Rbm14 (RNA binding motif protein 14) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Behavioral & Substance Use Disorder Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Rbm14 (RNA binding motif protein 14) Rattus norvegicus
Analyze
Symbol: Rbm14
Name: RNA binding motif protein 14
RGD ID: 620542
Description: Predicted to enable mRNA binding activity; splicing factor binding activity; and transcription coactivator activity. Predicted to be involved in several processes, including centriole assembly; negative regulation of centriole replication; and regulation of gene expression. Predicted to act upstream of or within apoptotic process; gastrulation; and regulation of response to DNA integrity checkpoint signaling. Predicted to be located in cytoplasm and nucleus. Predicted to be part of transcription regulator complex. Predicted to be active in nuclear speck. Orthologous to several human genes including RBM14 (RNA binding motif protein 14); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; ammonium chloride.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: CoAA; coactivator activator; RNA-binding protein 14
RGD Orthologs
Human
Mouse
Bonobo
Dog
Squirrel
Pig
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81211,476,298 - 211,535,077 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1211,523,972 - 211,535,065 (-)EnsemblGRCr8
mRatBN7.21202,076,940 - 202,105,688 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1202,085,279 - 202,105,380 (-)EnsemblmRatBN7.2
mRatBN7.2 Ensembl1202,078,287 - 202,105,665 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1210,447,704 - 210,458,798 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01217,540,005 - 217,551,099 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01210,231,028 - 210,242,121 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01220,048,740 - 220,067,124 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1220,048,873 - 220,067,124 (-)Ensemblrn6Rnor6.0
Rnor_5.01226,920,879 - 226,931,972 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41207,410,484 - 207,421,760 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1199,635,075 - 199,646,168 (-)NCBICelera
Cytogenetic Map1q43NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,6-dimethoxyphenol  (ISO)
3',5'-cyclic UMP  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (ISO)
5-fluorouracil  (ISO)
acrolein  (ISO)
alpha-pinene  (ISO)
ammonium chloride  (EXP)
amphetamine  (EXP)
atrazine  (ISO)
azoxystrobin  (EXP)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
beta-lapachone  (ISO)
bisphenol A  (EXP,ISO)
Bisphenol B  (ISO)
Brodifacoum  (EXP)
C60 fullerene  (EXP)
cadmium dichloride  (ISO)
caffeine  (ISO)
carbamazepine  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chloropicrin  (ISO)
chlorpyrifos  (EXP,ISO)
choline  (ISO)
cisplatin  (ISO)
clofibrate  (ISO)
cobalt dichloride  (ISO)
cocaine  (EXP)
copper(II) sulfate  (ISO)
coumarin  (ISO)
crocidolite asbestos  (ISO)
cyclosporin A  (ISO)
Dibutyl phosphate  (ISO)
dicrotophos  (ISO)
diuron  (EXP)
elemental selenium  (ISO)
endosulfan  (EXP)
enzyme inhibitor  (ISO)
ethanol  (ISO)
flutamide  (EXP)
folic acid  (ISO)
FR900359  (ISO)
furfural  (ISO)
glyphosate  (EXP)
hydrogen cyanide  (ISO)
imidacloprid  (EXP)
inulin  (ISO)
ivermectin  (ISO)
L-methionine  (ISO)
leflunomide  (ISO)
methyl methanesulfonate  (ISO)
methylparaben  (ISO)
ozone  (ISO)
paracetamol  (EXP,ISO)
pentachlorophenol  (ISO)
perfluorohexanesulfonic acid  (ISO)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
PhIP  (ISO)
potassium cyanide  (ISO)
progesterone  (EXP)
selenium atom  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
sodium chloride  (ISO)
Soman  (EXP)
temozolomide  (ISO)
tetrachloromethane  (ISO)
thiabendazole  (EXP)
thioacetamide  (EXP)
titanium dioxide  (ISO)
Tributyltin oxide  (ISO)
trichloroethene  (EXP)
trimellitic anhydride  (ISO)
tunicamycin  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
vitamin E  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
activation of innate immune response  (IEA,ISO)
