Scpep1 (serine carboxypeptidase 1)

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Gene: Scpep1 (serine carboxypeptidase 1) Rattus norvegicus

Analyze

Symbol:

Scpep1

Name:

serine carboxypeptidase 1

RGD ID:

620067

Description:

Predicted to enable serine-type carboxypeptidase activity. Involved in retinoic acid metabolic process. Predicted to be located in extracellular region. Orthologous to human SCPEP1 (serine carboxypeptidase 1); INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 17beta-estradiol 3-benzoate.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

retinoid-inducible serine carboxypeptidase; retinoid-inducible serine caroboxypetidase; Risc

RGD Orthologs

Human

Mouse

Chinchilla

Bonobo

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	SCPEP1 (serine carboxypeptidase 1)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Scpep1 (serine carboxypeptidase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Scpep1 (serine carboxypeptidase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	SCPEP1 (serine carboxypeptidase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	SCPEP1 (serine carboxypeptidase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Scpep1 (serine carboxypeptidase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	SCPEP1 (serine carboxypeptidase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	SCPEP1 (serine carboxypeptidase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Scpep1 (serine carboxypeptidase 1)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Mus musculus (house mouse):	Scpep1 (serine carboxypeptidase 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	SCPEP1 (serine carboxypeptidase 1)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	scpep1 (serine carboxypeptidase 1)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG32483	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	hiro	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG31821	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	CG31823	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	Y32F6A.5	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	scpep1	Alliance	DIOPT (Ensembl Compara\|OMA\|OrthoFinder\|PANTHER\|PhylomeDB)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	10	73,703,275 - 73,732,892 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	10	73,703,278 - 73,732,850 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	10	78,318,490 - 78,347,988 (-)	NCBI	Rnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0	10	77,823,415 - 77,852,910 (-)	NCBI	Rnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0	10	73,286,585 - 73,316,078 (-)	NCBI	Rnor_WKY
Rnor_6.0	10	76,230,371 - 76,263,866 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	10	76,230,373 - 76,263,866 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	10	73,846,394 - 73,880,406 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	10	77,347,473 - 77,377,945 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	10	77,361,844 - 77,392,315 (-)	NCBI
Celera	10	72,609,315 - 72,638,737 (-)	NCBI		Celera
Cytogenetic Map	10	q26	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

COVID-19 (ISO)

genetic disease (ISO)

Joubert syndrome (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-schisandrin B (EXP)

1,2-dimethylhydrazine (ISO)

17alpha-ethynylestradiol (ISO)

17beta-estradiol (EXP)

17beta-estradiol 3-benzoate (EXP)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2,3,7,8-Tetrachlorodibenzofuran (ISO)

2-acetamidofluorene (EXP)

2-hydroxypropanoic acid (ISO)

2-methylcholine (ISO)

3,3',4,4',5-pentachlorobiphenyl (EXP)

3,4-methylenedioxymethamphetamine (EXP)

3-chloropropane-1,2-diol (EXP)

5-aza-2'-deoxycytidine (ISO)

acetamide (EXP)

aconitine (EXP)

aflatoxin B1 (ISO)

all-trans-retinoic acid (EXP,ISO)

ammonium chloride (EXP)

antirheumatic drug (ISO)

Aroclor 1254 (ISO)

arsenous acid (ISO)

benzo[a]pyrene (ISO)

benzo[a]pyrene diol epoxide I (ISO)

bis(2-ethylhexyl) phthalate (ISO)

bisphenol A (EXP,ISO)

bleomycin A2 (EXP)

bortezomib (ISO)

cadmium dichloride (EXP)

calcitriol (ISO)

carbon nanotube (ISO)

cisplatin (ISO)

cobalt dichloride (EXP,ISO)

diarsenic trioxide (ISO)

dorsomorphin (ISO)

doxorubicin (ISO)

endosulfan (EXP)

entinostat (ISO)

ethyl methanesulfonate (ISO)

flutamide (EXP)

folic acid (ISO)

formaldehyde (ISO)

genistein (EXP)

gentamycin (EXP)

glafenine (EXP)

indole-3-methanol (EXP)

isoprenaline (ISO)

ivermectin (ISO)

lithium chloride (ISO)

methyl methanesulfonate (ISO)

methylmercury chloride (ISO)

N-methyl-4-phenylpyridinium (ISO)

N-nitrosodiethylamine (EXP)

paracetamol (EXP,ISO)

phenobarbital (ISO)

piperonyl butoxide (EXP)

rac-lactic acid (ISO)

resveratrol (ISO)

rotenone (EXP)

SB 431542 (ISO)

Soman (EXP)

T-2 toxin (ISO)

tamoxifen (ISO)

Tesaglitazar (EXP)

testosterone (EXP,ISO)

testosterone enanthate (ISO)

tetrachloromethane (EXP,ISO)

trichloroethene (EXP)

trichostatin A (ISO)

triphenyl phosphate (EXP)

urethane (ISO)

valproic acid (ISO)

vorinostat (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

blood vessel diameter maintenance (ISO)

negative regulation of blood pressure (ISO)

proteolysis (IEA)

retinoic acid metabolic process (IEP)

