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Gene: Camkk1 (calcium/calmodulin-dependent protein kinase kinase 1) Rattus norvegicus

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Symbol:

Camkk1

Name:

calcium/calmodulin-dependent protein kinase kinase 1

RGD ID:

62023

Description:

Enables calcium/calmodulin-dependent protein kinase activity and calmodulin binding activity. Involved in activation of protein kinase activity. Predicted to be located in nucleoplasm. Predicted to be active in cytoplasm. Orthologous to human CAMKK1 (calcium/calmodulin dependent protein kinase kinase 1); PARTICIPATES IN adenosine monophosphate-activated protein kinase (AMPK) signaling pathway; INTERACTS WITH 1,2,4-trimethylbenzene; 3,5-dichloro-N-[[(2S)-1-ethyl-2-pyrrolidinyl]methyl]-2-hydroxy-6-methoxybenzamide; allethrin.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

alpha CaMKK; calcium/calmodulin-dependent protein kinase kinase 1, alpha; calcium/calmodulin-dependent protein kinase kinase alpha; caM-kinase IV kinase; caM-kinase kinase 1; caM-kinase kinase alpha; caM-KK 1; caM-KK alpha; caMKK 1; caMKK alpha

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	10	58,135,872 - 58,159,023 (+)	NCBI		GRCr8
mRatBN7.2	10	57,637,335 - 57,660,498 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	10	57,637,391 - 57,660,498 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	10	62,298,025 - 62,321,091 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	10	61,786,503 - 61,809,565 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	10	57,285,586 - 57,308,642 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	10	59,585,023 - 59,608,180 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	10	59,585,072 - 59,608,165 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	10	59,324,498 - 59,347,649 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	10	59,908,749 - 59,932,276 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	10	59,922,371 - 59,945,899 (+)	NCBI
Celera	10	56,761,642 - 56,784,794 (+)	NCBI		Celera
Cytogenetic Map	10	q24	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Canavan disease (ISO)

nervous system disease (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2,4-trimethylbenzene (EXP)

1,2-dimethylhydrazine (ISO)

17beta-estradiol (ISO)

3,3',5,5'-tetrabromobisphenol A (ISO)

3,5-dichloro-N-[[(2S)-1-ethyl-2-pyrrolidinyl]methyl]-2-hydroxy-6-methoxybenzamide (EXP)

acrolein (ISO)

Aflatoxin B2 alpha (ISO)

all-trans-retinoic acid (ISO)

allethrin (EXP)

alpha-pinene (ISO)

alpha-Zearalanol (EXP)

antirheumatic drug (ISO)

aristolochic acid A (ISO)

Azoxymethane (ISO)

benzo[a]pyrene (ISO)

benzo[e]pyrene (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

Butylbenzyl phthalate (ISO)

cadmium dichloride (ISO)

carbon nanotube (ISO)

choline (ISO)

cisplatin (ISO)

clozapine (EXP)

Cuprizon (EXP)

cyclosporin A (ISO)

cyhalothrin (EXP)

cypermethrin (EXP)

DDE (ISO)

desipramine (ISO)

dextran sulfate (ISO)

Dibutyl phosphate (ISO)

dibutyl phthalate (ISO)

diethyl phthalate (ISO)

diisobutyl phthalate (ISO)

diisononyl phthalate (ISO)

endosulfan (EXP)

ethanol (ISO)

fenvalerate (EXP)

folic acid (ISO)

FR900359 (ISO)

gentamycin (EXP)

haloperidol (EXP)

ketamine (EXP)

L-methionine (ISO)

lead(0) (ISO)

methapyrilene (ISO)

methoxyacetic acid (EXP)

methoxychlor (EXP)

N-methyl-4-phenylpyridinium (ISO)

naphthalenes (EXP)

ozone (ISO)

paracetamol (EXP,ISO)

perfluorohexanesulfonic acid (ISO)

perfluorooctanoic acid (EXP,ISO)

pyrethrins (EXP)

risperidone (EXP)

rotenone (ISO)

sodium arsenite (ISO)

sodium fluoride (ISO)

Soman (EXP)

sunitinib (ISO)

thioacetamide (EXP)

thiram (ISO)

titanium dioxide (EXP,ISO)

triphenyl phosphate (ISO)

triptonide (ISO)

undecane (EXP)

valproic acid (ISO)

vinclozolin (EXP)

vincristine (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

activation of protein kinase activity (IDA)

intracellular signal transduction (IBA)

positive regulation of protein kinase activity (IDA)

protein phosphorylation (TAS)

Cellular Component

cytoplasm (IBA)

nucleoplasm (TAS)

Molecular Function

ATP binding (IEA)

calcium/calmodulin-dependent protein kinase activity (IBA,IDA,TAS)

calmodulin binding (IBA,IDA)

protein binding (ISO)

protein serine kinase activity (IEA)

protein serine/threonine kinase activity (IEA)

Molecular Pathway Annotations Click to see Annotation Detail View

adenosine monophosphate-activated protein kinase (AMPK) signaling pathway (IDA)

References

References - curated

#	Reference Title	Reference Citation
1.	Inhibition of calcium/calmodulin-dependent protein kinase kinase by protein 14-3-3.	Davare MA, etal., J Biol Chem. 2004 Dec 10;279(50):52191-9. Epub 2004 Oct 6.
2.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3.	Calmodulin-dependent protein kinase kinase-beta is an alternative upstream kinase for AMP-activated protein kinase.	Hawley SA, etal., Cell Metab. 2005 Jul;2(1):9-19.
4.	14-3-3 Proteins directly regulate Ca(2+)/calmodulin-dependent protein kinase kinase alpha through phosphorylation-dependent multisite binding.	Ichimura T, etal., FEBS Lett. 2008 Mar 5;582(5):661-5. doi: 10.1016/j.febslet.2008.01.037. Epub 2008 Jan 31.
5.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
6.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
7.	Evidence for the existence of Ca2+/calmodulin-dependent protein kinase IV kinase isoforms in rat brain.	Okuno S, etal., J Biochem (Tokyo) 1996 Jun;119(6):1176-81.
8.	GOA pipeline	RGD automated data pipeline
9.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
10.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
11.	Differential regulatory mechanism of Ca2+/calmodulin-dependent protein kinase kinase isoforms.	Tokumitsu H, etal., Biochemistry 2001 Nov 20;40(46):13925-32.
12.	Characterization of a Ca2+/calmodulin-dependent protein kinase cascade. Molecular cloning and expression of calcium/calmodulin-dependent protein kinase kinase.	Tokumitsu H, etal., J Biol Chem 1995 Aug 18;270(33):19320-4.

Additional References at PubMed

PMID:8631893	PMID:8929978	PMID:9195898	PMID:9335539	PMID:9859994	PMID:10187789	PMID:10336483	PMID:10467092	PMID:10651863	PMID:15147908	PMID:15150258	PMID:15262966
PMID:15308608	PMID:15831494	PMID:16054096	PMID:18710651	PMID:19292454	PMID:26050738	PMID:27151216	PMID:30053369	PMID:33197510	PMID:34875535

Genomics

Comparative Map Data

Camkk1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	10	58,135,872 - 58,159,023 (+)	NCBI		GRCr8
mRatBN7.2	10	57,637,335 - 57,660,498 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	10	57,637,391 - 57,660,498 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	10	62,298,025 - 62,321,091 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	10	61,786,503 - 61,809,565 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	10	57,285,586 - 57,308,642 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	10	59,585,023 - 59,608,180 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	10	59,585,072 - 59,608,165 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	10	59,324,498 - 59,347,649 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	10	59,908,749 - 59,932,276 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	10	59,922,371 - 59,945,899 (+)	NCBI
Celera	10	56,761,642 - 56,784,794 (+)	NCBI		Celera
Cytogenetic Map	10	q24	NCBI

CAMKK1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	17	3,860,315 - 3,893,053 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	17	3,860,315 - 3,894,891 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	17	3,763,609 - 3,796,347 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	17	3,710,358 - 3,743,086 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	17	3,710,366 - 3,743,086	NCBI
Celera	17	3,775,420 - 3,808,149 (-)	NCBI		Celera
Cytogenetic Map	17	p13.2	NCBI
HuRef	17	3,653,743 - 3,686,358 (-)	NCBI		HuRef
CHM1_1	17	3,771,851 - 3,805,088 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	17	3,748,985 - 3,781,678 (-)	NCBI		T2T-CHM13v2.0

