Arhgef11 (Rho guanine nucleotide exchange factor 11) - Rat Genome Database

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Pathways
Gene: Arhgef11 (Rho guanine nucleotide exchange factor 11) Rattus norvegicus
Analyze
Symbol: Arhgef11
Name: Rho guanine nucleotide exchange factor 11
RGD ID: 619705
Description: Enables guanyl-nucleotide exchange factor activity. Involved in positive regulation of L-glutamate import across plasma membrane. Predicted to be located in nucleoplasm and plasma membrane. Predicted to be active in cytoplasm. Orthologous to human ARHGEF11 (Rho guanine nucleotide exchange factor 11); INTERACTS WITH 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: glutamate transporter EAAT4 associated protein 48; Gtrap48; Rho guanine nucleotide exchange factor (GEF) 11; RhoGEF glutamate transport modulator GTRAP48
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Allele / Splice: Arhgef11em4Mcwi ; Arhgef11em5Mcwi
Genetic Models: SS-Arhgef11em5Mcwi ; SS-Arhgef11em4Mcwi
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82175,372,269 - 175,493,852 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl2175,372,290 - 175,493,852 (+)EnsemblGRCr8
mRatBN7.22173,074,383 - 173,195,962 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2173,074,368 - 173,196,010 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx2180,224,015 - 180,343,253 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02178,246,357 - 178,365,598 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02172,835,607 - 172,955,106 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.02186,979,850 - 187,102,523 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2186,980,793 - 187,101,768 (+)Ensemblrn6Rnor6.0
Rnor_5.02206,384,799 - 206,507,431 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.42179,676,236 - 179,796,785 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera2167,024,592 - 167,144,568 (+)NCBICelera
RGSC_v3.12179,626,341 - 179,746,891 (+)NCBI
Cytogenetic Map2q34NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IBA,IEA,ISO)
membrane  (IEA)
nucleoplasm  (IEA,ISO)
plasma membrane  (IEA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Recognition of the activated states of Galpha13 by the rgRGS domain of PDZRhoGEF. Chen Z, etal., Structure. 2008 Oct 8;16(10):1532-43. doi: 10.1016/j.str.2008.07.009.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
4. Increased PDZ-RhoGEF/RhoA/Rho kinase signaling in small mesenteric arteries of angiotensin II-induced hypertensive rats. Hilgers RH, etal., J Hypertens. 2007 Aug;25(8):1687-97.
5. Modulation of the neuronal glutamate transporter EAAT4 by two interacting proteins. Jackson M, etal., Nature 2001 Mar 1;410(6824):89-93.
6. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
7. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
8. GOA pipeline RGD automated data pipeline
9. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
10. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10026210   PMID:15755723   PMID:18226120   PMID:20739613   PMID:22987919   PMID:23696743   PMID:24106280   PMID:26172442   PMID:31612150   PMID:32148127  


Genomics

Comparative Map Data
Arhgef11
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82175,372,269 - 175,493,852 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl2175,372,290 - 175,493,852 (+)EnsemblGRCr8
mRatBN7.22173,074,383 - 173,195,962 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2173,074,368 - 173,196,010 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx2180,224,015 - 180,343,253 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02178,246,357 - 178,365,598 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02172,835,607 - 172,955,106 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.02186,979,850 - 187,102,523 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2186,980,793 - 187,101,768 (+)Ensemblrn6Rnor6.0
Rnor_5.02206,384,799 - 206,507,431 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.42179,676,236 - 179,796,785 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera2167,024,592 - 167,144,568 (+)NCBICelera
RGSC_v3.12179,626,341 - 179,746,891 (+)NCBI
Cytogenetic Map2q34NCBI
ARHGEF11
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381156,934,840 - 157,046,903 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1156,934,840 - 157,046,903 (-)Ensemblhg38GRCh38
GRCh371156,904,632 - 157,016,695 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361155,171,256 - 155,281,786 (-)NCBIBuild 36Build 36hg18NCBI36