apoptotic process  (IEA,ISO)
cap-independent translational initiation  (IEA)
centriole assembly  (IEA,ISO)
circadian regulation of gene expression  (IEA)
circadian regulation of translation  (IEA)
enteroendocrine cell differentiation  (IEA)
entrainment of circadian clock by photoperiod  (IEA)
gastrulation  (IEA,ISO)
gene expression  (IEA)
glucose homeostasis  (IEA)
insulin secretion involved in cellular response to glucose stimulus  (IEA)
IRES-dependent translational initiation of linear mRNA  (IEA)
miRNA-mediated gene silencing by inhibition of translation  (IEA)
mRNA splicing, via spliceosome  (IEA,ISO)
negative regulation of centriole replication  (IEA,ISO)
negative regulation of translation  (IEA)
negative regulation of translation in response to stress  (IEA)
negative regulation of translational initiation  (IEA)
pancreas development  (IEA)
positive regulation of muscle cell differentiation  (IEA)
positive regulation of transcription by RNA polymerase II  (IEA,ISO)
positive regulation of translation  (IEA)
regulation of alternative mRNA splicing, via spliceosome  (IBA,IEA)
regulation of gene expression  (IEA)
regulation of insulin receptor signaling pathway  (IEA)
regulation of nucleocytoplasmic transport  (IEA)
regulation of response to DNA integrity checkpoint signaling  (IEA,ISO)
regulation of translation  (IEA)
response to arsenic-containing substance  (IEA)
transcription initiation-coupled chromatin remodeling  (IEA,ISO)

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Identification and characterization of RRM-containing coactivator activator (CoAA) as TRBP-interacting protein, and its splice variant as a coactivator modulator (CoAM). Iwasaki T, etal., J Biol Chem 2001 Sep 7;276(36):33375-83.
3. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
4. GOA pipeline RGD automated data pipeline
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:15919756   PMID:19585539   PMID:21700703   PMID:22658674   PMID:22681889   PMID:23390484   PMID:24625528   PMID:25385835   PMID:26306672   PMID:28712728  


Genomics

Comparative Map Data
Rbm14
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81211,476,298 - 211,535,077 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1211,523,972 - 211,535,065 (-)EnsemblGRCr8
mRatBN7.21202,076,940 - 202,105,688 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1202,085,279 - 202,105,380 (-)EnsemblmRatBN7.2
mRatBN7.2 Ensembl1202,078,287 - 202,105,665 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1210,447,704 - 210,458,798 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01217,540,005 - 217,551,099 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01210,231,028 - 210,242,121 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01220,048,740 - 220,067,124 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1220,048,873 - 220,067,124 (-)Ensemblrn6Rnor6.0
Rnor_5.01226,920,879 - 226,931,972 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41207,410,484 - 207,421,760 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1199,635,075 - 199,646,168 (-)NCBICelera
Cytogenetic Map1q43NCBI
RBM14
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381166,616,630 - 66,629,934 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1166,616,626 - 66,629,934 (+)Ensemblhg38GRCh38
GRCh371166,384,101 - 66,397,405 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361166,140,673 - 66,151,390 (+)NCBIBuild 36Build 36hg18NCBI36
Build 341166,140,672 - 66,151,387NCBI
Celera1163,709,642 - 63,722,994 (+)NCBICelera
Cytogenetic Map11q13.2NCBI
HuRef1162,712,391 - 62,725,735 (+)NCBIHuRef
CHM1_11166,267,779 - 66,281,131 (+)NCBICHM1_1
T2T-CHM13v2.01166,612,875 - 66,626,179 (+)NCBIT2T-CHM13v2.0
Rbm14
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39194,850,594 - 4,861,662 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl194,850,597 - 4,861,662 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38194,800,566 - 4,811,634 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl194,800,569 - 4,811,634 (-)Ensemblmm10GRCm38
