Gpr83 (G protein-coupled receptor 83)

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Gene: Gpr83 (G protein-coupled receptor 83) Rattus norvegicus

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Symbol:

Gpr83

Name:

G protein-coupled receptor 83

RGD ID:

619891

Description:

Predicted to enable neuropeptide receptor activity. Predicted to be involved in feeding behavior; neuropeptide signaling pathway; and phospholipase C-activating G protein-coupled receptor signaling pathway. Predicted to act upstream of or within response to glucocorticoid. Predicted to be located in non-motile cilium. Predicted to be active in plasma membrane. Orthologous to human GPR83 (G protein-coupled receptor 83); INTERACTS WITH (S)-amphetamine; (S)-nicotine; alpha-Zearalanol.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

G-protein coupled receptor 83; Gir; glucocorticoid-induced receptor; probable G-protein coupled receptor 83

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	GPR83 (G protein-coupled receptor 83)	HGNC	EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther, PhylomeDB
Mus musculus (house mouse):	Gpr83 (G protein-coupled receptor 83)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Gpr83 (G protein-coupled receptor 83)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	GPR83 (G protein-coupled receptor 83)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	GPR83 (G protein-coupled receptor 83)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Gpr83 (G protein-coupled receptor 83)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	GPR83 (G protein-coupled receptor 83)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	GPR83 (G protein-coupled receptor 83)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Gpr83 (G protein-coupled receptor 83)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Mus musculus (house mouse):	Gpr83 (G protein-coupled receptor 83)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	GPR83 (G protein-coupled receptor 83)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	si:dkey-27p18.2	Alliance	DIOPT (InParanoid\|OMA\|OrthoInspector\|PANTHER\|SonicParanoid)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	8	19,974,995 - 19,985,483 (+)	NCBI		GRCr8
mRatBN7.2	8	11,693,540 - 11,704,028 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	8	11,693,540 - 11,704,028 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	8	15,678,274 - 15,688,779 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	8	13,976,020 - 13,986,525 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	8	11,951,920 - 11,962,328 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	8	13,365,583 - 13,376,071 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	8	13,365,583 - 13,376,070 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	8	13,306,230 - 13,316,718 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	8	11,648,755 - 11,659,242 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	8	11,648,754 - 11,659,241 (+)	NCBI
Celera	8	13,163,211 - 13,173,699 (+)	NCBI		Celera
Cytogenetic Map	8	q12	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

intellectual disability (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(S)-amphetamine (EXP)

(S)-nicotine (EXP)

1,2-dimethylhydrazine (ISO)

17alpha-ethynylestradiol (ISO)

alpha-Zearalanol (EXP)

ammonium acetate (EXP)

ammonium chloride (EXP)

amphetamine (EXP)

aristolochic acid A (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

cannabidiol (ISO)

cytarabine (ISO)

dexamethasone (ISO)

dextran sulfate (ISO)

ethanol (ISO)

fenvalerate (EXP)

fonofos (ISO)

genistein (ISO)

hydralazine (ISO)

medroxyprogesterone acetate (ISO)

N-methyl-4-phenylpyridinium (ISO)

nicotine (EXP)

paracetamol (ISO)

parathion (ISO)

perfluorononanoic acid (ISO)

perfluorooctanoic acid (ISO)

quercetin (ISO)

quercitrin (ISO)

resveratrol (ISO)

sodium arsenite (ISO)

tamoxifen (ISO)

terbufos (ISO)

testosterone (ISO)

Theaflavin 3,3'-digallate (ISO)

titanium dioxide (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

feeding behavior (IEA,ISO)

G protein-coupled receptor signaling pathway (IEA,ISO)

neuropeptide signaling pathway (IBA,IEA,ISO)

phospholipase C-activating G protein-coupled receptor signaling pathway (IEA,ISO)

response to glucocorticoid (IEA,ISO)

Cellular Component

cilium (ISO)

non-motile cilium (IEA,ISO)

plasma membrane (IBA,IEA,ISO)

Molecular Function

G protein-coupled receptor activity (IEA,ISO)

neuropeptide receptor activity (IBA,ISO)

neuropeptide Y receptor activity (IEA)

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
3.	Electronic Transfer of LocusLink and RefSeq Data	NCBI rat LocusLink and RefSeq merged data July 26, 2002
4.	GOA pipeline	RGD automated data pipeline
5.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
7.	Cloning, expression, and regulation of a glucocorticoid-induced receptor in rat brain: effect of repetitive amphetamine.	Wang D, etal., J Neurosci 2001 Nov 15;21(22):9027-35.

