Dnaja1 (DnaJ heat shock protein family (Hsp40) member A1) - Rat Genome Database

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Gene: Dnaja1 (DnaJ heat shock protein family (Hsp40) member A1) Rattus norvegicus
Analyze
Symbol: Dnaja1
Name: DnaJ heat shock protein family (Hsp40) member A1
RGD ID: 620942
Description: Enables ATPase activator activity. Predicted to be involved in several processes, including negative regulation of protein modification process; regulation of apoptotic process; and regulation of establishment of protein localization. Predicted to act upstream of or within androgen receptor signaling pathway; flagellated sperm motility; and spermatogenesis. Predicted to be located in membrane. Predicted to be active in cytosol. Orthologous to human DNAJA1 (DnaJ heat shock protein family (Hsp40) member A1); PARTICIPATES IN Endoplasmic Reticulum-associated degradation pathway; INTERACTS WITH 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: DnaJ (Hsp40) homolog, subfamily A, member 1; dnaJ homolog subfamily A member 1; DnaJ-like protein; dnaJ-like protein 1; DnaJ-like protein 2; heat shock protein J2; HSJ-2; Hsj2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8560,638,404 - 60,649,315 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl560,638,410 - 60,650,160 (+)EnsemblGRCr8
mRatBN7.2555,842,414 - 55,853,326 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl555,842,426 - 55,853,967 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx557,808,082 - 57,819,013 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0559,627,243 - 59,638,175 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0559,621,333 - 59,632,246 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0557,028,467 - 57,039,378 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl557,028,467 - 57,039,378 (+)Ensemblrn6Rnor6.0
Rnor_5.0561,562,288 - 61,573,851 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4558,100,794 - 58,111,705 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera554,454,606 - 54,465,517 (+)NCBICelera
RGSC_v3.1558,100,972 - 58,111,884 (+)NCBI
Cytogenetic Map5q22NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
(S)-nicotine  (ISO)
1,1-dichloroethene  (ISO)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine  (ISO)
1-naphthyl isothiocyanate  (EXP)
17beta-estradiol  (ISO)
1H-pyrazole  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-tribromophenol  (ISO)
2,6-dimethoxyphenol  (ISO)
2,6-dinitrotoluene  (EXP)
2-butoxyethanol  (ISO)
2-methylcholine  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
3H-1,2-dithiole-3-thione  (EXP)
4,4'-sulfonyldiphenol  (ISO)
9-cis-retinoic acid  (EXP)
acetamide  (EXP)
aconitine  (EXP)
acrylamide  (ISO)
actinomycin D  (ISO)
afimoxifene  (ISO)
aflatoxin B1  (ISO)
ammonium chloride  (EXP)
amphetamine  (EXP)
amphibole asbestos  (ISO)
arecoline  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenous acid  (ISO)
Aurin  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[b]fluoranthene  (ISO)
benzo[e]pyrene  (ISO)
Benzo[ghi]perylene  (ISO)
Benzo[k]fluoranthene  (ISO)
beta-naphthoflavone  (ISO)
bexarotene  (EXP)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol AF  (ISO)
bisphenol F  (ISO)