MGSCv37194,800,925 - 4,811,634 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36194,800,925 - 4,811,634 (-)NCBIMGSCv36mm8
Celera194,672,136 - 4,682,851 (-)NCBICelera
Cytogenetic Map19ANCBI
cM Map194.11NCBI
RBM14
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2967,841,448 - 67,853,359 (+)NCBINHGRI_mPanPan1-v2
PanPan1.1 Ensembl1165,298,404 - 65,349,183 (+)EnsemblpanPan2panpan1.1
RBM14
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11850,683,227 - 50,728,512 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1850,705,024 - 50,811,319 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha1849,292,077 - 49,337,317 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.01851,714,151 - 51,759,600 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1851,714,157 - 51,759,574 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11850,816,135 - 50,861,524 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01850,395,831 - 50,441,059 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01851,185,785 - 51,231,034 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
LOC110596870
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244049476,473,886 - 6,541,704 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365992,975,350 - 2,984,060 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365992,968,178 - 2,984,033 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RBM14
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl25,759,098 - 5,800,748 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.125,791,445 - 5,800,784 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1

Variants

.
Variants in Rbm14
104 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:587
Count of miRNA genes:180
Interacting mature miRNAs:204
Transcripts:ENSRNOT00000070945, ENSRNOT00000071020, ENSRNOT00000071077, ENSRNOT00000071121, ENSRNOT00000072373, ENSRNOT00000072523, ENSRNOT00000072586, ENSRNOT00000074289
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1578778Pur4Proteinuria QTL 43.30.003urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)1150700247252085048Rat
1354646Kidm18Kidney mass QTL 185.7kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1151162512256448636Rat
1357335Bw39Body weight QTL 393.3body mass (VT:0001259)body weight (CMO:0000012)1197814409242814409Rat
1578780Cm52Cardiac mass QTL 523.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)181591954219808434Rat
2302375Bw83Body weight QTL 834.870.0002body mass (VT:0001259)body weight (CMO:0000012)1197697768242697768Rat
1354652Kidm20Kidney mass QTL 204.3kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1177227632256448636Rat
2293674Bss39Bone structure and strength QTL 397.10.0001femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)1201554356246554356Rat
2302378Insul11Insulin level QTL 113.25blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)1144267353251128347Rat
1354653Despr9Despair related QTL 90.00019locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)1167909849212909849Rat
2293673Bss27Bone structure and strength QTL 2718.630.0001femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)1171629477216629477Rat
2293677Bss41Bone structure and strength QTL 419.380.0001lumbar vertebra size trait (VT:0010518)lumbar vertebra cross-sectional area (CMO:0001689)1171629477216629477Rat
1302787Stl25Serum triglyceride level QTL 252.70.0073blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)1180359209210702199Rat
1549830Bss1Bone structure and strength QTL 14.8femur strength trait (VT:0010010)femur ultimate force (CMO:0001675)1172609619217609619Rat
7794788Mcs32Mammary carcinoma susceptibility QTL 322.61mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)1115540693238914717Rat
70163Bw20Body weight QTL 205.1body mass (VT:0001259)body weight (CMO:0000012)1174133260219133260Rat
1578763Kidm29Kidney mass QTL 293.30.0001kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)1179567751260522016Rat
1600395Niddm69Non-insulin dependent diabetes mellitus QTL 694.140.0002blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)1195804352257091168Rat
