Nfic (nuclear factor I/C) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Behavioral & Substance Use Disorder Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Nfic (nuclear factor I/C) Rattus norvegicus
Analyze
Symbol: Nfic
Name: nuclear factor I/C
RGD ID: 62016
Description: Enables cis-regulatory region sequence-specific DNA binding activity. Involved in negative regulation of DNA-templated transcription. Predicted to be located in fibrillar center and nucleoplasm. Predicted to be active in nucleus. Orthologous to human NFIC (nuclear factor I C); PARTICIPATES IN forkhead class A signaling pathway; INTERACTS WITH 17beta-estradiol; 2,6-dinitrotoluene; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: nuclear factor 1 C-type; olfactory epithelium nuclear factor I-C
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr878,928,423 - 8,963,455 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl78,904,117 - 8,963,409 (+)EnsemblGRCr8
mRatBN7.278,278,210 - 8,309,936 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl78,253,361 - 8,309,936 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx711,168,300 - 11,193,900 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0713,043,786 - 13,069,386 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0710,911,186 - 10,936,791 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0711,151,941 - 11,179,544 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl711,152,038 - 11,177,664 (+)Ensemblrn6Rnor6.0
Rnor_5.0711,315,473 - 11,346,698 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.479,768,135 - 9,793,584 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera76,478,006 - 6,497,550 (+)NCBICelera
RGSC_v3.179,788,771 - 9,793,584 (+)NCBI
Cytogenetic Map7q11NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,6-dinitrotoluene  (EXP)
3,4-methylenedioxymethamphetamine  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxynon-2-enal  (ISO)
4-vinylcyclohexene dioxide  (ISO)
5-fluorouracil  (ISO)
6-propyl-2-thiouracil  (EXP)
acetaldehyde  (ISO)
acrolein  (ISO)
acrylamide  (ISO)
aflatoxin B1  (ISO)
alpha-pinene  (ISO)
amiodarone  (ISO)
ammonium chloride  (EXP)
amphetamine  (EXP)
antirheumatic drug  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
atrazine  (EXP)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[e]pyrene  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
buta-1,3-diene  (ISO)
butanal  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (EXP,ISO)
caffeine  (ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
cisplatin  (ISO)
clofibrate  (ISO)
coumarin  (ISO)
crotonaldehyde  (ISO)
Cuprizon  (EXP)
cyclosporin A  (ISO)
Dibutyl phosphate  (ISO)
dicrotophos  (ISO)
dimethylarsinic acid  (EXP)
diuron  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
elemental selenium  (ISO)
entinostat  (ISO)
ethanol  (ISO)
fenthion  (ISO)
finasteride  (EXP)
flutamide  (EXP)
folic acid  (ISO)
FR900359  (ISO)
furan  (EXP)
gentamycin  (EXP)
glycidol  (EXP)
hydrogen cyanide  (ISO)
inulin  (ISO)
isoprenaline  (ISO)
methapyrilene  (ISO)
methidathion  (ISO)
methoxychlor  (ISO)
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine  (ISO)
naphthalene  (ISO)
ozone  (ISO)
panobinostat  (ISO)
paracetamol  (EXP,ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phenobarbital  (ISO)
phenylmercury acetate  (ISO)
potassium cyanide  (ISO)
pregnenolone 16alpha-carbonitrile  (EXP)
progesterone  (ISO)
quercetin  (ISO)
SB 431542  (ISO)
selenium atom  (ISO)
sodium arsenite  (ISO)
sunitinib  (ISO)
tamoxifen  (ISO)
tert-butyl hydroperoxide  (ISO)
titanium dioxide  (ISO)
toluene  (EXP)
triphenyl phosphate  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vorinostat  (ISO)
zebularine  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
fibrillar center  (IEA,ISO)
nucleoplasm  (IEA,ISO)
nucleus  (IBA,IEA)

