Myog (myogenin) - Rat Genome Database

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Gene: Myog (myogenin) Rattus norvegicus
Analyze
Symbol: Myog
Name: myogenin
RGD ID: 620432
Description: Exhibits RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including cellular response to magnetism; regulation of generation of precursor metabolites and energy; and response to stimulus involved in regulation of muscle adaptation. Localizes to nucleus and protein-DNA complex. Biomarker of obesity. Orthologous to human MYOG (myogenin); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: REVIEWED
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21345,745,455 - 45,748,044 (+)NCBI
Rnor_6.0 Ensembl1351,126,459 - 51,129,048 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01351,126,459 - 51,129,048 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01356,182,747 - 56,185,336 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41347,243,712 - 47,246,301 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11347,257,754 - 47,260,344 (+)NCBI
Celera1346,073,572 - 46,076,161 (+)NCBICelera
Cytogenetic Map13q13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
cell differentiation  (IEA)
cellular response to estradiol stimulus  (ISO,ISS)
cellular response to growth factor stimulus  (ISO)
cellular response to lithium ion  (ISO)
cellular response to magnetism  (IEP)
cellular response to retinoic acid  (IEP)
cellular response to tumor necrosis factor  (ISO)
histone H3 acetylation  (ISO)
histone H4 acetylation  (ISO)
muscle cell differentiation  (ISO)
muscle organ development  (IEA,ISO)
myoblast differentiation  (IEP)
myotube differentiation  (IMP,ISO)
negative regulation of cell population proliferation  (ISO,ISS)
negative regulation of glycolytic process  (IDA)
ossification  (ISO)
positive regulation of muscle atrophy  (ISO,ISS)
positive regulation of myoblast differentiation  (IBA,ISO,ISS)
positive regulation of myotube differentiation  (ISO,ISS)
positive regulation of oxidative phosphorylation  (IDA)
positive regulation of skeletal muscle fiber development  (IBA,ISO,ISS)
positive regulation of transcription by RNA polymerase II  (IBA,IDA,ISO,ISS)
positive regulation of transcription, DNA-templated  (ISO)
regulation of cell cycle  (ISO,ISS)
regulation of myoblast fusion  (ISO,ISS)
regulation of skeletal muscle satellite cell proliferation  (ISO,ISS)
regulation of transcription by RNA polymerase II  (IBA)
regulation of transcription, DNA-templated  (IEA)
response to denervation involved in regulation of muscle adaptation  (ISO,ISS)
response to electrical stimulus involved in regulation of muscle adaptation  (IDA,IEP)
response to gravity  (IEP)
response to muscle activity  (IEP)
response to muscle activity involved in regulation of muscle adaptation  (IDA)
skeletal muscle atrophy  (IEP)
skeletal muscle cell differentiation  (IBA)
skeletal muscle fiber development  (ISO)
skeletal muscle tissue development  (ISO)
skeletal muscle tissue regeneration  (IEP)
striated muscle atrophy  (ISO,ISS)

Cellular Component
nucleoplasm  (IEA,ISO)
nucleus  (IDA,IEA,ISO)
protein-DNA complex  (IDA)