Additional References at PubMed

PMID:1663214	PMID:12444039	PMID:24316073	PMID:28154160

Genomics

Comparative Map Data

Gpr83
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	8	19,974,995 - 19,985,483 (+)	NCBI		GRCr8
mRatBN7.2	8	11,693,540 - 11,704,028 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	8	11,693,540 - 11,704,028 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	8	15,678,274 - 15,688,779 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	8	13,976,020 - 13,986,525 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	8	11,951,920 - 11,962,328 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	8	13,365,583 - 13,376,071 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	8	13,365,583 - 13,376,070 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	8	13,306,230 - 13,316,718 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	8	11,648,755 - 11,659,242 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	8	11,648,754 - 11,659,241 (+)	NCBI
Celera	8	13,163,211 - 13,173,699 (+)	NCBI		Celera
Cytogenetic Map	8	q12	NCBI

GPR83
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	11	94,377,316 - 94,401,419 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	11	94,377,316 - 94,401,419 (-)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	11	94,110,482 - 94,134,585 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	11	93,750,131 - 93,774,066 (-)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	11	93,750,130 - 93,774,066	NCBI
Celera	11	91,398,304 - 91,422,417 (-)	NCBI		Celera
Cytogenetic Map	11	q21	NCBI
HuRef	11	90,176,011 - 90,200,120 (-)	NCBI		HuRef
CHM1_1	11	93,993,488 - 94,017,596 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	11	94,384,353 - 94,408,454 (-)	NCBI		T2T-CHM13v2.0

Gpr83
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	9	14,771,038 - 14,782,085 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	9	14,771,506 - 14,782,085 (+)	Ensembl		GRCm39 Ensembl
GRCm38	9	14,859,880 - 14,870,789 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	9	14,860,210 - 14,870,789 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	9	14,664,698 - 14,673,943 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	9	14,610,647 - 14,619,892 (+)	NCBI		MGSCv36	mm8
Celera	9	12,141,017 - 12,150,262 (+)	NCBI		Celera
Cytogenetic Map	9	A2	NCBI
cM Map	9	4.4	NCBI

Gpr83
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955414	216,397 - 229,659 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955414	216,867 - 229,659 (+)	NCBI	ChiLan1.0	ChiLan1.0

GPR83
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	9	95,220,695 - 95,246,902 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	11	96,312,430 - 96,336,943 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	11	89,380,290 - 89,405,039 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	11	92,868,031 - 92,890,048 (-)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	11	92,868,849 - 92,889,827 (-)	Ensembl	panpan1.1		panPan2

GPR83
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	21	6,536,486 - 6,546,859 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	21	6,536,485 - 6,546,859 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	21	6,546,809 - 6,557,281 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	21	6,716,881 - 6,727,371 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	21	6,717,197 - 6,729,283 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	21	6,497,570 - 6,508,038 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	21	6,566,679 - 6,577,094 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	21	6,616,620 - 6,627,114 (+)	NCBI		UU_Cfam_GSD_1.0

Gpr83
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404947	79,337,231 - 79,349,563 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936674	541,934 - 553,677 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936674	541,934 - 553,191 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

GPR83
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	9	26,548,594 - 26,560,473 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	9	26,549,230 - 26,560,473 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	9	30,303,221 - 30,317,362 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

