Nop58 (NOP58 ribonucleoprotein) - Rat Genome Database

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Gene: Nop58 (NOP58 ribonucleoprotein) Rattus norvegicus
Analyze
Symbol: Nop58
Name: NOP58 ribonucleoprotein
RGD ID: 620484
Description: Predicted to enable ATPase binding activity; TFIID-class transcription factor complex binding activity; and snoRNA binding activity. Predicted to be involved in ribosomal small subunit biogenesis and snoRNA localization. Predicted to be located in Cajal body; cytosol; and fibrillar center. Predicted to be part of box C/D methylation guide snoRNP complex; pre-snoRNP complex; and small-subunit processome. Orthologous to human NOP58 (NOP58 ribonucleoprotein); PARTICIPATES IN ribosome biogenesis pathway; INTERACTS WITH (+)-schisandrin B; 2,4-dinitrotoluene; 3,3',4,4',5-pentachlorobiphenyl.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: MGC105440; Nap65; Nol5; NOP58 ribonucleoprotein homolog; NOP58 ribonucleoprotein homolog (yeast); Nopp140 associated protein; nopp140-associated protein of 65 kDa; nucleolar protein 5; nucleolar protein 58; nucleolar protein NOP58
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8968,614,992 - 68,638,911 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl968,615,010 - 68,638,909 (+)EnsemblGRCr8
mRatBN7.2961,120,939 - 61,144,810 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl961,120,929 - 61,144,810 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx969,615,623 - 69,639,722 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0974,731,599 - 74,755,698 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0973,049,892 - 73,073,989 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0966,495,881 - 66,520,521 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl966,495,832 - 66,519,788 (+)Ensemblrn6Rnor6.0
Rnor_5.0966,300,036 - 66,323,766 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4958,255,685 - 58,279,522 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera958,555,582 - 58,579,638 (+)NCBICelera
RGSC_v3.1958,402,666 - 58,426,502 (+)NCBI
Cytogenetic Map9q31NCBI
JBrowse:




Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
(1->4)-beta-D-glucan  (ISO)
1,2,4-trichloro-5-(2,5-dichlorophenyl)benzene  (ISO)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,4,4'-trichlorobiphenyl  (ISO)
2,4-dinitrotoluene  (EXP)
2,6-dimethoxyphenol  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (EXP)
3,4-methylenedioxymethamphetamine  (EXP)
3-chloropropane-1,2-diol  (EXP)
3-methylcholanthrene  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
acrylamide  (ISO)
all-trans-retinoic acid  (ISO)
amitrole  (EXP)
ammonium chloride  (EXP)
antimycin A  (ISO)
antirheumatic drug  (ISO)
aristolochic acid A  (ISO)
Aroclor 1254  (ISO)
atrazine  (ISO)
benzo[a]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol AF  (ISO)
buspirone  (EXP)
cadmium dichloride  (EXP)
caffeine  (ISO)
calcitriol  (ISO)
carbon nanotube  (ISO)
casticin  (ISO)
chloropicrin  (ISO)
chloroprene  (EXP)
chromium(6+)  (ISO)
cisplatin  (ISO)
copper(II) sulfate  (ISO)
coumarin  (ISO)
cyclosporin A  (ISO)
deguelin  (ISO)
deoxynivalenol  (ISO)
dibutyl phthalate  (EXP,ISO)
dicrotophos  (ISO)
diethylstilbestrol  (ISO)
dioxygen  (ISO)
disodium selenite  (ISO)
enzyme inhibitor  (ISO)
ethyl methanesulfonate  (ISO)
fenthion  (ISO)
fluoranthene  (ISO)
flutamide  (EXP)
folic acid  (ISO)
FR900359  (ISO)
furan  (ISO)
furfural  (ISO)
gamma-hexachlorocyclohexane  (EXP)
gentamycin  (EXP)
glafenine  (EXP)
hydrogen peroxide  (ISO)
hydroxyurea  (ISO)
indole-3-methanol  (EXP)
ivermectin  (ISO)
menadione  (ISO)
mercury dichloride  (EXP)
metformin  (EXP)
methidathion  (ISO)
methimazole  (EXP)
Monobutylphthalate  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
N-nitrosodiethylamine  (EXP)
Nivalenol  (ISO)
ozone  (ISO)
p-anisidine  (ISO)
paclitaxel  (ISO)
paracetamol  (ISO)
paraquat  (EXP)
PCB138  (ISO)
pentachlorophenol  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phenobarbital  (EXP)
phorone  (EXP)
picoxystrobin  (ISO)
pirinixic acid  (ISO)
poly(I:C)  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
pyrimidifen  (ISO)
resveratrol  (ISO)
rotenone  (EXP,ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sodium chloride  (ISO)
sodium dichromate  (EXP)
sodium fluoride  (ISO)
sulfadimethoxine  (EXP)
tamoxifen  (ISO)
tebufenpyrad  (ISO)
testosterone  (ISO)
tetrachloromethane  (EXP,ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
triadimefon  (EXP)
Tributyltin oxide  (ISO)
triphenyl phosphate  (EXP,ISO)
Triptolide  (ISO)
triptonide  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
zinc atom  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
4. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
5. GOA pipeline RGD automated data pipeline
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. Comprehensive gene review and curation RGD comprehensive gene curation
8. The box C/D and H/ACA snoRNPs: key players in the modification, processing and the dynamic folding of ribosomal RNA. Watkins NJ and Bohnsack MT, Wiley Interdiscip Rev RNA. 2012 May-Jun;3(3):397-414. doi: 10.1002/wrna.117. Epub 2011 Nov 7.
9. Conserved composition of mammalian box H/ACA and box C/D small nucleolar ribonucleoprotein particles and their interaction with the common factor Nopp140. Yang Y, etal., Mol Biol Cell 2000 Feb;11(2):567-77.
Additional References at PubMed
PMID:10925205   PMID:12477932   PMID:16687569   PMID:17636026   PMID:19946888   PMID:22082260   PMID:22658674   PMID:22681889  