Butylbenzyl phthalate  (EXP,ISO)
cadmium acetate  (EXP)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
caffeine  (ISO)
carbamazepine  (ISO)
carbon nanotube  (ISO)
carbonyl cyanide p-trifluoromethoxyphenylhydrazone  (ISO)
celastrol  (ISO)
chloropicrin  (ISO)
chrysene  (ISO)
cisplatin  (ISO)
clofibrate  (EXP,ISO)
clofibric acid  (EXP)
cobalt dichloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
crocidolite asbestos  (ISO)
CU-O LINKAGE  (ISO)
cyclosporin A  (ISO)
deoxynivalenol  (ISO)
dexamethasone  (ISO)
diarsenic trioxide  (ISO)
dibenz[a,h]anthracene  (ISO)
dibutyl phthalate  (EXP)
diclofenac  (ISO)
dicrotophos  (ISO)
dioxygen  (ISO)
disulfiram  (ISO)
diuron  (EXP)
doxorubicin  (EXP,ISO)
enzyme inhibitor  (ISO)
ethanol  (ISO)
flutamide  (EXP)
FR900359  (ISO)
fulvestrant  (ISO)
furan  (ISO)
furfural  (ISO)
gallium nitrate  (ISO)
gedunin  (ISO)
gentamycin  (EXP)
glutathione  (ISO)
hyaluronic acid  (EXP)
hydrogen peroxide  (EXP,ISO)
hydroquinone  (ISO)
Indeno[1,2,3-cd]pyrene  (ISO)
indometacin  (ISO)
isobutanol  (ISO)
isoniazide  (ISO)
ivermectin  (ISO)
kojic acid  (EXP)
lead diacetate  (ISO)
leflunomide  (ISO)
lipopolysaccharide  (ISO)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
methamphetamine  (EXP)
methapyrilene  (ISO)
methotrexate  (ISO)
methylparaben  (ISO)
monocrotaline  (ISO)
monosodium L-glutamate  (ISO)
N-methylformamide  (ISO)
N-nitrosodiethylamine  (EXP)
nefazodone  (EXP)
niclosamide  (ISO)
nicotine  (ISO)
nitrates  (ISO)
Nutlin-3  (ISO)
okadaic acid  (ISO)
organoselenium compound  (ISO)
ozone  (ISO)
paracetamol  (EXP,ISO)
pentachlorophenol  (ISO)
perfluorohexanesulfonic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (EXP)
phenobarbital  (EXP,ISO)
phenytoin  (ISO)
pirinixic acid  (ISO)
piroxicam  (ISO)
potassium dichromate  (ISO)
pravastatin  (ISO)
procymidone  (EXP)
propiconazole  (ISO)
quercetin  (ISO)
raloxifene  (ISO)
resveratrol  (ISO)
rifampicin  (ISO)
rotenone  (EXP)
sarin  (ISO)
SCH 23390  (EXP)
silicon dioxide  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
silver(1+) nitrate  (ISO)
sodium arsenite  (ISO)
sodium chloride  (ISO)
succimer  (ISO)
tetrachloromethane  (ISO)
tetraphene  (ISO)
thapsigargin  (ISO)
thiostrepton  (ISO)
thiram  (ISO)
titanium dioxide  (EXP,ISO)
trichloroethene  (EXP,ISO)
triphenyl phosphate  (ISO)
triptonide  (ISO)
troglitazone  (ISO)
tunicamycin  (ISO)
urethane  (ISO)
valproic acid  (EXP,ISO)
vinclozolin  (EXP)
zinc atom  (ISO)
zinc pyrithione  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Induction of molecular chaperones in carbon tetrachloride-treated rat liver: implications in protection against liver damage. Lee KJ, etal., Cell Stress Chaperones. 2004 Mar;9(1):58-68.
4. Isolation and characterization of a DnaJ-like protein in rats: the C-terminal 10-kDa domain of hsc70 is not essential for stimulating the ATP-hydrolytic activity of hsc70 by a DnaJ-like protein. Leng CH, etal., Protein Sci 1998 May;7(5):1186-94.
5. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
6. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
7. Pituitary tumor-transforming gene protein associates with ribosomal protein S10 and a novel human homologue of DnaJ in testicular cells. Pei L J Biol Chem. 1999 Jan 29;274(5):3151-8.
8. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
9. GOA pipeline RGD automated data pipeline
10. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
11. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:12150907   PMID:14752510   PMID:15082773   PMID:15489334   PMID:15660130   PMID:16854843   PMID:17110338   PMID:19056867   PMID:19946888   PMID:20458337   PMID:21231916   PMID:23716698  
PMID:24318877   PMID:24512202   PMID:24625528   PMID:25002582   PMID:25281747   PMID:26959111   PMID:30053369  


Genomics

Comparative Map Data
Dnaja1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8560,638,404 - 60,649,315 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl560,638,410 - 60,650,160 (+)EnsemblGRCr8
mRatBN7.2555,842,414 - 55,853,326 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl555,842,426 - 55,853,967 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx557,808,082 - 57,819,013 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0559,627,243 - 59,638,175 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0559,621,333 - 59,632,246 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0557,028,467 - 57,039,378 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl557,028,467 - 57,039,378 (+)Ensemblrn6Rnor6.0
Rnor_5.0561,562,288 - 61,573,851 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4558,100,794 - 58,111,705 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera554,454,606 - 54,465,517 (+)NCBICelera
RGSC_v3.1558,100,972 - 58,111,884 (+)NCBI
Cytogenetic Map5q22NCBI
DNAJA1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38933,025,273 - 33,039,907 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl933,025,206 - 33,039,916 (+)Ensemblhg38GRCh38
GRCh37933,025,271 - 33,039,905 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36933,015,209 - 33,029,062 (+)NCBIBuild 36Build 36hg18NCBI36
Build 34933,015,208 - 33,029,062NCBI
Celera932,956,506 - 32,970,354 (+)NCBICelera
Cytogenetic Map9p21.1NCBI
HuRef932,983,591 - 32,997,444 (+)NCBIHuRef
CHM1_1933,024,975 - 33,038,828 (+)NCBICHM1_1
T2T-CHM13v2.0933,041,834 - 33,056,468 (+)NCBIT2T-CHM13v2.0
Dnaja1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39440,722,468 - 40,734,965 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl440,722,150 - 40,737,149 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38440,722,468 - 40,734,965 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl440,722,150 - 40,737,149 (+)Ensemblmm10GRCm38
MGSCv37440,669,501 - 40,684,186 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36440,911,204 - 40,923,635 (+)NCBIMGSCv36mm8
Celera440,382,728 - 40,397,413 (+)NCBICelera
Cytogenetic Map4A5NCBI
cM Map420.46NCBI
Dnaja1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554722,604,002 - 2,618,033 (-)Ensembl
ChiLan1.0NW_0049554722,604,002 - 2,618,033 (-)NCBIChiLan1.0ChiLan1.0
DNAJA1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21191,567,747 - 91,582,267 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1991,573,939 - 91,588,209 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0932,800,077 - 32,814,745 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1933,608,502 - 33,622,275 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl933,608,502 - 33,622,275 (+)EnsemblpanPan2panpan1.1
DNAJA1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11150,156,089 - 50,168,379 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1150,156,089 - 50,167,536 (+)EnsemblcanFam3CanFam3.1
ROS_Cfam_1.01721,302,373 - 21,303,842 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
UMICH_Zoey_3.1768,911,054 - 68,912,003 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02025,645,023 - 25,646,492 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02629,882,770 - 29,884,243 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Dnaja1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947165,052,278 - 165,063,722 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365241,599,913 - 1,610,682 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365241,599,883 - 1,611,302 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DNAJA1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1033,432,844 - 33,445,532 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11033,432,529 - 33,445,556 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21037,687,721 - 37,699,598 (-)NCBISscrofa10.2Sscrofa10.2susScr3
DNAJA1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11247,220,976 - 47,235,684 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366603844,122,907 - 44,137,626 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Dnaja1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473637,780,867 - 37,793,594 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462473637,780,852 - 37,793,594 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Dnaja1
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11117,501,746 - 117,511,282 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Dnaja1
51 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:181
Count of miRNA genes:115
Interacting mature miRNAs:131
Transcripts:ENSRNOT00000010061
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1578776Stresp18Stress response QTL 182.9thymus mass (VT:0004954)thymus wet weight (CMO:0000855)53275164977751649Rat
1298067Scl15Serum cholesterol level QTL 154.80.001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)53801167083011670Rat
1300115Hrtrt7Heart rate QTL 72.76heart pumping trait (VT:2000009)heart rate (CMO:0000002)55266537294894052Rat
6907115Mcs29Mammary carcinoma susceptibility QTL 29mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)53800433183004331Rat
1549845Scl44Serum cholesterol level QTL 446blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)544924861153890773Rat
1358353Srcrtb2Stress Responsive Cort Basal QTL 23.480.003blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)52367149379046465Rat
70212Niddm25Non-insulin dependent diabetes mellitus QTL 253.54blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)538207390136631402Rat
634305Mamtr1Mammary tumor resistance QTL 10.0001mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)51757663362576633Rat
1331801Rf33Renal function QTL 334.149kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)548523123134369373Rat
1578774Tcas8Tongue tumor susceptibility QTL 83.47tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)51570745160707451Rat
1598807Glom12Glomerulus QTL 122.7kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)53801167083011670Rat
1302786Kidm8Kidney mass QTL 828.15kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)53801167083011670Rat
1331782Rf36Renal function QTL 363.296kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)539019942102105896Rat
6903292Stl28Serum triglyceride level QTL 282.60.0073blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)53331167378311673Rat
1578766Tcas11Tongue tumor susceptibility QTL 114.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)551657967166600247Rat
1578767Stresp17Stress response QTL 174.30.01blood aldosterone amount (VT:0005346)plasma aldosterone level (CMO:0000551)53275164977751649Rat
1641922Alcrsp8Alcohol response QTL 8alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)51748608062486080Rat
1576312Emca8Estrogen-induced mammary cancer QTL 84.1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)555124766172190305Rat
1641912Alcrsp18Alcohol response QTL 18response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)53998594884985948Rat
1576314Eutr1Estrogen induced uterine response QTL 1uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)5692228281330203Rat
6903306Scl35Serum cholesterol QTL 352.60.0073blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)53331167378311673Rat
1576317Eutr2Estrogen induced uterine response QTL 20.01uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)53952692484526924Rat
1331773Scl26Serum cholesterol level QTL 263.065blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)54852312391770353Rat
70189Mcs5Mammary carcinoma susceptibility QTL 510.51mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)560601597137492949Rat
1331771Rf35Renal function QTL 354.36965kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)51001906491770353Rat
61359EaexExperimental allergic encephalomyelitis QTL x3nervous system integrity trait (VT:0010566)post-insult time to onset of experimental autoimmune encephalomyelitis (CMO:0001422)560511627105511627Rat
8662454Vetf3Vascular elastic tissue fragility QTL 327.4artery integrity trait (VT:0010639)number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)5706553574335773Rat
2290448Scl54Serum cholesterol level QTL 542.93blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)536460764136631402Rat
1641903Alcrsp3Alcohol response QTL 3response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)51748608062486080Rat
1331756Rf34Renal function QTL 344.16275kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)51001906487027358Rat
8552954Pigfal14Plasma insulin-like growth factor 1 level QTL 149blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)52602321171023211Rat
2303577Gluco47Glucose level QTL 473blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)51652001961520019Rat