GPR83
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	1	85,577,620 - 85,597,780 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	1	85,583,039 - 85,597,423 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666043	40,179,904 - 40,195,769 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Gpr83
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624735	39,049,761 - 39,061,730 (-)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624735	39,049,652 - 39,062,198 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Gpr83
55 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	264
Count of miRNA genes:	183
Interacting mature miRNAs:	222
Transcripts:	ENSRNOT00000044945
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1357398	Slep3	Serum leptin concentration QTL 3	3.43		blood leptin amount (VT:0005667)	serum leptin level (CMO:0000780)	8	9712463	41866876	Rat
2317030	Wbc5	White blood cell count QTL 5	3.21	0.005	leukocyte quantity (VT:0000217)	white blood cell count (CMO:0000027)	8	8736635	53736635	Rat
12880044	Am9	Aortic mass QTL 9		0.007	aorta mass (VT:0002845)	aorta weight to aorta length to body weight ratio (CMO:0002722)	8	2097640	47097640	Rat
2317032	Ginf2	Gastrointestinal inflammation QTL 2	3.21	0.005	liver integrity trait (VT:0010547)	liver granuloma severity score (CMO:0002157)	8	4705810	49705810	Rat
2301416	Bp315	Blood pressure QTL 315		0.008	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	8	7670578	52670578	Rat
631650	Stl6	Serum triglyceride level QTL 6	4	0.0019	blood triglyceride amount (VT:0002644)	plasma triglyceride level (CMO:0000548)	8	10378157	112202585	Rat
1581557	Eae16	Experimental allergic encephalomyelitis QTL 16	3.8		nervous system integrity trait (VT:0010566)	experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)	8	8462195	110921472	Rat
2317036	Livw3	Liver weight QTL 3	2.43	0.01	liver mass (VT:0003402)	liver weight to body weight ratio (CMO:0000633)	8	4705810	49705810	Rat
1598824	Memor4	Memory QTL 4	2.5		exploratory behavior trait (VT:0010471)	total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)	8	9712220	53356647	Rat
12880023	Bw184	Body weight QTL 184		0.001	body mass (VT:0001259)	body weight (CMO:0000012)	8	2097640	47097640	Rat
9590084	Insglur5	Insulin/glucose ratio QTL 5	18.54	0.001	blood insulin amount (VT:0001560)	calculated plasma insulin level (CMO:0002170)	8	1	24597739	Rat
1354595	Despr4	Despair related QTL 4	2.16	0.0036	locomotor behavior trait (VT:0001392)	amount of time spent in voluntary immobility (CMO:0001043)	8	7688955	52688955	Rat
1354627	Despr14	Despair related QTL 14		0.0056	locomotor behavior trait (VT:0001392)	amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)	8	7688955	52688955	Rat
12880028	Cm103	Cardiac mass QTL 103		0.02	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	8	2097640	47097640	Rat
2317051	Aia18	Adjuvant induced arthritis QTL 18	2.42		joint integrity trait (VT:0010548)	left rear ankle joint diameter (CMO:0002149)	8	8736635	53736635	Rat
2317882	Alcrsp24	Alcohol response QTL 24	3.2	0.05	response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	8	1	25902202	Rat
2317048	Ginf1	Gastrointestinal inflammation QTL 1	3.52	0.005	cecum mucosa thickness (VT:0010234)	enterocolitis severity score (CMO:0002138)	8	4705810	49705810	Rat
2302367	Slep5	Serum leptin concentration QTL 5	3.43		blood leptin amount (VT:0005667)	serum leptin level (CMO:0000780)	8	9712463	41866876	Rat
12880025	Cm102	Cardiac mass QTL 102		0.044	heart mass (VT:0007028)	heart wet weight to body weight ratio (CMO:0002408)	8	2097640	47097640	Rat

Markers in Region

RH137605

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	8	11,703,836 - 11,703,956 (+)	MAPPER	mRatBN7.2
Rnor_6.0	8	13,375,880 - 13,375,999	NCBI	Rnor6.0
Rnor_5.0	8	13,316,527 - 13,316,646	UniSTS	Rnor5.0
RGSC_v3.4	8	11,659,051 - 11,659,170	UniSTS	RGSC3.4
Celera	8	13,173,508 - 13,173,627	UniSTS
Cytogenetic Map	8	q11	UniSTS

AI102409

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	8	11,702,392 - 11,702,551 (+)	MAPPER	mRatBN7.2
Rnor_6.0	8	13,374,436 - 13,374,594	NCBI	Rnor6.0
Rnor_5.0	8	13,315,083 - 13,315,241	UniSTS	Rnor5.0
RGSC_v3.4	8	11,657,608 - 11,657,766	UniSTS	RGSC3.4
Celera	8	13,172,064 - 13,172,222	UniSTS
RH 3.4 Map	8	0.0	UniSTS
Cytogenetic Map	8	q11	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
9	7	35	111	72	67	40	19	40	6	156	75	91	27	55	27

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_080411	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC097778	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AY029071	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473993	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	DQ218279	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000008	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000044945 ⟹ ENSRNOP00000043707

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	8	11,693,540 - 11,704,027 (+)	Ensembl
Rnor_6.0 Ensembl	8	13,365,583 - 13,376,070 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000107459 ⟹ ENSRNOP00000081584

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	8	11,693,540 - 11,704,028 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000112516 ⟹ ENSRNOP00000089985

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	8	11,693,846 - 11,704,027 (+)	Ensembl

RefSeq Acc Id:

NM_080411 ⟹ NP_536336

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	8	19,974,995 - 19,985,483 (+)	NCBI
mRatBN7.2	8	11,693,540 - 11,704,028 (+)	NCBI
Rnor_6.0	8	13,365,583 - 13,376,071 (+)	NCBI
Rnor_5.0	8	13,306,230 - 13,316,718 (+)	NCBI
RGSC_v3.4	8	11,648,755 - 11,659,242 (+)	RGD
Celera	8	13,163,211 - 13,173,699 (+)	RGD

Sequence:

show sequence

GACCGAGGACCGAGGTGGGTGACAGTCCGCACAATCCCTAGGTTCCCTAGGATCCCTAGGTTTT
CCGGAGTTCTCCCTGCGGTCCGGACCCTCCTGAGGATCTCGGTTGTCTCCCCATCCAGGACCTG
GCGTCCCCAGGTTCTCTCGGAGGTCGGGGCTCCCTCTATGCTTCGCGCCCCTCGAGTCCAGGTT
CCCTCTGTGGTGCGGACTCCTCTAGCCCGGTGCGCTCAGCACCCTGCACCCAGTCTCCTCATAC
GGAGCCTGGCGGGGAGTCCGGACCTTGTGTCCAGAGCTGCAGTGGTTGGACATGAATGTCCCTC
CTGTCCTGCTTCTTTTTCTTCTGTCCTCCGTGAGAGCCACTGAGCAGCCGCAGGTCGTCACTGA
GCATCCCAGCATGGATGCAGCCCTGACCGGAGCCAATGCCTCGCATTTCTGGGCCAACTACACT
TTCTCTGACTGGCAGAACTTCGTGGGCAGGAGACGCTATGGGGCTGAGTCCCAGAACCCCACAG
TGAAAGCCCTGCTCATCGTGGCCTACTCCTTCATCATTGTCTTCTCGCTCTTCGGCAATGTCCT
GGTCTGTCATGTAATCTTCAAGAACCAGCGTATGCACTCGGCCACCAGCCTCTTCATCGTCAAC
CTGGCAGTGGCAGACATCATGATCACATTGCTCAACACGCCCTTCACTTTGGTCCGCTTTGTGA
ACAGCACATGGGTGTTTGGGAAGGGCATGTGTCATGTCAGCCGCTTTGCCCAGTACTGTTCTCT
ACATGTCTCAGCACTGACCCTGACAGCTATCGCAGTGGACCGCCACCAGGTCATCATGCATCCC
TTGAAGCCTCGGATCTCCATCACCAAGGGTGTCATATATATTGCTGTCATCTGGGTCATGGCTA
CCTTCTTCTCTCTGCCTCATGCCATCTGCCAGAAACTGTTTACCTTCAAGTACAGTGAGGACAT
TGTGCGCTCCCTCTGCCTGCCGGACTTCCCAGAGCCAGCTGACCTCTTTTGGAAGTACCTGGAC
CTGGCCACCTTCATCCTACTCTACCTCCTTCCACTCTTCATTATCTCAGTGGCCTATGCTCGTG
TGGCCAAGAAATTGTGGCTCTGCAACACTATTGGCGACGTGACCACAGAGCAGTACCTCGCCCT
GAGACGCAAGAAGAAGACCACCGTGAAGATGCTGGTGCTTGTGGTGGTCCTCTTCGCTCTCTGC
TGGTTCCCCCTCAACTGCTATGTCCTCCTTCTGTCCAGCAAGGCCATCCACACCAACAACGCCC
TCTACTTTGCCTTCCACTGGTTTGCCATGAGCAGCACTTGTTATAATCCCTTCATCTACTGCTG
GCTCAACGAGAACTTCAGGGTGGAGCTGAAGGCACTGTTGAGCATGTGCCAGAGGCCGTCCAAG
CCTCAGGAAGACAGGCTGCCCTCCCCGGTTCCTTCCTTCAGGGTGGCATGGACGGAGAAGAGCC
ATGGTCGGAGGGCTCTGCTAGCTAATCACCACCTTCCCTCTTCCCAGATCCAGTCTGGGAAGAC
AGATCTGTCCTCTGTGGAACCCACTGTGGCCGTGAGTTAGGGGAAGCTGGAAGTGGTGGGAGAG
GGTTCTGTCCTCTCACAATTGACCAGACTCAAGGTGTCGGAAAGTTCCCCAGAATCAGTGAGAT
GCTTGGGTTCCTAGGAACCTGTCCAGCACCCTCTGGTTTGCAAACCTTGTAGAAGATACCATGA
GGTGTTGTGTGTGGATCTTTGAGCAAGAGCTCCGGAAGCCACCTCAGCTCCAGCAGAGGCTGGT
TCAGTCAACCCCTGTCAGTTGTATAGCATCTGCCACCTTTGTCCTTCCTTCTGCTGAGCACCCA
CAGCAGGACCCGGGTCACATTATTGGTAGGCCTGACGCATGTGCTCAGAAAAGAACTTCACTAG
CCAGGGAGAACAGGCATGGAGGCCTTCTGAAGTCATTGGGGCAAGTCCAATCACACAGCTTCAA
TGGCCTTGGCTCTGTCTATGCCAGACAGGGCCCATCTTGGTTTCTTAAAATAGAAATTAGTATT
GCCATTTTGAAAAGGTCAAAAAGGGAAAGAAATTAATTCAGCCCCATCGATTTGTTAAAAAAAA