Build 341153,717,705 - 153,828,235NCBI
Celera1129,975,863 - 130,086,340 (-)NCBICelera
Cytogenetic Map1q23.1NCBI
HuRef1128,263,003 - 128,403,804 (-)NCBIHuRef
CHM1_11158,301,064 - 158,411,558 (-)NCBICHM1_1
T2T-CHM13v2.01156,071,681 - 156,183,721 (-)NCBIT2T-CHM13v2.0
Arhgef11
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39387,524,855 - 87,645,346 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl387,524,866 - 87,645,341 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38387,617,548 - 87,738,039 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl387,617,559 - 87,738,034 (+)Ensemblmm10GRCm38
MGSCv37387,422,673 - 87,541,955 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36387,704,678 - 87,823,960 (+)NCBIMGSCv36mm8
Celera387,655,238 - 87,774,229 (+)NCBICelera
Cytogenetic Map3F1NCBI
cM Map338.22NCBI
Arhgef11
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555452,989,774 - 3,097,003 (-)Ensembl
ChiLan1.0NW_0049555452,988,676 - 3,099,159 (-)NCBIChiLan1.0ChiLan1.0
ARHGEF11
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2192,797,589 - 92,910,122 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1192,532,333 - 92,644,715 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01132,277,514 - 132,390,041 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11136,100,575 - 136,210,253 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1136,101,732 - 136,208,896 (-)EnsemblpanPan2panpan1.1
ARHGEF11
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1741,011,956 - 41,098,134 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl741,011,830 - 41,097,487 (+)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha740,499,160 - 40,585,236 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0740,874,361 - 40,960,526 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl740,874,219 - 40,960,633 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1740,656,641 - 40,742,722 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0740,709,544 - 40,795,782 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0740,992,902 - 41,079,222 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Arhgef11
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505827,036,196 - 27,147,213 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365806,067,429 - 6,177,601 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365806,066,577 - 6,177,595 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ARHGEF11
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl493,046,770 - 93,160,084 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1493,045,533 - 93,160,756 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.24101,684,353 - 101,732,762 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ARHGEF11
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1206,825,331 - 6,935,110 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl206,883,815 - 6,933,961 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236660386,100,669 - 6,210,618 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Arhgef11
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248852,043,672 - 2,171,491 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046248852,042,718 - 2,171,368 (-)NCBIHetGla 1.0HetGla 1.0hetGla2

Variants

.
Variants in Arhgef11
560 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:80
Count of miRNA genes:70
Interacting mature miRNAs:79
Transcripts:ENSRNOT00000020717
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1358356Srcrt1Stress Responsive Cort QTL13.66blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)2163997722225110681Rat
1578648Bss11Bone structure and strength QTL 114.7femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)2169358774214358774Rat
1331734Bp204Blood pressure QTL 2043.61192arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2170656145239614549Rat
631566Bp90Blood pressure QTL 900.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2149957381221199885Rat
1298074Bp164Blood pressure QTL 1640.003arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)244537979205135428Rat
1354648Bp239Blood pressure QTL 2390.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)267845370229470703Rat
1354649Kidm17Kidney mass QTL 172.9kidney mass (VT:0002707)calculated kidney weight (CMO:0000160)283465462229820014Rat
10755499Bp389Blood pressure QTL 3892.61arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)220695736231474293Rat