Camkk1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	11	72,906,869 - 72,932,899 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	11	72,909,834 - 72,932,899 (+)	Ensembl		GRCm39 Ensembl
GRCm38	11	73,016,043 - 73,042,073 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	11	73,019,008 - 73,042,073 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	11	72,832,510 - 72,855,575 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	11	72,835,248 - 72,858,268 (+)	NCBI		MGSCv36	mm8
Celera	11	80,547,860 - 80,571,059 (+)	NCBI		Celera
Cytogenetic Map	11	B4	NCBI
cM Map	11	45.12	NCBI

Camkk1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955467	12,976,000 - 13,002,159 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955467	12,973,667 - 13,002,098 (+)	NCBI	ChiLan1.0	ChiLan1.0

CAMKK1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	19	11,470,419 - 11,502,545 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	17	13,434,426 - 13,466,545 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	17	3,908,598 - 3,941,118 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	17	3,900,441 - 3,930,061 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	17	3,900,458 - 3,930,010 (-)	Ensembl	panpan1.1		panPan2

CAMKK1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	9	47,643,781 - 47,670,536 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	9	47,645,815 - 47,663,855 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	9	46,805,691 - 46,832,442 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	9	48,488,782 - 48,515,740 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	9	48,488,787 - 48,516,079 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	9	47,266,332 - 47,293,082 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	9	47,555,150 - 47,582,105 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	9	47,611,601 - 47,638,362 (-)	NCBI		UU_Cfam_GSD_1.0

Camkk1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405602	55,374,431 - 55,399,959 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936677	499,034 - 526,594 (-)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936677	499,897 - 526,537 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

CAMKK1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	12	49,922,855 - 49,950,605 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	12	49,922,837 - 49,950,668 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	12	52,043,981 - 52,063,677 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

CAMKK1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	16	3,341,236 - 3,374,728 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	16	3,341,243 - 3,366,741 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666059	18,339,468 - 18,441,719 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Camkk1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624786	6,473,618 - 6,499,644 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624786	6,469,057 - 6,499,671 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Camkk1
85 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	273
Count of miRNA genes:	171
Interacting mature miRNAs:	211
Transcripts:	ENSRNOT00000025009
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
61441	Btemp1	Thermal response to stress QTL 1	4		body temperature trait (VT:0005535)	core body temperature (CMO:0001036)	10	35392457	63642539	Rat
1549846	Scl47	Serum cholesterol level QTL 47	3.6		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	10	50574707	95574707	Rat
152025229	Scl83	Serum cholesterol level QTL 83	4.33		blood cholesterol amount (VT:0000180)		10	35710580	68663659	Rat
1578779	Tcas10	Tongue tumor susceptibility QTL 10	3.12		tongue integrity trait (VT:0010553)	number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)	10	31297439	76297439	Rat
152025227	Bw195	Body weight QTL 195	5.73		body mass (VT:0001259)		10	46989699	68663659	Rat
631564	Apr3	Acute phase response QTL 3	3.9		blood interleukin-6 amount (VT:0008595)	plasma interleukin-6 level (CMO:0001927)	10	15275955	60275955	Rat
1298069	Bp168	Blood pressure QTL 168	5.5		blood pressure trait (VT:0000183)	systolic blood pressure (CMO:0000004)	10	26521957	98003205	Rat
2293669	Bmd33	Bone mineral density QTL 33	4.5	0.0001	femur strength trait (VT:0010010)	femoral neck polar moment of inertia (CMO:0001670)	10	49444551	81709989	Rat
152025224	Bw193	Body weight QTL 193	6.47		body mass (VT:0001259)		10	51663405	75085664	Rat
631552	Vetf2	Vascular elastic tissue fragility QTL 2	4.5	0.0002	aorta elastic tissue integrity trait (VT:0010556)	artery internal elastic lamina non-tumorous lesion count (CMO:0001913)	10	41142633	86142633	Rat
631554	Bp133	Blood pressure QTL 133		0.005	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	10	743364	63851208	Rat
631557	Bp136	Blood pressure QTL 136		0.003	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	10	30632053	75632053	Rat
61325	Aia5	Adjuvant induced arthritis QTL 5		0.01	joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	23444813	104060283	Rat
1298078	Stresp5	Stress response QTL 5	2.99	0.00025	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	10	42045676	104670812	Rat
2293679	Bmd30	Bone mineral density QTL 30	3.5	0.0001	femur mineral mass (VT:0010011)	total volumetric bone mineral density (CMO:0001728)	10	49444551	81709989	Rat
1549831	Bss6	Bone structure and strength QTL 6	4		lumbar vertebra strength trait (VT:0010574)	vertebra ultimate force (CMO:0001678)	10	57576521	102576521	Rat
1578762	Toxo1	Toxoplasma gondii resistance QTL 1			brain integrity trait (VT:0010579)	percentage of study population displaying Toxoplasma gondii brain cysts at a point in time (CMO:0002028)	10	52200030	59378278	Rat
2298544	Neuinf9	Neuroinflammation QTL 9	4.6		nervous system integrity trait (VT:0010566)	spinal cord complement component 1, q subcomponent, B chain mRNA level (CMO:0002126)	10	5801990	62146030	Rat
70164	Bw21	Body weight QTL 21	4.36	0.00005	body mass (VT:0001259)	body weight (CMO:0000012)	10	53797494	98952626	Rat
61463	Bp12	Blood pressure QTL 12	6.3	0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	10	41333258	86333258	Rat
8694173	Bw149	Body weight QTL 149	4.38	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	10	44441699	89441699	Rat
2300218	Hpcl2	Hepatic cholesterol level QTL 2			liver cholesterol amount (VT:0010498)	liver cholesterol level (CMO:0001597)	10	45029650	95600334	Rat
1554317	Bmd4	Bone mineral density QTL 4	9.4	0.0001	lumbar vertebra mineral mass (VT:0010511)	volumetric bone mineral density (CMO:0001553)	10	19816042	99406971	Rat
70171	Cari1	Carrageenan-induced inflammation QTL 1	4.9	0.0005	hypodermis integrity trait (VT:0010550)	inflammatory exudate volume (CMO:0001429)	10	53797385	107211142	Rat
1598852	Anxrr19	Anxiety related response QTL 19	5.07		body movement coordination trait (VT:0005424)	number of rearing movements in an experimental apparatus (CMO:0001752)	10	18167841	63167841	Rat
1581497	Esta1	Estrogen-induced thymic atrophy QTL 1			thymus mass (VT:0004954)	thymus wet weight (CMO:0000855)	10	21329805	61345413	Rat
724527	Bp148	Blood pressure QTL 148		0.0001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	10	28453136	73453136	Rat