AAAGCCTGTTAATATGCTGTGAATTTATCTGTAACTTTGCCTTCTCTATGTGTGCACATTTGTA
CTTTTAAAGTCATGAACTACATGTATCCATTTAGATTGTAATAATTAGCAAGAAATAGGGATAT
ATTGGAGTACTATTGAATTCCTCCATGACAAATGGGGTCCCTCAGCATATGAGAAGAGAAGAGA
GGAGAGGAGAGGAGGGTAGGGGAGGGGAGAGGAGAGGAGAGGAGAGGAGGGGAGAGGAAGGGAA
GGGAGTGGAGGGGAGAGGAGAAGTAAGCAAGGTGAGGGTTGGATCAACTCTACCTTGTAACTAG
TGATGGGTGGGGCCTGGCCCTCTCCTAGGTGGTTACCATCAAGATGAGCAGTGCACCAGAGAGC
CGGGAGGTAGGCTCCCTTTCTCCTGACCCCCAGAAAGAAGAAGGGGTGAATCACTGTTCCCTTT
TAATGGACAATGTGGGACTTGCTTTCCAATAAGCTGGAAATAATTGTGCTTAGACACCTCATCT
GCCCAAGATGTCTAGACAGGGCATTTTTCTCCATTGTCTGAATGATGAAAAACTTTTTCACACC
AGTTCCAGAGAGAAGATTTCCCTGTCTACATCACCTGAGAAATTCATGTGTCATTTTTAAAAAA
CTTACAGGCTTCTTGAAGCCGCTCTATTCCTCGAGGGCCCCTTTGTCAGAGAAATCTCATTCCA
GGTGCCCAGTGATTTCGCCATCTTCCATGTGGTCCCGATGACTCTCAGTGTTCCCCACTGACAG
CTGTGCCAGGCAGAACTGACTCCAATCCCCATGCCCAGAGCCATGGCTGCTGCGCTAGCATCGG
ATTCCCACCTCCTCCTCACAGAGCCACCACAGAGACAAGCCATCTTTGTGGAGCTGAGAGGGAA
ACTGAGGCTCAAGGGAGGAGAGGCTCATCCAAGACTCATTTAGAACTCTCAGTTGCTAACTGAA
GCACAATCTGCTTAAGTCTGATTCCCTCTAACAAACCTGGGGGGTTGCTTAAACTAGTCTGTCC
ATAGGAGTGTTAGAAAAAAATCCAAGATAAAAAAAAATGTCATCTATAGAACATCAGTTTGTTT
AAAAAAAATGTTTTGGAGAGGGTAGATTTCCAAATATAAAGTGAGTTTTTGAGGCCACAGCTTC
TGCATCTGTCCTATCTCTGTATTGTCAGCTGGTACCTGGGAGTTTCATCTTTCATGTGGCCAAG
AAGAGTCATGGTACTAACCTGAGGACAGGCAGCAGCAACACACAGTGTGTCTTCCCCTAGGGAC
TTGTGGGAGGAGCTTCAGCCATAGCTCCCAGAGGGCAGCTGGAGACAGCACCCTGTCACAGAGT
CAGCCATCAGATCTGCATCTCTTGTCCGTCCCCATCTGCTCCCTTCCTTGTATGCCGTCGGAGC
AGACGTGACTGGTAACAGTGACTGTGGTCTTTGTGAAGCCTGGGTTTTTCCAATATGCTGCAAA
GTGTGCTTTATTGTGAGTCACCATAGGCGCAATAAAACCTCTCCTCTGTGTGCAAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_536336	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAK29999	(Get FASTA)	NCBI Sequence Viewer
	EDL78460	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000043707.1
	ENSRNOP00000081584.1
	ENSRNOP00000089985.1
	ENSRNOP00055009029
	ENSRNOP00060006967
	ENSRNOP00065015005
GenBank Protein	Q8VHD7	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:	NP_536336 ⟸ NM_080411
- Peptide Label:	precursor
- UniProtKB:	Q8VHD7 (UniProtKB/TrEMBL), A0A8I5ZSC1 (UniProtKB/TrEMBL)
- Sequence:	show sequence MNVPPVLLLFLLSSVRATEQPQVVTEHPSMDAALTGANASHFWANYTFSDWQNFVGRRRYGAES QNPTVKALLIVAYSFIIVFSLFGNVLVCHVIFKNQRMHSATSLFIVNLAVADIMITLLNTPFTL VRFVNSTWVFGKGMCHVSRFAQYCSLHVSALTLTAIAVDRHQVIMHPLKPRISITKGVIYIAVI WVMATFFSLPHAICQKLFTFKYSEDIVRSLCLPDFPEPADLFWKYLDLATFILLYLLPLFIISV AYARVAKKLWLCNTIGDVTTEQYLALRRKKKTTVKMLVLVVVLFALCWFPLNCYVLLLSSKAIH TNNALYFAFHWFAMSSTCYNPFIYCWLNENFRVELKALLSMCQRPSKPQEDRLPSPVPSFRVAW TEKSHGRRALLANHHLPSSQIQSGKTDLSSVEPTVAVS hide sequence