Cellular Component

extracellular region (IEA)

Molecular Function

serine-type carboxypeptidase activity (IBA,IEA,ISO,TAS)

References

References - curated

#	Reference Title	Reference Citation
1.	Cloning of a novel retinoid-inducible serine carboxypeptidase from vascular smooth muscle cells.	Chen J, etal., J Biol Chem 2001 Sep 7;276(36):34175-81.
2.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
4.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
5.	GOA pipeline	RGD automated data pipeline
6.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:19056867	PMID:19199708	PMID:23376485	PMID:23533145	PMID:24586188

Genomics

Comparative Map Data

Scpep1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	10	73,703,275 - 73,732,892 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	10	73,703,278 - 73,732,850 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	10	78,318,490 - 78,347,988 (-)	NCBI	Rnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0	10	77,823,415 - 77,852,910 (-)	NCBI	Rnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0	10	73,286,585 - 73,316,078 (-)	NCBI	Rnor_WKY
Rnor_6.0	10	76,230,371 - 76,263,866 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	10	76,230,373 - 76,263,866 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	10	73,846,394 - 73,880,406 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	10	77,347,473 - 77,377,945 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	10	77,361,844 - 77,392,315 (-)	NCBI
Celera	10	72,609,315 - 72,638,737 (-)	NCBI		Celera
Cytogenetic Map	10	q26	NCBI

SCPEP1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	17	56,978,131 - 57,006,768 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p13 Ensembl	17	56,978,129 - 57,006,768 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	17	55,055,492 - 55,084,129 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	17	52,410,467 - 52,439,128 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	17	52,410,487 - 52,439,123	NCBI
Celera	17	51,517,044 - 51,545,707 (+)	NCBI		Celera
Cytogenetic Map	17	q22	NCBI
HuRef	17	50,416,496 - 50,445,158 (+)	NCBI		HuRef
CHM1_1	17	55,120,690 - 55,149,356 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	17	57,855,772 - 57,884,410 (+)	NCBI		T2T-CHM13v2.0

Scpep1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	11	88,814,846 - 88,846,268 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	11	88,814,846 - 88,846,291 (-)	Ensembl		GRCm39 Ensembl
GRCm38	11	88,924,020 - 88,955,442 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	11	88,924,020 - 88,955,465 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	11	88,785,334 - 88,816,756 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	11	88,740,110 - 88,771,522 (-)	NCBI		MGSCv36	mm8
Celera	11	98,535,098 - 98,568,204 (-)	NCBI		Celera
Cytogenetic Map	11	C	NCBI

Scpep1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955451	5,846,552 - 5,876,851 (-)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955451	5,847,371 - 5,876,286 (-)	NCBI	ChiLan1.0	ChiLan1.0

SCPEP1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1	17	77,961,953 - 77,990,686 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	17	51,055,293 - 51,084,032 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	17	55,915,746 - 55,944,374 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	17	55,915,746 - 55,944,377 (+)	Ensembl	panpan1.1		panPan2

SCPEP1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	9	31,770,494 - 31,803,741 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	9	31,774,602 - 31,803,741 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	9	31,010,418 - 31,043,464 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	9	32,578,347 - 32,611,364 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	9	32,578,396 - 32,611,601 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	9	31,363,955 - 31,397,132 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	9	31,647,649 - 31,680,837 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	9	31,731,073 - 31,764,270 (+)	NCBI		UU_Cfam_GSD_1.0

Scpep1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405602	31,143,599 - 31,171,166 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936490	5,904,396 - 5,939,915 (-)	Ensembl	SpeTri2.0
SpeTri2.0	NW_004936490	5,903,884 - 5,939,953 (-)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

SCPEP1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	12	33,265,562 - 33,298,142 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	12	33,265,509 - 33,296,805 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	12	33,995,016 - 34,027,373 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

