Zmat3 (zinc finger, matrin type 3) - Rat Genome Database

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Pathways
Gene: Zmat3 (zinc finger, matrin type 3) Rattus norvegicus
Analyze
Symbol: Zmat3
Name: zinc finger, matrin type 3
RGD ID: 620134
Description: Predicted to enable RNA binding activity and zinc ion binding activity. Involved in positive regulation of apoptotic process. Predicted to be located in nucleolus. Orthologous to human ZMAT3 (zinc finger matrin-type 3); PARTICIPATES IN p53 signaling pathway; INTERACTS WITH (+)-schisandrin B; 1-nitropropane; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: p53 target zinc finger protein; p53-activated gene 608; PAG608; Wig1; wild-type p53-induced gene 1; zinc finger matrin-type protein 3; zinc finger protein WIG-1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82117,034,517 - 117,066,141 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl2117,034,517 - 117,065,294 (-)EnsemblGRCr8
mRatBN7.22115,106,046 - 115,136,888 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2115,106,966 - 115,136,863 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx2121,720,010 - 121,750,776 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02119,832,639 - 119,863,404 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02114,533,608 - 114,564,419 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.02118,715,229 - 118,746,109 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2118,721,334 - 118,745,766 (-)Ensemblrn6Rnor6.0
Rnor_5.02138,381,017 - 138,411,897 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.42118,526,985 - 118,537,727 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera2110,217,632 - 110,248,380 (-)NCBICelera
RGSC_v3.12118,471,951 - 118,482,689 (+)NCBI
Cytogenetic Map2q24NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
(-)-demecolcine  (ISO)
1,1-dichloroethene  (ISO)
1,2-dimethylhydrazine  (ISO)
1-nitropropane  (EXP)
17alpha-ethynylestradiol  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
2,4-diaminotoluene  (EXP)
2,4-dinitrotoluene  (EXP)
2,6-diaminotoluene  (EXP)
2-acetamidofluorene  (EXP,ISO)
2-nitro-p-phenylenediamine  (EXP)
2-nitrofluorene  (EXP)
2-nitropropane  (EXP)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
3-methylcholanthrene  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one  (EXP)
4-acetylaminofluorene  (EXP)
4-hydroxynon-2-enal  (ISO)
4-hydroxyphenyl retinamide  (ISO)
4-nitro-1,2-phenylenediamine  (EXP)
5-aza-2'-deoxycytidine  (ISO)
5-fluorouracil  (ISO)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
actinomycin D  (ISO)
adefovir pivoxil  (ISO)
aflatoxin B1  (EXP,ISO)
amitrole  (EXP)
ammonium chloride  (EXP)
amphetamine  (EXP)
arsane  (ISO)
arsenic atom  (ISO)
atrazine  (ISO)
belinostat  (ISO)
benzene  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[b]fluoranthene  (ISO)
benzo[e]pyrene  (ISO)
bicalutamide  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
butan-1-ol  (ISO)
cadmium dichloride  (ISO)
camptothecin  (ISO)
carbamazepine  (ISO)
chloroacetaldehyde  (ISO)
chromium(6+)  (ISO)
chrysene  (ISO)
cidofovir anhydrous  (ISO)
cisplatin  (ISO)
cobalt dichloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
crocidolite asbestos  (ISO)
daunorubicin  (ISO)
dexamethasone  (ISO)
diazinon  (EXP)
dibenz[a,h]anthracene  (ISO)
dieldrin  (EXP)
diethylstilbestrol  (EXP)
dimethyl sulfoxide  (ISO)
dioxygen  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
entinostat  (ISO)
ethanol  (ISO)
ethyl methanesulfonate  (ISO)
etoposide  (ISO)
flavonoids  (EXP)
folic acid  (ISO)
formaldehyde  (ISO)
furan  (ISO)
gentamycin  (EXP)
ibuprofen  (ISO)
ifosfamide  (ISO)
indometacin  (ISO)
iron dichloride  (ISO)
leflunomide  (ISO)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
mercury dibromide  (ISO)
methamphetamine  (EXP,ISO)
methapyrilene  (EXP,ISO)
methimazole  (EXP)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
mitoxantrone  (ISO)
N-nitrosodiethylamine  (ISO)
N-nitrosodimethylamine  (EXP)