1354624Cm35Cardiac mass QTL355.7heart left ventricle mass (VT:0007031)calculated heart weight (CMO:0000073)1177227632256448636Rat
1600396Niddm68Non-insulin dependent diabetes mellitus QTL 684.970.0003blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1195804352257091168Rat
1558658Bw59Body weight QTL 593.50.0003body mass (VT:0001259)body weight (CMO:0000012)1178784622223784622Rat
631838Niddm36Non-insulin dependent diabetes mellitus QTL 360.01insulin secretion trait (VT:0003564)calculated pancreatic islet insulin release measurement (CMO:0001217)1184550676229550676Rat
1549837Hcar15Hepatocarcinoma resistance QTL 150.05liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)1153136852260522016Rat
2293689Bss47Bone structure and strength QTL 477.250.0001lumbar vertebra size trait (VT:0010518)lumbar vertebra trabecular cross-sectional area (CMO:0001692)1171629477216629477Rat
152025235Bw194Body weight QTL 1944.86body mass (VT:0001259)1123556856242907031Rat
1600388Niddm67Non-insulin dependent diabetes mellitus QTL 675.840.000004blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1195804352257091168Rat
2293694Bss38Bone structure and strength QTL 387.050.0001femur strength trait (VT:0010010)femur stiffness (CMO:0001674)1201554356246554356Rat
1598853Memor3Memory QTL 34.5exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)1143506580212458660Rat
61341Bp26Blood pressure QTL 26arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1169537671214537671Rat
1578759Uae30Urinary albumin excretion QTL 303.30.003urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1150700247252085048Rat
2293693Bss22Bone structure and strength QTL 2233.520.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)1171629477216629477Rat
2300161Bmd43Bone mineral density QTL 438.40.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)1171629477216629477Rat
1300145Rf7Renal function QTL 72.96urine creatinine amount (VT:0010540)urine creatinine level (CMO:0000125)1185145134221264292Rat
61347Bp197Blood pressure QTL 1974.2arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)1158633083203633083Rat
8655655Arrd2Age-related retinal degeneration QTL 27.79retinal layer morphology trait (VT:0003727)percentage of study population developing retinopathy during a period of time (CMO:0002453)1183970203243914901Rat
1358898Bp255Blood pressure QTL 2553.6arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1191019702246062233Rat
631214Bw61Body weight QTL613.40.0001intramuscular adipose amount (VT:0010044)intramuscular fat area (CMO:0001162)1173108781218108781Rat
7771612Cm80Cardiac mass QTL 808.4heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)1149448574221264292Rat
731168Bp154Blood pressure QTL 1543.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)194642644214537671Rat
2300175Bmd40Bone mineral density QTL 4015.40.0001femur mineral mass (VT:0010011)bone mineral density (CMO:0001226)1201554356246554356Rat
2300174Bmd42Bone mineral density QTL 428.40.0001lumbar vertebra mineral mass (VT:0010511)bone mineral density (CMO:0001226)1171629477216629477Rat
737828Hcas3Hepatocarcinoma susceptibility QTL 34.9liver integrity trait (VT:0010547)liver tumorous lesion volume to total liver volume ratio (CMO:0001082)1144267353222987745Rat
1354661Bw33Body weight QTL 335.2body mass (VT:0001259)body weight (CMO:0000012)1151162512256448636Rat
1358886Bp260Blood pressure QTL 2603.67arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1151162766225824951Rat
737977Bp160Blood pressure QTL 1600.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1181133855226133855Rat
2293654Bss30Bone structure and strength QTL 3032.650.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)1171629477216629477Rat
2293655Bss36Bone structure and strength QTL 3610.660.0001femur strength trait (VT:0010010)femur ultimate force (CMO:0001675)1201554356246554356Rat
1298084Thym4Thymus enlargement QTL 410.68thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)1197814409242814409Rat