SCPEP1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	16	36,398,059 - 36,427,429 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	16	36,398,615 - 36,427,404 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666077	7,216,719 - 7,246,075 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Scpep1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624795	12,016,302 - 12,042,353 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624795	12,016,363 - 12,041,615 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Scpep1
160 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	333
Count of miRNA genes:	200
Interacting mature miRNAs:	227
Transcripts:	ENSRNOT00000003219
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
70223	Bp57	Blood pressure QTL 57	5		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	10	1	80676123	Rat
61427	Cia16	Collagen induced arthritis QTL 16	3.2		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	6357896	96121100	Rat
2303118	Mamtr7	Mammary tumor resistance QTL 7		0.003	mammary gland integrity trait (VT:0010552)	mammary tumor growth rate (CMO:0000344)	10	9658275	104670812	Rat
2301967	Cm73	Cardiac mass QTL 73	4.55		heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	10	14487011	89062041	Rat
631268	Cia21	Collagen induced arthritis QTL 21	3.1		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	14487011	104060283	Rat
2316949	Gluco60	Glucose level QTL 60	3.7		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	10	14487011	107057807	Rat
1554317	Bmd4	Bone mineral density QTL 4	9.4	0.0001	lumbar vertebra mineral mass (VT:0010511)	volumetric bone mineral density (CMO:0001553)	10	19816042	99406971	Rat
724556	Pur2	Proteinuria QTL 2	5.5		urine protein amount (VT:0005160)	urine protein level (CMO:0000591)	10	22427500	90627625	Rat
61354	Pia10	Pristane induced arthritis QTL 10		0.01	joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	23444813	104060283	Rat
631267	Cia20	Collagen induced arthritis QTL 20	3.2		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	23444813	104060283	Rat
61325	Aia5	Adjuvant induced arthritis QTL 5		0.01	joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	23444813	104060283	Rat
1298069	Bp168	Blood pressure QTL 168	5.5		blood pressure trait (VT:0000183)	systolic blood pressure (CMO:0000004)	10	26521957	98003205	Rat
631542	Bp82	Blood pressure QTL 82	6.8		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	10	26521957	98952741	Rat
1331791	Cm31	Cardiac mass QTL 31	3.84606		heart mass (VT:0007028)	heart wet weight (CMO:0000069)	10	29299504	107211142	Rat
631557	Bp136	Blood pressure QTL 136		0.003	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	10	30632053	75632053	Rat
1576311	Pia26	Pristane induced arthritis QTL 26			joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	31224026	75632053	Rat
1578779	Tcas10	Tongue tumor susceptibility QTL 10	3.12		tongue integrity trait (VT:0010553)	number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)	10	31297439	76297439	Rat
1576319	Cia29	Collagen induced arthritis QTL 29			joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	33973921	78973921	Rat
2317042	Aia20	Adjuvant induced arthritis QTL 20	3.38		joint integrity trait (VT:0010548)	right rear ankle joint diameter (CMO:0002150)	10	37565079	82565079	Rat
2317043	Aia7	Adjuvant induced arthritis QTL 7	3.82		joint integrity trait (VT:0010548)	left rear ankle joint diameter (CMO:0002149)	10	37565079	82565079	Rat
1576308	Schws1	Schwannoma susceptibility QTL 1		0.0041	nervous system integrity trait (VT:0010566)	percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)	10	40035094	102359817	Rat
631269	Cia22	Collagen induced arthritis QTL 22	8.9		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	40035094	104060283	Rat
631270	Cia23	Collagen induced arthritis QTL 23	3.9		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	10	40035094	104060283	Rat
631552	Vetf2	Vascular elastic tissue fragility QTL 2	4.5	0.0002	aorta elastic tissue integrity trait (VT:0010556)	artery internal elastic lamina non-tumorous lesion count (CMO:0001913)	10	41142633	86142633	Rat
61463	Bp12	Blood pressure QTL 12	6.3	0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	10	41333258	86333258	Rat
8552805	Bw145	Body weight QTL 145	2.2		body mass (VT:0001259)	change in body weight to body weight ratio (CMO:0002216)	10	41944526	78307017	Rat
1298078	Stresp5	Stress response QTL 5	2.99	0.00025	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	10	42045676	104670812	Rat
70188	BpQTLcluster1	Blood pressure QTL cluster 1	4.864		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	1	42323132	87323132	Rat
70188	BpQTLcluster1	Blood pressure QTL cluster 1	4.864		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	1	42323132	87323132	Rat
70188	BpQTLcluster1	Blood pressure QTL cluster 1	4.864		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	1	42323132	87323132	Rat
70188	BpQTLcluster1	Blood pressure QTL cluster 1	4.864		arterial blood pressure trait (VT:2000000)	pulse pressure (CMO:0000292)	1	42323132	87323132	Rat
70198	BpQTLcluster9	Blood pressure QTL cluster 9	2.94		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	10	42323132	87323132	Rat
6893342	Cm78	Cardiac mass QTL 78	0.1	0.88	heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	10	42876766	79813922	Rat
9589030	Epfw9	Epididymal fat weight QTL 9	19.24	0.001	epididymal fat pad mass (VT:0010421)	epididymal fat pad weight to body weight ratio (CMO:0000658)	10	44441699	89441699	Rat
7411614	Foco18	Food consumption QTL 18		0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	10	44441699	89441699	Rat
8694173	Bw149	Body weight QTL 149	4.38	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	10	44441699	89441699	Rat
2300218	Hpcl2	Hepatic cholesterol level QTL 2			liver cholesterol amount (VT:0010498)	liver cholesterol level (CMO:0001597)	10	45029650	95600334	Rat
631547	Bp87	Blood pressure QTL 87	4.5		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	10	47369470	92369470	Rat
2293705	Bmd25	Bone mineral density QTL 25	7.1	0.0001	femur mineral mass (VT:0010011)	compact volumetric bone mineral density (CMO:0001730)	10	49444551	81709989	Rat
7207811	Bmd90	Bone mineral density QTL 90	5.2		femur size trait (VT:1000369)	femoral neck cross-sectional area (CMO:0001697)	10	49444551	81709989	Rat
2293652	Bmd22	Bone mineral density QTL 22	4.9	0.0001	femur mineral mass (VT:0010011)	total volumetric bone mineral density (CMO:0001728)	10	49444551	81709989	Rat
