Pdzd2 (PDZ domain containing 2) - Rat Genome Database

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Gene: Pdzd2 (PDZ domain containing 2) Rattus norvegicus
Analyze
Symbol: Pdzd2
Name: PDZ domain containing 2
RGD ID: 619958
Description: Predicted to be involved in intracellular signal transduction. Located in several cellular components, including cell-cell junction; endoplasmic reticulum; and postsynaptic density. Orthologous to human PDZD2 (PDZ domain containing 2); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,6-dinitrotoluene; 3,3',4,4',5-pentachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC102546845; Papin; PDZ domain containing 3; PDZ domain-containing protein 2; PDZ domain-containing protein 3; Pdzk3; plakophilin-related armadillo repeat protein-interacting PDZ protein; uncharacterized LOC102546845; uncharacterized protein LOC102546845
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2261,384,614 - 61,770,516 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl261,386,381 - 61,770,524 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx268,516,647 - 68,749,894 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0266,636,963 - 66,872,612 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0261,638,440 - 61,874,092 (-)NCBIRnor_WKY
Rnor_6.0262,399,748 - 62,520,448 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl262,399,748 - 62,634,785 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0282,168,243 - 82,288,609 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4261,828,127 - 61,953,671 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1261,756,359 - 61,864,415 (-)NCBI
Celera257,076,815 - 57,309,194 (+)NCBICelera
Cytogenetic Map2q16NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
17beta-estradiol  (ISO)
2,3',4,4',5-Pentachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,6-dinitrotoluene  (EXP)
2-hydroxypropanoic acid  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (EXP)
3,4-methylenedioxymethamphetamine  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxyphenyl retinamide  (ISO)
acrylamide  (EXP,ISO)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
all-trans-retinoic acid  (ISO)
ammonium chloride  (EXP)
antirheumatic drug  (ISO)
aristolochic acid  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
azoxystrobin  (EXP)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
benzo[e]pyrene  (ISO)
bisphenol A  (EXP,ISO)
C60 fullerene  (EXP)
calcitriol  (ISO)
capsaicin  (EXP)
carbon nanotube  (ISO)
chlorpyrifos  (EXP)
crocidolite asbestos  (ISO)
cumene  (ISO)
diarsenic trioxide  (ISO)
dibutyl phthalate  (EXP)
dioxygen  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
endosulfan  (EXP)
ethanol  (ISO)
flavonoids  (EXP)
folic acid  (ISO)
fulvestrant  (ISO)
gentamycin  (EXP)
glyphosate  (EXP)
GW 4064  (ISO)
imidacloprid  (EXP)
Indeno[1,2,3-cd]pyrene  (ISO)
lipopolysaccharide  (ISO)
mercury dichloride  (EXP)
methapyrilene  (ISO)
methylmercury chloride  (ISO)
N,N-diethyl-m-toluamide  (EXP)
nickel atom  (ISO)
nickel dichloride  (ISO)
nickel sulfate  (ISO)
ozone  (ISO)
p-chloromercuribenzoic acid  (ISO)
paracetamol  (EXP)
paraquat  (EXP)
permethrin  (EXP)
potassium chromate  (ISO)
progesterone  (ISO)
rac-lactic acid  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
SB 431542  (ISO)
serpentine asbestos  (ISO)
sodium arsenate  (ISO)
sulforaphane  (ISO)
tert-butyl hydroperoxide  (ISO)
thiabendazole  (EXP)
titanium dioxide  (ISO)
valproic acid  (EXP,ISO)
vancomycin  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. PAPIN. A novel multiple PSD-95/Dlg-A/ZO-1 protein interacting with neural plakophilin-related armadillo repeat protein/delta-catenin and p0071. Deguchi M, etal., J Biol Chem 2000 Sep 22;275(38):29875-80.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Sensory neuron proteins interact with the intracellular domains of sodium channel NaV1.8. Malik-Hall M, etal., Brain Res Mol Brain Res. 2003 Feb 20;110(2):298-304.
4. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
5. GOA pipeline RGD automated data pipeline
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
8. Proteolytic cleavage of PDZD2 generates a secreted peptide containing two PDZ domains. Yeung ML, etal., EMBO Rep. 2003 Apr;4(4):412-8. Epub 2003 Mar 14.
