Cbfb (core-binding factor subunit beta) - Rat Genome Database

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Gene: Cbfb (core-binding factor subunit beta) Rattus norvegicus
Analyze
Symbol: Cbfb
Name: core-binding factor subunit beta
RGD ID: 620493
Description: Enables DNA binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II; protein polyubiquitination; and regulation of alpha-beta T cell differentiation. Predicted to act upstream of or within several processes, including hemopoiesis; osteoblast differentiation; and positive regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of core-binding activity factor complex. Human ortholog(s) of this gene implicated in acute myelomonocytic leukemia. Orthologous to human CBFB (core-binding factor subunit beta); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3H-1,2-dithiole-3-thione; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: core binding factor beta; core-binding factor, beta subunit; LOC361391; Pebp2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81949,955,133 - 50,002,661 (+)NCBIGRCr8
mRatBN7.21933,049,162 - 33,092,752 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1933,049,172 - 33,092,751 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1939,864,114 - 39,907,675 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01940,518,019 - 40,561,581 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01942,807,448 - 42,851,345 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01937,127,508 - 37,171,075 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1937,127,508 - 37,171,069 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01947,993,674 - 48,037,240 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41934,985,879 - 35,029,446 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11934,990,759 - 35,034,323 (+)NCBI
Celera1932,478,363 - 32,521,922 (+)NCBICelera
Cytogenetic Map19q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. The mood-stabilizing agents lithium and valproate robustly increase the levels of the neuroprotective protein bcl-2 in the CNS. Chen G, etal., J Neurochem 1999 Feb;72(2):879-82.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Fusion between transcription factor CBF beta/PEBP2 beta and a myosin heavy chain in acute myeloid leukemia. Liu P, etal., Science. 1993 Aug 20;261(5124):1041-4.
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. Down-regulation of RUNX1, RUNX3 and CBFbeta in hepatocellular carcinomas in an early stage of hepatocarcinogenesis. Miyagawa K, etal., Anticancer Res. 2006 Sep-Oct;26(5B):3633-43.
6. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
7. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
8. GOA pipeline RGD automated data pipeline
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
10. Comprehensive gene review and curation RGD comprehensive gene curation
11. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:9159135   PMID:12434155   PMID:12434156   PMID:14634060   PMID:18258917   PMID:19946888   PMID:20197312   PMID:22190036  