724531Uae5Urinary albumin excretion QTL 54urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)1150700142252085212Rat
2300187Bmd41Bone mineral density QTL 418.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)1171629477216629477Rat
2314011Gluco56Glucose level QTL 56blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)1199773958202166723Rat
8552891Epfw5Epididymal fat weight QTL 54.4epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)1193113876238113876Rat
1359018Hrtrt20Heart rate QTL 203.08heart pumping trait (VT:2000009)heart rate (CMO:0000002)1185356336202902618Rat
1354580Scort1Serum corticosterone level QTL 13.4blood corticosterone amount (VT:0005345)blood corticosterone level (CMO:0001172)1156677124256448636Rat
1358292Cm37Cardiac mass QTL 376.28e-07heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)1196248093241248093Rat
61376Bp42Blood pressure QTL 4223.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1197814409242814409Rat
634313Niddm43Non-insulin dependent diabetes mellitus QTL 43blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1199050459259647894Rat
634312Bp143Blood pressure QTL 14330.0002arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1182623426219932796Rat
1358294Bw37Body weight QTL 3750.000011body mass (VT:0001259)body weight (CMO:0000012)1171310381216310381Rat
724559Pancm1Pancreatic morphology QTL 17.1islet of Langerhans morphology trait (VT:0005215)pancreatic islet damage composite score (CMO:0001156)1181759564214537555Rat
2312420Pur17Proteinuria QTL 177.10.0001urine protein amount (VT:0005160)urine total protein excretion rate (CMO:0000756)1156677124218753816Rat
10059600Bp378Blood pressure QTL 3783.080.05arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1176869060221869060Rat
7421630Bp362Blood pressure QTL 3620.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1118608292241799120Rat
619613Bp77Blood pressure QTL 770.01arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)1164747424209747424Rat
2312564Glom18Glomerulus QTL 182.40.003kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)1185356336231689108Rat
634321Hc1Hypercalciuria QTL 12.91urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)1178810256240830002Rat
2292218Kidm35Kidney mass QTL 35kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)1199368955224569684Rat
724562Rends1Renal damage susceptibility QTL 10.05kidney glomerulus integrity trait (VT:0010546)index of glomerular damage (CMO:0001135)1169537671214537671Rat
1331790Bp201Blood pressure QTL 2013.127arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1198211513225126682Rat
10059587Bw173Body weight QTL 1733.230.025body mass (VT:0001259)body weight (CMO:0000012)1202069611247069611Rat
2292222Bp307Blood pressure QTL 3073.060.0014arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1164310393213533942Rat
2292220Bp306Blood pressure QTL 3063.470.00087arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1164310393243914901Rat
10059590Kidm44Kidney mass QTL 443.420.025kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)1191033875236033875Rat
1641926Teswt2Testicular weight QTL 22.82testis mass (VT:1000644)both testes wet weight (CMO:0000175)1197697768238755659Rat
631658Cm7Cardiac mass QTL 75.320.0001aorta mass (VT:0002845)aorta weight (CMO:0000076)1196248093241248093Rat
1600380Niddm70Non-insulin dependent diabetes mellitus QTL 703.10.0008blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)1176550523221550523Rat
1354610Bw34Body weight QTL 344.1body mass (VT:0001259)body weight (CMO:0000012)1151162512256448636Rat
1582206Kidm33Kidney mass QTL 336.9kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)1188377360224054420Rat
8655855Arrd3Age-related retinal degeneration QTL 33.07lens clarity trait (VT:0001304)cataract incidence/prevalence measurement (CMO:0001585)1183970203243914901Rat
634338Hcar4Hepatocarcinoma resistance QTL 44.6liver integrity trait (VT:0010547)liver tumorous lesion number to liver area ratio (CMO:0001210)1193422268214537671Rat
6903303Scl34Serum cholesterol QTL 342.50.0033blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)1180359209218108781Rat