References

References - curated
1. Arnold HH, etal., J Cell Biol. 1992 Aug;118(4):877-87.
2. Asher O, etal., FEBS Lett. 1992 Mar 24;299(1):15-8.
3. Castillero E, etal., Endocr Connect. 2012 Jun 8;1(1):1-12. doi: 10.1530/EC-12-0003. Print 2012 Jul 1.
4. Florini JR and Ewton DZ, J Biol Chem. 1990 Aug 15;265(23):13435-7.
5. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
6. GOA data from the GO Consortium
7. Hughes SM, etal., J Cell Biol. 1999 May 3;145(3):633-42.
8. Hyatt JP, etal., Am J Physiol Cell Physiol 2003 Nov;285(5):C1161-73. Epub 2003 Jul 2.
9. Ikeda S, etal., Arch Phys Med Rehabil 2003 Mar;84(3):419-23.
10. Inobe M, etal., J Appl Physiol 2002 May;92(5):1936-42.
11. Ishido M, etal., Acta Physiol Scand. 2004 Mar;180(3):281-9.
12. Jin Y, etal., Acta Neuropathol. 2000 Jun;99(6):619-27.
13. Macpherson PC, etal., J Cell Biochem. 2011 Aug;112(8):2149-59. doi: 10.1002/jcb.23136.
14. Mehiri SN, etal., Eur Respir J. 2005 Mar;25(3):422-30.
15. MGD data from the GO Consortium
16. NCBI rat LocusLink and RefSeq merged data July 26, 2002
17. Peterson JM, etal., Am J Physiol Cell Physiol. 2008 Aug;295(2):C521-8. Epub 2008 May 28.
18. Putman CT, etal., Am J Physiol Cell Physiol. 2000 Sep;279(3):C682-90.
19. RGD automated data pipeline
20. RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
21. RGD automated import pipeline for gene-chemical interactions
22. RGD comprehensive gene curation
23. Scarpa S, etal., Cell Growth Differ. 1996 Aug;7(8):1051-8.
24. Siu PM, etal., J Appl Physiol (1985). 2004 Jul;97(1):277-85. Epub 2004 Mar 19.
25. Tang H, etal., Cell Signal. 2004 May;16(5):551-63.
26. Yuge L and Kataoka K, In Vitro Cell Dev Biol Anim. 2000 Jun;36(6):383-6.
27. Zador E, etal., Biochim Biophys Acta 2002 Jun 12;1590(1-3):52-63.
Additional References at PubMed
PMID:2537150   PMID:8393145   PMID:8587605   PMID:8760303   PMID:10835421   PMID:11076940   PMID:12133506   PMID:12486129   PMID:14762206   PMID:15322112   PMID:15489316   PMID:15673614  
PMID:15706034   PMID:16140986   PMID:16554364   PMID:17531403   PMID:17904117   PMID:18849500   PMID:19319192   PMID:19783823   PMID:20384792   PMID:20399744   PMID:21177767   PMID:21858842  
PMID:22106411   PMID:22464481   PMID:22638570   PMID:22847234   PMID:23085379   PMID:24349514   PMID:24361185   PMID:24532688   PMID:25056796   PMID:25085416   PMID:26452256   PMID:26914683  


Genomics

Comparative Map Data
Myog
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21345,745,455 - 45,748,044 (+)NCBI
Rnor_6.0 Ensembl1351,126,459 - 51,129,048 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01351,126,459 - 51,129,048 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01356,182,747 - 56,185,336 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41347,243,712 - 47,246,301 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11347,257,754 - 47,260,344 (+)NCBI
Celera1346,073,572 - 46,076,161 (+)NCBICelera
Cytogenetic Map13q13NCBI
MYOG
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1203,083,129 - 203,086,012 (-)EnsemblGRCh38hg38GRCh38
GRCh381203,083,129 - 203,086,012 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371203,052,257 - 203,055,140 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361201,318,880 - 201,322,000 (-)NCBINCBI36hg18NCBI36
Build 341199,783,916 - 199,786,823NCBI
Celera1176,181,515 - 176,184,632 (-)NCBI
Cytogenetic Map1q32.1NCBI
HuRef1174,217,862 - 174,220,769 (-)NCBIHuRef
CHM1_11204,474,600 - 204,477,509 (-)NCBICHM1_1
Myog
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391134,217,742 - 134,220,286 (+)NCBIGRCm39mm39
GRCm39 Ensembl1134,217,727 - 134,220,286 (+)Ensembl
GRCm381134,290,004 - 134,292,548 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1134,289,989 - 134,292,548 (+)EnsemblGRCm38mm10GRCm38
MGSCv371136,186,581 - 136,189,125 (+)NCBIGRCm37mm9NCBIm37
MGSCv361136,106,424 - 136,108,961 (+)NCBImm8
Celera1136,900,556 - 136,903,100 (+)NCBICelera
Cytogenetic Map1E4NCBI
cM Map158.18NCBI
Myog
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540639,099,716 - 39,102,501 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495540639,099,044 - 39,102,479 (-)NCBIChiLan1.0ChiLan1.0
MYOG
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11182,979,700 - 182,982,607 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1182,979,700 - 182,982,611 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01178,684,933 - 178,687,971 (-)NCBIMhudiblu_PPA_v0panPan3
MYOG
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.17112,116 - 114,604 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl7112,034 - 113,892 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha7167,989 - 170,338 (+)NCBI
ROS_Cfam_1.07122,772 - 125,124 (+)NCBI
UMICH_Zoey_3.17111,008 - 113,379 (+)NCBI
UNSW_CanFamBas_1.07220,521 - 222,887 (+)NCBI
UU_Cfam_GSD_1.07243,050 - 245,421 (+)NCBI
Myog
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934472,272,365 - 72,275,138 (+)NCBI
SpeTri2.0NW_0049365671,507,042 - 1,509,814 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MYOG
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl9113,782,469 - 113,785,362 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.19113,783,233 - 113,785,312 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.29125,243,803 - 125,245,882 (-)NCBISscrofa10.2Sscrofa10.2susScr3
Pig Cytomap9q2.1-q2.6NCBI
MYOG
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12526,264,872 - 26,269,652 (+)NCBI
ChlSab1.1 Ensembl2526,266,717 - 26,268,867 (+)Ensembl
Myog
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248077,742,926 - 7,753,149 (+)NCBI

