Hr Rat 17beta-estradiol multiple interactions ISO RGD:1344984 6480464 EGF protein inhibits the reaction [Estradiol results in increased expression of HR mRNA]; Estradiol affects more ... CTD PMID:24758408|PMID:29389661 Hr Rat 17beta-estradiol increases expression ISO RGD:1344984 6480464 Estradiol results in increased expression of HR mRNA CTD PMID:23019147|PMID:24758408|PMID:31614463 Hr Rat 17beta-hydroxy-17-methylestra-4,9,11-trien-3-one multiple interactions ISO RGD:1344984 6480464 [Metribolone binds to and affects the folding of AR protein] inhibits the reaction [AR protein more ... CTD PMID:28751236 Hr Rat 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:1344984 6480464 Tetrachlorodibenzodioxin results in increased expression of HR mRNA CTD PMID:23152189 Hr Rat 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of HR mRNA CTD PMID:33387578 Hr Rat 3,3',5-triiodo-L-thyronine increases expression ISO RGD:735796 6480464 Triiodothyronine results in increased expression of HR mRNA CTD PMID:25172293 Hr Rat 3,3',5-triiodo-L-thyronine increases expression ISO RGD:1344984 6480464 Triiodothyronine results in increased expression of HR mRNA CTD PMID:26096596 Hr Rat 4,4'-sulfonyldiphenol multiple interactions ISO RGD:1344984 6480464 bisphenol S inhibits the reaction [ESR1 protein binds to HR protein] CTD PMID:29389661 Hr Rat 4,4'-sulfonyldiphenol affects methylation ISO RGD:735796 6480464 bisphenol S affects the methylation of HR gene CTD PMID:31683443 Hr Rat 4,4'-sulfonyldiphenol decreases methylation ISO RGD:735796 6480464 bisphenol S results in decreased methylation of HR exon CTD PMID:33297965 Hr Rat 4-hydroxyphenyl retinamide decreases expression ISO RGD:735796 6480464 Fenretinide results in decreased expression of HR mRNA CTD PMID:28973697 Hr Rat 6-propyl-2-thiouracil decreases expression EXP 6480464 Propylthiouracil results in decreased expression of HR mRNA CTD PMID:24780913|PMID:25825206|PMID:30047161|PMID:30085217 Hr Rat aflatoxin B1 increases methylation ISO RGD:1344984 6480464 Aflatoxin B1 results in increased methylation of HR intron CTD PMID:30157460 Hr Rat Aflatoxin B2 alpha increases methylation ISO RGD:1344984 6480464 aflatoxin B2 results in increased methylation of HR intron CTD PMID:30157460 Hr Rat all-trans-retinoic acid decreases expression ISO RGD:1344984 6480464 Tretinoin results in decreased expression of HR mRNA CTD PMID:23724009|PMID:23830798 Hr Rat amitrole decreases expression EXP 6480464 Amitrole results in decreased expression of HR mRNA CTD PMID:30047161|PMID:34757178 Hr Rat ammonium chloride affects expression EXP 6480464 Ammonium Chloride affects the expression of HR mRNA CTD PMID:16483693 Hr Rat benzo[a]pyrene increases methylation ISO RGD:1344984 6480464 Benzo(a)pyrene results in increased methylation of HR 3' UTR; Benzo(a)pyrene results in increased methylation of more ... CTD PMID:27901495 Hr Rat beta-lapachone decreases expression ISO RGD:1344984 6480464 beta-lapachone results in decreased expression of HR mRNA CTD PMID:38218311 Hr Rat beta-lapachone increases expression ISO RGD:1344984 6480464 beta-lapachone results in increased expression of HR mRNA CTD PMID:38218311 Hr Rat bis(2-ethylhexyl) phthalate decreases expression ISO RGD:735796 6480464 Diethylhexyl Phthalate results in decreased expression of HR mRNA CTD PMID:34319233 Hr Rat bisphenol A multiple interactions EXP 6480464 [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in decreased expression more ... CTD PMID:25607892 Hr Rat bisphenol A increases expression ISO RGD:735796 6480464 bisphenol A results in increased expression of HR mRNA CTD PMID:32156529 Hr Rat bisphenol A decreases methylation ISO RGD:1344984 6480464 bisphenol A results in decreased methylation of HR gene CTD PMID:31601247 Hr Rat bisphenol A affects methylation ISO RGD:735796 6480464 bisphenol A affects the