Ensembl Acc Id:

ENSRNOP00000043707 ⟸ ENSRNOT00000044945

Ensembl Acc Id:

ENSRNOP00000081584 ⟸ ENSRNOT00000107459

Ensembl Acc Id:

ENSRNOP00000089985 ⟸ ENSRNOT00000112516

Protein Domains

G-protein coupled receptors family 1 profile

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q8VHD7-F1-model_v2	AlphaFold	Q8VHD7	1-422	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:619891	AgrOrtholog
BioCyc Gene	G2FUF-31681	BioCyc
Ensembl Genes	ENSRNOG00000030318	Ensembl, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	ENSRNOG00055006959	UniProtKB/Swiss-Prot
	ENSRNOG00060005568	UniProtKB/Swiss-Prot
	ENSRNOG00065012029	UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000044945.3	UniProtKB/Swiss-Prot
	ENSRNOT00000107459.1	UniProtKB/TrEMBL
	ENSRNOT00000112516.1	UniProtKB/TrEMBL
	ENSRNOT00055011482	UniProtKB/Swiss-Prot
	ENSRNOT00060009262	UniProtKB/Swiss-Prot
	ENSRNOT00065019571	UniProtKB/Swiss-Prot
Gene3D-CATH	Rhodopsin 7-helix transmembrane proteins	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro	GPCR_Rhodpsn	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	GPCR_Rhodpsn_7TM	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	NPY_rcpt	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	rno:140595	UniProtKB/Swiss-Prot
NCBI Gene	140595	ENTREZGENE
PANTHER	G-PROTEIN COUPLED RECEPTOR	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	G-PROTEIN COUPLED RECEPTOR 83	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	7tm_1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Gpr83	PhenoGen
PRINTS	GPCRRHODOPSN	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	NRPEPTIDEYR	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE	G_PROTEIN_RECEP_F1_1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	G_PROTEIN_RECEP_F1_2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000030318	RatGTEx
	ENSRNOG00055006959	RatGTEx
	ENSRNOG00060005568	RatGTEx
	ENSRNOG00065012029	RatGTEx
SMART	7TM_GPCR_Srsx	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP	Family A G protein-coupled receptor-like	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	A0A8I5ZSC1	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6GHU3_RAT	UniProtKB/TrEMBL
	GPR83_RAT	UniProtKB/Swiss-Prot, ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2005-01-20	Gpr83	G protein-coupled receptor 83			Symbol and Name status set to approved	1299863	APPROVED
2002-08-07	Gpr83	G protein-coupled receptor 83			Symbol and Name status set to provisional	70820	PROVISIONAL

RGD Curation Notes

Note Type	Note	Reference
gene_product	member of the G-protein-coupled receptor superfamily and the peptide receptor subfamily	632827
gene_protein	422 amino acid	632827

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar