Smc1a (structural maintenance of chromosomes 1A) - Rat Genome Database

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Gene: Smc1a (structural maintenance of chromosomes 1A) Rattus norvegicus
Analyze
Symbol: Smc1a
Name: structural maintenance of chromosomes 1A
RGD ID: 61991
Description: Predicted to enable several functions, including chromatin binding activity; mediator complex binding activity; and protein heterodimerization activity. Involved in meiotic cell cycle. Located in lateral element and nucleoplasm. Biomarker of type 2 diabetes mellitus. Human ortholog(s) of this gene implicated in Cornelia de Lange syndrome 2; congestive heart failure; and developmental and epileptic encephalopathy 85. Orthologous to human SMC1A (structural maintenance of chromosomes 1A); PARTICIPATES IN cell cycle pathway, mitotic; INTERACTS WITH 1,2-dimethylhydrazine; 1,3-dinitrobenzene; 17alpha-ethynylestradiol.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: DXhXs423e; KIAA0178; SB1.8; segregation of mitotic chromosomes-like 1; SMC (segregation of mitotic chromosomes 1)-like 1; SMC (segregation of mitotic chromosomes 1)-like 1 (yeast) ; SMC protein 1A; SMC-1A; SMC-like 1; SMC-like 1 (yeast) ; SMC-protein; Smc1l1; structural maintenance of chromosomes 1 like 1; structural maintenance of chromosomes 1 like 1 (S. cerevisiae); structural maintenance of chromosomes protein 1A
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X24,582,732 - 24,627,462 (+)NCBIGRCr8
mRatBN7.2X21,103,323 - 21,148,053 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX21,103,282 - 21,148,056 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX18,580,342 - 18,625,072 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X21,498,503 - 21,543,222 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X21,668,965 - 21,713,695 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X21,710,976 - 21,755,708 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX21,711,019 - 21,755,525 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X21,691,592 - 21,736,383 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X41,503,393 - 41,547,830 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1X41,556,861 - 41,601,299 (+)NCBI
CeleraX21,378,634 - 21,423,365 (+)NCBICelera
Cytogenetic MapXq13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (EXP,ISO)
1,3-dinitrobenzene  (EXP)
1-chloro-2,4-dinitrobenzene  (ISO)
17alpha-ethynylestradiol  (EXP,ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,3',4,4',5-Pentachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,6-dinitrotoluene  (EXP)
2-hydroxypropanoic acid  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4-(ethoxymethylene)-2-phenyloxazol-5-one  (ISO)
4-amino-2,6-dinitrotoluene  (EXP)
4-vinylcyclohexene dioxide  (ISO)
acrylamide  (ISO)
all-trans-retinoic acid  (ISO)
ammonium chloride  (EXP)
arecoline  (ISO)
Aroclor 1254  (ISO)
arsenite(3-)  (ISO)
benzo[a]pyrene  (ISO)
beta-lapachone  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
bleomycin A2  (ISO)
bortezomib  (ISO)
busulfan  (ISO)
butanal  (ISO)
Butylparaben  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
cannabidiol  (ISO)
CGP 52608  (ISO)
chromium(6+)  (ISO)
chrysene  (ISO)
clofarabine  (ISO)
cobalt dichloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
coumarin  (ISO)
coumestrol  (ISO)
deguelin  (ISO)
dicrotophos  (ISO)
dorsomorphin  (ISO)
doxorubicin  (ISO)
endosulfan  (EXP)
Enterolactone  (ISO)
finasteride  (EXP)
flavonoids  (EXP)
folic acid  (ISO)
FR900359  (ISO)
furan  (EXP)
geldanamycin  (ISO)
glyphosate  (ISO)
hydrogen peroxide  (ISO)
ivermectin  (ISO)
Lasiocarpine  (ISO)
lead(0)  (ISO)
linsidomine  (EXP)
lycopene  (ISO)
menadione  (ISO)
methapyrilene  (EXP)
methotrexate  (ISO)
methoxychlor  (ISO)
methylparaben  (ISO)
monocrotaline  (ISO)
myristicin  (ISO)
N-acetyl-L-cysteine  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
nickel atom  (ISO)
nickel sulfate  (ISO)
oxaliplatin  (EXP)
paracetamol  (ISO)
paraquat  (ISO)
pentanal  (ISO)
perfluorooctane-1-sulfonic acid  (EXP)
perfluorooctanoic acid  (ISO)
phenylmercury acetate  (ISO)
pirinixic acid  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
propanal  (ISO)
pyrimidifen  (ISO)
quercetin  (ISO)
rac-lactic acid  (ISO)
resveratrol  (EXP,ISO)
rotenone  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