Genomics

Comparative Map Data
Cbfb
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81949,955,133 - 50,002,661 (+)NCBIGRCr8
mRatBN7.21933,049,162 - 33,092,752 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1933,049,172 - 33,092,751 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1939,864,114 - 39,907,675 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01940,518,019 - 40,561,581 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01942,807,448 - 42,851,345 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01937,127,508 - 37,171,075 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1937,127,508 - 37,171,069 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01947,993,674 - 48,037,240 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41934,985,879 - 35,029,446 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11934,990,759 - 35,034,323 (+)NCBI
Celera1932,478,363 - 32,521,922 (+)NCBICelera
Cytogenetic Map19q11NCBI
CBFB
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381667,029,149 - 67,101,058 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1667,028,984 - 67,101,058 (+)EnsemblGRCh38hg38GRCh38
GRCh371667,063,052 - 67,134,961 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361665,620,551 - 65,692,462 (+)NCBINCBI36Build 36hg18NCBI36
Celera1651,571,303 - 51,643,220 (+)NCBICelera
Cytogenetic Map16q22.1NCBI
HuRef1652,937,018 - 53,008,911 (+)NCBIHuRef
CHM1_11668,470,009 - 68,542,269 (+)NCBICHM1_1
T2T-CHM13v2.01672,823,442 - 72,895,354 (+)NCBIT2T-CHM13v2.0
Cbfb
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm398105,897,306 - 105,944,621 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl8105,897,306 - 105,944,621 (+)EnsemblGRCm39 Ensembl
GRCm388105,170,674 - 105,217,989 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl8105,170,674 - 105,217,989 (+)EnsemblGRCm38mm10GRCm38
MGSCv378107,694,574 - 107,741,889 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv368108,059,803 - 108,107,115 (+)NCBIMGSCv36mm8
Celera8109,393,261 - 109,440,736 (+)NCBICelera
Cytogenetic Map8D3NCBI
cM Map853.04NCBI
Cbfb
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554849,503,227 - 9,557,066 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554849,503,286 - 9,557,066 (-)NCBIChiLan1.0ChiLan1.0
CBFB
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21876,557,314 - 76,630,904 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11682,469,878 - 82,542,838 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01647,373,543 - 47,446,783 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11666,800,463 - 66,836,371 (+)NCBIpanpan1.1PanPan1.1panPan2
CBFB
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1582,253,496 - 82,313,765 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl582,255,617 - 82,313,168 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha582,241,909 - 82,302,204 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0582,689,867 - 82,750,223 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl582,689,765 - 82,750,372 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1582,513,894 - 82,574,184 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0582,199,231 - 82,259,510 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0582,838,753 - 82,899,077 (-)NCBIUU_Cfam_GSD_1.0
Cbfb
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934941,999,786 - 42,051,838 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647517,537,236 - 17,589,330 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647517,537,273 - 17,589,383 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CBFB
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl627,684,030 - 27,750,852 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1627,684,320 - 27,750,856 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
CBFB
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1560,356,303 - 60,445,793 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl560,356,272 - 60,445,729 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604723,107,240 - 23,186,969 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Cbfb
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474619,204,392 - 19,264,194 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474619,204,415 - 19,264,217 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Cbfb
59 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:301
Count of miRNA genes:160
Interacting mature miRNAs:225
Transcripts:ENSRNOT00000019656
Prediction methods:Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
61447Tcas1Tongue tumor susceptibility QTL 16.08tongue integrity trait (VT:0010553)squamous cell carcinoma of the tongue maximum tumor diameter (CMO:0001875)19231612147316121Rat
9590298Uminl5Urine mineral level QTL 53.590.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)19136824771Rat
724546Kidm3Kidney mass QTL 33.1kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)192932249057337602Rat
1331737Uae29Urinary albumin excretion QTL 295.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)19409615555283277Rat
2298478Eau8Experimental allergic uveoretinitis QTL 80.0163uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)191715443357337602Rat
61328Eae8Experimental allergic encephalomyelitis QTL 84nervous system integrity trait (VT:0010566)percentage of study population developing experimental autoimmune encephalomyelitis during a period of time (CMO:0001047)192481604133061905Rat
1578764Stresp19Stress response QTL 193.60.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)191563020157337602Rat
1558656Prcs1Prostate cancer susceptibility QTL 15prostate integrity trait (VT:0010571)percentage of study population developing ventral prostate tumorous lesions during a period of time (CMO:0000943)191511459834521833Rat
1331788Rf45Renal function QTL 452.818kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)191560502346559041Rat
9590090Insglur8Insulin/glucose ratio QTL 810.810.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)19136824771Rat
1549835Tcas7Tongue tumor susceptibility QTL 70.001tongue integrity trait (VT:0010553)squamous cell carcinoma of the head and neck tumor number (CMO:0001876)192481797839654489Rat
724566Uae12Urinary albumin excretion QTL 125urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)19218792756457239Rat
1354633Bw28Body weight QTL 286.04body mass (VT:0001259)body weight (CMO:0000012)192753020737947399Rat
724565Tcas5Tongue tumor susceptibility QTL 510.04tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)19997775339654489Rat
8552935Pigfal10Plasma insulin-like growth factor 1 level QTL 105.7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)19136824771Rat
61350Bp32Blood pressure QTL 320.012arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)192048357557337602Rat
7411549Bw130Body weight QTL 13050.001body mass (VT:0001259)body weight gain (CMO:0000420)191545586057337602Rat
724518Uae19Urinary albumin excretion QTL 195.5urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)19745724942983518Rat
8694186Bw152Body weight QTL 1523.340.001body mass (VT:0001259)body weight gain (CMO:0000420)1956937445569374Rat
61423Cia14Collagen induced arthritis QTL 143joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)191082797043544039Rat
9590250Scort11Serum corticosterone level QTL 1123.450.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)19136824771Rat
1354607Gmadr1Adrenal mass QTL 15.83adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)192753020737947399Rat
2317848Alcrsp21Alcohol response QTL 211.8999999761581420.05response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)19320477748204777Rat
1354600Salc2Saline consumption QTL 29.910.001drinking behavior trait (VT:0001422)saline drink intake rate (CMO:0001627)192753020737947399Rat
9589102Slep13Serum leptin concentration QTL 134.630.001blood leptin amount (VT:0005667)plasma leptin level (CMO:0000781)1956937445569374Rat
7247442Uae39Urinary albumin excretion QTL 39urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)19218792746708701Rat