Nutlin-3  (ISO)
ochratoxin A  (EXP,ISO)
okadaic acid  (ISO)
paracetamol  (ISO)
phenobarbital  (EXP)
phenylmercury acetate  (ISO)
piperonyl butoxide  (EXP)
pirinixic acid  (EXP)
piroxicam  (ISO)
potassium bromate  (ISO)
potassium chromate  (ISO)
potassium dichromate  (ISO)
pregnenolone 16alpha-carbonitrile  (EXP)
quercetin  (ISO)
resveratrol  (ISO)
Salinomycin  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
sulfadimethoxine  (EXP)
sulforaphane  (ISO)
sunitinib  (ISO)
temozolomide  (ISO)
testosterone  (ISO)
tetrachloromethane  (EXP,ISO)
tetraphene  (ISO)
thapsigargin  (ISO)
thioacetamide  (EXP)
tipifarnib  (EXP)
titanium dioxide  (ISO)
trichostatin A  (ISO)
triphenyl phosphate  (ISO)
Triptolide  (ISO)
trovafloxacin  (ISO)
tunicamycin  (ISO)
urethane  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
vincristine  (ISO)
vorinostat  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. A novel p53-inducible gene, PAG608, encodes a nuclear zinc finger protein whose overexpression promotes apoptosis. Israeli D, etal., EMBO J 1997 Jul 16;16(14):4384-92.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
4. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
5. GOA pipeline RGD automated data pipeline
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12196512   PMID:17234339   PMID:18242749   PMID:22658674  


Genomics

Comparative Map Data
Zmat3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82117,034,517 - 117,066,141 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl2117,034,517 - 117,065,294 (-)EnsemblGRCr8
mRatBN7.22115,106,046 - 115,136,888 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2115,106,966 - 115,136,863 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx2121,720,010 - 121,750,776 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02119,832,639 - 119,863,404 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02114,533,608 - 114,564,419 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.02118,715,229 - 118,746,109 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2118,721,334 - 118,745,766 (-)Ensemblrn6Rnor6.0
Rnor_5.02138,381,017 - 138,411,897 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.42118,526,985 - 118,537,727 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera2110,217,632 - 110,248,380 (-)NCBICelera
RGSC_v3.12118,471,951 - 118,482,689 (+)NCBI
Cytogenetic Map2q24NCBI
ZMAT3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383179,017,223 - 179,072,513 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3178,960,121 - 179,072,323 (-)Ensemblhg38GRCh38
GRCh373178,735,011 - 178,790,301 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 363180,224,196 - 180,272,278 (-)NCBIBuild 36Build 36hg18NCBI36
Celera3177,164,280 - 177,219,033 (-)NCBICelera
Cytogenetic Map3q26.32NCBI
HuRef3176,139,723 - 176,194,425 (-)NCBIHuRef
CHM1_13178,697,897 - 178,752,559 (-)NCBICHM1_1
T2T-CHM13v2.03181,821,051 - 181,876,314 (-)NCBIT2T-CHM13v2.0
Zmat3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39332,388,941 - 32,419,814 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl332,388,941 - 32,420,163 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38332,334,792 - 32,365,665 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl332,334,792 - 32,366,014 (-)Ensemblmm10GRCm38
MGSCv37332,233,714 - 32,264,587 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36332,526,345 - 32,557,169 (-)NCBIMGSCv36mm8
Celera332,246,614 - 32,279,808 (-)NCBICelera
Cytogenetic Map3A3NCBI
cM Map315.67NCBI
Zmat3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554208,274,395 - 8,298,224 (-)Ensembl
ChiLan1.0NW_0049554208,270,026 - 8,301,313 (-)NCBIChiLan1.0ChiLan1.0
ZMAT3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22176,897,222 - 176,951,103 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13176,901,939 - 176,956,469 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03176,061,012 - 176,115,454 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13184,241,544 - 184,288,639 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3184,128,233 - 184,288,639 (-)EnsemblpanPan2panpan1.1
