB/TrEMBL
Pfam fn3; 132 UniProtKB/TrEMBL
  I-set UniProtKB/TrEMBL
  Pkinase UniProtKB/TrEMBL
  PPAK UniProtKB/TrEMBL
  THB UniProtKB/TrEMBL
  Titin_Z UniProtKB/TrEMBL
PhenoGen Ttn PhenoGen
PRINTS FNTYPEIII UniProtKB/TrEMBL
  PRICHEXTENSN UniProtKB/TrEMBL
PROSITE FN3; 132 UniProtKB/TrEMBL
  IG_LIKE UniProtKB/TrEMBL
  PROTEIN_KINASE_DOM UniProtKB/TrEMBL
  PROTEIN_KINASE_TYR UniProtKB/TrEMBL
RatGTEx ENSRNOG00000069271 RatGTEx
SMART FN3; 132 UniProtKB/TrEMBL
  IGc2 UniProtKB/TrEMBL
  IGv UniProtKB/TrEMBL
  SM00409 UniProtKB/TrEMBL
Superfamily-SCOP SSF48726 UniProtKB/TrEMBL
  SSF49265 UniProtKB/TrEMBL
  SSF56112 UniProtKB/TrEMBL
UniProt A0A8I5ZU83_RAT UniProtKB/TrEMBL
  A0A8I5ZUN3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZX32_RAT UniProtKB/TrEMBL
  A0A8I6A794_RAT UniProtKB/TrEMBL
  D4A8Y1_RAT UniProtKB/TrEMBL
  Q5VJM3_RAT UniProtKB/TrEMBL
  Q5VJM4_RAT UniProtKB/TrEMBL
  Q5VJM5_RAT UniProtKB/TrEMBL
  Q5VJM6_RAT UniProtKB/TrEMBL
  Q5VJM7_RAT UniProtKB/TrEMBL
  Q9JHQ1_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-06-02 Ttn  titin  Ttn  titin  Data merged from RGD:149736286 737654 PROVISIONAL
2021-08-09 Ttn  titin      Symbol and Name status set to provisional 45752 PROVISIONAL
2004-09-10 Ttn  titin      Symbol and Name status set to approved 1299863 APPROVED
2002-08-07 Ttn  titin      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_function acts as a template for myosin incorporation into thick filaments 634444