Position Markers
PMC207566P7  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21345,745,282 - 45,745,492 (+)MAPPER
Rnor_6.01351,126,287 - 51,126,496NCBIRnor6.0
Rnor_5.01356,182,575 - 56,182,784UniSTSRnor5.0
RGSC_v3.41347,243,540 - 47,243,749UniSTSRGSC3.4
Celera1346,073,400 - 46,073,609UniSTS
Cytogenetic Map13q13UniSTS
Myog  
Rat AssemblyChrPosition (strand)SourceJBrowse
RGSC_v3.41347,244,008 - 47,245,508UniSTSRGSC3.4
Celera1346,073,868 - 46,075,368UniSTS
Cytogenetic Map13q13UniSTS
UniSTS:205458  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21345,745,649 - 45,745,922 (+)MAPPER
Rnor_6.01351,126,654 - 51,126,926NCBIRnor6.0
Rnor_5.01356,182,942 - 56,183,214UniSTSRnor5.0
RGSC_v3.41347,243,907 - 47,244,179UniSTSRGSC3.4
Celera1346,073,767 - 46,074,039UniSTS
Cytogenetic Map13q13UniSTS
UniSTS:234220  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21345,745,523 - 45,745,850 (+)MAPPER
Rnor_6.01351,126,528 - 51,126,854NCBIRnor6.0
Rnor_5.01356,182,816 - 56,183,142UniSTSRnor5.0
RGSC_v3.41347,243,781 - 47,244,107UniSTSRGSC3.4
Celera1346,073,641 - 46,073,967UniSTS
Cytogenetic Map13q13UniSTS
PMC133893P1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21345,745,628 - 45,746,580 (+)MAPPER
Rnor_6.01351,126,633 - 51,127,584NCBIRnor6.0
Rnor_5.01356,182,921 - 56,183,872UniSTSRnor5.0
RGSC_v3.41347,243,886 - 47,244,837UniSTSRGSC3.4
Celera1346,073,746 - 46,074,697UniSTS
Cytogenetic Map13q13UniSTS
UniSTS:463953  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21345,745,903 - 45,746,577 (+)MAPPER
Rnor_6.01351,126,908 - 51,127,581NCBIRnor6.0
Rnor_5.01356,183,196 - 56,183,869UniSTSRnor5.0
RGSC_v3.41347,244,161 - 47,244,834UniSTSRGSC3.4
Celera1346,074,021 - 46,074,694UniSTS
Cytogenetic Map13q13UniSTS
Myog  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21345,747,899 - 45,748,013 (+)MAPPER
Rnor_6.01351,128,904 - 51,129,017NCBIRnor6.0
Rnor_5.01356,185,192 - 56,185,305UniSTSRnor5.0
RGSC_v3.41347,246,157 - 47,246,270UniSTSRGSC3.4
Celera1346,076,017 - 46,076,130UniSTS
Cytogenetic Map13q13UniSTS
Myog  
Rat AssemblyChrPosition (strand)SourceJBrowse
RGSC_v3.41347,244,171 - 47,245,692UniSTSRGSC3.4
Celera1346,074,031 - 46,075,552UniSTS
Cytogenetic Map13q13UniSTS
Myog  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21345,745,488 - 45,745,673 (+)MAPPER
Rnor_6.01351,126,493 - 51,126,677NCBIRnor6.0
Rnor_5.01356,182,781 - 56,182,965UniSTSRnor5.0
RGSC_v3.41347,243,746 - 47,243,930UniSTSRGSC3.4
Celera1346,073,606 - 46,073,790UniSTS
Cytogenetic Map13q13UniSTS
Myog  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_5.01356,183,043 - 56,184,543UniSTSRnor5.0
RGSC_v3.41347,244,008 - 47,245,508UniSTSRGSC3.4
Celera1346,073,868 - 46,075,368UniSTS
Cytogenetic Map13q13UniSTS
Myog  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_5.01356,183,206 - 56,184,727UniSTSRnor5.0
RGSC_v3.41347,244,171 - 47,245,692UniSTSRGSC3.4
Celera1346,074,031 - 46,075,552UniSTS
Cytogenetic Map13q13UniSTS