1298076Bp166Blood pressure QTL 1660.0009arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2138595962205135428Rat
1581576Pur7Proteinuria QTL 70.0001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)280396178220931218Rat
152025245Scl81Serum cholesterol level QTL 813.49blood cholesterol amount (VT:0000180)2124537199209621565Rat
1581578Cm49Cardiac mass QTL 494.90.01heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)2145807215220931416Rat
631198Cm22Cardiac mass QTL 224.30.0008heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)278269809208420281Rat
1554319Bmd2Bone mineral density QTL 213.40.0001lumbar vertebra area (VT:0010570)lumbar vertebra cross-sectional area (CMO:0001689)2122597372215234002Rat
12879836Kidm61Kidney mass QTL 610.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)2154723085199723085Rat
1581569Uae32Urinary albumin excretion QTL 320.0001urine protein amount (VT:0005160)urine albumin excretion rate (CMO:0000757)280396178220931218Rat
10043136Iddm54Insulin dependent diabetes mellitus QTL 543.40.0001blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)2145807215190807215Rat
12879837Am2Aortic mass QTL 20.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)2154723085199723085Rat
10043139Iddm55Insulin dependent diabetes mellitus QTL 553.10.0001blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)2150313808195313808Rat
12879838Cm86Cardiac mass QTL 860.002heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)2154723085199723085Rat
1302793Bw16Body weight QTL 1650.0001body mass (VT:0001259)body weight (CMO:0000012)2159440891205135267Rat
12879839Cm85Cardiac mass QTL 850.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)2154723085199723085Rat
1549833Bp257Blood pressure QTL 2570.003arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2170652929215652929Rat
1358900Bw48Body weight QTL 484.88body mass (VT:0001259)body weight (CMO:0000012)2159440891220931218Rat
4889834Pur24Proteinuria QTL 245.80.014urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)2171994826205135428Rat
12879845Cm89Cardiac mass QTL 890.008heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)2154723085178247591Rat
61473Bp19Blood pressure QTL 196.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2175008837178247591Rat
1359030Bp277Blood pressure QTL 277arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)2143565208188565208Rat
12879846Cm90Cardiac mass QTL 900.011heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)2154723085178247591Rat
12879847Am4Aortic mass QTL 40.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)2154723085178247591Rat
7771605Memor19Memory QTL 190.00001exploratory behavior trait (VT:0010471)measurement of voluntary locomotion into, out of or within a discrete space in an experimental apparatus (CMO:0000957)2172499769175588177Rat
1331760Bp206Blood pressure QTL 2063.62454arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)24265106205135428Rat
12879840Bw179Body weight QTL 1790.005body mass (VT:0001259)body weight (CMO:0000012)2154723085199723085Rat
7771603Bp371Blood pressure QTL 3710.00001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2172499769175588177Rat
1581502Esta3Estrogen-induced thymic atrophy QTL 3thymus mass (VT:0004954)thymus wet weight (CMO:0000855)2139067258192287892Rat
1359032Hrtrt18Heart rate QTL 18heart pumping trait (VT:2000009)heart rate (CMO:0000002)2159440760195313808Rat
2301966Bp322Blood pressure QTL 3223.58arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2144882354205135428Rat
1298080Bp163Blood pressure QTL 1630.02arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)267845182205135428Rat
1357991Ael2Aortic elastin QTL 24.20.000071aorta elastin amount (VT:0003905)aortic elastin2169227906214227906Rat
8662832Vetf7Vascular elastic tissue fragility QTL 73.5aorta elastin amount (VT:0003905)aorta wall extracellular elastin dry weight to aorta wall dry weight ratio (CMO:0002002)283400752223709938Rat
1298085Bp165Blood pressure QTL 1650.0006arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)244537979205135428Rat
1359022Ppulsi1Prepulse inhibition QTL 13.63prepulse inhibition trait (VT:0003088)acoustic startle response measurement (CMO:0001519)2139067258184067258Rat
1641891Alcrsp17Alcohol response QTL 17response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)2151869660251712708Rat
724534Uae6Urinary albumin excretion QTL 610urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)280396034220931416Rat