Additional References at PubMed
PMID:11289102   PMID:12477932   PMID:19607921   PMID:32919022  


Genomics

Comparative Map Data
Pdzd2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2261,384,614 - 61,770,516 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl261,386,381 - 61,770,524 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx268,516,647 - 68,749,894 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0266,636,963 - 66,872,612 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0261,638,440 - 61,874,092 (-)NCBIRnor_WKY
Rnor_6.0262,399,748 - 62,520,448 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl262,399,748 - 62,634,785 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0282,168,243 - 82,288,609 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4261,828,127 - 61,953,671 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1261,756,359 - 61,864,415 (-)NCBI
Celera257,076,815 - 57,309,194 (+)NCBICelera
Cytogenetic Map2q16NCBI
PDZD2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38531,639,131 - 32,110,932 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl531,639,131 - 32,110,932 (+)EnsemblGRCh38hg38GRCh38
GRCh37531,639,238 - 32,111,038 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36531,834,788 - 32,146,795 (+)NCBINCBI36Build 36hg18NCBI36
Build 34531,675,273 - 32,146,795NCBI
Celera531,679,264 - 31,992,328 (+)NCBICelera
Cytogenetic Map5p13.3NCBI
HuRef531,766,346 - 32,078,169 (+)NCBIHuRef
CHM1_1531,800,063 - 32,112,328 (+)NCBICHM1_1
T2T-CHM13v2.0531,752,824 - 32,224,543 (+)NCBIT2T-CHM13v2.0
Pdzd2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391512,359,797 - 12,740,052 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1512,359,797 - 12,740,010 (-)EnsemblGRCm39 Ensembl
GRCm381512,359,711 - 12,739,968 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1512,359,711 - 12,739,924 (-)EnsemblGRCm38mm10GRCm38
MGSCv371512,286,809 - 12,522,311 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361512,301,779 - 12,684,649 (-)NCBIMGSCv36mm8
Celera1512,136,823 - 12,373,640 (-)NCBICelera
Cytogenetic Map15A1NCBI
Pdzd2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542617,600,571 - 17,974,914 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542617,600,722 - 17,974,916 (+)NCBIChiLan1.0ChiLan1.0
PDZD2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1583,611,687 - 84,079,810 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl583,614,460 - 83,921,415 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0578,229,681 - 78,701,213 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PDZD2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1475,336,023 - 75,564,980 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl475,338,791 - 75,564,599 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha474,972,179 - 75,330,536 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0475,855,009 - 76,258,330 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl475,855,011 - 76,258,296 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1475,593,378 - 75,951,613 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0475,723,219 - 76,081,215 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0476,251,243 - 76,609,516 (-)NCBIUU_Cfam_GSD_1.0
Pdzd2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024407213222,362,795 - 222,724,538 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365188,646,838 - 9,008,767 (-)EnsemblSpeTri2.0
SpeTri2.0NW_0049365188,647,338 - 8,883,494 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PDZD2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.11617,940,113 - 18,355,540 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21619,030,168 - 19,172,176 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PDZD2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1430,920,855 - 31,397,578 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl431,177,342 - 31,398,635 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607121,144,870 - 21,622,475 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pdzd2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475922,411,491 - 22,677,911 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475922,408,934 - 22,677,825 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Pdzd2
2675 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:114
Count of miRNA genes:92
Interacting mature miRNAs:98
Transcripts:ENSRNOT00000017937
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1298074Bp164Blood pressure QTL 1640.003arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)242804607202447032Rat
1298085Bp165Blood pressure QTL 1650.0006arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)242804607202447032Rat