Genomics

Comparative Map Data
Nop58
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8968,614,992 - 68,638,911 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl968,615,010 - 68,638,909 (+)EnsemblGRCr8
mRatBN7.2961,120,939 - 61,144,810 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl961,120,929 - 61,144,810 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx969,615,623 - 69,639,722 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0974,731,599 - 74,755,698 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0973,049,892 - 73,073,989 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0966,495,881 - 66,520,521 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl966,495,832 - 66,519,788 (+)Ensemblrn6Rnor6.0
Rnor_5.0966,300,036 - 66,323,766 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4958,255,685 - 58,279,522 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera958,555,582 - 58,579,638 (+)NCBICelera
RGSC_v3.1958,402,666 - 58,426,502 (+)NCBI
Cytogenetic Map9q31NCBI
NOP58
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382202,265,763 - 202,303,661 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2202,265,736 - 202,303,661 (+)Ensemblhg38GRCh38
GRCh372203,130,486 - 203,168,384 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362202,838,760 - 202,876,629 (+)NCBIBuild 36Build 36hg18NCBI36
Build 342202,956,020 - 202,993,888NCBI
Celera2196,882,417 - 196,920,291 (+)NCBICelera
Cytogenetic Map2q33.1NCBI
HuRef2194,979,023 - 195,015,805 (+)NCBIHuRef
CHM1_12203,136,987 - 203,174,808 (+)NCBICHM1_1
T2T-CHM13v2.02202,746,796 - 202,784,682 (+)NCBIT2T-CHM13v2.0
Nop58
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39159,724,165 - 59,751,352 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl159,724,130 - 59,758,203 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38159,684,961 - 59,711,510 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl159,684,971 - 59,719,044 (+)Ensemblmm10GRCm38
MGSCv37159,741,850 - 59,768,354 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36159,629,645 - 59,656,054 (+)NCBIMGSCv36mm8
Celera160,199,706 - 60,226,206 (+)NCBICelera
Cytogenetic Map1C2NCBI
cM Map130.38NCBI
Nop58
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545712,479,965 - 12,511,678 (-)Ensembl
ChiLan1.0NW_00495545712,481,467 - 12,511,678 (-)NCBIChiLan1.0ChiLan1.0
NOP58
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v213104,890,221 - 104,928,093 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B104,905,239 - 104,943,091 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B89,520,961 - 89,558,794 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B207,674,433 - 207,707,763 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B207,674,654 - 207,707,763 (+)EnsemblpanPan2panpan1.1
NOP58
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13711,255,562 - 11,287,325 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3711,255,589 - 11,287,279 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha3712,138,970 - 12,170,731 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.03711,191,615 - 11,223,536 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3711,191,646 - 11,223,757 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13711,142,546 - 11,173,876 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03711,121,045 - 11,152,921 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03711,114,468 - 11,146,228 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Nop58
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303159,486,721 - 159,517,681 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367261,457,002 - 1,486,530 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049367261,457,038 - 1,487,374 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NOP58
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl15105,893,637 - 105,930,459 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.115105,893,589 - 105,930,458 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.215117,351,116 - 117,380,896 (+)NCBISscrofa10.2Sscrofa10.2susScr3
NOP58
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11087,989,687 - 88,026,774 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1087,989,699 - 88,026,904 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_023666040111,362,208 - 111,399,710 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Nop58
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462476514,139,815 - 14,172,413 (-)NCBIHetGla 1.0HetGla 1.0hetGla2