1358897	Stresp6	Stress response QTL 6	4.17	0.022	blood norepinephrine amount (VT:0005663)	plasma norepinephrine level (CMO:0001010)	10	35392267	64155584	Rat
1331762	Rf40	Renal function QTL 40	3.873		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal vascular resistance (CMO:0001900)	10	29299504	64155584	Rat
2300171	Bmd58	Bone mineral density QTL 58	4.9	0.0001	lumbar vertebra mineral mass (VT:0010511)	volumetric bone mineral density (CMO:0001553)	10	26944628	71944628	Rat
61354	Pia10	Pristane induced arthritis QTL 10		0.01	joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	23444813	104060283	Rat
2301967	Cm73	Cardiac mass QTL 73	4.55		heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	10	14487011	89062041	Rat
2303118	Mamtr7	Mammary tumor resistance QTL 7		0.003	mammary gland integrity trait (VT:0010552)	mammary tumor growth rate (CMO:0000344)	10	9658275	104670812	Rat
70188	BpQTLcluster1	Blood pressure QTL cluster 1	4.864		arterial blood pressure trait (VT:2000000)	pulse pressure (CMO:0000292)	1	42323132	87323132	Rat
9589030	Epfw9	Epididymal fat weight QTL 9	19.24	0.001	epididymal fat pad mass (VT:0010421)	epididymal fat pad weight to body weight ratio (CMO:0000658)	10	44441699	89441699	Rat
10402859	Bp381	Blood pressure QTL 381		0.002	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	10	27606468	72606468	Rat
2316949	Gluco60	Glucose level QTL 60	3.7		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	10	14487011	107057807	Rat
2293652	Bmd22	Bone mineral density QTL 22	4.9	0.0001	femur mineral mass (VT:0010011)	total volumetric bone mineral density (CMO:0001728)	10	49444551	81709989	Rat
70198	BpQTLcluster9	Blood pressure QTL cluster 9	2.94		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	10	42323132	87323132	Rat
1359017	Hrtrt21	Heart rate QTL 21	2.4		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	10	51772940	96772940	Rat
2306787	Ean3	Experimental allergic neuritis QTL 3	3.1		nervous system integrity trait (VT:0010566)	body weight loss (CMO:0001399)	10	53797385	66979128	Rat
6893352	Bw100	Body weight QTL 100	0.33	0.6	body mass (VT:0001259)	body weight (CMO:0000012)	1	15906665	60906665	Rat
2312672	Insul15	Insulin level QTL 15		0.01	blood insulin amount (VT:0001560)	serum insulin level (CMO:0000358)	10	57134272	102134272	Rat
724556	Pur2	Proteinuria QTL 2	5.5		urine protein amount (VT:0005160)	urine protein level (CMO:0000591)	10	22427500	90627625	Rat
8662860	Vetf10	Vascular elastic tissue fragility QTL 10			artery integrity trait (VT:0010639)	number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)	10	6154182	73453136	Rat
61387	Bp1	Blood pressure QTL 1	5.1		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	10	51770177	107211142	Rat
1354585	Eae18a	Experimental allergic encephalomyelitis QTL 18a	7.5	0.0004	nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis severity score (CMO:0001419)	10	53797385	58445852	Rat
70223	Bp57	Blood pressure QTL 57	5		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	10	1	80676123	Rat
1354587	Kidm21	Kidney mass QTL 21	3.3		kidney mass (VT:0002707)	right kidney wet weight (CMO:0000082)	10	15028513	60430477	Rat
6893350	Bw99	Body weight QTL 99	0.87	0.16	body mass (VT:0001259)	body weight (CMO:0000012)	1	15906665	60906665	Rat
2317043	Aia7	Adjuvant induced arthritis QTL 7	3.82		joint integrity trait (VT:0010548)	left rear ankle joint diameter (CMO:0002149)	10	37565079	82565079	Rat
70224	Eae3	Experimental allergic encephalomyelitis QTL 3	4.1		nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)	10	26521957	61345413	Rat
2317042	Aia20	Adjuvant induced arthritis QTL 20	3.38		joint integrity trait (VT:0010548)	right rear ankle joint diameter (CMO:0002150)	10	37565079	82565079	Rat
1331791	Cm31	Cardiac mass QTL 31	3.84606		heart mass (VT:0007028)	heart wet weight (CMO:0000069)	10	29299504	107211142	Rat
2313087	Bmd80	Bone mineral density QTL 80	3.2	0.0001	tibia mineral mass (VT:1000283)	total volumetric bone mineral density (CMO:0001728)	10	19606483	64606483	Rat
2298495	Eae23	Experimental allergic encephalomyelitis QTL 23	16.93		nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis duration (CMO:0001424)	10	55273696	60677262	Rat
70364	Bp72	Blood pressure QTL 72			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	10	51121100	96121100	Rat
631530	Tls3	T-lymphoma susceptibility QTL 3	0	0.0001	thymus integrity trait (VT:0010555)	percentage of study population developing T-cell lymphomas during a period of time (CMO:0001911)	10	51774612	95600334	Rat
1354608	Cm33	Cardiac mass QTL 33	2.8		heart left ventricle mass (VT:0007031)	heart left ventricle wet weight (CMO:0000071)	10	54809292	99809292	Rat
631535	Cm51	Cardiac mass QTL 51	3		heart mass (VT:0007028)	calculated heart weight (CMO:0000073)	10	51786282	91669536	Rat
1576319	Cia29	Collagen induced arthritis QTL 29			joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	33973921	78973921	Rat
8552805	Bw145	Body weight QTL 145	2.2		body mass (VT:0001259)	change in body weight to body weight ratio (CMO:0002216)	10	41944526	78307017	Rat
631267	Cia20	Collagen induced arthritis QTL 20	3.2		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	23444813	104060283	Rat
2293705	Bmd25	Bone mineral density QTL 25	7.1	0.0001	femur mineral mass (VT:0010011)	compact volumetric bone mineral density (CMO:0001730)	10	49444551	81709989	Rat
1576308	Schws1	Schwannoma susceptibility QTL 1		0.0041	nervous system integrity trait (VT:0010566)	percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)	10	40035094	102359817	Rat
631269	Cia22	Collagen induced arthritis QTL 22	8.9		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	40035094	104060283	Rat
631268	Cia21	Collagen induced arthritis QTL 21	3.1		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	14487011	104060283	Rat
7207811	Bmd90	Bone mineral density QTL 90	5.2		femur size trait (VT:1000369)	femoral neck cross-sectional area (CMO:0001697)	10	49444551	81709989	Rat
1576311	Pia26	Pristane induced arthritis QTL 26			joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	31224026	75632053	Rat
631270	Cia23	Collagen induced arthritis QTL 23	3.9		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	40035094	104060283	Rat
7411614	Foco18	Food consumption QTL 18		0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	10	44441699	89441699	Rat
631547	Bp87	Blood pressure QTL 87	4.5		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	10	47369470	92369470	Rat
61427	Cia16	Collagen induced arthritis QTL 16	3.2		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	6357896	96121100	Rat
2312662	Slep8	Serum leptin concentration QTL 8		0.05	blood leptin amount (VT:0005667)	serum leptin level (CMO:0000780)	10	57134272	102134272	Rat
6893342	Cm78	Cardiac mass QTL 78	0.1	0.88	heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	10	42876766	79813922	Rat
2292441	Bp308	Blood pressure QTL 308			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	10	27606468	72606468	Rat
2313055	Bw96	Body weight QTL 96	3.6	0.0001	body mass (VT:0001259)	body weight (CMO:0000012)	10	19606483	64606483	Rat
631542	Bp82	Blood pressure QTL 82	6.8		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	10	26521957	98952741	Rat
2312668	Scl65	Serum cholesterol level QTL 65		0.001	blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	10	57134272	102134272	Rat