61374Edpm2Estrogen-dependent pituitary mass QTL 24.420.86pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)278269809205135428Rat
8662843Vetf9Vascular elastic tissue fragility QTL 92.05thoracic aorta molecular composition trait (VT:0010568)aorta wall extracellular elastin dry weight to aorta wall extracellular collagen weight ratio (CMO:0002003)2159440760228950743Rat
2301415Cm67Cardiac mass QTL 670.003heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)2154723085178247591Rat
1331794Bp202Blood pressure QTL 2023.66819arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2143344967251712708Rat
71113Cari2Carrageenan-induced inflammation QTL 22.70.009hypodermis integrity trait (VT:0010550)inflammatory exudate volume (CMO:0001429)2143746578205135428Rat
1331805Cm29Cardiac mass QTL 293.50746heart mass (VT:0007028)heart wet weight (CMO:0000069)2143344967251712708Rat
11565180Kidm56Kidney mass QTL 560.003kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)2154723085178247591Rat
634308Sach6Saccharin preference QTL 64.9taste sensitivity trait (VT:0001986)saccharin intake volume to total fluid intake volume ratio (CMO:0001601)2114384617215381366Rat
1598805Memor8Memory QTL 83exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)2150096616195096616Rat
11565181Bw176Body weight QTL 1760.002body mass (VT:0001259)body weight (CMO:0000012)2154723085178247591Rat
1358917Cm42Cardiac mass QTL 422.82heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)227148328206613235Rat
724568Uae13Urinary albumin excretion QTL 134.4urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)2145306936212705578Rat
1358913Cm41Cardiac mass QTL 412.73heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)227148328206613235Rat
1300165Rf9Renal function QTL 93.28kidney glomerulus integrity trait (VT:0010546)index of glomerular damage (CMO:0001135)2113746222205135428Rat
61401Niddm2Non-insulin dependent diabetes mellitus QTL 24.54blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)2147287892192287892Rat
631507Bp105Blood pressure QTL 1050.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2114384617215381366Rat
1641925Alcrsp2Alcohol response QTL 2response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)2151869660223841096Rat
1354609Niddm62Non-insulin dependent diabetes mellitus QTL 624.720.000006insulin secretion trait (VT:0003564)plasma insulin level (CMO:0000342)2117415288205135428Rat
1598833Bp295Blood pressure QTL 2953.5arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2150096616195096616Rat
1354622Kidm16Kidney mass QTL 163kidney mass (VT:0002707)left kidney wet weight (CMO:0000083)283465462225110681Rat
631266Bp132Blood pressure QTL 1320.0005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)247856345205135428Rat
631522Bp74Blood pressure QTL 740.05arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2175008837220008837Rat
7488927Bp365Blood pressure QTL 3650.008arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2165453811210453811Rat
7488925Bp364Blood pressure QTL 3640.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2163253030208253030Rat
2293843Kiddil6Kidney dilation QTL 63.1kidney pelvis morphology trait (VT:0004194)hydronephrosis severity score (CMO:0001208)244537979184731399Rat
2306901Bp337Blood pressure QTL 3370.01arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)2166372086229820014Rat
1354605Rf48Renal function QTL 482.9blood creatinine amount (VT:0005328)plasma creatinine level (CMO:0000537)276328396209350714Rat
7488904Bp363Blood pressure QTL 3630.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)2175279960178247591Rat

Markers in Region
D2Mco45  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22173,103,977 - 173,104,221 (+)MAPPERmRatBN7.2
Rnor_6.02187,009,630 - 187,009,873NCBIRnor6.0
Rnor_5.02206,414,549 - 206,414,792UniSTSRnor5.0
RGSC_v3.42179,704,792 - 179,705,036RGDRGSC3.4
RGSC_v3.42179,704,793 - 179,705,036UniSTSRGSC3.4
Celera2167,052,956 - 167,053,199UniSTS
Cytogenetic Map2q34UniSTS
BI289089  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.22173,194,055 - 173,194,162 (+)MAPPERmRatBN7.2
Rnor_6.02187,100,617 - 187,100,723NCBIRnor6.0
Rnor_5.02206,505,525 - 206,505,631UniSTSRnor5.0
RGSC_v3.42179,795,831 - 179,795,937UniSTSRGSC3.4
Celera2167,143,614 - 167,143,720UniSTS
RH 3.4 Map21130.4UniSTS
Cytogenetic Map2q34UniSTS


Genetic Models
This gene Arhgef11 is modified in the following models/strains:


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 163 91 90 59 92 59 6 355 192 11 142 80 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_023982 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006232759 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006232766 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008761214 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008761215 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008761216 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008761217 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008761219 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008761220 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008761222 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008761223 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008761224 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008761225 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017591126 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039103176 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039103177 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039103178 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039103179 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039103180 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039103181 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039103182 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039103183 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039103184 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039103185 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039103186 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039103187 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039103188 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039103189 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063282598 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063282599 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063282600 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063282601 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063282602 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063282603 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063282604 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063282605 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063282606 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC119000 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF225961 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473976 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000002 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000020717   ⟹   ENSRNOP00000020717
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl2175,436,812 - 175,491,777 (+)Ensembl
mRatBN7.2 Ensembl2173,138,916 - 173,193,887 (+)Ensembl
Rnor_6.0 Ensembl2186,980,992 - 187,101,571 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000091336   ⟹   ENSRNOP00000070996
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl2175,436,812 - 175,491,777 (+)Ensembl
mRatBN7.2 Ensembl2173,138,916 - 173,193,887 (+)Ensembl
Rnor_6.0 Ensembl2186,980,793 - 187,101,768 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000106820   ⟹   ENSRNOP00000086384
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl2175,372,290 - 175,493,852 (+)Ensembl
mRatBN7.2 Ensembl2173,074,368 - 173,196,010 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000114540   ⟹   ENSRNOP00000086176
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl2175,372,290 - 175,493,852 (+)Ensembl
mRatBN7.2 Ensembl2173,074,402 - 173,196,010 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000116714   ⟹   ENSRNOP00000088812
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl2175,373,291 - 175,493,852 (+)Ensembl
mRatBN7.2 Ensembl2173,074,389 - 173,196,010 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000119098   ⟹   ENSRNOP00000083614
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl2175,372,290 - 175,493,852 (+)Ensembl
mRatBN7.2 Ensembl2173,074,373 - 173,196,010 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000157908   ⟹   ENSRNOP00000108218
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl2175,373,291 - 175,493,852 (+)Ensembl
RefSeq Acc Id: NM_023982   ⟹   NP_076472
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82175,372,290 - 175,493,852 (+)NCBI
mRatBN7.22173,074,395 - 173,195,962 (+)NCBI
Rnor_6.02186,980,992 - 187,101,571 (+)NCBI