Variants

.
Variants in Nop58
235 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:22
Count of miRNA genes:19
Interacting mature miRNAs:22
Transcripts:ENSRNOT00000022676
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2303170Bp332Blood pressure QTL 3323.730.027arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)9671488884474983Rat
631656Bp108Blood pressure QTL 1085.970.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)956047863101047863Rat
7411571Bw138Body weight QTL 13814.30.001body mass (VT:0001259)body weight gain (CMO:0000420)94002992585029925Rat
1582203Gluco19Glucose level QTL 193.30.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)963376862108376862Rat
1300180Bw14Body weight QTL 143.776body mass (VT:0001259)body weight (CMO:0000012)93125043268875676Rat
8662828Vetf6Vascular elastic tissue fragility QTL 63.9artery integrity trait (VT:0010639)patent ductus arteriosus score (CMO:0002566)94445825699506504Rat
724515Uae16Urinary albumin excretion QTL 168urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)965657365108376720Rat
61450Ciaa3CIA Autoantibody QTL 36.5blood autoantibody amount (VT:0003725)calculated serum anti-type 2 collagen antibody titer (CMO:0001279)92956766474567664Rat
1598834Memor11Memory QTL 112.5exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)94445825685262605Rat
70186Niddm26Non-insulin dependent diabetes mellitus QTL 263.87blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)92956766483835942Rat
70218Cm28Cardiac mass QTL 288.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)94172029586720295Rat
724544Uae9Urinary albumin excretion QTL 94.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)964220169109220169Rat
2290450Scl57Serum cholesterol level QTL 574.15blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)944458256121768150Rat
1578760Cm53Cardiac mass QTL 533.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)964220169109220169Rat
1581580Uae34Urinary albumin excretion QTL 34urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)964220169109220169Rat
1581517Bp284Blood pressure QTL 284arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)93922018684220186Rat
731164Uae25Urinary albumin excretion QTL 253.50.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)948718864108376862Rat
7411656Foco26Food consumption QTL 269.80.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)94002992585029925Rat
1598849Memor17Memory QTL 172.2exploratory behavior trait (VT:0010471)difference between duration of physical contact or close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)95746049778547958Rat
4889943Bss90Bone structure and strength QTL 904.1tibia area (VT:1000281)tibia-fibula cortical bone endosteal cross-sectional area (CMO:0001722)95450650499506504Rat
1578757Pur6Proteinuria QTL 63.30.005urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)964220169109220169Rat
1641894Alcrsp12Alcohol response QTL 12response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)93496059079960590Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000022676   ⟹   ENSRNOP00000022676
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl968,615,010 - 68,638,909 (+)Ensembl
mRatBN7.2 Ensembl961,120,942 - 61,144,810 (+)Ensembl
Rnor_6.0 Ensembl966,495,832 - 66,519,769 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000091283   ⟹   ENSRNOP00000073311
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl968,615,033 - 68,638,907 (+)Ensembl
mRatBN7.2 Ensembl961,120,929 - 61,144,806 (+)Ensembl
Rnor_6.0 Ensembl966,495,840 - 66,519,788 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000099256   ⟹   ENSRNOP00000082410
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl961,121,671 - 61,144,810 (+)Ensembl
RefSeq Acc Id: NM_021754   ⟹   NP_068522
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8968,615,074 - 68,638,911 (+)NCBI
mRatBN7.2961,120,970 - 61,144,810 (+)NCBI
Rnor_6.0966,495,881 - 66,519,790 (+)NCBI
Rnor_5.0966,300,036 - 66,323,766 (+)NCBI
RGSC_v3.4958,255,685 - 58,279,522 (+)RGD
Celera958,555,582 - 58,579,638 (+)RGD
Sequence:
RefSeq Acc Id: XM_063267663   ⟹   XP_063123733
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8968,614,992 - 68,638,911 (+)NCBI
RefSeq Acc Id: XM_063267664   ⟹   XP_063123734
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8968,618,608 - 68,638,911 (+)NCBI
RefSeq Acc Id: NP_068522   ⟸   NM_021754
- UniProtKB: O88525 (UniProtKB/Swiss-Prot),   Q9QZ86 (UniProtKB/Swiss-Prot),   A6IPB2 (UniProtKB/TrEMBL),   A0A8I5ZV87 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000073311   ⟸   ENSRNOT00000091283
Ensembl Acc Id: ENSRNOP00000022676   ⟸   ENSRNOT00000022676
Ensembl Acc Id: ENSRNOP00000082410   ⟸   ENSRNOT00000099256
RefSeq Acc Id: XP_063123733   ⟸   XM_063267663
- Peptide Label: isoform X1
- UniProtKB: A0A8I5ZV87 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063123734   ⟸   XM_063267664
- Peptide Label: isoform X2
Protein Domains
Nop