5684990Bmd82Bone mineral density QTL 822.8tibia mineral mass (VT:1000283)bone mineral content (CMO:0001554)259324377103795077Rat
5684996Bmd85Bone mineral density QTL 854.70.024tibia mineral mass (VT:1000283)bone mineral density (CMO:0001226)259324377103795077Rat
6480225Gdil1Gastrointestinal dilation QTL 1enteric ganglion morphology trait (VT:0001045)length of intestine affected by colonic aganglionosis to total length of colon ratio (CMO:0001836)25666087974786777Rat
631500Bp99Blood pressure QTL 992.5arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)259324719102755241Rat
9590095Sffal3Serum free fatty acids level QTL 36.780.001blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)22715716072157160Rat
1331760Bp206Blood pressure QTL 2063.62454arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)256043031202447032Rat
10402051Gdil2Gastrointestinal dilation QTL 2enteric ganglion morphology trait (VT:0001045)length of intestine affected by colonic aganglionosis to total length of colon ratio (CMO:0001836)22490385374786777Rat
1302794Stl27Serum triglyceride level QTL 274.40.0001blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)225413423143657569Rat
1354592Rf50Renal function QTL 503.5urine output (VT:0003620)timed urine volume (CMO:0000260)25382274774786777Rat
1354601Slep1Serum leptin concentration QTL 15.39blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)243171017184114403Rat
1354603Bp243Blood pressure QTL 2433.9arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)226917817127469484Rat
1354617Bp240Blood pressure QTL 2404arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)22691781781754745Rat
1354617Bp240Blood pressure QTL 2404arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)22691781781754745Rat
1354617Bp240Blood pressure QTL 2404arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)22691781781754745Rat
1558648Smcn1Smooth muscle cell number QTL 10.039blood vessel smooth muscle cell quantity (VT:0010525)aorta smooth muscle cell count per unit vessel length (CMO:0001646)259134147127460910Rat
1357990Ael1Aortic elastin QTL 13.10.00091aorta elastin amount (VT:0003905)aortic elastin21907682564076825Rat
1578777Stresp15Stress response QTL 1520.05blood aldosterone amount (VT:0005346)plasma aldosterone level (CMO:0000551)259846005104846005Rat
61371Edpm1Estrogen-dependent pituitary mass QTL 140.05pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)23513484188029593Rat
61438Cia7Collagen induced arthritis QTL 74.60.0001joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)259324377141596857Rat
2290453Scl55Serum cholesterol level QTL 552.83blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)226917817136917119Rat
631208Bw1Body weight QTL15.09mesenteric fat pad mass (VT:0010427)mesenteric fat pad weight to body weight ratio (CMO:0000654)24317101783575226Rat
631266Bp132Blood pressure QTL 1320.0005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)246123260202447032Rat
61467Bp14Blood pressure QTL 142.2arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)243154682202446871Rat
61467Bp14Blood pressure QTL 142.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)243154682202446871Rat
2293835Kiddil5Kidney dilation QTL 53.8kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)242804607157142209Rat
2293843Kiddil6Kidney dilation QTL 63.1kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)242804607182042367Rat
2293671Bss44Bone structure and strength QTL 4410.970.0001lumbar vertebra morphology trait (VT:0010494)lumbar vertebra cortical cross-sectional area (CMO:0001690)243162366148478373Rat
1358899Kidm23Kidney mass QTL 233.88kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)225413423157142209Rat
61355Bp36Blood pressure QTL 362.9blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)25873687102844969Rat
1358911Kidm28Kidney mass QTL 285.42kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)225413423157142209Rat
10755436Coatc8Coat color QTL 80.02431coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)23502311780023117Rat
2293676Bmd19Bone mineral density QTL 1910.70.0001femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)243162366111362592Rat
1358894Kidm24Kidney mass QTL 244.03kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)225413423157142209Rat
1358904Cm39Cardiac mass QTL 392.26heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)225413423157142209Rat
1358908Bw49Body weight QTL 493.36body mass (VT:0001259)body weight (CMO:0000012)225413652157142078Rat
10755434Coatc7Coat color QTL 70.04794coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)23064806575648065Rat
2293682Bmd24Bone mineral density QTL 248.90.0001femur mineral mass (VT:0010011)cortical volumetric bone mineral density (CMO:0001730)243162366111362592Rat