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Identification of NFI-binding sites and cloning of NFI-cDNAs suggest a regulatory role for NFI transcription factors in olfactory neuron gene expression. Baumeister H, etal., Brain Res Mol Brain Res 1999 Sep 8;72(1):65-79.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
5. Expression, DNA-binding specificity and transcriptional regulation of nuclear factor 1 family proteins from rat. Osada S, etal., Biochem J 1999 Aug 15;342 ( Pt 1)(21):189-98.
6. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
7. GOA pipeline RGD automated data pipeline
8. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
10. Gene expression profiles following exposure to a developmental neurotoxicant, Aroclor 1254: pathway analysis for possible mode(s) of action. Royland JE and Kodavanti PR, Toxicol Appl Pharmacol. 2008 Sep 1;231(2):179-96. Epub 2008 May 6.
11. Localization of 54 rat genes, and definition of new synteny groups conserved in the human and the rat. Szpirer C, etal., Mamm Genome 2000 Sep;11(9):729-35
Additional References at PubMed
PMID:1524678   PMID:9056636   PMID:12529411   PMID:16147868   PMID:19706729   PMID:25074584   PMID:25138274   PMID:31432308  


Genomics

Comparative Map Data
Nfic
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr878,928,423 - 8,963,455 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl78,904,117 - 8,963,409 (+)EnsemblGRCr8
mRatBN7.278,278,210 - 8,309,936 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl78,253,361 - 8,309,936 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx711,168,300 - 11,193,900 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0713,043,786 - 13,069,386 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0710,911,186 - 10,936,791 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0711,151,941 - 11,179,544 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl711,152,038 - 11,177,664 (+)Ensemblrn6Rnor6.0
Rnor_5.0711,315,473 - 11,346,698 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.479,768,135 - 9,793,584 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera76,478,006 - 6,497,550 (+)NCBICelera
RGSC_v3.179,788,771 - 9,793,584 (+)NCBI
Cytogenetic Map7q11NCBI
NFIC
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38193,359,630 - 3,469,217 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl193,314,403 - 3,469,217 (+)Ensemblhg38GRCh38
GRCh37193,359,628 - 3,469,215 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36193,310,616 - 3,414,603 (+)NCBIBuild 36Build 36hg18NCBI36
Build 34193,317,572 - 3,414,603NCBI
Celera193,296,412 - 3,400,416 (+)NCBICelera
Cytogenetic Map19p13.3NCBI
HuRef193,125,600 - 3,235,130 (+)NCBIHuRef
CHM1_1193,359,193 - 3,468,863 (+)NCBICHM1_1
T2T-CHM13v2.0193,337,764 - 3,447,373 (+)NCBIT2T-CHM13v2.0
Nfic
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391081,232,025 - 81,267,753 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1081,232,020 - 81,291,469 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381081,396,191 - 81,431,919 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1081,396,186 - 81,455,635 (-)Ensemblmm10GRCm38
MGSCv371080,858,936 - 80,889,918 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361080,799,320 - 80,830,302 (-)NCBIMGSCv36mm8
Celera1082,417,224 - 82,449,357 (-)NCBICelera
Cytogenetic Map10C1NCBI
cM Map1039.72NCBI
Nfic
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554955,095,450 - 5,139,442 (-)Ensembl
ChiLan1.0NW_0049554955,095,219 - 5,139,561 (-)NCBIChiLan1.0ChiLan1.0
NFIC
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2207,755,864 - 7,868,072 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1196,991,414 - 7,099,918 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0192,387,226 - 2,495,475 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1193,340,343 - 3,446,810 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl193,294,319 - 3,440,417 (+)EnsemblpanPan2panpan1.1
NFIC
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12055,920,614 - 55,980,307 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2055,914,855 - 56,014,907 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha2055,648,005 - 55,710,684 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02056,582,480 - 56,645,444 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2056,572,856 - 56,674,019 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12055,638,412 - 55,701,049 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02056,122,455 - 56,184,682 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02056,321,153 - 56,383,446 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Nfic
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118215,871,204 - 215,927,218 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365881,928,493 - 1,963,502 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365881,928,661 - 1,963,525 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NFIC
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl275,193,342 - 75,297,380 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1275,193,113 - 75,262,490 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2275,687,011 - 75,711,260 (+)NCBISscrofa10.2Sscrofa10.2susScr3
NFIC
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.163,128,553 - 3,232,485 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl63,135,480 - 3,227,601 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236660815,258,648 - 5,369,419 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Nfic
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248285,897,024 - 5,946,453 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248285,896,957 - 5,946,512 (-)NCBIHetGla 1.0HetGla 1.0hetGla2