sulindac  (EXP)
tebufenpyrad  (ISO)
thapsigargin  (EXP)
thimerosal  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
topotecan  (EXP)
torcetrapib  (ISO)
Tributyltin oxide  (ISO)
trichloroethene  (EXP)
trimellitic anhydride  (ISO)
triphenyl phosphate  (ISO)
troglitazone  (ISO)
tungsten  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)
vorinostat  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cohesin complex  (ISO)
cytosol  (IEA,ISO)
kinetochore  (IEA,ISO,ISS)
lateral element  (IDA)
meiotic cohesin complex  (IBA,IEA,ISO,ISS)
mitotic cohesin complex  (IEA,ISO)
mitotic spindle pole  (IEA,ISO)
nuclear matrix  (IEA,ISO)
nucleoplasm  (IDA,IEA,ISO)
nucleus  (IBA,ISO,ISS)
synaptonemal complex  (IDA)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Association of mammalian SMC1 and SMC3 proteins with meiotic chromosomes and synaptonemal complexes. Eijpe M, etal., J Cell Sci 2000 Feb;113 ( Pt 4):673-82.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Full spectrum of clonal haematopoiesis-driver mutations in chronic heart failure and their associations with mortality. Kiefer KC, etal., ESC Heart Fail. 2021 Jun;8(3):1873-1884. doi: 10.1002/ehf2.13297. Epub 2021 Mar 28.
4. Trans-resveratrol imparts disparate effects on transcription of DNA damage sensing/repair pathway genes in euglycemic and hyperglycemic rat testis. Kilarkaje N, etal., Toxicol Appl Pharmacol. 2021 May 1;418:115510. doi: 10.1016/j.taap.2021.115510. Epub 2021 Mar 26.
5. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
6. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
7. GOA pipeline RGD automated data pipeline
8. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
10. Tentative Sequence Identification Numbers Tentative Sequence Data IDs. TIGR Gene Index, Rat Data
Additional References at PubMed
PMID:9789013   PMID:10375619   PMID:11076961   PMID:11590136   PMID:11682612   PMID:11877377   PMID:12199140   PMID:12759374   PMID:15917200   PMID:17932228   PMID:20075618   PMID:20720539  
PMID:21242291   PMID:21527826   PMID:22415368   PMID:22628566   PMID:22681889   PMID:23242214   PMID:23638217   PMID:31505169  


Genomics

Comparative Map Data
Smc1a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X24,582,732 - 24,627,462 (+)NCBIGRCr8
mRatBN7.2X21,103,323 - 21,148,053 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX21,103,282 - 21,148,056 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX18,580,342 - 18,625,072 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X21,498,503 - 21,543,222 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X21,668,965 - 21,713,695 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X21,710,976 - 21,755,708 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX21,711,019 - 21,755,525 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X21,691,592 - 21,736,383 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X41,503,393 - 41,547,830 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1X41,556,861 - 41,601,299 (+)NCBI
CeleraX21,378,634 - 21,423,365 (+)NCBICelera
Cytogenetic MapXq13NCBI
SMC1A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X53,374,149 - 53,422,728 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX53,374,149 - 53,422,728 (-)EnsemblGRCh38hg38GRCh38
GRCh37X53,401,070 - 53,449,677 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X53,417,795 - 53,466,343 (-)NCBINCBI36Build 36hg18NCBI36
Build 34X53,284,090 - 53,332,639NCBI
CeleraX57,232,626 - 57,281,175 (-)NCBICelera
Cytogenetic MapXp11.22NCBI
HuRefX50,459,360 - 50,507,305 (-)NCBIHuRef
CHM1_1X53,391,525 - 53,440,144 (-)NCBICHM1_1
T2T-CHM13v2.0X52,660,456 - 52,709,071 (-)NCBIT2T-CHM13v2.0
Smc1a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X150,799,386 - 150,844,969 (+)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX150,799,424 - 150,845,690 (+)EnsemblGRCm39 Ensembl
GRCm38X152,016,428 - 152,061,973 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX152,016,428 - 152,062,694 (+)EnsemblGRCm38mm10GRCm38
MGSCv37X148,450,971 - 148,496,516 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X147,357,144 - 147,402,683 (+)NCBIMGSCv36mm8
CeleraX132,369,172 - 132,413,610 (-)NCBICelera
Cytogenetic MapXF3NCBI
cM MapX68.46NCBI
Smc1a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955475421,409 - 468,324 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955475421,472 - 468,286 (-)NCBIChiLan1.0ChiLan1.0
