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Gene: Fgfr1 (Fibroblast growth factor receptor 1) Rattus norvegicus
Symbol: Fgfr1
Name: Fibroblast growth factor receptor 1
Description: Exhibits cell adhesion molecule binding activity and signaling receptor binding activity. Involved in several processes, including cellular response to histamine; generation of neurons; and positive regulation of cell population proliferation. Localizes to nucleus; perinuclear region of cytoplasm; and plasma membrane. Used to study pulmonary hypertension. Biomarker of several diseases, including ischemia (multiple); mesangial proliferative glomerulonephritis; sciatic neuropathy; vascular dementia; and visual epilepsy. Human ortholog(s) of this gene implicated in several diseases, including Jackson-Weiss syndrome; bone disease (multiple); cleft lip; hematologic cancer (multiple); and hypogonadotropic hypogonadism (multiple). Orthologous to human FGFR1 (fibroblast growth factor receptor 1); PARTICIPATES IN cerium oxide nanoparticle response pathway; fibroblast growth factor signaling pathway; glypican signaling pathway; INTERACTS WITH 2-amino-2-deoxy-D-glucopyranose; 3,3',5-triiodo-L-thyronine; 6-propyl-2-thiouracil.
Type: protein-coding
Also known as: basic fibroblast growth factor receptor 1; bFGF-R; bFGF-R-1; c-fgr; FGF receptor-1; FGFR-1; MFR; proto-oncogene c-Fgr
Homo sapiens (human) : FGFR1 (fibroblast growth factor receptor 1)  HGNC  Alliance
Mus musculus (house mouse) : Fgfr1 (fibroblast growth factor receptor 1)  MGI  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Fgfr1 (fibroblast growth factor receptor 1)
Pan paniscus (bonobo/pygmy chimpanzee) : FGFR1 (fibroblast growth factor receptor 1)
Canis lupus familiaris (dog) : FGFR1 (fibroblast growth factor receptor 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Fgfr1 (fibroblast growth factor receptor 1)
Sus scrofa (pig) : FGFR1 (fibroblast growth factor receptor 1)
Chlorocebus sabaeus (African green monkey) : FGFR1 (fibroblast growth factor receptor 1)
Heterocephalus glaber (naked mole-rat) : Fgfr1 (fibroblast growth factor receptor 1)
more info ...
Related Pseudogenes: Fgfr1-ps1  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.01671,265,390 - 71,319,046 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1671,266,248 - 71,319,449 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01670,924,716 - 70,977,998 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41670,869,974 - 70,910,045 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11670,870,238 - 70,910,310 (-)NCBI
Celera1664,402,647 - 64,442,189 (-)NCBICelera
Cytogenetic Map16q12.4NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants (Rnor 6.0)

Additional Information

External Database Links
Nomenclature History
More on Fgfr1
Alliance Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 620713
Created: 2002-08-06
Species: Rattus norvegicus
Last Modified: 2020-08-20
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.