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Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (-)-epigallocatechin 3-gallate | multiple interactions | ISO | RGD:733406 | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in increased expression of CCNL1 mRNA | CTD | PMID:22079256 | (1->4)-beta-D-glucan | multiple interactions | ISO | RGD:733407 | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of CCNL1 mRNA | CTD | PMID:36331819 | 1,2-dimethylhydrazine | multiple interactions | EXP | | 6480464 | [APC protein affects the susceptibility to 1, 2-Dimethylhydrazine] which results in increased expression of CCNL1 mRNA | CTD | PMID:27840820 | 1,2-dimethylhydrazine | increases expression | ISO | RGD:733407 | 6480464 | 1, 2-Dimethylhydrazine results in increased expression of CCNL1 mRNA | CTD | PMID:22206623 | 17alpha-ethynylestradiol | affects expression | ISO | RGD:733407 | 6480464 | Ethinyl Estradiol affects the expression of CCNL1 mRNA | CTD | PMID:17555576 | 17alpha-ethynylestradiol | multiple interactions | ISO | RGD:733407 | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in decreased expression of CCNL1 mRNA | CTD | PMID:17942748 | 17alpha-ethynylestradiol | increases expression | ISO | RGD:733407 | 6480464 | Ethinyl Estradiol results in increased expression of CCNL1 mRNA | CTD | PMID:17942748 | 17beta-estradiol | decreases expression | EXP | | 6480464 | Estradiol results in decreased expression of CCNL1 mRNA | CTD | PMID:35192832 | 2,2',4,4'-Tetrabromodiphenyl ether | increases expression | ISO | RGD:733406 | 6480464 | 2 more ... | CTD | PMID:19095052 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | RGD:733406 | 6480464 | Tetrachlorodibenzodioxin affects the expression of CCNL1 mRNA | CTD | PMID:22298810 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | RGD:733407 | 6480464 | Tetrachlorodibenzodioxin results in increased expression of CCNL1 mRNA | CTD | PMID:21354282 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | RGD:733407 | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in decreased expression of CCNL1 mRNA | CTD | PMID:17942748 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | RGD:733407 | 6480464 | Tetrachlorodibenzodioxin affects the expression of CCNL1 mRNA | CTD | PMID:21570461 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | RGD:733407 | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of CCNL1 mRNA | CTD | PMID:17942748, PMID:19770486 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of CCNL1 mRNA | CTD | PMID:21215274 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of CCNL1 mRNA | CTD | PMID:15358164 more ... | 2-hydroxypropanoic acid | increases expression | ISO | RGD:733406 | 6480464 | Lactic Acid results in increased expression of CCNL1 mRNA | CTD | PMID:30851411 | 2-methylcholine | affects expression | ISO | RGD:733406 | 6480464 | beta-methylcholine affects the expression of CCNL1 mRNA | CTD | PMID:21179406 | 3H-1,2-dithiole-3-thione | decreases expression | EXP | | 6480464 | 1, 2-dithiol-3-thione results in decreased expression of CCNL1 mRNA | CTD | PMID:19162173 | 4-hydroxyphenyl retinamide | increases expression | ISO | RGD:733407 | 6480464 | Fenretinide results in increased expression of CCNL1 mRNA | CTD | PMID:28973697 | acetaldehyde | increases expression | ISO | RGD:733406 | 6480464 | Acetaldehyde results in increased expression of CCNL1 mRNA | CTD | PMID:23416264 | acrolein | multiple interactions | ISO | RGD:733406 | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of CCNL1 mRNA, [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in decreased expression of CCNL1 mRNA | CTD | PMID:32699268 | acrylamide | increases expression | EXP | | 6480464 | Acrylamide results in increased expression of CCNL1 mRNA | CTD | PMID:15749267 | aflatoxin B1 | increases