Rps15a (ribosomal protein S15a) - Rat Genome Database

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Gene: Rps15a (ribosomal protein S15a) Rattus norvegicus
Analyze
Symbol: Rps15a
Name: ribosomal protein S15a
RGD ID: 619939
Description: Predicted to be a structural constituent of ribosome. Predicted to be involved in several processes, including positive regulation of cell population proliferation; response to virus; and ribosomal small subunit biogenesis. Part of cytosolic small ribosomal subunit. Human ortholog(s) of this gene implicated in Diamond-Blackfan anemia 20. Orthologous to human RPS15A (ribosomal protein S15a); PARTICIPATES IN ribosome biogenesis pathway; translation pathway; INTERACTS WITH 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: 40S ribosomal protein S15a; small ribosomal subunit protein uS8
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Related Pseudogenes: Rps15a-ps8   Rps15a-ps9  
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81181,854,396 - 181,861,330 (-)NCBIGRCr8
mRatBN7.21172,420,151 - 172,427,021 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1172,419,761 - 172,426,995 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1180,725,320 - 180,731,219 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01187,911,648 - 187,917,547 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01180,641,429 - 180,647,328 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01187,759,865 - 187,766,734 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1187,759,480 - 187,766,709 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01194,713,988 - 194,720,867 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41176,321,901 - 176,327,789 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11176,461,146 - 176,467,032 (-)NCBI
Celera1170,206,665 - 170,212,554 (-)NCBICelera
Cytogenetic Map1q35NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane  (EXP)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (EXP)
17beta-estradiol  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,3,7,8-Tetrachlorodibenzofuran  (EXP)
2,4,6-tribromophenol  (ISO)
2,4,6-trinitrotoluene  (EXP)
2,4-dinitrobenzenesulfonic acid  (ISO)
2,6-dinitrotoluene  (EXP)
2-hydroxypropanoic acid  (ISO)
2-nitrofluorene  (EXP)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3,3'-diindolylmethane  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (EXP,ISO)
4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one  (EXP)
acrolein  (ISO)
acrylamide  (ISO)
aflatoxin B1  (EXP,ISO)
all-trans-retinoic acid  (ISO)
alpha-pinene  (ISO)
ammonium chloride  (EXP)
antirheumatic drug  (ISO)
aristolochic acids  (EXP)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
artesunate  (ISO)
benzo[a]pyrene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP,ISO)
carbon nanotube  (ISO)
chromium(6+)  (ISO)
clobetasol  (ISO)
clofibric acid  (EXP)
decabromodiphenyl ether  (ISO)
dextran sulfate  (ISO)
diarsenic trioxide  (ISO)
dicrotophos  (ISO)
diethylstilbestrol  (EXP)
diuron  (EXP)
dorsomorphin  (ISO)
entinostat  (ISO)
epoxiconazole  (ISO)
ethanol  (ISO)
flavonoids  (EXP)
flutamide  (EXP)
folic acid  (ISO)
furan  (EXP)
gentamycin  (EXP)
hydrogen peroxide  (ISO)
indometacin  (EXP)
ivermectin  (ISO)
lead(0)  (ISO)
leflunomide  (ISO)
methapyrilene  (EXP)
methylmercury chloride  (ISO)
methylparaben  (ISO)
N-nitrosodiethylamine  (EXP)
N-nitrosodimethylamine  (EXP)
nimesulide  (EXP)
ochratoxin A  (EXP)
ozone  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
phenanthrene  (ISO)
phenylmercury acetate  (ISO)
piperonyl butoxide  (EXP)
pirinixic acid  (EXP)
pregnenolone 16alpha-carbonitrile  (ISO)
rac-lactic acid  (ISO)
SB 431542  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenite  (EXP,ISO)
sodium fluoride  (EXP,ISO)
sunitinib  (ISO)
tetrachloromethane  (EXP)
thapsigargin  (EXP)
thiram  (ISO)
tolcapone  (EXP)
trichostatin A  (ISO)
triphenyl phosphate  (ISO)
triptonide  (ISO)
tungsten  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Structures of the human and Drosophila 80S ribosome. Anger AM, etal., Nature. 2013 May 2;497(7447):80-5. doi: 10.1038/nature12104.
2. The primary structure of rat ribosomal protein S15a. Chan YL, etal., Biochem Biophys Res Commun 1994 May 16;200(3):1498-504.