Variants

.
Variants in Nfic
116 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:42
Count of miRNA genes:39
Interacting mature miRNAs:41
Transcripts:ENSRNOT00000006168
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
61410Bw19Body weight QTL 196.20.001body mass (VT:0001259)body weight (CMO:0000012)7166965846669658Rat
1300176Hrtrt10Heart rate QTL 103.19heart pumping trait (VT:2000009)heart rate (CMO:0000002)7123748937Rat
9590102Sffal5Serum free fatty acids level QTL 58.620.001blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)7721609752216097Rat
2290372Gluco33Glucose level QTL 332.71blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)7131777942Rat
1300149Cm6Cardiac mass QTL 64.09heart mass (VT:0007028)heart left ventricle weight to body weight ratio (CMO:0000530)71104117804Rat
631503Bp102Blood pressure QTL 1021.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7170952746709527Rat
634336Anxrr17Anxiety related response QTL 173.66locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)71509236116977875Rat
9590142Scort5Serum corticosterone level QTL 524.40.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)7132612984Rat
1582260Bw72Body weight QTL 723.20.0043body mass (VT:0001259)body weight (CMO:0000012)7139960528Rat
1582261Bw69Body weight QTL 693.20.0048body mass (VT:0001259)body weight (CMO:0000012)7139960528Rat
1582262Bw75Body weight QTL 7530.0038body mass (VT:0001259)body weight (CMO:0000012)7139960528Rat
2298550Neuinf6Neuroinflammation QTL 63.3nervous system integrity trait (VT:0010566)spinal cord RT1-B protein level (CMO:0002132)7129716167Rat
724560Plsm3Polydactyly-luxate syndrome (PLS) morphotypes QTL 30.0003tibia length (VT:0004357)tibia length (CMO:0000450)7134650782Rat
7411566Bw136Body weight QTL 13610.40.001body mass (VT:0001259)body weight gain (CMO:0000420)7132612984Rat

Markers in Region
BF406841  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.278,304,893 - 8,305,129 (+)MAPPERmRatBN7.2
Rnor_6.0711,174,503 - 11,174,738NCBIRnor6.0
Rnor_5.0711,341,657 - 11,341,892UniSTSRnor5.0
RGSC_v3.479,790,423 - 9,790,658UniSTSRGSC3.4
Celera76,494,389 - 6,494,624UniSTS
Cytogenetic Map7q11UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 163 91 90 59 92 59 6 356 192 11 142 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000006168   ⟹   ENSRNOP00000006168
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl78,933,117 - 8,958,736 (+)Ensembl
mRatBN7.2 Ensembl78,282,373 - 8,307,996 (+)Ensembl
Rnor_6.0 Ensembl711,152,038 - 11,177,664 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000093863   ⟹   ENSRNOP00000077960
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl78,929,079 - 8,960,490 (+)Ensembl
mRatBN7.2 Ensembl78,282,360 - 8,309,936 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000097025   ⟹   ENSRNOP00000083709
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl78,932,948 - 8,960,490 (+)Ensembl
mRatBN7.2 Ensembl78,282,360 - 8,308,854 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000103665   ⟹   ENSRNOP00000090255
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl78,929,079 - 8,960,490 (+)Ensembl
mRatBN7.2 Ensembl78,253,361 - 8,309,936 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000106995   ⟹   ENSRNOP00000082074
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl78,904,117 - 8,956,461 (+)Ensembl
mRatBN7.2 Ensembl78,288,127 - 8,304,388 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000114076   ⟹   ENSRNOP00000084268
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl78,933,106 - 8,963,409 (+)Ensembl
mRatBN7.2 Ensembl78,277,347 - 8,309,936 (+)Ensembl
RefSeq Acc Id: NM_031567   ⟹   NP_113755
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr878,933,169 - 8,958,795 (+)NCBI
mRatBN7.278,282,425 - 8,308,055 (+)NCBI
Rnor_6.0711,152,038 - 11,177,664 (+)NCBI
Rnor_5.0711,315,473 - 11,346,698 (+)NCBI
RGSC_v3.479,768,135 - 9,793,584 (+)RGD
Celera76,478,006 - 6,497,550 (+)RGD
Sequence:
RefSeq Acc Id: XM_006240850   ⟹   XP_006240912
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr878,933,045 - 8,963,455 (+)NCBI
mRatBN7.278,282,296 - 8,309,936 (+)NCBI
Rnor_6.0711,151,941 - 11,179,544 (+)NCBI
Rnor_5.0711,315,473 - 11,346,698 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039078560   ⟹   XP_038934488
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr878,928,423 - 8,963,455 (+)NCBI
mRatBN7.278,278,211 - 8,309,936 (+)NCBI
RefSeq Acc Id: XM_039078561   ⟹   XP_038934489
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr878,928,423 - 8,963,455 (+)NCBI
mRatBN7.278,278,210 - 8,309,936 (+)NCBI
RefSeq Acc Id: NP_113755   ⟸   NM_031567
- UniProtKB: O70188 (UniProtKB/TrEMBL),   A0A8I5ZTI5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006240912   ⟸   XM_006240850
- Peptide Label: isoform X3
- UniProtKB: A0A8I5ZZR6 (UniProtKB/TrEMBL),   A0A8I5ZTI5 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000006168   ⟸   ENSRNOT00000006168
RefSeq Acc Id: XP_038934489   ⟸   XM_039078561
- Peptide Label: isoform X2
- UniProtKB: A0A8I5ZTI5 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038934488   ⟸   XM_039078560
- Peptide Label: isoform X1
- UniProtKB: A0A8I5ZYT8 (UniProtKB/TrEMBL),   A0A8I6AMP4 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000077960   ⟸   ENSRNOT00000093863
Ensembl Acc Id: ENSRNOP00000090255   ⟸   ENSRNOT00000103665
Ensembl Acc Id: ENSRNOP00000082074   ⟸   ENSRNOT00000106995
Ensembl Acc Id: ENSRNOP00000083709   ⟸   ENSRNOT00000097025
Ensembl Acc Id: ENSRNOP00000084268   ⟸   ENSRNOT00000114076
Protein Domains
CTF/NF-I