QTLs in Region (Rnor_6.0)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)131107975663Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)131107975663Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)131107975663Rat
1581554Pur11Proteinuria QTL 11urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)13901690682995569Rat
1581573Uae36Urinary albumin excretion QTL 36urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)13901690682995569Rat
1581570Eae17Experimental allergic encephalomyelitis QTL 174.1nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)1312193394108478121Rat
9589141Insul28Insulin level QTL 2810.820.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)131409633059096330Rat
7411662Foco29Food consumption QTL 2920.80.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)131409633059096330Rat
2302275Gluco37Glucose level QTL 373.8blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)131444158251577031Rat
2317040Aia21Adjuvant induced arthritis QTL 212.75joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)131462463159624631Rat
2317046Aia8Adjuvant induced arthritis QTL 83.9700000286102295joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)131462463159624631Rat
631645Bp121Blood pressure QTL 1213.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)131981081464810814Rat
9589164Gluco66Glucose level QTL 666.670.001blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)132005247765052477Rat
1331784Bp222Blood pressure QTL 2222.944arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)132148248158537177Rat
7207885Glom27Glomerulus QTL 273.9kidney glomerulus integrity trait (VT:0010546)kidney crescentic glomeruli count to kidney normal glomeruli count ratio (CMO:0002139)1324502279108770533Rat
61391Bp5Blood pressure QTL 55.6arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)132800833873008338Rat
70170Eae14Experimental allergic encephalomyelitis QTL 140.0024nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)132858445273584452Rat
1558644Cm45Cardiac mass QTL 453.60.002heart mass (VT:0007028)heart wet weight (CMO:0000069)132907693474076934Rat
6893338Cm76Cardiac mass QTL 7600.99heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)132907693474076934Rat
1354621Rf47Renal function QTL 473.7kidney renin amount (VT:0010559)kidney renin level (CMO:0002166)1335301263107975663Rat
2301962Cm72Cardiac mass QTL 724.12heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)133614753364868393Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)133614753399968921Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133614753399968921Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)133614753399968921Rat
70181BpQTLcluster11Blood pressure QTL cluster 116.922arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)133614753399968921Rat
2303563Bw89Body weight QTL 896body mass (VT:0001259)body weight (CMO:0000012)133734634882346348Rat
61340Bp25Blood pressure QTL 254.20.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133937292784372927Rat
10755495Bp387Blood pressure QTL 3873.78arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133950130093652524Rat
4889861Pur29Proteinuria QTL 2913.80.005total urine protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)134231074486833540Rat
1331750Bp220Blood pressure QTL 2202.98arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)134231074487310744Rat
70220Bp55Blood pressure QTL 555.75arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)134250834587508345Rat
61349Bp31Blood pressure QTL 315.75arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)134250834587508345Rat
1549897Stresp12Stress response QTL 123.35stress-related behavior trait (VT:0010451)number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)134357571788575717Rat
619615Bp80Blood pressure QTL 800.0354arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134567662990676629Rat
4145117Mcs27Mammary carcinoma susceptibility QTL 270.0001mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)134877665553264877Rat
6893344Cm79Cardiac mass QTL 791.50.04heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)134905850767207219Rat
12879472Bp399Blood pressure QTL 399arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)135060922853264877Rat
12879441Bp396Blood pressure QTL 396arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)135108098996080989Rat

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:355
Count of miRNA genes:216
Interacting mature miRNAs:255
Transcripts:ENSRNOT00000042046
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 7 8 7 7
Low 16 12 6 7 6 1 3 6 17 7 1
Below cutoff 2 14 17 14 12 14 31 10 6 2

