![]()
Imported Disease Annotations - MGIObject Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Pdlim3 | Rat | arrhythmogenic right ventricular cardiomyopathy | | ISS | Pdlim3 (Mus musculus) | 13592920 | | MouseDO | | |
|
![]()
Imported Disease Annotations - MGIObject Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Pdlim3 | Rat | arrhythmogenic right ventricular cardiomyopathy | | ISS | Pdlim3 (Mus musculus) | 13592920 | | MouseDO | | |
|
|
|
|
|
|
|
|
|
|
|
# | Reference Title | Reference Citation |
1. | Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. | Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27. |
2. | Rat ISS GO annotations from MGI mouse gene data--August 2006 | MGD data from the GO Consortium |
3. | Electronic Transfer of LocusLink and RefSeq Data | NCBI rat LocusLink and RefSeq merged data July 26, 2002 |
4. | ClinVar Automated Import and Annotation Pipeline | RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations |
5. | Data Import for Chemical-Gene Interactions | RGD automated import pipeline for gene-chemical interactions |
6. | Comprehensive gene review and curation | RGD comprehensive gene curation |
7. | Actinin-associated LIM protein: identification of a domain interaction between PDZ and spectrin-like repeat motifs. | Xia H, etal., J Cell Biol 1997 Oct 20;139(2):507-15. |
PMID:11238905 | PMID:11329061 | PMID:12477932 | PMID:15489334 | PMID:35352799 |
Pdlim3 (Rattus norvegicus - Norway rat) |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
PDLIM3 (Homo sapiens - human) |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Pdlim3 (Mus musculus - house mouse) |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Pdlim3 (Chinchilla lanigera - long-tailed chinchilla) |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
PDLIM3 (Pan paniscus - bonobo/pygmy chimpanzee) |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
PDLIM3 (Canis lupus familiaris - dog) |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Pdlim3 (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
PDLIM3 (Sus scrofa - pig) |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
PDLIM3 (Chlorocebus sabaeus - green monkey) |
|
||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Pdlim3 (Heterocephalus glaber - naked mole-rat) |
|
.
Variants in Pdlim3
239 total Variants ![]() |
The detailed report is available here: | ![]() | Full Report | ![]() | CSV | ![]() | TAB | ![]() | Printer |
miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/). For more information about miRGate, see PMID:25858286 or access the full paper here. |
The following QTLs overlap with this region. | ![]() | Full Report | ![]() | CSV | ![]() | TAB | ![]() | Printer | ![]() | Gviewer |
RH143054 |
|
||||||||||||||||||||||||||||||||||||||||
BF390733 |
|
alimentary part of gastrointestinal system
|
appendage
|
circulatory system
|
ectoderm
|
endocrine system
|
endoderm
|
exocrine system
|
hemolymphoid system
|
hepatobiliary system
|
integumental system
|
mesenchyme
|
mesoderm
|
nervous system
|
renal system
|
reproductive system
|
respiratory system
|
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
9 | 11 | 49 | 113 | 91 | 90 | 59 | 25 | 59 | 6 | 218 | 97 | 93 | 45 | 60 | 31 |
RefSeq Transcripts | NM_053650 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
XM_006253119 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
XM_006253120 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
GenBank Nucleotide | AC114502 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
AF002281 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
BC081703 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
CH473995 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
FQ215471 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles | |
JAXUCZ010000016 | (Get FASTA) | NCBI Sequence Viewer | Search GEO for Microarray Profiles |
Ensembl Acc Id: | ENSRNOT00000017054 ⟹ ENSRNOP00000017054 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
|
Ensembl Acc Id: | ENSRNOT00000017568 ⟹ ENSRNOP00000017568 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
|
Ensembl Acc Id: | ENSRNOT00000085535 ⟹ ENSRNOP00000075153 | ||||||||||||
Type: | CODING | ||||||||||||
Position: |
|
RefSeq Acc Id: | NM_053650 ⟹ NP_446102 | ||||||||||||||||||||||||||||
RefSeq Status: | VALIDATED | ||||||||||||||||||||||||||||
Type: | CODING | ||||||||||||||||||||||||||||
Position: |
|
||||||||||||||||||||||||||||
Sequence: |
RefSeq Acc Id: | XM_006253119 ⟹ XP_006253181 | ||||||||||||||||||||
Type: | CODING | ||||||||||||||||||||
Position: |
|
||||||||||||||||||||
Sequence: |
RefSeq Acc Id: | XM_006253120 ⟹ XP_006253182 | ||||||||||||||||||||
Type: | CODING | ||||||||||||||||||||
Position: |
|
||||||||||||||||||||
Sequence: |
Protein RefSeqs | NP_446102 | (Get FASTA) | NCBI Sequence Viewer |