3. Isolation of eukaryotic ribosomal proteins. Purification and characterization of the 40 S ribosomal subunit proteins Sa, Sc, S3a, S3b, S5', S9, S10, S11, S12, S14, S15, S15', S16, S17, S18, S19, S20, S21, S26, S27', and S29. Collatz E, etal., J Biol Chem. 1977 Dec 25;252(24):9071-80.
4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
5. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
6. Functional dichotomy of ribosomal proteins during the synthesis of mammalian 40S ribosomal subunits. O'Donohue MF, etal., J Cell Biol. 2010 Sep 6;190(5):853-66. doi: 10.1083/jcb.201005117.
7. GOA pipeline RGD automated data pipeline
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Comprehensive gene review and curation RGD comprehensive gene curation
10. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:8706699   PMID:15108328   PMID:15489334   PMID:15883184   PMID:18614015   PMID:19946888   PMID:20458337   PMID:22658674   PMID:22681889   PMID:23376485   PMID:23979707   PMID:24625528  
PMID:25931508   PMID:35352799   PMID:37094854  


Genomics

Comparative Map Data
Rps15a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81181,854,396 - 181,861,330 (-)NCBIGRCr8
mRatBN7.21172,420,151 - 172,427,021 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1172,419,761 - 172,426,995 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1180,725,320 - 180,731,219 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01187,911,648 - 187,917,547 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01180,641,429 - 180,647,328 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01187,759,865 - 187,766,734 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1187,759,480 - 187,766,709 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01194,713,988 - 194,720,867 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41176,321,901 - 176,327,789 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11176,461,146 - 176,467,032 (-)NCBI
Celera1170,206,665 - 170,212,554 (-)NCBICelera
Cytogenetic Map1q35NCBI
RPS15A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381618,781,295 - 18,790,334 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1618,781,295 - 18,790,383 (-)EnsemblGRCh38hg38GRCh38
GRCh371618,792,617 - 18,801,656 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361618,701,778 - 18,709,157 (-)NCBINCBI36Build 36hg18NCBI36
Build 341618,701,789 - 18,709,157NCBI
Celera1617,948,012 - 17,955,392 (-)NCBICelera
Cytogenetic Map16p12.3NCBI
HuRef1617,336,473 - 17,343,840 (-)NCBIHuRef
CHM1_11618,881,758 - 18,889,137 (-)NCBICHM1_1
T2T-CHM13v2.01618,717,732 - 18,726,769 (-)NCBIT2T-CHM13v2.0
Rps15a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397117,703,597 - 117,715,370 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl7117,703,595 - 117,715,411 (-)EnsemblGRCm39 Ensembl
GRCm387118,104,374 - 118,116,147 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7118,104,372 - 118,116,188 (-)EnsemblGRCm38mm10GRCm38
MGSCv377125,247,888 - 125,259,661 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv367117,895,523 - 117,907,296 (-)NCBIMGSCv36mm8
Celera7118,055,217 - 118,066,974 (-)NCBICelera
Cytogenetic Map7F1NCBI
cM Map763.44NCBI
Rps15a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554422,530,838 - 2,535,421 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554422,530,838 - 2,535,421 (-)NCBIChiLan1.0ChiLan1.0
RPS15A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21820,052,844 - 20,060,605 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11624,576,291 - 24,583,598 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01619,489,898 - 19,497,202 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
RPS15A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1626,322,478 - 26,329,529 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl626,322,569 - 26,329,668 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha627,688,370 - 27,695,424 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0626,482,742 - 26,489,790 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl626,482,845 - 26,495,915 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1626,281,670 - 26,288,712 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0626,177,362 - 26,184,407 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0626,566,174 - 26,573,227 (+)NCBIUU_Cfam_GSD_1.0
Rps15a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344116,552,972 - 116,558,411 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365014,650,062 - 4,656,236 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365014,650,832 - 4,656,223 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RPS15A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl326,776,780 - 26,784,124 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1326,776,661 - 26,783,491 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
RPS15A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1517,082,307 - 17,100,719 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl517,082,137 - 17,100,780 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606812,846,296 - 12,853,595 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rps15a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247822,231,281 - 2,236,035 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247822,231,281 - 2,236,078 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Rps15a
20 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:54
Count of miRNA genes:49
Interacting mature miRNAs:53
Transcripts:ENSRNOT00000024678
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10059597Bp377Blood pressure QTL 3773.420.025arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)132737458199368955Rat
634314Niddm44Non-insulin dependent diabetes mellitus QTL 44blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)149393289199050459Rat
1578780Cm52Cardiac mass QTL 523.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)181591954219808434Rat
724521Uae1Urinary albumin excretion QTL 13.80.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)190508614173018436Rat
1358902Bw47Body weight QTL 471.67body mass (VT:0001259)body weight (CMO:0000012)190508614180359386Rat
1331793Bp200Blood pressure QTL 2003.71601arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)194494440172949803Rat
1331751Bp199Blood pressure QTL 1993.60022arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)194494440181830018Rat
1331749Hrtrt11Heart rate QTL 112.973heart pumping trait (VT:2000009)heart rate (CMO:0000002)194494440198211706Rat
70209Niddm23Non-insulin dependent diabetes mellitus QTL 232.82blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)194494440198324465Rat
731168Bp154Blood pressure QTL 1543.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)194642644214537671Rat
8655649Arrd1Age-related retinal degeneration QTL 14.89retinal layer morphology trait (VT:0003727)percentage of study population developing retinopathy during a period of time (CMO:0002453)1100357752183970443Rat
1354591Cm36Cardiac mass QTL 364.1heart left ventricle mass (VT:0007031)calculated heart weight (CMO:0000073)1102813953201278233Rat
1354615Cm32Cardiac mass QTL 325.2heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)1102813953201278233Rat
1354606Bp246Blood pressure QTL 2463.6arterial blood pressure trait (VT:2000000)pulse pressure (CMO:0000292)1102813953218753816Rat
1300158Bp173Blood pressure QTL 1733.48arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)1115540693185145286Rat
7794788Mcs32Mammary carcinoma susceptibility QTL 322.61mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)1115540693238914717Rat
631199Cm23Cardiac mass QTL 234.60.0004heart left ventricle mass (VT:0007031)heart left ventricle wet weight (CMO:0000071)1115585465172949803Rat
7421630Bp362Blood pressure QTL 3620.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1118608292241799120Rat
631205Bp196Blood pressure QTL 19640.0001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1118944897199050459Rat
631544Bp84Blood pressure QTL 845.6arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1123350408181759564Rat
1358189Cstrr1Cold stress response QTL 10.0001catecholamine amount (VT:0010543)urine norepinephrine level (CMO:0001629)1123350408182418476Rat
1641895Bp298Blood pressure QTL 298arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1123350408182418476Rat
1578770Stresp23Stress response QTL 23kidney sympathetic nerve activity (VT:0004050)stimulated renal sympathetic nerve activity to basal renal sympathetic nerve activity ratio (CMO:0001786)1123350408182418476Rat
631549Bp89Blood pressure QTL 895.7arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1123350581201284552Rat
738006Anxrr14Anxiety related response QTL 1440.00035locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)1130636910175636910Rat
738028Anxrr12Anxiety related response QTL 124.90.00001locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)1130636910175636910Rat
6893347Bw98Body weight QTL 980.20.53body mass (VT:0001259)body weight (CMO:0000012)1133680936178680936Rat
6893361Bw104Body weight QTL 1040.590.27body mass (VT:0001259)body weight (CMO:0000012)1133680936178680936Rat
1558645Bw55Body weight QTL 553.20.004body mass (VT:0001259)body weight (CMO:0000012)1133680936178680936Rat
71118Thym1Thymus enlargement QTL 110.170.001thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)1136829932181829932Rat
724550Thym3Thymus enlargement QTL 37.820.001thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)1136829932181829932Rat
631519Pia11Pristane induced arthritis QTL 115.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1136830018181830018Rat
1598853Memor3Memory QTL 34.5exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)1143506580212458660Rat
61348Bp30Blood pressure QTL 302.4arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1144017057197814409Rat
70160Bw18Body weight QTL 185.7body mass (VT:0001259)body weight (CMO:0000012)1144267353196383668Rat
737828Hcas3Hepatocarcinoma susceptibility QTL 34.9liver integrity trait (VT:0010547)liver tumorous lesion volume to total liver volume ratio (CMO:0001082)1144267353222987745Rat
2302378Insul11Insulin level QTL 113.25blood insulin amount (VT:0001560)serum insulin level (CMO:0000358)1144267353251128347Rat
634315Niddm45Non-insulin dependent diabetes mellitus QTL 457.16blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)1144267916172949660Rat