ZMAT3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13412,527,909 - 12,575,409 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3412,535,040 - 12,575,517 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha3416,671,301 - 16,718,806 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.03412,424,179 - 12,471,946 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3412,427,148 - 12,456,737 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13412,479,474 - 12,527,211 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03412,458,610 - 12,506,860 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03412,698,359 - 12,746,266 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Zmat3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405602109,118,097 - 109,154,057 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365664,070,693 - 4,095,868 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365664,066,683 - 4,102,643 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ZMAT3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13117,117,626 - 117,147,604 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.113117,113,272 - 117,147,639 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213126,270,158 - 126,280,510 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ZMAT3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11510,374,093 - 10,434,212 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1510,373,904 - 10,430,759 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366606319,255,951 - 19,318,869 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Zmat3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473056,821,546 - 56,849,825 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462473056,814,773 - 56,850,697 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Zmat3
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v13122,644,891 - 122,670,068 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Zmat3
151 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:438
Count of miRNA genes:251
Interacting mature miRNAs:309
Transcripts:ENSRNOT00000013858
Prediction methods:Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2293671Bss44Bone structure and strength QTL 4410.970.0001lumbar vertebra morphology trait (VT:0010494)lumbar vertebra cortical cross-sectional area (CMO:0001690)2105628029150628029Rat
1298074Bp164Blood pressure QTL 1640.003arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)244537979205135428Rat
1598865Bp296Blood pressure QTL 2962.1arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)282947902127947902Rat
1354648Bp239Blood pressure QTL 2390.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)267845370229470703Rat
1578772Stresp14Stress response QTL 1450.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)284056790132859658Rat
1354649Kidm17Kidney mass QTL 172.9kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)283465462229820014Rat
10755499Bp389Blood pressure QTL 3892.61arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)220695736231474293Rat
1581576Pur7Proteinuria QTL 70.0001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)280396178220931218Rat
152025242Bw191Body weight QTL 1913.62body mass (VT:0001259)240306867124537199Rat
631198Cm22Cardiac mass QTL 224.30.0008heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)278269809208420281Rat
1302794Stl27Serum triglyceride level QTL 274.40.0001blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)227148328145807373Rat
1581569Uae32Urinary albumin excretion QTL 320.0001urine protein amount (VT:0005160)urine albumin excretion rate (CMO:0000757)280396178220931218Rat
2317886Alcrsp23Alcohol response QTL 232.40.63response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)295142371140142371Rat
1358901Cm38Cardiac mass QTL 382heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)227148328159440891Rat