SMC1A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X54,760,686 - 54,821,872 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X54,764,274 - 54,825,412 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X45,576,100 - 45,637,314 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X53,697,154 - 53,745,641 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX53,697,154 - 53,745,636 (-)Ensemblpanpan1.1panPan2
SMC1A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X45,099,312 - 45,148,103 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX45,109,653 - 45,148,001 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX36,633,229 - 36,682,028 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0X45,424,145 - 45,472,953 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX45,427,836 - 45,472,912 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X44,919,324 - 44,968,108 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X45,368,982 - 45,417,772 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X45,436,314 - 45,485,351 (-)NCBIUU_Cfam_GSD_1.0
Smc1a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X37,992,636 - 38,049,030 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936751349,597 - 388,755 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936751332,351 - 388,756 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
SMC1A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX46,144,920 - 46,218,543 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X46,143,738 - 46,202,187 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X51,643,473 - 51,702,113 (-)NCBISscrofa10.2Sscrofa10.2susScr3
SMC1A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X49,514,652 - 49,558,490 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 EnsemblX49,515,061 - 49,558,447 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660863,466,124 - 3,511,145 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Smc1a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624909630,062 - 668,512 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624909617,015 - 668,513 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Smc1a
85 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:31
Count of miRNA genes:31
Interacting mature miRNAs:31
Transcripts:ENSRNOT00000004364
Prediction methods:Miranda, Pita, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1598873Memor2Memory QTL 22.5exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)X2099094741052531Rat
70165Bp64Blood pressure QTL 645.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)X144812931706553Rat
1298071Edpm12Estrogen-dependent pituitary mass QTL 123.2pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)X292789847927898Rat
2290375Gluco34Glucose level QTL 342.75blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)X2099094741203591Rat
731181Uae27Urinary albumin excretion QTL 272.70.0059urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)X143491017Rat
61430Cia18Collagen induced arthritis QTL 183.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)X14843113120568734Rat
10755455Coatc13Coat color QTL 130coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)7440600049406000Rat
631666Iddm5Insulin dependent diabetes mellitus QTL 5blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)X449454949494549Rat
631204Gluco15Glucose level QTL 150.001blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)X162371522646544Rat
71116Niddm16Non-insulin dependent diabetes mellitus QTL 167.81blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)X1529780260297802Rat

Markers in Region
RH129456  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2X21,147,403 - 21,147,935 (+)MAPPERmRatBN7.2
Rnor_6.0X21,755,059 - 21,755,590NCBIRnor6.0
Rnor_5.0X21,691,710 - 21,692,241UniSTSRnor5.0
RGSC_v3.4X41,547,181 - 41,547,712UniSTSRGSC3.4
CeleraX21,422,716 - 21,423,247UniSTS
RH 3.4 Map321.9UniSTS
Cytogenetic MapXq21.3UniSTS
RH129467  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2X21,147,872 - 21,148,027 (+)MAPPERmRatBN7.2
Rnor_6.0X21,755,528 - 21,755,682NCBIRnor6.0
Rnor_5.0X21,691,618 - 21,691,772UniSTSRnor5.0
RGSC_v3.4X41,547,650 - 41,547,804UniSTSRGSC3.4
CeleraX21,423,185 - 21,423,339UniSTS
RH 3.4 MapX170.42UniSTS