61379Bp44Blood pressure QTL 4419.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1144267916174133260Rat
7771612Cm80Cardiac mass QTL 808.4heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)1149448574221264292Rat
724531Uae5Urinary albumin excretion QTL 54urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)1150700142252085212Rat
1578759Uae30Urinary albumin excretion QTL 303.30.003urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1150700247252085048Rat
1578778Pur4Proteinuria QTL 43.30.003urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)1150700247252085048Rat
1354602Bw35Body weight QTL 3512.2body mass (VT:0001259)body weight (CMO:0000012)1151162512201278233Rat
1354620Kidm19Kidney mass QTL 194kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1151162512201278233Rat
1354634Kidm12Kidney mass QTL 123.9kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)1151162512201278233Rat
1354636Lmblg1Limb length QTL 16.4tibia length (VT:0004357)tibia length (CMO:0000450)1151162512201278233Rat
1354610Bw34Body weight QTL 344.1body mass (VT:0001259)body weight (CMO:0000012)1151162512256448636Rat
1354646Kidm18Kidney mass QTL 185.7kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)1151162512256448636Rat
1354661Bw33Body weight QTL 335.2body mass (VT:0001259)body weight (CMO:0000012)1151162512256448636Rat
1358886Bp260Blood pressure QTL 2603.67arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1151162766225824951Rat
61343Bp28Blood pressure QTL 28arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1151646613196646613Rat
1549837Hcar15Hepatocarcinoma resistance QTL 150.05liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)1153136852260522016Rat
2303622Vencon6Ventilatory control QTL 60.001respiration trait (VT:0001943)respiration rate (CMO:0000289)1154561505199561505Rat
1582204Livw1Liver weight QTL 13.60.0003liver mass (VT:0003402)liver weight to body weight ratio (CMO:0000633)1155422851172949803Rat
4889428Stresp24Stress response QTL 240.05heart pumping trait (VT:2000009)absolute change in electrocardiographic low frequency R-R spectral component to high frequency R-R spectral component ratio (CMO:0002162)1155866514200866514Rat
631548Bp88Blood pressure QTL 8850.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1156677124176484451Rat
1354618Kidm15Kidney mass QTL 155kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)1156677124201278233Rat
2312420Pur17Proteinuria QTL 177.10.0001urine protein amount (VT:0005160)urine total protein excretion rate (CMO:0000756)1156677124218753816Rat
1354580Scort1Serum corticosterone level QTL 13.4blood corticosterone amount (VT:0005345)blood corticosterone level (CMO:0001172)1156677124256448636Rat
61347Bp197Blood pressure QTL 1974.2arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)1158633083203633083Rat
2292222Bp307Blood pressure QTL 3073.060.0014arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1164310393213533942Rat
2292220Bp306Blood pressure QTL 3063.470.00087arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1164310393243914901Rat
619613Bp77Blood pressure QTL 770.01arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1164747424209747424Rat
619613Bp77Blood pressure QTL 770.01arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)1164747424209747424Rat
737974Bp161Blood pressure QTL 1610.002arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1164747558181133855Rat
2312558Glom17Glomerulus QTL 173.90.001kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)1166532971191278129Rat
1354653Despr9Despair related QTL 90.00019locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)1167909849212909849Rat
619614Bp78Blood pressure QTL 780.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1169112897197261052Rat
619614Bp78Blood pressure QTL 780.001arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)1169112897197261052Rat
61341Bp26Blood pressure QTL 26arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1169537671214537671Rat
724562Rends1Renal damage susceptibility QTL 10.05kidney glomerulus integrity trait (VT:0010546)index of glomerular damage (CMO:0001135)1169537671214537671Rat
1358294Bw37Body weight QTL 3750.000011body mass (VT:0001259)body weight (CMO:0000012)1171310381216310381Rat
2293689Bss47Bone structure and strength QTL 477.250.0001lumbar vertebra size trait (VT:0010518)lumbar vertebra trabecular cross-sectional area (CMO:0001692)1171629477216629477Rat
2293693Bss22Bone structure and strength QTL 2233.520.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)1171629477216629477Rat
2300161Bmd43Bone mineral density QTL 438.40.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)1171629477216629477Rat
2300174Bmd42Bone mineral density QTL 428.40.0001lumbar vertebra mineral mass (VT:0010511)bone mineral density (CMO:0001226)1171629477216629477Rat
2300187Bmd41Bone mineral density QTL 418.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)1171629477216629477Rat
2293654Bss30Bone structure and strength QTL 3032.650.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)1171629477216629477Rat
2293673Bss27Bone structure and strength QTL 2718.630.0001femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)1171629477216629477Rat