2293669	Bmd33	Bone mineral density QTL 33	4.5	0.0001	femur strength trait (VT:0010010)	femoral neck polar moment of inertia (CMO:0001670)	10	49444551	81709989	Rat
2293679	Bmd30	Bone mineral density QTL 30	3.5	0.0001	femur mineral mass (VT:0010011)	total volumetric bone mineral density (CMO:0001728)	10	49444551	81709989	Rat
1549846	Scl47	Serum cholesterol level QTL 47	3.6		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	10	50574707	95574707	Rat
70364	Bp72	Blood pressure QTL 72			arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	10	51121100	96121100	Rat
61387	Bp1	Blood pressure QTL 1	5.1		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	10	51770177	107211142	Rat
61387	Bp1	Blood pressure QTL 1	5.1		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	10	51770177	107211142	Rat
1359017	Hrtrt21	Heart rate QTL 21	2.4		heart pumping trait (VT:2000009)	heart rate (CMO:0000002)	10	51772940	96772940	Rat
631530	Tls3	T-lymphoma susceptibility QTL 3	0	0.0001	thymus integrity trait (VT:0010555)	percentage of study population developing T-cell lymphomas during a period of time (CMO:0001911)	10	51774612	95600334	Rat
631535	Cm51	Cardiac mass QTL 51	3		heart mass (VT:0007028)	calculated heart weight (CMO:0000073)	10	51786282	91669536	Rat
70171	Cari1	Carrageenan-induced inflammation QTL 1	4.9	0.0005	hypodermis integrity trait (VT:0010550)	inflammatory exudate volume (CMO:0001429)	10	53797385	107211142	Rat
70164	Bw21	Body weight QTL 21	4.36	0.00005	body mass (VT:0001259)	body weight (CMO:0000012)	10	53797494	98952626	Rat
1354608	Cm33	Cardiac mass QTL 33	2.8		heart left ventricle mass (VT:0007031)	heart left ventricle wet weight (CMO:0000071)	10	54809292	99809292	Rat
2312662	Slep8	Serum leptin concentration QTL 8		0.05	blood leptin amount (VT:0005667)	serum leptin level (CMO:0000780)	10	57134272	102134272	Rat
2312668	Scl65	Serum cholesterol level QTL 65		0.001	blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	10	57134272	102134272	Rat
2312672	Insul15	Insulin level QTL 15		0.01	blood insulin amount (VT:0001560)	serum insulin level (CMO:0000358)	10	57134272	102134272	Rat
1549831	Bss6	Bone structure and strength QTL 6	4		lumbar vertebra strength trait (VT:0010574)	vertebra ultimate force (CMO:0001678)	10	57576521	102576521	Rat
2293698	Bss43	Bone structure and strength QTL 43	5.33	0.0001	lumbar vertebra size trait (VT:0010518)	lumbar vertebra cross-sectional area (CMO:0001689)	10	59209888	104209888	Rat
70363	Bp71	Blood pressure QTL 71		0.04	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	10	61345276	81714865	Rat
2306970	Anxrr22	Anxiety related response QTL 22	5.95		fear/anxiety-related behavior trait (VT:1000241)	number of periods of voluntary immobility (CMO:0001045)	10	61345276	98211570	Rat
6893336	Cm75	Cardiac mass QTL 75	0.1	0.87	heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	10	61345276	99703528	Rat
1558643	Cm44	Cardiac mass QTL 44	4.8	0.0000368	heart mass (VT:0007028)	heart wet weight (CMO:0000069)	10	61345276	99703528	Rat
61402	Niddm3	Non-insulin dependent diabetes mellitus QTL 3	4.58		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	10	61345413	82564856	Rat
2313103	Bss80	Bone structure and strength QTL 80	2	0.0001	tibia strength trait (VT:1000284)	tibia midshaft endosteal cross-sectional area (CMO:0001716)	10	62057807	107057807	Rat
2313105	Bss79	Bone structure and strength QTL 79	1.8	0.0001	tibia size trait (VT:0100001)	tibia midshaft cross-sectional area (CMO:0001717)	10	62057807	107057807	Rat
61449	Ciaa2	CIA Autoantibody QTL 2	7.1		blood autoantibody amount (VT:0003725)	calculated serum anti-type 2 collagen antibody titer (CMO:0001279)	10	63221094	107211142	Rat
2298481	Eau9	Experimental allergic uveoretinitis QTL 9		0.0169	uvea integrity trait (VT:0010551)	experimental autoimmune uveitis score (CMO:0001504)	10	65927233	82565079	Rat
1357344	Bp249	Blood pressure QTL 249		0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	10	66743655	98003205	Rat
2317029	Aia19	Adjuvant induced arthritis QTL 19	2.98		joint integrity trait (VT:0010548)	left rear ankle joint diameter (CMO:0002149)	10	66978955	107211142	Rat
2317039	Aia6	Adjuvant induced arthritis QTL 6	4.31		joint integrity trait (VT:0010548)	right rear ankle joint diameter (CMO:0002150)	10	66978955	107211142	Rat
10450498	Bp384	Blood pressure QTL 384		0.002	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	10	67750049	107211142	Rat
1642980	Bp300	Blood pressure QTL 300			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	10	68383129	107211142	Rat
61396	Bp9	Blood pressure QTL 9	4.8	0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	10	68420376	107211142	Rat
2300172	Bmd57	Bone mineral density QTL 57	9.8	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	10	69738412	107211142	Rat
2293646	Bss25	Bone structure and strength QTL 25	10.96	0.0001	femur morphology trait (VT:0000559)	femur cross-sectional area (CMO:0001661)	10	69738412	107211142	Rat
2293663	Bss33	Bone structure and strength QTL 33	9.34	0.0001	femur strength trait (VT:0010010)	femur midshaft polar moment of inertia (CMO:0001669)	10	69738412	107211142	Rat
6893366	Bw106	Body weight QTL 106	0.3	0.47	body mass (VT:0001259)	body weight (CMO:0000012)	10	70199100	107211142	Rat
70193	Mcs7	Mammary carcinoma susceptibility QTL 7	2.38		mammary gland integrity trait (VT:0010552)	mammary tumor number (CMO:0000343)	10	72224939	107211142	Rat
2298548	Neuinf7	Neuroinflammation QTL 7	3.4		nervous system integrity trait (VT:0010566)	spinal cord RT1-B protein level (CMO:0002132)	10	72224939	107211142	Rat
2306793	Ean5	Experimental allergic neuritis QTL 5	4.7		nervous system integrity trait (VT:0010566)	IFNG-secreting splenocyte count (CMO:0002122)	10	72552416	93995749	Rat
2289982	Bp303	Blood pressure QTL 303			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	10	73452992	75632053	Rat
724555	Bp150	Blood pressure QTL 150		0.0001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	10	73452992	78210622	Rat
12880053	Cm104	Cardiac mass QTL 104		0.009	heart right ventricle mass (VT:0007033)	heart right ventricle weight to body weight ratio (CMO:0000914)	10	73452992	83463334	Rat
1358188	Ept9	Estrogen-induced pituitary tumorigenesis QTL 9	3.9		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	10	73453136	96120911	Rat
2292617	Ept18	Estrogen-induced pituitary tumorigenesis QTL 18	3.9		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	10	73453136	96120911	Rat
2289983	Bp304	Blood pressure QTL 304			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	10	73579541	74119158	Rat