Rnor_5.02206,384,799 - 206,507,431 (+)NCBI
RGSC_v3.42179,676,236 - 179,796,785 (+)RGD
Celera2167,024,592 - 167,144,568 (+)RGD
Sequence:
RefSeq Acc Id: XM_006232759   ⟹   XP_006232821
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82175,372,269 - 175,493,852 (+)NCBI
mRatBN7.22173,074,385 - 173,195,962 (+)NCBI
Rnor_6.02186,979,850 - 187,102,523 (+)NCBI
Rnor_5.02206,384,799 - 206,507,431 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006232766   ⟹   XP_006232828
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82175,372,269 - 175,493,852 (+)NCBI
mRatBN7.22173,074,385 - 173,195,962 (+)NCBI
Rnor_6.02186,979,850 - 187,102,523 (+)NCBI
Rnor_5.02206,384,799 - 206,507,431 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017591126   ⟹   XP_017446615
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82175,372,269 - 175,493,852 (+)NCBI
mRatBN7.22173,074,385 - 173,195,962 (+)NCBI
Rnor_6.02186,979,850 - 187,102,523 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039103176   ⟹   XP_038959104
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82175,372,269 - 175,493,852 (+)NCBI
mRatBN7.22173,074,385 - 173,195,962 (+)NCBI
RefSeq Acc Id: XM_039103177   ⟹   XP_038959105
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82175,372,269 - 175,493,852 (+)NCBI
mRatBN7.22173,074,383 - 173,195,962 (+)NCBI
RefSeq Acc Id: XM_039103178   ⟹   XP_038959106
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82175,372,269 - 175,493,852 (+)NCBI
mRatBN7.22173,074,383 - 173,195,962 (+)NCBI
RefSeq Acc Id: XM_039103179   ⟹   XP_038959107
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82175,372,269 - 175,493,852 (+)NCBI
mRatBN7.22173,074,383 - 173,195,962 (+)NCBI
RefSeq Acc Id: XM_039103180   ⟹   XP_038959108
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82175,372,269 - 175,493,852 (+)NCBI
mRatBN7.22173,074,385 - 173,195,962 (+)NCBI
RefSeq Acc Id: XM_039103181   ⟹   XP_038959109
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82175,372,269 - 175,493,852 (+)NCBI
mRatBN7.22173,074,385 - 173,195,962 (+)NCBI
RefSeq Acc Id: XM_039103182   ⟹   XP_038959110
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82175,372,269 - 175,493,852 (+)NCBI
mRatBN7.22173,074,383 - 173,195,962 (+)NCBI
RefSeq Acc Id: XM_039103183   ⟹   XP_038959111
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82175,372,269 - 175,493,852 (+)NCBI
mRatBN7.22173,074,383 - 173,195,962 (+)NCBI
RefSeq Acc Id: XM_039103184   ⟹   XP_038959112
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82175,372,269 - 175,493,852 (+)NCBI
mRatBN7.22173,074,385 - 173,195,962 (+)NCBI
RefSeq Acc Id: XM_039103185   ⟹   XP_038959113
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82175,372,269 - 175,493,852 (+)NCBI
mRatBN7.22173,074,384 - 173,195,962 (+)NCBI
RefSeq Acc Id: XM_039103186   ⟹   XP_038959114
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82175,372,269 - 175,493,852 (+)NCBI
mRatBN7.22173,074,383 - 173,195,962 (+)NCBI
RefSeq Acc Id: XM_039103187   ⟹   XP_038959115
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82175,372,269 - 175,493,852 (+)NCBI
mRatBN7.22173,074,383 - 173,195,962 (+)NCBI
RefSeq Acc Id: XM_039103188   ⟹   XP_038959116
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82175,372,269 - 175,493,852 (+)NCBI
mRatBN7.22173,074,385 - 173,195,962 (+)NCBI
RefSeq Acc Id: XM_039103189   ⟹   XP_038959117
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82175,372,269 - 175,493,852 (+)NCBI
mRatBN7.22173,074,385 - 173,195,962 (+)NCBI
RefSeq Acc Id: XM_063282598   ⟹   XP_063138668
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82175,372,269 - 175,493,852 (+)NCBI
RefSeq Acc Id: XM_063282599   ⟹   XP_063138669
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82175,372,269 - 175,493,852 (+)NCBI
RefSeq Acc Id: XM_063282600   ⟹   XP_063138670
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82175,372,269 - 175,493,852 (+)NCBI
RefSeq Acc Id: XM_063282601   ⟹   XP_063138671
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82175,372,269 - 175,493,852 (+)NCBI
RefSeq Acc Id: XM_063282602   ⟹   XP_063138672
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82175,372,269 - 175,493,852 (+)NCBI
RefSeq Acc Id: XM_063282603   ⟹   XP_063138673
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82175,372,269 - 175,493,852 (+)NCBI
RefSeq Acc Id: XM_063282604   ⟹   XP_063138674
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82175,372,269 - 175,493,852 (+)NCBI