1600374Mcs17Mammary carcinoma susceptibility QTL 173mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)1197670404242670404Rat
2293083Iddm25Insulin dependent diabetes mellitus QTL 254.18blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1181829673224569684Rat
1354606Bp246Blood pressure QTL 2463.6arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)1102813953218753816Rat
738032Hcas5Hepatocarcinoma susceptibility QTL 53.12liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)1176426412257976495Rat
1358191Ept10Estrogen-induced pituitary tumorigenesis QTL 103.8pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)1192825253243914732Rat
7394701Uae46Urinary albumin excretion QTL 463.60.0056urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1201554356246554356Rat

Markers in Region
RH142163  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21202,095,076 - 202,095,292 (+)MAPPERmRatBN7.2
Rnor_6.01220,056,537 - 220,056,752NCBIRnor6.0
Rnor_5.01226,987,535 - 226,987,750UniSTSRnor5.0
Rnor_5.01226,921,385 - 226,921,600UniSTSRnor5.0
RGSC_v3.41207,410,984 - 207,411,199UniSTSRGSC3.4
Celera1199,635,581 - 199,635,796UniSTS
RH 3.4 Map11555.9UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_133388 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008760067 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039084839 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063272688 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063272714 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063272752 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010057081 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010057136 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010057152 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010057187 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010057218 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010057234 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC126581 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF327567 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473953 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ219324 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000001 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000067093   ⟹   ENSRNOP00000059872
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1211,507,674 - 211,516,891 (-)Ensembl
mRatBN7.2 Ensembl1202,085,279 - 202,087,482 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000071020   ⟹   ENSRNOP00000064114
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1211,506,343 - 211,516,871 (-)Ensembl
mRatBN7.2 Ensembl1202,078,287 - 202,105,654 (-)Ensembl
Rnor_6.0 Ensembl1220,048,873 - 220,067,123 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000072373   ⟹   ENSRNOP00000066778
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1211,523,972 - 211,535,065 (-)Ensembl
mRatBN7.2 Ensembl1202,094,571 - 202,105,665 (-)Ensembl
Rnor_6.0 Ensembl1220,056,031 - 220,067,124 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000087573   ⟹   ENSRNOP00000072133
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1202,085,310 - 202,105,380 (-)Ensembl
RefSeq Acc Id: NM_133388   ⟹   NP_596879
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81211,523,972 - 211,535,065 (-)NCBI
mRatBN7.21202,094,571 - 202,105,665 (-)NCBI
Rnor_6.01220,056,031 - 220,067,124 (-)NCBI
Rnor_5.01226,920,879 - 226,931,972 (-)NCBI
Celera1199,635,075 - 199,646,168 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039084839   ⟹   XP_038940767
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81211,516,879 - 211,535,077 (-)NCBI
mRatBN7.21202,087,280 - 202,105,688 (-)NCBI
RefSeq Acc Id: XM_063272688   ⟹   XP_063128758
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81211,476,298 - 211,516,990 (-)NCBI
RefSeq Acc Id: XM_063272714   ⟹   XP_063128784
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81211,514,680 - 211,515,823 (-)NCBI
RefSeq Acc Id: XM_063272752   ⟹   XP_063128822