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
9	11	49	113	91	90	59	25	59	6	218	97	93	45	60	31

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_031662	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006246799	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006246801	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008767866	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AB023658	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AC097114	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473948	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000010	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	L42810	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	S83194	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000025009 ⟹ ENSRNOP00000025009

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	10	57,637,410 - 57,660,485 (+)	Ensembl
Rnor_6.0 Ensembl	10	59,585,072 - 59,608,165 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000104077 ⟹ ENSRNOP00000076910

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	10	57,637,391 - 57,660,498 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000106120 ⟹ ENSRNOP00000091768

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	10	57,637,410 - 57,660,485 (+)	Ensembl

RefSeq Acc Id:

NM_031662 ⟹ NP_113850

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	10	58,135,935 - 58,159,010 (+)	NCBI
mRatBN7.2	10	57,637,410 - 57,660,485 (+)	NCBI
Rnor_6.0	10	59,585,092 - 59,608,167 (+)	NCBI
Rnor_5.0	10	59,324,498 - 59,347,649 (+)	NCBI
RGSC_v3.4	10	59,908,749 - 59,932,276 (+)	RGD
Celera	10	56,761,642 - 56,784,794 (+)	RGD

Sequence:

show sequence

AAGCGGGCAGGGCGGGGCGCGCCCAGCGGGAGCGAGCCCGGCGCCCACCGCAGAGACTGTCGCC
TGGTGCCTAGGTTCCCAACAGGAATATCCACGGACTGAAGTGATGGAGCGCAGTCCAGCCGTCT
GCTGCCAAGACCCTCGAGCGGAACTGGTAGAGCGGGTGGCAGCCATCAGTGTGGCCCACCTAGA
AGAGGCAGAGGAGGGCCCAGAGCCTGCCAGCAATGGTGTGGACCCCCCACCCCGGGCCAGAGCT
GCCTCTGTGATCCCTGGCAGTGCTTCAAGACCCACACCAGTGCGTCCCAGCCTCTCTGCTAGAA
AGTTCTCCCTGCAGGAAAGACCAGCGGGAAGCTGTCTAGAGGCTCAGGTTGGGCCTTACTCTAC
AGGACCTGCCAGTCACATGTCTCCTCGGGCTTGGCGGAGACCCACCATCGAGTCCCACCATGTG
GCCATCTCAGACACAGAGGACTGTGTGCAACTGAACCAGTACAAGCTGCAGAGTGAGATTGGCA
AGGGTGCCTATGGTGTGGTGAGGCTGGCCTACAATGAAAGGGAAGACAGACACTATGCAATGAA
AGTTCTTTCCAAAAAGAAGTTACTGAAGCAGTATGGCTTTCCTCGCCGTCCTCCCCCGAGAGGG
TCCCAAGCTCCTCAGGGAGGGCCAGCCAAACAGCTGCTGCCCCTGGAGCGTGTATACCAGGAGA
TTGCCATTTTAAAGAAACTGGACCACGTGAATGTAGTCAAGTTGATCGAGGTCCTGGATGATCC
TGCTGAAGACAATCTCTATTTGGTGTTTGACCTCCTGAGAAAGGGACCAGTCATGGAAGTGCCC
TGCGACAAGCCCTTCCCAGAGGAGCAAGCTCGCCTCTACCTCCGGGACATCATCCTGGGCCTCG
AGTACTTGCACTGCCAGAAGATTGTGCACAGGGACATCAAGCCGTCCAATCTGCTCCTTGGGGA
CGATGGGCACGTGAAGATCGCCGACTTTGGTGTCAGCAACCAGTTTGAGGGGAATGATGCTCAG
CTGTCCAGTACGGCAGGGACCCCAGCATTCATGGCCCCGGAGGCCATCTCTGACACCGGCCAGA
GCTTCAGTGGGAAGGCCTTGGATGTATGGGCCACTGGGGTTACACTGTATTGTTTTGTCTACGG
GAAGTGCCCATTCATTGATGAGTACATCCTGGCCCTGCACAGAAAGATCAAGAATGAGGCCGTG
GTGTTCCCTGAGGAGCCGGAGGTCAGCGAGGAACTCAAAGACCTGATCCTGAAGATGCTAGACA
AGAATCCTGAAACAAGAATTGGGGTGTCTGATATCAAGTTACACCCTTGGGTGACCAAGCATGG
AGAGGAGCCCCTCCCTTCAGAGGAGGAACACTGCAGTGTGGTAGAGGTGACTGAGGAGGAGGTG
AAGAACTCAGTCAAGCTCATCCCCAGCTGGACCACTGTGATCCTGGTCAAGTCTATGCTGAGAA
AGCGTTCCTTTGGAAACCCATTTGAGCCCCAAGCACGCAGGGAAGAAAGATCTATGTCTGCGCC
AGGAAACTTACTGTTGAAAGAAGGATGTGGAGAAGGGGGCAAAAGCCCAGAGCTTCCCGGAGTC
CAGGAAGATGAGGCTGCATCCTGAGTCCCTGCATGTGCCCAGGGCCATCGGCAGCATGCTCATT
CCGCTCCTCCAGAGGCCCACCGCCCTCATGCAATCATCGCCCCTGCAGGCAGGGGGCTGGGGAC
TGCAGCCCCTCTCCTGGCCCCCCTCACCCATTGTGCTGCATGACCTGCGCACAGGCATATCCAG
GGACAGGATTGGAATGTGTATCATTTGGGGCTCGGGGGTCCCGGTTGGTTCTCTCTGTTCTGAT
CTATCTTGTGGGGAATATTAGAAACCCTACCTGACTGGCTGGTGAGGCCCAGGGCAGAAGGCAA
GAGACCAAAATAGCAGGTGGAGACCTGGTGGGCTGCTTCTCAGAGAACTCCCATAGTGATCGGT
GGCCTGCCCAGCTGCTGCACACGAGGAGTGATTGTGTCACTTCTGTGTGGAAGGTGCTGAGTGC
TGGAGTCCTCAGATCTCTAGTGTGGATGCTACAAGTAATGAGGCGTGCCTGGGAGAAGACTGAT
CTTGGAGAATCCAGATTCCTCTCATTGTCTTTTACCTGAGGGCTTGGGTGGGAGCGGCTGTTAT
GGAGAGCATCTTCTGGCTTTGGGTAGTCCGTGGTACACTGTACGGCAGTCACGAGGATCTGACA
TTCATAGACTGTGTTTTACACTTGGCACTCGCTGGAGAAAGGACCAAAGTGAATCCAGCTTAGA
GCATAGACCTGAGCCTGGAGCAGTGTACTTCTCCTGCCAACCTCCCTTCCTCTCTCACGGATCT
CCAGAATGAAGGTTACAGAACACCAGGAGTGACAAGGAGGGCCACGGACTCTCAGCACTGTGGC
CCTGCAGATGTGGAAGTAACTGGGATCTAGGCGCTGAGCCGACACTGGCTTACTCACTACATGC
TCTGATGGAGGAGGCTCAGCCAGATGAGGGACCGTACAAGACGCACTCCTGTCAGGCTGGTGGC
CCTTCTGTCAGTTGCTTCAGTACAGGACATCAGACAGTCAGCCCACACAGGTCAGAGCTGCACA
GTTGGGACACACGTGGACACTGCCCTTTCAGAACAGATGTCAGCTCTCTGGATTCTGTGGTCGT
CTGGCTATTCTAATGTTTACTGATAATGCTCATAGGGATTGGTCCCCAAAGGGAGATGAGCAGG
ACTCAGGTAGCCCTCTCTGAAAGCCTCCCATAAGAGATCCTGGCTGCCCACATGGGTTTCAAGA
ATGCAGGAGGGCTAGGCTAGAAAAGAGAGAGGCTGTGCGGGAGCGCTGGTTCCCACTCTTATCT
CTGTGCCCATGGGTGTACATTGCTCCTTCATGTGCACATGCGTGTGTGTGCCCATCTGCTGTAT
ACAGCACACTTGCATGTCTCATACTGGCACATGCATCTGTAATATAGTTTCTATGTCAACTTAT
GCCTAGGAGCAGAAGGTAGCCCATTGTCAAAGGGCTCCCATTTCAACCCAACTCCTCTGCACTA
AGGCAGCCAGTGTAACCCAGGGCTTGAAAACAAATAATCTAATCCTATCTCTAAGAATACTTTT
ATAGAGTGAATAGGAGGCAAGTTATGCCAACCAATAAATAGCAAAGAGTCAGGGAGCTTCACCG
ATGGGACCCACACAGGAAAAGCTCGGAGTTGGGTGGCTGGCTCATTGTCCCCAGCAGAGCCAGG
AAGGCATGCTCACTGTCACCTGTTGTTGAGAGCTTTGGTTGGCTTTGGTTTTGAATGTAGCACA
AGTGAACAAACTCCATAAGAGTGTTTATAAAAATTAACTTCTTAGGAAGTGAATTAAAAACAAT
AAAAGCCCTTTGTTGAGTT

hide sequence

RefSeq Acc Id:

XM_006246799 ⟹ XP_006246861

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	10	58,135,872 - 58,159,023 (+)	NCBI
mRatBN7.2	10	57,637,335 - 57,660,498 (+)	NCBI
Rnor_6.0	10	59,585,023 - 59,608,180 (+)	NCBI
Rnor_5.0	10	59,324,498 - 59,347,649 (+)	NCBI

Sequence:

show sequence

GGGCGGGGGAGCGAGCGCAGCCTGGAGCTGCGGCGCCAGCGGGTTGAGCCGGGCGATCCTAGCC
CGGCGAAGCGGGCAGGGCGGGGCGCGCCTAGCGGGAGCGAGCCCGGCGCCCACCGCAGAGACTG
TCGCCTGGTGCCTAGCTGCTGTCCGCGGGACTGCATAGGAACCCCTCGCGGTGCCTCGGGCCCC
GGCTCTGGGTGGAGGCCGTGTCTATTCGGAGTGGGCCTGGACGGGTACACCCACGTGTGGATCT
CGGCGGAGCGCTTCTCCCACGGCCCTCCCGTTCCCAACAGGAATATCCACGGACTGAAGTGATG
GAGCGCAGTCCAGCCGTCTGCTGCCAAGACCCTCGAGCGGAACTGGTAGAGCGGGTGGCAGCCA
TCAGTGTGGCCCACCTAGAAGAGGCAGAGGAGGGCCCAGAGCCTGCCAGCAATGGTGTGGACCC
CTCACCCCGGGCCAGAGCTGCCTCTGTGATCCCTGGCAGTGCTTCAAGACCCACACCAGTGCGT
CCCAGCCTCTCTGCTAGAAAGTTCTCCCTGCAGGAAAGACCAGCGGGAAGCTGTCTAGAGGCTC
AGGTTGGGCCTTACTCTACAGGACCTGCCAGTCACATGTCTCCTCGGGCTTGGCGGAGACCCAC
CATCGAGTCCCACCATGTGGCCATCTCAGACACAGAGGACTGTGTGCAACTGAACCAGTACAAG
CTGCAGAGTGAGATTGGCAAGGGTGCCTATGGTGTGGTGAGGCTGGCCTACAATGAAAGGGAAG
ACAGACACTATGCAATGAAAGTTCTTTCCAAAAAGAAGTTACTGAAGCAGTATGGCTTTCCTCG
CCGTCCTCCCCCGAGAGGGTCCCAAGCTCCTCAGGGAGGGCCAGCCAAACAGCTGCTGCCCCTG
GAGCGTGTATACCAGGAGATTGCCATTTTAAAGAAACTGGACCACGTGAATGTAGTCAAGTTGA
TCGAGGTCCTGGATGATCCTGCTGAAGACAATCTCTATTTGGTGTTTGACCTCCTGAGAAAGGG
ACCAGTCATGGAAGTGCCCTGCGACAAGCCCTTCCCAGAGGAGCAAGCTCGCCTCTACCTCCGG
GACATCATCCTGGGCCTCGAGTACTTGCACTGCCAGAAGATTGTGCACAGGGACATCAAGCCGT
CCAATCTGCTCCTTGGGGACGATGGGCACGTGAAGATCGCCGACTTTGGTGTCAGCAACCAGTT
TGAGGGGAATGATGCTCAGCTGTCCAGTACGGCAGGGACCCCAGCATTCATGGCCCCGGAGGCC
ATTTCTGACACCGGCCAGAGCTTCAGTGGGAAGGCCTTGGATGTATGGGCCACTGGGGTTACAC
TGTATTGTTTTGTCTACGGGAAGTGCCCATTCATTGATGAGTACATCCTGGCCCTGCACAGAAA
GATCAAGAATGAGGCCGTGGTGTTCCCTGAGGAGCCGGAGGTCAGCGAGGAACTCAAAGACCTG
ATCCTGAAGATGCTAGACAAGAATCCTGAAACAAGAATTGGGGTGTCTGATATCAAGTTACACC
CTTGGGTGACCAAGCATGGAGAGGAGCCCCTCCCTTCAGAGGAGGAACACTGCAGTGTGGTAGA
GGTGACTGAGGAGGAGGTGAAGAACTCAGTCAAGCTCATCCCCAGCTGGACCACTGTGATCCTG
GTCAAGTCTATGCTGAGAAAGCGTTCCTTTGGAAACCCATTTGAGCCCCAAGCACGCAGGGAAG
AAAGATCTATGTCTGCGCCAGGAAACTTACTGTTGAAAGAAGGATGTGGAGAAGGGGGCAAAAG
CCCAGAGCTTCCCGGAGTCCAGGAAGATGAGGCTGCATCCTGAGTCCCTGCATGTGCCCAGGGC
CATCGGCAGCATGCTCATTCCGCTCCTCCAGAGGCCCACCGCCCTCATGCAATCATCGCCCCTG
CAGGCAGGGGGCTGGGGACTGCAGCCCCTCTCCTGGCCCCCCTCACCCATTGTGCTGCATGACC
TGCGCACAGGCATATCCAGGGACAGGATTGGAATGTGTATCATTTGGGGCTCGGGGGTCCCGGT
TGGTTCTCTCTGTTCTGATCTATCTTGTGGGGAATATTAGAAACCCTACCTGACTGGCTGGTGA
GGCCCAGGGCAGAAGGCAAGAGACCAAAATAGCAGGTGGAGACCTGGTGGGCTGCTTCTCAGAG
AACTCCCATAGTGATCGGTGGCCTGCCCAGCTGCTGCACACGAGGAGTGATTGTGTCACTTCTG
TGTGGAAGGTGCTGAGTGCTGGAGTCCTCAGATCTCTAGTGTGGATGCTACAAGTAATGAGGCG
TGCCTGGGAGAAGACTGATCTTGGAGAATCCAGATTCCTCTCATTGTCTTTTACCTGAGGGCTT
GGGTGGGAGCGGCTGTTATGGAGAGCATCTTCTGGCTTTGGGTAGTCCGTGGTACACTGTACGG
CAGTCACGAGGATCTGACATTCATAGACTGTGTTTTACACTTGGCACTTGCTGGAGAAAGGACC
AAAGTGAATCCAGCTTAGAGCATAGACCTGAGCCTGGAGCAGTGTACTTCTCCTGCCAACCTCC
CTTCCTCTCTCACGGATCTCCAGAATGAAGGTTACAGAACACCAGGAGTGACAAGGAGGGCCAC
GGACTCTCAGCACTGTGGCCCTGCAGATGTGGAAGTAACTGGGATCTAGGCGCTGAGCCGACAC
TGGCTTACTCACTACATGCTCTGATGGAGGAGGCTCAGCCAGATGAGGGACCGTACAAGACGCA
CTCCTGTCAGGCTGGTGGCCCTTCTGTCAGTTGCTTCAGTACAGGACATCAGACAGTCAGCCCA
CACAGGTCAGAGCTGCACAGTTGGGACACACGTGGACACTGCCCTTTCAGAACAGATGTCAGCT
CTCTGGATTCTGTGGTCGTCTGGCTATTCTAATGTTTACTGATAATGCTCATAGGGATTGGTCC
CCAAAGGGAGATGAGCAGGACTCAGGTAGCCCTCTCTGAAAGCCTCCCATAAGAGATCCTGGCT
GCCCACATGGGTTTCAAGAATGCAGGAGGGCTAGGCTAGAAAAGAGAGAGGCTGTGCGGGAGCG
CTGGTTCCCACTCTTATCTCTGTGCCCATGGGTGTACATTGCTCCTTCATGTGCACATGCGTGT
GTGTGCCCATCTGCTGTATACAGCACACTTGCATGTCTCATACTGGCACATGCATCTGTAATAT
AGTTTCTATGTCAACTTATGCCTAGGAGCAGAAGGTAGCCCATTGTCAAAGGGCTCCCATTTCA
ACCCAACTCCTCTGCACTAAGGCAGCCAGTGTAACCCAGGGCTTGAAAACAAATAATCTAATCC
TATCTCTAAGAATACTTTTATAGAGTGAATAGGAGGCAAGTTATGCCAACCAATAAATAGCAAA
GAGTCAGGGAGCTTCACCGATGGGACCCACACAGGAAAAGCTCGGAGTTGGGTGGCTGGCTCAT
TGTCCCCAGCAGAGCCAGGAAGGCATGCTCACTGTCACCTGTTGTTGAGAGCTTTGGTTGGCTT
TGGTTTTGAATGTAGCACAAGTGAACAAACTCCATAAGAGTGTTTATAAAAATTAACTTCTTAG
GAAGTGAATTAAAAACAATAAAAGCCCTTTGTTGAGTTAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_006246801 ⟹ XP_006246863

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	10	58,135,910 - 58,159,023 (+)	NCBI
mRatBN7.2	10	57,637,357 - 57,660,498 (+)	NCBI
Rnor_6.0	10	59,585,023 - 59,608,180 (+)	NCBI
Rnor_5.0	10	59,324,498 - 59,347,649 (+)	NCBI

Sequence:

show sequence

GGGCGGGGGAGCGAGCGCAGCCTGGAGCTGCGGCGCCAGCGGGTTGAGCCGGGCGATCCTAGCC
CGGCGAAGCGGGCAGGGCGGGGCGCGCCTAGCGGGAGCGAGCCCGGCGCCCACCGCAGAGACTG
TCGCCTGGTGCCTAGGACGCTGAGGGCATGCTGCAGAGCTACGTGAGCTACTGGGGATCCCTAG
GCTTGGGTGCTGGCAAGCCAGGCCAAGGAGCAGCCGGGAGGTTCCCAACAGGAATATCCACGGA
CTGAAGTGATGGAGCGCAGTCCAGCCGTCTGCTGCCAAGACCCTCGAGCGGAACTGGTAGAGCG
GGTGGCAGCCATCAGTGTGGCCCACCTAGAAGAGGCAGAGGAGGGCCCAGAGCCTGCCAGCAAT
GGTGTGGACCCCTCACCCCGGGCCAGAGCTGCCTCTGTGATCCCTGGCAGTGCTTCAAGACCCA
CACCAGTGCGTCCCAGCCTCTCTGCTAGAAAGTTCTCCCTGCAGGAAAGACCAGCGGGAAGCTG
TCTAGAGGCTCAGGTTGGGCCTTACTCTACAGGACCTGCCAGTCACATGTCTCCTCGGGCTTGG
CGGAGACCCACCATCGAGTCCCACCATGTGGCCATCTCAGACACAGAGGACTGTGTGCAACTGA
ACCAGTACAAGCTGCAGAGTGAGATTGGCAAGGGTGCCTATGGTGTGGTGAGGCTGGCCTACAA
TGAAAGGGAAGACAGACACTATGCAATGAAAGTTCTTTCCAAAAAGAAGTTACTGAAGCAGTAT
GGCTTTCCTCGCCGTCCTCCCCCGAGAGGGTCCCAAGCTCCTCAGGGAGGGCCAGCCAAACAGC
TGCTGCCCCTGGAGCGTGTATACCAGGAGATTGCCATTTTAAAGAAACTGGACCACGTGAATGT
AGTCAAGTTGATCGAGGTCCTGGATGATCCTGCTGAAGACAATCTCTATTTGGTGTTTGACCTC
CTGAGAAAGGGACCAGTCATGGAAGTGCCCTGCGACAAGCCCTTCCCAGAGGAGCAAGCTCGCC
TCTACCTCCGGGACATCATCCTGGGCCTCGAGTACTTGCACTGCCAGAAGATTGTGCACAGGGA
CATCAAGCCGTCCAATCTGCTCCTTGGGGACGATGGGCACGTGAAGATCGCCGACTTTGGTGTC
AGCAACCAGTTTGAGGGGAATGATGCTCAGCTGTCCAGTACGGCAGGGACCCCAGCATTCATGG
CCCCGGAGGCCATTTCTGACACCGGCCAGAGCTTCAGTGGGAAGGCCTTGGATGTATGGGCCAC
TGGGGTTACACTGTATTGTTTTGTCTACGGGAAGTGCCCATTCATTGATGAGTACATCCTGGCC
CTGCACAGAAAGATCAAGAATGAGGCCGTGGTGTTCCCTGAGGAGCCGGAGGTCAGCGAGGAAC
TCAAAGACCTGATCCTGAAGATGCTAGACAAGAATCCTGAAACAAGAATTGGGGTGTCTGATAT
CAAGTTACACCCTTGGGTGACCAAGCATGGAGAGGAGCCCCTCCCTTCAGAGGAGGAACACTGC
AGTGTGGTAGAGGTGACTGAGGAGGAGGTGAAGAACTCAGTCAAGCTCATCCCCAGCTGGACCA
CTGTGATCCTGGTCAAGTCTATGCTGAGAAAGCGTTCCTTTGGAAACCCATTTGAGCCCCAAGC
ACGCAGGGAAGAAAGATCTATGTCTGCGCCAGGAAACTTACTGTTGAAAGAAGGATGTGGAGAA
GGGGGCAAAAGCCCAGAGCTTCCCGGAGTCCAGGAAGATGAGGCTGCATCCTGAGTCCCTGCAT
GTGCCCAGGGCCATCGGCAGCATGCTCATTCCGCTCCTCCAGAGGCCCACCGCCCTCATGCAAT
CATCGCCCCTGCAGGCAGGGGGCTGGGGACTGCAGCCCCTCTCCTGGCCCCCCTCACCCATTGT
GCTGCATGACCTGCGCACAGGCATATCCAGGGACAGGATTGGAATGTGTATCATTTGGGGCTCG
GGGGTCCCGGTTGGTTCTCTCTGTTCTGATCTATCTTGTGGGGAATATTAGAAACCCTACCTGA
CTGGCTGGTGAGGCCCAGGGCAGAAGGCAAGAGACCAAAATAGCAGGTGGAGACCTGGTGGGCT
GCTTCTCAGAGAACTCCCATAGTGATCGGTGGCCTGCCCAGCTGCTGCACACGAGGAGTGATTG
TGTCACTTCTGTGTGGAAGGTGCTGAGTGCTGGAGTCCTCAGATCTCTAGTGTGGATGCTACAA
GTAATGAGGCGTGCCTGGGAGAAGACTGATCTTGGAGAATCCAGATTCCTCTCATTGTCTTTTA
CCTGAGGGCTTGGGTGGGAGCGGCTGTTATGGAGAGCATCTTCTGGCTTTGGGTAGTCCGTGGT
ACACTGTACGGCAGTCACGAGGATCTGACATTCATAGACTGTGTTTTACACTTGGCACTTGCTG
GAGAAAGGACCAAAGTGAATCCAGCTTAGAGCATAGACCTGAGCCTGGAGCAGTGTACTTCTCC
TGCCAACCTCCCTTCCTCTCTCACGGATCTCCAGAATGAAGGTTACAGAACACCAGGAGTGACA
AGGAGGGCCACGGACTCTCAGCACTGTGGCCCTGCAGATGTGGAAGTAACTGGGATCTAGGCGC
TGAGCCGACACTGGCTTACTCACTACATGCTCTGATGGAGGAGGCTCAGCCAGATGAGGGACCG
TACAAGACGCACTCCTGTCAGGCTGGTGGCCCTTCTGTCAGTTGCTTCAGTACAGGACATCAGA
CAGTCAGCCCACACAGGTCAGAGCTGCACAGTTGGGACACACGTGGACACTGCCCTTTCAGAAC
AGATGTCAGCTCTCTGGATTCTGTGGTCGTCTGGCTATTCTAATGTTTACTGATAATGCTCATA
GGGATTGGTCCCCAAAGGGAGATGAGCAGGACTCAGGTAGCCCTCTCTGAAAGCCTCCCATAAG
AGATCCTGGCTGCCCACATGGGTTTCAAGAATGCAGGAGGGCTAGGCTAGAAAAGAGAGAGGCT
GTGCGGGAGCGCTGGTTCCCACTCTTATCTCTGTGCCCATGGGTGTACATTGCTCCTTCATGTG
CACATGCGTGTGTGTGCCCATCTGCTGTATACAGCACACTTGCATGTCTCATACTGGCACATGC
ATCTGTAATATAGTTTCTATGTCAACTTATGCCTAGGAGCAGAAGGTAGCCCATTGTCAAAGGG
CTCCCATTTCAACCCAACTCCTCTGCACTAAGGCAGCCAGTGTAACCCAGGGCTTGAAAACAAA
TAATCTAATCCTATCTCTAAGAATACTTTTATAGAGTGAATAGGAGGCAAGTTATGCCAACCAA
TAAATAGCAAAGAGTCAGGGAGCTTCACCGATGGGACCCACACAGGAAAAGCTCGGAGTTGGGT
GGCTGGCTCATTGTCCCCAGCAGAGCCAGGAAGGCATGCTCACTGTCACCTGTTGTTGAGAGCT
TTGGTTGGCTTTGGTTTTGAATGTAGCACAAGTGAACAAACTCCATAAGAGTGTTTATAAAAAT
TAACTTCTTAGGAAGTGAATTAAAAACAATAAAAGCCCTTTGTTGAGTTAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_008767866 ⟹ XP_008766088

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	10	58,135,872 - 58,159,023 (+)	NCBI
mRatBN7.2	10	57,637,335 - 57,660,498 (+)	NCBI
Rnor_6.0	10	59,585,023 - 59,608,180 (+)	NCBI

Sequence:

show sequence

GGGCGGGGGAGCGAGCGCAGCCTGGAGCTGCGGCGCCAGCGGGTTGAGCCGGGCGATCCTAGCC
CGGCGAAGCGGGCAGGGCGGGGCGCGCCTAGCGGGAGCGAGCCCGGCGCCCACCGCAGAGACTG
TCGCCTGGTGCCTAGCTGCTGTCCGCGGGACTGCATAGGAACCCCTCGCGGTGCCTCGGGCCCC
GGCTCTGGGTGGAGGCCGTGTCTATTCGGAGTGGGCCTGGACGGGTACACCCACGTGTGGATCT
CGGCGGAGCGCTTCTCCCACGGCCCTCCCGACGCTGAGGGCATGCTGCAGAGCTACGTGAGCTA
CTGGGGATCCCTAGGCTTGGGTGCTGGCAAGCCAGGCCAAGGAGCAGCCGGGAGGTTCCCAACA
GGAATATCCACGGACTGAAGTGATGGAGCGCAGTCCAGCCGTCTGCTGCCAAGACCCTCGAGCG
GAACTGGTAGAGCGGGTGGCAGCCATCAGTGTGGCCCACCTAGAAGAGGCAGAGGAGGGCCCAG
AGCCTGCCAGCAATGGTGTGGACCCCTCACCCCGGGCCAGAGCTGCCTCTGTGATCCCTGGCAG
TGCTTCAAGACCCACACCAGTGCGTCCCAGCCTCTCTGCTAGAAAGTTCTCCCTGCAGGAAAGA
CCAGCGGGAAGCTGTCTAGAGGCTCAGGTTGGGCCTTACTCTACAGGACCTGCCAGTCACATGT
CTCCTCGGGCTTGGCGGAGACCCACCATCGAGTCCCACCATGTGGCCATCTCAGACACAGAGGA
CTGTGTGCAACTGAACCAGTACAAGCTGCAGAGTGAGATTGGCAAGGGTGCCTATGGTGTGGTG
AGGCTGGCCTACAATGAAAGGGAAGACAGACACTATGCAATGAAAGTTCTTTCCAAAAAGAAGT
TACTGAAGCAGTATGGCTTTCCTCGCCGTCCTCCCCCGAGAGGGTCCCAAGCTCCTCAGGGAGG
GCCAGCCAAACAGCTGCTGCCCCTGGAGCGTGTATACCAGGAGATTGCCATTTTAAAGAAACTG
GACCACGTGAATGTAGTCAAGTTGATCGAGGTCCTGGATGATCCTGCTGAAGACAATCTCTATT
TGGTGTTTGACCTCCTGAGAAAGGGACCAGTCATGGAAGTGCCCTGCGACAAGCCCTTCCCAGA
GGAGCAAGCTCGCCTCTACCTCCGGGACATCATCCTGGGCCTCGAGTACTTGCACTGCCAGAAG
ATTGTGCACAGGGACATCAAGCCGTCCAATCTGCTCCTTGGGGACGATGGGCACGTGAAGATCG
CCGACTTTGGTGTCAGCAACCAGTTTGAGGGGAATGATGCTCAGCTGTCCAGTACGGCAGGGAC
CCCAGCATTCATGGCCCCGGAGGCCATTTCTGACACCGGCCAGAGCTTCAGTGGGAAGGCCTTG
GATGTATGGGCCACTGGGGTTACACTGTATTGTTTTGTCTACGGGAAGTGCCCATTCATTGATG
AGTACATCCTGGCCCTGCACAGAAAGATCAAGAATGAGGCCGTGGTGTTCCCTGAGGAGCCGGA
GGTCAGCGAGGAACTCAAAGACCTGATCCTGAAGATGCTAGACAAGAATCCTGAAACAAGAATT
GGGGTGTCTGATATCAAGTTACACCCTTGGGTGACCAAGCATGGAGAGGAGCCCCTCCCTTCAG
AGGAGGAACACTGCAGTGTGGTAGAGGTGACTGAGGAGGAGGTGAAGAACTCAGTCAAGCTCAT
CCCCAGCTGGACCACTGTGATCCTGGTCAAGTCTATGCTGAGAAAGCGTTCCTTTGGAAACCCA
TTTGAGCCCCAAGCACGCAGGGAAGAAAGATCTATGTCTGCGCCAGGAAACTTACTGTTGAAAG
AAGGATGTGGAGAAGGGGGCAAAAGCCCAGAGCTTCCCGGAGTCCAGGAAGATGAGGCTGCATC
CTGAGTCCCTGCATGTGCCCAGGGCCATCGGCAGCATGCTCATTCCGCTCCTCCAGAGGCCCAC
CGCCCTCATGCAATCATCGCCCCTGCAGGCAGGGGGCTGGGGACTGCAGCCCCTCTCCTGGCCC
CCCTCACCCATTGTGCTGCATGACCTGCGCACAGGCATATCCAGGGACAGGATTGGAATGTGTA
TCATTTGGGGCTCGGGGGTCCCGGTTGGTTCTCTCTGTTCTGATCTATCTTGTGGGGAATATTA
GAAACCCTACCTGACTGGCTGGTGAGGCCCAGGGCAGAAGGCAAGAGACCAAAATAGCAGGTGG
AGACCTGGTGGGCTGCTTCTCAGAGAACTCCCATAGTGATCGGTGGCCTGCCCAGCTGCTGCAC
ACGAGGAGTGATTGTGTCACTTCTGTGTGGAAGGTGCTGAGTGCTGGAGTCCTCAGATCTCTAG
TGTGGATGCTACAAGTAATGAGGCGTGCCTGGGAGAAGACTGATCTTGGAGAATCCAGATTCCT
CTCATTGTCTTTTACCTGAGGGCTTGGGTGGGAGCGGCTGTTATGGAGAGCATCTTCTGGCTTT
GGGTAGTCCGTGGTACACTGTACGGCAGTCACGAGGATCTGACATTCATAGACTGTGTTTTACA
CTTGGCACTTGCTGGAGAAAGGACCAAAGTGAATCCAGCTTAGAGCATAGACCTGAGCCTGGAG
CAGTGTACTTCTCCTGCCAACCTCCCTTCCTCTCTCACGGATCTCCAGAATGAAGGTTACAGAA
CACCAGGAGTGACAAGGAGGGCCACGGACTCTCAGCACTGTGGCCCTGCAGATGTGGAAGTAAC
TGGGATCTAGGCGCTGAGCCGACACTGGCTTACTCACTACATGCTCTGATGGAGGAGGCTCAGC
CAGATGAGGGACCGTACAAGACGCACTCCTGTCAGGCTGGTGGCCCTTCTGTCAGTTGCTTCAG
TACAGGACATCAGACAGTCAGCCCACACAGGTCAGAGCTGCACAGTTGGGACACACGTGGACAC
TGCCCTTTCAGAACAGATGTCAGCTCTCTGGATTCTGTGGTCGTCTGGCTATTCTAATGTTTAC
TGATAATGCTCATAGGGATTGGTCCCCAAAGGGAGATGAGCAGGACTCAGGTAGCCCTCTCTGA
AAGCCTCCCATAAGAGATCCTGGCTGCCCACATGGGTTTCAAGAATGCAGGAGGGCTAGGCTAG
AAAAGAGAGAGGCTGTGCGGGAGCGCTGGTTCCCACTCTTATCTCTGTGCCCATGGGTGTACAT
TGCTCCTTCATGTGCACATGCGTGTGTGTGCCCATCTGCTGTATACAGCACACTTGCATGTCTC
ATACTGGCACATGCATCTGTAATATAGTTTCTATGTCAACTTATGCCTAGGAGCAGAAGGTAGC
CCATTGTCAAAGGGCTCCCATTTCAACCCAACTCCTCTGCACTAAGGCAGCCAGTGTAACCCAG
GGCTTGAAAACAAATAATCTAATCCTATCTCTAAGAATACTTTTATAGAGTGAATAGGAGGCAA
GTTATGCCAACCAATAAATAGCAAAGAGTCAGGGAGCTTCACCGATGGGACCCACACAGGAAAA
GCTCGGAGTTGGGTGGCTGGCTCATTGTCCCCAGCAGAGCCAGGAAGGCATGCTCACTGTCACC
TGTTGTTGAGAGCTTTGGTTGGCTTTGGTTTTGAATGTAGCACAAGTGAACAAACTCCATAAGA
GTGTTTATAAAAATTAACTTCTTAGGAAGTGAATTAAAAACAATAAAAGCCCTTTGTTGAGTTA
AAAAAAAAAAAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_113850	(Get FASTA)	NCBI Sequence Viewer
	XP_006246861	(Get FASTA)	NCBI Sequence Viewer
	XP_006246863	(Get FASTA)	NCBI Sequence Viewer
	XP_008766088	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAB46910	(Get FASTA)	NCBI Sequence Viewer
	AAC42070	(Get FASTA)	NCBI Sequence Viewer
	BAA75246	(Get FASTA)	NCBI Sequence Viewer
	EDM05132	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000025009.6
	ENSRNOP00000076910.1
	ENSRNOP00000091768.1
	ENSRNOP00055039163
	ENSRNOP00060026187
	ENSRNOP00065035370
GenBank Protein	P97756	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_113850 ⟸ NM_031662

- UniProtKB:

Q64572 (UniProtKB/Swiss-Prot), Q794E3 (UniProtKB/Swiss-Prot), P97756 (UniProtKB/Swiss-Prot), A0A8I5YBZ4 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MERSPAVCCQDPRAELVERVAAISVAHLEEAEEGPEPASNGVDPPPRARAASVIPGSASRPTPV
RPSLSARKFSLQERPAGSCLEAQVGPYSTGPASHMSPRAWRRPTIESHHVAISDTEDCVQLNQY
KLQSEIGKGAYGVVRLAYNEREDRHYAMKVLSKKKLLKQYGFPRRPPPRGSQAPQGGPAKQLLP
LERVYQEIAILKKLDHVNVVKLIEVLDDPAEDNLYLVFDLLRKGPVMEVPCDKPFPEEQARLYL
RDIILGLEYLHCQKIVHRDIKPSNLLLGDDGHVKIADFGVSNQFEGNDAQLSSTAGTPAFMAPE
AISDTGQSFSGKALDVWATGVTLYCFVYGKCPFIDEYILALHRKIKNEAVVFPEEPEVSEELKD
LILKMLDKNPETRIGVSDIKLHPWVTKHGEEPLPSEEEHCSVVEVTEEEVKNSVKLIPSWTTVI
LVKSMLRKRSFGNPFEPQARREERSMSAPGNLLLKEGCGEGGKSPELPGVQEDEAAS

hide sequence

RefSeq Acc Id:	XP_006246861 ⟸ XM_006246799
- Peptide Label:	isoform X1
- UniProtKB:	A6HGH7 (UniProtKB/TrEMBL), A0A8I5YBZ4 (UniProtKB/TrEMBL)
- Sequence:	show sequence MERSPAVCCQDPRAELVERVAAISVAHLEEAEEGPEPASNGVDPSPRARAASVIPGSASRPTPV RPSLSARKFSLQERPAGSCLEAQVGPYSTGPASHMSPRAWRRPTIESHHVAISDTEDCVQLNQY KLQSEIGKGAYGVVRLAYNEREDRHYAMKVLSKKKLLKQYGFPRRPPPRGSQAPQGGPAKQLLP LERVYQEIAILKKLDHVNVVKLIEVLDDPAEDNLYLVFDLLRKGPVMEVPCDKPFPEEQARLYL RDIILGLEYLHCQKIVHRDIKPSNLLLGDDGHVKIADFGVSNQFEGNDAQLSSTAGTPAFMAPE AISDTGQSFSGKALDVWATGVTLYCFVYGKCPFIDEYILALHRKIKNEAVVFPEEPEVSEELKD LILKMLDKNPETRIGVSDIKLHPWVTKHGEEPLPSEEEHCSVVEVTEEEVKNSVKLIPSWTTVI LVKSMLRKRSFGNPFEPQARREERSMSAPGNLLLKEGCGEGGKSPELPGVQEDEAAS hide sequence

RefSeq Acc Id:	XP_006246863 ⟸ XM_006246801
- Peptide Label:	isoform X1
- UniProtKB:	A6HGH7 (UniProtKB/TrEMBL), A0A8I5YBZ4 (UniProtKB/TrEMBL)
- Sequence:	show sequence MERSPAVCCQDPRAELVERVAAISVAHLEEAEEGPEPASNGVDPSPRARAASVIPGSASRPTPV RPSLSARKFSLQERPAGSCLEAQVGPYSTGPASHMSPRAWRRPTIESHHVAISDTEDCVQLNQY KLQSEIGKGAYGVVRLAYNEREDRHYAMKVLSKKKLLKQYGFPRRPPPRGSQAPQGGPAKQLLP LERVYQEIAILKKLDHVNVVKLIEVLDDPAEDNLYLVFDLLRKGPVMEVPCDKPFPEEQARLYL RDIILGLEYLHCQKIVHRDIKPSNLLLGDDGHVKIADFGVSNQFEGNDAQLSSTAGTPAFMAPE AISDTGQSFSGKALDVWATGVTLYCFVYGKCPFIDEYILALHRKIKNEAVVFPEEPEVSEELKD LILKMLDKNPETRIGVSDIKLHPWVTKHGEEPLPSEEEHCSVVEVTEEEVKNSVKLIPSWTTVI LVKSMLRKRSFGNPFEPQARREERSMSAPGNLLLKEGCGEGGKSPELPGVQEDEAAS hide sequence

RefSeq Acc Id:	XP_008766088 ⟸ XM_008767866
- Peptide Label:	isoform X1
- UniProtKB:	A6HGH7 (UniProtKB/TrEMBL), A0A8I5YBZ4 (UniProtKB/TrEMBL)
- Sequence:	show sequence MERSPAVCCQDPRAELVERVAAISVAHLEEAEEGPEPASNGVDPSPRARAASVIPGSASRPTPV RPSLSARKFSLQERPAGSCLEAQVGPYSTGPASHMSPRAWRRPTIESHHVAISDTEDCVQLNQY KLQSEIGKGAYGVVRLAYNEREDRHYAMKVLSKKKLLKQYGFPRRPPPRGSQAPQGGPAKQLLP LERVYQEIAILKKLDHVNVVKLIEVLDDPAEDNLYLVFDLLRKGPVMEVPCDKPFPEEQARLYL RDIILGLEYLHCQKIVHRDIKPSNLLLGDDGHVKIADFGVSNQFEGNDAQLSSTAGTPAFMAPE AISDTGQSFSGKALDVWATGVTLYCFVYGKCPFIDEYILALHRKIKNEAVVFPEEPEVSEELKD LILKMLDKNPETRIGVSDIKLHPWVTKHGEEPLPSEEEHCSVVEVTEEEVKNSVKLIPSWTTVI LVKSMLRKRSFGNPFEPQARREERSMSAPGNLLLKEGCGEGGKSPELPGVQEDEAAS hide sequence

Ensembl Acc Id:

ENSRNOP00000025009 ⟸ ENSRNOT00000025009

Ensembl Acc Id:

ENSRNOP00000076910 ⟸ ENSRNOT00000104077

Ensembl Acc Id:

ENSRNOP00000091768 ⟸ ENSRNOT00000106120

Protein Domains

Protein kinase

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-P97756-F1-model_v2	AlphaFold	P97756	1-505	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13697398

Promoter ID:

EPDNEW_R7923

Type:

single initiation site

Name:

Camkk1_1

Description:

calcium/calmodulin-dependent protein kinase kinase 1

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	10	59,585,073 - 59,585,133	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:62023	AgrOrtholog
BioCyc Gene	G2FUF-24342	BioCyc
Ensembl Genes	ENSRNOG00000018242	Ensembl, UniProtKB/TrEMBL
	ENSRNOG00055027466	UniProtKB/Swiss-Prot
	ENSRNOG00060018674	UniProtKB/Swiss-Prot
	ENSRNOG00065025095	UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000025009.7	UniProtKB/TrEMBL
	ENSRNOT00000104077.1	UniProtKB/TrEMBL
	ENSRNOT00000106120.1	UniProtKB/TrEMBL
	ENSRNOT00055047594	UniProtKB/Swiss-Prot
	ENSRNOT00060032174	UniProtKB/Swiss-Prot
	ENSRNOT00065043172	UniProtKB/Swiss-Prot
Gene3D-CATH	Transferase(Phosphotransferase) domain 1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro	Kinase-like_dom_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Prot_kinase_dom	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Protein_kinase_ATP_BS	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Ser/Thr_kinase_AS	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	rno:60341	UniProtKB/Swiss-Prot
NCBI Gene	60341	ENTREZGENE
PANTHER	CALCIUM/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE 1	UniProtKB/TrEMBL, UniProtKB/Swiss-Prot
	MAP/MICROTUBULE AFFINITY-REGULATING KINASE	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	Pkinase	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Camkk1	PhenoGen
PROSITE	PROTEIN_KINASE_ATP	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PROTEIN_KINASE_DOM	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PROTEIN_KINASE_ST	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000018242	RatGTEx
	ENSRNOG00055027466	RatGTEx
	ENSRNOG00060018674	RatGTEx
	ENSRNOG00065025095	RatGTEx
SMART	S_TKc	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP	SSF56112	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	A0A8I5YBZ4	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6AEA0_RAT	UniProtKB/TrEMBL
	A6HGH7	ENTREZGENE, UniProtKB/TrEMBL
	F1LQD2_RAT	UniProtKB/TrEMBL
	KKCC1_RAT	UniProtKB/Swiss-Prot, ENTREZGENE
	Q64572	ENTREZGENE
	Q794E3	ENTREZGENE
UniProt Secondary	Q64572	UniProtKB/Swiss-Prot
	Q794E3	UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-03-15	Camkk1	calcium/calmodulin-dependent protein kinase kinase 1	Camkk1	calcium/calmodulin-dependent protein kinase kinase 1, alpha	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2002-06-10	Camkk1	calcium/calmodulin-dependent protein kinase kinase 1, alpha			Name updated	70584	APPROVED

RGD Curation Notes

Note Type	Note	Reference
gene_expression	expressed in brain, thymus, and spleen	632489

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

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Imported Disease Annotations - ClinVar

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RGD Manual Annotations