expression | ISO | RGD:733407 | 6480464 | Aflatoxin B1 results in increased expression of CCNL1 mRNA | CTD | PMID:19770486 | aflatoxin B1 | decreases methylation | ISO | RGD:733406 | 6480464 | Aflatoxin B1 results in decreased methylation of CCNL1 gene | CTD | PMID:27153756 | aldehydo-D-glucose | increases expression | ISO | RGD:733407 | 6480464 | Glucose results in increased expression of CCNL1 mRNA | CTD | PMID:17178593 | all-trans-retinoic acid | increases expression | ISO | RGD:733406 | 6480464 | Tretinoin results in increased expression of CCNL1 mRNA | CTD | PMID:33167477 | alpha-pinene | multiple interactions | ISO | RGD:733406 | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of CCNL1 mRNA, [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in decreased expression of CCNL1 mRNA | CTD | PMID:32699268 | ammonium chloride | affects expression | EXP | | 6480464 | Ammonium Chloride affects the expression of CCNL1 mRNA | CTD | PMID:16483693 | antirheumatic drug | decreases expression | ISO | RGD:733406 | 6480464 | Antirheumatic Agents results in decreased expression of CCNL1 mRNA | CTD | PMID:24449571 | Aroclor 1254 | decreases expression | ISO | RGD:733407 | 6480464 | Chlorodiphenyl (54% Chlorine) results in decreased expression of CCNL1 mRNA | CTD | PMID:23650126 | azoxystrobin | multiple interactions | EXP | | 6480464 | [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of CCNL1 mRNA | CTD | PMID:33854195 | benzo[a]pyrene | increases expression | ISO | RGD:733407 | 6480464 | Benzo(a)pyrene results in increased expression of CCNL1 mRNA | CTD | PMID:22228805 | benzo[a]pyrene | affects methylation | ISO | RGD:733406 | 6480464 | Benzo(a)pyrene affects the methylation of CCNL1 promoter | CTD | PMID:27901495 | benzo[a]pyrene | multiple interactions | ISO | RGD:733407 | 6480464 | [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of CCNL1 mRNA | CTD | PMID:27858113 | benzo[b]fluoranthene | multiple interactions | ISO | RGD:733407 | 6480464 | [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of CCNL1 mRNA | CTD | PMID:27858113 | bis(2-chloroethyl) sulfide | affects expression | EXP | | 6480464 | Mustard Gas affects the expression of CCNL1 mRNA | CTD | PMID:15651846 | bis(2-chloroethyl) sulfide | increases expression | ISO | RGD:733407 | 6480464 | Mustard Gas results in increased expression of CCNL1 mRNA | CTD | PMID:15674844 | bisphenol A | increases expression | ISO | RGD:733407 | 6480464 | bisphenol A results in increased expression of CCNL1 mRNA | CTD | PMID:26063408 | bisphenol A | decreases expression | ISO | RGD:733407 | 6480464 | bisphenol A results in decreased expression of CCNL1 mRNA | CTD | PMID:32156529 | bisphenol A | decreases expression | ISO | RGD:733406 | 6480464 | bisphenol A results in decreased expression of CCNL1 mRNA | CTD | PMID:29275510 | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of CCNL1 mRNA | CTD | PMID:25181051, PMID:35192832 | butanal | increases expression | ISO | RGD:733406 | 6480464 | butyraldehyde results in increased expression of CCNL1 mRNA | CTD | PMID:26079696 | C60 fullerene | decreases expression | EXP | | 6480464 | fullerene C60 results in decreased expression of CCNL1 mRNA | CTD | PMID:19167457 | cadmium dichloride | increases expression | EXP | | 6480464 | Cadmium Chloride results in increased expression of CCNL1 mRNA | CTD | PMID:19010381 | caffeine | affects phosphorylation | ISO | RGD:733406 | 6480464 | Caffeine affects the phosphorylation of CCNL1 protein | CTD | PMID:35688186 | capsaicin | increases expression | EXP | | 6480464 | Capsaicin results in increased expression of CCNL1 mRNA | CTD | PMID:20349343 | CGP 52608 | multiple interactions | ISO | RGD:733406 | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to CCNL1 gene] | CTD | PMID:28238834 | chlorpyrifos | multiple interactions | EXP | | 6480464 | [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of CCNL1 mRNA | CTD | PMID:33854195 | chrysene | multiple interactions | ISO | RGD:733407 | 6480464 | [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of CCNL1 mRNA | CTD | PMID:27858113 | clozapine | increases expression | EXP | | 6480464 | Clozapine results in increased expression of CCNL1 mRNA | CTD | PMID:15860345 | cocaine | increases expression | EXP | | 6480464 | Cocaine results in increased expression of CCNL1 mRNA | CTD | PMID:16076954 | copper atom | increases expression | EXP | | 6480464 | Copper results in increased expression of CCNL1 mRNA | CTD | PMID:30556269 | copper(0) | increases expression | EXP | | 6480464 | Copper results in increased expression of CCNL1 mRNA | CTD | PMID:30556269 | copper(II) sulfate | increases expression | ISO | RGD:733406 | 6480464 | Copper Sulfate results in increased expression of CCNL1 mRNA | CTD | PMID:19549813 | coumarin | increases phosphorylation | ISO | RGD:733406 | 6480464 | coumarin results in increased phosphorylation of CCNL1 protein | CTD | PMID:35688186 | crocidolite asbestos | increases expression | ISO | RGD:733406 | 6480464 | Asbestos, Crocidolite results in increased expression of CCNL1 mRNA | CTD | PMID:18687144 | cyclosporin A | increases expression | ISO | RGD:733406 | 6480464 | Cyclosporine results in increased expression of CCNL1 mRNA | CTD | PMID:20106945, PMID:25562108 | cyclosporin A | decreases expression | ISO | RGD:733407 | 6480464 | Cyclosporine results in decreased expression of CCNL1 mRNA | CTD | PMID:19770486 | D-glucose | increases expression | ISO | RGD:733407 | 6480464 | Glucose results in increased expression of CCNL1 mRNA | CTD | PMID:17178593 | dibutyl phthalate | increases expression | EXP | | 6480464 | Dibutyl Phthalate results in increased expression of CCNL1 mRNA | CTD | PMID:21266533 | doxorubicin | increases expression | ISO | RGD:733407 | 6480464 | Doxorubicin results in increased expression of CCNL1 mRNA | CTD | PMID:25896364 | fluoranthene | multiple interactions | ISO | RGD:733407 | 6480464 | [1-methylanthracene co-treated with fluoranthene] results in increased expression of CCNL1 mRNA | CTD | PMID:28329830 | folic acid | decreases expression | ISO | RGD:733407 | 6480464 | Folic Acid results in decreased expression of CCNL1 mRNA | CTD | PMID:25629700 | formaldehyde | increases expression | ISO | RGD:733406 | 6480464 | Formaldehyde results in increased expression of CCNL1 mRNA | CTD | PMID:17938736, PMID:20655997 | formaldehyde | decreases expression | ISO | RGD:733406 | 6480464 | Formaldehyde results in decreased expression of CCNL1 mRNA | CTD | PMID:23649840 | gentamycin | increases expression | EXP | | 6480464 | Gentamicins results in increased expression of CCNL1 mRNA | CTD | PMID:22061828, PMID:33387578 | glucose | increases expression | ISO | RGD:733407 | 6480464 | Glucose results in increased expression of CCNL1 mRNA | CTD | PMID:17178593 | glyphosate | multiple interactions | EXP | | 6480464 | [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of CCNL1 mRNA | CTD | PMID:33854195 | haloperidol | increases expression | EXP | | 6480464 | Haloperidol results in increased expression of CCNL1 mRNA | CTD | PMID:15860345 | imidacloprid | multiple interactions | EXP | | 6480464 | [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of CCNL1 mRNA | CTD | PMID:33854195 | leflunomide | increases expression | ISO | RGD:733406 | 6480464 | leflunomide results in increased expression of CCNL1 mRNA | CTD | PMID:28988120 | leflunomide | increases expression | ISO | RGD:733407 | 6480464 | leflunomide results in increased expression of CCNL1 mRNA | CTD | PMID:19751817 | lipopolysaccharide | increases expression | EXP | | 6480464 | Lipopolysaccharides results in increased