2317058Aia13Adjuvant induced arthritis QTL 132.9joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)278269809123269809Rat
1331760Bp206Blood pressure QTL 2063.62454arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)24265106205135428Rat
1358899Kidm23Kidney mass QTL 233.88kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)227148328159440891Rat
1358908Bw49Body weight QTL 493.36body mass (VT:0001259)body weight (CMO:0000012)227148557159440760Rat
1358910Kidm27Kidney mass QTL 275.77kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)227148328159440891Rat
1358911Kidm28Kidney mass QTL 285.42kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)227148328159440891Rat
1358904Cm39Cardiac mass QTL 392.26heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)227148328159440891Rat
1359035Bp276Blood pressure QTL 276arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)2100807373145807373Rat
8662836Vetf8Vascular elastic tissue fragility QTL 80.66thoracic aorta molecular composition trait (VT:0010568)aorta wall extracellular elastin dry weight to aorta wall extracellular collagen weight ratio (CMO:0002003)2106869825151869825Rat
1358887Bw50Body weight QTL 502.39body mass (VT:0001259)body weight (CMO:0000012)227148557159440760Rat
1298080Bp163Blood pressure QTL 1630.02arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)267845182205135428Rat
8662832Vetf7Vascular elastic tissue fragility QTL 73.5aorta elastin amount (VT:0003905)aorta wall extracellular elastin dry weight to aorta wall dry weight ratio (CMO:0002002)283400752223709938Rat
1298085Bp165Blood pressure QTL 1650.0006arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)244537979205135428Rat
2290453Scl55Serum cholesterol level QTL 552.83blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)228652666139067443Rat
2299162Iddm32Insulin dependent diabetes mellitus QTL 322.36blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)293602631145807373Rat
1358894Kidm24Kidney mass QTL 244.03kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)227148328159440891Rat
724534Uae6Urinary albumin excretion QTL 610urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)280396034220931416Rat
61374Edpm2Estrogen-dependent pituitary mass QTL 24.420.86pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)278269809205135428Rat
634308Sach6Saccharin preference QTL 64.9taste sensitivity trait (VT:0001986)saccharin intake volume to total fluid intake volume ratio (CMO:0001601)2114384617215381366Rat
61392Bp6Blood pressure QTL 67arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)282214549127214549Rat
1358917Cm42Cardiac mass QTL 422.82heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)227148328206613235Rat
1358913Cm41Cardiac mass QTL 412.73heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)227148328206613235Rat
1300165Rf9Renal function QTL 93.28kidney glomerulus integrity trait (VT:0010546)index of glomerular damage (CMO:0001135)2113746222205135428Rat
7488933Bp368Blood pressure QTL 3680.004arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2104957381149957381Rat
631507Bp105Blood pressure QTL 1050.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2114384617215381366Rat
2293835Kiddil5Kidney dilation QTL 53.8kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)244537979159440891Rat
1581552Pur12Proteinuria QTL 125.190.0009urine total protein amount (VT:0000032)urine protein excretion rate (CMO:0000759)2114032149150226270Rat
1354622Kidm16Kidney mass QTL 163kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)283465462225110681Rat
1558653Prcr1Prostate cancer resistance QTL 15prostate integrity trait (VT:0010571)area of ventral prostate occupied by tumorous lesions to total ventral prostate area ratio (CMO:0000899)2114440891159440891Rat
631266Bp132Blood pressure QTL 1320.0005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)247856345205135428Rat
2293843Kiddil6Kidney dilation QTL 63.1kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)244537979184731399Rat