Markers in Region

D10Got230

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	10	73,723,598 - 73,723,784 (+)	MAPPER	mRatBN7.2
Rnor_6.0	10	76,254,639 - 76,254,823	NCBI	Rnor6.0
Rnor_5.0	10	73,855,346 - 73,855,530	UniSTS	Rnor5.0
RGSC_v3.4	10	77,368,719 - 77,368,903	UniSTS	RGSC3.4
Celera	10	72,629,531 - 72,629,715	UniSTS
Cytogenetic Map	10	q26	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium	3	43	57	41	19	41	8	11	74	35	38	11	8
Low											3
Below cutoff

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_133383	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017596951	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039085041	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039085042	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC119015	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AF330051	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473948	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ235041	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000220	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSRNOT00000003219 ⟹ ENSRNOP00000003219

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	10	73,703,278 - 73,732,850 (-)	Ensembl
Rnor_6.0 Ensembl	10	76,230,373 - 76,263,866 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000104820 ⟹ ENSRNOP00000092430

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	10	73,703,278 - 73,732,821 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000110780 ⟹ ENSRNOP00000081360

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	10	73,703,283 - 73,732,821 (-)	Ensembl

RefSeq Acc Id:

NM_133383 ⟹ NP_596874

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	10	73,703,275 - 73,732,829 (-)	NCBI
Rnor_6.0	10	76,230,371 - 76,263,866 (-)	NCBI
Rnor_5.0	10	73,846,394 - 73,880,406 (+)	NCBI
RGSC_v3.4	10	77,347,473 - 77,377,945 (-)	RGD
Celera	10	72,609,315 - 72,638,737 (-)	RGD

Sequence:

show sequence

CTGAGGCGGGGTTTTCATCATGGAGCTGTCGCGGCGGATTTGTCTCGTCCGACTGTGGCTGTTG
CTACTGTCGTTCTTGCTGGGCTTCAGCGCGGGATCTGCCCTCAACTGGCGGGAACAAGAAGGCA
AGGAAGTATGGGATTACGTGACTGTTCGAGAGGATGCACGCATGTTCTGGTGGCTCTACTATGC
CACCAACCCTTGCAAGAACTTCTCAGAGCTGCCTCTGGTCATGTGGCTTCAGGGTGGTCCAGGT
GGTTCTAGCACTGGATTTGGAAACTTTGAGGAAATCGGCCCTCTTGACACCCGACTCAAGCCAC
GGAACACTACCTGGCTGCAGTGGGCCAGTCTCCTGTTTGTGGACAATCCTGTGGGCACGGGCTT
CAGTTACGTGAACACGACAGATGCCTACGCAAAGGACCTGGACACGGTGGCTTCCGACATGATG
GTCCTCCTGAAATCCTTCTTTGATTGTCATAAAGAATTCCAGACGGTTCCGTTCTACATTTTCT
CAGAATCCTACGGAGGAAAGATGGCTGCTGGCATCAGTTTAGAACTTCACAAGGCTATTCAGCA
AGGGACCATCAAGTGCAACTTCTCTGGGGTTGCTTTGGGTGACTCCTGGATCTCCCCTGTGGAT
TCAGTGCTGTCCTGGGGACCTTACCTGTACAGCGTGTCTCTCCTTGATAATAAAGGCTTGGCTG
AGGTGTCCGACATTGCGGAGCAAGTCCTCAATGCTGTAAACAAGGGCTTCTACAAGGAAGCCAC
TCAGCTGTGGGGGAAAGCAGAAATGATCATTGAAAAGAACACCGACGGGGTAAACTTCTATAAC
ATCTTAACTAAAAGCACCCCCGACACCTCTATGGAGTCGAGCCTCGAGTTCTTCCGGAGCCCCT
TAGTTCGTCTCTGTCAGCGCCACGTGAGACACCTACAAGGAGACGCCTTAAGTCAGCTCATGAA
CGGTCCCATCAAAAAGAAGCTCAAAATTATCCCTGACGATGTCTCCTGGGGAGCCCAGTCGTCC
TCCGTCTTCATAAGCATGGAAGAGGACTTCATGAAGCCTGTCATCGACATCGTGGATACGTTGC
TGGAACTCGGGGTCAATGTGACTGTGTACAATGGGCAGCTGGATCTCATTGTGGACACCATAGG
TCAGGAGTCCTGGGTTCAGAAGCTGAAGTGGCCACAGCTGTCCAGATTCAATCAGCTAAAATGG
AAGGCCCTGTACACCAATCCTAAGTCTTCAGAAACATCTGCGTTTGTCAAGTCCTATGAGAACT
TAGCGTTCTACTGGATCCTAAAGGCGGGTCACATGGTTCCTGCTGACCAAGGGGACATGGCTCT
GAAGATGATGAGGCTGGTTACTCAGCAGGAGTAGCTGAGCTGAGCTGGCCCTGGAGGCCCTGGA
GGCCCTGGAGGCCCTGGAGTAGGGCCCAGGATGCAGGTGCTAATGTCTATCCCCGGCGCTCTTC
TTCCCGACTCTACCATGGGATGTAACTCCAGGAGCCCCTGCCATCTCCCGTACCAAAAGACTGT
GGCTTCCGTGTCTACTCAGAAATCAGTTCTACTTCGTAAACAGTGTTTAAAACCAGACTCATTT
AATCAGAGTGAAGGATTGCAGTCCATTGGCTTCTTAGCACAGAAGCAGCTGATAACACAAGTAA
ACCCCAGCCCTTGAGAGGTAGAAGCAAGAGGATCAGAGGTTCAAGCGCATCCTCGGCTCCATCA
TAAGTTCAAAAGCCGCCTGCACCAAATGGGAGTCCTTGTCTCAAAAAAAAAAAAAAAAAAAAAA
AAGCAAAGAAAGCAAAGGACTCGATGACATGATTTATAGACAAAAGCAGTGGGAGAAAATACTA
AAGCCCCACTGAGCTGCCAGCCAGGTGTCTGTGACTACAGGTCTTTTATCTGCTACATATATAT
TTTTACAAAAATGAAATCCATATTGTTCGCTATTTTGCTGTCTGCTTTGCTCCCGTATCAACAT
GACTTGCACGTCTTTTCCCATCAATAAATGTGCCATGATATTTTTAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_017596951 ⟹ XP_017452440

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	10	73,703,275 - 73,732,867 (-)	NCBI
Rnor_6.0	10	76,230,371 - 76,263,861 (-)	NCBI

Sequence:

show sequence

GCGGGGTTTTCATCATGGAGCTGTCGCGGCGGATTTGTCTCGTCCGACTGTGGCTGTTGCTACT
GTCGTTCTTGCTGGGCTTCAGCGCGGCGTACTGAAGTAGATAATTACCTAAAGCATAAAGTGCC
ATCTCTAGCCTGAATGACCTTCTCTACCGAACTTGGAACTCACCTGGAGTGCTCTACCCCATCA
TCTTTACCACTTCAGAACTCCTCAGGAAATGACTCTGAGCTCCCGTTTTCAGGATCTGCCCTCA
ACTGGCGGGAACAAGAAGGCAAGGAAGTATGGGATTACGTGACTGTTCGAGAGGATGCACGCAT
GTTCTGGTGGCTCTACTATGCCACCAACCCTTGCAAGAACTTCTCAGAGCTGCCTCTGGTCATG
TGGCTTCAGGGTGGTCCAGGTGGTTCTAGCACTGGATTTGGAAACTTTGAGGAAATCGGCCCTC
TTGACACCCGACTCAAGCCACGGAACACTACCTGGCTGCAGTGGGCCAGTCTCCTGTTCGTGGA
CAATCCTGTGGGCACGGGCTTCAGTTACGTGAACACGACAGATGCCTACGCAAAGGACCTGGAC
ACGGTGGCTTCCGACATGATGGTCCTCCTGAAATCCTTCTTTGATTGTCATAAAGAATTCCAGA
CGGTTCCGTTCTACATTTTCTCAGAATCCTACGGAGGAAAGATGGCTGCTGGCATCAGTTTAGA
ACTTCACAAGGCTATTCAGCAAGGGACCATCAAGTGCAACTTCTCTGGGGTTGCTTTGGGTGAC
TCCTGGATCTCCCCTGTGGATTCAGTGCTGTCCTGGGGACCTTACCTGTACAGCGTGTCTCTCC
TTGATAATAAAGGCTTGGCTGAGGTGTCCGACATTGCGGAGCAAGTCCTCAATGCTGTAAACAA
GGGCTTCTACAAGGAAGCCACTCAGCTGTGGGGGAAAGCAGAAATGATCATTGAAAAGAACACC
GACGGGGTAAACTTCTATAACATCTTAACTAAAAGCACCCCCGACACCTCTATGGAGTCGAGCC
TCGAGTTCTTCCGGAGCCCCTTAGTTCGTCTCTGTCAGCGCCACGTGAGACACCTACAAGGAGA
CGCCTTAAGTCAGCTCATGAACGGTCCCATCAAAAAGAAGCTCAAAATTATCCCTGACGATGTC
TCCTGGGGAGCCCAGTCGTCCTCCGTCTTCATAAGCATGGAAGAGGACTTCATGAAGCCTGTCA
TCGACATCGTGGATACGTTGCTGGAACTCGGGGTCAATGTGACTGTGTACAATGGGCAGCTGGA
TCTCATTGTGGACACCATAGGTCAGGAGTCCTGGGTTCAGAAGCTGAAGTGGCCACAGCTGTCC
AGATTCAATCAGCTAAAATGGAAGGCCCTGTACACCAATCCTAAGTCTTCAGAAACATCTGCGT
TTGTCAAGTCCTATGAGAACCTAGCGTTCTACTGGATCCTAAAGGCGGGTCACATGGTTCCTGC
TGACCAAGGGGACATGGCTCTGAAGATGATGAGGCTGGTTACTCAGCAGGAGTAGCTGAGCTGA
GCTGGCCCTGGAGGCCCTGGAGGCCCTGGAGTAGGGCCCAGGATGCAGGTGCTAATGTCTATCC
CCGGCGCTCTTCTTCCCGACTCTACCATGGGATGTAACTCCAGGAGCCCCTGCCATCTCCCGTA
CCAAAAGACTGTGGCTTCCGTGTCTACTCAGAAATCAGTTCTACTTCGTAAACAGTGTTTAAAA
CCAGACTCATTTAATCAGAGTGAAGGATTGCAGTCCATTGGCTTCTTAGCACAGAAGCAGCTGA
TAACACAAGTAAACCCCAGCCCTTGAGAGGTAGAAGCAAGAGGATCAGAGGTTCAAGCGCATCC
TCGGCTCCATCACAAGTTCAAAAGCCGCCTGCACCAAATGGGAGTCCTTGTCTCAAAAAAAAAA
AAAAAAAAAAGCAAAGAAAGCAAAGGACTCGATGACATGATTTATAGACAAAAGCAGTGGGAGA
AAATACTAAAGCCCCACTGAGCTGCCAGCCAGGTGTCTGTGACTACAGGTCTTTTATCTGCTAC
ATATATATTTTTACAAAAATGAAATCCATATTGTTCGCTATTTTGCTGTCTGCTTTGCTCCCGT
ATCAACATGACTTGCACGTCTTTTCCCATCAATAAATGTGCCATGATATTTTTAA

hide sequence

RefSeq Acc Id:

XM_039085041 ⟹ XP_038940969

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	10	73,703,275 - 73,732,817 (-)	NCBI

RefSeq Acc Id:

XM_039085042 ⟹ XP_038940970

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	10	73,703,275 - 73,732,892 (-)	NCBI

Protein Sequences


Protein RefSeqs	NP_596874	(Get FASTA)	NCBI Sequence Viewer
	XP_017452440	(Get FASTA)	NCBI Sequence Viewer
	XP_038940969	(Get FASTA)	NCBI Sequence Viewer
	XP_038940970	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAK84661	(Get FASTA)	NCBI Sequence Viewer
	EDM05646	(Get FASTA)	NCBI Sequence Viewer
	EDM05647	(Get FASTA)	NCBI Sequence Viewer
	EDM05648	(Get FASTA)	NCBI Sequence Viewer
	Q920A6	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:	NP_596874 ⟸ NM_133383
- Peptide Label:	precursor
- UniProtKB:	Q920A6 (UniProtKB/Swiss-Prot)
- Sequence:	show sequence MELSRRICLVRLWLLLLSFLLGFSAGSALNWREQEGKEVWDYVTVREDARMFWWLYYATNPCKN FSELPLVMWLQGGPGGSSTGFGNFEEIGPLDTRLKPRNTTWLQWASLLFVDNPVGTGFSYVNTT DAYAKDLDTVASDMMVLLKSFFDCHKEFQTVPFYIFSESYGGKMAAGISLELHKAIQQGTIKCN FSGVALGDSWISPVDSVLSWGPYLYSVSLLDNKGLAEVSDIAEQVLNAVNKGFYKEATQLWGKA EMIIEKNTDGVNFYNILTKSTPDTSMESSLEFFRSPLVRLCQRHVRHLQGDALSQLMNGPIKKK LKIIPDDVSWGAQSSSVFISMEEDFMKPVIDIVDTLLELGVNVTVYNGQLDLIVDTIGQESWVQ KLKWPQLSRFNQLKWKALYTNPKSSETSAFVKSYENLAFYWILKAGHMVPADQGDMALKMMRLV TQQE hide sequence