expression of CCNL1 mRNA | CTD | PMID:16415329 | lipopolysaccharide | multiple interactions | EXP | | 6480464 | Ranitidine promotes the reaction [Lipopolysaccharides results in increased expression of CCNL1 mRNA] | CTD | PMID:16415329 | methamphetamine | increases expression | EXP | | 6480464 | Methamphetamine results in increased expression of CCNL1 mRNA | CTD | PMID:19564919 | methyl methanesulfonate | decreases expression | ISO | RGD:733406 | 6480464 | Methyl Methanesulfonate results in decreased expression of CCNL1 mRNA | CTD | PMID:23649840 | methylisothiazolinone | increases expression | ISO | RGD:733406 | 6480464 | 2-methyl-4-isothiazolin-3-one results in increased expression of CCNL1 mRNA | CTD | PMID:31629900 | methylmercury chloride | decreases expression | ISO | RGD:733406 | 6480464 | methylmercuric chloride results in decreased expression of CCNL1 mRNA | CTD | PMID:28001369 | methylmercury chloride | increases expression | ISO | RGD:733406 | 6480464 | methylmercuric chloride results in increased expression of CCNL1 mRNA | CTD | PMID:28001369 | mono(2-ethyl-5-oxohexyl) phthalate | affects expression | ISO | RGD:733406 | 6480464 | mono(2-ethyl-5-oxohexyl)phthalate affects the expression of CCNL1 mRNA | CTD | PMID:34478338 | N1'-[2-[[5-[(dimethylamino)methyl]-2-furanyl]methylthio]ethyl]-N1-methyl-2-nitroethene-1,1-diamine | multiple interactions | EXP | | 6480464 | Ranitidine promotes the reaction [Lipopolysaccharides results in increased expression of CCNL1 mRNA] | CTD | PMID:16415329 | nefazodone | decreases expression | EXP | | 6480464 | nefazodone results in decreased expression of CCNL1 mRNA | CTD | PMID:24136188 | ozone | multiple interactions | ISO | RGD:733406 | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of CCNL1 mRNA more ... | CTD | PMID:32699268 | paracetamol | increases expression | ISO | RGD:733406 | 6480464 | Acetaminophen results in increased expression of CCNL1 mRNA | CTD | PMID:21420995 | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of CCNL1 mRNA | CTD | PMID:33387578 | paracetamol | affects expression | ISO | RGD:733407 | 6480464 | Acetaminophen affects the expression of CCNL1 mRNA | CTD | PMID:17562736 | paracetamol | decreases expression | ISO | RGD:733406 | 6480464 | Acetaminophen results in decreased expression of CCNL1 mRNA | CTD | PMID:22230336 | paraquat | increases expression | EXP | | 6480464 | Paraquat results in increased expression of CCNL1 mRNA | CTD | PMID:32680482 | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | RGD:733407 | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of CCNL1 mRNA | CTD | PMID:36331819 | phenobarbital | affects expression | ISO | RGD:733407 | 6480464 | Phenobarbital affects the expression of CCNL1 mRNA | CTD | PMID:23091169 | phenobarbital | decreases expression | ISO | RGD:733407 | 6480464 | Phenobarbital results in decreased expression of CCNL1 mRNA | CTD | PMID:19270015 | pirinixic acid | decreases expression | EXP | | 6480464 | pirinixic acid results in decreased expression of CCNL1 mRNA | CTD | PMID:19162173, PMID:22484513 | pirinixic acid | increases expression | ISO | RGD:733407 | 6480464 | pirinixic acid results in increased expression of CCNL1 mRNA | CTD | PMID:18445702 | potassium chromate | multiple interactions | ISO | RGD:733406 | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in increased expression of CCNL1 mRNA | CTD | PMID:22079256 | potassium chromate | increases expression | ISO | RGD:733406 | 6480464 | potassium chromate(VI) results in increased expression of CCNL1 mRNA | CTD | PMID:22079256 | rac-lactic acid | increases expression | ISO | RGD:733406 | 6480464 | Lactic Acid results in increased expression of CCNL1 mRNA | CTD | PMID:30851411 | ranitidine | multiple interactions | EXP | | 6480464 | Ranitidine promotes the reaction [Lipopolysaccharides results in increased expression of CCNL1 mRNA] | CTD | PMID:16415329 | silicon dioxide | increases expression | ISO | RGD:733406 | 6480464 | Silicon Dioxide results in increased expression of CCNL1 mRNA | CTD | PMID:25351596 | silicon dioxide | increases expression | ISO | RGD:733407 | 6480464 | Silicon Dioxide results in increased expression of CCNL1 mRNA | CTD | PMID:19073995 | silver atom | increases expression | ISO | RGD:733406 | 6480464 | Silver results in increased expression of CCNL1 mRNA | CTD | PMID:26014281 | silver(0) | increases expression | ISO | RGD:733406 | 6480464 | Silver results in increased expression of CCNL1 mRNA | CTD | PMID:26014281 | sodium arsenite | increases expression | ISO | RGD:733407 | 6480464 | sodium arsenite results in increased expression of CCNL1 mRNA | CTD | PMID:36209798 | Soman | increases expression | EXP | | 6480464 | Soman results in increased expression of CCNL1 mRNA | CTD | PMID:19281266 | tamoxifen | affects expression | ISO | RGD:733407 | 6480464 | Tamoxifen affects the expression of CCNL1 mRNA | CTD | PMID:17555576 | tetrachloromethane | increases expression | ISO | RGD:733407 | 6480464 | Carbon Tetrachloride results in increased expression of CCNL1 mRNA | CTD | PMID:31919559 | tetraphene | decreases expression | ISO | RGD:733407 | 6480464 | benz(a)anthracene results in decreased expression of CCNL1 mRNA | CTD | PMID:26377693 | tetraphene | multiple interactions | ISO | RGD:733407 | 6480464 | [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in decreased expression of CCNL1 mRNA | CTD | PMID:27858113 | thiabendazole | multiple interactions | EXP | | 6480464 | [azoxystrobin co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Chlorpyrifos co-treated with glyphosate co-treated with imidacloprid co-treated with Thiabendazole] results in increased expression of CCNL1 mRNA | CTD | PMID:33854195 | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of CCNL1 mRNA | CTD | PMID:34492290 | titanium dioxide | decreases expression | ISO | RGD:733407 | 6480464 | titanium dioxide results in decreased expression of CCNL1 mRNA | CTD | PMID:23557971 | triptonide | increases expression | ISO | RGD:733407 | 6480464 | triptonide results in increased expression of CCNL1 mRNA | CTD | PMID:33045310 | trovafloxacin | increases expression | ISO | RGD:733407 | 6480464 | trovafloxacin results in increased expression of CCNL1 mRNA | CTD | PMID:35537566 | valproic acid | decreases methylation | ISO | RGD:733406 | 6480464 | Valproic Acid results in decreased methylation of CCNL1 gene | CTD | PMID:29154799 | valproic acid | decreases expression | ISO | RGD:733407 | 6480464 | Valproic Acid results in decreased expression of CCNL1 mRNA | CTD | PMID:15799026 more ... | valproic acid | decreases expression | ISO | RGD:733406 | 6480464 | Valproic Acid results in decreased expression of CCNL1 mRNA | CTD | PMID:23179753 | valproic acid | affects expression | ISO | RGD:733406 | 6480464 | Valproic Acid affects the expression of CCNL1 mRNA | CTD | PMID:25979313 | vinclozolin | increases expression | EXP | | 6480464 | vinclozolin results in increased expression of CCNL1 mRNA | CTD | PMID:23034163 | vincristine | decreases expression | ISO | RGD:733406 | 6480464 | Vincristine results in decreased expression of CCNL1 mRNA | CTD | PMID:23649840 | vitamin E | decreases expression | ISO | RGD:733406 | 6480464 | Vitamin E results in decreased expression of CCNL1 mRNA | CTD | PMID:19244175 | zinc atom | multiple interactions | ISO | RGD:733406 | 6480464 | [PCI 5002 co-treated with Zinc] results in increased expression of CCNL1 mRNA | CTD | PMID:18593933 | zinc(0) | multiple interactions | ISO | RGD:733406 | 6480464 | [PCI 5002 co-treated with Zinc] results in increased expression of CCNL1 mRNA | CTD | PMID:18593933 | |