methylation of HR promoter CTD PMID:27334623 Hr Rat bisphenol A multiple interactions ISO RGD:1344984 6480464 [bisphenol A binds to and affects the folding of AR protein] promotes the reaction [AR more ... CTD PMID:28751236|PMID:29389661 Hr Rat bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of HR mRNA CTD PMID:25181051 Hr Rat bisphenol AF multiple interactions ISO RGD:1344984 6480464 [bisphenol AF binds to and affects the folding of AR protein] promotes the reaction [AR more ... CTD PMID:28751236|PMID:29389661 Hr Rat butanal decreases expression ISO RGD:1344984 6480464 butyraldehyde results in decreased expression of HR mRNA CTD PMID:26079696 Hr Rat Butylparaben multiple interactions EXP 6480464 [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in decreased expression more ... CTD PMID:25607892 Hr Rat cadmium dichloride decreases expression ISO RGD:1344984 6480464 Cadmium Chloride results in decreased expression of HR mRNA CTD PMID:38568856 Hr Rat calcitriol multiple interactions ISO RGD:1344984 6480464 HR protein inhibits the reaction [Calcitriol results in increased activity of VDR protein mutant form]; more ... CTD PMID:22466564 Hr Rat calcitriol increases expression ISO RGD:1344984 6480464 Calcitriol results in increased expression of HR mRNA CTD PMID:16002434|PMID:26485663 Hr Rat carbon nanotube decreases expression ISO RGD:735796 6480464 Nanotubes, Carbon analog results in decreased expression of HR mRNA; Nanotubes, Carbon results in decreased more ... CTD PMID:25554681 Hr Rat choline multiple interactions ISO RGD:735796 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression more ... CTD PMID:20938992 Hr Rat chrysene increases expression ISO RGD:735796 6480464 chrysene results in increased expression of HR mRNA CTD PMID:26377693 Hr Rat cisplatin decreases expression ISO RGD:1344984 6480464 Cisplatin results in decreased expression of HR mRNA CTD PMID:27392435 Hr Rat clobetasol decreases expression ISO RGD:735796 6480464 Clobetasol results in decreased expression of HR mRNA CTD PMID:27462272 Hr Rat copper(II) chloride decreases expression ISO RGD:1344984 6480464 cupric chloride results in decreased expression of HR mRNA CTD PMID:38568856 Hr Rat Cuprizon decreases expression EXP 6480464 Cuprizone results in decreased expression of HR mRNA CTD PMID:27523638 Hr Rat DDE decreases expression ISO RGD:1344984 6480464 Dichlorodiphenyl Dichloroethylene results in decreased expression of HR mRNA CTD PMID:38568856 Hr Rat dioxygen multiple interactions EXP 6480464 [Oxygen deficiency co-treated with Blood Glucose deficiency co-treated with Particulate Matter] results in increased expression more ... CTD PMID:33729688 Hr Rat doxorubicin decreases expression ISO RGD:1344984 6480464 Doxorubicin results in decreased expression of HR mRNA CTD PMID:29803840|PMID:30031762 Hr Rat endosulfan decreases expression EXP 6480464 Endosulfan results in decreased expression of HR mRNA CTD PMID:29391264 Hr Rat enzacamene multiple interactions EXP 6480464 [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in decreased expression more ... CTD PMID:25607892 Hr Rat flavonoids decreases expression EXP 6480464 Flavonoids results in decreased expression of HR mRNA CTD PMID:18035473 Hr Rat folic acid multiple interactions ISO RGD:735796 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression more ... CTD PMID:20938992 Hr Rat formaldehyde increases expression ISO RGD:1344984 6480464 Formaldehyde results in increased expression of HR mRNA CTD PMID:28937961 Hr Rat genistein increases expression ISO RGD:1344984 6480464 Genistein results in increased expression of HR mRNA CTD PMID:23019147 Hr Rat gentamycin decreases expression EXP 6480464 Gentamicins results in decreased expression of HR mRNA CTD PMID:33387578 Hr Rat GSK-J4 increases expression ISO RGD:1344984 6480464 GSK-J4 results in increased