RefSeq Acc Id: XM_063282605   ⟹   XP_063138675
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82175,372,269 - 175,493,852 (+)NCBI
RefSeq Acc Id: XM_063282606   ⟹   XP_063138676
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr82175,372,269 - 175,488,295 (+)NCBI
Protein Sequences
Protein RefSeqs NP_076472 (Get FASTA)   NCBI Sequence Viewer  
  XP_006232821 (Get FASTA)   NCBI Sequence Viewer  
  XP_006232828 (Get FASTA)   NCBI Sequence Viewer  
  XP_017446615 (Get FASTA)   NCBI Sequence Viewer  
  XP_038959104 (Get FASTA)   NCBI Sequence Viewer  
  XP_038959105 (Get FASTA)   NCBI Sequence Viewer  
  XP_038959106 (Get FASTA)   NCBI Sequence Viewer  
  XP_038959107 (Get FASTA)   NCBI Sequence Viewer  
  XP_038959108 (Get FASTA)   NCBI Sequence Viewer  
  XP_038959109 (Get FASTA)   NCBI Sequence Viewer  
  XP_038959110 (Get FASTA)   NCBI Sequence Viewer  
  XP_038959111 (Get FASTA)   NCBI Sequence Viewer  
  XP_038959112 (Get FASTA)   NCBI Sequence Viewer  
  XP_038959113 (Get FASTA)   NCBI Sequence Viewer  
  XP_038959114 (Get FASTA)   NCBI Sequence Viewer  
  XP_038959115 (Get FASTA)   NCBI Sequence Viewer  
  XP_038959116 (Get FASTA)   NCBI Sequence Viewer  
  XP_038959117 (Get FASTA)   NCBI Sequence Viewer  
  XP_063138668 (Get FASTA)   NCBI Sequence Viewer  
  XP_063138669 (Get FASTA)   NCBI Sequence Viewer  
  XP_063138670 (Get FASTA)   NCBI Sequence Viewer  
  XP_063138671 (Get FASTA)   NCBI Sequence Viewer  
  XP_063138672 (Get FASTA)   NCBI Sequence Viewer  
  XP_063138673 (Get FASTA)   NCBI Sequence Viewer  
  XP_063138674 (Get FASTA)   NCBI Sequence Viewer  
  XP_063138675 (Get FASTA)   NCBI Sequence Viewer  
  XP_063138676 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAG28597 (Get FASTA)   NCBI Sequence Viewer  
  EDM00775 (Get FASTA)   NCBI Sequence Viewer  
  EDM00776 (Get FASTA)   NCBI Sequence Viewer  
  EDM00777 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000020717
  ENSRNOP00000070996
  ENSRNOP00000083614
  ENSRNOP00000086176
  ENSRNOP00000086384
  ENSRNOP00000088812
  ENSRNOP00000108218
GenBank Protein Q9ES67 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_076472   ⟸   NM_023982
- UniProtKB: Q9ES67 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006232821   ⟸   XM_006232759
- Peptide Label: isoform X1
- UniProtKB: A0A8I6AAM2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006232828   ⟸   XM_006232766
- Peptide Label: isoform X11
- UniProtKB: A0A8I6A5B5 (UniProtKB/TrEMBL),   A0A8I6AAM2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017446615   ⟸   XM_017591126
- Peptide Label: isoform X5
- UniProtKB: A0A8I6AAM2 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000020717   ⟸   ENSRNOT00000020717
Ensembl Acc Id: ENSRNOP00000070996   ⟸   ENSRNOT00000091336
RefSeq Acc Id: XP_038959105   ⟸   XM_039103177
- Peptide Label: isoform X2
- UniProtKB: A0A8I6AAM2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038959106   ⟸   XM_039103178
- Peptide Label: isoform X4
- UniProtKB: A0A8I6AAM2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038959110   ⟸   XM_039103182
- Peptide Label: isoform X9
- UniProtKB: Q9ES67 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_038959114   ⟸   XM_039103186
- Peptide Label: isoform X18
- UniProtKB: Q9ES67 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_038959115   ⟸   XM_039103187
- Peptide Label: isoform X19
- UniProtKB: Q9ES67 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_038959107   ⟸   XM_039103179
- Peptide Label: isoform X6
- UniProtKB: A0A8I6AAM2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038959111   ⟸   XM_039103183
- Peptide Label: isoform X13
- UniProtKB: A0A8I6AAM2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038959113   ⟸   XM_039103185
- Peptide Label: isoform X16
- UniProtKB: A0A8I6AAM2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038959108   ⟸   XM_039103180
- Peptide Label: isoform X7
- UniProtKB: Q9ES67 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_038959104   ⟸   XM_039103176
- Peptide Label: isoform X3
- UniProtKB: A0A8I6AAM2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038959109   ⟸   XM_039103181
- Peptide Label: isoform X8
- UniProtKB: Q9ES67 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_038959116   ⟸   XM_039103188
- Peptide Label: isoform X20
- UniProtKB: A0A8I6AAM2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038959112   ⟸   XM_039103184
- Peptide Label: isoform X17
- UniProtKB: Q9ES67 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_038959117   ⟸   XM_039103189