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000042046   ⟹   ENSRNOP00000039817
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1351,126,459 - 51,129,048 (+)Ensembl
RefSeq Acc Id: ENSRNOT00000087240   ⟹   ENSRNOP00000073308
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1351,126,459 - 51,129,048 (+)Ensembl
RefSeq Acc Id: NM_017115   ⟹   NP_058811
RefSeq Status: REVIEWED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21345,745,455 - 45,748,044 (+)NCBI
Rnor_6.01351,126,459 - 51,129,048 (+)NCBI
Rnor_5.01356,182,747 - 56,185,336 (+)NCBI
RGSC_v3.41347,243,712 - 47,246,301 (+)RGD
Celera1346,073,572 - 46,076,161 (+)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_058811 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA41662 (Get FASTA)   NCBI Sequence Viewer  
  AAC12644 (Get FASTA)   NCBI Sequence Viewer  
  EDM09735 (Get FASTA)   NCBI Sequence Viewer  
  P20428 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_058811   ⟸   NM_017115
- UniProtKB: P20428 (UniProtKB/Swiss-Prot),   O70425 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000073308   ⟸   ENSRNOT00000087240
RefSeq Acc Id: ENSRNOP00000039817   ⟸   ENSRNOT00000042046
Protein Domains
bHLH

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Strain Variation

Strain Sequence Variants (Rnor 6.0)
ACI/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
ACI/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
ACI/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
BBDP/Wor (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
BN/SsN (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
Buf/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
COP/CrCrl (MCW & UW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
University of Wisconsin (Dr. James Shull)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Charles River Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob) and UW Madison (Dr. James Shull)
F344/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
F344/NRrrc (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
FHH/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHH/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
FHL/EurMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
FHL/EurMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
GH/OmrMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
GK/Ox (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LE/Stm (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/Crl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LEW/NCrlBR (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LH/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LL/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
LN/MavRrrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
M520/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
MHS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MNS/Gib (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
MR/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
SBH/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBH/Ygl sequenced by MCW
SBH/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SBN/Ygl (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: SBN/Ygl sequenced by MCW
SBN/Ygl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHR/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SHRSP/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SR/JrHsd (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Harlan Laboratories
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SR/JrHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/Jr (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
SS/JrHsdMcwi (MCW)
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Sequenced By: Medical College of Wisconsin (Dr. Howard Jacob)
Platform: Illumina HiSeq 2000
Secondary Analysis: BWA v0.7.7 and GATK v3.2-2
Breeder: Medical College of Wisconsin
Description: Provided by the Medical College of Wisconsin (Dr. Howard Jacob)
SS/JrHsdMcwi (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WAG/Rij (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/Gcrc (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin
WKY/NCrl (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WKY/NHsd (RGD)
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Platform: Illumina HiSeq 2000
Secondary Analysis: BWA mem 0.7.15, GATK v.3.6-0
Description: Sequences from Atanur et al and Hermsen et al realigned to the Rnor 6.0 assembly and reanalyzed by RGD
WN/N (MCW)
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Sequenced By: Royal Netherland Academy of Arts and Sciences (Dr. Edwin Cuppen)
Max Delbruck Center for Molecular Medicine (Dr. Norbert Huebner)
Platform: SOLiD 4 and 5500
Secondary Analysis: liftOver (Batch Coordinate Conversion)--genome.ucsc.edu
Breeder: National Institutes of Health
Description: Founder strain for the heterogeneous stock (HS) rat population; SNPs from the RGSC 3.4 assembly were "lifted over" from RGSC 3.4 to Rnor 5.0 and from Rnor 5.0 to Rnor 6.0; Provided by Medical College of Wisconsin

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:620432 AgrOrtholog
Ensembl Genes ENSRNOG00000030743 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000039817 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOP00000073308 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000042046 ENTREZGENE, UniProtKB/TrEMBL
  ENSRNOT00000087240 UniProtKB/Swiss-Prot
Gene3D-CATH 4.10.280.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Basic UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  bHLH_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HLH_DNA-bd_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Myogenic_factor UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:29148 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 29148 ENTREZGENE
PANTHER PTHR11534 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Basic UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HLH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Myog PhenoGen
PROSITE BHLH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART BASIC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  HLH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF47459 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt MYOG_RAT UniProtKB/Swiss-Prot
  O70425 ENTREZGENE, UniProtKB/TrEMBL
  P20428 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2004-02-26 Myog  myogenin      Symbol and Name status set to approved 625702 APPROVED
2002-08-07 Myog        Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_regulation expression is increased with repetitive stretching of soleus muscles 727517