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9QZ86-F1-model_v2 AlphaFold Q9QZ86 1-534 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13696709
Promoter ID:EPDNEW_R7228
Type:initiation region
Name:Nop58_1
Description:NOP58 ribonucleoprotein
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0966,495,853 - 66,495,913EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:620484 AgrOrtholog
BioCyc Gene G2FUF-27403 BioCyc
Ensembl Genes ENSRNOG00000016486 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000022676 ENTREZGENE
  ENSRNOT00000022676.7 UniProtKB/Swiss-Prot
Gene3D-CATH 1.10.246.90 UniProtKB/Swiss-Prot
  1.10.287.4070 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7309062 IMAGE-MGC_LOAD
InterPro Nop56/Nop58 UniProtKB/Swiss-Prot
  NOP5_N UniProtKB/Swiss-Prot
  Nop_C UniProtKB/Swiss-Prot
  Nop_dom UniProtKB/Swiss-Prot
  Nop_dom_sf UniProtKB/Swiss-Prot
  NOSIC UniProtKB/Swiss-Prot
KEGG Report rno:60373 UniProtKB/Swiss-Prot
MGC_CLONE MGC:105440 IMAGE-MGC_LOAD
NCBI Gene 60373 ENTREZGENE
PANTHER NUCLEOLAR PROTEIN 58 UniProtKB/Swiss-Prot
  PTHR10894 UniProtKB/Swiss-Prot
Pfam Nop UniProtKB/Swiss-Prot
  NOP5NT UniProtKB/Swiss-Prot
PhenoGen Nop58 PhenoGen
PROSITE NOP UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000016486 RatGTEx
SMART NOSIC UniProtKB/Swiss-Prot
Superfamily-SCOP SSF89124 UniProtKB/Swiss-Prot
UniProt A0A8I5ZV87 ENTREZGENE, UniProtKB/TrEMBL
  A6IPB2 ENTREZGENE, UniProtKB/TrEMBL
  A6IPB3_RAT UniProtKB/TrEMBL
  NOP58_RAT UniProtKB/Swiss-Prot
  O88525 ENTREZGENE
  Q5PPK6_RAT UniProtKB/TrEMBL
  Q9QZ86 ENTREZGENE
UniProt Secondary O88525 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2012-12-18 Nop58  NOP58 ribonucleoprotein  Nop58  NOP58 ribonucleoprotein homolog (yeast)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2012-05-03 Nop58  NOP58 ribonucleoprotein homolog (yeast)  Nop58  nucleolar protein NOP58  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2009-10-22 Nop58  nucleolar protein NOP58  Nol5  nucleolar protein 5  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-20 Nol5  nucleolar protein 5  Nap65  Nopp140 associated protein  Symbol and Name updated 1299863 APPROVED
2002-08-07 Nap65  Nopp140 associated protein      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_homology has homology with yeast Nop5/58p 633515
gene_physical_interaction interacts with Nopp140 633515