Markers in Region
D19Mit5  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21933,061,792 - 33,061,905 (+)MAPPERmRatBN7.2
Rnor_6.01937,140,123 - 37,140,233NCBIRnor6.0
Rnor_5.01948,006,288 - 48,006,398UniSTSRnor5.0
RGSC_v3.41934,998,494 - 34,998,604RGDRGSC3.4
RGSC_v3.41934,998,494 - 34,998,604UniSTSRGSC3.4
RGSC_v3.11935,003,375 - 35,003,485RGD
Celera1932,490,973 - 32,491,083UniSTS
Cytogenetic Map19q11UniSTS
AI179238  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21933,081,071 - 33,081,162 (+)MAPPERmRatBN7.2
Rnor_6.01937,159,395 - 37,159,485NCBIRnor6.0
Rnor_5.01948,025,562 - 48,025,652UniSTSRnor5.0
RGSC_v3.41935,017,767 - 35,017,857UniSTSRGSC3.4
Celera1932,510,244 - 32,510,334UniSTS
RH 3.4 Map19362.91UniSTS
Cytogenetic Map19q11UniSTS
RH137355  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21933,091,883 - 33,092,091 (+)MAPPERmRatBN7.2
Rnor_6.01937,170,207 - 37,170,414NCBIRnor6.0
Rnor_5.01948,036,372 - 48,036,579UniSTSRnor5.0
RGSC_v3.41935,028,580 - 35,028,787UniSTSRGSC3.4
Celera1932,521,056 - 32,521,263UniSTS
RH 3.4 Map19360.41UniSTS
Cytogenetic Map19q11UniSTS


Sequence


Ensembl Acc Id: ENSRNOT00000019656   ⟹   ENSRNOP00000019656
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1933,049,172 - 33,092,741 (+)Ensembl
Rnor_6.0 Ensembl1937,127,508 - 37,171,069 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000105373   ⟹   ENSRNOP00000097999
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1933,049,280 - 33,092,751 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000110232   ⟹   ENSRNOP00000089246
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1933,049,280 - 33,092,751 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000114057   ⟹   ENSRNOP00000082219
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1933,049,172 - 33,090,715 (+)Ensembl
RefSeq Acc Id: NM_001013191   ⟹   NP_001013209
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81949,959,096 - 50,002,661 (+)NCBI
mRatBN7.21933,049,179 - 33,092,750 (+)NCBI
Rnor_6.01937,127,508 - 37,171,073 (+)NCBI
Rnor_5.01947,993,674 - 48,037,240 (+)NCBI
RGSC_v3.41934,985,879 - 35,029,446 (+)RGD
Celera1932,478,363 - 32,521,922 (+)RGD
Sequence:
RefSeq Acc Id: XM_006255502   ⟹   XP_006255564
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81949,955,133 - 50,002,661 (+)NCBI
mRatBN7.21933,049,162 - 33,092,752 (+)NCBI
Rnor_6.01937,127,513 - 37,171,075 (+)NCBI
Rnor_5.01947,993,674 - 48,037,240 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039097826   ⟹   XP_038953754
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81949,959,820 - 50,002,661 (+)NCBI
mRatBN7.21933,049,928 - 33,092,752 (+)NCBI
RefSeq Acc Id: XM_039097827   ⟹   XP_038953755
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81949,959,829 - 50,002,661 (+)NCBI
mRatBN7.21933,049,936 - 33,092,752 (+)NCBI
RefSeq Acc Id: NP_001013209   ⟸   NM_001013191
- UniProtKB: Q66HA7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006255564   ⟸   XM_006255502
- Peptide Label: isoform X1
- UniProtKB: A0A8I5ZT73 (UniProtKB/TrEMBL),   A0A8I6GMB2 (UniProtKB/TrEMBL),   A6IYM1 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000019656   ⟸   ENSRNOT00000019656
RefSeq Acc Id: XP_038953754   ⟸   XM_039097826
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038953755   ⟸   XM_039097827
- Peptide Label: isoform X3
Ensembl Acc Id: ENSRNOP00000082219   ⟸   ENSRNOT00000114057
Ensembl Acc Id: ENSRNOP00000089246   ⟸   ENSRNOT00000110232
Ensembl Acc Id: ENSRNOP00000097999   ⟸   ENSRNOT00000105373