- Peptide Label: isoform X25
- UniProtKB: Q9ES67 (UniProtKB/Swiss-Prot)
Ensembl Acc Id: ENSRNOP00000083614   ⟸   ENSRNOT00000119098
Ensembl Acc Id: ENSRNOP00000086384   ⟸   ENSRNOT00000106820
Ensembl Acc Id: ENSRNOP00000088812   ⟸   ENSRNOT00000116714
Ensembl Acc Id: ENSRNOP00000086176   ⟸   ENSRNOT00000114540
RefSeq Acc Id: XP_063138668   ⟸   XM_063282598
- Peptide Label: isoform X10
- UniProtKB: Q9ES67 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_063138670   ⟸   XM_063282600
- Peptide Label: isoform X14
- UniProtKB: A0A8I6A8L7 (UniProtKB/TrEMBL),   A0A8I6AAM2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063138669   ⟸   XM_063282599
- Peptide Label: isoform X12
- UniProtKB: A0A8I6AAM2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063138671   ⟸   XM_063282601
- Peptide Label: isoform X15
- UniProtKB: A0A8I6AAM2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063138672   ⟸   XM_063282602
- Peptide Label: isoform X21
- UniProtKB: Q9ES67 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_063138674   ⟸   XM_063282604
- Peptide Label: isoform X23
- UniProtKB: Q9ES67 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_063138673   ⟸   XM_063282603
- Peptide Label: isoform X22
- UniProtKB: Q9ES67 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_063138675   ⟸   XM_063282605
- Peptide Label: isoform X24
- UniProtKB: Q9ES67 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_063138676   ⟸   XM_063282606
- Peptide Label: isoform X26
Ensembl Acc Id: ENSRNOP00000108218   ⟸   ENSRNOT00000157908
Protein Domains
DH   PDZ   PH   RGS   RGSL

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9ES67-F1-model_v2 AlphaFold Q9ES67 1-1527 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:619705 AgrOrtholog
BioCyc Gene G2FUF-52538 BioCyc
Ensembl Genes ENSRNOG00000015026 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000020717 ENTREZGENE
  ENSRNOT00000091336 ENTREZGENE
  ENSRNOT00000106820 ENTREZGENE
  ENSRNOT00000114540 ENTREZGENE
  ENSRNOT00000116714 ENTREZGENE
  ENSRNOT00000119098 ENTREZGENE
  ENSRNOT00000157908 ENTREZGENE
Gene3D-CATH 1.10.167.10 UniProtKB/Swiss-Prot
  1.20.900.10 UniProtKB/Swiss-Prot
  2.30.29.30 UniProtKB/Swiss-Prot
  2.30.42.10 UniProtKB/Swiss-Prot
InterPro DBL_dom_sf UniProtKB/Swiss-Prot
  DH-domain UniProtKB/Swiss-Prot
  GDS_CDC24_CS UniProtKB/Swiss-Prot
  PDZ UniProtKB/Swiss-Prot
  PDZ_sf UniProtKB/Swiss-Prot
  PDZRhoGEF_RGS UniProtKB/Swiss-Prot
  PH-like_dom_sf UniProtKB/Swiss-Prot
  PH_16 UniProtKB/Swiss-Prot
  PH_domain UniProtKB/Swiss-Prot
  PRG_PH UniProtKB/Swiss-Prot
  RGS UniProtKB/Swiss-Prot
  RGS-like_dom UniProtKB/Swiss-Prot
  RGS_sf UniProtKB/Swiss-Prot
  RGS_subdomain_2 UniProtKB/Swiss-Prot
KEGG Report rno:78966 UniProtKB/Swiss-Prot
NCBI Gene 78966 ENTREZGENE
PANTHER PTHR45872:SF1 UniProtKB/Swiss-Prot
  RHO GUANINE NUCLEOTIDE EXCHANGE FACTOR 2, ISOFORM D UniProtKB/Swiss-Prot
Pfam PDZ UniProtKB/Swiss-Prot
  PH_16 UniProtKB/Swiss-Prot
  RGS-like UniProtKB/Swiss-Prot
  RhoGEF UniProtKB/Swiss-Prot
PhenoGen Arhgef11 PhenoGen
PROSITE DH_1 UniProtKB/Swiss-Prot
  DH_2 UniProtKB/Swiss-Prot
  PDZ UniProtKB/Swiss-Prot
  PH_DOMAIN UniProtKB/Swiss-Prot
  RGS UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000015026 RatGTEx
SMART PDZ UniProtKB/Swiss-Prot
  RGS UniProtKB/Swiss-Prot
  RhoGEF UniProtKB/Swiss-Prot
  SM00233 UniProtKB/Swiss-Prot
Superfamily-SCOP PH domain-like UniProtKB/Swiss-Prot
  SSF48065 UniProtKB/Swiss-Prot
  SSF48097 UniProtKB/Swiss-Prot
  SSF50156 UniProtKB/Swiss-Prot
UniProt A0A0G2JZC6_RAT UniProtKB/TrEMBL
  A0A8I5ZXJ6_RAT UniProtKB/TrEMBL
  A0A8I6A5B5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6A8L7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AAM2 ENTREZGENE, UniProtKB/TrEMBL
  A6J612_RAT UniProtKB/TrEMBL
  A6J613_RAT UniProtKB/TrEMBL
  A6J614_RAT UniProtKB/TrEMBL
  ARHGB_RAT UniProtKB/Swiss-Prot
  F1LQS9_RAT UniProtKB/TrEMBL
  Q9ES67 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-11-19 Arhgef11  Rho guanine nucleotide exchange factor 11  Arhgef11  Rho guanine nucleotide exchange factor (GEF) 11  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-09-10 Arhgef11  Rho guanine nucleotide exchange factor (GEF) 11  Gtrap48  RhoGEF glutamate transport modulator GTRAP48  Symbol and Name updated 1299863 APPROVED
2002-08-07 Gtrap48  RhoGEF glutamate transport modulator GTRAP48      Symbol and Name status set to provisional 70820 PROVISIONAL