XP_006253181 | (Get FASTA) | NCBI Sequence Viewer | |
XP_006253182 | (Get FASTA) | NCBI Sequence Viewer | |
GenBank Protein | AAC16671 | (Get FASTA) | NCBI Sequence Viewer |
AAH81703 | (Get FASTA) | NCBI Sequence Viewer | |
EDL78864 | (Get FASTA) | NCBI Sequence Viewer | |
EDL78865 | (Get FASTA) | NCBI Sequence Viewer | |
Ensembl Protein | ENSRNOP00000017054.2 | ||
ENSRNOP00000017568.4 | |||
ENSRNOP00000075153.2 | |||
GenBank Protein | Q66HS7 | (Get FASTA) | NCBI Sequence Viewer |
RefSeq Acc Id: | NP_446102 ⟸ NM_053650 |
- UniProtKB: | Q66HS7 (UniProtKB/Swiss-Prot), O70208 (UniProtKB/Swiss-Prot), D3ZFR7 (UniProtKB/TrEMBL), A6JPQ7 (UniProtKB/TrEMBL) |
- Sequence: |
RefSeq Acc Id: | XP_006253182 ⟸ XM_006253120 |
- Peptide Label: | isoform X2 |
- UniProtKB: | A0A0G2K9W2 (UniProtKB/TrEMBL) |
- Sequence: |
RefSeq Acc Id: | XP_006253181 ⟸ XM_006253119 |
- Peptide Label: | isoform X1 |
- UniProtKB: | A6JPQ8 (UniProtKB/TrEMBL), A0A0G2JSM3 (UniProtKB/TrEMBL) |
- Sequence: |
Ensembl Acc Id: | ENSRNOP00000075153 ⟸ ENSRNOT00000085535 |
Ensembl Acc Id: | ENSRNOP00000017054 ⟸ ENSRNOT00000017054 |
Ensembl Acc Id: | ENSRNOP00000017568 ⟸ ENSRNOT00000017568 |
Name | Modeler | Protein Id | AA Range | Protein Structure |
AF-Q66HS7-F1-model_v2 | AlphaFold | Q66HS7 | 1-362 | view protein structure |
eQTL | View at Phenogen | |
WGCNA | View at Phenogen | |
Tissue/Strain Expression | View at Phenogen |
RGD ID: | 13700111 | ||||||||
Promoter ID: | EPDNEW_R10629 | ||||||||
Type: | single initiation site | ||||||||
Name: | Pdlim3_1 | ||||||||
Description: | PDZ and LIM domain 3 | ||||||||
SO ACC ID: | SO:0000170 | ||||||||
Source: | EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/) | ||||||||
Experiment Methods: | Single-end sequencing. | ||||||||
Position: |
|
Database | Acc Id | Source(s) |
AGR Gene | RGD:620427 | AgrOrtholog |
BioCyc Gene | G2FUF-11328 | BioCyc |
Ensembl Genes | ENSRNOG00000012658 | Ensembl, UniProtKB/TrEMBL |
Ensembl Transcript | ENSRNOT00000017054.7 | UniProtKB/TrEMBL |
ENSRNOT00000017568.8 | UniProtKB/TrEMBL | |
ENSRNOT00000085535.2 | UniProtKB/TrEMBL | |
Gene3D-CATH | 2.30.42.10 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
Cysteine Rich Protein | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
IMAGE_CLONE | IMAGE:7193873 | IMAGE-MGC_LOAD |
InterPro | DUF4749 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
PDZ | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
PDZ-LIM_domain | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
PDZ_sf | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
Zasp-like_motif | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
Znf_LIM | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
KEGG Report | rno:114108 | UniProtKB/Swiss-Prot |
MGC_CLONE | MGC:93100 | IMAGE-MGC_LOAD |
NCBI Gene | 114108 | ENTREZGENE |
PANTHER | PDZ AND LIM DOMAIN PROTEIN 3 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
PDZ AND LIM DOMAIN PROTEIN ZASP | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
Pfam | DUF4749 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
LIM | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
PDZ | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
PhenoGen | Pdlim3 | PhenoGen |
PROSITE | LIM_DOMAIN_1 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
LIM_DOMAIN_2 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
PDZ | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
RatGTEx | ENSRNOG00000012658 | RatGTEx |
SMART | LIM | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
PDZ | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
SM00735 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
Superfamily-SCOP | Glucocorticoid receptor-like (DNA-binding domain) | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL |
SSF50156 | UniProtKB/Swiss-Prot, UniProtKB/TrEMBL | |
UniProt | A0A0G2JSM3 | ENTREZGENE, UniProtKB/TrEMBL |
A0A0G2K9W2 | ENTREZGENE, UniProtKB/TrEMBL | |
A6JPQ7 | ENTREZGENE, UniProtKB/TrEMBL | |
A6JPQ8 | ENTREZGENE, UniProtKB/TrEMBL | |
D3ZFR7 | ENTREZGENE, UniProtKB/TrEMBL | |
O70208 | ENTREZGENE | |
PDLI3_RAT | UniProtKB/Swiss-Prot, ENTREZGENE | |
UniProt Secondary | O70208 | UniProtKB/Swiss-Prot |
Date | Current Symbol | Current Name | Previous Symbol | Previous Name | Description | Reference | Status |
---|---|---|---|---|---|---|---|
2004-09-10 | Pdlim3 | PDZ and LIM domain 3 | actinin alpha 2 associated LIM protein | Name updated | 1299863 | APPROVED | |
2002-08-07 | Pdlim3 | actinin alpha 2 associated LIM protein | Symbol and Name status set to provisional | 70820 | PROVISIONAL |
Note Type | Note | Reference |
---|---|---|
gene_disease | human homolog may be a candidate gene for fascioscapulohumeral muscular dystrophy | 634540 |
gene_domains | contains an NH2-terminal PDZ domain and a COOH-terminal LIM motif | |
gene_protein | 39 kDa |