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81211,516,877 - 211,535,074 (-)NCBI
RefSeq Acc Id: XR_010057081
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81211,476,298 - 211,515,823 (-)NCBI
RefSeq Acc Id: XR_010057136
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81211,476,298 - 211,515,823 (-)NCBI
RefSeq Acc Id: XR_010057152
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81211,476,298 - 211,515,823 (-)NCBI
RefSeq Acc Id: XR_010057187
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81211,476,298 - 211,515,823 (-)NCBI
RefSeq Acc Id: XR_010057218
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81211,476,298 - 211,515,823 (-)NCBI
RefSeq Acc Id: XR_010057234
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81211,476,298 - 211,515,823 (-)NCBI
RefSeq Acc Id: NP_596879   ⟸   NM_133388
- UniProtKB: M0R9Q1 (UniProtKB/TrEMBL),   A6HYZ2 (UniProtKB/TrEMBL),   A6HYZ3 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000064114   ⟸   ENSRNOT00000071020
Ensembl Acc Id: ENSRNOP00000066778   ⟸   ENSRNOT00000072373
RefSeq Acc Id: XP_038940767   ⟸   XM_039084839
- Peptide Label: isoform X1
- UniProtKB: M0R3R6 (UniProtKB/TrEMBL),   A6HYZ3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063128758   ⟸   XM_063272688
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063128784   ⟸   XM_063272714
- Peptide Label: isoform X3
- UniProtKB: A0A8I6A8X6 (UniProtKB/TrEMBL),   A6HYY8 (UniProtKB/TrEMBL),   A0A8J8YGL2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063128822   ⟸   XM_063272752
- Peptide Label: isoform X4
Ensembl Acc Id: ENSRNOP00000072133   ⟸   ENSRNOT00000087573
Ensembl Acc Id: ENSRNOP00000059872   ⟸   ENSRNOT00000067093
Protein Domains
RRM

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-M0R9Q1-F1-model_v2 AlphaFold M0R9Q1 1-669 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13690631
Promoter ID:EPDNEW_R1155
Type:multiple initiation site
Name:Rbm14_1
Description:RNA binding motif protein 14
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01220,067,109 - 220,067,169EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:620542 AgrOrtholog
BioCyc Gene G2FUF-56736 BioCyc
Ensembl Genes ENSRNOG00000045568 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOG00000050741 Ensembl, UniProtKB/TrEMBL
  ENSRNOG00000061795 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000067093.4 UniProtKB/TrEMBL
  ENSRNOT00000071020.3 UniProtKB/TrEMBL
  ENSRNOT00000072373 ENTREZGENE
  ENSRNOT00000072373.4 UniProtKB/TrEMBL
  ENSRNOT00000087573.2 UniProtKB/TrEMBL
  ENSRNOT00000107410.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.70.330 UniProtKB/TrEMBL
InterPro Euk_RNA-bind_prot UniProtKB/TrEMBL
  Nucleotide-bd_a/b_plait_sf UniProtKB/TrEMBL
  RBD_domain_sf UniProtKB/TrEMBL
  RBM14_RRM1 UniProtKB/TrEMBL
  RBM14_RRM2 UniProtKB/TrEMBL
  RBM4_RRM1 UniProtKB/TrEMBL
  RRM_dom UniProtKB/TrEMBL
  SRSF UniProtKB/TrEMBL
KEGG Report rno:170900 UniProtKB/TrEMBL
NCBI Gene 170900 ENTREZGENE
PANTHER HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN M-RELATED UniProtKB/TrEMBL
  OS02G0815200 PROTEIN UniProtKB/TrEMBL
  SERINE/ARGININE RICH SPLICING FACTOR UniProtKB/TrEMBL
Pfam RRM_1 UniProtKB/TrEMBL
PhenoGen Rbm14 PhenoGen
PROSITE PROKAR_LIPOPROTEIN UniProtKB/TrEMBL
  RRM UniProtKB/TrEMBL
RatGTEx ENSRNOG00000045568 RatGTEx
  ENSRNOG00000050741 RatGTEx
  ENSRNOG00000061795 RatGTEx
SMART RRM UniProtKB/TrEMBL
Superfamily-SCOP SSF54928 UniProtKB/TrEMBL
UniProt A0A8I6A8X6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8J8YGL2 ENTREZGENE, UniProtKB/TrEMBL
  A6HYY8 ENTREZGENE, UniProtKB/TrEMBL
  A6HYZ2 ENTREZGENE, UniProtKB/TrEMBL
  A6HYZ3 ENTREZGENE, UniProtKB/TrEMBL
  D4A1W5_RAT UniProtKB/TrEMBL
  M0R3R6 ENTREZGENE, UniProtKB/TrEMBL
  M0R9Q1 ENTREZGENE, UniProtKB/TrEMBL
  Q5U212_RAT UniProtKB/TrEMBL
UniProt Secondary F7FC23 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2005-01-20 Rbm14  RNA binding motif protein 14      Symbol and Name status set to approved 1299863 APPROVED
2002-08-07 Rbm14  RNA binding motif protein 14      Symbol and Name status set to provisional 70820 PROVISIONAL