expression of HR mRNA CTD PMID:29301935 Hr Rat L-methionine multiple interactions ISO RGD:735796 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression more ... CTD PMID:20938992 Hr Rat lead(0) increases expression ISO RGD:1344984 6480464 Lead results in increased expression of HR mRNA CTD PMID:19921347 Hr Rat leflunomide increases expression ISO RGD:1344984 6480464 leflunomide results in increased expression of HR mRNA CTD PMID:28988120 Hr Rat lipopolysaccharide multiple interactions ISO RGD:1344984 6480464 [S-(1,2-dichlorovinyl)cysteine co-treated with Lipopolysaccharides] results in decreased expression of HR mRNA CTD PMID:35811015 Hr Rat lithocholic acid multiple interactions ISO RGD:1344984 6480464 HR protein inhibits the reaction [Lithocholic Acid results in increased activity of VDR protein]; HR more ... CTD PMID:22466564 Hr Rat Mesaconitine increases expression EXP 6480464 mesaconitine results in increased expression of HR protein CTD PMID:37182599 Hr Rat methamphetamine decreases expression EXP 6480464 Methamphetamine results in decreased expression of HR mRNA CTD PMID:19564919 Hr Rat methimazole decreases expression EXP 6480464 Methimazole results in decreased expression of HR mRNA CTD PMID:30047161|PMID:34757178 Hr Rat N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal multiple interactions ISO RGD:735796 6480464 MYBPC3 protein affects the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of HR mRNA] CTD PMID:25566086 Hr Rat N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal decreases expression ISO RGD:735796 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of HR mRNA CTD PMID:25566086 Hr Rat N-ethyl-N-nitrosourea increases mutagenesis ISO RGD:735796 6480464 Ethylnitrosourea results in increased mutagenesis of HR exon; Ethylnitrosourea results in increased mutagenesis of HR more ... CTD PMID:16455232|PMID:16461637|PMID:16724327 Hr Rat niclosamide increases expression ISO RGD:1344984 6480464 Niclosamide results in increased expression of HR mRNA CTD PMID:36318118 Hr Rat okadaic acid increases expression ISO RGD:1344984 6480464 Okadaic Acid results in increased expression of HR mRNA CTD PMID:38832940 Hr Rat ozone multiple interactions ISO RGD:735796 6480464 [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in decreased more ... CTD PMID:34911549 Hr Rat ozone decreases expression ISO RGD:735796 6480464 Ozone results in decreased expression of HR mRNA CTD PMID:33026818 Hr Rat paracetamol increases expression ISO RGD:1344984 6480464 Acetaminophen results in increased expression of HR mRNA CTD PMID:22230336 Hr Rat paracetamol decreases expression EXP 6480464 Acetaminophen results in decreased expression of HR mRNA CTD PMID:33387578 Hr Rat paracetamol decreases expression ISO RGD:1344984 6480464 Acetaminophen results in decreased expression of HR mRNA CTD PMID:26690555 Hr Rat paraquat decreases expression EXP 6480464 Paraquat results in decreased expression of HR mRNA CTD PMID:32680482 Hr Rat paraquat increases expression ISO RGD:735796 6480464 Paraquat results in increased expression of HR mRNA CTD PMID:21463325 Hr Rat pirinixic acid multiple interactions ISO RGD:735796 6480464 [pirinixic acid co-treated with PPARA] results in increased expression of HR mRNA CTD PMID:20813756 Hr Rat pirinixic acid increases expression ISO RGD:735796 6480464 pirinixic acid results in increased expression of HR mRNA CTD PMID:20813756 Hr Rat potassium dichromate increases expression ISO RGD:735796 6480464 Potassium Dichromate results in increased expression of HR mRNA CTD PMID:23608068 Hr Rat resveratrol increases expression ISO RGD:1344984 6480464 resveratrol results in increased expression of HR mRNA CTD PMID:25888808 Hr Rat resveratrol multiple interactions ISO RGD:1344984 6480464 [Plant Extracts co-treated with Resveratrol] results in decreased expression of