Gtf2f2 (general transcription factor IIF subunit 2) - Rat Genome Database

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Gene: Gtf2f2 (general transcription factor IIF subunit 2) Rattus norvegicus
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Symbol: Gtf2f2
Name: general transcription factor IIF subunit 2
RGD ID: 620772
Description: Enables RNA polymerase II general transcription initiation factor activity. Involved in RNA polymerase II preinitiation complex assembly and transcription elongation by RNA polymerase II. Part of transcription factor TFIIH holo complex. Orthologous to human GTF2F2 (general transcription factor IIF subunit 2); PARTICIPATES IN RNA polymerase II transcription elongation pathway; RNA polymerase II transcription initiation pathway; INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: ATP-dependent helicase GTF2F2; general transcription factor IIF, polypeptide 2; general transcription factor IIF, polypeptide 2 (30kD subunit); Rap30; TFIIF-beta; transcription factor gamma; transcription initiation factor IIF subunit beta; transcription initiation factor RAP30
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81557,615,361 - 57,736,477 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1557,614,841 - 57,736,516 (-)EnsemblGRCr8
mRatBN7.21551,206,027 - 51,327,166 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1551,206,031 - 51,327,253 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1555,364,405 - 55,485,389 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01556,482,728 - 56,603,708 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01553,304,878 - 53,426,373 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01557,942,057 - 58,068,892 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1557,942,059 - 58,068,892 (-)Ensemblrn6Rnor6.0
Rnor_5.01561,647,679 - 61,771,945 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41556,803,445 - 56,925,046 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1550,832,708 - 50,953,647 (-)NCBICelera
RGSC_v3.11556,819,226 - 56,940,826 (-)NCBI
Cytogenetic Map15q11NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. The carboxyl terminus of RAP30 is similar in sequence to region 4 of bacterial sigma factors and is required for function. Garrett KP, etal., J Biol Chem 1992 Nov 25;267(33):23942-9.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. Structural insights into transcription initiation by RNA polymerase II. Grunberg S and Hahn S, Trends Biochem Sci. 2013 Dec;38(12):603-11. doi: 10.1016/j.tibs.2013.09.002. Epub 2013 Oct 11.
5. Isolation and nucleotide sequence of a rat cDNA homologous to human RAP30. Kobayashi Y, etal., Nucleic Acids Res 1992 Apr 25;20(8):1994.
6. Control of transcriptional elongation. Kwak H and Lis JT, Annu Rev Genet. 2013;47:483-508. doi: 10.1146/annurev-genet-110711-155440. Epub 2013 Sep 11.
7. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
8. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
9. A mammalian RNA polymerase II holoenzyme containing all components required for promoter-specific transcription initiation. Ossipow V, etal., Cell. 1995 Oct 6;83(1):137-46.
10. GOA pipeline RGD automated data pipeline
11. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
12. Comprehensive gene review and curation RGD comprehensive gene curation
13. Roles for both the RAP30 and RAP74 subunits of transcription factor IIF in transcription initiation and elongation by RNA polymerase II. Tan S, etal., J Biol Chem. 1994 Oct 14;269(41):25684-91.
Additional References at PubMed
PMID:8662660   PMID:9841876   PMID:12477932   PMID:16791210  


Genomics

Comparative Map Data
Gtf2f2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81557,615,361 - 57,736,477 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1557,614,841 - 57,736,516 (-)EnsemblGRCr8
mRatBN7.21551,206,027 - 51,327,166 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1551,206,031 - 51,327,253 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1555,364,405 - 55,485,389 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01556,482,728 - 56,603,708 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01553,304,878 - 53,426,373 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01557,942,057 - 58,068,892 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1557,942,059 - 58,068,892 (-)Ensemblrn6Rnor6.0
Rnor_5.01561,647,679 - 61,771,945 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41556,803,445 - 56,925,046 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1550,832,708 - 50,953,647 (-)NCBICelera
RGSC_v3.11556,819,226 - 56,940,826 (-)NCBI
Cytogenetic Map15q11NCBI
GTF2F2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381345,120,510 - 45,284,893 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1345,120,510 - 45,284,893 (+)Ensemblhg38GRCh38
GRCh371345,694,645 - 45,859,028 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361344,592,672 - 44,756,237 (+)NCBIBuild 36Build 36hg18NCBI36
Build 341344,592,671 - 44,756,237NCBI
Celera1326,750,737 - 26,914,361 (+)NCBICelera
Cytogenetic Map13q14.12-q14.13NCBI
HuRef1326,496,415 - 26,659,718 (+)NCBIHuRef
CHM1_11345,662,169 - 45,825,812 (+)NCBICHM1_1
T2T-CHM13v2.01344,340,562 - 44,504,949 (+)NCBIT2T-CHM13v2.0
Gtf2f2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391476,134,368 - 76,248,356 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1476,134,377 - 76,248,305 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381475,896,928 - 76,010,865 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1475,896,937 - 76,010,865 (-)Ensemblmm10GRCm38
MGSCv371476,296,744 - 76,410,672 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361474,631,523 - 74,745,016 (-)NCBIMGSCv36mm8
Celera1473,398,175 - 73,511,806 (-)NCBICelera
Cytogenetic Map14D3NCBI
cM Map1440.29NCBI
Gtf2f2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555182,912,259 - 3,064,298 (+)Ensembl
ChiLan1.0NW_0049555182,912,259 - 3,064,298 (+)NCBIChiLan1.0ChiLan1.0
GTF2F2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21444,636,224 - 44,803,976 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11335,699,384 - 35,865,988 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01326,286,305 - 26,452,302 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13197,619,461 - 197,784,798 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3197,619,461 - 197,784,798 (-)EnsemblpanPan2panpan1.1
GTF2F2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1225,757,445 - 5,904,725 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl225,757,960 - 5,904,814 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha225,746,258 - 5,893,477 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0225,874,727 - 6,021,679 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl225,874,742 - 6,021,674 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1225,656,913 - 5,804,112 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0225,720,078 - 5,867,540 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0225,725,554 - 5,872,788 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Gtf2f2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404945155,323,631 - 155,470,099 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367911,244,186 - 1,391,205 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049367911,244,224 - 1,390,659 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GTF2F2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1121,983,832 - 22,144,954 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11121,987,410 - 22,144,921 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
GTF2F2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1323,195,682 - 23,380,628 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl323,212,334 - 23,384,036 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366605720,681,850 - 20,850,290 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Gtf2f2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247489,703,846 - 9,863,300 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247489,703,846 - 9,863,320 (-)NCBIHetGla 1.0HetGla 1.0hetGla2

Variants

.
Variants in Gtf2f2
809 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:94
Count of miRNA genes:73
Interacting mature miRNAs:84
Transcripts:ENSRNOT00000044254
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
631273Lecl2Lens clarity QTL 20.001lens clarity trait (VT:0001304)age of onset/diagnosis of cataract (CMO:0001584)151059608955596089Rat
1300144Rf23Renal function QTL 233.61renal blood flow trait (VT:2000006)absolute change in renal vascular resistance (CMO:0001900)154063126898288169Rat
2300167Bmd63Bone mineral density QTL 635.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)151111114256111142Rat
1331729Rf42Renal function QTL 423.071kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)151736289773690657Rat
152025253Hrtrt24Heart rate QTL 243.82heart pumping trait (VT:2000009)152788577486257085Rat
724545Niddm54Non-insulin dependent diabetes mellitus QTL 540.02blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)155079449473699215Rat
10054130Srcrt8Stress Responsive Cort QTL 82.180.0085blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)152211793367117933Rat
1582227Gluco30Glucose level QTL 303.60.0003blood glucose amount (VT:0000188)absolute change in blood glucose level area under curve (CMO:0002034)152803066582262678Rat
1582228Epfw3Epididymal fat weight QTL 34.10.0002epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)152803066582262678Rat
2300173Bmd62Bone mineral density QTL 6212.80.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)151111114256111142Rat
1578646Bmd18Bone mineral density QTL 185.2femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)152280624098288169Rat
1578647Bmd17Bone mineral density QTL 174femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)152280624098288169Rat
61424Scl1Serum cholesterol level QTL 17.70.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)151672552880672115Rat
2293686Bmd36Bone mineral density QTL 367.40.0001femur strength trait (VT:0010010)femoral neck ultimate force (CMO:0001703)153361105871477291Rat
1598828Glom14Glomerulus QTL 142.5kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)153405413979054139Rat
2317750Glom26Glomerulus QTL 264.3urine protein amount (VT:0005160)urine protein level (CMO:0000591)151249614165205939Rat
2298549Neuinf12Neuroinflammation QTL 123.5nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)15155302115Rat
2293691Bmd37Bone mineral density QTL 376.60.0001femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)153361105871477291Rat
2293688Bss29Bone structure and strength QTL 295.310.0001femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)151111114256111142Rat
1582242Gluco28Glucose level QTL 283.30.0008blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)152803066582262678Rat
1578660Bss19Bone structure and strength QTL 194.3femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)152280624098288169Rat
1582244Bw79Body weight QTL 7940.0002epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)152803066582262678Rat
1582214Stl21Serum triglyceride level QTL 213.10.022blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)152803066582262678Rat

Markers in Region
D15Rat148  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81557,638,749 - 57,638,848 (+)Marker Load Pipeline
mRatBN7.21551,229,421 - 51,229,521 (+)MAPPERmRatBN7.2
Rnor_6.01557,965,340 - 57,965,439NCBIRnor6.0
Rnor_5.01561,670,962 - 61,671,061UniSTSRnor5.0
RGSC_v3.41556,826,721 - 56,826,821RGDRGSC3.4
RGSC_v3.41556,826,722 - 56,826,821UniSTSRGSC3.4
Celera1550,856,095 - 50,856,194UniSTS
RGSC_v3.11556,842,501 - 56,842,601RGD
SHRSP x BN Map1534.6299UniSTS
SHRSP x BN Map1534.6299RGD
Cytogenetic Map15q11UniSTS
RH144249  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21551,277,868 - 51,277,968 (+)MAPPERmRatBN7.2
Rnor_6.01558,019,812 - 58,019,911NCBIRnor6.0
Rnor_5.01561,722,724 - 61,722,823UniSTSRnor5.0
RGSC_v3.41556,876,064 - 56,876,163UniSTSRGSC3.4
Celera1550,904,358 - 50,904,457UniSTS
RH 3.4 Map15601.1UniSTS
Cytogenetic Map15q11UniSTS
RH133175  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21714,611,946 - 14,612,161 (+)MAPPERmRatBN7.2
Rnor_6.01714,461,656 - 14,461,870NCBIRnor6.0
Rnor_5.01716,523,620 - 16,523,834UniSTSRnor5.0
RGSC_v3.41720,562,546 - 20,562,760UniSTSRGSC3.4
Celera1714,352,286 - 14,352,500UniSTS
RH 3.4 Map17153.4UniSTS
Cytogenetic Map15q11UniSTS
Cytogenetic Map17p14UniSTS
RH133440  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21551,206,228 - 51,206,411 (+)MAPPERmRatBN7.2
Rnor_6.01557,942,259 - 57,942,441NCBIRnor6.0
Rnor_5.01561,647,881 - 61,648,063UniSTSRnor5.0
RGSC_v3.41556,803,647 - 56,803,829UniSTSRGSC3.4
Celera1550,832,910 - 50,833,092UniSTS
Cytogenetic Map15q11UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000044254   ⟹   ENSRNOP00000044668
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1557,615,363 - 57,736,262 (-)Ensembl
mRatBN7.2 Ensembl1551,206,031 - 51,327,253 (-)Ensembl
Rnor_6.0 Ensembl1557,942,059 - 58,068,892 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000160276   ⟹   ENSRNOP00000111607
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1557,614,841 - 57,736,516 (-)Ensembl
RefSeq Acc Id: NM_031042   ⟹   NP_112304
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81557,615,361 - 57,736,477 (-)NCBI
mRatBN7.21551,206,027 - 51,327,166 (-)NCBI
Rnor_6.01557,942,057 - 58,068,892 (-)NCBI
Rnor_5.01561,647,679 - 61,771,945 (-)NCBI
RGSC_v3.41556,803,445 - 56,925,046 (-)RGD
Celera1550,832,708 - 50,953,647 (-)RGD
Sequence:
RefSeq Acc Id: NP_112304   ⟸   NM_031042
- UniProtKB: Q01750 (UniProtKB/Swiss-Prot),   Q63489 (UniProtKB/TrEMBL),   A6HTU1 (UniProtKB/TrEMBL),   F7F6U3 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000044668   ⟸   ENSRNOT00000044254
Ensembl Acc Id: ENSRNOP00000111607   ⟸   ENSRNOT00000160276
Protein Domains
TFIIF beta subunit HTH   TFIIF beta subunit N-terminal

