Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Septin7 | Rat | (S)-nicotine | multiple interactions | ISO | Septin7 (Mus musculus) | 6480464 | [Nicotine co-treated with 1-Methyl-4-phenyl-1 more ... | CTD | PMID:20230807 | Septin7 | Rat | 1,2-dimethylhydrazine | decreases expression | ISO | Septin7 (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of SEPTIN7 mRNA | CTD | PMID:22206623 | Septin7 | Rat | 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine | increases expression | ISO | Septin7 (Mus musculus) | 6480464 | 1-Methyl-4-phenyl-1 more ... | CTD | PMID:20230807 | Septin7 | Rat | 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine | multiple interactions | ISO | Septin7 (Mus musculus) | 6480464 | [Caffeine co-treated with 1-Methyl-4-phenyl-1 more ... | CTD | PMID:20230807 | Septin7 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of SEPTIN7 mRNA | CTD | PMID:33387578 | Septin7 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of SEPTIN7 mRNA | CTD | PMID:34747641 | Septin7 | Rat | 4-hydroxyphenyl retinamide | decreases expression | ISO | Septin7 (Mus musculus) | 6480464 | Fenretinide results in decreased expression of SEPTIN7 mRNA | CTD | PMID:28973697 | Septin7 | Rat | actinomycin D | multiple interactions | ISO | SEPTIN7 (Homo sapiens) | 6480464 | [Dactinomycin co-treated with nutlin 3] results in increased secretion of SEPTIN7 protein | CTD | PMID:38460933 | Septin7 | Rat | aflatoxin M1 | decreases expression | ISO | SEPTIN7 (Homo sapiens) | 6480464 | Aflatoxin M1 results in decreased expression of SEPTIN7 mRNA | CTD | PMID:30928695 | Septin7 | Rat | all-trans-retinoic acid | decreases expression | ISO | SEPTIN7 (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of SEPTIN7 mRNA | CTD | PMID:33167477 | Septin7 | Rat | amitrole | decreases expression | EXP | | 6480464 | Amitrole results in decreased expression of SEPTIN7 mRNA | CTD | PMID:38685447 | Septin7 | Rat | ammonium chloride | affects expression | EXP | | 6480464 | Ammonium Chloride affects the expression of SEPTIN7 mRNA | CTD | PMID:16483693 | Septin7 | Rat | antirheumatic drug | increases expression | ISO | SEPTIN7 (Homo sapiens) | 6480464 | Antirheumatic Agents results in increased expression of SEPTIN7 mRNA | CTD | PMID:24449571 | Septin7 | Rat | aristolochic acid A | decreases expression | ISO | SEPTIN7 (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of SEPTIN7 mRNA | CTD | PMID:33212167 | Septin7 | Rat | arsenous acid | increases expression | ISO | SEPTIN7 (Homo sapiens) | 6480464 | Arsenic Trioxide results in increased expression of SEPTIN7 mRNA | CTD | PMID:20458559 | Septin7 | Rat | atrazine | multiple interactions | ISO | SEPTIN7 (Homo sapiens) | 6480464 | [Atrazine co-treated with Arsenates] results in increased expression of SEPTIN7 mRNA | CTD | PMID:18585445 | Septin7 | Rat | benzo[a]pyrene diol epoxide I | increases expression | ISO | SEPTIN7 (Homo sapiens) | 6480464 | 7 more ... | CTD | PMID:20382639 | Septin7 | Rat | beta-lapachone | decreases expression | ISO | SEPTIN7 (Homo sapiens) | 6480464 | beta-lapachone results in decreased expression of SEPT7 mRNA | CTD | PMID:38218311 | Septin7 | Rat | bisphenol A | affects expression | EXP | | 6480464 | bisphenol A affects the expression of SEPTIN7 mRNA | CTD | PMID:25181051 | Septin7 | Rat | bisphenol A | decreases expression | ISO | SEPTIN7 (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of SEPTIN7 protein | CTD | PMID:34186270 | Septin7 | Rat | bisphenol A | decreases expression | ISO | Septin7 (Mus musculus) | 6480464 | bisphenol A results in decreased expression of SEPTIN7 mRNA | CTD | PMID:33221593 | Septin7 | Rat | bisphenol A | increases expression | ISO | SEPTIN7 (Homo sapiens) | 6480464 | bisphenol A results in increased expression of SEPTIN7 protein | CTD | PMID:37567409 | Septin7 | Rat | Bisphenol B | increases expression | ISO | SEPTIN7 (Homo sapiens) | 6480464 | bisphenol B results in increased expression of SEPTIN7 protein | CTD | PMID:34186270 | Septin7 | Rat | bisphenol F | increases expression | ISO | Septin7 (Mus musculus) | 6480464 | bisphenol F results in increased expression of SEPTIN7 mRNA | CTD | PMID:38685157 | Septin7 | Rat | buspirone | decreases expression | EXP | | 6480464 | Buspirone results in decreased expression of SEPTIN7 mRNA | CTD | PMID:24136188 | Septin7 | Rat | cadmium dichloride | increases expression | ISO | SEPTIN7 (Homo sapiens) | 6480464 | Cadmium Chloride results in increased expression of SEPTIN7 mRNA | CTD | PMID:12160620 and PMID:26472689 | Septin7 | Rat | caffeine | multiple interactions | ISO | Septin7 (Mus musculus) | 6480464 | [Caffeine co-treated with 1-Methyl-4-phenyl-1 more ... | CTD | PMID:20230807 | Septin7 | Rat | carbon nanotube | affects expression | ISO | Septin7 (Mus musculus) | 6480464 | Nanotubes and Carbon affects the expression of SEPTIN7 protein | CTD | PMID:21135415 | Septin7 | Rat | CGP 52608 | multiple interactions | ISO | SEPTIN7 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to SEPTIN7 gene] | CTD | PMID:28238834 | Septin7 | Rat | curcumin | increases expression | ISO | SEPTIN7 (Homo sapiens) | 6480464 | Curcumin results in increased expression of SEPTIN7 mRNA | CTD | PMID:16101141 | Septin7 | Rat | cyclosporin A | decreases methylation | ISO | SEPTIN7 (Homo sapiens) | 6480464 | Cyclosporine results in decreased methylation of SEPTIN7 promoter | CTD | PMID:27989131 | Septin7 | Rat | diarsenic trioxide | increases expression | ISO | SEPTIN7 (Homo sapiens) | 6480464 | Arsenic Trioxide results in increased expression of SEPTIN7 mRNA | CTD | PMID:20458559 | Septin7 | Rat | dicrotophos | decreases expression | ISO | SEPTIN7 (Homo sapiens) | 6480464 | dicrotophos results in decreased expression of SEPTIN7 mRNA | CTD | PMID:28302478 | Septin7 | Rat | dieldrin | affects expression | EXP | | 6480464 | Dieldrin affects the expression of SEPTIN7 mRNA | CTD | PMID:22546817 | Septin7 | Rat | disodium selenite | increases expression | ISO | SEPTIN7 (Homo sapiens) | 6480464 | Sodium Selenite results in increased expression of SEPTIN7 mRNA | CTD | PMID:18175754 | Septin7 | Rat | epoxiconazole | increases expression | ISO | Septin7 (Mus musculus) | 6480464 | epoxiconazole results in increased expression of SEPTIN7 mRNA | CTD | PMID:35436446 | Septin7 | Rat | ethanol | affects splicing | ISO | Septin7 (Mus musculus) | 6480464 | Ethanol affects the splicing of SEPTIN7 mRNA | CTD | PMID:30319688 | Septin7 | Rat | flavonoids | decreases expression | EXP | | 6480464 | Flavonoids results in decreased expression of SEPTIN7 mRNA | CTD | PMID:18035473 | Septin7 | Rat | flutamide | increases expression | EXP | | 6480464 | Flutamide results in increased expression of SEPTIN7 mRNA | CTD | PMID:24136188 | Septin7 | Rat | ivermectin | decreases expression | ISO | SEPTIN7 (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of SEPTIN7 protein | CTD | PMID:32959892 | Septin7 | Rat | kojic acid | decreases expression | ISO | SEPTIN7 (Homo sapiens) | 6480464 | kojic acid results in decreased expression of SEPTIN7 mRNA | CTD | PMID:16595896 | Septin7 | Rat | lead(0) | affects expression | ISO | SEPTIN7 (Homo sapiens) | 6480464 | Lead affects the expression of SEPTIN7 mRNA | CTD | PMID:28903495 | Septin7 | Rat | Mesaconitine | increases expression | EXP | | 6480464 | mesaconitine results in increased expression of SEPTIN7 protein | CTD | PMID:37182599 | Septin7 | Rat | morphine | multiple interactions | EXP | | 6480464 | Morphine deficiency inhibits the reaction [Morphine deficiency inhibits the reaction [Morphine results in decreased expression of SEPTIN7 protein]] and Morphine deficiency inhibits the reaction [Morphine results in decreased expression of SEPTIN7 protein] | CTD | PMID:23056601 | Septin7 | Rat | morphine | decreases expression | EXP | | 6480464 | Morphine results in decreased expression of SEPTIN7 protein | CTD | PMID:23056601 | Septin7 | Rat | N-methyl-4-phenylpyridinium | multiple interactions | ISO | SEPTIN7 (Homo sapiens) | 6480464 | U 0126 affects the reaction [1-Methyl-4-phenylpyridinium affects the expression of SEPTIN7 mRNA] | CTD | PMID:12710931 | Septin7 | Rat | N-methyl-4-phenylpyridinium | increases expression | ISO | SEPTIN7 (Homo sapiens) | 6480464 | 1-Methyl-4-phenylpyridinium results in increased expression of SEPTIN7 protein | CTD | PMID:24675778 | Septin7 | Rat | nickel dichloride | affects expression | EXP | | 6480464 | nickel chloride affects the expression of SEPTIN7 mRNA | CTD | PMID:22546817 | Septin7 | Rat | nicotine | multiple interactions | ISO | Septin7 (Mus musculus) | 6480464 | [Nicotine co-treated with 1-Methyl-4-phenyl-1 more ... | CTD | PMID:20230807 | Septin7 | Rat | nimesulide | decreases expression | EXP | | 6480464 | nimesulide results in decreased expression of SEPTIN7 mRNA | CTD | PMID:24136188 | Septin7 | Rat | Nutlin-3 | multiple interactions | ISO | SEPTIN7 (Homo sapiens) | 6480464 | [Dactinomycin co-treated with nutlin 3] results in increased secretion of SEPTIN7 protein | CTD | PMID:38460933 | Septin7 | Rat | pentachlorophenol | increases expression | ISO | Septin7 (Mus musculus) | 6480464 | Pentachlorophenol results in increased expression of SEPTIN7 mRNA | CTD | PMID:23892564 | Septin7 | Rat | potassium nitrate | decreases expression | ISO | SEPTIN7 (Homo sapiens) | 6480464 | potassium nitrate results in decreased expression of SEPTIN7 mRNA | CTD | PMID:15878651 | Septin7 | Rat | SB 431542 | multiple interactions | ISO | SEPTIN7 (Homo sapiens) | 6480464 | [LDN 193189 co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide co-treated with FGF2 protein] results in increased expression of SEPTIN7 protein | CTD | PMID:37664457 | Septin7 | Rat | silicon dioxide | decreases expression | ISO | SEPTIN7 (Homo sapiens) | 6480464 | Silicon Dioxide analog results in decreased expression of SEPTIN7 mRNA | CTD | PMID:25895662 | Septin7 | Rat | sodium arsenite | affects methylation | ISO | SEPTIN7 (Homo sapiens) | 6480464 | sodium arsenite affects the methylation of SEPTIN7 gene | CTD | PMID:28589171 | Septin7 | Rat | sodium arsenite | decreases expression | EXP | | 6480464 | sodium arsenite results in decreased expression of SEPTIN7 protein | CTD | PMID:29459688 | Septin7 | Rat | tetrachloromethane | increases expression | ISO | Septin7 (Mus musculus) | 6480464 | Carbon Tetrachloride results in increased expression of SEPTIN7 mRNA | CTD | PMID:31919559 | Septin7 | Rat | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of SEPTIN7 mRNA | CTD | PMID:34492290 | Septin7 | Rat | titanium dioxide | decreases methylation | ISO | Septin7 (Mus musculus) | 6480464 | titanium dioxide results in decreased methylation of SEPT7 gene more ... | CTD | PMID:35295148 | Septin7 | Rat | titanium dioxide | affects methylation | ISO | Septin7 (Mus musculus) | 6480464 | titanium dioxide affects the methylation of SEPT7 promoter | CTD | PMID:35295148 | Septin7 | Rat | trichloroethene | decreases expression | EXP | | 6480464 | Trichloroethylene results in decreased expression of SEPTIN7 mRNA | CTD | PMID:33387578 | Septin7 | Rat | triphenyl phosphate | affects expression | ISO | SEPTIN7 (Homo sapiens) | 6480464 | triphenyl phosphate affects the expression of SEPTIN7 mRNA | CTD | PMID:37042841 | Septin7 | Rat | valproic acid | decreases methylation | ISO | SEPTIN7 (Homo sapiens) | 6480464 | Valproic Acid results in decreased methylation of SEPTIN7 gene | CTD | PMID:29154799 | Septin7 | Rat | vinclozolin | affects expression | EXP | | 6480464 | vinclozolin affects the expression of SEPTIN7 mRNA | CTD | PMID:19015723 | Septin7 | Rat | vinclozolin | increases expression | EXP | | 6480464 | vinclozolin results in increased expression of SEPTIN7 mRNA | CTD | PMID:23034163 and PMID:23869203 | |