HR mRNA CTD PMID:23557933 Hr Rat S-(1,2-dichlorovinyl)-L-cysteine decreases expression ISO RGD:1344984 6480464 S-(1,2-dichlorovinyl)cysteine results in decreased expression of HR mRNA CTD PMID:35811015 Hr Rat S-(1,2-dichlorovinyl)-L-cysteine multiple interactions ISO RGD:1344984 6480464 [S-(1,2-dichlorovinyl)cysteine co-treated with Lipopolysaccharides] results in decreased expression of HR mRNA CTD PMID:35811015 Hr Rat sodium arsenite decreases expression ISO RGD:1344984 6480464 sodium arsenite results in decreased expression of HR mRNA CTD PMID:38568856 Hr Rat sodium arsenite increases expression ISO RGD:1344984 6480464 sodium arsenite results in increased expression of HR mRNA CTD PMID:34032870 Hr Rat staurosporine multiple interactions ISO RGD:735796 6480464 HR protein affects the reaction [Staurosporine results in increased activity of CASP3 protein]; TRP53 protein more ... CTD PMID:20886113 Hr Rat staurosporine multiple interactions EXP 6480464 HR protein inhibits the reaction [Staurosporine results in increased activity of CASP3 protein]; HR protein more ... CTD PMID:20886113 Hr Rat staurosporine affects response to substance ISO RGD:735796 6480464 HR protein affects the susceptibility to Staurosporine CTD PMID:20886113 Hr Rat sulforaphane decreases expression ISO RGD:1344984 6480464 sulforaphane results in decreased expression of HR mRNA CTD PMID:31838189 Hr Rat sunitinib decreases expression ISO RGD:1344984 6480464 Sunitinib results in decreased expression of HR mRNA CTD PMID:31533062 Hr Rat tamoxifen increases expression ISO RGD:735796 6480464 Tamoxifen results in increased expression of HR mRNA CTD PMID:25123088 Hr Rat testosterone increases expression ISO RGD:735796 6480464 Testosterone results in increased expression of HR mRNA CTD PMID:20403060 Hr Rat thapsigargin affects response to substance ISO RGD:735796 6480464 HR protein affects the susceptibility to Thapsigargin CTD PMID:20886113 Hr Rat thapsigargin multiple interactions ISO RGD:735796 6480464 HR protein affects the reaction [Thapsigargin results in increased activity of CASP3 protein] CTD PMID:20886113 Hr Rat thyroxine increases expression EXP 6480464 Thyroxine results in increased expression of HR mRNA CTD PMID:29901742 Hr Rat titanium dioxide increases methylation ISO RGD:735796 6480464 titanium dioxide results in increased methylation of HR gene CTD PMID:35295148 Hr Rat trichostatin A multiple interactions ISO RGD:1344984 6480464 trichostatin A inhibits the reaction [HR protein inhibits the reaction [Calcitriol results in increased activity more ... CTD PMID:22466564 Hr Rat trichostatin A decreases expression ISO RGD:1344984 6480464 trichostatin A results in decreased expression of HR mRNA CTD PMID:28542535 Hr Rat trimethyltin multiple interactions ISO RGD:735796 6480464 HR protein affects the reaction [trimethyltin results in increased activity of CASP3 protein] CTD PMID:20886113 Hr Rat trimethyltin affects response to substance ISO RGD:735796 6480464 HR protein affects the susceptibility to trimethyltin CTD PMID:20886113 Hr Rat triptonide increases expression ISO RGD:735796 6480464 triptonide results in increased expression of HR mRNA CTD PMID:33045310 Hr Rat tunicamycin multiple interactions ISO RGD:735796 6480464 TRP53 protein affects the reaction [HR protein affects the reaction [Tunicamycin results in increased activity more ... CTD PMID:20886113 Hr Rat tunicamycin multiple interactions EXP 6480464 HR protein inhibits the reaction [Tunicamycin results in increased activity of CASP3 protein]; HR protein more ... CTD PMID:20886113 Hr Rat urethane decreases expression ISO RGD:1344984 6480464 Urethane results in decreased expression of HR mRNA CTD PMID:28818685 Hr Rat valproic acid increases methylation ISO RGD:1344984 6480464 Valproic Acid results in increased methylation of HR gene CTD PMID:29154799