Enables interleukin-10 binding activity and interleukin-10 receptor activity. Involved in regulation of synapse organization and response to lipopolysaccharide. Predicted to be located in cytosol. Predicted to be active in apical plasma membrane. Human ortholog(s) of this gene implicated in inflammatory bowel disease 28. Orthologous to human IL10RA (interleukin 10 receptor subunit alpha); PARTICIPATES IN Interleukin-10 signaling pathway; cytokine mediated signaling pathway; Jak-Stat signaling pathway; INTERACTS WITH 17beta-estradiol; 17beta-estradiol 3-benzoate; 2,3,7,8-tetrachlorodibenzodioxine.
[Clofibrate co-treated with Acetaminophen] affects the expression of IL10RA mRNA and PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of IL10RA mRNA]
[sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in increased expression of IL10RA mRNA
(+)-JQ1 compound inhibits the reaction [Lipopolysaccharides results in increased expression of IL10RA mRNA] and clopidogrel inhibits the reaction [Lipopolysaccharides results in increased expression of IL10RA mRNA]
[sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in increased expression of IL10RA mRNA
[Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in decreased expression of IL10RA mRNA and [Air Pollutants results in increased abundance of Ozone] which results in decreased expression of IL10RA mRNA
[Clofibrate co-treated with Acetaminophen] affects the expression of IL10RA mRNA and PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of IL10RA mRNA]
[sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in increased expression of IL10RA mRNA
[sodium arsenate co-treated with sodium arsenite co-treated with monomethylarsonic acid co-treated with Cacodylic Acid] results in increased expression of IL10RA mRNA
Regional and temporal expression patterns of interleukin-10, interleukin-10 receptor and adhesion molecules in the rat spinal cord during chronic relapsing EAE.
Interleukin (IL)-10 inhibits RANTES-, tumour necrosis factor (TNF)- and nerve growth factor (NGF)-induced mast cell migratory response but is not a mast cell chemoattractant.
The rat interleukin 10 receptor: cloning and sequencing of cDNA coding for the alpha-chain protein sequence, and demonstration by western blotting of expression in the rat brain.