1582246Cm60Cardiac mass QTL 605.8heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)25760561276539510Rat
731184Mamtr4Mammary tumor resistance QTL 40.0003mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)21649174061491740Rat
1358901Cm38Cardiac mass QTL 382heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)225413423157142209Rat
1358917Cm42Cardiac mass QTL 422.82heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)225413423203928301Rat
70174BpQTLCluster2Blood pressure QTL cluster 24.24arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)240067944102785628Rat
70174BpQTLCluster2Blood pressure QTL cluster 24.24arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)240067944102785628Rat
70174BpQTLCluster2Blood pressure QTL cluster 24.24arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)240067944102785628Rat
70174BpQTLCluster2Blood pressure QTL cluster 24.24arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)240067944102785628Rat
70174BpQTLCluster2Blood pressure QTL cluster 24.24arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)240067944102785628Rat
2300168Bmd47Bone mineral density QTL 476.60.0001femur mineral mass (VT:0010011)bone mineral density (CMO:0001226)22066244865662448Rat
731167Glom4Glomerulus QTL 42.40.0082kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)22030467265304672Rat
1358910Kidm27Kidney mass QTL 275.77kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)225413423157142209Rat
1358913Cm41Cardiac mass QTL 412.73heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)225413423203928301Rat
1358887Bw50Body weight QTL 502.39body mass (VT:0001259)body weight (CMO:0000012)225413652157142078Rat

Markers in Region
D2Mit4  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2261,582,123 - 61,582,311 (+)MAPPERmRatBN7.2
Rnor_6.0262,594,946 - 62,595,133NCBIRnor6.0
Rnor_5.0282,093,558 - 82,093,745UniSTSRnor5.0
Celera257,114,745 - 57,114,932UniSTS
RH 2.0 Map2346.3RGD
Cytogenetic Map2q16UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 24 23 22 18 11
Low 3 19 55 39 19 39 8 11 51 13 23 8
Below cutoff 2 2 2

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_022940 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039103085 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039103086 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039103087 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039103088 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039103089 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039103090 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039103091 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039103092 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039103093 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039103094 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039103095 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC095678 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF169411 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC089934 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH474058 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JACYVU010000066 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000017937   ⟹   ENSRNOP00000017937
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl261,386,381 - 61,706,526 (-)Ensembl
Rnor_6.0 Ensembl262,399,748 - 62,634,785 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000093934   ⟹   ENSRNOP00000087015
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl261,620,225 - 61,650,100 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000105047   ⟹   ENSRNOP00000079233
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl261,386,381 - 61,770,524 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000108989   ⟹   ENSRNOP00000093111
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl261,386,381 - 61,770,524 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000112645   ⟹   ENSRNOP00000091337
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl261,386,381 - 61,770,524 (-)Ensembl
RefSeq Acc Id: NM_022940   ⟹   NP_075229
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2261,387,026 - 61,621,146 (-)NCBI
Rnor_6.0262,399,748 - 62,520,448 (-)NCBI
Rnor_5.0282,168,243 - 82,288,609 (+)NCBI
RGSC_v3.4261,828,127 - 61,953,671 (-)RGD
Celera257,076,815 - 57,309,194 (+)RGD
Sequence:
RefSeq Acc Id: XM_039103085   ⟹   XP_038959013
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2261,384,614 - 61,770,509 (-)NCBI
RefSeq Acc Id: XM_039103086   ⟹   XP_038959014
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2261,384,614 - 61,770,509 (-)NCBI
RefSeq Acc Id: XM_039103087   ⟹   XP_038959015
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2261,384,614 - 61,650,068 (-)NCBI
RefSeq Acc Id: XM_039103088   ⟹   XP_038959016