RefSeq Acc Id:	XP_017452440 ⟸ XM_017596951
- Peptide Label:	isoform X1
- UniProtKB:	A0A8I6AI52 (UniProtKB/TrEMBL)
- Sequence:	show sequence MTFSTELGTHLECSTPSSLPLQNSSGNDSELPFSGSALNWREQEGKEVWDYVTVREDARMFWWL YYATNPCKNFSELPLVMWLQGGPGGSSTGFGNFEEIGPLDTRLKPRNTTWLQWASLLFVDNPVG TGFSYVNTTDAYAKDLDTVASDMMVLLKSFFDCHKEFQTVPFYIFSESYGGKMAAGISLELHKA IQQGTIKCNFSGVALGDSWISPVDSVLSWGPYLYSVSLLDNKGLAEVSDIAEQVLNAVNKGFYK EATQLWGKAEMIIEKNTDGVNFYNILTKSTPDTSMESSLEFFRSPLVRLCQRHVRHLQGDALSQ LMNGPIKKKLKIIPDDVSWGAQSSSVFISMEEDFMKPVIDIVDTLLELGVNVTVYNGQLDLIVD TIGQESWVQKLKWPQLSRFNQLKWKALYTNPKSSETSAFVKSYENLAFYWILKAGHMVPADQGD MALKMMRLVTQQE hide sequence

RefSeq Acc Id:

ENSRNOP00000003219 ⟸ ENSRNOT00000003219

RefSeq Acc Id:	XP_038940970 ⟸ XM_039085042
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038940969 ⟸ XM_039085041
- Peptide Label:	isoform X1
- UniProtKB:	A0A8I6AI52 (UniProtKB/TrEMBL)

RefSeq Acc Id:

ENSRNOP00000092430 ⟸ ENSRNOT00000104820

RefSeq Acc Id:

ENSRNOP00000081360 ⟸ ENSRNOT00000110780

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q920A6-F1-model_v2	AlphaFold	Q920A6	1-452	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13697582

Promoter ID:

EPDNEW_R8107

Type:

initiation region

Name:

Scpep1_1

Description:

serine carboxypeptidase 1

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	10	76,263,856 - 76,263,916	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:620067	AgrOrtholog
BioCyc Gene	G2FUF-23706	BioCyc
Ensembl Genes	ENSRNOG00000002358	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein	ENSRNOP00000003219	ENTREZGENE
	ENSRNOP00000003219.3	UniProtKB/TrEMBL
	ENSRNOP00000081360	ENTREZGENE
	ENSRNOP00000081360.1	UniProtKB/TrEMBL
	ENSRNOP00000092430	ENTREZGENE
	ENSRNOP00000092430.1	UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000003219	ENTREZGENE
	ENSRNOT00000003219.4	UniProtKB/TrEMBL
	ENSRNOT00000104820	ENTREZGENE
	ENSRNOT00000104820.1	UniProtKB/TrEMBL
	ENSRNOT00000110780	ENTREZGENE
	ENSRNOT00000110780.1	UniProtKB/TrEMBL
Gene3D-CATH	3.40.50.1820	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro	AB_hydrolase	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Peptidase_S10	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	Ser_caboxypep_ser_AS	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	rno:114861	UniProtKB/Swiss-Prot
NCBI Gene	114861	ENTREZGENE
PANTHER	PTHR11802	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	RETINOID-INDUCIBLE SERINE CARBOXYPEPTIDASE	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	Peptidase_S10	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Scpep1	PhenoGen
PRINTS	CRBOXYPTASEC	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE	CARBOXYPEPT_SER_SER	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP	SSF53474	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	A0A8I5ZSM7_RAT	UniProtKB/TrEMBL
	A0A8I6AI52	ENTREZGENE, UniProtKB/TrEMBL
	A0A8L2Q1H7_RAT	UniProtKB/TrEMBL
	Q920A6	ENTREZGENE, UniProtKB/Swiss-Prot

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2004-12-14	Scpep1	serine carboxypeptidase 1	Risc	retinoid-inducible serine caroboxypetidase	Symbol and Name updated	1299863	APPROVED
2002-08-07	Risc				Symbol and Name status set to provisional	70820	PROVISIONAL

RGD Curation Notes

Note Type	Note	Reference
gene_regulation	expression is induced by retinoic acid	70518

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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