2293677Bss41Bone structure and strength QTL 419.380.0001lumbar vertebra size trait (VT:0010518)lumbar vertebra cross-sectional area (CMO:0001689)1171629477216629477Rat

Markers in Region
RH128261  
Rat AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map1q35UniSTS
Cytogenetic Map8q24UniSTS
RH131675  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21172,419,890 - 172,420,071 (+)MAPPERmRatBN7.2
Rnor_6.01187,759,605 - 187,759,785NCBIRnor6.0
Rnor_5.01194,713,738 - 194,713,918UniSTSRnor5.0
RGSC_v3.41176,321,641 - 176,321,821UniSTSRGSC3.4
Celera1170,206,405 - 170,206,585UniSTS
RH 3.4 Map11563.6UniSTS
Cytogenetic Map1q35UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High 2 3 2
Medium 1 43 57 41 16 41 8 11 74 35 41 9 8
Low
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_053982 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006230097 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006230098 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039112732 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039112774 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide BC058452 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473956 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ210209 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ211215 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ212042 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ212257 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ214481 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ220418 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ220927 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ220997 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ221041 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ221112 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ221144 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ221174 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ221230 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ221308 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ221419 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ221518 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ221677 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ221720 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ221825 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ221840 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ221877 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ222252 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ222272 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ222274 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ222304 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ222376 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ222415 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ222418 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ222718 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ222721 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ222768 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ222892 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ222921 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ222922 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ223006 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ223095 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ223230 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ223341 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ223389 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ223433 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ223787 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ223822 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ223930 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ224201 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ224347 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ224383 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ228419 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ228429 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ228446 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ228475 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ228508 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ228609 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ228617 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ229004 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ229042 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ229063 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000001 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X77953 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENSRNOT00000024678   ⟹   ENSRNOP00000024678
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1187,759,901 - 187,765,744 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000092282   ⟹   ENSRNOP00000075906
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1172,419,761 - 172,426,995 (-)Ensembl
Rnor_6.0 Ensembl1187,759,480 - 187,766,709 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000092316
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1187,764,778 - 187,766,690 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000092513   ⟹   ENSRNOP00000075747