Cytogenetic MapXq21.3UniSTS
RH143344  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2X21,141,579 - 21,141,804 (+)MAPPERmRatBN7.2
Rnor_6.0X21,749,233 - 21,749,457NCBIRnor6.0
Rnor_5.0X21,697,902 - 21,698,126UniSTSRnor5.0
RGSC_v3.4X41,541,650 - 41,541,874UniSTSRGSC3.4
CeleraX21,416,892 - 21,417,116UniSTS
Cytogenetic MapXq21.3UniSTS
DXS423  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2X21,112,525 - 21,112,627 (+)MAPPERmRatBN7.2
Rnor_6.0X21,720,179 - 21,720,280NCBIRnor6.0
Rnor_5.0X21,727,078 - 21,727,180NCBIRnor5.0
RGSC_v3.4X41,512,596 - 41,512,697UniSTSRGSC3.4
CeleraX21,387,838 - 21,387,939UniSTS
Cytogenetic MapXq21.3UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000004364   ⟹   ENSRNOP00000004364
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX21,103,282 - 21,148,056 (+)Ensembl
Rnor_6.0 EnsemblX21,711,019 - 21,755,525 (+)Ensembl
RefSeq Acc Id: NM_031683   ⟹   NP_113871
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X24,582,732 - 24,627,462 (+)NCBI
mRatBN7.2X21,103,323 - 21,148,053 (+)NCBI
Rnor_6.0X21,710,976 - 21,755,708 (+)NCBI
Rnor_5.0X21,691,592 - 21,736,383 (-)NCBI
RGSC_v3.4X41,503,393 - 41,547,830 (+)RGD
CeleraX21,378,634 - 21,423,365 (+)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_113871 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein CAA06377 (Get FASTA)   NCBI Sequence Viewer  
  EDL86307 (Get FASTA)   NCBI Sequence Viewer  
  EDL86308 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000004364.7
GenBank Protein Q9Z1M9 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_113871   ⟸   NM_031683
- UniProtKB: Q9Z1M9 (UniProtKB/Swiss-Prot),   F1LSS1 (UniProtKB/TrEMBL),   A6KLB2 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000004364   ⟸   ENSRNOT00000004364
Protein Domains
SMC hinge

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9Z1M9-F1-model_v2 AlphaFold Q9Z1M9 1-1233 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13701770
Promoter ID:EPDNEW_R12294
Type:initiation region
Name:Smc1a_1
Description:structural maintenance of chromosomes 1A
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0X21,710,959 - 21,711,019EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:61991 AgrOrtholog
BioCyc Gene G2FUF-2718 BioCyc
Ensembl Genes ENSRNOG00000003139 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000004364.8 UniProtKB/TrEMBL
Gene3D-CATH 1.20.1060.20 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.30.70.1620 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.40.50.300 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro P-loop_NTPase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RecF/RecN/SMC_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SMC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Smc1_ABC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SMC_hinge UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SMC_hinge_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:63996 UniProtKB/Swiss-Prot
NCBI Gene 63996 ENTREZGENE
PANTHER PTHR18937:SF170 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  STRUCTURAL MAINTENANCE OF CHROMOSOMES SMC FAMILY MEMBER UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam SMC_hinge UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SMC_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Smc1a PhenoGen
PIRSF SMC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000003139 RatGTEx
SMART SMC_hinge UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF75553 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
TIGR TC218064
UniProt A6KLB2 ENTREZGENE, UniProtKB/TrEMBL
  F1LSS1 ENTREZGENE, UniProtKB/TrEMBL
  Q9Z1M9 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-02-18 Smc1a  structural maintenance of chromosomes 1A  Smc1l1  structural maintenance of chromosomes 1 like 1 (S. cerevisiae)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-12-14 Smc1l1  structural maintenance of chromosomes 1 like 1 (S. cerevisiae)    SMC-like 1 (yeast)   Name updated 1299863 APPROVED
2002-06-10 Smc1l1  SMC-like 1 (yeast)       Name updated 70585 PROVISIONAL
2002-02-06 Sb1.8  KIAA0178 protein      object retired and merged with Smc1l1 (RGD:61991) 62408 WITHDRAWN
2002-02-06 DXhXs423e  KIAA0178 protein      object retired and merged with Smc1l1 (RGD:61991) 62408 WITHDRAWN

RGD Curation Notes
Note Type Note Reference