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q66HA7-F1-model_v2 AlphaFold Q66HA7 1-182 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13701064
Promoter ID:EPDNEW_R11588
Type:initiation region
Name:Cbfb_1
Description:core-binding factor, beta subunit
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R11589  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01937,127,543 - 37,127,603EPDNEW
RGD ID:13701065
Promoter ID:EPDNEW_R11589
Type:initiation region
Name:Cbfb_2
Description:core-binding factor, beta subunit
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R11588  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01937,127,750 - 37,127,810EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:620493 AgrOrtholog
BioCyc Gene G2FUF-5856 BioCyc
Ensembl Genes ENSRNOG00000014647 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000019656.5 UniProtKB/TrEMBL
  ENSRNOT00000105373.1 UniProtKB/TrEMBL
  ENSRNOT00000110232.1 UniProtKB/TrEMBL
  ENSRNOT00000114057.1 UniProtKB/TrEMBL
Gene3D-CATH 2.40.250.10 UniProtKB/TrEMBL
InterPro CBF_beta UniProtKB/TrEMBL
  CBF_bsu_sf UniProtKB/TrEMBL
KEGG Report rno:361391 UniProtKB/TrEMBL
NCBI Gene Cbfb ENTREZGENE
PANTHER CBF_beta UniProtKB/TrEMBL
  CORE-BINDING FACTOR SUBUNIT BETA UniProtKB/TrEMBL
Pfam CBF_beta UniProtKB/TrEMBL
PhenoGen Cbfb PhenoGen
RatGTEx ENSRNOG00000014647 RatGTEx
Superfamily-SCOP CBF_beta UniProtKB/TrEMBL
UniProt A0A8I5ZT73 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AB92_RAT UniProtKB/TrEMBL
  A0A8I6GMB2 ENTREZGENE, UniProtKB/TrEMBL
  A6IYM1 ENTREZGENE, UniProtKB/TrEMBL
  Q66HA7 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2018-05-03 Cbfb  core-binding factor subunit beta  Cbfb  core-binding factor, beta subunit  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-09-18 Cbfb  core-binding factor, beta subunit  Cbfb  core binding factor beta  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-04-19 Cbfb  core binding factor beta  Cbfb_predicted  core binding factor beta (predicted)  Data merged from RGD:1309963 737654 APPROVED
2005-01-20 Cbfb  core binding factor beta      Symbol and Name status set to approved 1299863 APPROVED
2005-01-12 Cbfb_predicted  core binding factor beta (predicted)      Symbol and Name status set to approved 70820 APPROVED
2002-08-07 Cbfb  core binding factor beta      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_regulation mRNA is increased in the frontal cortex by mood-stabilizing agents, lithium and valproate 634635