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1172,425,531 - 172,426,957 (-)Ensembl
Rnor_6.0 Ensembl1187,759,865 - 187,766,670 (-)Ensembl
RefSeq Acc Id: NM_053982   ⟹   NP_446434
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81181,854,396 - 181,860,284 (-)NCBI
mRatBN7.21172,420,151 - 172,426,040 (-)NCBI
Rnor_6.01187,759,865 - 187,765,753 (-)NCBI
Rnor_5.01194,713,988 - 194,720,867 (-)NCBI
RGSC_v3.41176,321,901 - 176,327,789 (-)RGD
Celera1170,206,665 - 170,212,554 (-)RGD
Sequence:
RefSeq Acc Id: XM_006230097   ⟹   XP_006230159
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81181,854,396 - 181,861,330 (-)NCBI
mRatBN7.21172,420,151 - 172,427,021 (-)NCBI
Rnor_6.01187,759,865 - 187,766,734 (-)NCBI
Rnor_5.01194,713,988 - 194,720,867 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006230098   ⟹   XP_006230160
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81181,854,396 - 181,861,239 (-)NCBI
mRatBN7.21172,420,151 - 172,426,970 (-)NCBI
Rnor_6.01187,759,865 - 187,766,670 (-)NCBI
Rnor_5.01194,713,988 - 194,720,867 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039112732   ⟹   XP_038968660
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81181,854,396 - 181,861,218 (-)NCBI
mRatBN7.21172,420,151 - 172,426,974 (-)NCBI
RefSeq Acc Id: XM_039112774   ⟹   XP_038968702
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81181,854,396 - 181,861,054 (-)NCBI
mRatBN7.21172,420,151 - 172,426,527 (-)NCBI
RefSeq Acc Id: NP_446434   ⟸   NM_053982
- UniProtKB: P62246 (UniProtKB/Swiss-Prot),   A6I8G0 (UniProtKB/TrEMBL),   A0A0G2JYA6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006230159   ⟸   XM_006230097
- Peptide Label: isoform X1
- UniProtKB: P62246 (UniProtKB/Swiss-Prot),   A6I8G0 (UniProtKB/TrEMBL),   A0A0G2JYA6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006230160   ⟸   XM_006230098
- Peptide Label: isoform X1
- UniProtKB: P62246 (UniProtKB/Swiss-Prot),   A6I8G0 (UniProtKB/TrEMBL),   A0A0G2JYA6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000075906   ⟸   ENSRNOT00000092282
RefSeq Acc Id: ENSRNOP00000075747   ⟸   ENSRNOT00000092513
RefSeq Acc Id: ENSRNOP00000024678   ⟸   ENSRNOT00000024678
RefSeq Acc Id: XP_038968660   ⟸   XM_039112732
- Peptide Label: isoform X1
- UniProtKB: P62246 (UniProtKB/Swiss-Prot),   A6I8G0 (UniProtKB/TrEMBL),   A0A0G2JYA6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038968702   ⟸   XM_039112774
- Peptide Label: isoform X1
- UniProtKB: P62246 (UniProtKB/Swiss-Prot),   A6I8G0 (UniProtKB/TrEMBL),   A0A0G2JYA6 (UniProtKB/TrEMBL)

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P62246-F1-model_v2 AlphaFold P62246 1-130 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13690343
Promoter ID:EPDNEW_R862
Type:initiation region
Name:Rps15a_1
Description:ribosomal protein S15a
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01187,766,676 - 187,766,736EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:619939 AgrOrtholog
BioCyc Gene G2FUF-57699 BioCyc
Ensembl Genes ENSRNOG00000018320 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSRNOG00000042940 UniProtKB/TrEMBL
  ENSRNOG00055006817 UniProtKB/Swiss-Prot
  ENSRNOG00060018117 UniProtKB/Swiss-Prot
  ENSRNOG00065029341 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000065156.4 UniProtKB/TrEMBL
  ENSRNOT00000092282.2 UniProtKB/Swiss-Prot
  ENSRNOT00000092513.2 UniProtKB/TrEMBL
  ENSRNOT00055011172 UniProtKB/Swiss-Prot
  ENSRNOT00060031073 UniProtKB/Swiss-Prot
  ENSRNOT00065050678 UniProtKB/Swiss-Prot
Gene3D-CATH 3.30.1370.30 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.30.1490.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:6921126 IMAGE-MGC_LOAD
InterPro Ribosomal_S8 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ribosomal_S8_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ribosomal_uS8_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:117053 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE MGC:72730 IMAGE-MGC_LOAD
NCBI Gene 117053 ENTREZGENE
PANTHER 40S RIBOSOMAL PROTEIN S15A UniProtKB/Swiss-Prot
  40S RIBOSOMAL PROTEIN S15A UniProtKB/TrEMBL
  40S RIBOSOMAL PROTEIN S15A UniProtKB/TrEMBL
  PTHR11758 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Ribosomal_S8 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Rps15a PhenoGen
PROSITE RIBOSOMAL_S8 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000018320 RatGTEx
  ENSRNOG00000042940 RatGTEx
  ENSRNOG00055006817 RatGTEx
  ENSRNOG00060018117 RatGTEx
  ENSRNOG00065029341 RatGTEx
Superfamily-SCOP SSF56047 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0G2JYA6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8L2RAY2_RAT UniProtKB/TrEMBL
  A6I8G0 ENTREZGENE, UniProtKB/TrEMBL
  P62246 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary P39027 UniProtKB/Swiss-Prot
  P39031 UniProtKB/Swiss-Prot
  Q8C023 UniProtKB/Swiss-Prot
  Q9BV24 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2004-02-26 Rps15a  ribosomal protein S15a      Symbol and Name status set to approved 625702 APPROVED
2002-08-07 Rps15a  ribosomal protein S15a      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_other 10 to 15 copies of the gene 633990
gene_protein 129 amino acids 633990