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q01750-F1-model_v2 AlphaFold Q01750 1-249 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13699836
Promoter ID:EPDNEW_R10359
Type:multiple initiation site
Name:Gtf2f2_1
Description:general transcription factor IIF subunit 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01558,068,929 - 58,068,989EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:620772 AgrOrtholog
BioCyc Gene G2FUF-13096 BioCyc
Ensembl Genes ENSRNOG00000029316 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000160276 ENTREZGENE
Gene3D-CATH 1.10.10.10 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7381243 IMAGE-MGC_LOAD
InterPro TFIIF_beta UniProtKB/Swiss-Prot
  TFIIF_beta_HTH UniProtKB/Swiss-Prot
  TFIIF_beta_N UniProtKB/Swiss-Prot
  TFIIF_interaction UniProtKB/Swiss-Prot
  WH-like_DNA-bd_sf UniProtKB/Swiss-Prot
  WH_DNA-bd_sf UniProtKB/Swiss-Prot
MGC_CLONE MGC:108542 IMAGE-MGC_LOAD
NCBI Gene 81674 ENTREZGENE
PANTHER GENERAL TRANSCRIPTION FACTOR IIF SUBUNIT 2 UniProtKB/Swiss-Prot
  PTHR10445 UniProtKB/Swiss-Prot
Pfam TFIIF_beta UniProtKB/Swiss-Prot
  TFIIF_beta_N UniProtKB/Swiss-Prot
PhenoGen Gtf2f2 PhenoGen
PIRSF TFIIF-beta UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000029316 RatGTEx
Superfamily-SCOP SSF46785 UniProtKB/Swiss-Prot
  SSF50916 UniProtKB/Swiss-Prot
UniProt A6HTU1 ENTREZGENE
  A6HTU2_RAT UniProtKB/TrEMBL
  A6HTU3_RAT UniProtKB/TrEMBL
  A6HTU5_RAT UniProtKB/TrEMBL
  F7F6U3 ENTREZGENE, UniProtKB/TrEMBL
  Q01750 ENTREZGENE
  Q63489 ENTREZGENE, UniProtKB/TrEMBL
  T2FB_RAT UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-02-25 Gtf2f2  general transcription factor IIF subunit 2  Gtf2f2  general transcription factor IIF, polypeptide 2  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-09-10 Gtf2f2  general transcription factor IIF, polypeptide 2    general transcription factor IIF, polypeptide 2 (30kD subunit)  Name updated 1299863 APPROVED
2002-08-07 Gtf2f2  general transcription factor IIF, polypeptide 2 (30kD subunit)      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_homology has similarity to bacterial sigma factors, especially the carboxyl-terminal regions 4.1 and 4.2 of SpoIIIC (Bacillus subtilis sigma k) 632949