2316959Gluco59Glucose level QTL 594.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)556546393101546393Rat
1600358Mamtr5Mammary tumor resistance QTL 5mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)52367149368671493Rat

Markers in Region
PMC153017P1  
Rat AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map5q22UniSTS
RH135166  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2555,852,909 - 55,853,117 (+)MAPPERmRatBN7.2
Rnor_6.0557,038,962 - 57,039,169NCBIRnor6.0
Rnor_5.0561,572,783 - 61,572,990UniSTSRnor5.0
RGSC_v3.4558,111,289 - 58,111,496UniSTSRGSC3.4
Celera554,465,101 - 54,465,308UniSTS
RH 3.4 Map5288.3UniSTS
Cytogenetic Map5q22UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000010061   ⟹   ENSRNOP00000010061
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl560,638,410 - 60,649,959 (+)Ensembl
mRatBN7.2 Ensembl555,842,426 - 55,853,967 (+)Ensembl
Rnor_6.0 Ensembl557,028,467 - 57,039,378 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000095533   ⟹   ENSRNOP00000079023
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl560,639,782 - 60,650,160 (+)Ensembl
mRatBN7.2 Ensembl555,842,809 - 55,853,967 (+)Ensembl
RefSeq Acc Id: NM_022934   ⟹   NP_075223
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8560,638,404 - 60,649,315 (+)NCBI
mRatBN7.2555,842,414 - 55,853,326 (+)NCBI
Rnor_6.0557,028,467 - 57,039,378 (+)NCBI
Rnor_5.0561,562,288 - 61,573,851 (+)NCBI
RGSC_v3.4558,100,794 - 58,111,705 (+)RGD
Celera554,454,606 - 54,465,517 (+)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_075223 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA98855 (Get FASTA)   NCBI Sequence Viewer  
  AAH62009 (Get FASTA)   NCBI Sequence Viewer  
  EDL98641 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000010061
  ENSRNOP00000010061.2
GenBank Protein P63036 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_075223   ⟸   NM_022934
- UniProtKB: P63036 (UniProtKB/Swiss-Prot),   A6IIS1 (UniProtKB/TrEMBL),   A0A8I5ZPY5 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000010061   ⟸   ENSRNOT00000010061
Ensembl Acc Id: ENSRNOP00000079023   ⟸   ENSRNOT00000095533
Protein Domains
CR-type   J

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P63036-F1-model_v2 AlphaFold P63036 1-397 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13693635
Promoter ID:EPDNEW_R4159
Type:multiple initiation site
Name:Dnaja1_1
Description:DnaJ heat shock protein family member A1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0557,028,475 - 57,028,535EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:620942 AgrOrtholog
BioCyc Gene G2FUF-41590 BioCyc
Ensembl Genes ENSRNOG00000007029 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000010061 ENTREZGENE
  ENSRNOT00000010061.4 UniProtKB/Swiss-Prot
Gene3D-CATH 1.10.287.110 UniProtKB/Swiss-Prot
  Heat shock protein DnaJ, cysteine-rich domain UniProtKB/Swiss-Prot
  Urease metallochaperone UreE, N-terminal domain UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:5621557 IMAGE-MGC_LOAD
InterPro DnaJ UniProtKB/Swiss-Prot
  DnaJ_C UniProtKB/Swiss-Prot
  DnaJ_domain UniProtKB/Swiss-Prot
  DnaJ_domain_CS UniProtKB/Swiss-Prot
  DNJA1/2-like UniProtKB/Swiss-Prot
  HSP40/DnaJ_pept-bd UniProtKB/Swiss-Prot
  HSP_DnaJ_Cys-rich_dom UniProtKB/Swiss-Prot
  HSP_DnaJ_Cys-rich_dom_sf UniProtKB/Swiss-Prot
  J_dom_sf UniProtKB/Swiss-Prot
KEGG Report rno:65028 UniProtKB/Swiss-Prot
MGC_CLONE MGC:72435 IMAGE-MGC_LOAD
NCBI Gene 65028 ENTREZGENE
PANTHER PTHR43888 UniProtKB/Swiss-Prot
Pfam DnaJ UniProtKB/Swiss-Prot
  DnaJ_C UniProtKB/Swiss-Prot
  DnaJ_CXXCXGXG UniProtKB/Swiss-Prot
PhenoGen Dnaja1 PhenoGen
PRINTS JDOMAIN UniProtKB/Swiss-Prot
PROSITE DNAJ_1 UniProtKB/Swiss-Prot
  DNAJ_2 UniProtKB/Swiss-Prot
  ZF_CR UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000007029 RatGTEx
SMART DnaJ UniProtKB/Swiss-Prot
Superfamily-SCOP SSF46565 UniProtKB/Swiss-Prot
  SSF49493 UniProtKB/Swiss-Prot
  SSF57938 UniProtKB/Swiss-Prot
UniProt A0A8I5ZPY5 ENTREZGENE, UniProtKB/TrEMBL
  A6IIS1 ENTREZGENE, UniProtKB/TrEMBL
  DNJA1_RAT UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary P54102 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-11-25 Dnaja1  DnaJ heat shock protein family (Hsp40) member A1  Dnaja1  DnaJ (Hsp40) homolog, subfamily A, member 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Dnaja1  DnaJ (Hsp40) homolog, subfamily A, member 1    DnaJ-like protein  Name updated 1299863 APPROVED
2004-09-10 Dnaja1  DnaJ-like protein  Hsj2    Symbol and Name updated 1299863 APPROVED
2002-08-07 Hsj2  DnaJ-like protein      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_homology 99% identity to human HDJ2 633115
gene_protein 397 amino acid residues 633115