1354594Despr10Despair related QTL 102e-06locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)2116804572161804572Rat
152025206Hrtrt23Heart rate QTL 235.98heart pumping trait (VT:2000009)230219200171802126Rat
1354605Rf48Renal function QTL 482.9blood creatinine amount (VT:0005328)plasma creatinine level (CMO:0000537)276328396209350714Rat
152025204Hrtrt22Heart rate QTL 225.6heart pumping trait (VT:2000009)230219200171802126Rat
61438Cia7Collagen induced arthritis QTL 74.60.0001joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)261051541143746880Rat

Markers in Region
D2Wox57  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22115,111,296 - 115,111,453 (+)MAPPERmRatBN7.2
Rnor_6.02118,720,476 - 118,720,632NCBIRnor6.0
Rnor_5.02138,386,264 - 138,386,420UniSTSRnor5.0
RGSC_v3.42118,532,324 - 118,532,480UniSTSRGSC3.4
Celera2110,222,879 - 110,223,035UniSTS
Cytogenetic Map2q25UniSTS
D1S2831  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21343,424,093 - 43,424,474 (+)MAPPERmRatBN7.2
mRatBN7.22115,113,244 - 115,113,795 (+)MAPPERmRatBN7.2
Rnor_6.02118,722,424 - 118,722,974NCBIRnor6.0
Rnor_6.01348,762,789 - 48,763,169NCBIRnor6.0
Rnor_5.02138,388,212 - 138,388,762UniSTSRnor5.0
Rnor_5.01353,833,597 - 53,833,977UniSTSRnor5.0
RGSC_v3.41344,857,679 - 44,858,059UniSTSRGSC3.4
Celera1343,760,802 - 43,761,180UniSTS
Celera2110,224,827 - 110,225,377UniSTS
Cytogenetic Map2q25UniSTS
Cytogenetic Map13q13UniSTS
RH133757  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22115,108,117 - 115,108,300 (+)MAPPERmRatBN7.2
Rnor_6.02118,717,297 - 118,717,479NCBIRnor6.0
Rnor_5.02138,383,085 - 138,383,267UniSTSRnor5.0
RGSC_v3.42118,535,477 - 118,535,659UniSTSRGSC3.4
Celera2110,219,700 - 110,219,882UniSTS
RH 3.4 Map2692.6UniSTS
Cytogenetic Map2q25UniSTS
AI101844  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22115,108,840 - 115,109,026 (+)MAPPERmRatBN7.2
Rnor_6.02118,718,020 - 118,718,205NCBIRnor6.0
Rnor_5.02138,383,808 - 138,383,993UniSTSRnor5.0
RGSC_v3.42118,534,751 - 118,534,936UniSTSRGSC3.4
Celera2110,220,423 - 110,220,608UniSTS
RH 3.4 Map2688.7UniSTS
Cytogenetic Map2q25UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 163 91 90 59 91 59 6 355 191 11 142 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000013858   ⟹   ENSRNOP00000013858
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2115,111,153 - 115,136,606 (-)Ensembl
Rnor_6.0 Ensembl2118,721,334 - 118,745,766 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000103680   ⟹   ENSRNOP00000087283
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl2117,034,517 - 117,065,294 (-)Ensembl
mRatBN7.2 Ensembl2115,106,966 - 115,132,570 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000113458   ⟹   ENSRNOP00000083964
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl2115,106,966 - 115,136,863 (-)Ensembl
RefSeq Acc Id: NM_022548   ⟹   NP_071993
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82117,034,517 - 117,065,294 (-)NCBI
mRatBN7.22115,106,046 - 115,136,888 (-)NCBI
Rnor_6.02118,715,229 - 118,746,109 (-)NCBI
Rnor_5.02138,381,017 - 138,411,897 (-)NCBI
RGSC_v3.42118,526,985 - 118,537,727 (+)RGD
Celera2110,217,632 - 110,248,380 (-)RGD
Sequence:
RefSeq Acc Id: XM_063282482   ⟹   XP_063138552
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82117,034,517 - 117,066,141 (-)NCBI
RefSeq Acc Id: XM_063282483   ⟹   XP_063138553
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82117,034,517 - 117,066,141 (-)NCBI
RefSeq Acc Id: XM_063282484   ⟹   XP_063138554
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82117,034,517 - 117,063,672 (-)NCBI
RefSeq Acc Id: XM_063282485   ⟹   XP_063138555
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82117,034,517 - 117,066,141 (-)NCBI
RefSeq Acc Id: XM_063282486   ⟹   XP_063138556
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82117,034,517 - 117,064,775 (-)NCBI
RefSeq Acc Id: XM_063282487   ⟹   XP_063138557
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82117,034,517 - 117,063,656 (-)NCBI
RefSeq Acc Id: XM_063282488   ⟹   XP_063138558
