Cd55 (CD55 molecule (Cromer blood group))

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Gene: Cd55 (CD55 molecule (Cromer blood group)) Rattus norvegicus

Analyze

Symbol:

Cd55

Name:

CD55 molecule (Cromer blood group)

RGD ID:

620651

Description:

Exhibits enzyme inhibitor activity. Involved in several processes, including maternal process involved in parturition; negative regulation of complement activation; and spermatogenesis. Localizes to apical plasma membrane. Used to study neuroblastoma and proteinuria. Human ortholog(s) of this gene implicated in prostate cancer and protein-losing enteropathy. Orthologous to human CD55 (CD55 molecule (Cromer blood group)); PARTICIPATES IN complement system pathway; coagulation cascade pathway; myocarditis pathway; INTERACTS WITH 1,3-dinitrobenzene; 17alpha-ethynylestradiol; 17beta-estradiol.

Type:

protein-coding

RefSeq Status:

VALIDATED

Also known as:

CD55 antigen; CD55 molecule, decay accelerating factor for complement; complement decay-accelerating factor; Daf; Daf1; decay accelarating factor 1; decay accelerating factor 1; decay accelerating factor GPI-form; decay-accelarating factor; glycosylphophatidylinositol-anchored form

RGD Orthologs

Human

Mouse

Chinchilla

Bonobo

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

Allele / Splice:

Cd55^em6Mcwi Cd55^em4Mcwi

Genetic Models:

SD-Cd55^em4Mcwi SD-Cd55^em6Mcwi

Latest Assembly:

Rnor_6.0 - RGSC Genome Assembly v6.0

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	13	41,857,242 - 41,885,966 (-)	NCBI
Rnor_6.0 Ensembl	13	47,126,741 - 47,154,292 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_6.0	13	47,125,156 - 47,153,557 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_5.0	13	52,177,543 - 52,206,137 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	13	43,322,246 - 43,348,334 (-)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	13	43,344,956 - 43,362,318 (-)	NCBI
Celera	13	42,209,852 - 42,236,220 (-)	NCBI		Celera
Cytogenetic Map	13	q13	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

amphetamine abuse (ISO)

autistic disorder (ISO)

breast cancer (ISO)

cervical cancer (ISO)

endometrial adenocarcinoma (ISO)

endometriosis (ISO)

gastrointestinal stromal tumor (ISO)

neuroblastoma (IMP)

parathyroid carcinoma (ISO)

prostate cancer (ISO)

protein-losing enteropathy (ISO)

proteinuria (IMP)

Reperfusion Injury (IEP)

Viral Myocarditis (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(-)-anisomycin (ISO)

(-)-demecolcine (ISO)

1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane (ISO)

1,2-dichloroethane (ISO)

1,2-dimethylhydrazine (ISO)

1,3-dinitrobenzene (EXP)

1-naphthyl isothiocyanate (ISO)

17alpha-ethynylestradiol (EXP,ISO)

17beta-estradiol (EXP,ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,3,7,8-Tetrachlorodibenzofuran (EXP)

3,3',4,4',5-pentachlorobiphenyl (EXP)

3-isobutyl-1-methyl-7H-xanthine (ISO)

3-methylcholanthrene (ISO)

4,4'-sulfonyldiphenol (ISO)

4-(ethoxymethylene)-2-phenyloxazol-5-one (ISO)

4-hydroxyphenyl retinamide (ISO)

6-propyl-2-thiouracil (EXP)

acetylsalicylic acid (EXP)

acrylamide (EXP)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

AM-251 (ISO)

ammonium chloride (EXP)

amphetamine (EXP)

arsenite(3-) (ISO)

arsenous acid (ISO)

benzo[a]pyrene (ISO)

benzo[a]pyrene diol epoxide I (ISO)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

butanal (ISO)

butyric acid (EXP)

cadmium selenide (ISO)

carbamazepine (ISO)

carbon nanotube (ISO)

chloroprene (ISO)

chrysene (ISO)

cisplatin (ISO)

cobalt dichloride (ISO)

colforsin daropate hydrochloride (ISO)

copper atom (EXP)

copper(0) (EXP)

copper(II) sulfate (ISO)

coumestrol (ISO)

crocidolite asbestos (ISO)

curcumin (ISO)

cyclosporin A (ISO)

deoxynivalenol (ISO)

dexamethasone (ISO)

dextran sulfate (ISO)

diarsenic trioxide (ISO)

dibutyl phthalate (EXP)

diclofenac (ISO)

dicrotophos (ISO)

diethylstilbestrol (EXP)

diuron (EXP)

dopamine (EXP)

dorsomorphin (ISO)

doxorubicin (ISO)

endosulfan (EXP)

Enterolactone (ISO)

etoposide (ISO)

fenoldopam (EXP)

flavonoids (EXP)

flutamide (EXP)

folic acid (ISO)

furan (EXP)

indometacin (ISO)

ionomycin (ISO)

lead(0) (ISO)

lead(2+) (ISO)

leflunomide (ISO)

lipopolysaccharide (ISO)

mercury dichloride (ISO)

metam (ISO)

methamphetamine (ISO)

methotrexate (ISO)

methyl methanesulfonate (ISO)

methylisothiazolinone (ISO)

methylmercury chloride (ISO)

mitoxantrone (ISO)

N-methyl-4-phenylpyridinium (EXP,ISO)

panobinostat (ISO)

paracetamol (ISO)

perfluorooctanoic acid (ISO)

phenobarbital (ISO)

phytoestrogen (ISO)

pirinixic acid (ISO)

piroxicam (ISO)

potassium dichromate (ISO)

propanal (ISO)

quercetin (ISO)

SB 431542 (ISO)

silicon dioxide (ISO)

silver atom (ISO)

silver(0) (ISO)

sodium arsenite (ISO)

sulfasalazine (EXP)

sunitinib (ISO)

T-2 toxin (ISO)

tamoxifen (ISO)

tert-butyl hydroperoxide (ISO)

testosterone (EXP)

thapsigargin (ISO)

titanium dioxide (ISO)

toluene 2,4-diisocyanate (ISO)

torcetrapib (ISO)

Tributyltin oxide (ISO)

triptonide (ISO)

troglitazone (ISO)

tunicamycin (ISO)

urethane (ISO)

valproic acid (ISO)

vincristine (ISO)

zinc atom (ISO)

zinc(0) (ISO)

zoledronic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

maternal process involved in parturition (IEP)

negative regulation of catalytic activity (IEA)

negative regulation of complement activation (IDA,ISO)

negative regulation of complement activation, classical pathway (IBA)

positive regulation of CD4-positive, alpha-beta T cell activation (ISO)

positive regulation of CD4-positive, alpha-beta T cell proliferation (ISO)

positive regulation of cytosolic calcium ion concentration (ISO)

positive regulation of T cell cytokine production (ISO)

regulation of complement activation (ISO)

regulation of complement activation, classical pathway (ISO)

regulation of complement-dependent cytotoxicity (ISO)

regulation of lipopolysaccharide-mediated signaling pathway (ISO)

response to peptide hormone (IEP)

spermatogenesis (IEP)

T cell mediated immunity (IBA)

viral entry into host cell (IEA)

Cellular Component

apical plasma membrane (IDA)

cell surface (ISO)

external side of plasma membrane (ISO)

membrane raft (ISO)

plasma membrane (IBA,ISO)

sperm midpiece (ISO)

Molecular Function

enzyme inhibitor activity (IDA)

lipid binding (ISO)

protein binding (ISO)

virus receptor activity (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

coagulation cascade pathway (IEA)

complement system pathway (IDA,IEA)

myocarditis pathway (IEA)

References

References - curated


1.	Bao L, etal., Kidney Int. 2002 Dec;62(6):2010-21.
2.	Berry LJ, etal., Prostate. 2008 May 1;68(6):577-87.
3.	Chen S, etal., Cancer Res. 2000 Jun 1;60(11):3013-8.
4.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
5.	Gieske MC, etal., J Endocrinol. 2005 Aug;186(2):303-13.
6.	Girotti M and Zingg HH, Endocrinology. 2003 Jun;144(6):2254-65.
7.	GOA data from the GO Consortium
8.	Harris CL, etal., Immunology. 2000 Aug;100(4):462-70.
9.	Hinchliffe SJ, etal., J Immunol 1998 Nov 15;161(10):5695-703.
10.	Huang Y, etal., Inflammation. 2018 Feb;41(1):232-239. doi: 10.1007/s10753-017-0681-7.
11.	Ikeda J, etal., Clin Cancer Res. 2008 Aug 1;14(15):4780-6.
12.	Loberg RD, etal., Neoplasia. 2006 Jan;8(1):69-78.
13.	Madjd Z, etal., Clin Cancer Res. 2004 Apr 15;10(8):2797-803.
14.	MGD data from the GO Consortium
15.	Miwa T, etal., Immunogenetics 2000 Feb;51(2):129-37.
16.	Mizuno M, etal., Mol Immunol. 2007 Mar;44(7):1613-22. Epub 2006 Sep 27.
17.	NCBI rat LocusLink and RefSeq merged data July 26, 2002
18.	Nowicki S, etal., Am J Reprod Immunol. 2001 Aug;46(2):144-8.
19.	Pipeline to import KEGG annotations from KEGG into RGD
20.	Ramlall V, etal., Nat Med. 2020 Aug 3. pii: 10.1038/s41591-020-1021-2. doi: 10.1038/s41591-020-1021-2.
21.	RGD automated import pipeline for gene-chemical interactions
22.	Simpson KL, etal., Am J Pathol. 1997 Nov;151(5):1455-67.
23.	Wang W, etal., J Urol. 2010 Jun;183(6):2424-31. Epub 2010 Apr 18.
24.	Yanagawa B, etal., Lab Invest. 2003 Jan;83(1):75-85.

Additional References at PubMed

PMID:6211481	PMID:7525274	PMID:8223854	PMID:9892684	PMID:11313396	PMID:12477932	PMID:12731067	PMID:15907827	PMID:16818763	PMID:17166698	PMID:17826908	PMID:18064521
PMID:18947875	PMID:19199708	PMID:19299737	PMID:20458337	PMID:23376485	PMID:23533145	PMID:24377861	PMID:25284781	PMID:27662796	PMID:28657829

Genomics

Comparative Map Data

Cd55
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	13	41,857,242 - 41,885,966 (-)	NCBI
Rnor_6.0 Ensembl	13	47,126,741 - 47,154,292 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_6.0	13	47,125,156 - 47,153,557 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_5.0	13	52,177,543 - 52,206,137 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	13	43,322,246 - 43,348,334 (-)	NCBI	RGSC3.4		rn4	RGSC3.4
RGSC_v3.1	13	43,344,956 - 43,362,318 (-)	NCBI
Celera	13	42,209,852 - 42,236,220 (-)	NCBI		Celera
Cytogenetic Map	13	q13	NCBI

CD55
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38.p13 Ensembl	1	207,321,532 - 207,386,804 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh38.p13 Ensembl	1	207,321,376 - 207,386,804 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh38	1	207,321,674 - 207,360,966 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh37	1	207,495,023 - 207,534,311 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	205,561,488 - 205,600,470 (+)	NCBI	NCBI36		hg18	NCBI36
Build 34	1	203,883,259 - 203,922,241	NCBI
Celera	1	180,747,405 - 180,786,905 (+)	NCBI
Cytogenetic Map	1	q32.2	NCBI
HuRef	1	178,191,283 - 178,230,783 (+)	NCBI		HuRef
CHM1_1	1	208,767,582 - 208,807,063 (+)	NCBI		CHM1_1

Cd55
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	1	130,357,526 - 130,392,746 (-)	NCBI	GRCm39		mm39
GRCm39 Ensembl	1	130,366,764 - 130,390,481 (-)	Ensembl
GRCm38	1	130,429,798 - 130,465,009 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	1	130,439,027 - 130,462,744 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	1	132,335,606 - 132,359,317 (-)	NCBI	GRCm37		mm9	NCBIm37
MGSCv36	1	132,267,758 - 132,290,230 (-)	NCBI			mm8
Celera	1	133,067,523 - 133,091,208 (-)	NCBI		Celera
Cytogenetic Map	1	E4	NCBI
cM Map	1	56.89	NCBI

Cd55
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0	NW_004955406	42,773,368 - 42,796,205 (+)	NCBI	ChiLan1.0	ChiLan1.0

CD55
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	1	187,201,195 - 187,240,350 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	1	187,201,081 - 187,240,350 (+)	Ensembl	panpan1.1		panPan2
Mhudiblu_PPA_v0	1	182,923,369 - 182,962,518 (+)	NCBI	Mhudiblu_PPA_v0		panPan3

CD55
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	7	6,361,037 - 6,396,063 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	7	6,360,964 - 6,386,226 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	7	5,923,634 - 5,949,508 (+)	NCBI
ROS_Cfam_1.0	7	6,049,135 - 6,075,038 (+)	NCBI
UMICH_Zoey_3.1	7	5,982,465 - 6,008,341 (+)	NCBI
UNSW_CanFamBas_1.0	7	6,084,489 - 6,110,584 (+)	NCBI
UU_Cfam_GSD_1.0	7	6,125,081 - 6,150,968 (+)	NCBI

Cd55
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409344	68,104,286 - 68,123,978 (-)	NCBI
SpeTri2.0	NW_004936557	5,344,373 - 5,364,234 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

CD55
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1	9	67,933,069 - 67,960,380 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	9	74,368,906 - 74,393,140 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3
Sscrofa10.2	9	74,313,866 - 74,314,997 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

CD55
(Chlorocebus sabaeus - African green monkey)

Vervet Assembly	Chr	Position (strand)	Source	Genome Browsers
Vervet Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	25	22,055,138 - 22,092,472 (-)	NCBI
ChlSab1.1 Ensembl	25	22,073,629 - 22,092,173 (-)	Ensembl

Cd55
(Heterocephalus glaber - naked mole-rat)

Molerat Assembly	Chr	Position (strand)	Source	Genome Browsers
Molerat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624807	4,252,676 - 4,274,828 (-)	NCBI

Position Markers

RH132379

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	13	41,859,101 - 41,859,262 (+)	MAPPER
Rnor_6.0	13	47,126,905 - 47,127,065	NCBI	Rnor6.0
Rnor_5.0	13	52,179,265 - 52,179,425	UniSTS	Rnor5.0
RGSC_v3.4	13	43,321,762 - 43,321,922	UniSTS	RGSC3.4
Celera	13	42,209,368 - 42,209,528	UniSTS
RH 3.4 Map	13	108.0	UniSTS
Cytogenetic Map	13	q13	UniSTS

RH139453

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	13	41,868,081 - 41,868,201 (+)	MAPPER
Rnor_6.0	13	47,135,774 - 47,135,893	NCBI	Rnor6.0
Rnor_5.0	13	52,188,134 - 52,188,253	UniSTS	Rnor5.0
RGSC_v3.4	13	43,330,741 - 43,330,860	UniSTS	RGSC3.4
Celera	13	42,218,349 - 42,218,468	UniSTS
RH 3.4 Map	13	108.8	UniSTS
Cytogenetic Map	13	q13	UniSTS

RH141317

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	13	41,868,081 - 41,868,288 (+)	MAPPER
Rnor_6.0	13	47,135,774 - 47,135,980	NCBI	Rnor6.0
Rnor_5.0	13	52,188,134 - 52,188,340	UniSTS	Rnor5.0
RGSC_v3.4	13	43,330,741 - 43,330,947	UniSTS	RGSC3.4
Celera	13	42,218,349 - 42,218,555	UniSTS
Cytogenetic Map	13	q13	UniSTS

QTLs in Region (Rnor_6.0)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
738036	Lnnr4	Liver neoplastic nodule remodeling QTL 4	3.64		liver integrity trait (VT:0010547)	liver remodeling tumorous lesion number (CMO:0001461)	13	1	47622148	Rat
1354666	Bp244	Blood pressure QTL 244	4.9		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	13	1	107975663	Rat
1354666	Bp244	Blood pressure QTL 244	4.9		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	13	1	107975663	Rat
1354666	Bp244	Blood pressure QTL 244	4.9		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	1	107975663	Rat
61339	Bp24	Blood pressure QTL 24		0.05	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	9016742	50513953	Rat
1581554	Pur11	Proteinuria QTL 11			urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	13	9016906	82995569	Rat
1581573	Uae36	Urinary albumin excretion QTL 36			urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	13	9016906	82995569	Rat
1581570	Eae17	Experimental allergic encephalomyelitis QTL 17	4.1		nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)	13	12193394	108478121	Rat
9589141	Insul28	Insulin level QTL 28	10.82	0.001	blood insulin amount (VT:0001560)	plasma insulin level (CMO:0000342)	13	14096330	59096330	Rat
7411662	Foco29	Food consumption QTL 29	20.8	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	13	14096330	59096330	Rat
1300163	Cardf1	Cardiac cell morphology QTL 1	4.18		aorta morphology trait (VT:0000272)	artery lesion measurement (CMO:0000975)	13	14441582	50799665	Rat
2302275	Gluco37	Glucose level QTL 37	3.8		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	13	14441582	51577031	Rat
2317040	Aia21	Adjuvant induced arthritis QTL 21	2.75		joint integrity trait (VT:0010548)	left rear ankle joint diameter (CMO:0002149)	13	14624631	59624631	Rat
2317046	Aia8	Adjuvant induced arthritis QTL 8	3.9700000286102295		joint integrity trait (VT:0010548)	left rear ankle joint diameter (CMO:0002149)	13	14624631	59624631	Rat
631645	Bp121	Blood pressure QTL 121	3.3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	19810814	64810814	Rat
9589164	Gluco66	Glucose level QTL 66	6.67	0.001	blood glucose amount (VT:0000188)	plasma glucose level (CMO:0000042)	13	20052477	65052477	Rat
1331784	Bp222	Blood pressure QTL 222	2.944		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	13	21482481	58537177	Rat
7207885	Glom27	Glomerulus QTL 27	3.9		kidney glomerulus integrity trait (VT:0010546)	kidney crescentic glomeruli count to kidney normal glomeruli count ratio (CMO:0002139)	13	24502279	108770533	Rat
61391	Bp5	Blood pressure QTL 5	5.6		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	13	28008338	73008338	Rat
70170	Eae14	Experimental allergic encephalomyelitis QTL 14		0.0024	nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)	13	28584452	73584452	Rat
1558644	Cm45	Cardiac mass QTL 45	3.6	0.002	heart mass (VT:0007028)	heart wet weight (CMO:0000069)	13	29076934	74076934	Rat
6893338	Cm76	Cardiac mass QTL 76	0	0.99	heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	13	29076934	74076934	Rat
1354621	Rf47	Renal function QTL 47	3.7		kidney renin amount (VT:0010559)	kidney renin level (CMO:0002166)	13	35301263	107975663	Rat
2301962	Cm72	Cardiac mass QTL 72	4.12		heart left ventricle mass (VT:0007031)	heart left ventricle weight (CMO:0000776)	13	36147533	64868393	Rat
70181	BpQTLcluster11	Blood pressure QTL cluster 11	6.922		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	13	36147533	99968921	Rat
70181	BpQTLcluster11	Blood pressure QTL cluster 11	6.922		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	36147533	99968921	Rat
70181	BpQTLcluster11	Blood pressure QTL cluster 11	6.922		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	13	36147533	99968921	Rat
70181	BpQTLcluster11	Blood pressure QTL cluster 11	6.922		arterial blood pressure trait (VT:2000000)	absolute change in mean arterial blood pressure (CMO:0000533)	13	36147533	99968921	Rat
2303563	Bw89	Body weight QTL 89	6		body mass (VT:0001259)	body weight (CMO:0000012)	13	37346348	82346348	Rat
61340	Bp25	Blood pressure QTL 25	4.2	0.004	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	39372927	84372927	Rat
10755495	Bp387	Blood pressure QTL 387	3.78		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	39501300	93652524	Rat
2292232	Pur16	Proteinuria QTL 16	17.2		total urine protein amount (VT:0000032)	urine protein level (CMO:0000591)	13	41060057	47227923	Rat
4889861	Pur29	Proteinuria QTL 29	13.8	0.005	total urine protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	13	42310744	86833540	Rat
1331750	Bp220	Blood pressure QTL 220	2.98		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	13	42310744	87310744	Rat
70220	Bp55	Blood pressure QTL 55	5.75		arterial blood pressure trait (VT:2000000)	blood pressure measurement (CMO:0000003)	13	42508345	87508345	Rat
61349	Bp31	Blood pressure QTL 31	5.75		arterial blood pressure trait (VT:2000000)	blood pressure measurement (CMO:0000003)	13	42508345	87508345	Rat
1549897	Stresp12	Stress response QTL 12	3.35		stress-related behavior trait (VT:0010451)	number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)	13	43575717	88575717	Rat
619615	Bp80	Blood pressure QTL 80		0.0354	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	13	45676629	90676629	Rat
2303032	Bp328	Blood pressure QTL 328			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	13	46444570	50799665	Rat

Genetic Models

This gene Cd55 is modified in the following models/strains

SD-Cd55^em4Mcwi

SD-Cd55^em6Mcwi

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	227
Count of miRNA genes:	155
Interacting mature miRNAs:	183
Transcripts:	ENSRNOT00000005284
Prediction methods:	Microtar, Miranda, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	3	6	16	16	4	16	4	6		10	23	11	4
Low		37	24	8	15	8	4	5	74	25	18		4
Below cutoff			17	17		17

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_022269	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006249717	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006249719	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006249723	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008769498	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017598923	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017598924	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039091062	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039091063	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AB026900	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AB026901	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AB026902	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AB026903	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AB026904	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AB026905	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AB032395	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AB032396	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AB294577	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AB294578	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AC127764	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AF039583	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AF039584	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC061869	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CB610207	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473958	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000242	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSRNOT00000005284 ⟹ ENSRNOP00000005284

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	13	47,126,741 - 47,154,292 (-)	Ensembl

RefSeq Acc Id:

NM_022269 ⟹ NP_071605

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	13	41,859,586 - 41,885,831 (-)	NCBI
Rnor_6.0	13	47,127,278 - 47,153,521 (-)	NCBI
Rnor_5.0	13	52,177,543 - 52,206,137 (-)	NCBI
RGSC_v3.4	13	43,322,246 - 43,348,334 (-)	RGD
Celera	13	42,209,852 - 42,236,220 (-)	RGD

Sequence:

show sequence

TAACCCTGGCTCAAAACAGCTCCAGCCGCAGCCGGGCACCGTCTCTTCTACCTGGGGCTATGAT
CCGCACGCGGGCGCCGGGGACTCGGGCACCGCCGCCGCCGCCGCTGCTGCTGTCGCTGTCGCTG
CTGCTGCTGCTGCTGTCCCCGACTGTAAGCGGAGACTGCGGCCCACCTCCAGACATTCCTAATG
CCACGCCAAACTCGGGTAAACACACCAAGTTTGCCCACCAAAGCCAAGTGACATATTCGTGTAA
TAAGGGCTTCAAACAAATTCCAGACAAGCCAAACACAGTGGTCTGCCTTGAAAATGACCAATGG
TCTAACTACGAAACTTTCTGTAATAAAACCTGTAGTGCTCCACTGAGACTGAATTATGCATCCC
TCAAAAAGGAGTATCGTAACATGAATTTTTTCCCAATTGGCACCACTGTGGAATTTGAGTGTCG
GCCAGGATTTCAAAAAGTAACTTCACGCACAGGAAAATCAACTTGCCTTGAGGAATTAGTATGG
TCTCCAGTTGTTGAATTTTGTAAAAAAAGAGCATGCCCTAATCCTAGAGAACTGAAAAATGGTC
ACATCAACATACCAACTGACATATTATTCGGATCAGAAATAATCTTCTCATGCGACAAAGGGTA
CAAGCTGGTCGGTGTAACTTCTACATTCTGTTCTATTACGGGGAATGCTGTGGACTGGGATGAC
GTATTTCCAGTGTGCACAACAATTTTTTGTCCAGACCCACCAAAAATCAATAATGGAAGAATTC
GAGAGGAAAGCGACTCCTACGCATATAGACAGTCGGTGACCTATTCCTGTGACCAAGGCTTCAT
TCTGGTTGGAAATTCTTCCGTTCATTGTACTCTGAACGGTGAAGTAGGAGAATGGAGTAGTGCA
CCACCCAAGTGCATAGAGAGACACAAGGTCCCAACTAAGACCCCACCAGAAGTTGATATTCCAA
GTACAATGCCTCATGAATCCACCTTAATTAATTTTCCAAGTACAAGAGCCCCACTGTCTCATAA
ACCCACTACAGTTAAAGTTCCAGGTACAAGAGTCAAACCAACGTCTCACAAGCCCACTGAAGTT
AAAGTTCCAGCAACACAGCATGTACCTGTTTCCAAGACAACGGTACGTCATCCAACGAGAACAT
CTAAAGACAGAGGAGAGTCTAATTCAGGTGGTGACCATTTTATATATGGACATACATGTTTAAT
AACCATGACAATTTTGCATGTGATGCTCTTACTCACTGGCTAGTTGACGTAGCCAACGAAGAGT
TAAGAAGAAAGTATATACAACCACTGAGAATACTTCTAGTTTGTTAGAATGTCCAGGAAGAATG
GATACAATAAATTTAATAGTGTTGTTGGTTCTGTATGCTGTCATCGTCTTGAAGGTGTGCTAGA
AATGATAACAAAGCAAGAAGAAAGGAGGTTGTCTGGAATGGTCTTTTCAATGCATATAAGTCTC
TTGAAAATATTTCAAAACTAGACAAATTCACAATGTTGTGTAGTATCTTTTCTAAAAAAAAGTG
TGGGAAAGTGTAGAAAATTTTCAGGGGAGAGGGAAATCATGATTTCTTAGGCTAGATCTATCCT
GTTATTCTAGCTTACAATAAAAAATAGGAAGCTAAAAATACTGATGAGATTGCAAAAGTAAAAG
ACCCCAAACGAAATTTCCTTCCTTGTAAACCGAATTGCTAGAGCTGGGACATTCTTATTTAACC
CTTGACCTGAAGGCATTTTCCTTTCTACTCTGTATTGGCAAACTGTTATAAAGGAAGAGCATGC
TAACAAACCAGTAGTAGGACAGGAAAAGAGCTCACTTGGTGCAG

hide sequence

RefSeq Acc Id:

XM_006249717 ⟹ XP_006249779

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	13	41,866,378 - 41,885,889 (-)	NCBI
Rnor_6.0	13	47,135,701 - 47,153,550 (-)	NCBI
Rnor_5.0	13	52,177,543 - 52,206,137 (-)	NCBI

Sequence:

show sequence

CCCGCCCCGCCCCTCCGCAGCCATTCAATTAACCCTGGCTCAAAACAGCTCCAGCCGCAGCCGG
GCACCGTCTCTTCTACCTGGGGCTATGATCCGCACGCGGGCGCCGGGGACTCGGGCACCGCCGC
CGCCGCCGCTGCTGCTGTCGCTGTCGCTGCTGCTGCTGCTGCTGTCCCCGACTGTAAGCGGAGA
CTGCGGCCCACCTCCAGACATTCCTAATGCCACGCCAAACTCGGGTAAACACACCAAGTTTGCC
CACCAAAGCCAAGTGACATATTCGTGTAATAAGGGCTTCAAACAAATTCCAGACAAGCCAAACA
CAGTGGTCTGCCTTGAAAATGACCAATGGTCTAACTACGAAACTTTCTGTAATAAAACCTGTAG
TGCTCCACTGAGACTGAATTATGCATCCCTCAAAAAGGAGTATCGTAACATGAATTTTTTCCCA
ATTGGCACCACTGTGGAATTTGAGTGTCGGCCAGGATTTCAAAAAGTAACTTCACGCACAGGAA
AATCAACTTGCCTTGAGGAATTAGTATGGTCTCCAGTTGTTGAATTTTGTAAAAAAAGAGCATG
CCCTAATCCTAGAGAACTGAAAAATGGTCACATCAACATACCAACTGACATATTATTCGGATCA
GAAATAATCTTCTCATGCGACAAAGGGTACAAGCTGGTCGGTGTAACTTCTACATTCTGTTCTA
TTACGGGGAATGCTGTGGACTGGGATGACGTATTTCCAGTGTGCACAACAATTTTTTGTCCAGA
CCCACCAAAAATCAATAATGGAAGAATTCGAGAGGAAAGCGACTCCTACGCATATAGACAGTCG
GTGACCTATTCCTGTGACCAAGGCTTCATTCTGGTTGGAAATTCTTCCGTTCATTGTACTCTGA
ACGGTGAAGTAGGAGAATGGAGTAGTGCACCACCCAAGTGCATAGAGAGACACAAGGTCCCAAC
TAAGACCCCACCAGAAGTTGATATTCCAAGTACAATGCCTCATGAATCCACCTTAATTAATTTT
CCAAGTACAAGAGCCCCACTGTCTCATAAACCCACTACAGTTAAAGTTCCAGCAACACAGCATG
TACCTGTTTCCAAGACAACGGTACGTCATCCAACGAGAACATCTAAAGACAGAGGAGAGTCTAA
TTCAGGTGGTGACCATTTTATATATGGTAAGTTTGACCCACAGGGAGTTAAAAGAAATTGCCAT
CACTGTGGGAGACATAGTCCATATTTCTGGAAGAGAATCTTCTCTTATAACTGCCTGAGAAAAA
CTATCAAAATGCAGTGCCTATGGGTGCCTAAGGGCAGATGGGTAAAGCCTTTTAATCGGCTGGT
TTTTTGGACACCGTTAGGCATCCAGCATGGTCCTTCATATCCCCAACAGTGCTCCTGCTCTAAG
GCAGTCTTAGGACAGCTTCGGGTCATCTGGCCAATCAGTCAGGTAGCACTGAGTGCCCGCTGTG
TCAGTGTGTCATTTTAGTGACAGAAGAAACCCAGGAACAACAGTCAATACAGTTCTTATCCAAA
GAGCATAGTTAACGCCATCTCCAACCATTTTTAGGTCTCTGTCATAGGCCAAACGTGACCAAGA
GCCCCACTTTTCATTATATCTTTCCTTCATCTCTAGTAAAGCTTTTAAGCAGAGTTCTTTTAGA
ATATATTCTCTACATGCTAATATAGTCGGCGAAGGTACAAAACTGTCTCTGTGTTGTGATTCCT
TTTAGCATTTGGTCAGTATTTTTTCTTTGTACATTATACTTACTGTTACTTATTAATAAGGTCC
ACAAATCCCTGAACGAAATGGTAAGGGGCATTGTTAAGTGGGAAAATAGCCAAGTAGTGTACCA
AAGTCATGGGCGACTGTAAATACCCTTTCATGAAAAGATGTTTGTTTTAAAAAAATTTGTACTC
AACAGTGATACCCCCATTTTCATTCATGAAATGTATTAGCTAAGGGACACGCCCTGAAAACAGG
TACTCAGTTTCTACTGTTACCCTTACTGGTATTTGTCTCTCTCTTAGTTTATGTTTAAGCCAAA
GATTTCCTCAGAGGTAGCCCAGCAGGGGCAATTGCTTTTGTACATCTTCTATTTTAAATAGAAA
TAAATATGTTCTAAGCTCATGAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_006249719 ⟹ XP_006249781

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	13	41,858,921 - 41,885,861 (-)	NCBI
Rnor_6.0	13	47,127,609 - 47,153,546 (-)	NCBI
Rnor_5.0	13	52,177,543 - 52,206,137 (-)	NCBI

Sequence:

show sequence

CCCCGCCCCTCCGCAGCCATTCAATTAACCCTGGCTCAAAACAGCTCCAGCCGCAGCCGGGCAC
CGTCTCTTCTACCTGGGGCTATGATCCGCACGCGGGCGCCGGGGACTCGGGCACCGCCGCCGCC
GCCGCTGCTGCTGTCGCTGTCGCTGCTGCTGCTGCTGCTGTCCCCGACTGTAAGCGGAGACTGC
GGCCCACCTCCAGACATTCCTAATGCCACGCCAAACTCGGGTAAACACACCAAGTTTGCCCACC
AAAGCCAAGTGACATATTCGTGTAATAAGGGCTTCAAACAAATTCCAGACAAGCCAAACACAGT
GGTCTGCCTTGAAAATGACCAATGGTCTAACTACGAAACTTTCTGTAATAAAACCTGTAGTGCT
CCACTGAGACTGAATTATGCATCCCTCAAAAAGGAGTATCGTAACATGAATTTTTTCCCAATTG
GCACCACTGTGGAATTTGAGTGTCGGCCAGGATTTCAAAAAGTAACTTCACGCACAGGAAAATC
AACTTGCCTTGAGGAATTAGTATGGTCTCCAGTTGTTGAATTTTGTAAAAAAAGAGCATGCCCT
AATCCTAGAGAACTGAAAAATGGTCACATCAACATACCAACTGACATATTATTCGGATCAGAAA
TAATCTTCTCATGCGACAAAGGGTACAAGCTGGTCGGTGTAACTTCTACATTCTGTTCTATTAC
GGGGAATGCTGTGGACTGGGATGACGTATTTCCAGTGTGCACAACAATTTTTTGTCCAGACCCA
CCAAAAATCAATAATGGAAGAATTCGAGAGGAAAGCGACTCCTACGCATATAGACAGTCGGTGA
CCTATTCCTGTGACCAAGGCTTCATTCTGGTTGGAAATTCTTCCGTTCATTGTACTCTGAACGG
TGAAGTAGGAGAATGGAGTAGTGCACCACCCAAGTGCATAGAGAGACACAAGGTCCCAACTAAG
ACCCCACCAGAAGTTGATATTCCAAGTACAATGCCTCATGAATCCACCTTAATTAATTTTCCAA
GTACAAGAGCCCCACTGTCTCATAAACCCACTACAGTTAAAGTTCCAGCAACACAGCATGTACC
TGTTTCCAAGACAACGGTACGTCATCCAACGAGAACATCTAAAGACAGAGGAGAGTCTAATTCA
GGTGGTGACCATTTTATATATGGACATACATGTTTAATAACCATGACAATTTTGCATGTGATGC
TCTTACTCACTGGCTAGTTGACGTAGCCAACGAAGAGTTAAGAAGAAAGTATATACAACCACTG
AGAATACTTCTAGTTTGTTAGAATGTCCAGGAAGAATGGATACAATAAATTTAATAGTGTTGTT
GGTTCTGTATGCTGTCATCGTCTTGAAGGTGTGCTAGAAATGATAACAAAGCAAGAAGAAAGGA
GGTTGTCTGGAATGGTCTTTTCAATGCATATAAGTCTCTTGAAAATATTTCAAAACTAGACAAA
TTCACAA

hide sequence

RefSeq Acc Id:

XM_006249723 ⟹ XP_006249785

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	13	41,857,242 - 41,885,945 (-)	NCBI
Rnor_6.0	13	47,125,156 - 47,153,557 (-)	NCBI
Rnor_5.0	13	52,177,543 - 52,206,137 (-)	NCBI

Sequence:

show sequence

CGAGAGCCCCGCCCCGCCCCTCCGCAGCCATTCAATTAACCCTGGCTCAAAACAGCTCCAGCCG
CAGCCGGGCACCGTCTCTTCTACCTGGGGCTATGATCCGCACGCGGGCGCCGGGGACTCGGGCA
CCGCCGCCGCCGCCGCTGCTGCTGTCGCTGTCGCTGCTGCTGCTGCTGCTGTCCCCGACTGTAA
GCGGAGACTGCGGCCCACCTCCAGACATTCCTAATGCCACGCCAAACTCGGGTAAACACACCAA
GTTTGCCCACCAAAGCCAAGTGACATATTCGTGTAATAAGGGCTTCAAACAAATTCCAGACAAG
CCAAACACAGTGGTCTGCCTTGAAAATGACCAATGGTCTAACTACGAAACTTTCTGTAATAAAA
CCTGTAGTGCTCCACTGAGACTGAATTATGCATCCCTCAAAAAGGAGTATCGTAACATGAATTT
TTTCCCAATTGGCACCACTGTGGAATTTGAGTGTCGGCCAGGATTTCAAAAAGTAACTTCACGC
ACAGGAAAATCAACTTGCCTTGAGGAATTAGTATGGTCTCCAGTTGTTGAATTTTGTAAAAAAA
GAGCATGCCCTAATCCTAGAGAACTGAAAAATGGTCACATCAACATACCAACTGACATATTATT
CGGATCAGAAATAATCTTCTCATGCGACAAAGGGTACAAGCTGGTCGGTGTAACTTCTACATTC
TGTTCTATTACGGGGAATGCTGTGGACTGGGATGACGTATTTCCAGTGTGCACAACAATTTTTT
GTCCAGACCCACCAAAAATCAATAATGGAAGAATTCGAGAGGAAAGCGACTCCTACGCATATAG
ACAGTCGGTGACCTATTCCTGTGACCAAGGCTTCATTCTGGTTGGAAATTCTTCCGTTCATTGT
ACTCTGAACGGTGAAGTAGGAGAATGGAGTAGTGCACCACCCAAGTGCATAGAGAGACACAAGG
TCCCAACTAAGACCCCACCAGAAGTTGATATTCCAACTACAGAGATCCCACCAACACCCCAGAA
AACCAACACAGCAGATGTCCCATCTACAGAGAGCCCACCAACACCTCAGAAAGCCAACACAGCA
GATGTCCCAGCTACAGAGATCCCACCAACAACGGTACGTCATCCAACGAGAACATCTAAAGACA
GAGGAGAGTCTAATTCAGGTGGTGACCATTTTATATATGGATTTGTTGCTGTTATTGTAACGAT
TGATAGCATAATTCTAATCAAAACTCTTTGGTGGACCATTTTAAGTTCAAACAGAAGCTCTGAC
TTGCAAGGAAAGAAGAAGAGGGAGAATGTCCCAGAGTAAGAAGAGAGCAAGAGTCCACACCATC
TTTTCAAGCTGTTTGGGTGTCTCCTGTGAATTAGATGACGGCTGCCCACATTGTGAGGTTGATC
TTTATTTACACTCCTGATTCCAATG

hide sequence

RefSeq Acc Id:

XM_008769498 ⟹ XP_008767720

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	13	41,858,921 - 41,885,907 (-)	NCBI
Rnor_6.0	13	47,127,609 - 47,153,547 (-)	NCBI

Sequence:

show sequence

GCCCCGCCCCTCCGCAGCCATTCAATTAACCCTGGCTCAAAACAGCTCCAGCCGCAGCCGGGCA
CCGTCTCTTCTACCTGGGGCTATGATCCGCACGCGGGCGCCGGGGACTCGGGCACCGCCGCCGC
CGCCGCTGCTGCTGTCGCTGTCGCTGCTGCTGCTGCTGCTGTCCCCGACTGTAAGCGGAGACTG
CGGCCCACCTCCAGACATTCCTAATGCCACGCCAAACTCGGGTAAACACACCAAGTTTGCCCAC
CAAAGCCAAGTGACATATTCGTGTAATAAGGGCTTCAAACAAATTCCAGACAAGCCAAACACAG
TGGTCTGCCTTGAAAATGACCAATGGTCTAACTACGAAACTTTCTGTAATAAAACCTGTAGTGC
TCCACTGAGACTGAATTATGCATCCCTCAAAAAGGAGTATCGTAACATGAATTTTTTCCCAATT
GGCACCACTGTGGAATTTGAGTGTCGGCCAGGATTTCAAAAAGTAACTTCACGCACAGGAAAAT
CAACTTGCCTTGAGGAATTAGTATGGTCTCCAGTTGTTGAATTTTGTAAAAAAAGAGCATGCCC
TAATCCTAGAGAACTGAAAAATGGTCACATCAACATACCAACTGACATATTATTCGGATCAGAA
ATAATCTTCTCATGCGACAAAGGGTACAAGCTGGTCGGTGTAACTTCTACATTCTGTTCTATTA
CGGGGAATGCTGTGGACTGGGATGACGTATTTCCAGTGTGCACAACAATTTTTTGTCCAGACCC
ACCAAAAATCAATAATGGAAGAATTCGAGAGGAAAGCGACTCCTACGCATATAGACAGTCGGTG
ACCTATTCCTGTGACCAAGGCTTCATTCTGGTTGGAAATTCTTCCGTTCATTGTACTCTGAACG
GTGAAGTAGGAGAATGGAGTAGTGCACCACCCAAGTGCATAGAGAGACACAAGGTCCCAACTAA
GACCCCACCAGAACATGGTTCATCTACAGAAATCCCACCAACACCTCAGAACGCCAACACAGCA
GATGTCCCATCTACAGAGATCCCACCAACACCTCAGAAAACCAACACAGCAAATCATATTACAG
CAACACAGCATGTACCTGTTTCCAAGACAACGGTACGTCATCCAACGAGAACATCTAAAGACAG
AGGAGAGTCTAATTCAGGTGGTGACCATTTTATATATGGACATACATGTTTAATAACCATGACA
ATTTTGCATGTGATGCTCTTACTCACTGGCTAGTTGACGTAGCCAACGAAGAGTTAAGAAGAAA
GTATATACAACCACTGAGAATACTTCTAGTTTGTTAGAATGTCCAGGAAGAATGGATACAATAA
ATTTAATAGTGTTGTTGGTTCTGTATGCTGTCATCGTCTTGAAGGTGTGCTAGAAATGATAACA
AAGCAAGAAGAAAGGAGGTTGTCTGGAATGGTCTTTTCAATGCATATAAGTCTCTTGAAAATAT
TTCAAAACTAGACAAATTCACAA

hide sequence

RefSeq Acc Id:

XM_017598923 ⟹ XP_017454412

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	13	41,857,281 - 41,885,863 (-)	NCBI
Rnor_6.0	13	47,125,176 - 47,153,546 (-)	NCBI

Sequence:

show sequence

CCCCGCCCCTCCGCAGCCATTCAATTAACCCTGGCTCAAAACAGCTCCAGCCGCAGCCGGGCAC
CGTCTCTTCTACCTGGGGCTATGATCCGCACGCGGGCGCCGGGGACTCGGGCACCGCCGCCGCC
GCCGCTGCTGCTGTCGCTGTCGCTGCTGCTGCTGCTGCTGTCCCCGACTGTAAGCGGAGACTGC
GGCCCACCTCCAGACATTCCTAATGCCACGCCAAACTCGGGTAAACACACCAAGTTTGCCCACC
AAAGCCAAGTGACATATTCGTGTAATAAGGGCTTCAAACAAATTCCAGACAAGCCAAACACAGT
GGTCTGCCTTGAAAATGACCAATGGTCTAACTACGAAACTTTCTGTAATAAAACCTGTAGTGCT
CCACTGAGACTGAATTATGCATCCCTCAAAAAGGAGTATCGTAACATGAATTTTTTCCCAATTG
GCACCACTGTGGAATTTGAGTGTCGGCCAGGATTTCAAAAAGTAACTTCACGCACAGGAAAATC
AACTTGCCTTGAGGAATTAGTATGGTCTCCAGTTGTTGAATTTTGTAAAAAAAGAGCATGCCCT
AATCCTAGAGAACTGAAAAATGGTCACATCAACATACCAACTGACATATTATTCGGATCAGAAA
TAATCTTCTCATGCGACAAAGGGTACAAGCTGGTCGGTGTAACTTCTACATTCTGTTCTATTAC
GGGGAATGCTGTGGACTGGGATGACGTATTTCCAGTGTGCACAACAATTTTTTGTCCAGACCCA
CCAAAAATCAATAATGGAAGAATTCGAGAGGAAAGCGACTCCTACGCATATAGACAGTCGGTGA
CCTATTCCTGTGACCAAGGCTTCATTCTGGTTGGAAATTCTTCCGTTCATTGTACTCTGAACGG
TGAAGTAGGAGAATGGAGTAGTGCACCACCCAAGTGCATAGAGAGACACAAGGTCCCAACTAAG
ACCCCACCAGAAGTTGATATTCCAAGTACAATGCCTCATGAATCCACCTTAATTAATTTTCCAA
GTACAAGAGCCCCACTGTCTCATAAACCCACTACAGTTAAAGTTCCAGGTACAAGAGTCAAACC
AACGTCTCACAAGCCCACTGAAGTTAAAGTTCCAGCAACACAGCATGTACCTGTTTCCAAGACA
ACGGTACGTCATCCAACGAGAACATCTAAAGACAGAGGAGAGTCTAATTCAGGTGGTGACCATT
TTATATATGGATTTGTTGCTGTTATTGTAACGATTGATAGCATAATTCTAATCAAAACTCTTTG
GTGGACCATTTTAAGTTCAAACAGAAGCTCTGACTTGCAAGGAAAGAAGAAGAGGGAGAATGTC
CCAGAGTAAGAAGAGAGCAAGAGTCCACACCATCTTTTCAAGCTGTTTGGGTGTCTCCTGTGAA
TTAGATGACGGCTGCCCACATTGTGAGGTTGATCTTTAT

hide sequence

RefSeq Acc Id:

XM_017598924 ⟹ XP_017454413

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	13	41,857,242 - 41,885,966 (-)	NCBI
Rnor_6.0	13	47,125,158 - 47,153,556 (-)	NCBI

Sequence:

show sequence

GAGAGCCCCGCCCCGCCCCTCCGCAGCCATTCAATTAACCCTGGCTCAAAACAGCTCCAGCCGC
AGCCGGGCACCGTCTCTTCTACCTGGGGCTATGATCCGCACGCGGGCGCCGGGGACTCGGGCAC
CGCCGCCGCCGCCGCTGCTGCTGTCGCTGTCGCTGCTGCTGCTGCTGCTGTCCCCGACTGTAAG
CGGAGACTGCGGCCCACCTCCAGACATTCCTAATGCCACGCCAAACTCGGGTAAACACACCAAG
TTTGCCCACCAAAGCCAAGTGACATATTCGTGTAATAAGGGCTTCAAACAAATTCCAGACAAGC
CAAACACAGTGGTCTGCCTTGAAAATGACCAATGGTCTAACTACGAAACTTTCTGTAATAAAAC
CTGTAGTGCTCCACTGAGACTGAATTATGCATCCCTCAAAAAGGAGTATCGTAACATGAATTTT
TTCCCAATTGGCACCACTGTGGAATTTGAGTGTCGGCCAGGATTTCAAAAAGTAACTTCACGCA
CAGGAAAATCAACTTGCCTTGAGGAATTAGTATGGTCTCCAGTTGTTGAATTTTGTAAAAAAAG
AGCATGCCCTAATCCTAGAGAACTGAAAAATGGTCACATCAACATACCAACTGACATATTATTC
GGATCAGAAATAATCTTCTCATGCGACAAAGGGTACAAGCTGGTCGGTGTAACTTCTACATTCT
GTTCTATTACGGGGAATGCTGTGGACTGGGATGACGTATTTCCAGTGTGCACAACAATTTTTTG
TCCAGACCCACCAAAAATCAATAATGGAAGAATTCGAGAGGAAAGCGACTCCTACGCATATAGA
CAGTCGGTGACCTATTCCTGTGACCAAGGCTTCATTCTGGTTGGAAATTCTTCCGTTCATTGTA
CTCTGAACGGTGAAGTAGGAGAATGGAGTAGTGCACCACCCAAGTGCATAGAGAGACACAAGGT
CCCAACTAAGACCCCACCAGAACATGGTTCATCTACAGAAATCCCACCAACACCTCAGAACGCC
AACACAGCAGATGTCCCATCTACAGAGATCCCACCAACACCTCAGAAAACCAACACAGCAAATC
ATATTACAGCAACACAGCATGTACCTGTTTCCAAGACAACGGTACGTCATCCAACGAGAACATC
TAAAGACAGAGGAGAGTCTAATTCAGGTGGTGACCATTTTATATATGGATTTGTTGCTGTTATT
GTAACGATTGATAGCATAATTCTAATCAAAACTCTTTGGTGGACCATTTTAAGTTCAAACAGAA
GCTCTGACTTGCAAGGAAAGAAGAAGAGGGAGAATGTCCCAGAGTAAGAAGAGAGCAAGAGTCC
ACACCATCTTTTCAAGCTGTTTGGGTGTCTCCTGTGAATTAGATGACGGCTGCCCACATTGTGA
GGTTGATCTTTATTTACACTCCTGATTCCAA

hide sequence

RefSeq Acc Id:

XM_039091062 ⟹ XP_038946990

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	13	41,857,268 - 41,885,872 (-)	NCBI

RefSeq Acc Id:

XM_039091063 ⟹ XP_038946991

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	13	41,857,289 - 41,885,571 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_071605	(Get FASTA)	NCBI Sequence Viewer
	XP_006249779	(Get FASTA)	NCBI Sequence Viewer
	XP_006249781	(Get FASTA)	NCBI Sequence Viewer
	XP_006249785	(Get FASTA)	NCBI Sequence Viewer
	XP_008767720	(Get FASTA)	NCBI Sequence Viewer
	XP_017454412	(Get FASTA)	NCBI Sequence Viewer
	XP_017454413	(Get FASTA)	NCBI Sequence Viewer
	XP_038946990	(Get FASTA)	NCBI Sequence Viewer
	XP_038946991	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAC77438	(Get FASTA)	NCBI Sequence Viewer
	AAC77439	(Get FASTA)	NCBI Sequence Viewer
	AAH61869	(Get FASTA)	NCBI Sequence Viewer
	BAA88989	(Get FASTA)	NCBI Sequence Viewer
	BAA88990	(Get FASTA)	NCBI Sequence Viewer
	BAA88991	(Get FASTA)	NCBI Sequence Viewer
	BAA88992	(Get FASTA)	NCBI Sequence Viewer
	BAA88993	(Get FASTA)	NCBI Sequence Viewer
	BAA88994	(Get FASTA)	NCBI Sequence Viewer
	BAA92770	(Get FASTA)	NCBI Sequence Viewer
	BAA92771	(Get FASTA)	NCBI Sequence Viewer
	BAA92772	(Get FASTA)	NCBI Sequence Viewer
	BAF94240	(Get FASTA)	NCBI Sequence Viewer
	BAF94260	(Get FASTA)	NCBI Sequence Viewer
	EDM09864	(Get FASTA)	NCBI Sequence Viewer
	EDM09865	(Get FASTA)	NCBI Sequence Viewer
	EDM09866	(Get FASTA)	NCBI Sequence Viewer
	EDM09867	(Get FASTA)	NCBI Sequence Viewer
	EDM09868	(Get FASTA)	NCBI Sequence Viewer
	EDM09869	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:	NP_071605 ⟸ NM_022269
- Peptide Label:	precursor
- UniProtKB:	Q9Z0M0 (UniProtKB/TrEMBL)
- Sequence:	show sequence MIRTRAPGTRAPPPPPLLLSLSLLLLLLSPTVSGDCGPPPDIPNATPNSGKHTKFAHQSQVTYS CNKGFKQIPDKPNTVVCLENDQWSNYETFCNKTCSAPLRLNYASLKKEYRNMNFFPIGTTVEFE CRPGFQKVTSRTGKSTCLEELVWSPVVEFCKKRACPNPRELKNGHINIPTDILFGSEIIFSCDK GYKLVGVTSTFCSITGNAVDWDDVFPVCTTIFCPDPPKINNGRIREESDSYAYRQSVTYSCDQG FILVGNSSVHCTLNGEVGEWSSAPPKCIERHKVPTKTPPEVDIPSTMPHESTLINFPSTRAPLS HKPTTVKVPGTRVKPTSHKPTEVKVPATQHVPVSKTTVRHPTRTSKDRGESNSGGDHFIYGHTC LITMTILHVMLLLTG hide sequence

RefSeq Acc Id:

XP_006249785 ⟸ XM_006249723

- Peptide Label:

isoform X6

- Sequence:

show sequence

MIRTRAPGTRAPPPPPLLLSLSLLLLLLSPTVSGDCGPPPDIPNATPNSGKHTKFAHQSQVTYS
CNKGFKQIPDKPNTVVCLENDQWSNYETFCNKTCSAPLRLNYASLKKEYRNMNFFPIGTTVEFE
CRPGFQKVTSRTGKSTCLEELVWSPVVEFCKKRACPNPRELKNGHINIPTDILFGSEIIFSCDK
GYKLVGVTSTFCSITGNAVDWDDVFPVCTTIFCPDPPKINNGRIREESDSYAYRQSVTYSCDQG
FILVGNSSVHCTLNGEVGEWSSAPPKCIERHKVPTKTPPEVDIPTTEIPPTPQKTNTADVPSTE
SPPTPQKANTADVPATEIPPTTVRHPTRTSKDRGESNSGGDHFIYGFVAVIVTIDSIILIKTLW
WTILSSNRSSDLQGKKKRENVPE

hide sequence

RefSeq Acc Id:	XP_006249781 ⟸ XM_006249719
- Peptide Label:	isoform X4
- UniProtKB:	A0A0G2QC50 (UniProtKB/TrEMBL)
- Sequence:	show sequence MIRTRAPGTRAPPPPPLLLSLSLLLLLLSPTVSGDCGPPPDIPNATPNSGKHTKFAHQSQVTYS CNKGFKQIPDKPNTVVCLENDQWSNYETFCNKTCSAPLRLNYASLKKEYRNMNFFPIGTTVEFE CRPGFQKVTSRTGKSTCLEELVWSPVVEFCKKRACPNPRELKNGHINIPTDILFGSEIIFSCDK GYKLVGVTSTFCSITGNAVDWDDVFPVCTTIFCPDPPKINNGRIREESDSYAYRQSVTYSCDQG FILVGNSSVHCTLNGEVGEWSSAPPKCIERHKVPTKTPPEVDIPSTMPHESTLINFPSTRAPLS HKPTTVKVPATQHVPVSKTTVRHPTRTSKDRGESNSGGDHFIYGHTCLITMTILHVMLLLTG hide sequence

RefSeq Acc Id:	XP_006249779 ⟸ XM_006249717
- Peptide Label:	isoform X1
- UniProtKB:	Q9Z0L9 (UniProtKB/TrEMBL)
- Sequence:	show sequence MIRTRAPGTRAPPPPPLLLSLSLLLLLLSPTVSGDCGPPPDIPNATPNSGKHTKFAHQSQVTYS CNKGFKQIPDKPNTVVCLENDQWSNYETFCNKTCSAPLRLNYASLKKEYRNMNFFPIGTTVEFE CRPGFQKVTSRTGKSTCLEELVWSPVVEFCKKRACPNPRELKNGHINIPTDILFGSEIIFSCDK GYKLVGVTSTFCSITGNAVDWDDVFPVCTTIFCPDPPKINNGRIREESDSYAYRQSVTYSCDQG FILVGNSSVHCTLNGEVGEWSSAPPKCIERHKVPTKTPPEVDIPSTMPHESTLINFPSTRAPLS HKPTTVKVPATQHVPVSKTTVRHPTRTSKDRGESNSGGDHFIYGKFDPQGVKRNCHHCGRHSPY FWKRIFSYNCLRKTIKMQCLWVPKGRWVKPFNRLVFWTPLGIQHGPSYPQQCSCSKAVLGQLRV IWPISQVALSARCVSVSF hide sequence

RefSeq Acc Id:

XP_008767720 ⟸ XM_008769498

- Peptide Label:

isoform X8

- Sequence:

show sequence

MIRTRAPGTRAPPPPPLLLSLSLLLLLLSPTVSGDCGPPPDIPNATPNSGKHTKFAHQSQVTYS
CNKGFKQIPDKPNTVVCLENDQWSNYETFCNKTCSAPLRLNYASLKKEYRNMNFFPIGTTVEFE
CRPGFQKVTSRTGKSTCLEELVWSPVVEFCKKRACPNPRELKNGHINIPTDILFGSEIIFSCDK
GYKLVGVTSTFCSITGNAVDWDDVFPVCTTIFCPDPPKINNGRIREESDSYAYRQSVTYSCDQG
FILVGNSSVHCTLNGEVGEWSSAPPKCIERHKVPTKTPPEHGSSTEIPPTPQNANTADVPSTEI
PPTPQKTNTANHITATQHVPVSKTTVRHPTRTSKDRGESNSGGDHFIYGHTCLITMTILHVMLL
LTG

hide sequence

RefSeq Acc Id:

XP_017454413 ⟸ XM_017598924

- Peptide Label:

isoform X7

- Sequence:

show sequence

MIRTRAPGTRAPPPPPLLLSLSLLLLLLSPTVSGDCGPPPDIPNATPNSGKHTKFAHQSQVTYS
CNKGFKQIPDKPNTVVCLENDQWSNYETFCNKTCSAPLRLNYASLKKEYRNMNFFPIGTTVEFE
CRPGFQKVTSRTGKSTCLEELVWSPVVEFCKKRACPNPRELKNGHINIPTDILFGSEIIFSCDK
GYKLVGVTSTFCSITGNAVDWDDVFPVCTTIFCPDPPKINNGRIREESDSYAYRQSVTYSCDQG
FILVGNSSVHCTLNGEVGEWSSAPPKCIERHKVPTKTPPEHGSSTEIPPTPQNANTADVPSTEI
PPTPQKTNTANHITATQHVPVSKTTVRHPTRTSKDRGESNSGGDHFIYGFVAVIVTIDSIILIK
TLWWTILSSNRSSDLQGKKKRENVPE

hide sequence

RefSeq Acc Id:

XP_017454412 ⟸ XM_017598923

- Peptide Label:

isoform X2

- Sequence:

show sequence

MIRTRAPGTRAPPPPPLLLSLSLLLLLLSPTVSGDCGPPPDIPNATPNSGKHTKFAHQSQVTYS
CNKGFKQIPDKPNTVVCLENDQWSNYETFCNKTCSAPLRLNYASLKKEYRNMNFFPIGTTVEFE
CRPGFQKVTSRTGKSTCLEELVWSPVVEFCKKRACPNPRELKNGHINIPTDILFGSEIIFSCDK
GYKLVGVTSTFCSITGNAVDWDDVFPVCTTIFCPDPPKINNGRIREESDSYAYRQSVTYSCDQG
FILVGNSSVHCTLNGEVGEWSSAPPKCIERHKVPTKTPPEVDIPSTMPHESTLINFPSTRAPLS
HKPTTVKVPGTRVKPTSHKPTEVKVPATQHVPVSKTTVRHPTRTSKDRGESNSGGDHFIYGFVA
VIVTIDSIILIKTLWWTILSSNRSSDLQGKKKRENVPE

hide sequence

RefSeq Acc Id:

ENSRNOP00000005284 ⟸ ENSRNOT00000005284

RefSeq Acc Id:	XP_038946990 ⟸ XM_039091062
- Peptide Label:	isoform X3

RefSeq Acc Id:	XP_038946991 ⟸ XM_039091063
- Peptide Label:	isoform X5

Protein Domains

Sushi

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13698783

Promoter ID:

EPDNEW_R9308

Type:

initiation region

Name:

Cd55_1

Description:

CD55 molecule, decay accelerating factor for complement

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	13	47,153,498 - 47,153,558	EPDNEW

Strain Variation

Strain Sequence Variants (Rnor 6.0)

ACI/EurMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

ACI/EurMcwi (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

ACI/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

BBDP/Wor (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

BN/SsN (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Buf/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

COP/CrCrl (MCW & UW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob) University of Wisconsin (Dr. James Shull)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Charles River Laboratories
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)

F344/NCrl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

F344/NRrrc (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

FHH/EurMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

FHH/EurMcwi (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

FHL/EurMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

FHL/EurMcwi (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

GH/OmrMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

GK/Ox (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LE/Stm (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LEW/Crl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LEW/NCrlBR (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LH/MavRrrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LL/MavRrrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

LN/MavRrrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

M520/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

MHS/Gib (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

MNS/Gib (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

MR/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

SBH/Ygl (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	SBH/Ygl sequenced by MCW

SBH/Ygl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SBN/Ygl (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	SBN/Ygl sequenced by MCW

SBN/Ygl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SHR/NHsd (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SHRSP/Gcrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SR/JrHsd (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Harlan Laboratories
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

SR/JrHsd (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SS/Jr (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

SS/JrHsdMcwi (MCW)

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Sequenced By:	Medical College of Wisconsin (Dr. Howard Jacob)
Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA v0.7.7 and GATK v3.2-2
Breeder:	Medical College of Wisconsin
Description:	Provided by the Medical College of Wisconsin (Dr. Howard Jacob)

SS/JrHsdMcwi (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WAG/Rij (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/Gcrc (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

WKY/NCrl (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WKY/NHsd (RGD)

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Platform:	Illumina HiSeq 2000
Secondary Analysis:	BWA mem 0.7.15, GATK v.3.6-0
Description:	Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD

WN/N (MCW)

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Sequenced By:	Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen) Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform:	SOLiD 4 and 5500
Secondary Analysis:	liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder:	National Institutes of Health
Description:	Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Damaging Variants

Assembly: Rnor_5.0

Chromosome	Start Pos	End Pos	Reference Nucleotide	Variant Nucleotide	Variant Type	Strain
13	52205295	52205296	G	A	snv	FHH/EurMcwi (KNAW), FHH/EurMcwi (MCW)

Assembly: Rnor_6.0

Chromosome	Start Pos	End Pos	Reference Nucleotide	Variant Nucleotide	Variant Type	Strain
13	47152701	47152702	G	A	snv	FHH/EurMcwi (RGD), FHH/EurMcwi (MCW)

Assembly: RGSC_v3.4

Chromosome	Start Pos	End Pos	Reference Nucleotide	Variant Nucleotide	Variant Type	Strain
13	43347514	43347515	G	A	snv	FHH/EurMcwi (MDC), FHH/EurMcwi (ICL), FHH/EurMcwi (MCW)

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:620651	AgrOrtholog
Ensembl Genes	ENSRNOG00000003927	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein	ENSRNOP00000005284	ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000005284	UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:5598916	IMAGE-MGC_LOAD
InterPro	Sushi/SCR/CCP_sf	UniProtKB/TrEMBL
	Sushi_SCR_CCP	UniProtKB/TrEMBL
KEGG Report	rno:64036	UniProtKB/TrEMBL
MGC_CLONE	MGC:72267	IMAGE-MGC_LOAD
NCBI Gene	64036	ENTREZGENE
Pfam	Sushi	UniProtKB/TrEMBL
PhenoGen	Cd55	PhenoGen
PROSITE	SUSHI	UniProtKB/TrEMBL
SMART	CCP	UniProtKB/TrEMBL
Superfamily-SCOP	Complement_control_module	UniProtKB/TrEMBL
UniProt	A0A0G2QC50	ENTREZGENE, UniProtKB/TrEMBL
	Q9Z0L9	ENTREZGENE, UniProtKB/TrEMBL
	Q9Z0M0	ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary	G3V6H8	UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2015-02-02	Cd55	CD55 molecule, decay accelerating factor for complement	Cd55	Cd55 molecule	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-09-29	Cd55	Cd55 molecule	Cd55	CD55 antigen	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-02-22	Cd55	CD55 antigen	Daf1	decay accelarating factor 1	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2004-12-14	Daf1	decay accelarating factor 1	Daf	decay-accelarating factor	Symbol and Name updated	1299863	APPROVED
2002-08-07	Daf	decay-accelarating factor			Symbol and Name status set to provisional	70820	PROVISIONAL

RGD Curation Notes

Note Type	Note	Reference
gene_domains	contains four SCR domains and a serine/threonine rich-stretch that is heavily O glycosylated	632506
gene_protein	70-kDa glycosylphosphatidylinositol (GPI)-linked glycoprotein	632506

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

RGD Manual Annotations

Imported Annotations - KEGG (archival)

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

Imported Disease Annotations - OMIM

RGD Manual Annotations

Imported Annotations - KEGG (archival)