Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Acmsd | Rat | (+)-schisandrin B | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of ACMSD mRNA] | CTD | PMID:31150632 | Acmsd | Rat | 1-nitropropane | increases expression | EXP | | 6480464 | 1-nitropropane results in increased expression of ACMSD mRNA | CTD | PMID:17070881 | Acmsd | Rat | 17beta-estradiol | decreases expression | ISO | ACMSD (Homo sapiens) | 6480464 | Estradiol results in decreased expression of ACMSD mRNA | CTD | PMID:20106945 | Acmsd | Rat | 17beta-estradiol | decreases expression | EXP | | 6480464 | Estradiol results in decreased expression of ACMSD mRNA | CTD | PMID:32145629 | Acmsd | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Acmsd (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of ACMSD mRNA | CTD | PMID:21889950 | Acmsd | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of ACMSD mRNA | CTD | PMID:21215274 | Acmsd | Rat | 2,4-diaminotoluene | decreases expression | EXP | | 6480464 | 2 and 4-diaminotoluene results in decreased expression of ACMSD mRNA | CTD | PMID:17070881 | Acmsd | Rat | 2,6-diaminotoluene | increases expression | EXP | | 6480464 | 2 and 6-diaminotoluene results in increased expression of ACMSD mRNA | CTD | PMID:17070881 | Acmsd | Rat | 2-acetamidofluorene | decreases expression | EXP | | 6480464 | 2-Acetylaminofluorene results in decreased expression of ACMSD mRNA | CTD | PMID:17070881 | Acmsd | Rat | 2-nitro-p-phenylenediamine | decreases expression | EXP | | 6480464 | 2-nitro-4-phenylenediamine results in decreased expression of ACMSD mRNA | CTD | PMID:17070881 | Acmsd | Rat | 2-nitropropane | decreases expression | EXP | | 6480464 | 2-nitropropane results in decreased expression of ACMSD mRNA | CTD | PMID:17070881 | Acmsd | Rat | 3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine | decreases activity | EXP | | 6480464 | Puromycin Aminonucleoside results in decreased activity of ACMSD protein | CTD | PMID:16711654 | Acmsd | Rat | 3-[3-(tert-butylsulfanyl)-1-(4-chlorobenzyl)-5-(propan-2-yl)-1H-indol-2-yl]-2,2-dimethylpropanoic acid | multiple interactions | EXP | | 6480464 | MK-886 inhibits the reaction [pirinixic acid results in decreased expression of ACMSD mRNA] | CTD | PMID:18320257 | Acmsd | Rat | 3-chloropropane-1,2-diol | decreases expression | EXP | | 6480464 | alpha-Chlorohydrin results in decreased expression of ACMSD protein | CTD | PMID:34915118 | Acmsd | Rat | 4,4'-sulfonyldiphenol | decreases expression | ISO | Acmsd (Mus musculus) | 6480464 | bisphenol S results in decreased expression of ACMSD mRNA | CTD | PMID:33297965 | Acmsd | Rat | 4-acetylaminofluorene | increases expression | EXP | | 6480464 | 4-acetylaminofluorene results in increased expression of ACMSD mRNA | CTD | PMID:17070881 | Acmsd | Rat | 4-nitro-1,2-phenylenediamine | decreases expression | EXP | | 6480464 | 1 and 2-diamino-4-nitrobenzene results in decreased expression of ACMSD mRNA | CTD | PMID:17070881 | Acmsd | Rat | acetamide | increases expression | EXP | | 6480464 | acetamide results in increased expression of ACMSD mRNA | CTD | PMID:31881176 | Acmsd | Rat | acrylamide | decreases expression | EXP | | 6480464 | Acrylamide results in decreased expression of ACMSD mRNA | CTD | PMID:28959563 | Acmsd | Rat | adenine | decreases activity | EXP | | 6480464 | Adenine results in decreased activity of ACMSD protein | CTD | PMID:11758903 | Acmsd | Rat | aflatoxin B1 | affects expression | ISO | ACMSD (Homo sapiens) | 6480464 | Aflatoxin B1 affects the expression of ACMSD protein | CTD | PMID:20106945 | Acmsd | Rat | aflatoxin B1 | decreases methylation | ISO | ACMSD (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of ACMSD gene | CTD | PMID:27153756 | Acmsd | Rat | aflatoxin B1 | decreases expression | ISO | ACMSD (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased expression of ACMSD mRNA | CTD | PMID:22100608 and PMID:27153756 | Acmsd | Rat | ammonium chloride | affects expression | EXP | | 6480464 | Ammonium Chloride affects the expression of ACMSD mRNA | CTD | PMID:16483693 | Acmsd | Rat | arsane | decreases expression | ISO | Acmsd (Mus musculus) | 6480464 | Arsenic results in decreased expression of ACMSD mRNA | CTD | PMID:36463740 | Acmsd | Rat | arsenic atom | decreases expression | ISO | Acmsd (Mus musculus) | 6480464 | Arsenic results in decreased expression of ACMSD mRNA | CTD | PMID:36463740 | Acmsd | Rat | benzo[a]pyrene | increases methylation | ISO | ACMSD (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of ACMSD promoter | CTD | PMID:27901495 | Acmsd | Rat | benzo[a]pyrene | decreases expression | ISO | ACMSD (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased expression of ACMSD mRNA | CTD | PMID:32234424 | Acmsd | Rat | bis(2-ethylhexyl) phthalate | decreases expression | ISO | Acmsd (Mus musculus) | 6480464 | Diethylhexyl Phthalate results in decreased expression of ACMSD mRNA | CTD | PMID:19850644 | Acmsd | Rat | bis(2-ethylhexyl) phthalate | multiple interactions | EXP | | 6480464 | [Diethylhexyl Phthalate results in decreased activity of ACMSD protein] which results in increased abundance of Niacin | CTD | PMID:12036039 | Acmsd | Rat | bis(2-ethylhexyl) phthalate | decreases activity | EXP | | 6480464 | Diethylhexyl Phthalate results in decreased activity of ACMSD protein | CTD | PMID:12036039 | Acmsd | Rat | bis(2-ethylhexyl) phthalate | multiple interactions | ISO | Acmsd (Mus musculus) | 6480464 | PPARA protein promotes the reaction [Diethylhexyl Phthalate results in decreased expression of ACMSD mRNA] | CTD | PMID:19850644 | Acmsd | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of ACMSD mRNA | CTD | PMID:25181051 and PMID:32145629 | Acmsd | Rat | bisphenol A | increases expression | ISO | Acmsd (Mus musculus) | 6480464 | bisphenol A results in increased expression of ACMSD mRNA | CTD | PMID:33221593 | Acmsd | Rat | bisphenol A | increases methylation | ISO | Acmsd (Mus musculus) | 6480464 | bisphenol A results in increased methylation of ACMSD promoter | CTD | PMID:27312807 | Acmsd | Rat | carbon nanotube | decreases expression | ISO | Acmsd (Mus musculus) | 6480464 | Nanotubes more ... | CTD | PMID:25620056 | Acmsd | Rat | cefaloridine | decreases expression | EXP | | 6480464 | Cephaloridine results in decreased expression of ACMSD mRNA | CTD | PMID:18500788 | Acmsd | Rat | chlorpyrifos | increases expression | EXP | | 6480464 | Chlorpyrifos results in increased expression of ACMSD mRNA | CTD | PMID:21968025 | Acmsd | Rat | clofibric acid | affects expression | EXP | | 6480464 | Clofibric Acid affects the expression of ACMSD mRNA | CTD | PMID:17602206 | Acmsd | Rat | clofibric acid | multiple interactions | EXP | | 6480464 | [Clofibric Acid co-treated with Diethylnitrosamine] results in decreased expression of ACMSD mRNA | CTD | PMID:15833021 | Acmsd | Rat | clofibric acid | decreases expression | EXP | | 6480464 | Clofibric Acid results in decreased expression of ACMSD mRNA | CTD | PMID:15833021 | Acmsd | Rat | cyclosporin A | decreases expression | ISO | ACMSD (Homo sapiens) | 6480464 | Cyclosporine results in decreased expression of ACMSD mRNA | CTD | PMID:20106945 and PMID:27989131 | Acmsd | Rat | diazinon | increases expression | EXP | | 6480464 | Diazinon results in increased expression of ACMSD mRNA | CTD | PMID:21968025 | Acmsd | Rat | dibutyl phthalate | multiple interactions | EXP | | 6480464 | Dibutyl Phthalate affects the reaction [ACMSD protein affects the abundance of Niacin] | CTD | PMID:12036039 | Acmsd | Rat | furan | increases expression | ISO | Acmsd (Mus musculus) | 6480464 | furan results in increased expression of ACMSD mRNA | CTD | PMID:24183702 | Acmsd | Rat | furan | increases expression | EXP | | 6480464 | furan results in increased expression of ACMSD mRNA | CTD | PMID:26194646 | Acmsd | Rat | gentamycin | decreases expression | EXP | | 6480464 | Gentamicins results in decreased expression of ACMSD protein | CTD | PMID:21081137 and PMID:22061828 | Acmsd | Rat | hydroquinone O-beta-D-glucopyranoside | decreases expression | ISO | ACMSD (Homo sapiens) | 6480464 | Arbutin results in decreased expression of ACMSD mRNA | CTD | PMID:17103032 | Acmsd | Rat | kojic acid | decreases expression | ISO | ACMSD (Homo sapiens) | 6480464 | kojic acid results in decreased expression of ACMSD mRNA | CTD | PMID:16595896 | Acmsd | Rat | linoleic acid | decreases expression | EXP | | 6480464 | Linoleic Acid results in decreased expression of ACMSD mRNA | CTD | PMID:18320257 | Acmsd | Rat | metformin | decreases expression | EXP | | 6480464 | Metformin results in decreased expression of ACMSD mRNA | CTD | PMID:31324951 | Acmsd | Rat | N-methyl-6-pyridone-3-carboxamide | multiple interactions | ISO | Acmsd (Mus musculus) | 6480464 | [ACMSD protein affects the metabolism of Niacin] which affects the abundance of N'-methyl-2-pyridone-5-carboxamide | CTD | PMID:38374343 | Acmsd | Rat | N-methyl-6-pyridone-3-carboxamide | affects abundance | ISO | Acmsd (Mus musculus) | 6480464 | ACMSD protein affects the abundance of N'-methyl-2-pyridone-5-carboxamide | CTD | PMID:38374343 | Acmsd | Rat | N-nitrosodiethylamine | multiple interactions | EXP | | 6480464 | [Clofibric Acid co-treated with Diethylnitrosamine] results in decreased expression of ACMSD mRNA | CTD | PMID:15833021 | Acmsd | Rat | NAD zwitterion | increases abundance | EXP | | 6480464 | ACMSD protein results in increased abundance of NAD | CTD | PMID:17896587 | Acmsd | Rat | NAD(+) | increases abundance | EXP | | 6480464 | ACMSD protein results in increased abundance of NAD | CTD | PMID:17896587 | Acmsd | Rat | nicotinic acid | affects abundance | EXP | | 6480464 | ACMSD protein affects the abundance of Niacin | CTD | PMID:12036039 | Acmsd | Rat | nicotinic acid | affects metabolic processing | ISO | Acmsd (Mus musculus) | 6480464 | ACMSD protein affects the metabolism of Niacin | CTD | PMID:38374343 | Acmsd | Rat | nicotinic acid | multiple interactions | ISO | Acmsd (Mus musculus) | 6480464 | [ACMSD protein affects the metabolism of Niacin] which affects the abundance of N'-methyl-2-pyridone-5-carboxamide and [ACMSD protein affects the metabolism of Niacin] which affects the abundance of N(1)-methyl-4-pyridone-5-carboxamide | CTD | PMID:38374343 | Acmsd | Rat | nicotinic acid | multiple interactions | EXP | | 6480464 | [Diethylhexyl Phthalate results in decreased activity of ACMSD protein] which results in increased abundance of Niacin and Dibutyl Phthalate affects the reaction [ACMSD protein affects the abundance of Niacin] | CTD | PMID:12036039 | Acmsd | Rat | O-methyleugenol | decreases expression | ISO | ACMSD (Homo sapiens) | 6480464 | methyleugenol results in decreased expression of ACMSD mRNA | CTD | PMID:32234424 | Acmsd | Rat | paracetamol | decreases expression | ISO | ACMSD (Homo sapiens) | 6480464 | Acetaminophen results in decreased expression of ACMSD mRNA | CTD | PMID:29067470 | Acmsd | Rat | pentanal | decreases expression | ISO | ACMSD (Homo sapiens) | 6480464 | pentanal results in decreased expression of ACMSD mRNA | CTD | PMID:26079696 | Acmsd | Rat | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Acmsd (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Pectins] results in increased expression of ACMSD mRNA | CTD | PMID:36331819 | Acmsd | Rat | phenformin | increases expression | EXP | | 6480464 | Phenformin results in increased expression of ACMSD mRNA | CTD | PMID:31324951 | Acmsd | Rat | PhIP | increases expression | EXP | | 6480464 | 