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2261,384,614 - 61,650,215 (-)NCBI
RefSeq Acc Id: XM_039103089   ⟹   XP_038959017
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2261,384,614 - 61,770,509 (-)NCBI
RefSeq Acc Id: XM_039103090   ⟹   XP_038959018
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2261,384,614 - 61,770,510 (-)NCBI
RefSeq Acc Id: XM_039103091   ⟹   XP_038959019
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2261,384,614 - 61,770,510 (-)NCBI
RefSeq Acc Id: XM_039103092   ⟹   XP_038959020
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2261,384,614 - 61,578,768 (-)NCBI
RefSeq Acc Id: XM_039103093   ⟹   XP_038959021
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2261,384,614 - 61,529,556 (-)NCBI
RefSeq Acc Id: XM_039103094   ⟹   XP_038959022
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2261,384,614 - 61,490,203 (-)NCBI
RefSeq Acc Id: XM_039103095   ⟹   XP_038959023
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2261,401,057 - 61,770,516 (-)NCBI
Reference Sequences
RefSeq Acc Id: NP_075229   ⟸   NM_022940
- UniProtKB: A0A8I6AIY0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000017937   ⟸   ENSRNOT00000017937
RefSeq Acc Id: XP_038959019   ⟸   XM_039103091
- Peptide Label: isoform X4
RefSeq Acc Id: XP_038959018   ⟸   XM_039103090
- Peptide Label: isoform X3
RefSeq Acc Id: XP_038959017   ⟸   XM_039103089
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038959013   ⟸   XM_039103085
- Peptide Label: isoform X1
- UniProtKB: A0A8I5ZMB2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038959014   ⟸   XM_039103086
- Peptide Label: isoform X1
- UniProtKB: A0A8I5ZMB2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038959016   ⟸   XM_039103088
- Peptide Label: isoform X1
- UniProtKB: A0A8I5ZMB2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038959015   ⟸   XM_039103087
- Peptide Label: isoform X1
- UniProtKB: A0A8I5ZMB2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038959020   ⟸   XM_039103092
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038959021   ⟸   XM_039103093
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038959022   ⟸   XM_039103094
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038959023   ⟸   XM_039103095
- Peptide Label: isoform X6
RefSeq Acc Id: ENSRNOP00000093111   ⟸   ENSRNOT00000108989
RefSeq Acc Id: ENSRNOP00000087015   ⟸   ENSRNOT00000093934
RefSeq Acc Id: ENSRNOP00000079233   ⟸   ENSRNOT00000105047
RefSeq Acc Id: ENSRNOP00000091337   ⟸   ENSRNOT00000112645
Protein Domains
PDZ

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:619958 AgrOrtholog
BioCyc Gene G2FUF-54042 BioCyc
Ensembl Genes ENSRNOG00000013140 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000017937.4 UniProtKB/TrEMBL
  ENSRNOP00000079233 ENTREZGENE
  ENSRNOP00000079233.1 UniProtKB/TrEMBL
  ENSRNOP00000087015.1 UniProtKB/TrEMBL
  ENSRNOP00000091337.1 UniProtKB/TrEMBL
  ENSRNOP00000093111 ENTREZGENE
  ENSRNOP00000093111.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000017937.4 UniProtKB/TrEMBL
  ENSRNOT00000093934.1 UniProtKB/TrEMBL
  ENSRNOT00000105047 ENTREZGENE
  ENSRNOT00000105047.1 UniProtKB/TrEMBL
  ENSRNOT00000108989 ENTREZGENE
  ENSRNOT00000108989.1 UniProtKB/TrEMBL
  ENSRNOT00000112645.1 UniProtKB/TrEMBL
Gene3D-CATH 2.30.42.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro PDZ UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PDZ_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:65034 UniProtKB/Swiss-Prot
NCBI Gene 65034 ENTREZGENE
Pfam PDZ UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Pdzd2 PhenoGen
PROSITE PDZ UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART PDZ UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF50156 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I5ZMB2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6A3J1_RAT UniProtKB/TrEMBL
  A0A8I6ABF3_RAT UniProtKB/TrEMBL
  A0A8I6AIY0 ENTREZGENE, UniProtKB/TrEMBL
  F1M785_RAT UniProtKB/TrEMBL
  PDZD2_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Pdzd2  PDZ domain containing 2  LOC102546845  uncharacterized LOC102546845  Data Merged 737654 PROVISIONAL
2013-12-18 LOC102546845  uncharacterized LOC102546845      Symbol and Name status set to provisional 70820 PROVISIONAL
2008-02-22 Pdzd2  PDZ domain containing 2  Pdzk3  PDZ domain containing 3  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-20 Pdzk3  PDZ domain containing 3  Papin  PAPIN  Symbol and Name updated 1299863 APPROVED
2002-08-07 Papin  PAPIN      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_domains contains multiple PDZ domains 633698
gene_expression expressed ubiquitously 633698
gene_physical_interaction bind s to E-cadherin and beta-catenin 633698