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82117,034,517 - 117,064,763 (-)NCBI
RefSeq Acc Id: XM_063282489   ⟹   XP_063138559
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82117,034,517 - 117,064,776 (-)NCBI
RefSeq Acc Id: XM_063282490   ⟹   XP_063138560
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82117,043,086 - 117,066,141 (-)NCBI
RefSeq Acc Id: NP_071993   ⟸   NM_022548
- UniProtKB: O08781 (UniProtKB/Swiss-Prot),   A6IHN5 (UniProtKB/TrEMBL),   A0A8I6GFU9 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000013858   ⟸   ENSRNOT00000013858
Ensembl Acc Id: ENSRNOP00000083964   ⟸   ENSRNOT00000113458
Ensembl Acc Id: ENSRNOP00000087283   ⟸   ENSRNOT00000103680
RefSeq Acc Id: XP_063138552   ⟸   XM_063282482
- Peptide Label: isoform X1
- UniProtKB: A0A8L2Q6J0 (UniProtKB/TrEMBL),   A0A8I6GFU9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063138555   ⟸   XM_063282485
- Peptide Label: isoform X2
- UniProtKB: O08781 (UniProtKB/Swiss-Prot),   A6IHN5 (UniProtKB/TrEMBL),   A0A8I6GFU9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063138553   ⟸   XM_063282483
- Peptide Label: isoform X1
- UniProtKB: A0A8L2Q6J0 (UniProtKB/TrEMBL),   A0A8I6GFU9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063138559   ⟸   XM_063282489
- Peptide Label: isoform X2
- UniProtKB: O08781 (UniProtKB/Swiss-Prot),   A6IHN5 (UniProtKB/TrEMBL),   A0A8I6GFU9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063138556   ⟸   XM_063282486
- Peptide Label: isoform X1
- UniProtKB: A0A8L2Q6J0 (UniProtKB/TrEMBL),   A0A8I6GFU9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063138558   ⟸   XM_063282488
- Peptide Label: isoform X2
- UniProtKB: O08781 (UniProtKB/Swiss-Prot),   A6IHN5 (UniProtKB/TrEMBL),   A0A8I6GFU9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063138554   ⟸   XM_063282484
- Peptide Label: isoform X1
- UniProtKB: A0A8L2Q6J0 (UniProtKB/TrEMBL),   A0A8I6GFU9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063138557   ⟸   XM_063282487
- Peptide Label: isoform X2
- UniProtKB: O08781 (UniProtKB/Swiss-Prot),   A6IHN5 (UniProtKB/TrEMBL),   A0A8I6GFU9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063138560   ⟸   XM_063282490
- Peptide Label: isoform X3
Protein Domains
C2H2-type   U1-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-O08781-F1-model_v2 AlphaFold O08781 1-289 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:620134 AgrOrtholog
BioCyc Gene G2FUF-53433 BioCyc
Ensembl Genes ENSRNOG00000010119 Ensembl
  ENSRNOG00000063864 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000103680 ENTREZGENE
  ENSRNOT00000113458.1 UniProtKB/Swiss-Prot
Gene3D-CATH Classic Zinc Finger UniProtKB/Swiss-Prot
InterPro Matrin/U1-like-C_Znf_C2H2 UniProtKB/Swiss-Prot
  ZMAT3 UniProtKB/Swiss-Prot
  Znf_C2H2_jaz UniProtKB/Swiss-Prot
  Znf_C2H2_sf UniProtKB/Swiss-Prot
  Znf_C2H2_type UniProtKB/Swiss-Prot
KEGG Report rno:64394 UniProtKB/Swiss-Prot
NCBI Gene 64394 ENTREZGENE
PANTHER ZINC FINGER MATRIN-TYPE PROTEIN 3 UniProtKB/Swiss-Prot
  ZINC FINGER MATRIN-TYPE PROTEIN 3 UniProtKB/Swiss-Prot
Pfam zf-C2H2_jaz UniProtKB/Swiss-Prot
  zf-met UniProtKB/Swiss-Prot
PhenoGen Zmat3 PhenoGen
RatGTEx ENSRNOG00000010119 RatGTEx
  ENSRNOG00000063864 RatGTEx
SMART ZnF_C2H2 UniProtKB/Swiss-Prot
  ZnF_U1 UniProtKB/Swiss-Prot
Superfamily-SCOP SSF57667 UniProtKB/Swiss-Prot
UniProt A0A8I6GFU9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8L2Q6J0 ENTREZGENE
  A6IHN5 ENTREZGENE, UniProtKB/TrEMBL
  O08781 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-02-19 Zmat3  zinc finger, matrin type 3  Wig1  wild-type p53-induced gene 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-09-10 Wig1  wild-type p53-induced gene 1  PAG608  p53-activated gene 608  Symbol and Name updated 1299863 APPROVED
2002-08-07 PAG608  p53-activated gene 608      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_cellular_localization localizes preferentially to nucleoli 633665
gene_regulation mRNA induced by p53 633665