2-amino-1-methyl-6-phenylimidazo(4 and 5-b)pyridine results in increased expression of ACMSD mRNA | CTD | PMID:33945839 | Acmsd | Rat | pirinixic acid | multiple interactions | ISO | Acmsd (Mus musculus) | 6480464 | HNF4A protein affects the reaction [pirinixic acid results in decreased expression of ACMSD mRNA] more ... | CTD | PMID:16807375 | Acmsd | Rat | pirinixic acid | decreases expression | EXP | | 6480464 | pirinixic acid results in decreased expression of ACMSD mRNA | CTD | PMID:17164430 and PMID:18320257 | Acmsd | Rat | pirinixic acid | multiple interactions | EXP | | 6480464 | MK-886 inhibits the reaction [pirinixic acid results in decreased expression of ACMSD mRNA] | CTD | PMID:18320257 | Acmsd | Rat | pirinixic acid | decreases activity | ISO | Acmsd (Mus musculus) | 6480464 | pirinixic acid results in decreased activity of ACMSD mRNA | CTD | PMID:16807375 | Acmsd | Rat | pirinixic acid | decreases expression | ISO | Acmsd (Mus musculus) | 6480464 | pirinixic acid results in decreased expression of ACMSD mRNA | CTD | PMID:16807375 | Acmsd | Rat | propanal | decreases expression | ISO | ACMSD (Homo sapiens) | 6480464 | propionaldehyde results in decreased expression of ACMSD mRNA | CTD | PMID:26079696 | Acmsd | Rat | pyrazine-2-carboxylic acid | decreases activity | EXP | | 6480464 | pyrazinoic acid metabolite results in decreased activity of ACMSD protein | CTD | PMID:12224625 | Acmsd | Rat | quinolinic acid | affects abundance | EXP | | 6480464 | ACMSD protein affects the abundance of Quinolinic Acid | CTD | PMID:17896587 | Acmsd | Rat | resveratrol | increases expression | EXP | | 6480464 | resveratrol results in increased expression of ACMSD mRNA | CTD | PMID:25905778 | Acmsd | Rat | rotenone | affects expression | EXP | | 6480464 | Rotenone affects the expression of ACMSD mRNA | CTD | PMID:28374803 | Acmsd | Rat | silicon dioxide | decreases expression | ISO | ACMSD (Homo sapiens) | 6480464 | Silicon Dioxide analog results in decreased expression of ACMSD mRNA | CTD | PMID:25895662 | Acmsd | Rat | sodium arsenite | decreases expression | ISO | ACMSD (Homo sapiens) | 6480464 | sodium arsenite results in decreased expression of ACMSD mRNA | CTD | PMID:29301061 | Acmsd | Rat | streptozocin | increases activity | EXP | | 6480464 | Streptozocin results in increased activity of ACMSD protein | CTD | PMID:12042425 | Acmsd | Rat | streptozocin | increases expression | EXP | | 6480464 | Streptozocin results in increased expression of ACMSD mRNA | CTD | PMID:12042425 | Acmsd | Rat | Tesaglitazar | decreases expression | EXP | | 6480464 | tesaglitazar results in decreased expression of ACMSD mRNA | CTD | PMID:21515302 | Acmsd | Rat | tetrachloromethane | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of ACMSD mRNA] | CTD | PMID:31150632 | Acmsd | Rat | tetrachloromethane | decreases expression | EXP | | 6480464 | Carbon Tetrachloride results in decreased expression of ACMSD mRNA | CTD | PMID:31150632 | Acmsd | Rat | trichloroethene | decreases expression | ISO | Acmsd (Mus musculus) | 6480464 | Trichloroethylene results in decreased expression of ACMSD mRNA | CTD | PMID:28973375 | Acmsd | Rat | triptonide | increases expression | ISO | Acmsd (Mus musculus) | 6480464 | triptonide results in increased expression of ACMSD mRNA | CTD | PMID:33045310 | Acmsd | Rat | valproic acid | decreases methylation | ISO | ACMSD (Homo sapiens) | 6480464 | Valproic Acid results in decreased methylation of ACMSD gene | CTD | PMID:29154799 | Acmsd | Rat | valproic acid | decreases expression | ISO | ACMSD (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of ACMSD mRNA | CTD | PMID:29154799 | Acmsd | Rat | zoledronic acid | decreases expression | ISO | ACMSD (Homo sapiens) | 6480464 | zoledronic acid results in decreased expression of ACMSD mRNA | CTD | PMID:24714768 | |