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-O70188-F1-model_v2 AlphaFold O70188 1-439 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13694970
Promoter ID:EPDNEW_R5495
Type:initiation region
Name:Nfic_1
Description:nuclear factor I/C
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0711,152,009 - 11,152,069EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:62016 AgrOrtholog
BioCyc Gene G2FUF-35031 BioCyc
Ensembl Genes ENSRNOG00000004505 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000006168 ENTREZGENE
  ENSRNOT00000006168.8 UniProtKB/TrEMBL
  ENSRNOT00000093863 ENTREZGENE
  ENSRNOT00000093863.1 UniProtKB/TrEMBL
  ENSRNOT00000097025 ENTREZGENE
  ENSRNOT00000097025.1 UniProtKB/TrEMBL
  ENSRNOT00000103665 ENTREZGENE
  ENSRNOT00000103665.1 UniProtKB/TrEMBL
  ENSRNOT00000106995.1 UniProtKB/TrEMBL
  ENSRNOT00000114076.1 UniProtKB/TrEMBL
InterPro CTF/NFI UniProtKB/TrEMBL
  CTF/NFI_DNA-bd-dom UniProtKB/TrEMBL
  CTF/NFI_DNA-bd_CS UniProtKB/TrEMBL
  CTF/NFI_DNA-bd_N UniProtKB/TrEMBL
  MAD_homology1_Dwarfin-type UniProtKB/TrEMBL
KEGG Report rno:29228 UniProtKB/TrEMBL
NCBI Gene 29228 ENTREZGENE
PANTHER CTF_NFI UniProtKB/TrEMBL
  NUCLEAR FACTOR 1 C-TYPE UniProtKB/TrEMBL
Pfam CTF_NFI UniProtKB/TrEMBL
  MH1 UniProtKB/TrEMBL
  NfI_DNAbd_pre-N UniProtKB/TrEMBL
PhenoGen Nfic PhenoGen
PROSITE CTF_NFI_1 UniProtKB/TrEMBL
  CTF_NFI_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000004505 RatGTEx
SMART DWA UniProtKB/TrEMBL
UniProt A0A8I5ZTI5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZYT8 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZZR6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AMP4 ENTREZGENE, UniProtKB/TrEMBL
  A6K878_RAT UniProtKB/TrEMBL
  A6K879_RAT UniProtKB/TrEMBL
  F7EL25_RAT UniProtKB/TrEMBL
  O70188 ENTREZGENE, UniProtKB/TrEMBL
  Q9QY87_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2002-06-10 Nfic  nuclear factor I/C      Name updated 70584 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_product member of a family of olfactory epithelium transcription factors 633408